TreeWAS – Variant ID: rs9976946

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D50.8 Other iron deficiency anaemias	0.011	0.989	0.000
J98.1 Pulmonary collapse	0.010	0.990	0.000
D50 Iron deficiency anaemia	0.009	0.991	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.008	0.992	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.008	0.992	0.000
R15 Faecal incontinence	0.000	0.992	0.008
F41.2 Mixed anxiety and depressive disorder	0.007	0.993	0.000
D50.9 Iron deficiency anaemia, unspecified	0.007	0.993	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.993	0.007
N92.3 Ovulation bleeding	0.000	0.993	0.007
D50.1 Sideropenic dysphagia	0.007	0.993	0.000
O36.8 Maternal care for other specified foetal problems	0.000	0.993	0.007
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.994	0.006
O36 Maternal care for other known or suspected foetal problems	0.000	0.994	0.006
T39.0 Salicylates	0.000	0.994	0.006
O48 Prolonged pregnancy	0.000	0.995	0.005
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.995	0.005
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.995	0.005
O36.6 Maternal care for excessive foetal growth	0.000	0.995	0.005
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.995	0.005
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.995	0.005
Z80.3 Family history of malignant neoplasm of breast	0.005	0.995	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.005	0.995	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.005	0.995	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.995	0.005
T43.2 Other and unspecified antidepressants	0.000	0.995	0.005
J95.8 Other postprocedural respiratory disorders	0.005	0.995	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.995	0.005
O36.2 Maternal care for hydrops foetalis	0.000	0.995	0.005
D50-D53 Nutritional anaemias	0.005	0.995	0.000
O36.5 Maternal care for poor foetal growth	0.000	0.995	0.005
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.995	0.005
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.995	0.005
J95.0 Tracheostomy malfunction	0.005	0.995	0.000
J98 Other respiratory disorders	0.005	0.995	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.995	0.004
T39.2 Pyrazolone derivatives	0.000	0.995	0.004
O36.1 Maternal care for other isoimmunisation	0.000	0.996	0.004
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.996	0.004
O36.4 Maternal care for intra-uterine death	0.000	0.996	0.004
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.996	0.004
O33 Maternal care for known or suspected disproportion	0.000	0.996	0.004
T43.9 Psychotropic drug, unspecified	0.000	0.996	0.004
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.996	0.004
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.996	0.004
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.996	0.004
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.996	0.004
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.996	0.004
O45 Premature separation of placenta [abruptio placentae]	0.000	0.996	0.004
O40 Polyhydramnios	0.000	0.996	0.004
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.996	0.004
O43 Placental disorders	0.000	0.996	0.004
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.996	0.004
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.996	0.004
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.996	0.004
J95-J99 Other diseases of the respiratory system	0.004	0.996	0.000
J95.9 Postprocedural respiratory disorder, unspecified	0.004	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.996	0.004
T43.6 Psychostimulants with abuse potential	0.000	0.996	0.004
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.996	0.004
O36.9 Maternal care for foetal problem, unspecified	0.000	0.996	0.004
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.996	0.004
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.996	0.004
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.996	0.004
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.996	0.004
I65.2 Occlusion and stenosis of carotid artery	0.004	0.996	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.996	0.004
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.996	0.004
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.996	0.004
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.996	0.004
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.996	0.004
T42.4 Benzodiazepines	0.000	0.996	0.004
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.996	0.004
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.996	0.004
J95.5 Postprocedural subglottic stenosis	0.004	0.996	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.996	0.004
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.996	0.004
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.004	0.996	0.000
N83.2 Other and unspecified ovarian cysts	0.004	0.996	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.996	0.004
Z95.2 Presence of prosthetic heart valve	0.004	0.996	0.000
O31 Complications specific to multiple gestation	0.000	0.996	0.004
T36 Poisoning by systemic antibiotics	0.000	0.996	0.004
D53 Other nutritional anaemias	0.004	0.996	0.000
J95.4 Mendelson's syndrome	0.004	0.996	0.000
J95.3 Chronic pulmonary insufficiency following surgery	0.004	0.996	0.000
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.004	0.996	0.000
O33.9 Maternal care for disproportion, unspecified	0.000	0.996	0.004
O42 Premature rupture of membranes	0.000	0.996	0.004
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.996	0.004
N28 Other disorders of kidney and ureter, not elsewhere classified	0.004	0.996	0.000
T39.1 4-Aminophenol derivatives	0.000	0.996	0.004
T42.0 Hydantoin derivatives	0.000	0.996	0.004
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.996	0.004
O44 Placenta praevia	0.000	0.996	0.003
J98.6 Disorders of diaphragm	0.003	0.996	0.000
O45.9 Premature separation of placenta, unspecified	0.000	0.996	0.003
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.996	0.003
T42.2 Succinimides and oxazolidinediones	0.000	0.996	0.003
O32.0 Maternal care for unstable lie	0.000	0.996	0.003
D52 Folate deficiency anaemia	0.003	0.996	0.000
J98.3 Compensatory emphysema	0.003	0.996	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.996	0.004
N28.1 Cyst of kidney, acquired	0.004	0.996	0.000
O32.2 Maternal care for transverse and oblique lie	0.000	0.996	0.003
O32.4 Maternal care for high head at term	0.000	0.996	0.003
T42.3 Barbiturates	0.000	0.996	0.003
T42.1 Iminostilbenes	0.000	0.996	0.003
O33.5 Maternal care for disproportion due to unusually large foetus	0.000	0.996	0.003
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.996	0.003
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.997	0.003
T46.1 Calcium-channel blockers	0.000	0.997	0.003
O30 Multiple gestation	0.000	0.997	0.003
O34.8 Maternal care for other abnormalities of pelvic organs	0.000	0.997	0.003
J99 Respiratory disorders in diseases classified elsewhere	0.003	0.997	0.000
O43.1 Malformation of placenta	0.000	0.997	0.003
O43.9 Placental disorder, unspecified	0.000	0.997	0.003
T45.0 Antiallergic and antiemetic drugs	0.000	0.997	0.003
O47 False labour	0.001	0.997	0.003
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.997	0.003
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.997	0.003
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.997	0.003
J98.9 Respiratory disorder, unspecified	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.997	0.003
J98.2 Interstitial emphysema	0.003	0.997	0.000
O33.8 Maternal care for disproportion of other origin	0.000	0.997	0.003
O33.7 Maternal care for disproportion due to other foetal deformities	0.000	0.997	0.003
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.000	0.997	0.003
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.000	0.997	0.003
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.000	0.997	0.003
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.000	0.997	0.003
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.000	0.997	0.003
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.000	0.997	0.003
J98.5 Diseases of mediastinum, not elsewhere classified	0.003	0.997	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.997	0.003
O41 Other disorders of amniotic fluid and membranes	0.000	0.997	0.003
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.997	0.003
O32.8 Maternal care for other malpresentation of foetus	0.000	0.997	0.003
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.997	0.003
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.000	0.997	0.003
T38.0 Glucocorticoids and synthetic analogues	0.000	0.997	0.003
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.997	0.003
O45.8 Other premature separation of placenta	0.000	0.997	0.003
O45.0 Premature separation of placenta with coagulation defect	0.000	0.997	0.003
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.997	0.003
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.997	0.003
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.997	0.003
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.997	0.003
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.997	0.003
T44.0 Anticholinesterase agents	0.000	0.997	0.003
O42.9 Premature rupture of membranes, unspecified	0.000	0.997	0.003
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.997	0.003
T38.1 Thyroid hormones and substitutes	0.000	0.997	0.003
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.997	0.003
T38.9 Other and unspecified hormone antagonists	0.000	0.997	0.003
T38.7 Androgens and anabolic congeners	0.000	0.997	0.003
T38.4 Oral contraceptives	0.000	0.997	0.003
T38.2 Antithyroid drugs	0.000	0.997	0.003
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.997	0.003
J98.8 Other specified respiratory disorders	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.997	0.003
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.997	0.003
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.997	0.003
D51 Vitamin B12 deficiency anaemia	0.003	0.997	0.000
O43.2 Morbidly adherent placenta	0.000	0.997	0.003
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.997	0.003
T46.7 Peripheral vasodilators	0.000	0.997	0.003
N28.8 Other specified disorders of kidney and ureter	0.003	0.997	0.000
O43.0 Placental transfusion syndromes	0.000	0.997	0.003
J99.8 Respiratory disorders in other diseases classified elsewhere	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.000	0.997	0.003
T41.2 Other and unspecified general anaesthetics	0.000	0.997	0.003
J96 Respiratory failure, not elsewhere classified	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.997	0.003
T37.5 Antiviral drugs	0.000	0.997	0.003
T37.4 Anthelminthics	0.000	0.997	0.003
T37.3 Other antiprotozoal drugs	0.000	0.997	0.003
T37.1 Antimycobacterial drugs	0.000	0.997	0.003
T37.0 Sulphonamides	0.000	0.997	0.003
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.997	0.003
T41.5 Therapeutic gases	0.000	0.997	0.003
T41.4 Anaesthetic, unspecified	0.000	0.997	0.003
T41.3 Local anaesthetics	0.000	0.997	0.003
T41.1 Intravenous anaesthetics	0.000	0.997	0.003
T41.0 Inhaled anaesthetics	0.000	0.997	0.003
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.997	0.003
T45.8 Other primarily systemic and haematological agents	0.000	0.997	0.003
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.997	0.003
T45.6 Fibrinolysis-affecting drugs	0.000	0.997	0.003
T45.3 Enzymes, not elsewhere classified	0.000	0.997	0.003
O32.6 Maternal care for compound presentation	0.000	0.997	0.003
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.997	0.003
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.997	0.003
D53.9 Nutritional anaemia, unspecified	0.003	0.997	0.000
T45.4 Iron and its compounds	0.000	0.997	0.003
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.003	0.997	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.997	0.003
O43.8 Other placental disorders	0.000	0.997	0.003
T48.5 Anti-common-cold drugs	0.000	0.997	0.003
T36.8 Other systemic antibiotics	0.000	0.997	0.003
T45.5 Anticoagulants	0.000	0.997	0.003
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.997	0.003
T48.4 Expectorants	0.000	0.997	0.003
T48.3 Antitussives	0.000	0.997	0.003
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.997	0.003
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.997	0.003
T48.0 Oxytocic drugs	0.000	0.997	0.003
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.997	0.003
T47.2 Stimulant laxatives	0.000	0.997	0.003
T49.9 Topical agent, unspecified	0.000	0.997	0.003
T49.8 Other topical agents	0.000	0.997	0.003
T49.7 Dental drugs, topically applied	0.000	0.997	0.003
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.997	0.003
T49.5 Ophthalmological drugs and preparations	0.000	0.997	0.003
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.997	0.003
T49.3 Emollients, demulcents and protectants	0.000	0.997	0.003
T49.2 Local astringents and local detergents	0.000	0.997	0.003
T49.1 Antipruritics	0.000	0.997	0.003
T50.7 Analeptics and opioid receptor antagonists	0.000	0.997	0.003
T50.5 Appetite depressants	0.000	0.997	0.003
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.997	0.003
T50.0 Mineralocorticoids and their antagonists	0.000	0.997	0.003
O31.8 Other complications specific to multiple gestation	0.000	0.997	0.003
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.000	0.997	0.003
O31.0 Papyraceous foetus	0.000	0.997	0.003
T36.3 Macrolides	0.000	0.997	0.003
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.997	0.003
D53.8 Other specified nutritional anaemias	0.003	0.997	0.000
D53.2 Scorbutic anaemia	0.003	0.997	0.000
D53.0 Protein deficiency anaemia	0.003	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.997	0.003
T36.7 Antifungal antibiotics, systemically used	0.000	0.997	0.003
T36.6 Rifamycins	0.000	0.997	0.003
T36.5 Aminoglycosides	0.000	0.997	0.003
T36.2 Chloramphenicol group	0.000	0.997	0.003
T50.8 Diagnostic agents	0.000	0.997	0.003
T50.4 Drugs affecting uric acid metabolism	0.000	0.997	0.003
O34.6 Maternal care for abnormality of vagina	0.000	0.997	0.003
T50.1 Loop [high-ceiling] diuretics	0.000	0.997	0.003
O31.1 Continuing pregnancy after abortion of one foetus or more	0.000	0.997	0.003
O44.1 Placenta praevia with haemorrhage	0.000	0.997	0.003
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.997	0.003
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.997	0.003
O32.3 Maternal care for face, brow and chin presentation	0.000	0.997	0.003
T36.0 Penicillins	0.000	0.997	0.003
T45.2 Vitamins, not elsewhere classified	0.000	0.997	0.003
T36.4 Tetracyclines	0.000	0.997	0.003
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.997	0.003
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.997	0.003
T47.7 Emetics	0.000	0.997	0.003
T47.5 Digestants	0.000	0.997	0.003
T47.3 Saline and osmotic laxatives	0.000	0.997	0.003
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.997	0.003
O47.9 False labour, unspecified	0.000	0.997	0.002
O34.3 Maternal care for cervical incompetence	0.000	0.997	0.003
N28.0 Ischaemia and infarction of kidney	0.003	0.997	0.000
O34.4 Maternal care for other abnormalities of cervix	0.000	0.997	0.003
D52.8 Other folate deficiency anaemias	0.003	0.997	0.000
D52.1 Drug-induced folate deficiency anaemia	0.003	0.997	0.000
D52.0 Dietary folate deficiency anaemia	0.003	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.000	0.997	0.003
O30.1 Triplet pregnancy	0.000	0.997	0.003
T47.4 Other laxatives	0.000	0.997	0.003
T47.0 Histamine H(2)-receptor antagonists	0.000	0.997	0.003
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
T40.2 Other opioids	0.000	0.997	0.003
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.997	0.003
D52.9 Folate deficiency anaemia, unspecified	0.003	0.997	0.000
O34.0 Maternal care for congenital malformation of uterus	0.000	0.997	0.003
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.997	0.003
O47.1 False labour at or after 37 completed weeks of gestation	0.002	0.997	0.001
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.997	0.003
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.000	0.997	0.003
O34.5 Maternal care for other abnormalities of gravid uterus	0.000	0.997	0.003
O30.9 Multiple gestation, unspecified	0.000	0.997	0.003
O30.8 Other multiple gestation	0.000	0.997	0.003
O30.2 Quadruplet pregnancy	0.000	0.997	0.003
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.997	0.003
T40.8 Lysergide [LSD]	0.000	0.997	0.003
T40.7 Cannabis (derivatives)	0.000	0.997	0.003
T40.0 Opium	0.000	0.997	0.003
Z93.2 Ileostomy status	0.003	0.997	0.000
T40.3 Methadone	0.000	0.997	0.002
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.003	0.997	0.000
J99.0 Rheumatoid lung disease	0.002	0.997	0.000
O41.1 Infection of amniotic sac and membranes	0.000	0.997	0.002
T40.1 Heroin	0.000	0.997	0.002
D51.8 Other vitamin B12 deficiency anaemias	0.002	0.997	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.002	0.997	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.002	0.997	0.000
T40.5 Cocaine	0.000	0.997	0.002
Z95.3 Presence of xenogenic heart valve	0.003	0.997	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.997	0.002
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.003	0.997	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.003	0.997	0.000
D51.2 Transcobalamin II deficiency	0.002	0.997	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.002	0.997	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.997	0.002
D51.3 Other dietary vitamin B12 deficiency anaemia	0.002	0.997	0.000
J96.9 Respiratory failure, unspecified	0.002	0.997	0.000
J96.1 Chronic respiratory failure	0.002	0.997	0.000
J96.0 Acute respiratory failure	0.002	0.997	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.997	0.002
T40.4 Other synthetic narcotics	0.000	0.997	0.002
O34.7 Maternal care for abnormality of vulva and perineum	0.000	0.997	0.002
Z95.4 Presence of other heart-valve replacement	0.003	0.997	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.997	0.002
T40.6 Other and unspecified narcotics	0.000	0.997	0.002
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.998	0.002
Z95.1 Presence of aortocoronary bypass graft	0.002	0.998	0.000
O46.8 Other antepartum haemorrhage	0.000	0.998	0.002
O47.0 False labour before 37 completed weeks of gestation	0.001	0.998	0.002
H54.0 Blindness, both eyes	0.000	0.998	0.002
J98.4 Other disorders of lung	0.002	0.998	0.000
O41.0 Oligohydramnios	0.000	0.998	0.002
R33 Retention of urine	0.002	0.998	0.000
O34.1 Maternal care for tumour of corpus uteri	0.000	0.998	0.002
Z95.8 Presence of other cardiac and vascular implants and grafts	0.002	0.998	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.998	0.002
I65.0 Occlusion and stenosis of vertebral artery	0.002	0.998	0.000
O30.0 Twin pregnancy	0.000	0.998	0.002
Y43.3 Other antineoplastic drugs	0.002	0.998	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.002	0.998	0.000
M19.9 Arthrosis, unspecified	0.002	0.998	0.000
M19.94 Arthrosis, unspecified (Hand)	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.002	0.998	0.000
I65.1 Occlusion and stenosis of basilar artery	0.002	0.998	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.002	0.998	0.000
J96.09 Acute respiratory failure; Type unspecified	0.002	0.998	0.000
J96.01 Acute respiratory failure; Type II [hypercapnic]	0.002	0.998	0.000
J96.00 Acute respiratory failure; Type I [hypoxic]	0.002	0.998	0.000
J96.19 Chronic respiratory failure; Type unspecified	0.002	0.998	0.000
J96.11 Chronic respiratory failure; Type II [hypercapnic]	0.002	0.998	0.000
J96.10 Chronic respiratory failure; Type I [hypoxic]	0.002	0.998	0.000
J96.99 Respiratory failure, unspecified; Type unspecified	0.002	0.998	0.000
J96.91 Respiratory failure unspecified; Type II [hypercapnic]	0.002	0.998	0.000
J96.90 Respiratory failure, unspecified; Type I [hypoxic]	0.002	0.998	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.002	0.998	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.002	0.998	0.000
Z91.6 Personal history of other physical trauma	0.000	0.998	0.002
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.002	0.998	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.002	0.998	0.000
Z80 Family history of malignant neoplasm	0.002	0.998	0.000
O32.1 Maternal care for breech presentation	0.001	0.998	0.001
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.002	0.998	0.000
I35.0 Aortic (valve) stenosis	0.002	0.998	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.002	0.998	0.000
D75.1 Secondary polycythaemia	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.998	0.002
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.002	0.998	0.000
H54 Blindness and low vision	0.000	0.998	0.002
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.002	0.998	0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.002	0.998	0.000
F41.1 Generalised anxiety disorder	0.002	0.998	0.000
C61 Malignant neoplasm of prostate	0.000	0.998	0.002
F41 Other anxiety disorders	0.002	0.998	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
D76.3 Other histiocytosis syndromes	0.002	0.998	0.000
H54.6 Unqualified visual loss, one eye	0.000	0.998	0.002
H54.4 Blindness, one eye	0.000	0.998	0.002
D75 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
I35.1 Aortic (valve) insufficiency	0.002	0.998	0.000
D73 Diseases of spleen	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
L30.9 Dermatitis, unspecified	0.002	0.998	0.000
N87.1 Moderate cervical dysplasia	0.000	0.998	0.002
M19.92 Arthrosis, unspecified (Upper arm)	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
Z80.6 Family history of leukaemia	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.998	0.000
D89.3 Immune reconstitution syndrome	0.001	0.998	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.002	0.998	0.000
D55-D59 Haemolytic anaemias	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.998	0.000
F05.9 Delirium, unspecified	0.002	0.998	0.000
O46.9 Antepartum haemorrhage, unspecified	0.000	0.998	0.001
I64 Stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
F41.3 Other mixed anxiety disorders	0.002	0.998	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.002	0.998	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.000	0.998	0.002
D73.0 Hyposplenism	0.002	0.998	0.000
H54.2 Low vision, both eyes	0.000	0.998	0.002
H54.5 Low vision, one eye	0.000	0.998	0.002
D74 Methaemoglobinaemia	0.002	0.998	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.002	0.998	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.001	0.998	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.002	0.998	0.000
D75.2 Essential thrombocytosis	0.002	0.998	0.000
M41.9 Scoliosis, unspecified	0.000	0.998	0.002
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.002	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.998	0.002
D73.8 Other diseases of spleen	0.001	0.998	0.000
D75.0 Familial erythrocytosis	0.001	0.998	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.001	0.998	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.001	0.998	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.001	0.998	0.000
E07.9 Disorder of thyroid, unspecified	0.002	0.998	0.000
H54.3 Unqualified visual loss, both eyes	0.000	0.998	0.001
M67.8 Other specified disorders of synovium and tendon	0.000	0.998	0.002
D82 Immunodeficiency associated with other major defects	0.001	0.998	0.000
H54.1 Blindness, one eye, low vision, other eye	0.000	0.998	0.001
D59 Acquired haemolytic anaemia	0.001	0.998	0.000
D84 Other immunodeficiencies	0.001	0.998	0.000
D81 Combined immunodeficiencies	0.001	0.998	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.998	0.001
D73.9 Disease of spleen, unspecified	0.001	0.998	0.000
M19.98 Arthrosis, unspecified (Other)	0.001	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.998	0.001
D73.1 Hypersplenism	0.001	0.998	0.000
D86 Sarcoidosis	0.001	0.998	0.001
D80 Immunodeficiency with predominantly antibody defects	0.001	0.998	0.000
D68.8 Other specified coagulation defects	0.001	0.998	0.000
D73.3 Abscess of spleen	0.001	0.998	0.000
D73.2 Chronic congestive splenomegaly	0.001	0.998	0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.001	0.998	0.000
F41.8 Other specified anxiety disorders	0.001	0.998	0.000
G93.8 Other specified disorders of brain	0.000	0.998	0.002
D66 Hereditary factor VIII deficiency	0.001	0.998	0.000
D72 Other disorders of white blood cells	0.001	0.998	0.000
Z80.5 Family history of malignant neoplasm of urinary tract	0.001	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.001	0.998	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.998	0.001
D73.4 Cyst of spleen	0.001	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.998	0.000
D55 Anaemia due to enzyme disorders	0.001	0.998	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.998	0.001
E11.2 With renal complications	0.000	0.998	0.001
E11.1 With ketoacidosis	0.000	0.998	0.001
G93.9 Disorder of brain, unspecified	0.000	0.998	0.001
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.998	0.001
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.001	0.998	0.000
D73.5 Infarction of spleen	0.001	0.998	0.000
H54.7 Unspecified visual loss	0.000	0.998	0.001
H66.9 Otitis media, unspecified	0.001	0.998	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.001	0.998	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.998	0.001
D57 Sickle-cell disorders	0.001	0.998	0.000
D67 Hereditary factor IX deficiency	0.001	0.998	0.000
I61 Intracerebral haemorrhage	0.001	0.998	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.999	0.001
C25.0 Head of pancreas	0.000	0.999	0.001
D59.9 Acquired haemolytic anaemia, unspecified	0.001	0.999	0.000
D59.1 Other autoimmune haemolytic anaemias	0.001	0.999	0.000
D74.9 Methaemoglobinaemia, unspecified	0.001	0.999	0.000
D74.8 Other methaemoglobinaemias	0.001	0.999	0.000
D74.0 Congenital methaemoglobinaemia	0.001	0.999	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.999	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.999	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.999	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.999	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
D75.9 Disease of blood and blood-forming organs, unspecified	0.001	0.999	0.000
D84.8 Other specified immunodeficiencies	0.001	0.999	0.000
D56 Thalassaemia	0.001	0.999	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.001	0.999	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.999	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.999	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.999	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.999	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.999	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.999	0.000
D68 Other coagulation defects	0.001	0.999	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
D58.0 Hereditary spherocytosis	0.001	0.999	0.000
D59.8 Other acquired haemolytic anaemias	0.001	0.999	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.999	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.999	0.000
D59.3 Haemolytic-uraemic syndrome	0.001	0.999	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.999	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.001	0.999	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000
D81.8 Other combined immunodeficiencies	0.001	0.999	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.000
D81.4 Nezelof's syndrome	0.001	0.999	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.000
D82.1 Di George's syndrome	0.001	0.999	0.000
D84.1 Defects in the complement system	0.001	0.999	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.999	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.999	0.001
D70 Agranulocytosis	0.001	0.999	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.001	0.999	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.001	0.999	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations