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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0282
log Bayes Factor = 38.0098
contains 3 variants:
rs6537293
lBF = 12.056
Chr 4 : 145,479,761
rs67455183
lBF = 5.504
Chr 8 : 10,145,925
rs938682
lBF = 19.630
Chr15 : 78,896,547
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J43.9 Emphysema, unspecified
0.000 0.000 1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.000 1.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.000 1.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
J43 Emphysema
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
J43.2 Centrilobular emphysema
0.000 0.077 0.923
J42 Unspecified chronic bronchitis
0.000 0.079 0.921
J46 Status asthmaticus
0.000 0.157 0.843
J43.8 Other emphysema
0.000 0.192 0.808
I74 Arterial embolism and thrombosis
0.000 0.263 0.737
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.264 0.736
J41 Simple and mucopurulent chronic bronchitis
0.000 0.273 0.727
I70 Atherosclerosis
0.000 0.275 0.725
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.283 0.717
J43.0 MacLeod's syndrome
0.000 0.283 0.717
J43.1 Panlobular emphysema
0.000 0.283 0.717
I72 Other aneurysm
0.000 0.284 0.716
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.290 0.710
I72.0 Aneurysm of carotid artery
0.000 0.304 0.696
I74.5 Embolism and thrombosis of iliac artery
0.000 0.309 0.691
I72.8 Aneurysm of other specified arteries
0.000 0.335 0.665
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.342 0.658
I71 Aortic aneurysm and dissection
0.000 0.358 0.642
I74.8 Embolism and thrombosis of other arteries
0.000 0.368 0.632
J40 Bronchitis, not specified as acute or chronic
0.000 0.372 0.628
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.384 0.616
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.384 0.616
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.388 0.612
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.393 0.607
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.395 0.605
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.395 0.605
I73 Other peripheral vascular diseases
0.000 0.401 0.599
I70.0 Atherosclerosis of aorta
0.000 0.409 0.591
I72.3 Aneurysm of iliac artery
0.000 0.433 0.567
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.434 0.566
I72.9 Aneurysm of unspecified site
0.000 0.434 0.566
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.436 0.564
I73.9 Peripheral vascular disease, unspecified
0.000 0.443 0.557
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.444 0.556
J41.0 Simple chronic bronchitis
0.000 0.468 0.532
J41.1 Mucopurulent chronic bronchitis
0.000 0.479 0.521
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.479 0.521
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.487 0.513
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.487 0.513
I72.1 Aneurysm of artery of upper extremity
0.000 0.487 0.513
I70.8 Atherosclerosis of other arteries
0.000 0.491 0.509
I70.9 Generalised and unspecified atherosclerosis
0.000 0.496 0.504
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.505 0.495
I71.0 Dissection of aorta [any part]
0.000 0.523 0.477
I70.1 Atherosclerosis of renal artery
0.000 0.528 0.471
I73.8 Other specified peripheral vascular diseases
0.000 0.532 0.468
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.540 0.460
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.540 0.460
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.540 0.460
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.558 0.442
I79.1 Aortitis in diseases classified elsewhere
0.000 0.558 0.442
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.571 0.429
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.576 0.424
I77 Other disorders of arteries and arterioles
0.000 0.584 0.416
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.595 0.404
I77.1 Stricture of artery
0.000 0.601 0.399
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.617 0.383
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.633 0.366
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.635 0.365
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.638 0.362
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.640 0.360
I77.2 Rupture of artery
0.000 0.641 0.359
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.647 0.353
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.654 0.346
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.662 0.338
I77.4 Coeliac artery compression syndrome
0.000 0.702 0.298
I77.5 Necrosis of artery
0.000 0.702 0.298
F17.1 Harmful use
0.000 0.707 0.293
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.710 0.289
I72.2 Aneurysm of renal artery
0.001 0.711 0.288
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.714 0.286
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.763 0.237
I77.3 Arterial fibromuscular dysplasia
0.000 0.769 0.230
I77.0 Arteriovenous fistula, acquired
0.000 0.776 0.224
I72.4 Aneurysm of artery of lower extremity
0.000 0.791 0.209
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.813 0.187
F17.2 Dependence syndrome
0.000 0.825 0.175
I78 Diseases of capillaries
0.000 0.825 0.174
J45 Asthma
0.000 0.848 0.152
F17.4 Withdrawal state with delirium
0.000 0.866 0.134
F17.5 Psychotic disorder
0.000 0.866 0.134
F17.6 Amnesic syndrome
0.000 0.866 0.134
F17.7 Residual and late-onset psychotic disorder
0.000 0.866 0.134
F17.8 Other mental and behavioural disorders
0.000 0.866 0.134
F17.9 Unspecified mental and behavioural disorder
0.000 0.872 0.128
F17.3 Withdrawal state
0.000 0.879 0.121
F17.0 Acute intoxication
0.000 0.883 0.117
I78.9 Disease of capillaries, unspecified
0.000 0.885 0.115
J45.8 Mixed asthma
0.000 0.888 0.112
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.890 0.110
J45.1 Nonallergic asthma
0.000 0.903 0.097
S32.00 Fracture of lumbar vertebra (closed)
0.091 0.909 0.000
I73.0 Raynaud's syndrome
0.000 0.911 0.089
I78.8 Other diseases of capillaries
0.000 0.913 0.086
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.920 0.080
I60-I69 Cerebrovascular diseases
0.000 0.930 0.070
I60 Subarachnoid haemorrhage
0.000 0.932 0.068
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.935 0.065
I60.8 Other subarachnoid haemorrhage
0.000 0.935 0.065
I77.8 Other specified disorders of arteries and arterioles
0.000 0.936 0.064
I62 Other nontraumatic intracranial haemorrhage
0.000 0.938 0.062
I61 Intracerebral haemorrhage
0.000 0.942 0.058
I69 Sequelae of cerebrovascular disease
0.000 0.942 0.058
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.943 0.057
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.943 0.057
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.943 0.057
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.946 0.054
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.946 0.054
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.947 0.053
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.949 0.051
I69.3 Sequelae of cerebral infarction
0.000 0.949 0.051
I67 Other cerebrovascular diseases
0.000 0.950 0.050
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.950 0.050
I77.6 Arteritis, unspecified
0.000 0.950 0.050
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.951 0.049
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.951 0.049
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.952 0.048
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.955 0.045
I67.9 Cerebrovascular disease, unspecified
0.000 0.956 0.044
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.957 0.043
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.957 0.043
I61.8 Other intracerebral haemorrhage
0.000 0.958 0.042
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.959 0.040
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.960 0.040
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.961 0.039
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.961 0.039
S32.0 Fracture of lumbar vertebra
0.039 0.961 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.962 0.038
I67.3 Progressive vascular leukoencephalopathy
0.000 0.964 0.036
I67.4 Hypertensive encephalopathy
0.000 0.964 0.036
I67.5 Moyamoya disease
0.000 0.964 0.036
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.964 0.036
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.964 0.036
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.964 0.036
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.964 0.036
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.964 0.036
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.964 0.036
I68.0 Cerebral amyloid angiopathy
0.000 0.964 0.035
Chapter IX Diseases of the circulatory system
0.000 0.966 0.034
E21.0 Primary hyperparathyroidism
0.000 0.967 0.033
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.033 0.967 0.000
I67.8 Other specified cerebrovascular diseases
0.000 0.967 0.033
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.967 0.033
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.968 0.032
I78.1 Naevus, nonneoplastic
0.000 0.968 0.032
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.970 0.030
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.970 0.029
I63 Cerebral infarction
0.000 0.971 0.029
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.971 0.028
I67.1 Cerebral aneurysm, nonruptured
0.000 0.971 0.029
I62.1 Nontraumatic extradural haemorrhage
0.000 0.971 0.028
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.972 0.028
S32.01 Fracture of lumbar vertebra (open)
0.028 0.972 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.972 0.028
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.972 0.027
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.972 0.027
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.972 0.027
M88.9 Paget's disease of bone, unspecified
0.027 0.973 0.000
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.974 0.026
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.975 0.025
J93.1 Other spontaneous pneumothorax
0.000 0.975 0.025
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.976 0.024
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.976 0.024
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.976 0.024
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)
0.023 0.977 0.000
I67.2 Cerebral atherosclerosis
0.000 0.977 0.023
I00-I02 Acute rheumatic fever
0.000 0.977 0.022
J47 Bronchiectasis
0.000 0.978 0.022
M88.99 Paget's disease of bone, unspecified (Site unspecified)
0.021 0.979 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.979 0.021
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.979 0.021
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.979 0.021
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.979 0.021
M88.91 Paget's disease of bone, unspecified (Shoulder region)
0.020 0.980 0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)
0.020 0.980 0.000
M88.93 Paget's disease of bone, unspecified (Forearm)
0.020 0.980 0.000
M88.94 Paget's disease of bone, unspecified (Hand)
0.020 0.980 0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)
0.020 0.980 0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)
0.020 0.980 0.000
M88.98 Paget's disease of bone, unspecified (Other)
0.020 0.980 0.000
E24 Cushing's syndrome
0.000 0.980 0.020
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.981 0.019
E20-E35 Disorders of other endocrine glands
0.000 0.981 0.019
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.981 0.019
E24.9 Cushing's syndrome, unspecified
0.000 0.981 0.019
E23 Hypofunction and other disorders of pituitary gland
0.000 0.982 0.018
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.983 0.017
E23.7 Disorder of pituitary gland, unspecified
0.000 0.983 0.017
E20 Hypoparathyroidism
0.000 0.983 0.017
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.983 0.017
E24.0 Pituitary-dependent Cushing's disease
0.000 0.983 0.017
E29 Testicular dysfunction
0.000 0.983 0.017
I01 Rheumatic fever with heart involvement
0.000 0.983 0.016
I02 Rheumatic chorea
0.000 0.983 0.016
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.984 0.016
E23.2 Diabetes insipidus
0.000 0.984 0.016
E22 Hyperfunction of pituitary gland
0.000 0.984 0.016
M88 Paget's disease of bone [osteitis deformans]
0.016 0.984 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.984 0.016
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.984 0.015
E20.9 Hypoparathyroidism, unspecified
