TreeWAS – Variant ID: rs972540

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M25.77 Osteophyte (Ankle and foot)	0.069	0.931	0.000
M25.7 Osteophyte	0.069	0.931	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.066	0.934	0.000
M25.71 Osteophyte (Shoulder region)	0.062	0.938	0.000
M25.76 Osteophyte (Lower leg)	0.061	0.939	0.000
M25.78 Osteophyte (Other)	0.056	0.944	0.000
M25.73 Osteophyte (Forearm)	0.054	0.946	0.000
M25.74 Osteophyte (Hand)	0.051	0.949	0.000
M25.70 Osteophyte (Multiple sites)	0.050	0.950	0.000
M25.72 Osteophyte (Upper arm)	0.049	0.951	0.000
M25.79 Osteophyte (Site unspecified)	0.046	0.954	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.970	0.030
T92.1 Sequelae of fracture of arm	0.000	0.975	0.025
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.976	0.024
T92 Sequelae of injuries of upper limb	0.000	0.977	0.023
T92.9 Sequelae of unspecified injury of upper limb	0.000	0.978	0.022
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.978	0.022
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.979	0.021
T39.1 4-Aminophenol derivatives	0.000	0.981	0.019
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.000	0.981	0.019
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.981	0.019
T39.0 Salicylates	0.000	0.982	0.018
M25 Other joint disorders, not elsewhere classified	0.018	0.982	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.000	0.982	0.018
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.982	0.018
M25.6 Stiffness of joint, not elsewhere classified	0.017	0.983	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.983	0.017
T39.2 Pyrazolone derivatives	0.000	0.983	0.017
T92.0 Sequelae of open wound of upper limb	0.000	0.984	0.016
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.016	0.984	0.000
H50.9 Strabismus, unspecified	0.000	0.984	0.016
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.015	0.985	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.015	0.985	0.000
M25.3 Other instability of joint	0.015	0.985	0.000
M25.9 Joint disorder, unspecified	0.014	0.986	0.000
M25.0 Haemarthrosis	0.014	0.986	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.014	0.986	0.000
M25.33 Other instability of joint (Forearm)	0.013	0.986	0.000
M25.2 Flail joint	0.013	0.986	0.000
M25.1 Fistula of joint	0.013	0.986	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.000	0.987	0.013
M25.34 Other instability of joint (Hand)	0.013	0.987	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.012	0.987	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.012	0.987	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.987	0.012
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.012	0.988	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.012	0.988	0.000
R47.1 Dysarthria and anarthria	0.000	0.988	0.012
M25.90 Joint disorder, unspecified (Multiple sites)	0.011	0.989	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.011	0.989	0.000
M25.31 Other instability of joint (Shoulder region)	0.011	0.989	0.000
M25.39 Other instability of joint (Site unspecified)	0.011	0.989	0.000
M25.38 Other instability of joint (Other)	0.011	0.989	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.011	0.989	0.000
M25.32 Other instability of joint (Upper arm)	0.011	0.989	0.000
M25.30 Other instability of joint (Multiple sites)	0.011	0.989	0.000
R47 Speech disturbances, not elsewhere classified	0.000	0.989	0.011
M25.94 Joint disorder, unspecified (Hand)	0.010	0.989	0.000
M25.37 Other instability of joint (Ankle and foot)	0.010	0.989	0.000
M25.06 Haemarthrosis (Lower leg)	0.010	0.990	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.010	0.990	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.010	0.990	0.000
M25.98 Joint disorder, unspecified (Other)	0.010	0.990	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.010	0.990	0.000
M25.09 Haemarthrosis (Site unspecified)	0.010	0.990	0.000
M25.08 Haemarthrosis (Other)	0.010	0.990	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.010	0.990	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.010	0.990	0.000
M25.04 Haemarthrosis (Hand)	0.010	0.990	0.000
M25.03 Haemarthrosis (Forearm)	0.010	0.990	0.000
M25.02 Haemarthrosis (Upper arm)	0.010	0.990	0.000
M25.01 Haemarthrosis (Shoulder region)	0.010	0.990	0.000
M25.00 Haemarthrosis (Multiple sites)	0.010	0.990	0.000
M25.19 Fistula of joint (Site unspecified)	0.010	0.990	0.000
M25.18 Fistula of joint (Other)	0.010	0.990	0.000
M25.17 Fistula of joint (Ankle and foot)	0.010	0.990	0.000
M25.16 Fistula of joint (Lower leg)	0.010	0.990	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.010	0.990	0.000
M25.14 Fistula of joint (Hand)	0.010	0.990	0.000
M25.13 Fistula of joint (Forearm)	0.010	0.990	0.000
M25.12 Fistula of joint (Upper arm)	0.010	0.990	0.000
M25.11 Fistula of joint (Shoulder region)	0.010	0.990	0.000
M25.10 Fistula of joint (Multiple sites)	0.010	0.990	0.000
M25.29 Flail joint (Site unspecified)	0.010	0.990	0.000
M25.28 Flail joint (Other)	0.010	0.990	0.000
M25.27 Flail joint (Ankle and foot)	0.010	0.990	0.000
M25.26 Flail joint (Lower leg)	0.010	0.990	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.010	0.990	0.000
M25.24 Flail joint (Hand)	0.010	0.990	0.000
M25.23 Flail joint (Forearm)	0.010	0.990	0.000
M25.22 Flail joint (Upper arm)	0.010	0.990	0.000
M25.21 Flail joint (Shoulder region)	0.010	0.990	0.000
M25.20 Flail joint (Multiple sites)	0.010	0.990	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.990	0.010
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.990	0.010
M25.91 Joint disorder, unspecified (Shoulder region)	0.009	0.990	0.000
M25.4 Effusion of joint	0.010	0.990	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.009	0.991	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.009	0.991	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.009	0.991	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.009	0.991	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.991	0.009
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.991	0.009
M25.53 Pain in joint (Forearm)	0.009	0.991	0.000
M25.47 Effusion of joint (Ankle and foot)	0.008	0.992	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.992	0.008
M25.44 Effusion of joint (Hand)	0.008	0.992	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.992	0.008
R47.0 Dysphasia and aphasia	0.000	0.992	0.008
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.008	0.992	0.000
F10.3 Withdrawal state	0.000	0.992	0.008
M25.36 Other instability of joint (Lower leg)	0.008	0.992	0.000
T46.1 Calcium-channel blockers	0.000	0.992	0.008
R68.0 Hypothermia, not associated with low environmental temperature	0.008	0.992	0.000
T36 Poisoning by systemic antibiotics	0.000	0.992	0.008
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.000	0.992	0.008
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.992	0.008
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.992	0.008
M24.0 Loose body in joint	0.008	0.992	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.993	0.007
Y95 Nosocomial condition	0.007	0.993	0.000
M25.42 Effusion of joint (Upper arm)	0.007	0.993	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.993	0.007
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.993	0.007
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.993	0.007
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.993	0.007
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.993	0.007
T46.7 Peripheral vasodilators	0.000	0.993	0.007
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.993	0.007
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.993	0.007
M25.49 Effusion of joint (Site unspecified)	0.007	0.993	0.000
M25.48 Effusion of joint (Other)	0.007	0.993	0.000
M24.02 Loose body in joint (Upper arm)	0.007	0.993	0.000
M25.43 Effusion of joint (Forearm)	0.007	0.993	0.000
T50.8 Diagnostic agents	0.000	0.993	0.007
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.993	0.007
T50.4 Drugs affecting uric acid metabolism	0.000	0.993	0.007
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.993	0.007
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.993	0.007
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.993	0.007
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.007	0.993	0.000
M25.41 Effusion of joint (Shoulder region)	0.007	0.993	0.000
M24.03 Loose body in joint (Forearm)	0.007	0.993	0.000
R25.1 Tremor, unspecified	0.000	0.993	0.007
M24.07 Loose body in joint (Ankle and foot)	0.007	0.993	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.993	0.007
T50.7 Analeptics and opioid receptor antagonists	0.000	0.993	0.006
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.993	0.006
T50.5 Appetite depressants	0.000	0.993	0.006
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.993	0.006
T50.1 Loop [high-ceiling] diuretics	0.000	0.993	0.006
T50.0 Mineralocorticoids and their antagonists	0.000	0.993	0.006
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.993	0.007
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.994	0.006
T36.0 Penicillins	0.000	0.994	0.006
M25.40 Effusion of joint (Multiple sites)	0.006	0.994	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.994	0.006
