TreeWAS – Variant ID: rs9841616

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.024	0.976	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.018	0.982	0.000
I78.1 Naevus, nonneoplastic	0.000	0.984	0.016
D51 Vitamin B12 deficiency anaemia	0.015	0.985	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.014	0.986	0.000
H25.9 Senile cataract, unspecified	0.000	0.987	0.013
S82.40 Fracture of fibula alone (closed)	0.013	0.987	0.000
M84.0 Malunion of fracture	0.012	0.988	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.011	0.989	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.011	0.989	0.000
D51.2 Transcobalamin II deficiency	0.011	0.989	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.011	0.989	0.000
D50-D53 Nutritional anaemias	0.011	0.989	0.000
M84.03 Malunion of fracture (Forearm)	0.011	0.989	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.010	0.990	0.000
M84.06 Malunion of fracture (Lower leg)	0.010	0.990	0.000
D52 Folate deficiency anaemia	0.010	0.990	0.000
M84.04 Malunion of fracture (Hand)	0.010	0.990	0.000
D52.9 Folate deficiency anaemia, unspecified	0.010	0.990	0.000
M35.3 Polymyalgia rheumatica	0.000	0.990	0.010
I78 Diseases of capillaries	0.000	0.990	0.010
M84.05 Malunion of fracture (Pelvic region and thigh)	0.009	0.991	0.000
M84.01 Malunion of fracture (Shoulder region)	0.009	0.991	0.000
M84.02 Malunion of fracture (Upper arm)	0.009	0.991	0.000
D53 Other nutritional anaemias	0.009	0.991	0.000
M84.09 Malunion of fracture (Site unspecified)	0.008	0.991	0.000
M84.08 Malunion of fracture (Other)	0.008	0.991	0.000
M84.00 Malunion of fracture (Multiple sites)	0.008	0.991	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.992	0.008
D52.8 Other folate deficiency anaemias	0.007	0.992	0.000
D52.1 Drug-induced folate deficiency anaemia	0.007	0.992	0.000
D52.0 Dietary folate deficiency anaemia	0.007	0.992	0.000
J35.0 Chronic tonsillitis	0.007	0.993	0.000
I78.8 Other diseases of capillaries	0.000	0.993	0.007
D53.9 Nutritional anaemia, unspecified	0.007	0.993	0.000
M84 Disorders of continuity of bone	0.007	0.993	0.000
I78.9 Disease of capillaries, unspecified	0.000	0.993	0.007
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.007	0.993	0.000
M31.6 Other giant cell arteritis	0.000	0.993	0.007
D53.8 Other specified nutritional anaemias	0.006	0.993	0.000
D53.2 Scorbutic anaemia	0.006	0.993	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.006	0.993	0.000
D53.0 Protein deficiency anaemia	0.006	0.993	0.000
J30.1 Allergic rhinitis due to pollen	0.006	0.994	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.006	0.994	0.000
M84.8 Other disorders of continuity of bone	0.006	0.994	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.006	0.994	0.000
M84.3 Stress fracture, not elsewhere classified	0.006	0.994	0.000
J34.3 Hypertrophy of nasal turbinates	0.006	0.994	0.000
S82.4 Fracture of fibula alone	0.006	0.994	0.000
D63.0 Anaemia in neoplastic disease	0.006	0.994	0.000
D50 Iron deficiency anaemia	0.006	0.994	0.000
M84.9 Disorder of continuity of bone, unspecified	0.005	0.994	0.000
M84.2 Delayed union of fracture	0.005	0.994	0.000
D50.8 Other iron deficiency anaemias	0.005	0.995	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.005	0.995	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
J06.9 Acute upper respiratory infection, unspecified	0.000	0.995	0.005
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.995	0.005
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.005	0.995	0.000
G93.9 Disorder of brain, unspecified	0.000	0.995	0.005
M25.77 Osteophyte (Ankle and foot)	0.005	0.995	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.005	0.995	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.005	0.995	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.005	0.995	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.005	0.995	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.005	0.995	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.005	0.995	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.005	0.995	0.000
M84.88 Other disorders of continuity of bone (Other)	0.005	0.995	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.005	0.995	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.005	0.995	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.005	0.995	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.005	0.995	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.005	0.995	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.005	0.995	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.005	0.995	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.005	0.995	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.005	0.995	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.005	0.995	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.005	0.995	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.005	0.995	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
C01 Malignant neoplasm of base of tongue	0.005	0.995	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.005	0.995	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.004	0.996	0.000
S82.41 Fracture of fibula alone (open)	0.004	0.996	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.004	0.996	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.004	0.996	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.004	0.996	0.000
M84.28 Delayed union of fracture (Other)	0.004	0.996	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.004	0.996	0.000
M84.26 Delayed union of fracture (Lower leg)	0.004	0.996	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.004	0.996	0.000
M84.24 Delayed union of fracture (Hand)	0.004	0.996	0.000
M84.23 Delayed union of fracture (Forearm)	0.004	0.996	0.000
M84.22 Delayed union of fracture (Upper arm)	0.004	0.996	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.004	0.996	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.004	0.996	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.004	0.996	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.004	0.996	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.004	0.996	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.004	0.996	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.004	0.996	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.004	0.996	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.004	0.996	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.004	0.996	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.004	0.996	0.000
D50.1 Sideropenic dysphagia	0.004	0.996	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.000	0.996	0.004
Z71.1 Person with feared complaint in whom no diagnosis is made	0.004	0.996	0.000
M84.4 Pathological fracture, not elsewhere classified	0.004	0.996	0.001
C06 Malignant neoplasm of other and unspecified parts of mouth	0.004	0.996	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.004	0.996	0.000
C10 Malignant neoplasm of oropharynx	0.004	0.996	0.000
J35 Chronic diseases of tonsils and adenoids	0.004	0.996	0.000
C06.0 Cheek mucosa	0.004	0.996	0.000
J38.0 Paralysis of vocal cords and larynx	0.004	0.996	0.000
D60-D64 Aplastic and other anaemias	0.004	0.996	0.000
C10.9 Oropharynx, unspecified	0.004	0.996	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.996	0.004
D80 Immunodeficiency with predominantly antibody defects	0.004	0.996	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.004	0.996	0.000
C11 Malignant neoplasm of nasopharynx	0.004	0.996	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.004	0.996	0.000
C05 Malignant neoplasm of palate	0.004	0.996	0.000
D80-D89 Certain disorders involving the immune mechanism	0.004	0.996	0.000
C12 Malignant neoplasm of pyriform sinus	0.004	0.996	0.000
S42.30 Fracture of shaft of humerus (closed)	0.004	0.996	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.004	0.996	0.000
C13 Malignant neoplasm of hypopharynx	0.004	0.996	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.004	0.996	0.000
C00 Malignant neoplasm of lip	0.004	0.996	0.000
J80 Adult respiratory distress syndrome	0.004	0.996	0.000
Q60.0 Renal agenesis, unilateral	0.004	0.996	0.000
C11.9 Nasopharynx, unspecified	0.003	0.996	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.003	0.996	0.000
D84 Other immunodeficiencies	0.003	0.996	0.000
L84 Corns and callosities	0.000	0.997	0.003
E11.9 Without complications	0.003	0.997	0.000
C03 Malignant neoplasm of gum	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
C06.9 Mouth, unspecified	0.003	0.997	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.003	0.997	0.000
C04 Malignant neoplasm of floor of mouth	0.003	0.997	0.000
D62 Acute posthaemorrhagic anaemia	0.003	0.997	0.000
Z48.0 Attention to surgical dressings and sutures	0.003	0.997	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.003	0.997	0.000
C05.0 Hard palate	0.003	0.997	0.000
D84.9 Immunodeficiency, unspecified	0.003	0.997	0.000
H00.1 Chalazion	0.003	0.997	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.997	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.003	0.997	0.001
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.003	0.997	0.001
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.003	0.997	0.001
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.003	0.997	0.001
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.003	0.997	0.001
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.003	0.997	0.001
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.003	0.997	0.001
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.003	0.997	0.001
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.003	0.997	0.000
C06.2 Retromolar area	0.003	0.997	0.000
C06.1 Vestibule of mouth	0.003	0.997	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.003	0.997	0.000
J35.1 Hypertrophy of tonsils	0.003	0.997	0.000
D04.7 Skin of lower limb, including hip	0.000	0.997	0.003
C05.9 Palate, unspecified	0.003	0.997	0.000
C10.8 Overlapping lesion of oropharynx	0.003	0.997	0.000
C10.4 Branchial cleft	0.003	0.997	0.000
C10.3 Posterior wall of oropharynx	0.003	0.997	0.000
C10.2 Lateral wall of oropharynx	0.003	0.997	0.000
C10.1 Anterior surface of epiglottis	0.003	0.997	0.000
C10.0 Vallecula	0.003	0.997	0.000
C09 Malignant neoplasm of tonsil	0.003	0.997	0.000
C13.9 Hypopharynx, unspecified	0.003	0.997	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.003	0.997	0.000
C08.9 Major salivary gland, unspecified	0.003	0.997	0.000
C00.0 External upper lip	0.003	0.997	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.003	0.997	0.000
E05.8 Other thyrotoxicosis	0.003	0.997	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.003	0.997	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.001
C02.4 Lingual tonsil	0.003	0.997	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.003	0.997	0.000
C11.8 Overlapping lesion of nasopharynx	0.003	0.997	0.000
C11.3 Anterior wall of nasopharynx	0.003	0.997	0.000
C11.2 Lateral wall of nasopharynx	0.003	0.997	0.000
C11.1 Posterior wall of nasopharynx	0.003	0.997	0.000
C11.0 Superior wall of nasopharynx	0.003	0.997	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.003	0.997	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.003	0.997	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.003	0.997	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.003	0.997	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.003	0.997	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.003	0.997	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.003	0.997	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.003	0.997	0.000
C07 Malignant neoplasm of parotid gland	0.003	0.997	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.003	0.997	0.000
D83 Common variable immunodeficiency	0.003	0.997	0.000
D82 Immunodeficiency associated with other major defects	0.003	0.997	0.000
D81 Combined immunodeficiencies	0.003	0.997	0.000
C05.8 Overlapping lesion of palate	0.003	0.997	0.000
C05.2 Uvula	0.003	0.997	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.003	0.997	0.000
Q61.0 Congenital single renal cyst	0.003	0.997	0.000
C04.0 Anterior floor of mouth	0.003	0.997	0.000
C08.8 Overlapping lesion of major salivary glands	0.003	0.997	0.000
C08.1 Sublingual gland	0.003	0.997	0.000
C08.0 Submandibular gland	0.003	0.997	0.000
C13.8 Overlapping lesion of hypopharynx	0.003	0.997	0.000
C13.2 Posterior wall of hypopharynx	0.003	0.997	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.003	0.997	0.000
C13.0 Postcricoid region	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.003	0.997	0.000
C00.9 Lip, unspecified	0.003	0.997	0.000
C00.8 Overlapping lesion of lip	0.003	0.997	0.000
C00.6 Commissure of lip	0.003	0.997	0.000
C00.5 Lip, unspecified, inner aspect	0.003	0.997	0.000
C00.4 Lower lip, inner aspect	0.003	0.997	0.000
C00.3 Upper lip, inner aspect	0.003	0.997	0.000
C00.2 External lip, unspecified	0.003	0.997	0.000
C00.1 External lower lip	0.003	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.997	0.000
M31 Other necrotising vasculopathies	0.000	0.997	0.003
Q61 Cystic kidney disease	0.003	0.997	0.000
D86 Sarcoidosis	0.003	0.997	0.000
D55-D59 Haemolytic anaemias	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
D84.8 Other specified immunodeficiencies	0.003	0.997	0.000
D84.1 Defects in the complement system	0.003	0.997	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.003	0.997	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.003	0.997	0.000
C03.9 Gum, unspecified	0.003	0.997	0.000
C03.1 Lower gum	0.003	0.997	0.000
C03.0 Upper gum	0.003	0.997	0.000
L57.0 Actinic keratosis	0.000	0.997	0.003
B07 Viral warts	0.003	0.997	0.000
C05.1 Soft palate	0.003	0.997	0.000
J30 Vasomotor and allergic rhinitis	0.003	0.997	0.000
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
C04.8 Overlapping lesion of floor of mouth	0.003	0.997	0.000
C04.1 Lateral floor of mouth	0.003	0.997	0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.003	0.997	0.000
C14.2 Waldeyer's ring	0.003	0.997	0.000
Q85.9 Phakomatosis, unspecified	0.003	0.997	0.000
D61 Other aplastic anaemias	0.003	0.997	0.000
C02.8 Overlapping lesion of tongue	0.003	0.997	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.003	0.997	0.000
C02.2 Ventral surface of tongue	0.003	0.997	0.000
C02.0 Dorsal surface of tongue	0.003	0.997	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.000	0.997	0.003
E05.5 Thyroid crisis or storm	0.003	0.997	0.000
E05.4 Thyrotoxicosis factitia	0.003	0.997	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.003	0.997	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.003	0.997	0.000
C02.9 Tongue, unspecified	0.003	0.997	0.000
C14.0 Pharynx, unspecified	0.002	0.997	0.000
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.003	0.997	0.000
J35.2 Hypertrophy of adenoids	0.002	0.997	0.000
L93.0 Discoid lupus erythematosus	0.000	0.997	0.003
Q85.8 Other phakomatoses, not elsewhere classified	0.003	0.997	0.000
C09.8 Overlapping lesion of tonsil	0.002	0.997	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.002	0.997	0.000
C09.0 Tonsillar fossa	0.002	0.997	0.000
M35 Other systemic involvement of connective tissue	0.000	0.997	0.003
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.000	0.997	0.003
D60.9 Acquired pure red cell aplasia, unspecified	0.002	0.997	0.000
D60.8 Other acquired pure red cell aplasias	0.002	0.997	0.000
D60.1 Transient acquired pure red cell aplasia	0.002	0.997	0.000
D60.0 Chronic acquired pure red cell aplasia	0.002	0.997	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.001	0.997	0.001
J38.7 Other diseases of larynx	0.003	0.997	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.997	0.000
Q60.6 Potter's syndrome	0.002	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.002	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.002	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.002	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
C04.9 Floor of mouth, unspecified	0.002	0.998	0.000
Q85.1 Tuberous sclerosis	0.002	0.998	0.000
M31.8 Other specified necrotising vasculopathies	0.000	0.998	0.002
M31.7 Microscopic polyangiitis	0.000	0.998	0.002
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.998	0.002
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.998	0.002
M31.2 Lethal midline granuloma	0.000	0.998	0.002
M31.1 Thrombotic microangiopathy	0.000	0.998	0.002
M31.0 Hypersensitivity angiitis	0.000	0.998	0.002
M35.7 Hypermobility syndrome	0.000	0.998	0.002
Q61.9 Cystic kidney disease, unspecified	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.002	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.998	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.002	0.998	0.000
M31.3 Wegener's granulomatosis	0.000	0.998	0.002
M35.1 Other overlap syndromes	0.000	0.998	0.002
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
X41.9 Unspecified place	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
D58.0 Hereditary spherocytosis	0.002	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
D57 Sickle-cell disorders	0.002	0.998	0.000
D55 Anaemia due to enzyme disorders	0.002	0.998	0.000
C09.9 Tonsil, unspecified	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.002	0.998	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.998	0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D61.0 Constitutional aplastic anaemia	0.002	0.998	0.000
J30.2 Other seasonal allergic rhinitis	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
I81 Portal vein thrombosis	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
D61.8 Other specified aplastic anaemias	0.002	0.998	0.000
D61.3 Idiopathic aplastic anaemia	0.002	0.998	0.000
D61.2 Aplastic anaemia due to other external agents	0.002	0.998	0.000
D61.1 Drug-induced aplastic anaemia	0.002	0.998	0.000
L89.1 Stage II decubitus ulcer	0.000	0.998	0.002
X68.9 Unspecified place	0.002	0.998	0.000
L93 Lupus erythematosus	0.000	0.998	0.002
Q83 Congenital malformations of breast	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.002	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
J06.8 Other acute upper respiratory infections of multiple sites	0.000	0.998	0.002
J06.0 Acute laryngopharyngitis	0.000	0.998	0.002
M31.9 Necrotising vasculopathy, unspecified	0.000	0.998	0.002
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
S42.3 Fracture of shaft of humerus	0.002	0.998	0.000
D56 Thalassaemia	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
Z71.8 Other specified counselling	0.002	0.998	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.002	0.998	0.000
G31.8 Other specified degenerative diseases of nervous system	0.002	0.998	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.998	0.002
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.998	0.002
M35.5 Multifocal fibrosclerosis	0.000	0.998	0.002
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.998	0.002
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
L89 Decubitus ulcer	0.000	0.998	0.002
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.002	0.998	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.002	0.998	0.000
D58.2 Other haemoglobinopathies	0.002	0.998	0.000
D58.1 Hereditary elliptocytosis	0.002	0.998	0.000
E05.9 Thyrotoxicosis, unspecified	0.002	0.998	0.000
H26.4 After-cataract	0.002	0.998	0.000
J30.0 Vasomotor rhinitis	0.002	0.998	0.000
M35.8 Other specified systemic involvement of connective tissue	0.000	0.998	0.002
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
F03 Unspecified dementia	0.002	0.998	0.000
J34 Other disorders of nose and nasal sinuses	0.002	0.998	0.000
C02.1 Border of tongue	0.002	0.998	0.000
Q38.8 Other congenital malformations of pharynx	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.998	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.998	0.000
Q64.4 Malformation of urachus	0.002	0.998	0.000
Q64.2 Congenital posterior urethral valves	0.002	0.998	0.000
Q64.1 Exstrophy of urinary bladder	0.002	0.998	0.000
Q64.0 Epispadias	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
Q82.2 Mastocytosis	0.002	0.998	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.002	0.998	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.002	0.998	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.002	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.002	0.998	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
J38.3 Other diseases of vocal cords	0.002	0.998	0.000
Q39.4 Oesophageal web	0.002	0.998	0.000
D64 Other anaemias	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
Q38.7 Pharyngeal pouch	0.002	0.998	0.000
Q62.8 Other congenital malformations of ureter	0.002	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.002	0.998	0.000
Q62.6 Malposition of ureter	0.002	0.998	0.000
Q62.5 Duplication of ureter	0.002	0.998	0.000
Q62.4 Agenesis of ureter	0.002	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.002	0.998	0.000
Q62.2 Congenital megaloureter	0.002	0.998	0.000
Q62.1 Atresia and stenosis of ureter	0.002	0.998	0.000
Q62.0 Congenital hydronephrosis	0.002	0.998	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.998	0.002
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.002	0.998	0.000
D55.8 Other anaemias due to enzyme disorders	0.002	0.998	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.002	0.998	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.002	0.998	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.002	0.998	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.002	0.998	0.000
D57.8 Other sickle-cell disorders	0.002	0.998	0.000
D57.3 Sickle-cell trait	0.002	0.998	0.000
D57.2 Double heterozygous sickling disorders	0.002	0.998	0.000
D57.1 Sickle-cell anaemia without crisis	0.002	0.998	0.000
D57.0 Sickle-cell anaemia with crisis	0.002	0.998	0.000
G31.0 Circumscribed brain atrophy	0.002	0.998	0.000
J30.3 Other allergic rhinitis	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.000	0.998	0.002
Q82.9 Congenital malformation of skin, unspecified	0.002	0.998	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.002	0.998	0.000
Q82.3 Incontinentia pigmenti	0.002	0.998	0.000
Q82.1 Xeroderma pigmentosum	0.002	0.998	0.000
Q82.0 Hereditary lymphoedema	0.002	0.998	0.000
Q83.1 Accessory breast	0.002	0.998	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.002	0.998	0.000
N45 Orchitis and epididymitis	0.002	0.998	0.000
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
J30-J39 Other diseases of upper respiratory tract	0.002	0.998	0.000
D04.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.002	0.998	0.000
Q89.8 Other specified congenital malformations	0.002	0.998	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.002	0.998	0.000
Q89.4 Conjoined twins	0.002	0.998	0.000
Q89.3 Situs inversus	0.002	0.998	0.000
Q89.1 Congenital malformations of adrenal gland	0.002	0.998	0.000
Q89.0 Congenital malformations of spleen	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
L93.2 Other local lupus erythematosus	0.000	0.998	0.002
L93.1 Subacute cutaneous lupus erythematosus	0.000	0.998	0.002
Q80.9 Congenital ichthyosis, unspecified	0.002	0.998	0.000
Q80.8 Other congenital ichthyosis	0.002	0.998	0.000
Q80.4 Harlequin foetus	0.002	0.998	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.002	0.998	0.000
Q80.2 Lamellar ichthyosis	0.002	0.998	0.000
Q80.1 X-linked ichthyosis	0.002	0.998	0.000
Q80.0 Ichthyosis vulgaris	0.002	0.998	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.002	0.998	0.000
Q81.8 Other epidermolysis bullosa	0.002	0.998	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.002	0.998	0.000
Q81.1 Epidermolysis bullosa letalis	0.002	0.998	0.000
Q81.0 Epidermolysis bullosa simplex	0.002	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.002	0.998	0.000
Q83.9 Congenital malformation of breast, unspecified	0.002	0.998	0.000
Q83.3 Accessory nipple	0.002	0.998	0.000
Q83.2 Absent nipple	0.002	0.998	0.000
Q83.0 Congenital absence of breast with absent nipple	0.002	0.998	0.000
Q84.9 Congenital malformation of integument, unspecified	0.002	0.998	0.000
Q84.8 Other specified congenital malformations of integument	0.002	0.998	0.000
Q84.6 Other congenital malformations of nails	0.002	0.998	0.000
Q84.5 Enlarged and hypertrophic nails	0.002	0.998	0.000
Q84.4 Congenital leukonychia	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations