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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs997277
log Bayes Factor = 0.251184
Chromosome 2   position 189,750,863  (GRCh37) Explore rs997277 on Ensembl!
Variant rs997277 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M48.06 Spinal stenosis (Lumbar region)
0.000 0.501 0.499
M48.0 Spinal stenosis
0.000 0.503 0.497
M48.09 Spinal stenosis (Site unspecified)
0.000 0.512 0.488
M48.00 Spinal stenosis (Multiple sites in spine)
0.000 0.558 0.442
M48.04 Spinal stenosis (Thoracic region)
0.000 0.567 0.433
M48.02 Spinal stenosis (Cervical region)
0.000 0.583 0.417
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.000 0.606 0.394
M48.05 Spinal stenosis (Thoracolumbar region)
0.000 0.644 0.356
M48.03 Spinal stenosis (Cervicothoracic region)
0.000 0.644 0.356
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.000 0.644 0.356
M48 Other spondylopathies
0.000 0.741 0.259
M48.5 Collapsed vertebra, not elsewhere classified
0.000 0.800 0.200
M48.8 Other specified spondylopathies
0.000 0.812 0.188
M48.9 Spondylopathy, unspecified
0.000 0.812 0.188
M48.4 Fatigue fracture of vertebra
0.000 0.814 0.186
M48.3 Traumatic spondylopathy
0.000 0.814 0.186
M48.2 Kissing spine
0.000 0.814 0.186
M48.1 Ankylosing hyperostosis [Forestier]
0.000 0.814 0.186
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.000 0.816 0.184
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.000 0.833 0.167
M48.99 Spondylopathy, unspecified (Site unspecified)
0.000 0.855 0.145
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.000 0.856 0.144
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)
0.000 0.856 0.144
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)
0.000 0.856 0.144
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)
0.000 0.856 0.144
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)
0.000 0.856 0.144
M48.86 Other specified spondylopathies (Lumbar region)
0.000 0.860 0.139
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)
0.000 0.861 0.139
M48.92 Spondylopathy, unspecified (Cervical region)
0.000 0.862 0.138
M48.89 Other specified spondylopathies (Site unspecified)
0.000 0.865 0.135
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)
0.000 0.865 0.135
M48.85 Other specified spondylopathies (Thoracolumbar region)
0.000 0.865 0.135
M48.84 Other specified spondylopathies (Thoracic region)
0.000 0.865 0.135
M48.83 Other specified spondylopathies (Cervicothoracic region)
0.000 0.865 0.135
M48.82 Other specified spondylopathies (Cervical region)
0.000 0.865 0.135
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)
0.000 0.865 0.135
M48.80 Other specified spondylopathies (Multiple sites in spine)
0.000 0.865 0.135
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.000 0.865 0.135
M48.97 Spondylopathy, unspecified (Lumbosacral region)
0.000 0.865 0.135
M48.95 Spondylopathy, unspecified (Thoracolumbar region)
0.000 0.865 0.135
M48.94 Spondylopathy, unspecified (Thoracic region)
0.000 0.865 0.135
M48.93 Spondylopathy, unspecified (Cervicothoracic region)
0.000 0.865 0.135
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)
0.000 0.865 0.135
M48.90 Spondylopathy, unspecified (Multiple sites in spine)
0.000 0.865 0.135
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)
0.000 0.867 0.133
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)
0.000 0.867 0.133
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)
0.000 0.867 0.133
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)
0.000 0.867 0.133
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)
0.000 0.867 0.133
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)
0.000 0.867 0.133
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)
0.000 0.867 0.133
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)
0.000 0.867 0.133
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)
0.000 0.867 0.133
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)
0.000 0.867 0.133
M48.29 Kissing spine (Site unspecified)
0.000 0.867 0.133
M48.28 Kissing spine (Sacral and sacrococcygeal region)
0.000 0.867 0.133
M48.27 Kissing spine (Lumbosacral region)
0.000 0.867 0.133
M48.26 Kissing spine (Lumbar region)
0.000 0.867 0.133
M48.25 Kissing spine (Thoracolumbar region)
0.000 0.867 0.133
M48.24 Kissing spine (Thoracic region)
0.000 0.867 0.133
M48.23 Kissing spine (Cervicothoracic region)
0.000 0.867 0.133
M48.22 Kissing spine (Cervical region)
0.000 0.867 0.133
M48.21 Kissing spine (Occipito-atlanto-axial region)
0.000 0.867 0.133
M48.20 Kissing spine (Multiple sites in spine)
0.000 0.867 0.133
M48.39 Traumatic spondylopathy (Site unspecified)
0.000 0.867 0.133
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)
0.000 0.867 0.133
M48.37 Traumatic spondylopathy (Lumbosacral region)
0.000 0.867 0.133
M48.36 Traumatic spondylopathy (Lumbar region)
0.000 0.867 0.133
M48.35 Traumatic spondylopathy (Thoracolumbar region)
0.000 0.867 0.133
M48.34 Traumatic spondylopathy (Thoracic region)
0.000 0.867 0.133
M48.33 Traumatic spondylopathy (Cervicothoracic region)
0.000 0.867 0.133
M48.32 Traumatic spondylopathy (Cervical region)
0.000 0.867 0.133
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)
0.000 0.867 0.133
M48.30 Traumatic spondylopathy (Multiple sites in spine)
0.000 0.867 0.133
M48.49 Fatigue fracture of vertebra (Site unspecified)
0.000 0.867 0.133
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)
0.000 0.867 0.133
M48.47 Fatigue fracture of vertebra (Lumbosacral region)
0.000 0.867 0.133
M48.46 Fatigue fracture of vertebra (Lumbar region)
0.000 0.867 0.133
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)
0.000 0.867 0.133
M48.44 Fatigue fracture of vertebra (Thoracic region)
0.000 0.867 0.133
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)
0.000 0.867 0.133
M48.42 Fatigue fracture of vertebra (Cervical region)
0.000 0.867 0.133
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)
0.000 0.867 0.133
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)
0.000 0.867 0.133
M48.87 Other specified spondylopathies (Lumbosacral region)
0.000 0.868 0.132
M48.96 Spondylopathy, unspecified (Lumbar region)
0.000 0.879 0.121
M48.07 Spinal stenosis (Lumbosacral region)
0.001 0.904 0.096
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.001 0.909 0.090
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.000 0.913 0.087
C50.1 Central portion of breast
0.000 0.915 0.085
Y52 Agents primarily affecting the cardiovascular system
0.000 0.962 0.038
Y52.4 Angiotensin-converting-enzyme inhibitors
0.000 0.965 0.035
M47.86 Other spondylosis (Lumbar region)
0.000 0.965 0.035
Y52.3 Coronary vasodilators, not elsewhere classified
0.000 0.965 0.034
Y52.1 Calcium-channel blockers
0.000 0.966 0.034
M45-M49 Spondylopathies
0.000 0.967 0.033
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.968 0.032
M47.8 Other spondylosis
0.000 0.968 0.032
Y42.5 Other oestrogens and progestogens
0.000 0.969 0.031
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.969 0.031
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.000 0.969 0.031
Y45.0 Opioids and related analgesics
0.000 0.970 0.030
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.000 0.970 0.029
M47.89 Other spondylosis (Site unspecified)
0.000 0.971 0.029
Y51 Drugs primarily affecting the autonomic nervous system
0.000 0.971 0.029
Y44 Agents primarily affecting blood constituents
0.000 0.971 0.029
M47.85 Other spondylosis (Thoracolumbar region)
0.000 0.972 0.028
M47 Spondylosis
0.000 0.972 0.028
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.000 0.972 0.028
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.972 0.028
Y45.2 Propionic acid derivatives
0.000 0.972 0.028
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.973 0.027
Y52.8 Antivaricose drugs, including sclerosing agents
0.000 0.973 0.027
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.973 0.027
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.000 0.973 0.027
M47.80 Other spondylosis (Multiple sites in spine)
0.000 0.973 0.027
Y52.7 Peripheral vasodilators
0.000 0.974 0.026
Y42.7 Androgens and anabolic congeners
0.000 0.975 0.025
Y42.0 Glucocorticoids and synthetic analogs
0.000 0.975 0.025
M47.83 Other spondylosis (Cervicothoracic region)
0.000 0.975 0.025
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.975 0.025
Y49 Psychotropic drugs, not elsewhere classified
0.000 0.975 0.025
Y42.1 Thyroid hormones and substitutes
0.000 0.975 0.025
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.000 0.976 0.024
M47.84 Other spondylosis (Thoracic region)
0.000 0.976 0.024
Y47 Sedatives, hypnotics and antianxiety drugs
0.000 0.976 0.024
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.000 0.977 0.023
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.000 0.977 0.023
Y44.2 Anticoagulants
0.000 0.977 0.023
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.977 0.023
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.000 0.977 0.023
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.000 0.977 0.023
Y42.9 Other and unspecified hormone antagonists
0.000 0.977 0.023
Y44.5 Thrombolytic drugs
0.000 0.977 0.023
Y42.4 Oral contraceptives
0.000 0.978 0.022
Y50 Central nervous system stimulants, not elsewhere classified
0.000 0.978 0.022
Y59 Other and unspecified vaccines and biological substances
0.000 0.978 0.022
Y49.5 Other antipsychotics and neuroleptics
0.000 0.978 0.022
Y58 Bacterial vaccines
0.000 0.978 0.022
Y45.4 Antirheumatics
0.000 0.979 0.021
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.000 0.979 0.021
Y45.5 4-Aminophenol derivatives
0.000 0.979 0.021
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.979 0.021
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.979 0.021
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.979 0.021
Y51.1 Other parasympathomimetics [cholinergics]
0.000 0.979 0.021
Y51.0 Anticholinesterase agents
0.000 0.979 0.021
Y44.9 Other and unspecified agents affecting blood constituents
0.000 0.979 0.021
Y44.7 Plasma substitutes
0.000 0.979 0.021
Y44.6 Natural blood and blood products
0.000 0.979 0.021
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.000 0.979 0.021
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.000 0.979 0.021
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.979 0.021
M49 Spondylopathies in diseases classified elsewhere
0.000 0.979 0.020
M47.0 Anterior spinal and vertebral artery compression syndromes
0.000 0.980 0.020
Y42.2 Antithyroid drugs
0.000 0.980 0.020
Y46 Antiepileptics and anti-Parkinsonism drugs
0.000 0.980 0.020
Y53 Agents primarily affecting the gastro-intestinal system
0.000 0.980 0.020
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.980 0.020
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.000 0.980 0.020
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.000 0.981 0.019
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.000 0.981 0.019
Y47.1 Benzodiazepines
0.000 0.981 0.018
Y49.0 Tricyclic and tetracyclic antidepressants
0.000 0.982 0.018
Y49.9 Psychotropic drug, unspecified
0.000 0.982 0.018
Y49.8 Other psychotropic drugs, not elsewhere classified
0.000 0.982 0.018
Y49.7 Psychostimulants with abuse potential
0.000 0.982 0.018
Y49.6 Psychodysleptics [hallucinogens]
0.000 0.982 0.018
Y49.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.982 0.018
Y49.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.982 0.018
Y49.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.982 0.018
Y43 Primarily systemic agents
0.000 0.982 0.018
Y45.1 Salicylates
0.000 0.983 0.017
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified
0.000 0.983 0.017
Y47.8 Other sedatives, hypnotics and antianxiety drugs
0.000 0.983 0.017
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified
0.000 0.983 0.017
Y47.4 Bromine compounds
0.000 0.983 0.017
Y47.3 Paraldehyde
0.000 0.983 0.017
Y47.2 Chloral derivatives
0.000 0.983 0.017
Y47.0 Barbiturates, not elsewhere classified
0.000 0.983 0.017
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.983 0.017
M47.1 Other spondylosis with myelopathy
0.000 0.983 0.017
Y59.3 Immunoglobulin
0.000 0.983 0.016
Y48 Anaesthetics and therapeutic gases
0.000 0.983 0.016
Y41 Other systemic anti-infectives and antiparasitics
0.000 0.984 0.016
Y50.9 Central nervous system stimulant, unspecified
0.000 0.984 0.016
Y50.8 Other central nervous system stimulants
0.000 0.984 0.016
Y50.2 Methylxanthines, not elsewhere classified
0.000 0.984 0.016
Y50.1 Opioid receptor antagonists
0.000 0.984 0.016
Y50.0 Analeptics
0.000 0.984 0.016
Y59.9 Vaccine or biological substance, unspecified
0.000 0.984 0.016
Y59.8 Other specified vaccines and biological substances
0.000 0.984 0.016
Y59.2 Protozoal vaccines
0.000 0.984 0.016
Y59.1 Rickettsial vaccines
0.000 0.984 0.016
Y54.3 Benzothiadiazine derivatives
0.000 0.984 0.016
Y58.9 Other and unspecified bacterial vaccines
0.000 0.984 0.016
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component
0.000 0.984 0.016
Y58.6 Pertussis vaccine, including combinations with a pertussis component
0.000 0.984 0.016
Y58.5 Diphtheria vaccine
0.000 0.984 0.016
Y58.4 Tetanus vaccine
0.000 0.984 0.016
Y58.3 Plague vaccine
0.000 0.984 0.016
Y58.2 Cholera vaccine
0.000 0.984 0.016
Y58.1 Typhoid and paratyphoid vaccine
0.000 0.984 0.016
Y43.4 Immunosuppressive agents
0.000 0.984 0.016
Y46.2 Hydantoin derivatives
0.000 0.984 0.016
Y46.7 Anti-Parkinsonism drugs
0.000 0.984 0.016
Y58.0 BCG vaccine
0.000 0.984 0.015
Y59.0 Viral vaccines
0.000 0.985 0.015
Y53.4 Other laxatives
0.000 0.985 0.015
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.985 0.015
M49.4 Neuropathic spondylopathy
0.000 0.985 0.015
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.985 0.015
M49.2 Enterobacterial spondylitis
0.000 0.985 0.015
M49.1 Brucella spondylitis
0.000 0.985 0.015
M49.0 Tuberculosis of spine
0.000 0.985 0.015
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)
0.000 0.985 0.015
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)
0.000 0.985 0.015
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)
0.000 0.985 0.015
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)
0.000 0.985 0.015
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)
0.000 0.985 0.015
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)
0.000 0.985 0.015
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)
0.000 0.985 0.015
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)
0.000 0.985 0.015
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)
0.000 0.985 0.015
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)
0.000 0.985 0.015
Y46.8 Antispasticity drugs
0.000 0.985 0.015
Y46.5 Valproic acid
0.000 0.985 0.015
Y46.3 Deoxybarbiturates
0.000 0.985 0.015
Y46.1 Oxazolidinediones
0.000 0.985 0.015
Y46.0 Succinimides
0.000 0.985 0.015
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.985 0.015
Y53.7 Emetics
0.000 0.985 0.015
Y53.6 Antidiarrhoeal drugs
0.000 0.985 0.015
Y53.5 Digestants
0.000 0.985 0.015
Y53.3 Saline and osmotic laxatives
0.000 0.985 0.015
Y53.2 Stimulant laxatives
0.000 0.985 0.015
Y53.0 Histamine H2-receptor antagonists
0.000 0.985 0.015
Y49.2 Other and unspecified antidepressants
0.000 0.985 0.015
Y53.1 Other antacids and anti-gastric-secretion drugs
0.000 0.985 0.014
Y57 Other and unspecified drugs and medicaments
0.000 0.985 0.015
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.985 0.015
Y54.4 Loop [high-ceiling] diuretics
0.000 0.985 0.014
Y54.7 Agents affecting calcification
0.000 0.986 0.014
Y56.9 Topical agent, unspecified
0.000 0.986 0.014
Y56.8 Other topical agents
0.000 0.986 0.014
Y56.7 Dental drugs, topically applied
0.000 0.986 0.014
Y56.6 Otorhinolaryngological drugs and preparations
0.000 0.986 0.014
Y56.5 Ophthalmological drugs and preparations
0.000 0.986 0.014
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.986 0.014
Y56.2 Local astringents and local detergents
0.000 0.986 0.014
Y56.1 Antipruritics
0.000 0.986 0.014
Y56.3 Emollients, demulcents and protectants
0.000 0.986 0.014
Y46.4 Iminostilbenes
0.000 0.986 0.014
Y54.9 Mineral salts, not elsewhere classified
0.000 0.986 0.014
Y54.6 Electrolytic, caloric and water-balance agents
0.000 0.986 0.014
Y54.2 Carbonic-anhydrase inhibitors
0.000 0.986 0.014
Y54.0 Mineralocorticoids
0.000 0.986 0.014
Y45.8 Other analgesics and antipyretics
0.000 0.986 0.013
Y41.5 Antiviral drugs
0.000 0.986 0.013
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.000 0.987 0.013
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.000 0.987 0.013
Y43.9 Primarily systemic agent, unspecified
0.000 0.987 0.013
Y43.8 Other primarily systemic agents, not elsewhere classified
0.000 0.987 0.013
Y43.6 Enzymes, not elsewhere classified
0.000 0.987 0.013
Y43.5 Acidifying and alkalising agents
0.000 0.987 0.013
Y43.1 Antineoplastic antimetabolites
0.000 0.987 0.013
Y55.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.988 0.012
Y55.5 Anticommon cold drugs
0.000 0.988 0.012
Y55.3 Antitussives
0.000 0.988 0.012
Y55.2 Other and unspecified agents primarily acting on muscles
0.000 0.988 0.012
Y55.0 Oxytocic drugs
0.000 0.988 0.012
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.988 0.012
Y48.4 Anaesthetic, unspecified
0.000 0.988 0.012
Y53.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.988 0.012
M47.19 Other spondylosis with myelopathy (Site unspecified)
0.000 0.988 0.012
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)
0.000 0.988 0.012
M47.17 Other spondylosis with myelopathy (Lumbosacral region)
0.000 0.988 0.012
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)
0.000 0.988 0.012
M47.14 Other spondylosis with myelopathy (Thoracic region)
0.000 0.988 0.012
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)
0.000 0.988 0.012
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)
0.000 0.988 0.012
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)
0.000 0.988 0.012
Y43.0 Antiallergic and antiemetic drugs
0.000 0.988 0.012
Y48.5 Therapeutic gases
0.000 0.988 0.012
Y48.1 Parenteral anaesthetics
0.000 0.988 0.012
Y48.0 Inhaled anaesthetics
0.000 0.988 0.012
Y41.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.988 0.012
Y41.4 Anthelminthics
0.000 0.988 0.012
Y41.3 Other antiprotozoal drugs
0.000 0.988 0.012
Y41.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.988 0.012
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.988 0.012
Y54.8 Agents affecting uric acid metabolism
0.000 0.988 0.012
M47.16 Other spondylosis with myelopathy (Lumbar region)
0.000 0.988 0.012
Y41.1 Antimycobacterial drugs
0.000 0.988 0.011
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.988 0.011
Y46.6 Other and unspecified antiepileptics
0.000 0.989 0.011
M49.09 Tuberculosis of spine (Site unspecified)
0.000 0.989 0.011
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M49.07 Tuberculosis of spine (Lumbosacral region)
0.000 0.989 0.011
M49.06 Tuberculosis of spine (Lumbar region)
0.000 0.989 0.011
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.000 0.989 0.011
M49.04 Tuberculosis of spine (Thoracic region)
0.000 0.989 0.011
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.000 0.989 0.011
M49.02 Tuberculosis of spine (Cervical region)
0.000 0.989 0.011
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)
0.000 0.989 0.011
M49.00 Tuberculosis of spine (Multiple sites in spine)
0.000 0.989 0.011
M49.19 Brucella spondylitis (Site unspecified)
0.000 0.989 0.011
M49.18 Brucella spondylitis (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M49.17 Brucella spondylitis (Lumbosacral region)
0.000 0.989 0.011
M49.16 Brucella spondylitis (Lumbar region)
0.000 0.989 0.011
M49.15 Brucella spondylitis (Thoracolumbar region)
0.000 0.989 0.011
M49.14 Brucella spondylitis (Thoracic region)
0.000 0.989 0.011
M49.13 Brucella spondylitis (Cervicothoracic region)
0.000 0.989 0.011
M49.12 Brucella spondylitis (Cervical region)
0.000 0.989 0.011
M49.11 Brucella spondylitis (Occipito-atlanto-axial region)
0.000 0.989 0.011
M49.10 Brucella spondylitis (Multiple sites in spine)
0.000 0.989 0.011
M49.29 Enterobacterial spondylitis (Site unspecified)
0.000 0.989 0.011
M49.28 Enterobacterial spondylitis (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M49.27 Enterobacterial spondylitis (Lumbosacral region)
0.000 0.989 0.011
M49.26 Enterobacterial spondylitis (Lumbar region)
0.000 0.989 0.011
M49.25 Enterobacterial spondylitis (Thoracolumbar region)
0.000 0.989 0.011
M49.24 Enterobacterial spondylitis (Thoracic region)
0.000 0.989 0.011
M49.23 Enterobacterial spondylitis (Cervicothoracic region)
0.000 0.989 0.011
M49.22 Enterobacterial spondylitis (Cervical region)
0.000 0.989 0.011
M49.21 Enterobacterial spondylitis (Occipito-atlanto-axial region)
0.000 0.989 0.011
M49.20 Enterobacterial spondylitis (Multiple sites in spine)
0.000 0.989 0.011
M49.39 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Site unspecified)
0.000 0.989 0.011
M49.38 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M49.37 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbosacral region)
0.000 0.989 0.011
M49.36 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbar region)
0.000 0.989 0.011
M49.35 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracolumbar region)
0.000 0.989 0.011
M49.34 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracic region)
0.000 0.989 0.011
M49.33 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervicothoracic region)
0.000 0.989 0.011
M49.32 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervical region)
0.000 0.989 0.011
M49.31 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Occipito-atlanto-axial region)
0.000 0.989 0.011
M49.30 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Multiple sites in spine)
0.000 0.989 0.011
M49.49 Neuropathic spondylopathy (Site unspecified)
0.000 0.989 0.011
M49.48 Neuropathic spondylopathy (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M49.47 Neuropathic spondylopathy (Lumbosacral region)
0.000 0.989 0.011
M49.46 Neuropathic spondylopathy (Lumbar region)
0.000 0.989 0.011
M49.45 Neuropathic spondylopathy (Thoracolumbar region)
0.000 0.989 0.011
M49.44 Neuropathic spondylopathy (Thoracic region)
0.000 0.989 0.011
M49.43 Neuropathic spondylopathy (Cervicothoracic region)
0.000 0.989 0.011
M49.42 Neuropathic spondylopathy (Cervical region)
0.000 0.989 0.011
M49.41 Neuropathic spondylopathy (Occipito-atlanto-axial region)
0.000 0.989 0.011
M49.40 Neuropathic spondylopathy (Multiple sites in spine)
0.000 0.989 0.011
M49.89 Spondylopathy in other diseases classified elsewhere (Site unspecified)
0.000 0.989 0.011
M49.88 Spondylopathy in other diseases classified elsewhere (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M49.87 Spondylopathy in other diseases classified elsewhere (Lumbosacral region)
0.000 0.989 0.011
M49.86 Spondylopathy in other diseases classified elsewhere (Lumbar region)
0.000 0.989 0.011
M49.85 Spondylopathy in other diseases classified elsewhere (Thoracolumbar region)
0.000 0.989 0.011
M49.84 Spondylopathy in other diseases classified elsewhere (Thoracic region)
0.000 0.989 0.011
M49.83 Spondylopathy in other diseases classified elsewhere (Cervicothoracic region)
0.000 0.989 0.011
M49.82 Spondylopathy in other diseases classified elsewhere (Cervical region)
0.000 0.989 0.011
M49.81 Spondylopathy in other diseases classified elsewhere (Occipito-atlanto-axial region)
0.000 0.989 0.011
M49.80 Spondylopathy in other diseases classified elsewhere (Multiple sites in spine)
0.000 0.989 0.011
Y57.6 Other diagnostic agents
0.000 0.989 0.011
Y43.2 Antineoplastic natural products
0.000 0.989 0.011
Y57.7 Vitamins, not elsewhere classified
0.000 0.989 0.011
Y57.4 Pharmaceutical excipients
0.000 0.989 0.011
Y57.3 Alcohol deterrents
0.000 0.989 0.011
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.000 0.989 0.011
Y57.1 Lipotropic drugs
0.000 0.989 0.011
Y57.0 Appetite depressants [anorectics]
0.000 0.989 0.011
Y55.4 Expectorants
0.000 0.989 0.010
Y41.0 Sulphonamides
0.000 0.989 0.010
M45 Ankylosing spondylitis
0.000 0.990 0.010
Y55.6 Antiasthmatics, not elsewhere classified
0.000 0.990 0.010
Y57.8 Other drugs and medicaments
0.000 0.990 0.010
M47.2 Other spondylosis with radiculopathy
0.000 0.990 0.010
N76 Other inflammation of vagina and vulva
0.010 0.990 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.000 0.990 0.010
Y48.3 Local anaesthetics
0.000 0.990 0.009
N76.1 Subacute and chronic vaginitis
0.009 0.990 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.000 0.991 0.009
Y48.2 Other and unspecified general anaesthetics
0.000 0.991 0.009
N76.0 Acute vaginitis
0.009 0.991 0.000
Y57.5 X-ray contrast media
0.000 0.991 0.009
N76.6 Ulceration of vulva
0.009 0.991 0.000
N76.2 Acute vulvitis
0.009 0.991 0.000
Y54.5 Other diuretics
0.000 0.991 0.008
Q23.1 Congenital insufficiency of aortic valve
0.009 0.991 0.000
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)
0.000 0.991 0.008
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)
0.000 0.991 0.008
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)
0.000 0.991 0.008
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)
0.000 0.991 0.008
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)
0.000 0.991 0.008
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)
0.000 0.991 0.008
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)
0.000 0.991 0.008
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)
0.000 0.992 0.008
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.000 0.992 0.008
M46 Other inflammatory spondylopathies
0.001 0.992 0.008
N76.4 Abscess of vulva
0.008 0.992 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.000 0.992 0.008
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)
0.000 0.992 0.007
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.992 0.007
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.992 0.007
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.992 0.007
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.992 0.007
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.992 0.007
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.992 0.007
N76.5 Ulceration of vagina
0.008 0.992 0.000
N76.3 Subacute and chronic vulvitis
0.008 0.992 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.993 0.007
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.000 0.993 0.007
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.000 0.993 0.007
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.000 0.993 0.007
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.000 0.993 0.007
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.000 0.993 0.007
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.000 0.993 0.007
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.000 0.993 0.007
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)
0.000 0.993 0.007
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.000 0.993 0.006
Y57.9 Drug or medicament, unspecified
0.000 0.993 0.006
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.994 0.006
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.994 0.006
M46.2 Osteomyelitis of vertebra
0.001 0.994 0.006
M46.8 Other specified inflammatory spondylopathies
0.001 0.994 0.006
M46.5 Other infective spondylopathies
0.001 0.994 0.006
M46.0 Spinal enthesopathy
0.000 0.994 0.006
M46.3 Infection of intervertebral disk (pyogenic)
0.001 0.994 0.005
M54.39 Sciatica (Site unspecified)
0.000 0.994 0.006
K12.1 Other forms of stomatitis
0.000 0.994 0.006
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.000 0.994 0.006
N76.8 Other specified inflammation of vagina and vulva
0.005 0.994 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.001 0.995 0.005
Y40 Systemic antibiotics
0.000 0.995 0.005
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.001 0.995 0.004
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.005 0.995 0.000
Y40.3 Macrolides
0.000 0.995 0.005
Q23 Congenital malformations of aortic and mitral valves
0.005 0.995 0.000
J86.9 Pyothorax without fistula
0.000 0.995 0.005
M46.24 Osteomyelitis of vertebra (Thoracic region)
0.000 0.995 0.004
M46.29 Osteomyelitis of vertebra (Site unspecified)
0.001 0.995 0.004
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)
0.001 0.995 0.004
M46.27 Osteomyelitis of vertebra (Lumbosacral region)
0.001 0.995 0.004
M46.26 Osteomyelitis of vertebra (Lumbar region)
0.001 0.995 0.004
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)
0.001 0.995 0.004
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)
0.001 0.995 0.004
M46.22 Osteomyelitis of vertebra (Cervical region)
0.001 0.995 0.004
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)
0.001 0.995 0.004
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)
0.001 0.995 0.004
M46.09 Spinal enthesopathy (Site unspecified)
0.000 0.995 0.004
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)
0.000 0.995 0.004
M46.07 Spinal enthesopathy (Lumbosacral region)
0.000 0.995 0.004
M46.05 Spinal enthesopathy (Thoracolumbar region)
0.000 0.995 0.004
M46.04 Spinal enthesopathy (Thoracic region)
0.000 0.995 0.004
M46.03 Spinal enthesopathy (Cervicothoracic region)
0.000 0.995 0.004
M46.02 Spinal enthesopathy (Cervical region)
0.000 0.995 0.004
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)
0.000 0.995 0.004
M46.00 Spinal enthesopathy (Multiple sites in spine)
0.000 0.995 0.004
M46.59 Other infective spondylopathies (Site unspecified)
0.001 0.995 0.004
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)
0.001 0.995 0.004
M46.57 Other infective spondylopathies (Lumbosacral region)
0.001 0.995 0.004
M46.56 Other infective spondylopathies (Lumbar region)
0.001 0.995 0.004
M46.55 Other infective spondylopathies (Thoracolumbar region)
0.001 0.995 0.004
M46.54 Other infective spondylopathies (Thoracic region)
0.001 0.995 0.004
M46.53 Other infective spondylopathies (Cervicothoracic region)
0.001 0.995 0.004
M46.52 Other infective spondylopathies (Cervical region)
0.001 0.995 0.004
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)
0.001 0.995 0.004
M46.50 Other infective spondylopathies (Multiple sites in spine)
0.001 0.995 0.004
M46.89 Other specified inflammatory spondylopathies (Site unspecified)
0.001 0.995 0.004
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)
0.001 0.995 0.004
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)
0.001 0.995 0.004
M46.86 Other specified inflammatory spondylopathies (Lumbar region)
0.001 0.995 0.004
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)
0.001 0.995 0.004
M46.84 Other specified inflammatory spondylopathies (Thoracic region)
0.001 0.995 0.004
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)
0.001 0.995 0.004
M46.82 Other specified inflammatory spondylopathies (Cervical region)
0.001 0.995 0.004
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)
0.001 0.995 0.004
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)
0.001 0.995 0.004
M46.06 Spinal enthesopathy (Lumbar region)
0.000 0.995 0.004
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)
0.001 0.995 0.004
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)
0.001 0.995 0.004
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)
0.001 0.995 0.004
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)
0.001 0.995 0.004
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)
0.001 0.995 0.004
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)
0.001 0.995 0.004
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)
0.001 0.995 0.004
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)
0.001 0.995 0.004
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)
0.000 0.996 0.004
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)
0.000 0.996 0.004
K12.3 Oral mucositis (ulcerative)
0.000 0.996 0.004
Y40.6 Rifamycins
0.000 0.996 0.004
K12 Stomatitis and related lesions
0.000 0.996 0.004
Z74.1 Need for assistance with personal care
0.000 0.996 0.004
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral
0.001 0.996 0.004
M46.16 Sacroiliitis, not elsewhere classified-Lumbar
0.001 0.996 0.004
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar
0.001 0.996 0.004
M46.14 Sacroiliitis, not elsewhere classified-Thoracic
0.001 0.996 0.004
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic
0.001 0.996 0.004
M46.12 Sacroiliitis, not elsewhere classified-Cervical
0.001 0.996 0.004
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl
0.001 0.996 0.004
M46.10 Sacroiliitis, not elsewhere classified-Mult site
0.001 0.996 0.004
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.996 0.004
E24.9 Cushing's syndrome, unspecified
0.000 0.996 0.004
Y40.2 Chloramphenicol group
0.000 0.996 0.004
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.000 0.996 0.004
Z74.2 Need for assistance at home and no other household member able to render care
0.000 0.996 0.004
M46.4 Discitis, unspecified
0.001 0.996 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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