M24.8 Other specific joint derangements, not elsewhere classified	0.006	0.994	0.000
M24.01 Loose body in joint (Shoulder region)	0.006	0.994	0.000
M25.5 Pain in joint	0.006	0.994	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.994	0.006
M24.04 Loose body in joint (Hand)	0.006	0.994	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.994	0.006
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.994	0.006
T47.7 Emetics	0.000	0.994	0.006
T47.6 Antidiarrhoeal drugs	0.000	0.994	0.006
T47.5 Digestants	0.000	0.994	0.006
T47.4 Other laxatives	0.000	0.994	0.006
T47.3 Saline and osmotic laxatives	0.000	0.994	0.006
T47.2 Stimulant laxatives	0.000	0.994	0.006
T47.0 Histamine H(2)-receptor antagonists	0.000	0.994	0.006
M24.06 Loose body in joint-Lower leg	0.006	0.994	0.000
C15.5 Lower third of oesophagus	0.006	0.994	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.994	0.006
T36.8 Other systemic antibiotics	0.000	0.994	0.006
T36.7 Antifungal antibiotics, systemically used	0.000	0.994	0.006
T36.6 Rifamycins	0.000	0.994	0.006
T36.5 Aminoglycosides	0.000	0.994	0.006
T36.4 Tetracyclines	0.000	0.994	0.006
T36.3 Macrolides	0.000	0.994	0.006
T36.2 Chloramphenicol group	0.000	0.994	0.006
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.994	0.006
M24 Other specific joint derangements	0.006	0.994	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.994	0.006
T37.5 Antiviral drugs	0.000	0.994	0.006
T37.4 Anthelminthics	0.000	0.994	0.006
T37.3 Other antiprotozoal drugs	0.000	0.994	0.006
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.994	0.006
T37.1 Antimycobacterial drugs	0.000	0.994	0.006
T37.0 Sulphonamides	0.000	0.994	0.006
C15.9 Oesophagus, unspecified	0.006	0.994	0.000
T40.4 Other synthetic narcotics	0.000	0.994	0.006
M24.09 Loose body in joint (Site unspecified)	0.006	0.994	0.000
M24.08 Loose body in joint (Other)	0.006	0.994	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.006	0.994	0.000
M24.00 Loose body in joint (Multiple sites)	0.006	0.994	0.000
M25.52 Pain in joint (Upper arm)	0.006	0.994	0.000
T40.2 Other opioids	0.000	0.994	0.006
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.005	0.994	0.000
T41.5 Therapeutic gases	0.000	0.995	0.005
T41.4 Anaesthetic, unspecified	0.000	0.995	0.005
T41.3 Local anaesthetics	0.000	0.995	0.005
T41.2 Other and unspecified general anaesthetics	0.000	0.995	0.005
T41.1 Intravenous anaesthetics	0.000	0.995	0.005
T41.0 Inhaled anaesthetics	0.000	0.995	0.005
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.995	0.005
T45.0 Antiallergic and antiemetic drugs	0.000	0.995	0.005
Z51.4 Preparatory care for treatment, not elsewhere classified	0.005	0.995	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.005	0.995	0.000
M25.54 Pain in joint (Hand)	0.005	0.995	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.005	0.995	0.000
C15 Malignant neoplasm of oesophagus	0.005	0.995	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.995	0.005
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.995	0.005
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.995	0.005
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.995	0.005
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.995	0.005
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.995	0.005
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.995	0.005
T44.0 Anticholinesterase agents	0.000	0.995	0.005
T49.9 Topical agent, unspecified	0.000	0.995	0.005
T49.8 Other topical agents	0.000	0.995	0.005
T49.7 Dental drugs, topically applied	0.000	0.995	0.005
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.995	0.005
T49.5 Ophthalmological drugs and preparations	0.000	0.995	0.005
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.995	0.005
T49.3 Emollients, demulcents and protectants	0.000	0.995	0.005
T49.2 Local astringents and local detergents	0.000	0.995	0.005
T49.1 Antipruritics	0.000	0.995	0.005
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.995	0.005
T40.8 Lysergide [LSD]	0.000	0.995	0.005
T40.7 Cannabis (derivatives)	0.000	0.995	0.005
T40.3 Methadone	0.000	0.995	0.005
T40.1 Heroin	0.000	0.995	0.005
T40.0 Opium	0.000	0.995	0.005
M25.58 Pain in joint (Other)	0.005	0.995	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.995	0.005
M24.5 Contracture of joint	0.005	0.995	0.000
Q61.0 Congenital single renal cyst	0.005	0.995	0.000
Q61.2 Polycystic kidney, adult type	0.005	0.995	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.005	0.995	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.005	0.995	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.995	0.005
T45.8 Other primarily systemic and haematological agents	0.000	0.995	0.005
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.995	0.005
T45.6 Fibrinolysis-affecting drugs	0.000	0.995	0.005
T45.4 Iron and its compounds	0.000	0.995	0.005
T45.3 Enzymes, not elsewhere classified	0.000	0.995	0.005
C15.3 Upper third of oesophagus	0.005	0.995	0.000
M19.1 Posttraumatic arthrosis of other joints	0.005	0.995	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.995	0.005
T48.5 Anti-common-cold drugs	0.000	0.995	0.005
T48.4 Expectorants	0.000	0.995	0.005
T48.3 Antitussives	0.000	0.995	0.005
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.995	0.005
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.995	0.005
T48.0 Oxytocic drugs	0.000	0.995	0.005
Z88.3 Personal history of allergy to other anti-infective agents	0.005	0.995	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.005	0.995	0.000
T45.2 Vitamins, not elsewhere classified	0.000	0.995	0.005
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.005	0.995	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.005	0.995	0.000
T40.5 Cocaine	0.000	0.995	0.005
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.995	0.005
M25.45 Effusion of joint (Pelvic region and thigh)	0.005	0.995	0.000
H90.5 Sensorineural hearing loss, unspecified	0.005	0.995	0.000
M24.9 Joint derangement, unspecified	0.005	0.995	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.005	0.995	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
M24.57 Contracture of joint (Ankle and foot)	0.005	0.995	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.995	0.005
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
M25.8 Other specified joint disorders	0.004	0.995	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.005	0.995	0.000
T45.5 Anticoagulants	0.000	0.995	0.004
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.004	0.995	0.000
R29.6 Tendency to fall, not elsewhere classified	0.005	0.995	0.000
Q61 Cystic kidney disease	0.005	0.995	0.000
M24.54 Contracture of joint (Hand)	0.004	0.995	0.000
I05.0 Mitral stenosis	0.000	0.995	0.004
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.996	0.004
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.996	0.004
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.004	0.996	0.000
M24.7 Protrusio acetabuli	0.004	0.996	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.996	0.004
O81.4 Vacuum extractor delivery	0.004	0.996	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.996	0.004
M24.52 Contracture of joint (Upper arm)	0.004	0.996	0.000
M24.1 Other articular cartilage disorders	0.004	0.996	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.004	0.996	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.004	0.996	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.004	0.996	0.000
C15.0 Cervical part of oesophagus	0.004	0.996	0.000
F10.0 Acute intoxication	0.000	0.996	0.004
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.004	0.996	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.004	0.996	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.004	0.996	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.004	0.996	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.004	0.996	0.000
C15.8 Overlapping lesion of oesophagus	0.004	0.996	0.000
C15.2 Abdominal part of oesophagus	0.004	0.996	0.000
C15.1 Thoracic part of oesophagus	0.004	0.996	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.996	0.004
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.996	0.004
M24.96 Joint derangement, unspecified (Lower leg)	0.004	0.996	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.996	0.004
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.996	0.004
M24.51 Contracture of joint (Shoulder region)	0.004	0.996	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.996	0.004
T38.7 Androgens and anabolic congeners	0.000	0.996	0.004
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.996	0.004
T38.5 Other oestrogens and progestogens	0.000	0.996	0.004
T38.4 Oral contraceptives	0.000	0.996	0.004
T38.2 Antithyroid drugs	0.000	0.996	0.004
T38.0 Glucocorticoids and synthetic analogues	0.000	0.996	0.004
M24.59 Contracture of joint (Site unspecified)	0.004	0.996	0.000
M24.58 Contracture of joint (Other)	0.004	0.996	0.000
M24.53 Contracture of joint (Forearm)	0.004	0.996	0.000
M24.50 Contracture of joint (Multiple sites)	0.004	0.996	0.000
M25.84 Other specified joint disorders (Hand)	0.004	0.996	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.996	0.004
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.996	0.004
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.004	0.996	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.004	0.996	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.004	0.996	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.004	0.996	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.004	0.996	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.004	0.996	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.000	0.996	0.004
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.996	0.003
M24.99 Joint derangement, unspecified (Site unspecified)	0.004	0.996	0.000
M24.98 Joint derangement, unspecified (Other)	0.004	0.996	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.004	0.996	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M24.94 Joint derangement, unspecified (Hand)	0.004	0.996	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.004	0.996	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.004	0.996	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.004	0.996	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.004	0.996	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.996	0.004
R47-R49 Symptoms and signs involving speech and voice	0.000	0.996	0.004
T40.6 Other and unspecified narcotics	0.000	0.996	0.003
M24.13 Other articular cartilage disorders (Forearm)	0.004	0.996	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.003	0.996	0.000
I84.3 External thrombosed haemorrhoids	0.004	0.996	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.003	0.996	0.000
M25.82 Other specified joint disorders (Upper arm)	0.003	0.996	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.003	0.996	0.000
F10.4 Withdrawal state with delirium	0.000	0.996	0.004
Q61.3 Polycystic kidney, unspecified	0.004	0.996	0.000
Q61.8 Other cystic kidney diseases	0.003	0.996	0.000
Q61.4 Renal dysplasia	0.003	0.996	0.000
Q61.1 Polycystic kidney, infantile type	0.003	0.996	0.000
I05 Rheumatic mitral valve diseases	0.000	0.996	0.004
M24.6 Ankylosis of joint	0.003	0.996	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
L72.1 Trichilemmal cyst	0.003	0.997	0.000
O81 Single delivery by forceps and vacuum extractor	0.003	0.997	0.000
C15.4 Middle third of oesophagus	0.003	0.997	0.000
R68 Other general symptoms and signs	0.003	0.997	0.000
M25.50 Pain in joint (Multiple sites)	0.003	0.997	0.000
O81.0 Low forceps delivery	0.003	0.997	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.003	0.997	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.003	0.997	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.003	0.997	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
M25.83 Other specified joint disorders (Forearm)	0.003	0.997	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.003	0.997	0.000
M24.79 Protrusio acetabuli-Site unspec	0.003	0.997	0.000
M24.78 Protrusio acetabuli-Other	0.003	0.997	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.003	0.997	0.000
M24.76 Protrusio acetabuli-Lower leg	0.003	0.997	0.000
M24.74 Protrusio acetabuli-Hand	0.003	0.997	0.000
M24.73 Protrusio acetabuli-Forearm	0.003	0.997	0.000
M24.72 Protrusio acetabuli-Upper arm	0.003	0.997	0.000
M24.71 Protrusio acetabuli-Shldr region	0.003	0.997	0.000
M24.70 Protrusio acetabuli-Mult sites	0.003	0.997	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.003	0.997	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.003	0.997	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.003	0.997	0.000
Q61.9 Cystic kidney disease, unspecified	0.003	0.997	0.000
F31 Bipolar affective disorder	0.000	0.997	0.003
F10.6 Amnesic syndrome	0.000	0.997	0.003
N43.3 Hydrocele, unspecified	0.003	0.997	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.003	0.997	0.000
M24.18 Other articular cartilage disorders (Other)	0.003	0.997	0.000
M24.14 Other articular cartilage disorders (Hand)	0.003	0.997	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.003	0.997	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.003	0.997	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.997	0.003
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.997	0.003
M24.75 Protrusio acetabuli-Pelvic/thigh	0.003	0.997	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.997	0.003
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.003	0.997	0.000
M25.88 Other specified joint disorders (Other)	0.003	0.997	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.003	0.997	0.000
O81.3 Other and unspecified forceps delivery	0.003	0.997	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.003	0.997	0.000
M24.56 Contracture of joint (Lower leg)	0.003	0.997	0.000
W25.9 Unspecified place	0.003	0.997	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.003	0.997	0.000
F10.8 Other mental and behavioural disorders	0.000	0.997	0.003
F10.9 Unspecified mental and behavioural disorder	0.000	0.997	0.003
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.003	0.997	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.000	0.997	0.003
I05.1 Rheumatic mitral insufficiency	0.000	0.997	0.003
M24.11 Other articular cartilage disorders (Shoulder region)	0.003	0.997	0.000
Q61.5 Medullary cystic kidney	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.003	0.997	0.000
R68.2 Dry mouth, unspecified	0.003	0.997	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.000	0.997	0.003
M25.59 Pain in joint (Site unspecified)	0.003	0.997	0.000
F10.5 Psychotic disorder	0.000	0.997	0.003
M24.2 Disorder of ligament	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.997	0.003
I05.8 Other mitral valve diseases	0.000	0.997	0.003
M24.69 Ankylosis of joint (Site unspecified)	0.003	0.997	0.000
M24.68 Ankylosis of joint (Other)	0.003	0.997	0.000
M24.64 Ankylosis of joint (Hand)	0.003	0.997	0.000
M24.63 Ankylosis of joint (Forearm)	0.003	0.997	0.000
M24.62 Ankylosis of joint (Upper arm)	0.003	0.997	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.003	0.997	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.003	0.997	0.000
F10.7 Residual and late-onset psychotic disorder	0.000	0.997	0.003
R68.8 Other specified general symptoms and signs	0.003	0.997	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.003	0.997	0.000
O81.2 Mid-cavity forceps with rotation	0.003	0.997	0.000
O81.1 Mid-cavity forceps delivery	0.003	0.997	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.002	0.997	0.000
R68.1 Nonspecific symptoms peculiar to infancy	0.003	0.997	0.000
S00.0 Superficial injury of scalp	0.000	0.997	0.003
B07 Viral warts	0.003	0.997	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.003	0.997	0.000
C44.1 Skin of eyelid, including canthus	0.000	0.997	0.003
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.003	0.997	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.003	0.997	0.000
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.997	0.003
Q62.2 Congenital megaloureter	0.003	0.997	0.000
M25.57 Pain in joint (Ankle and foot)	0.003	0.997	0.000
C02.9 Tongue, unspecified	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.000	0.997	0.002
Q64.4 Malformation of urachus	0.002	0.997	0.000
Y98 Lifestyle-related condition	0.002	0.997	0.000
Y97 Environmental-pollution-related condition	0.002	0.997	0.000
Y96 Work-related condition	0.002	0.997	0.000
C43.5 Malignant melanoma of trunk	0.003	0.997	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.002	0.997	0.000
M24.23 Disorder of ligament (Forearm)	0.002	0.998	0.000
R68.3 Clubbing of fingers	0.002	0.998	0.000
M24.66 Ankylosis of joint (Lower leg)	0.002	0.998	0.000
L30.8 Other specified dermatitis	0.000	0.998	0.002
Z90.2 Acquired absence of lung [part of]	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
M24.28 Disorder of ligament (Other)	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.998	0.002
M24.67 Ankylosis of joint (Ankle and foot)	0.002	0.998	0.000
H50.4 Other and unspecified heterotropia	0.000	0.998	0.002
Q62.7 Congenital vesico-uretero-renal reflux	0.002	0.998	0.000
Q62.6 Malposition of ureter	0.002	0.998	0.000
Q62.4 Agenesis of ureter	0.002	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.002	0.998	0.000
Q62.1 Atresia and stenosis of ureter	0.002	0.998	0.000
Q62.0 Congenital hydronephrosis	0.002	0.998	0.000
R48.8 Other and unspecified symbolic dysfunctions	0.000	0.998	0.002
R48.2 Apraxia	0.000	0.998	0.002
R48.1 Agnosia	0.000	0.998	0.002
R48.0 Dyslexia and alexia	0.000	0.998	0.002
R49.8 Other and unspecified voice disturbances	0.000	0.998	0.002
Y90.8 Blood alcohol level of 240 mg/100 ml or more	0.002	0.998	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.002	0.998	0.000
M24.29 Disorder of ligament (Site unspecified)	0.002	0.998	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.002	0.998	0.000
M24.22 Disorder of ligament (Upper arm)	0.002	0.998	0.000
M24.20 Disorder of ligament (Multiple sites)	0.002	0.998	0.000
Q62.5 Duplication of ureter	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.998	0.002
M25.87 Other specified joint disorders (Ankle and foot)	0.002	0.998	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.998	0.000
C78.2 Secondary malignant neoplasm of pleura	0.002	0.998	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.002	0.998	0.000
R49 Voice disturbances	0.000	0.998	0.002
K10.8 Other specified diseases of jaws	0.002	0.998	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations