TreeWAS – Variant ID: rs9958208

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.892	0.108
I80 Phlebitis and thrombophlebitis	0.000	0.894	0.106
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.901	0.099
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.905	0.095
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.917	0.083
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.919	0.081
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.923	0.077
I86 Varicose veins of other sites	0.000	0.924	0.076
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.927	0.073
I82 Other venous embolism and thrombosis	0.000	0.928	0.072
I87 Other disorders of veins	0.000	0.930	0.070
I86.8 Varicose veins of other specified sites	0.000	0.932	0.067
I82.8 Embolism and thrombosis of other specified veins	0.000	0.933	0.067
I86.1 Scrotal varices	0.000	0.937	0.063
I83 Varicose veins of lower extremities	0.000	0.938	0.062
I84.3 External thrombosed haemorrhoids	0.000	0.940	0.060
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.940	0.059
I87.1 Compression of vein	0.000	0.941	0.059
I86.4 Gastric varices	0.000	0.941	0.059
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.941	0.059
I84.1 Internal haemorrhoids with other complications	0.000	0.942	0.058
I87.8 Other specified disorders of veins	0.000	0.942	0.057
I84 Haemorrhoids	0.000	0.943	0.057
I88 Nonspecific lymphadenitis	0.000	0.944	0.056
I86.3 Vulval varices	0.000	0.945	0.055
I86.2 Pelvic varices	0.000	0.945	0.055
I86.0 Sublingual varices	0.000	0.945	0.055
I82.1 Thrombophlebitis migrans	0.000	0.948	0.052
I82.0 Budd-Chiari syndrome	0.000	0.948	0.052
I87.9 Disorder of vein, unspecified	0.000	0.949	0.051
I87.0 Postphlebitic syndrome	0.000	0.949	0.051
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.951	0.049
I82.2 Embolism and thrombosis of vena cava	0.000	0.953	0.047
I84.0 Internal thrombosed haemorrhoids	0.000	0.953	0.047
I85 Oesophageal varices	0.000	0.954	0.045
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.956	0.044
I84.4 External haemorrhoids with other complications	0.000	0.956	0.044
I81 Portal vein thrombosis	0.000	0.956	0.044
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.958	0.042
I88.8 Other nonspecific lymphadenitis	0.000	0.959	0.041
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.959	0.041
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.959	0.041
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.959	0.041
I82.3 Embolism and thrombosis of renal vein	0.000	0.960	0.039
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.961	0.038
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.965	0.035
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.969	0.031
I85.0 Oesophageal varices with bleeding	0.000	0.972	0.028
I85.9 Oesophageal varices without bleeding	0.000	0.973	0.027
I89.1 Lymphangitis	0.000	0.974	0.026
I84.7 Unspecified thrombosed haemorrhoids	0.000	0.978	0.021
I89.0 Lymphoedema, not elsewhere classified	0.000	0.979	0.021
I84.8 Unspecified haemorrhoids with other complications	0.000	0.979	0.021
H65.3 Chronic mucoid otitis media	0.021	0.979	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.983	0.017
H65 Nonsuppurative otitis media	0.016	0.984	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.015	0.985	0.000
T91 Sequelae of injuries of neck and trunk	0.014	0.986	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.014	0.986	0.000
T91.3 Sequelae of injury of spinal cord	0.013	0.987	0.000
I84.6 Residual haemorrhoidal skin tags	0.000	0.987	0.013
T90 Sequelae of injuries of head	0.013	0.987	0.000
T92 Sequelae of injuries of upper limb	0.013	0.987	0.000
T90.5 Sequelae of intracranial injury	0.013	0.987	0.000
J31.0 Chronic rhinitis	0.013	0.987	0.000
T92.0 Sequelae of open wound of upper limb	0.013	0.987	0.000
H65.4 Other chronic nonsuppurative otitis media	0.012	0.987	0.000
T91.1 Sequelae of fracture of spine	0.012	0.988	0.000
T90.9 Sequelae of unspecified injury of head	0.012	0.988	0.000
K50.8 Other Crohn's disease	0.012	0.988	0.000
H65.1 Other acute nonsuppurative otitis media	0.011	0.988	0.000
H65.0 Acute serous otitis media	0.011	0.988	0.000
K50.9 Crohn's disease, unspecified	0.011	0.989	0.000
T95 Sequelae of burns, corrosions and frostbite	0.011	0.989	0.000
T98 Sequelae of other and unspecified effects of external causes	0.011	0.989	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.011	0.989	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.011	0.989	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.011	0.989	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.011	0.989	0.000
K50 Crohn's disease [regional enteritis]	0.011	0.989	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.010	0.990	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.010	0.990	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.010	0.990	0.000
M25.57 Pain in joint (Ankle and foot)	0.000	0.990	0.010
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.010	0.990	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.010	0.990	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.010	0.990	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.010	0.990	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.010	0.990	0.000
H65.2 Chronic serous otitis media	0.010	0.990	0.000
T90.3 Sequelae of injury of cranial nerves	0.010	0.990	0.000
T90.1 Sequelae of open wound of head	0.010	0.990	0.000
T90.0 Sequelae of superficial injury of head	0.010	0.990	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.009	0.990	0.000
T90.4 Sequelae of injury of eye and orbit	0.009	0.991	0.000
K50.0 Crohn's disease of small intestine	0.009	0.991	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.009	0.991	0.000
Z04.8 Examination and observation for other specified reasons	0.000	0.991	0.009
T93 Sequelae of injuries of lower limb	0.009	0.991	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.009	0.991	0.000
T90.8 Sequelae of other specified injuries of head	0.009	0.991	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.009	0.991	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.009	0.991	0.000
T94.1 Sequelae of injuries, not specified by body region	0.009	0.991	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.008	0.992	0.000
T92.1 Sequelae of fracture of arm	0.008	0.992	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.008	0.992	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.008	0.992	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.008	0.992	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.008	0.992	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.008	0.992	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.008	0.992	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.008	0.992	0.000
T98.2 Sequelae of certain early complications of trauma	0.008	0.992	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.008	0.992	0.000
I47.1 Supraventricular tachycardia	0.000	0.992	0.008
T92.2 Sequelae of fracture at wrist and hand level	0.008	0.992	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.008	0.992	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.008	0.992	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.008	0.992	0.000
T93.2 Sequelae of other fractures of lower limb	0.008	0.992	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.007	0.993	0.000
I84.5 External haemorrhoids without complication	0.000	0.993	0.007
G31.8 Other specified degenerative diseases of nervous system	0.007	0.993	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.007	0.993	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.007	0.993	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.007	0.993	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.007	0.993	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.006	0.994	0.000
K50.1 Crohn's disease of large intestine	0.006	0.994	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.006	0.994	0.000
G30.9 Alzheimer's disease, unspecified	0.006	0.994	0.000
T93.0 Sequelae of open wound of lower limb	0.006	0.994	0.000
T93.1 Sequelae of fracture of femur	0.005	0.995	0.000
G30 Alzheimer's disease	0.005	0.995	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.005	0.995	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.005	0.995	0.000
G30-G32 Other degenerative diseases of the nervous system	0.005	0.995	0.000
C81 Hodgkin's disease	0.005	0.995	0.000
C81.9 Hodgkin's disease, unspecified	0.005	0.995	0.000
I84.2 Internal haemorrhoids without complication	0.000	0.995	0.005
N92.6 Irregular menstruation, unspecified	0.005	0.995	0.000
G31.0 Circumscribed brain atrophy	0.004	0.996	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.004	0.996	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.996	0.004
C83 Diffuse non-Hodgkin's lymphoma	0.004	0.996	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.004	0.996	0.000
C81.1 Nodular sclerosis	0.004	0.996	0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.004	0.996	0.000
C83.0 Small cell (diffuse)	0.004	0.996	0.000
C95 Leukaemia of unspecified cell type	0.004	0.996	0.000
G82.2 Paraplegia, unspecified	0.004	0.996	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.004	0.996	0.000
E21.0 Primary hyperparathyroidism	0.004	0.996	0.000
E21.3 Hyperparathyroidism, unspecified	0.004	0.996	0.000
C95.9 Leukaemia, unspecified	0.004	0.996	0.000
C91 Lymphoid leukaemia	0.004	0.996	0.000
G30.8 Other Alzheimer's disease	0.004	0.996	0.000
G30.1 Alzheimer's disease with late onset	0.004	0.996	0.000
C88 Malignant immunoproliferative diseases	0.004	0.996	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.996	0.004
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.004	0.996	0.000
G30.0 Alzheimer's disease with early onset	0.004	0.996	0.000
Z72.1 Alcohol use	0.000	0.996	0.004
C91.9 Lymphoid leukaemia, unspecified	0.004	0.996	0.000
G31.2 Degeneration of nervous system due to alcohol	0.004	0.996	0.000
J31.1 Chronic nasopharyngitis	0.004	0.996	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.004	0.996	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.996	0.004
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.004	0.996	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.004	0.996	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.004	0.996	0.000
C81.7 Other Hodgkin's disease	0.004	0.996	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.004	0.996	0.000
C81.3 Lymphocytic depletion	0.004	0.996	0.000
C81.2 Mixed cellularity	0.004	0.996	0.000
C81.0 Lymphocytic predominance	0.004	0.996	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.996	0.004
O72.1 Other immediate postpartum haemorrhage	0.000	0.996	0.004
J31.2 Chronic pharyngitis	0.003	0.996	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.996	0.004
C90 Multiple myeloma and malignant plasma cell neoplasms	0.004	0.996	0.000
C91.0 Acute lymphoblastic leukaemia	0.003	0.996	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.003	0.996	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.003	0.996	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.003	0.997	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
C94 Other leukaemias of specified cell type	0.003	0.997	0.000
C93 Monocytic leukaemia	0.003	0.997	0.000
C86 Other specified types of T/NK-cell lymphoma	0.003	0.997	0.000
C91.5 Adult T-cell leukaemia	0.003	0.997	0.000
C83.7 Burkitt's tumour	0.003	0.997	0.000
C83.6 Undifferentiated (diffuse)	0.003	0.997	0.000
C83.5 Lymphoblastic (diffuse)	0.003	0.997	0.000
C83.4 Immunoblastic (diffuse)	0.003	0.997	0.000
C83.2 Mixed small and large cell (diffuse)	0.003	0.997	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.003	0.997	0.000
C83.3 Large cell (diffuse)	0.003	0.997	0.000
C91.4 Hairy-cell leukaemia	0.003	0.997	0.000
C95.7 Other leukaemia of unspecified cell type	0.003	0.997	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.003	0.997	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.003	0.997	0.000
C95.0 Acute leukaemia of unspecified cell type	0.003	0.997	0.000
E21.2 Other hyperparathyroidism	0.003	0.997	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.003	0.997	0.000
C91.7 Other lymphoid leukaemia	0.003	0.997	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.003	0.997	0.000
C91.3 Prolymphocytic leukaemia	0.003	0.997	0.000
C91.2 Subacute lymphocytic leukaemia	0.003	0.997	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.003	0.997	0.000
C82.3 Follicular lymphoma grade IIIa	0.003	0.997	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.003	0.997	0.000
C88.7 Other malignant immunoproliferative diseases	0.003	0.997	0.000
C88.3 Immunoproliferative small intestinal disease	0.003	0.997	0.000
C88.2 Gamma heavy chain disease	0.003	0.997	0.000
C88.1 Alpha heavy chain disease	0.003	0.997	0.000
Z04 Examination and observation for other reasons	0.000	0.997	0.003
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.003	0.997	0.000
C82.2 Large cell, follicular	0.003	0.997	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.003	0.997	0.000
C90.2 Plasmacytoma, extramedullary	0.003	0.997	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.997	0.003
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.003	0.997	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.003	0.997	0.000
C83.1 Small cleaved cell (diffuse)	0.003	0.997	0.000
C82.6 Cutaneous follicle centre lymphoma	0.003	0.997	0.000
C82.5 Diffuse follicle centre lymphoma	0.003	0.997	0.000
C82.4 Follicular lymphoma grade IIIb	0.003	0.997	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.003	0.997	0.000
C82.0 Small cleaved cell, follicular	0.003	0.997	0.000
C84.0 Mycosis fungoides	0.003	0.997	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.003	0.997	0.000
E21.4 Other specified disorders of parathyroid gland	0.003	0.997	0.000
K35 Acute appendicitis	0.000	0.997	0.003
C90.3 Solitary plasmacytoma	0.003	0.997	0.000
C90.1 Plasma cell leukaemia	0.003	0.997	0.000
C92 Myeloid leukaemia	0.003	0.997	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.003	0.997	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.003	0.997	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.003	0.997	0.000
C86.4 Blastic NK-cell lymphoma	0.003	0.997	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.003	0.997	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.003	0.997	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.003	0.997	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.003	0.997	0.000
C93.9 Monocytic leukaemia, unspecified	0.003	0.997	0.000
C93.7 Other monocytic leukaemia	0.003	0.997	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.003	0.997	0.000
C93.2 Subacute monocytic leukaemia	0.003	0.997	0.000
C93.1 Chronic monocytic leukaemia	0.003	0.997	0.000
C93.0 Acute monocytic leukaemia	0.003	0.997	0.000
C94.7 Other specified leukaemias	0.003	0.997	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.003	0.997	0.000
C94.5 Acute myelofibrosis	0.003	0.997	0.000
C94.4 Acute panmyelosis	0.003	0.997	0.000
C94.3 Mast cell leukaemia	0.003	0.997	0.000
C94.2 Acute megakaryoblastic leukaemia	0.003	0.997	0.000
C94.1 Chronic erythraemia	0.003	0.997	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.003	0.997	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.003	0.997	0.000
C96.8 Histiocytic sarcoma	0.003	0.997	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.003	0.997	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.003	0.997	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.003	0.997	0.000
C96.3 True histiocytic lymphoma	0.003	0.997	0.000
C96.2 Malignant mast cell tumour	0.003	0.997	0.000
C96.1 Malignant histiocytosis	0.003	0.997	0.000
C96.0 Letterer-Siwe disease	0.003	0.997	0.000
C50.1 Central portion of breast	0.003	0.997	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.002	0.997	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.002	0.997	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.002	0.997	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.002	0.997	0.000
C84.4 Peripheral T-cell lymphoma	0.002	0.997	0.000
C84.3 Lymphoepithelioid lymphoma	0.002	0.997	0.000
C84.2 T-zone lymphoma	0.002	0.997	0.000
C84.1 Sezary's diease	0.002	0.997	0.000
C90.0 Multiple myeloma	0.003	0.997	0.000
G62.8 Other specified polyneuropathies	0.000	0.997	0.003
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.002	0.997	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.003	0.997	0.000
C92.4 Acute promyelocytic leukaemia	0.002	0.997	0.000
K35.3 Acute appendicitis with localized peritonitis	0.000	0.997	0.003
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.002	0.997	0.000
G82.5 Tetraplegia, unspecified	0.002	0.997	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.002	0.997	0.000
G82 Paraplegia and tetraplegia	0.003	0.997	0.000
Z04.6 General psychiatric examination, requested by authority	0.000	0.997	0.002
Z04.4 Examination and observation following alleged rape and seduction	0.000	0.997	0.002
Z04.2 Examination and observation following work accident	0.000	0.997	0.002
Z04.0 Blood-alcohol and blood-drug test	0.000	0.997	0.002
Z04.1 Examination and observation following transport accident	0.000	0.997	0.002
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.998	0.002
C50.2 Upper-inner quadrant of breast	0.002	0.998	0.000
Z04.5 Examination and observation following other inflicted injury	0.000	0.998	0.002
Z72 Problems related to lifestyle	0.000	0.998	0.002
C84.5 Other and unspecified T-cell lymphomas	0.002	0.998	0.000
S02.2 Fracture of nasal bones	0.000	0.998	0.002
K35.2 Acute appendicitis with generalized peritonitis	0.000	0.998	0.002
R07.0 Pain in throat	0.002	0.998	0.000
Z04.9 Examination and observation for unspecified reason	0.000	0.998	0.002
M19.02 Primary arthrosis of other joints (Upper arm)	0.002	0.998	0.000
C92.9 Myeloid leukaemia, unspecified	0.002	0.998	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.002	0.998	0.000
C92.7 Other myeloid leukaemia	0.002	0.998	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.002	0.998	0.000
C92.5 Acute myelomonocytic leukaemia	0.002	0.998	0.000
C92.3 Myeloid sarcoma	0.002	0.998	0.000
C92.2 Subacute myeloid leukaemia	0.002	0.998	0.000
C91.1 Chronic lymphocytic leukaemia	0.002	0.998	0.000
Z04.3 Examination and observation following other accident	0.000	0.998	0.002
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.002	0.998	0.000
N73.6 Female pelvic peritoneal adhesions	0.002	0.998	0.000
G62.9 Polyneuropathy, unspecified	0.000	0.998	0.002
H47.1 Papilloedema, unspecified	0.002	0.998	0.000
I78.1 Naevus, nonneoplastic	0.000	0.998	0.002
G62 Other polyneuropathies	0.000	0.998	0.002
R00.1 Bradycardia, unspecified	0.000	0.998	0.002
G82.4 Spastic tetraplegia	0.002	0.998	0.000
G82.3 Flaccid tetraplegia	0.002	0.998	0.000
G82.0 Flaccid paraplegia	0.002	0.998	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.998	0.002
M19.0 Primary arthrosis of other joints	0.002	0.998	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.002	0.998	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.998	0.002
C43.5 Malignant melanoma of trunk	0.000	0.998	0.002
S42.40 Fracture of lower end of humerus (closed)	0.002	0.998	0.000
B02.9 Zoster without complication	0.002	0.998	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.002	0.998	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.002	0.998	0.000
G63.2 Diabetic polyneuropathy	0.000	0.998	0.002
Z72.9 Problem related to lifestyle, unspecified	0.000	0.998	0.002
Z72.8 Other problems related to lifestyle	0.000	0.998	0.002
Z72.6 Gambling and betting	0.000	0.998	0.002
Z72.5 High-risk sexual behaviour	0.000	0.998	0.002
Z72.4 Inappropriate diet and eating habits	0.000	0.998	0.002
Z72.3 Lack of physical exercise	0.000	0.998	0.002
Z72.2 Drug use	0.000	0.998	0.002
I47 Paroxysmal tachycardia	0.000	0.998	0.002
S02.21 Fracture of nasal bones (open)	0.000	0.998	0.002
R45.1 Restlessness and agitation	0.002	0.998	0.000
Z72.0 Tobacco use	0.000	0.998	0.002
M79.67 Pain in limb (Ankle and foot)	0.000	0.998	0.002
K61.0 Anal abscess	0.000	0.998	0.002
Y83.6 Removal of other organ (partial) (total)	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.998	0.002
M54.16 Radiculopathy (Lumbar region)	0.000	0.998	0.002
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.002	0.998	0.000
C85.0 Lymphosarcoma	0.002	0.998	0.000
C92.0 Acute myeloid leukaemia	0.002	0.998	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.998	0.002
R59.1 Generalised enlarged lymph nodes	0.002	0.998	0.000
W07.0 Home	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
S72.30 Fracture of shaft of femur (closed)	0.002	0.998	0.000
G06.1 Intraspinal abscess and granuloma	0.002	0.998	0.000
I74 Arterial embolism and thrombosis	0.000	0.998	0.002
C85.7 Other specified types of non-Hodgkin's lymphoma	0.002	0.998	0.000
H47.2 Optic atrophy	0.002	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.000	0.998	0.002
G62.2 Polyneuropathy due to other toxic agents	0.000	0.998	0.002
G62.1 Alcoholic polyneuropathy	0.000	0.998	0.002
M79.63 Pain in limb (Forearm)	0.000	0.998	0.002
M19.08 Primary arthrosis of other joints (Other)	0.002	0.998	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.002	0.998	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.002	0.998	0.000
K35.8 Acute appendicitis, other and unspecified	0.000	0.998	0.002
E04.1 Non-toxic single thyroid nodule	0.000	0.998	0.002
H47 Other disorders of optic [2nd] nerve and visual pathways	0.002	0.998	0.000
O36.5 Maternal care for poor foetal growth	0.000	0.998	0.002
H04.5 Stenosis and insufficiency of lachrymal passages	0.000	0.998	0.002
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.998	0.002
M79.64 Pain in limb (Hand)	0.000	0.998	0.002
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.000	0.998	0.002
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.998	0.002
H54.9 Unspecified visual impairment (binocular)	0.000	0.998	0.002
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.998	0.002
C85.1 B-cell lymphoma, unspecified	0.002	0.998	0.000
H46 Optic neuritis	0.002	0.998	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.001	0.998	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.998	0.002
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
G12.2 Motor neuron disease	0.000	0.998	0.002
G62.0 Drug-induced polyneuropathy	0.000	0.998	0.001
I78 Diseases of capillaries	0.000	0.998	0.002
C92.1 Chronic myeloid leukaemia	0.001	0.998	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.998	0.001
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.998	0.001
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.998	0.001
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.998	0.001
S32.40 Fracture of acetabulum (closed)	0.000	0.998	0.001
G06.2 Extradural and subdural abscess, unspecified	0.001	0.998	0.000
R63.0 Anorexia	0.000	0.998	0.002
A41.8 Other specified septicaemia	0.002	0.998	0.000
I74.8 Embolism and thrombosis of other arteries	0.000	0.998	0.001
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.001
Z42.1 Follow-up care involving plastic surgery of breast	0.000	0.998	0.002
H47.7 Disorder of visual pathways, unspecified	0.001	0.998	0.000
H47.6 Disorders of visual cortex	0.001	0.998	0.000
H47.5 Disorders of other visual pathways	0.001	0.998	0.000
H47.4 Disorders of optic chiasm	0.001	0.998	0.000
K29.3 Chronic superficial gastritis	0.000	0.998	0.002
T86.1 Kidney transplant failure and rejection	0.000	0.998	0.001
S02.50 Fracture of tooth (closed)	0.000	0.998	0.001
G06.0 Intracranial abscess and granuloma	0.001	0.998	0.000
K66.0 Peritoneal adhesions	0.000	0.998	0.002
S27.1 Traumatic haemothorax	0.001	0.998	0.000
Y60.0 During surgical operation	0.000	0.998	0.001
E23.0 Hypopituitarism	0.001	0.998	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.998	0.001
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.998	0.001
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.998	0.001
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.998	0.001
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.998	0.001
G63.1 Polyneuropathy in neoplastic disease	0.000	0.998	0.001
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
S31.1 Open wound of abdominal wall	0.001	0.998	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.998	0.001
G06 Intracranial and intraspinal abscess and granuloma	0.001	0.998	0.000
N13.3 Other and unspecified hydronephrosis	0.000	0.999	0.001
E06.3 Autoimmune thyroiditis	0.001	0.999	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.000	0.999	0.001
T82.3 Mechanical complication of other vascular grafts	0.000	0.999	0.001
I47.0 Reentry ventricular arrhythmia	0.000	0.999	0.001
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.999	0.001
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.999	0.001
Z02.8 Other examinations for administrative purposes	0.000	0.999	0.001
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.999	0.001
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.999	0.001
B02.3 Zoster ocular disease	0.001	0.999	0.000
I78.9 Disease of capillaries, unspecified	0.000	0.999	0.001
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.999	0.001
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.999	0.001
H35.6 Retinal haemorrhage	0.001	0.999	0.000
M75.2 Bicipital tendinitis	0.000	0.999	0.001
X41.9 Unspecified place	0.001	0.999	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.999	0.001
K35-K38 Diseases of appendix	0.000	0.999	0.001
M25.71 Osteophyte (Shoulder region)	0.001	0.999	0.000
M89.88 Other specified disorders of bone (Other)	0.001	0.999	0.000
F40.2 Specific (isolated) phobias	0.001	0.999	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.001	0.999	0.000
S42.4 Fracture of lower end of humerus	0.001	0.999	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.000	0.999	0.001
H47.3 Other disorders of optic disk	0.001	0.999	0.000
S27.2 Traumatic heamopneumothorax	0.001	0.999	0.000
J80 Adult respiratory distress syndrome	0.001	0.999	0.000
K37 Unspecified appendicitis	0.000	0.999	0.001
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.999	0.001
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.001	0.999	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
I78.8 Other diseases of capillaries	0.000	0.999	0.001
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.999	0.001
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.001	0.999	0.000
M75.3 Calcific tendinitis of shoulder	0.001	0.999	0.000
T87.6 Other and unspecified complications of amputation stump	0.000	0.999	0.001
T86 Failure and rejection of transplanted organs and tissues	0.000	0.999	0.001
I77.0 Arteriovenous fistula, acquired	0.000	0.999	0.001
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.999	0.001
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.999	0.001
M87.98 Osteonecrosis, unspecified (Other)	0.001	0.999	0.000
K55.0 Acute vascular disorders of intestine	0.000	0.999	0.001
G64 Other disorders of peripheral nervous system	0.000	0.999	0.001
K36 Other appendicitis	0.000	0.999	0.001
S32.50 Fracture of pubis (closed)	0.000	0.999	0.001
K31.5 Obstruction of duodenum	0.000	0.999	0.001
S32.7 Multiple fractures of lumbar spine and pelvis	0.001	0.999	0.000
S32.4 Fracture of acetabulum	0.000	0.999	0.001
T78.4 Allergy, unspecified	0.001	0.999	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.000	0.999	0.001
I77 Other disorders of arteries and arterioles	0.000	0.999	0.001
H11.0 Pterygium	0.000	0.999	0.001
I72.3 Aneurysm of iliac artery	0.000	0.999	0.001
S72.3 Fracture of shaft of femur	0.001	0.999	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
S42.41 Fracture of lower end of humerus (open)	0.001	0.999	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.001	0.999	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.001	0.999	0.000
S02.5 Fracture of tooth	0.000	0.999	0.001
T42.4 Benzodiazepines	0.001	0.999	0.000
G61 Inflammatory polyneuropathy	0.000	0.999	0.001
G60 Hereditary and idiopathic neuropathy	0.000	0.999	0.001
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.999	0.001
H46-H48 Disorders of optic nerve and visual pathways	0.001	0.999	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.999	0.001
M19.01 Primary arthrosis of other joints (Shoulder region)	0.001	0.999	0.000
S52.01 Fracture of upper end of ulna (open)	0.001	0.999	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.000	0.999	0.001
I70.0 Atherosclerosis of aorta	0.000	0.999	0.001
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.999	0.001
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.000	0.999	0.001
T86.4 Liver transplant failure and rejection	0.000	0.999	0.001
T86.3 Heart-lung transplant failure and rejection	0.000	0.999	0.001
T86.2 Heart transplant failure and rejection	0.000	0.999	0.001
T86.0 Bone-marrow transplant rejection	0.000	0.999	0.001
I70 Atherosclerosis	0.000	0.999	0.001
A04.8 Other specified bacterial intestinal infections	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations