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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9652781
log Bayes Factor = 17.8088
Chromosome 16   position 195,391  (GRCh37) Explore rs9652781 on Ensembl!
Variant rs9652781 is part of Cluster X0161

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.995 0.005 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.993 0.007 0.000
N17-N19 Renal failure
0.990 0.010 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.987 0.013 0.000
M50-M54 Other dorsopathies
0.986 0.014 0.000
Chapter I Certain infectious and parasitic diseases
0.980 0.020 0.000
M54 Dorsalgia
0.980 0.020 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.979 0.021 0.000
N84 Polyp of female genital tract
0.978 0.022 0.000
H25-H28 Disorders of lens
0.973 0.027 0.000
N93 Other abnormal uterine and vaginal bleeding
0.973 0.027 0.000
Chapter IX Diseases of the circulatory system
0.969 0.031 0.000
R06 Abnormalities of breathing
0.969 0.031 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.968 0.032 0.000
M20-M25 Other joint disorders
0.968 0.032 0.000
M80-M85 Disorders of bone density and structure
0.966 0.034 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.965 0.035 0.000
N84.0 Polyp of corpus uteri
0.965 0.035 0.000
E70-E90 Metabolic disorders
0.965 0.035 0.000
Chapter XXI Factors influencing health status and contact with health services
0.964 0.036 0.000
R06.0 Dyspnoea
0.963 0.037 0.000
H25 Senile cataract
0.960 0.040 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.958 0.042 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.956 0.044 0.000
Z50 Care involving use of rehabilitation procedures
0.952 0.048 0.000
M54.5 Low back pain
0.950 0.050 0.000
A30-A49 Other bacterial diseases
0.944 0.056 0.000
Chapter V Mental and behavioural disorders
0.942 0.058 0.000
R50-R69 General symptoms and signs
0.935 0.065 0.000
I60-I69 Cerebrovascular diseases
0.935 0.065 0.000
N19 Unspecified renal failure
0.934 0.066 0.000
H25.1 Senile nuclear cataract
0.931 0.069 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.928 0.072 0.000
E10-E14 Diabetes mellitus
0.927 0.073 0.000
H30-H36 Disorders of choroid and retina
0.923 0.077 0.000
N18 Chronic renal failure
0.920 0.080 0.000
O60-O75 Complications of labour and delivery
0.919 0.081 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.918 0.082 0.000
M05-M14 Inflammatory polyarthropathies
0.917 0.083 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.914 0.086 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.911 0.089 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.902 0.098 0.000
I63 Cerebral infarction
0.901 0.099 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.899 0.101 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.898 0.102 0.000
R11 Nausea and vomiting
0.896 0.104 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.894 0.106 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.894 0.106 0.000
E11 Non-insulin-dependent diabetes mellitus
0.892 0.108 0.000
M23 Internal derangement of knee
0.891 0.109 0.000
F41 Other anxiety disorders
0.888 0.112 0.000
M65-M68 Disorders of synovium and tendon
0.887 0.113 0.000
R00 Abnormalities of heart beat
0.886 0.114 0.000
N40-N51 Diseases of male genital organs
0.884 0.116 0.000
Z50.1 Other physical therapy
0.884 0.116 0.000
A41 Other septicaemia
0.884 0.116 0.000
L20-L30 Dermatitis and eczema
0.884 0.116 0.000
M81 Osteoporosis without pathological fracture
0.882 0.118 0.000
N00-N08 Glomerular diseases
0.882 0.118 0.000
O63 Long labour
0.882 0.118 0.000
Chapter XX External causes of morbidity and mortality
0.880 0.120 0.000
E65-E68 Obesity and other hyperalimentation
0.878 0.122 0.000
H43-H45 Disorders of vitreous body and globe
0.877 0.123 0.000
H25.8 Other senile cataract
0.877 0.123 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.877 0.123 0.000
Chapter VIII Diseases of the ear and mastoid process
0.874 0.126 0.000
M54.9 Dorsalgia, unspecified
0.873 0.127 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.871 0.128 0.000
M54.57 Low back pain (Lumbosacral region)
0.867 0.133 0.000
M91-M94 Chondropathies
0.864 0.136 0.000
M54.1 Radiculopathy
0.859 0.141 0.000
M45-M49 Spondylopathies
0.857 0.143 0.000
E86 Volume depletion
0.855 0.145 0.000
R56 Convulsions, not elsewhere classified
0.855 0.145 0.000
F43 Reaction to severe stress, and adjustment disorders
0.854 0.146 0.000
E11.9 Without complications
0.852 0.148 0.000
I26 Pulmonary embolism
0.851 0.149 0.000
N17 Acute renal failure
0.850 0.150 0.000
M54.59 Low back pain (Site unspecified)
0.848 0.152 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.848 0.152 0.000
D60-D64 Aplastic and other anaemias
0.848 0.152 0.000
M22 Disorders of patella
0.845 0.155 0.000
O63.1 Prolonged second stage (of labour)
0.845 0.155 0.000
Z47 Other orthopaedic follow-up care
0.845 0.155 0.000
M84 Disorders of continuity of bone
0.844 0.156 0.000
M15-M19 Arthrosis
0.844 0.156 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.843 0.157 0.000
M06 Other rheumatoid arthritis
0.843 0.157 0.000
E87.2 Acidosis
0.842 0.158 0.000
N18.9 Chronic renal failure, unspecified
0.842 0.158 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.842 0.158 0.000
I63.9 Cerebral infarction, unspecified
0.841 0.159 0.000
R00.0 Tachycardia, unspecified
0.840 0.160 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.837 0.163 0.000
H52 Disorders of refraction and accommodation
0.833 0.167 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.830 0.170 0.000
A49 Bacterial infection of unspecified site
0.830 0.170 0.000
H35 Other retinal disorders
0.829 0.171 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.828 0.172 0.000
A41.9 Septicaemia, unspecified
0.828 0.172 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.824 0.176 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.823 0.177 0.000
M81.9 Osteoporosis, unspecified
0.822 0.178 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.821 0.179 0.000
R04 Haemorrhage from respiratory passages
0.821 0.179 0.000
M65 Synovitis and tenosynovitis
0.820 0.180 0.000
N88 Other noninflammatory disorders of cervix uteri
0.820 0.180 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.818 0.182 0.000
R06.2 Wheezing
0.814 0.186 0.000
L60-L75 Disorders of skin appendages
0.813 0.187 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.812 0.188 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.809 0.191 0.000
F41.9 Anxiety disorder, unspecified
0.808 0.192 0.000
Z43 Attention to artificial openings
0.807 0.193 0.000
M24 Other specific joint derangements
0.807 0.193 0.000
H33 Retinal detachments and breaks
0.806 0.194 0.000
D80-D89 Certain disorders involving the immune mechanism
0.806 0.194 0.000
I10-I15 Hypertensive diseases
0.806 0.194 0.000
B35-B49 Mycoses
0.803 0.197 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.800 0.200 0.000
N02 Recurrent and persistent haematuria
0.798 0.202 0.000
H43 Disorders of vitreous body
0.798 0.202 0.000
R56.8 Other and unspecified convulsions
0.798 0.202 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.797 0.203 0.000
E66 Obesity
0.795 0.205 0.000
M70-M79 Other soft tissue disorders
0.795 0.205 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.794 0.206 0.000
R59 Enlarged lymph nodes
0.794 0.206 0.000
L03 Cellulitis
0.792 0.208 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.790 0.210 0.000
M06.9 Rheumatoid arthritis, unspecified
0.790 0.210 0.000
E50-E64 Other nutritional deficiencies
0.790 0.210 0.000
N18.4 Chronic kidney disease, stage 4
0.788 0.212 0.000
R57 Shock, not elsewhere classified
0.788 0.212 0.000
M80 Osteoporosis with pathological fracture
0.786 0.213 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.786 0.214 0.000
H25.9 Senile cataract, unspecified
0.782 0.218 0.000
M54.56 Low back pain (Lumbar region)
0.782 0.218 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.781 0.219 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.781 0.219 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.780 0.220 0.000
D64 Other anaemias
0.779 0.221 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.779 0.221 0.000
O72 Postpartum haemorrhage
0.777 0.223 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.775 0.225 0.000
O16 Unspecified maternal hypertension
0.775 0.225 0.000
R52 Pain, not elsewhere classified
0.774 0.225 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.773 0.227 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.773 0.227 0.000
R13 Dysphagia
0.773 0.227 0.000
D55-D59 Haemolytic anaemias
0.771 0.229 0.000
N25-N29 Other disorders of kidney and ureter
0.767 0.233 0.000
N95 Menopausal and other perimenopausal disorders
0.767 0.233 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.764 0.236 0.000
L50-L54 Urticaria and erythema
0.762 0.238 0.000
Z54 Convalescence
0.760 0.240 0.000
M20 Acquired deformities of fingers and toes
0.760 0.240 0.000
Z50.8 Care involving use of rehabilitation procedures
0.759 0.241 0.000
R12 Heartburn
0.757 0.243 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.757 0.243 0.000
F43.0 Acute stress reaction
0.756 0.244 0.000
R47-R49 Symptoms and signs involving speech and voice
0.755 0.245 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.752 0.248 0.000
M54.16 Radiculopathy (Lumbar region)
0.749 0.251 0.000
N17.9 Acute renal failure, unspecified
0.749 0.251 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.749 0.251 0.000
M18 Arthrosis of first carpometacarpal joint
0.749 0.251 0.000
N84.1 Polyp of cervix uteri
0.747 0.253 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.747 0.253 0.000
H65-H75 Diseases of middle ear and mastoid
0.746 0.254 0.000
H10-H13 Disorders of conjunctiva
0.744 0.255 0.000
M22.4 Chondromalacia patellae
0.744 0.256 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.743 0.257 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.743 0.257 0.000
M47 Spondylosis
0.741 0.259 0.000
M86-M90 Other osteopathies
0.740 0.260 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.740 0.260 0.000
R59.0 Localised enlarged lymph nodes
0.739 0.261 0.000
E87.0 Hyperosmolality and hypernatraemia
0.739 0.261 0.000
M54.4 Lumbago with sciatica
0.738 0.261 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.737 0.263 0.000
O61 Failed induction of labour
0.737 0.263 0.000
L57.0 Actinic keratosis
0.737 0.263 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.736 0.264 0.000
M31 Other necrotising vasculopathies
0.735 0.264 0.000
L30 Other dermatitis
0.734 0.266 0.000
M21 Other acquired deformities of limbs
0.732 0.268 0.000
R06.4 Hyperventilation
0.731 0.269 0.000
H33.3 Retinal breaks without detachment
0.731 0.269 0.000
D64.9 Anaemia, unspecified
0.730 0.270 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.729 0.271 0.000
I10 Essential (primary) hypertension
0.729 0.271 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.729 0.271 0.000
I62 Other nontraumatic intracranial haemorrhage
0.728 0.272 0.000
Z50.0 Cardiac rehabilitation
0.728 0.272 0.000
E66.9 Obesity, unspecified
0.725 0.275 0.000
M93 Other osteochondropathies
0.725 0.275 0.000
E14 Unspecified diabetes mellitus
0.725 0.275 0.000
F43.2 Adjustment disorders
0.724 0.276 0.000
R69 Unknown and unspecified causes of morbidity
0.724 0.276 0.000
L27 Dermatitis due to substances taken internally
0.724 0.276 0.000
E83 Disorders of mineral metabolism
0.724 0.276 0.000
E20-E35 Disorders of other endocrine glands
0.723 0.277 0.000
H52.1 Myopia
0.723 0.277 0.000
H43.8 Other disorders of vitreous body
0.722 0.278 0.000
H90-H95 Other disorders of ear
0.722 0.278 0.000
M54.2 Cervicalgia
0.721 0.279 0.000
R53 Malaise and fatigue
0.721 0.279 0.000
R29.6 Tendency to fall, not elsewhere classified
0.721 0.279 0.000
E88 Other metabolic disorders
0.721 0.279 0.000
Chapter II Neoplasms
0.720 0.280 0.000
B15-B19 Viral hepatitis
0.719 0.281 0.000
Z49 Care involving dialysis
0.719 0.281 0.000
H55-H59 Other disorders of eye and adnexa
0.718 0.282 0.000
Z29 Need for other prophylactic measures
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H35.3 Degeneration of macula and posterior pole
0.717 0.283 0.000
M50 Cervical disk disorders
0.717 0.283 0.000
Z52 Donors of organs and tissues
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.715 0.285 0.000
M81.98 Osteoporosis, unspecified (Other)
0.715 0.285 0.000
H52.2 Astigmatism
0.715 0.285 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.715 0.285 0.000
N90.5 Atrophy of vulva
0.714 0.286 0.000
E11.3 With ophthalmic complications
0.714 0.286 0.000
E40-E46 Malnutrition
0.713 0.287 0.000
N98 Complications associated with artificial fertilisation
0.712 0.288 0.000
N91 Absent, scanty and rare menstruation
0.712 0.288 0.000
N82 Fistulae involving female genital tract
0.712 0.288 0.000
N96 Habitual aborter
0.712 0.288 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.712 0.288 0.000
O80-O84 Delivery
0.709 0.291 0.000
L10-L14 Bullous disorders
0.708 0.292 0.000
D50-D53 Nutritional anaemias
0.708 0.292 0.000
N85.0 Endometrial glandular hyperplasia
0.708 0.292 0.000
H40-H42 Glaucoma
0.707 0.293 0.000
M53 Other dorsopathies, not elsewhere classified
0.707 0.293 0.000
M13 Other arthritis
0.707 0.293 0.000
N95.2 Postmenopausal atrophic vaginitis
0.707 0.293 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.706 0.294 0.000
Chapter XXII Codes for special purposes
0.704 0.295 0.000
F60-F69 Disorders of adult personality and behaviour
0.704 0.296 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.704 0.296 0.000
I69 Sequelae of cerebrovascular disease
0.703 0.297 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.703 0.297 0.000
O63.0 Prolonged first stage (of labour)
0.703 0.297 0.000
B99-B99 Other infectious diseases
0.703 0.297 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.703 0.297 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.703 0.297 0.000
B65-B83 Helminthiases
0.703 0.297 0.000
B50-B64 Protozoal diseases
0.703 0.297 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.703 0.297 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.703 0.297 0.000
A80-A89 Viral infections of the central nervous system
0.703 0.297 0.000
A75-A79 Rickettsioses
0.703 0.297 0.000
A70-A74 Other diseases caused by chlamydiae
0.703 0.297 0.000
A65-A69 Other spirochaetal diseases
0.703 0.297 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.703 0.297 0.000
A20-A28 Certain zoonotic bacterial diseases
0.703 0.297 0.000
A15-A19 Tuberculosis
0.703 0.297 0.000
M23.8 Other internal derangements of knee
0.703 0.297 0.000
M54.8 Other dorsalgia
0.702 0.298 0.000
M54.6 Pain in thoracic spine
0.702 0.298 0.000
M54.0 Panniculitis affecting regions of neck and back
0.702 0.298 0.000
N84.9 Polyp of female genital tract, unspecified
0.701 0.299 0.000
N84.8 Polyp of other parts of female genital tract
0.701 0.299 0.000
N84.3 Polyp of vulva
0.701 0.299 0.000
N84.2 Polyp of vagina
0.701 0.299 0.000
R02 Gangrene, not elsewhere classified
0.701 0.299 0.000
F80-F89 Disorders of psychological development
0.700 0.300 0.000
A49.9 Bacterial infection, unspecified
0.700 0.300 0.000
E87.7 Fluid overload
0.698 0.302 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.698 0.302 0.000
H27 Other disorders of lens
0.698 0.302 0.000
F41.2 Mixed anxiety and depressive disorder
0.697 0.303 0.000
M23.3 Other meniscus derangements
0.697 0.303 0.000
B07 Viral warts
0.697 0.303 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.696 0.304 0.000
O62 Abnormalities of forces of labour
0.696 0.304 0.000
F40 Phobic anxiety disorders
0.696 0.304 0.000
I00-I02 Acute rheumatic fever
0.695 0.305 0.000
N99-N99 Other disorders of the genitourinary system
0.695 0.305 0.000
R06.7 Sneezing
0.695 0.305 0.000
R06.6 Hiccough
0.695 0.305 0.000
R06.3 Periodic breathing
0.695 0.305 0.000
R06.1 Stridor
0.695 0.305 0.000
M94 Other disorders of cartilage
0.694 0.306 0.000
O85-O92 Complications predominantly related to the puerperium
0.694 0.306 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.694 0.306 0.000
M34 Systemic sclerosis
0.694 0.306 0.000
M33 Dermatopolymyositis
0.694 0.306 0.000
M32 Systemic lupus erythematosus
0.694 0.306 0.000
M30 Polyarteritis nodosa and related conditions
0.694 0.306 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.694 0.306 0.000
M11 Other crystal arthropathies
0.693 0.307 0.000
I63.8 Other cerebral infarction
0.693 0.307 0.000
Chapter X Diseases of the respiratory system
0.693 0.307 0.000
V40-V49 Car occupant injured in transport accident
0.693 0.307 0.000
M85 Other disorders of bone density and structure
0.692 0.307 0.000
M83 Adult osteomalacia
0.692 0.307 0.000
M82 Osteoporosis in diseases classified elsewhere
0.692 0.307 0.000
I73 Other peripheral vascular diseases
0.692 0.308 0.000
L40-L45 Papulosquamous disorders
0.692 0.308 0.000
H35.9 Retinal disorder, unspecified
0.692 0.308 0.000
B95-B98 Bacterial, viral and other infectious agents
0.692 0.308 0.000
E85 Amyloidosis
0.692 0.308 0.000
E84 Cystic fibrosis
0.692 0.308 0.000
E79 Disorders of purine and pyrimidine metabolism
0.692 0.308 0.000
E77 Disorders of glycoprotein metabolism
0.692 0.308 0.000
E76 Disorders of glycosaminoglycan metabolism
0.692 0.308 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.692 0.308 0.000
E74 Other disorders of carbohydrate metabolism
0.692 0.308 0.000
E73 Lactose intolerance
0.692 0.308 0.000
E72 Other disorders of amino-acid metabolism
0.692 0.308 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.692 0.308 0.000
E70 Disorders of aromatic amino-acid metabolism
0.692 0.308 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.692 0.308 0.000
M24.1 Other articular cartilage disorders
0.692 0.308 0.000
M45 Ankylosing spondylitis
0.692 0.308 0.000
L08 Other local infections of skin and subcutaneous tissue
0.691 0.309 0.000
D86 Sarcoidosis
0.691 0.309 0.000
R55 Syncope and collapse
0.691 0.309 0.000
I30-I52 Other forms of heart disease
0.691 0.309 0.000
F99-F99 Unspecified mental disorder
0.690 0.310 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.689 0.311 0.000
H25.2 Senile cataract, morgagnian type
0.688 0.312 0.000
N48 Other disorders of penis
0.688 0.312 0.000
R05 Cough
0.688 0.312 0.000
N94.3 Premenstrual tension syndrome
0.688 0.312 0.000
Z44 Fitting and adjustment of external prosthetic device
0.687 0.313 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.687 0.313 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.686 0.314 0.000
R60 Oedema, not elsewhere classified
0.684 0.316 0.000
B02 Zoster [herpes zoster]
0.683 0.317 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.683 0.317 0.000
B25-B34 Other viral diseases
0.683 0.317 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.683 0.317 0.000
N60-N64 Disorders of breast
0.683 0.317 0.000
Z50.6 Orthoptic training
0.683 0.317 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.683 0.317 0.000
Z50.3 Drug rehabilitation
0.683 0.317 0.000
Z50.2 Alcohol rehabilitation
0.683 0.317 0.000
N02.8 Other
0.683 0.317 0.000
R50 Fever of unknown origin
0.682 0.318 0.000
M54.55 Low back pain (Thoracolumbar region)
0.681 0.319 0.000
M54.54 Low back pain-Thoracic
0.681 0.319 0.000
M54.53 Low back pain-Cervicothoracic
0.681 0.319 0.000
M54.52 Low back pain-Cervical
0.681 0.319 0.000
M54.51 Low back pain-Occipit-atl-axl
0.681 0.319 0.000
M54.50 Low back pain (Multiple sites in spine)
0.681 0.319 0.000
N02.9 Unspecified
0.681 0.319 0.000
A49.0 Staphylococcal infection, unspecified
0.681 0.319 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.677 0.323 0.000
A48 Other bacterial diseases, not elsewhere classified
0.677 0.323 0.000
A44 Bartonellosis
0.677 0.323 0.000
A43 Nocardiosis
0.677 0.323 0.000
A42 Actinomycosis
0.677 0.323 0.000
A40 Streptococcal septicaemia
0.677 0.323 0.000
A39 Meningococcal infection
0.677 0.323 0.000
A37 Whooping cough
0.677 0.323 0.000
A36 Diphtheria
0.677 0.323 0.000
A32 Listeriosis
0.677 0.323 0.000
A31 Infection due to other mycobacteria
0.677 0.323 0.000
A30 Leprosy [Hansen's disease]
0.677 0.323 0.000
A46 Erysipelas
0.677 0.323 0.000
A38 Scarlet fever
0.677 0.323 0.000
A35 Other tetanus
0.677 0.323 0.000
A34 Obstetrical tetanus
0.677 0.323 0.000
A33 Tetanus neonatorum
0.677 0.323 0.000
N18.2 Chronic kidney disease, stage 2
0.676 0.324 0.000
B37 Candidiasis
0.676 0.324 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.676 0.324 0.000
F70-F79 Mental retardation
0.676 0.324 0.000
O72.1 Other immediate postpartum haemorrhage
0.676 0.324 0.000
H36 Retinal disorders in diseases classified elsewhere
0.675 0.324 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.675 0.325 0.000
L03.3 Cellulitis of trunk
0.675 0.325 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.674 0.326 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.672 0.328 0.000
R68 Other general symptoms and signs
0.671 0.329 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.671 0.329 0.000
R62 Lack of expected normal physiological development
0.671 0.329 0.000
R64 Cachexia
0.671 0.329 0.000
R58 Haemorrhage, not elsewhere classified
0.671 0.329 0.000
Z50.5 Speech therapy
0.670 0.330 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.670 0.330 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.670 0.330 0.000
I60 Subarachnoid haemorrhage
0.670 0.330 0.000
Z45 Adjustment and management of implanted device
0.670 0.330 0.000
I05-I09 Chronic rheumatic heart diseases
0.670 0.330 0.000
Z48 Other surgical follow-up care
0.669 0.331 0.000
N18.3 Chronic kidney disease, stage 3
0.668 0.332 0.000
E11.4 With neurological complications
0.668 0.332 0.000
M54.12 Radiculopathy (Cervical region)
0.667 0.333 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.667 0.333 0.000
M40-M43 Deforming dorsopathies
0.667 0.333 0.000
Z51 Other medical care
0.667 0.333 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.666 0.334 0.000
L29 Pruritus
0.666 0.334 0.000
N88.2 Stricture and stenosis of cervix uteri
0.666 0.334 0.000
Z43.2 Attention to ileostomy
0.665 0.335 0.000
N89 Other noninflammatory disorders of vagina
0.665 0.335 0.000
F48 Other neurotic disorders
0.665 0.335 0.000
F44 Dissociative [conversion] disorders
0.665 0.335 0.000
F42 Obsessive-compulsive disorder
0.665 0.335 0.000
E13 Other specified diabetes mellitus
0.665 0.335 0.000
E12 Malnutrition-related diabetes mellitus
0.665 0.335 0.000
Z41 Procedures for purposes other than remedying health state
0.665 0.335 0.000
H18 Other disorders of cornea
0.664 0.336 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.664 0.336 0.000
R04.0 Epistaxis
0.663 0.337 0.000
M19 Other arthrosis
0.663 0.337 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.662 0.338 0.000
H31 Other disorders of choroid
0.662 0.338 0.000
H30 Chorioretinal inflammation
0.662 0.338 0.000
L28 Lichen simplex chronicus and prurigo
0.661 0.339 0.000
D69 Purpura and other haemorrhagic conditions
0.661 0.339 0.000
R52.2 Other chronic pain
0.660 0.339 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.660 0.340 0.000
N18.0 End-stage renal disease
0.660 0.340 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.660 0.340 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.660 0.340 0.000
N18.8 Other chronic renal failure
0.660 0.340 0.000
N18.1 Chronic kidney disease, stage 1
0.660 0.340 0.000
X60-X84 Intentional self-harm
0.659 0.341 0.000
R25 Abnormal involuntary movements
0.659 0.341 0.000
M65.3 Trigger finger
0.659 0.341 0.000
O74 Complications of anaesthesia during labour and delivery
0.659 0.341 0.000
O73 Retained placenta and membranes, without haemorrhage
0.659 0.341 0.000
O71 Other obstetric trauma
0.659 0.341 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.659 0.341 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.659 0.341 0.000
O66 Other obstructed labour
0.659 0.341 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.659 0.341 0.000
O60 Preterm delivery
0.659 0.341 0.000
Z22 Carrier of infectious disease
0.658 0.341 0.000
H80-H83 Diseases of inner ear
0.658 0.342 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.658 0.342 0.000
E87.4 Mixed disorder of acid-base balance
0.658 0.342 0.000
E87.3 Alkalosis
0.658 0.342 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.658 0.342 0.000
E87.5 Hyperkalaemia
0.657 0.343 0.000
M14 Arthropathies in other diseases classified elsewhere
0.657 0.343 0.000
M12 Other specific arthropathies
0.657 0.343 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.657 0.343 0.000
M08 Juvenile arthritis
0.657 0.343 0.000
M05 Seropositive rheumatoid arthritis
0.657 0.343 0.000
H43.1 Vitreous haemorrhage
0.656 0.344 0.000
L03.1 Cellulitis of other parts of limb
0.655 0.345 0.000
R04.2 Haemoptysis
0.654 0.346 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.653 0.347 0.000
Y40 Systemic antibiotics
0.653 0.347 0.000
M07 Psoriatic and enteropathic arthropathies
0.652 0.347 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.653 0.347 0.000
L73 Other follicular disorders
0.651 0.349 0.000
A00-A09 Intestinal infectious diseases
0.650 0.350 0.000
H35.0 Background retinopathy and retinal vascular changes
0.650 0.350 0.000
I49 Other cardiac arrhythmias
0.649 0.351 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.648 0.352 0.000
R61 Hyperhidrosis
0.648 0.352 0.000
M20.2 Hallux rigidus
0.648 0.352 0.000
H51 Other disorders of binocular movement
0.646 0.353 0.000
H50 Other strabismus
0.646 0.353 0.000
H49 Paralytic strabismus
0.646 0.353 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.646 0.353 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.646 0.354 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.646 0.354 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.646 0.354 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.646 0.354 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.646 0.354 0.000
R16.0 Hepatomegaly, not elsewhere classified
0.645 0.355 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.645 0.355 0.000
N10-N16 Renal tubulo-interstitial diseases
0.645 0.355 0.000
L05 Pilonidal cyst
0.644 0.355 0.000
L04 Acute lymphadenitis
0.644 0.355 0.000
L01 Impetigo
0.644 0.355 0.000
L00 Staphylococcal scalded skin syndrome
0.644 0.355 0.000
I28 Other diseases of pulmonary vessels
0.644 0.356 0.000
F45 Somatoform disorders
0.644 0.356 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.643 0.357 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.642 0.358 0.000
O15 Eclampsia
0.641 0.359 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.641 0.359 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.641 0.359 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.641 0.359 0.000
R57.0 Cardiogenic shock
0.640 0.360 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.640 0.360 0.000
N20-N23 Urolithiasis
0.640 0.360 0.000
E11.8 With unspecified complications
0.639 0.360 0.000
E11.7 With multiple complications
0.639 0.360 0.000
E11.6 With other specified complications
0.639 0.360 0.000
E11.2 With renal complications
0.639 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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