0.000 0.985 0.015
E29.1 Testicular hypofunction
0.000 0.985 0.015
E23.6 Other disorders of pituitary gland
0.000 0.985 0.015
I00 Rheumatic fever without mention of heart involvement
0.000 0.985 0.014
I65.1 Occlusion and stenosis of basilar artery
0.000 0.985 0.014
E24.2 Drug-induced Cushing's syndrome
0.000 0.985 0.014
E21.4 Other specified disorders of parathyroid gland
0.000 0.986 0.014
E24.1 Nelson's syndrome
0.000 0.986 0.014
E24.3 Ectopic ACTH syndrome
0.000 0.986 0.014
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.986 0.014
E24.8 Other Cushing's syndrome
0.000 0.986 0.014
E30 Disorders of puberty, not elsewhere classified
0.000 0.986 0.014
E32 Diseases of thymus
0.000 0.986 0.014
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.986 0.014
E31 Polyglandular dysfunction
0.000 0.986 0.014
E21.2 Other hyperparathyroidism
0.000 0.987 0.013
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.987 0.013
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.987 0.013
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.987 0.013
E23.1 Drug-induced hypopituitarism
0.000 0.987 0.013
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.987 0.013
E26 Hyperaldosteronism
0.000 0.987 0.013
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.987 0.012
E27 Other disorders of adrenal gland
0.000 0.987 0.013
E20.0 Idiopathic hypoparathyroidism
0.000 0.988 0.012
E20.1 Pseudohypoparathyroidism
0.000 0.988 0.012
E20.8 Other hypoparathyroidism
0.000 0.988 0.012
M88.0 Paget's disease of skull
0.012 0.988 0.000
E29.0 Testicular hyperfunction
0.000 0.988 0.012
E29.8 Other testicular dysfunction
0.000 0.988 0.012
I01.0 Acute rheumatic pericarditis
0.000 0.988 0.012
I01.1 Acute rheumatic endocarditis
0.000 0.988 0.012
I01.2 Acute rheumatic myocarditis
0.000 0.988 0.012
I01.8 Other acute rheumatic heart disease
0.000 0.988 0.012
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.988 0.012
I02.0 Rheumatic chorea with heart involvement
0.000 0.988 0.012
I02.9 Rheumatic chorea without heart involvement
0.000 0.988 0.012
E22.1 Hyperprolactinaemia
0.000 0.988 0.012
Z99.8 Dependence on other enabling machines and devices
0.000 0.988 0.012
M88.8 Paget's disease of other bones
0.012 0.988 0.000
E25 Adrenogenital disorders
0.000 0.988 0.012
E28 Ovarian dysfunction
0.000 0.988 0.012
E22.8 Other hyperfunction of pituitary gland
0.000 0.988 0.012
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.988 0.012
E29.9 Testicular dysfunction, unspecified
0.000 0.988 0.011
E22.0 Acromegaly and pituitary gigantism
0.000 0.988 0.012
E27.2 Addisonian crisis
0.000 0.989 0.011
E30.0 Delayed puberty
0.000 0.990 0.010
E30.1 Precocious puberty
0.000 0.990 0.010
E30.8 Other disorders of puberty
0.000 0.990 0.010
E30.9 Disorder of puberty, unspecified
0.000 0.990 0.010
E32.0 Persistent hyperplasia of thymus
0.000 0.990 0.010
E32.1 Abscess of thymus
0.000 0.990 0.010
E32.8 Other diseases of thymus
0.000 0.990 0.010
E32.9 Disease of thymus, unspecified
0.000 0.990 0.010
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.990 0.010
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.990 0.010
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.990 0.010
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.990 0.010
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.990 0.010
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.990 0.010
K35.1 Acute appendicitis with peritoneal abscess
0.010 0.990 0.000
E31.1 Polyglandular hyperfunction
0.000 0.990 0.010
E31.8 Other polyglandular dysfunction
0.000 0.990 0.010
E31.9 Polyglandular dysfunction, unspecified
0.000 0.990 0.010
I63.8 Other cerebral infarction
0.000 0.990 0.010
E28.3 Primary ovarian failure
0.000 0.990 0.010
I05-I09 Chronic rheumatic heart diseases
0.000 0.990 0.010
M88.00 Paget's disease of skull-Mult sites
0.009 0.990 0.000
E26.1 Secondary hyperaldosteronism
0.000 0.990 0.009
E26.8 Other hyperaldosteronism
0.000 0.990 0.009
E31.0 Autoimmune polyglandular failure
0.000 0.990 0.009
E34 Other endocrine disorders
0.000 0.991 0.009
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.000 0.991 0.009
E27.0 Other adrenocortical overactivity
0.000 0.991 0.009
E27.5 Adrenomedullary hyperfunction
0.000 0.991 0.009
E26.9 Hyperaldosteronism, unspecified
0.000 0.991 0.009
M88.85 Paget's disease of other bones (Pelvic region and thigh)
0.009 0.991 0.000
M88.01 Paget's disease of skull-Shldr region
0.009 0.991 0.000
M88.02 Paget's disease of skull-Upper arm
0.009 0.991 0.000
M88.03 Paget's disease of skull-Forearm
0.009 0.991 0.000
M88.04 Paget's disease of skull-Hand
0.009 0.991 0.000
M88.05 Paget's disease of skull-Pelvic/Thigh
0.009 0.991 0.000
M88.06 Paget's disease of skull-Lower Leg
0.009 0.991 0.000
M88.07 Paget's disease of skull-Ankle/Foot
0.009 0.991 0.000
M88.08 Paget's disease of skull-Other
0.009 0.991 0.000
M88.09 Paget's disease of skull-Site unspec
0.009 0.991 0.000
E26.0 Primary hyperaldosteronism
0.000 0.991 0.009
M88.80 Paget's disease of other bones (Multiple sites)
0.009 0.991 0.000
M88.81 Paget's disease of other bones (Shoulder region)
0.009 0.991 0.000
M88.82 Paget's disease of other bones (Upper arm)
0.009 0.991 0.000
M88.83 Paget's disease of other bones (Forearm)
0.009 0.991 0.000
M88.84 Paget's disease of other bones (Hand)
0.009 0.991 0.000
M88.86 Paget's disease of other bones (Lower leg)
0.009 0.991 0.000
M88.87 Paget's disease of other bones (Ankle and foot)
0.009 0.991 0.000
M88.88 Paget's disease of other bones (Other)
0.009 0.991 0.000
M88.89 Paget's disease of other bones (Site unspecified)
0.009 0.991 0.000
C25.0 Head of pancreas
0.000 0.991 0.009
E25.8 Other adrenogenital disorders
0.000 0.991 0.009
E25.9 Adrenogenital disorder, unspecified
0.000 0.991 0.009
E28.0 Oestrogen excess
0.000 0.991 0.009
E28.1 Androgen excess
0.000 0.991 0.009
E28.8 Other ovarian dysfunction
0.000 0.991 0.009
E28.9 Ovarian dysfunction, unspecified
0.000 0.991 0.009
J45.0 Predominantly allergic asthma
0.000 0.991 0.009
M79.84 Other specified soft tissue disorders (Hand)
0.000 0.992 0.008
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.992 0.008
C77.8 Lymph nodes of multiple regions
0.008 0.992 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.992 0.008
I09 Other rheumatic heart diseases
0.000 0.992 0.008
E34.0 Carcinoid syndrome
0.000 0.992 0.008
S12.70 Multiple fractures of cervical spine (closed)
0.000 0.992 0.008
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.000 0.992 0.007
E34.3 Short stature, not elsewhere classified
0.000 0.993 0.007
I26 Pulmonary embolism
0.000 0.993 0.007
E34.1 Other hypersecretion of intestinal hormones
0.000 0.993 0.007
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.993 0.007
E34.4 Constitutional tall stature
0.000 0.993 0.007
E34.5 Androgen resistance syndrome
0.000 0.993 0.007
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.000 0.993 0.007
F16 Mental and behavioural disorders due to use of hallucinogens
0.000 0.993 0.007
F18 Mental and behavioural disorders due to use of volatile solvents
0.000 0.993 0.007
I06 Rheumatic aortic valve diseases
0.000 0.993 0.007
I09.9 Rheumatic heart disease, unspecified
0.000 0.993 0.007
F14 Mental and behavioural disorders due to use of cocaine
0.000 0.993 0.007
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.993 0.007
S12.90 Fracture of neck, part unspecified (closed)
0.000 0.993 0.007
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.993 0.006
I05 Rheumatic mitral valve diseases
0.000 0.994 0.006
I05.1 Rheumatic mitral insufficiency
0.000 0.994 0.006
E21.3 Hyperparathyroidism, unspecified
0.000 0.994 0.006
F15.1 Harmful use
0.000 0.994 0.006
M47.87 Other spondylosis (Lumbosacral region)
0.000 0.994 0.006
S12.7 Multiple fractures of cervical spine
0.000 0.994 0.006
F19.2 Dependence syndrome
0.000 0.994 0.006
I99 Other and unspecified disorders of circulatory system
0.000 0.994 0.006
I09.0 Rheumatic myocarditis
0.000 0.994 0.006
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.994 0.006
I09.2 Chronic rheumatic pericarditis
0.000 0.994 0.006
I09.8 Other specified rheumatic heart diseases
0.000 0.994 0.006
Q63.0 Accessory kidney
0.000 0.994 0.006
E27.9 Disorder of adrenal gland, unspecified
0.000 0.994 0.006
O69.2 Labour and delivery complicated by other cord entanglement
0.000 0.994 0.006
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.000 0.994 0.006
E27.1 Primary adrenocortical insufficiency
0.000 0.994 0.006
F15.0 Acute intoxication
0.000 0.994 0.005
F15.2 Dependence syndrome
0.000 0.994 0.005
F15.3 Withdrawal state
0.000 0.994 0.005
F15.4 Withdrawal state with delirium
0.000 0.994 0.005
F15.5 Psychotic disorder
0.000 0.994 0.005
F15.6 Amnesic syndrome
0.000 0.994 0.005
F15.7 Residual and late-onset psychotic disorder
0.000 0.994 0.005
F15.8 Other mental and behavioural disorders
0.000 0.994 0.005
F15.9 Unspecified mental and behavioural disorder
0.000 0.994 0.005
S12.9 Fracture of neck, part unspecified
0.000 0.994 0.006
Q87.4 Marfan's syndrome
0.000 0.994 0.006
I28 Other diseases of pulmonary vessels
0.000 0.994 0.005
F19.0 Acute intoxication
0.000 0.995 0.005
F19.3 Withdrawal state
0.000 0.995 0.005
F19.4 Withdrawal state with delirium
0.000 0.995 0.005
F19.5 Psychotic disorder
0.000 0.995 0.005
F19.6 Amnesic syndrome
0.000 0.995 0.005
F19.7 Residual and late-onset psychotic disorder
0.000 0.995 0.005
F19.8 Other mental and behavioural disorders
0.000 0.995 0.005
F19.9 Unspecified mental and behavioural disorder
0.000 0.995 0.005
M86-M90 Other osteopathies
0.005 0.995 0.000
F16.0 Acute intoxication
0.000 0.995 0.005
F16.1 Harmful use
0.000 0.995 0.005
F16.2 Dependence syndrome
0.000 0.995 0.005
F16.3 Withdrawal state
0.000 0.995 0.005
F16.4 Withdrawal state with delirium
0.000 0.995 0.005
F16.5 Psychotic disorder
0.000 0.995 0.005
F16.6 Amnesic syndrome
0.000 0.995 0.005
F16.7 Residual and late-onset psychotic disorder
0.000 0.995 0.005
F16.8 Other mental and behavioural disorders
0.000 0.995 0.005
F16.9 Unspecified mental and behavioural disorder
0.000 0.995 0.005
F18.0 Acute intoxication
0.000 0.995 0.005
F18.1 Harmful use
0.000 0.995 0.005
F18.2 Dependence syndrome
0.000 0.995 0.005
F18.3 Withdrawal state
0.000 0.995 0.005
F18.4 Withdrawal state with delirium
0.000 0.995 0.005
F18.5 Psychotic disorder
0.000 0.995 0.005
F18.6 Amnesic syndrome
0.000 0.995 0.005
F18.7 Residual and late-onset psychotic disorder
0.000 0.995 0.005
F18.8 Other mental and behavioural disorders
0.000 0.995 0.005
F18.9 Unspecified mental and behavioural disorder
0.000 0.995 0.005
I06.1 Rheumatic aortic insufficiency
0.000 0.995 0.005
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.995 0.005
I06.8 Other rheumatic aortic valve diseases
0.000 0.995 0.005
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.995 0.005
F14.0 Acute intoxication
0.000 0.995 0.005
F14.2 Dependence syndrome
0.000 0.995 0.005
F14.3 Withdrawal state
0.000 0.995 0.005
F14.4 Withdrawal state with delirium
0.000 0.995 0.005
F14.5 Psychotic disorder
0.000 0.995 0.005
F14.6 Amnesic syndrome
0.000 0.995 0.005
F14.7 Residual and late-onset psychotic disorder
0.000 0.995 0.005
F14.8 Other mental and behavioural disorders
0.000 0.995 0.005
F14.9 Unspecified mental and behavioural disorder
0.000 0.995 0.005
F12 Mental and behavioural disorders due to use of cannabinoids
0.000 0.995 0.005
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.995 0.005
M13.91 Arthritis, unspecified (Shoulder region)
0.000 0.995 0.005
F14.1 Harmful use
0.000 0.995 0.005
S12 Fracture of neck
0.000 0.995 0.005
I06.0 Rheumatic aortic stenosis
0.000 0.995 0.005
M86.9 Osteomyelitis, unspecified
0.003 0.995 0.002
G37.9 Demyelinating disease of central nervous system, unspecified
0.005 0.995 0.000
M89 Other disorders of bone
0.005 0.995 0.000
C67.3 Anterior wall of bladder
0.000 0.995 0.005
C18.3 Hepatic flexure
0.000 0.995 0.005
R47.1 Dysarthria and anarthria
0.000 0.995 0.005
E34.8 Other specified endocrine disorders
0.000 0.995 0.004
S12.71 Multiple fractures of cervical spine (open)
0.000 0.995 0.004
C67.2 Lateral wall of bladder
0.000 0.995 0.005
N34.2 Other urethritis
0.005 0.995 0.000
C67.6 Ureteric orifice
0.000 0.995 0.005
M89.81 Other specified disorders of bone (Shoulder region)
0.005 0.995 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.995 0.004
M89.9 Disorder of bone, unspecified
0.005 0.995 0.000
I05.8 Other mitral valve diseases
0.000 0.995 0.004
M89.94 Disorder of bone, unspecified (Hand)
0.004 0.995 0.000
F13.0 Acute intoxication
0.000 0.996 0.004
F13.1 Harmful use
0.000 0.996 0.004
F13.4 Withdrawal state with delirium
0.000 0.996 0.004
F13.5 Psychotic disorder
0.000 0.996 0.004
F13.6 Amnesic syndrome
0.000 0.996 0.004
F13.7 Residual and late-onset psychotic disorder
0.000 0.996 0.004
F13.8 Other mental and behavioural disorders
0.000 0.996 0.004
F13.9 Unspecified mental and behavioural disorder
0.000 0.996 0.004
M86 Osteomyelitis
0.004 0.996 0.001
I05.0 Mitral stenosis
0.000 0.996 0.004
M89.91 Disorder of bone, unspecified (Shoulder region)
0.004 0.996 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.996 0.004
S12.91 Fracture of neck, part unspecified (open)
0.000 0.996 0.004
I07 Rheumatic tricuspid valve diseases
0.000 0.996 0.004
F19.1 Harmful use
0.000 0.996 0.004
I05.2 Mitral stenosis with insufficiency
0.000 0.996 0.004
E34.9 Endocrine disorder, unspecified
0.000 0.996 0.004
I28.1 Aneurysm of pulmonary artery
0.000 0.996 0.004
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.996 0.004
M89.0 Algoneurodystrophy
0.004 0.996 0.000
F13.3 Withdrawal state
0.000 0.996 0.004
S12.1 Fracture of second cervical vertebra
0.000 0.996 0.004
M89.96 Disorder of bone, unspecified (Lower leg)
0.004 0.996 0.000
F12.0 Acute intoxication
0.000 0.996 0.004
F12.3 Withdrawal state
0.000 0.996 0.004
F12.4 Withdrawal state with delirium
0.000 0.996 0.004
F12.5 Psychotic disorder
0.000 0.996 0.004
F12.6 Amnesic syndrome
0.000 0.996 0.004
F12.7 Residual and late-onset psychotic disorder
0.000 0.996 0.004
F12.8 Other mental and behavioural disorders
0.000 0.996 0.004
F12.9 Unspecified mental and behavioural disorder
0.000 0.996 0.004
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.996 0.004
I98.0 Cardiovascular syphilis
0.000 0.996 0.004
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.996 0.004
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.996 0.004
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.003 0.996 0.001
M41.99 Scoliosis, unspecified (Site unspecified)
0.004 0.996 0.000
M89.8 Other specified disorders of bone
0.004 0.996 0.000
S12.8 Fracture of other parts of neck
0.000 0.996 0.004
F11 Mental and behavioural disorders due to use of opioids
0.000 0.996 0.004
Q63.1 Lobulated, fused and horseshoe kidney
0.000 0.996 0.004
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.002 0.996 0.001
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.002 0.996 0.001
M86.92 Osteomyelitis, unspecified (Upper arm)
0.002 0.996 0.001
M86.93 Osteomyelitis, unspecified (Forearm)
0.002 0.996 0.001
M40.2 Other and unspecified kyphosis
0.004 0.996 0.000
S12.0 Fracture of first cervical vertebra
0.000 0.996 0.004
B44.1 Other pulmonary aspergillosis
0.004 0.996 0.000
F13.2 Dependence syndrome
0.000 0.996 0.004
M89.3 Hypertrophy of bone
0.004 0.996 0.000
C67 Malignant neoplasm of bladder
0.000 0.996 0.004
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.002 0.996 0.002
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.004 0.996 0.000
M89.1 Epiphyseal arrest
0.004 0.996 0.000
M89.2 Other disorders of bone development and growth
0.004 0.996 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.004 0.996 0.000
M89.6 Osteopathy after poliomyelitis
0.004 0.996 0.000
M89.01 Algoneurodystrophy (Shoulder region)
0.004 0.996 0.000
Q63 Other congenital malformations of kidney
0.000 0.996 0.004
M90 Osteopathies in diseases classified elsewhere
0.004 0.996 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.000 0.996 0.004
M40.26 Other and unspecified kyphosis (Lumbar region)
0.004 0.996 0.000
S90.0 Contusion of ankle
0.004 0.996 0.000
J93 Pneumothorax
0.000 0.996 0.004
M86.96 Osteomyelitis, unspecified (Lower leg)
0.003 0.996 0.001
M86.94 Osteomyelitis, unspecified (Hand)
0.003 0.996 0.001
D46.9 Myelodysplastic syndrome, unspecified
0.004 0.996 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.000 0.996 0.004
M89.03 Algoneurodystrophy (Forearm)
0.004 0.996 0.000
M40.5 Lordosis, unspecified
0.004 0.996 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.996 0.004
M40 Kyphosis and lordosis
0.004 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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