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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Diagnostic term associations

Hospitalization Episode Statistics (HES)

I06.1
Rheumatic aortic insufficiency
Parent term
I06 Rheumatic aortic valve diseases
What are diagnostic terms?
Variant effects

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
rs56131196 lBF = 198.195   Chr19 : 45,422,846
0.742 0.258 0.000
rs4420638 lBF = 199.322   Chr19 : 45,422,946
0.733 0.267 0.000
rs115049412 lBF = 15.9663   Chr2 : 200,960,006
0.695 0.304 0.000
rs111724274 lBF = 36.4129   Chr2 : 200,713,124
0.667 0.333 0.000
rs12903285 lBF = 23.1095   Chr15 : 78,778,953
0.643 0.357 0.000
rs12899351 lBF = 23.481   Chr15 : 78,792,398
0.609 0.390 0.000
rs8042260 lBF = 23.6429   Chr15 : 78,774,374
0.608 0.392 0.000
rs12910910 lBF = 23.6547   Chr15 : 78,767,850
0.608 0.392 0.000
rs12916801 lBF = 23.5612   Chr15 : 78,769,130
0.607 0.393 0.000
rs8043227 lBF = 23.5612   Chr15 : 78,768,871
0.607 0.393 0.000
rs4887059 lBF = 23.2298   Chr15 : 78,782,095
0.605 0.394 0.000
rs505922 lBF = 162.562   Chr9 : 136,149,229
0.605 0.394 0.000
rs965604 lBF = 23.272   Chr15 : 78,789,223
0.605 0.395 0.000
rs12594711 lBF = 23.1532   Chr15 : 78,793,921
0.605 0.395 0.000
rs36146269 lBF = 23.2878   Chr15 : 78,779,510
0.605 0.395 0.000
rs1504549 lBF = 23.3155   Chr15 : 78,766,629
0.604 0.396 0.000
rs4362358 lBF = 23.1905   Chr15 : 78,796,104
0.604 0.396 0.000
rs4299116 lBF = 23.1218   Chr15 : 78,766,194
0.603 0.397 0.000
rs55634267 lBF = 6.28387   Chr17 : 47,283,815
0.603 0.397 0.000
rs12593229 lBF = 23.234   Chr15 : 78,765,290
0.603 0.397 0.000
rs12904234 lBF = 23.0302   Chr15 : 78,779,384
0.602 0.398 0.000
rs12903295 lBF = 23.0086   Chr15 : 78,778,972
0.601 0.399 0.000
rs612169 lBF = 158.629   Chr9 : 136,143,442
0.597 0.403 0.000
rs11637656 lBF = 23.7386   Chr15 : 78,751,961
0.596 0.404 0.000
rs1448817 lBF = 50.4126   Chr4 : 111,641,053
0.594 0.406 0.000
rs3094157 lBF = 54.2952   Chr6 : 29,836,239
0.590 0.410 0.000
rs687621 lBF = 157.152   Chr9 : 136,137,065
0.587 0.413 0.000
rs2215614 lBF = 7.56312   Chr7 : 35,277,093
0.000 0.416 0.584
rs514659 lBF = 140.82   Chr9 : 136,142,203
0.581 0.419 0.000
rs643434 lBF = 151.434   Chr9 : 136,142,355
0.581 0.419 0.000
rs8176719 lBF = 148.272   Chr9 : 136,132,908
0.580 0.420 0.000
rs73099187 lBF = 9.66779   Chr7 : 35,291,491
0.000 0.424 0.576
rs657152 lBF = 149.847   Chr9 : 136,139,265
0.569 0.431 0.000
rs1632984 lBF = 54.2695   Chr6 : 29,773,392
0.568 0.432 0.000
rs79215950 lBF = 8.20907   Chr7 : 35,277,067
0.000 0.433 0.567
rs2743931 lBF = 53.7657   Chr6 : 29,787,072
0.560 0.440 0.000
rs429358 lBF = 222.835   Chr19 : 45,411,941
0.558 0.442 0.000
rs11205277 lBF = 2.49265   Chr1 : 149,892,872
0.557 0.442 0.000
rs12940887 lBF = 28.7338   Chr17 : 47,402,807
0.556 0.444 0.000
rs1233330 lBF = 54.1314   Chr6 : 29,799,103
0.553 0.447 0.000
rs2845885 lBF = 4.30722   Chr11 : 63,869,062
0.000 0.451 0.549
rs10490871 lBF = 6.36422   Chr3 : 35,667,761
0.546 0.454 0.000
rs4949223 lBF = 10.3921   Chr1 : 32,221,913
0.542 0.457 0.000
rs1169314 lBF = 9.37742   Chr12 : 121,443,116
0.541 0.459 0.000
rs12592111 lBF = 20.7266   Chr15 : 78,767,346
0.539 0.461 0.000
rs59007384 lBF = 103.247   Chr19 : 45,396,665
0.537 0.463 0.000
rs241438 lBF = 109.368   Chr6 : 32,797,620
0.534 0.466 0.000
rs16948048 lBF = 28.5777   Chr17 : 47,440,466
0.533 0.466 0.000
rs114344942 lBF = 24.8284   Chr6 : 34,207,990
0.533 0.467 0.000
rs241439 lBF = 96.0758   Chr6 : 32,797,537
0.532 0.468 0.000
rs204994 lBF = 75.1027   Chr6 : 32,154,998
0.531 0.469 0.000
rs204992 lBF = 357.269   Chr6 : 32,156,908
0.531 0.469 0.000
rs241437 lBF = 93.8533   Chr6 : 32,797,684
0.529 0.470 0.000
rs204993 lBF = 249.805   Chr6 : 32,155,581
0.529 0.471 0.000
rs769449 lBF = 166.029   Chr19 : 45,410,002
0.526 0.474 0.000
rs663576 lBF = 16.6236   Chr17 : 47,331,987
0.526 0.474 0.000
rs2264750 lBF = 9.22565   Chr12 : 121,450,165
0.526 0.474 0.000
rs4949465 lBF = 13.4685   Chr1 : 32,178,489
0.519 0.480 0.000
rs204995 lBF = 73.8651   Chr6 : 32,154,285
0.518 0.482 0.000
rs1632971 lBF = 54.1062   Chr6 : 29,777,911
0.516 0.484 0.000
rs115957279 lBF = 12.0137   Chr4 : 111,033,474
0.515 0.485 0.000
rs6843082 lBF = 86.0876   Chr4 : 111,718,067
0.514 0.486 0.000
rs2200733 lBF = 66.0925   Chr4 : 111,710,169
0.513 0.487 0.000
rs75904186 lBF = 8.14526   Chr18 : 38,656,975
0.513 0.487 0.000
rs12646447 lBF = 65.8464   Chr4 : 111,699,326
0.513 0.487 0.000
rs612260 lBF = 9.02876   Chr18 : 38,534,894
0.513 0.487 0.000
rs6817105 lBF = 64.6903   Chr4 : 111,705,768
0.513 0.487 0.000
rs17042171 lBF = 64.7702   Chr4 : 111,708,287
0.513 0.487 0.000
rs1899875 lBF = 15.3034   Chr21 : 22,669,522
0.513 0.487 0.000
rs2286251 lBF = 14.6643   Chr7 : 107,702,877
0.512 0.488 0.000
rs62424573 lBF = 10.2915   Chr6 : 62,235,412
0.512 0.488 0.000
rs28613901 lBF = 12.234   Chr22 : 45,260,956
0.512 0.488 0.000
rs17042081 lBF = 59.9223   Chr4 : 111,653,211
0.511 0.488 0.000
rs34242703 lBF = 10.2176   Chr22 : 45,225,346
0.511 0.488 0.000
rs12209307 lBF = 5.28684   Chr6 : 95,418,039
0.511 0.489 0.000
rs2039631 lBF = 5.35076   Chr1 : 9,068,020
0.511 0.489 0.000
rs34282046 lBF = 10.8372   Chr19 : 19,304,899
0.510 0.490 0.000
rs79565709 lBF = 12.3505   Chr19 : 40,832,132
0.510 0.490 0.000
rs869708 lBF = 14.092   Chr21 : 46,434,954
0.510 0.490 0.000
rs75397367 lBF = 8.07931   Chr16 : 84,041,217
0.510 0.490 0.000
rs13154291 lBF = 12.6575   Chr5 : 160,443,509
0.510 0.490 0.000
rs76194019 lBF = 13.1316   Chr11 : 8,338,131
0.510 0.490 0.000
rs7170930 lBF = 4.48048   Chr15 : 66,580,853
0.509 0.490 0.000
rs80184685 lBF = 12.8291   Chr11 : 3,142,769
0.509 0.491 0.000
rs75021220 lBF = 47.1082   Chr4 : 111,658,394
0.508 0.492 0.000
rs79490353 lBF = 11.9496   Chr13 : 28,623,048
0.508 0.492 0.000
rs3213545 lBF = 7.8099   Chr12 : 121,471,337
0.508 0.492 0.000
rs11864146 lBF = 7.6214   Chr16 : 84,046,715
0.508 0.492 0.000
rs185572712 lBF = 6.25461   Chr5 : 60,173,515
0.507 0.492 0.000
rs507666 lBF = 152.361   Chr9 : 136,149,399
0.507 0.493 0.000
rs76733568 lBF = 27.8026   Chr9 : 24,659,540
0.507 0.493 0.000
rs11232369 lBF = 8.62097   Chr11 : 80,562,738
0.507 0.493 0.000
rs117242132 lBF = 21.0067   Chr18 : 45,672,152
0.507 0.493 0.000
rs77268492 lBF = 15.5722   Chr10 : 95,315,221
0.507 0.493 0.000
rs13215574 lBF = 14.0292   Chr6 : 146,006,127
0.506 0.493 0.000
rs117151396 lBF = 15.1715   Chr20 : 17,934,882
0.506 0.494 0.000
rs80201289 lBF = 8.47932   Chr7 : 150,957,474
0.506 0.494 0.000
rs17710883 lBF = 12.3438   Chr1 : 214,104,347
0.506 0.494 0.000
rs117937738 lBF = 12.6854   Chr11 : 129,503,398
0.506 0.494 0.000
rs10232743 lBF = 7.28409   Chr7 : 43,910,882
0.505 0.494 0.000
rs41283728 lBF = 15.7405   Chr10 : 29,136,175
0.505 0.495 0.000
rs9531710 lBF = 11.0604   Chr13 : 85,686,069
0.505 0.495 0.000
rs12370770 lBF = 24.384   Chr12 : 112,277,084
0.505 0.495 0.000
rs75957893 lBF = 8.17006   Chr16 : 75,381,816
0.505 0.495 0.000
rs78798473 lBF = 19.9784   Chr4 : 1,669,252
0.504 0.496 0.000
rs12779371 lBF = 7.9231   Chr10 : 76,256,536
0.504 0.496 0.000
rs181319480 lBF = 9.5655   Chr3 : 58,793,057
0.504 0.496 0.000
rs176095 lBF = 360.117   Chr6 : 32,158,319
0.504 0.496 0.000
rs62328524 lBF = 13.1701   Chr4 : 161,682,941
0.504 0.496 0.000
rs117597017 lBF = 9.81246   Chr14 : 56,885,357
0.504 0.496 0.000
rs157582 lBF = 98.5206   Chr19 : 45,396,219
0.504 0.496 0.000
rs35836525 lBF = 18.108   Chr2 : 97,601,693
0.503 0.497 0.000
rs117933286 lBF = 14.503   Chr9 : 81,306,530
0.503 0.497 0.000
rs79837333 lBF = 19.6803   Chr5 : 80,512,632
0.503 0.497 0.000
rs114450019 lBF = 13.3669   Chr1 : 185,420,876
0.502 0.498 0.000
rs79343817 lBF = 15.2744   Chr10 : 71,822,901
0.502 0.498 0.000
rs79851078 lBF = 5.58339   Chr17 : 30,005,058
0.502 0.498 0.000
rs78614307 lBF = 12.2775   Chr19 : 5,790,540
0.502 0.498 0.000
rs73114499 lBF = 8.70598   Chr7 : 38,967,240
0.501 0.498 0.000
rs117091812 lBF = 12.7428   Chr9 : 81,272,613
0.501 0.499 0.000
rs74859699 lBF = 18.3331   Chr1 : 154,739,875
0.501 0.499 0.000
rs73582359 lBF = 18.0266   Chr13 : 104,556,680
0.501 0.499 0.000
rs80213544 lBF = 10.5045   Chr16 : 75,116,252
0.501 0.499 0.000
rs3731249 lBF = 12.0614   Chr9 : 21,970,916
0.501 0.499 0.000
rs28659842 lBF = 12.442   Chr22 : 24,776,451
0.501 0.499 0.000
rs3766823 lBF = 11.995   Chr1 : 32,197,257
0.501 0.499 0.000
rs3128935 lBF = 12.9734   Chr6 : 32,972,404
0.500 0.499 0.000
rs76956704 lBF = 15.02   Chr6 : 152,031,496
0.500 0.500 0.000
rs17162040 lBF = 6.74453   Chr1 : 27,883,227
0.000 0.500 0.500
rs113123495 lBF = 7.90763   Chr19 : 5,587,540
0.499 0.500 0.000
rs76710341 lBF = 11.6968   Chr6 : 93,881,166
0.499 0.500 0.000
rs114987466 lBF = 13.887   Chr1 : 21,632,046
0.499 0.500 0.000
rs12378793 lBF = 6.11146   Chr9 : 79,613,935
0.499 0.501 0.000
rs76157199 lBF = 10.0516   Chr2 : 98,541,874
0.499 0.501 0.000
rs114718455 lBF = 13.0267   Chr3 : 53,464,055
0.499 0.501 0.000
rs73598796 lBF = 12.129   Chr16 : 82,025,794
0.499 0.501 0.000
rs117759827 lBF = 8.85751   Chr9 : 34,400,980
0.498 0.501 0.000
rs7418032 lBF = 19.7409   Chr1 : 195,229,043
0.498 0.502 0.000
rs6857 lBF = 185.788   Chr19 : 45,392,254
0.498 0.502 0.000
Affx-23671264 lBF = 6.33533   Chr4 : 154,094,220
0.498 0.502 0.000
rs74617384 lBF = 405.131   Chr6 : 160,997,118
0.498 0.502 0.000
rs117411365 lBF = 26.5974   Chr18 : 67,468,303
0.498 0.502 0.000
rs13209782 lBF = 23.882   Chr6 : 146,142,384
0.498 0.502 0.000
rs4374681 lBF = 5.49218   Chr4 : 1,566,164
0.497 0.502 0.000
rs73542936 lBF = 11.6477   Chr8 : 1,839,557
0.497 0.502 0.000
rs118148296 lBF = 8.65957   Chr18 : 33,640,579
0.497 0.503 0.000
rs10455872 lBF = 427.757   Chr6 : 161,010,118
0.497 0.503 0.000
rs79767168 lBF = 18.8427   Chr8 : 131,516,058
0.497 0.503 0.000
Affx-28471757 lBF = 171.957   Chr6 : 32,313,659
0.496 0.504 0.000
rs75729340 lBF = 21.0937   Chr18 : 31,480,742
0.496 0.504 0.000
rs60164086 lBF = 8.49074   Chr19 : 19,300,192
0.496 0.504 0.000
rs635634 lBF = 144.118   Chr9 : 136,155,000
0.496 0.504 0.000
rs55730499 lBF = 430.193   Chr6 : 161,005,610
0.495 0.504 0.000
rs111409535 lBF = 18.5218   Chr21 : 30,790,390
0.495 0.505 0.000
rs11752591 lBF = 9.67572   Chr6 : 91,507,965
0.495 0.505 0.000
rs76335573 lBF = 12.4927   Chr1 : 107,687,605
0.495 0.505 0.000
rs2792760 lBF = 12.7806   Chr10 : 113,850,024
0.494 0.505 0.000
rs117930276 lBF = 8.79467   Chr14 : 68,864,686
0.494 0.505 0.000
rs79434560 lBF = 18.5118   Chr15 : 67,049,150
0.494 0.506 0.000
rs8044050 lBF = 16.7322   Chr16 : 74,922,857
0.494 0.506 0.000
rs13061465 lBF = 14.9946   Chr3 : 72,568,369
0.494 0.506 0.000
Affx-36746018 lBF = 11.8469   Chr4 : 6,126,993
0.494 0.506 0.000
rs114889417 lBF = 12.566   Chr6 : 33,761,049
0.493 0.506 0.000
rs34308307 lBF = 7.33618   Chr21 : 46,620,730
0.493 0.506 0.000
rs34253858 lBF = 17.8124   Chr6 : 146,533,489
0.493 0.507 0.000
rs77169098 lBF = 26.0362   Chr2 : 97,638,495
0.493 0.507 0.000
rs7007 lBF = 7.38981   Chr1 : 151,735,576
0.000 0.507 0.493
rs41308401 lBF = 6.59762   Chr1 : 150,938,877
0.493 0.507 0.000
rs80237806 lBF = 12.8825   Chr5 : 176,728,878
0.493 0.507 0.000
rs76276670 lBF = 38.5052   Chr21 : 30,505,980
0.493 0.507 0.000
rs12937634 lBF = 15.2509   Chr17 : 47,444,442
0.493 0.507 0.000
rs75722236 lBF = 23.8887   Chr1 : 98,118,470
0.492 0.507 0.000
rs113173951 lBF = 6.15041   Chr1 : 27,877,418
0.000 0.508 0.492
rs4709408 lBF = 84.0955   Chr6 : 160,625,231
0.492 0.508 0.000
rs34159951 lBF = 19.1998   Chr5 : 45,689,447
0.492 0.508 0.000
rs74320203 lBF = 11.4376   Chr1 : 20,921,903
0.492 0.508 0.000
rs117140019 lBF = 22.4153   Chr17 : 27,396,153
0.492 0.508 0.000
rs73210044 lBF = 15.2486   Chr8 : 13,392,360
0.492 0.508 0.000
rs78643014 lBF = 10.956   Chr5 : 68,403,982
0.492 0.508 0.000
rs74112468 lBF = 12.4362   Chr13 : 90,520,396
0.492 0.508 0.000
rs76521925 lBF = 12.5137   Chr7 : 47,706,389
0.491 0.508 0.000
rs74385618 lBF = 11.915   Chr5 : 62,522,666
0.491 0.508 0.000
rs7277179 lBF = 15.5832   Chr21 : 30,758,760
0.491 0.509 0.000
rs12371484 lBF = 19.7008   Chr12 : 111,872,722
0.491 0.509 0.000
rs56890907 lBF = 17.4615   Chr3 : 196,673,831
0.490 0.509 0.000
rs76475900 lBF = 15.2634   Chr16 : 59,672,738
0.490 0.509 0.000
rs115135582 lBF = 12.4642   Chr5 : 119,918,822
0.490 0.510 0.000
rs188135659 lBF = 15.5868   Chr3 : 19,839,062
0.489 0.511 0.000
rs3849590 lBF = 13.7301   Chr4 : 40,837,655
0.489 0.511 0.000
rs1801689 lBF = 8.10652   Chr17 : 64,210,580
0.489 0.511 0.000
rs114355919 lBF = 13.1807   Chr6 : 34,157,315
0.488 0.511 0.000
rs117841971 lBF = 17.8656   Chr10 : 80,699,184
0.488 0.511 0.000
rs28502093 lBF = 12.5607   Chr15 : 78,024,644
0.488 0.511 0.000
rs78652542 lBF = 13.5681   Chr14 : 26,964,012
0.488 0.512 0.000
rs117676517 lBF = 13.7989   Chr11 : 43,925,152
0.487 0.512 0.000
rs11244035 lBF = 23.8973   Chr9 : 136,081,319
0.487 0.513 0.000
rs12898290 lBF = 8.08103   Chr15 : 31,294,343
0.487 0.513 0.000
rs6650640 lBF = 11.0513   Chr18 : 31,748,225
0.487 0.513 0.000
rs79658056 lBF = 13.7273   Chr10 : 74,658,060
0.487 0.513 0.000
rs117576029 lBF = 15.0372   Chr18 : 33,093,123
0.487 0.513 0.000
rs117010525 lBF = 14.7473   Chr17 : 46,605,689
0.487 0.513 0.000
rs78172408 lBF = 11.9224   Chr7 : 47,619,869
0.486 0.513 0.000
rs76848853 lBF = 15.2835   Chr3 : 12,486,981
0.486 0.513 0.000
rs112469508 lBF = 15.1969   Chr7 : 153,176,649
0.486 0.514 0.000
rs36118983 lBF = 13.8019   Chr10 : 91,313,291
0.486 0.514 0.000
rs13141190 lBF = 36.6768   Chr4 : 111,728,614
0.485 0.514 0.000
rs12986171 lBF = 19.4786   Chr19 : 10,773,564
0.485 0.515 0.000
rs79818456 lBF = 12.4174   Chr7 : 33,808,171
0.485 0.515 0.000
rs28668773 lBF = 11.5903   Chr4 : 99,523,890
0.485 0.515 0.000
rs117082835 lBF = 20.3366   Chr22 : 27,493,062
0.485 0.515 0.000
rs75603868 lBF = 15.5379   Chr19 : 8,063,275
0.485 0.515 0.000
rs12433287 lBF = 12.511   Chr14 : 75,697,380
0.485 0.515 0.000
rs79549931 lBF = 22.7675   Chr17 : 66,178,996
0.485 0.515 0.000
rs187986843 lBF = 15.061   Chr12 : 69,080,770
0.484 0.515 0.000
rs649129 lBF = 134.134   Chr9 : 136,154,304
0.484 0.515 0.000
rs117557765 lBF = 20.262   Chr7 : 6,974,872
0.484 0.516 0.000
rs116847944 lBF = 14.8527   Chr17 : 32,238,030
0.484 0.516 0.000
rs62235665 lBF = 13.4781   Chr21 : 41,534,335
0.484 0.516 0.000
rs117508732 lBF = 10.2984   Chr15 : 67,824,170
0.484 0.516 0.000
rs579459 lBF = 134.609   Chr9 : 136,154,168
0.484 0.516 0.000
rs3130564 lBF = 267.188   Chr6 : 31,101,674
0.484 0.516 0.000
rs117069376 lBF = 9.48441   Chr21 : 19,995,322
0.484 0.516 0.000
rs41277101 lBF = 5.09532   Chr9 : 36,337,253
0.484 0.516 0.000
rs200876443 lBF = 17.0144   Chr19 : 50,363,585
0.484 0.516 0.000
rs78216664 lBF = 7.58546   Chr8 : 32,068,317
0.484 0.516 0.000
rs76921037 lBF = 6.40704   Chr11 : 87,489,538
0.484 0.516 0.000
rs651007 lBF = 136.79   Chr9 : 136,153,875
0.484 0.516 0.000
rs116869426 lBF = 8.46932   Chr11 : 47,290,967
0.484 0.516 0.000
rs495828 lBF = 133.813   Chr9 : 136,154,867
0.483 0.516 0.000
rs11044722 lBF = 15.4222   Chr12 : 19,781,710
0.483 0.516 0.000
rs117681218 lBF = 15.1496   Chr19 : 21,045,381
0.483 0.516 0.000
rs114080907 lBF = 15.1857   Chr1 : 21,077,245
0.483 0.517 0.000
rs17094474 lBF = 8.18878   Chr14 : 58,819,463
0.483 0.517 0.000
rs117172322 lBF = 9.83651   Chr8 : 39,522,372
0.483 0.517 0.000
rs295318 lBF = 14.2072   Chr3 : 141,363,176
0.483 0.517 0.000
rs117446263 lBF = 22.5816   Chr6 : 160,847,571
0.483 0.517 0.000
rs112475278 lBF = 12.7647   Chr3 : 103,347,707
0.483 0.517 0.000
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rs10505483 lBF = 15.7887   Chr8 : 128,125,195
0.459 0.541 0.000
rs11088859 lBF = 14.6883   Chr21 : 22,689,344
0.458 0.541 0.000
rs10209766 lBF = 11.0593   Chr2 : 35,161,415
0.458 0.541 0.000
rs2804609 lBF = 22.6812   Chr10 : 113,847,037
0.458 0.542 0.000
rs12682344 lBF = 16.2953   Chr8 : 128,106,784
0.458 0.542 0.000
rs116876575 lBF = 16.1237   Chr22 : 49,899,208
0.458 0.542 0.000
rs34393743 lBF = 12.8628   Chr10 : 90,304,313
0.458 0.542 0.000
rs75444639 lBF = 32.0405   Chr1 : 232,117,041
0.458 0.542 0.000
rs117346609 lBF = 16.6269   Chr7 : 96,852,491
0.458 0.542 0.000
rs72881062 lBF = 15.7439   Chr6 : 56,801,308
0.458 0.542 0.000
rs73030540 lBF = 13.1929   Chr3 : 10,065,254
0.458 0.542 0.000
rs117641416 lBF = 30.5709   Chr22 : 51,123,287
0.458 0.542 0.000
rs17829719 lBF = 15.2172   Chr8 : 1,824,454
0.458 0.542 0.000
rs11743835 lBF = 13.1859   Chr5 : 111,979,658
0.458 0.542 0.000
rs75840590 lBF = 14.2432   Chr7 : 124,290,877
0.458 0.542 0.000
rs113797007 lBF = 25.0423   Chr16 : 12,649,840
0.457 0.542 0.000
rs7830341 lBF = 16.3042   Chr8 : 128,109,930
0.457 0.542 0.000
rs74677747 lBF = 15.6294   Chr10 : 130,448,931
0.457 0.542 0.000
rs74456537 lBF = 16.3397   Chr2 : 158,865,364
0.457 0.542 0.000
rs4252185 lBF = 259.415   Chr6 : 161,123,451
0.457 0.542 0.000
rs118016817 lBF = 16.223   Chr6 : 108,218,801
0.457 0.543 0.000
rs77868089 lBF = 15.3181   Chr13 : 40,396,137
0.457 0.543 0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

 
Variant clusters with highest protective effect

(posterior probability > 0.05)

Cluster X0112
log Bayes Factor = 98.8923
contains 7 variants
0.4262
Cluster X0335
log Bayes Factor = 12.3689
contains 1 variants
0.3403
Cluster X0186
log Bayes Factor = 35.9761
contains 2 variants
0.1776
Cluster X0338
log Bayes Factor = 26.5485
contains 1 variants
0.0650
Variant clusters with highest risk effect

(posterior probability > 0.05)

Cluster X0060
log Bayes Factor = 242.413
contains 5 variants
0.7912
Cluster X0209
log Bayes Factor = 214.798
contains 8 variants
0.6865
Cluster X0321
log Bayes Factor = 162.562
contains 1 variants
0.6054
Cluster X0100
log Bayes Factor = 730.252
contains 26 variants
0.5951
Cluster X0083
log Bayes Factor = 351.917
contains 13 variants
0.5806
Cluster X0123
log Bayes Factor = 382.779
contains 14 variants
0.5785
Cluster X0084
log Bayes Factor = 433.078
contains 21 variants
0.5715
Cluster X0079
log Bayes Factor = 413.803
contains 22 variants
0.5668
Cluster X0326
log Bayes Factor = 112.92
contains 5 variants
0.5520
Cluster X0080
log Bayes Factor = 455.123
contains 21 variants
0.5518
Cluster X0250
log Bayes Factor = 43.399
contains 4 variants
0.5517
Cluster X0064
log Bayes Factor = 166.06
contains 10 variants
0.5488
Cluster X0141
log Bayes Factor = 742.063
contains 30 variants
0.5243
Cluster X0271
log Bayes Factor = 256.743
contains 10 variants
0.5140
Cluster X0146
log Bayes Factor = 686.343
contains 22 variants
0.5140
Cluster X0261
log Bayes Factor = 420.614
contains 20 variants
0.5140
Cluster X0277
log Bayes Factor = 726.213
contains 23 variants
0.5140
Cluster X0086
log Bayes Factor = 131.002
contains 8 variants
0.5140
Cluster X0087
log Bayes Factor = 894.58
contains 26 variants
0.5140
Cluster X0024
log Bayes Factor = 309.44
contains 13 variants
0.5140
Cluster X0057
log Bayes Factor = 439.35
contains 16 variants
0.5140
Cluster X0171
log Bayes Factor = 291.293
contains 14 variants
0.5140
Cluster X0140
log Bayes Factor = 164.536
contains 8 variants
0.5140
Cluster X0188
log Bayes Factor = 222.629
contains 14 variants
0.5140
Cluster X0072
log Bayes Factor = 1189.98
contains 37 variants
0.5140
Cluster X0170
log Bayes Factor = 264.081
contains 11 variants
0.5140
Cluster X0222
log Bayes Factor = 431.582
contains 17 variants
0.5140
Cluster X0094
log Bayes Factor = 562.956
contains 18 variants
0.5139
Cluster X0177
log Bayes Factor = 254.872
contains 10 variants
0.5139
Cluster X0122
log Bayes Factor = 219.114
contains 9 variants
0.5139
Cluster X0044
log Bayes Factor = 1165.44
contains 34 variants
0.5139
Cluster X0032
log Bayes Factor = 255.737
contains 12 variants
0.5139
Cluster X0091
log Bayes Factor = 303.64
contains 12 variants
0.5139
Cluster X0049
log Bayes Factor = 597.061
contains 18 variants
0.5138
Cluster X0075
log Bayes Factor = 431.344
contains 16 variants
0.5138
Cluster X0280
log Bayes Factor = 86.0876
contains 1 variants
0.5138
Cluster X0085
log Bayes Factor = 138.902
contains 6 variants
0.5138
Cluster X0257
log Bayes Factor = 281.184
contains 10 variants
0.5138
Cluster X0232
log Bayes Factor = 695.273
contains 23 variants
0.5138
Cluster X0073
log Bayes Factor = 785.614
contains 25 variants
0.5137
Cluster X0045
log Bayes Factor = 446.264
contains 16 variants
0.5137
Cluster X0055
log Bayes Factor = 274.911
contains 10 variants
0.5137
Cluster X0043
log Bayes Factor = 517.108
contains 20 variants
0.5137
Cluster X0020
log Bayes Factor = 557.721
contains 18 variants
0.5136
Cluster X0093
log Bayes Factor = 289.878
contains 10 variants
0.5136
Cluster X0109
log Bayes Factor = 257.685
contains 11 variants
0.5135
Cluster X0224
log Bayes Factor = 278.692
contains 11 variants
0.5135
Cluster X0197
log Bayes Factor = 158.582
contains 8 variants
0.5134
Cluster X0051
log Bayes Factor = 376.793
contains 14 variants
0.5134
Cluster X0145
log Bayes Factor = 274.587
contains 11 variants
0.5134
Cluster X0258
log Bayes Factor = 104.851
contains 6 variants
0.5133
Cluster X0205
log Bayes Factor = 674.183
contains 18 variants
0.5132
Cluster X0098
log Bayes Factor = 246.226
contains 8 variants
0.5131
Cluster X0227
log Bayes Factor = 249.287
contains 11 variants
0.5131
Cluster X0007
log Bayes Factor = 107.567
contains 7 variants
0.5130
Cluster X0150
log Bayes Factor = 861.091
contains 26 variants
0.5128
Cluster X0166
log Bayes Factor = 230.746
contains 8 variants
0.5128
Cluster X0039
log Bayes Factor = 463.231
contains 17 variants
0.5127
Cluster X0246
log Bayes Factor = 121.08
contains 5 variants
0.5127
Cluster X0124
log Bayes Factor = 336.468
contains 13 variants
0.5126
Cluster X0192
log Bayes Factor = 402.511
contains 14 variants
0.5126
Cluster X0153
log Bayes Factor = 328.394
contains 11 variants
0.5126
Cluster X0203
log Bayes Factor = 363.522
contains 11 variants
0.5126
Cluster X0042
log Bayes Factor = 307.243
contains 12 variants
0.5125
Cluster X0164
log Bayes Factor = 463.793
contains 16 variants
0.5124
Cluster X0174
log Bayes Factor = 214.209
contains 8 variants
0.5123
Cluster X0003
log Bayes Factor = 195.6
contains 8 variants
0.5122
Cluster X0028
log Bayes Factor = 120.445
contains 7 variants
0.5119
Cluster X0059
log Bayes Factor = 922.497
contains 26 variants
0.5119
Cluster X0161
log Bayes Factor = 609.219
contains 20 variants
0.5115
Cluster X0220
log Bayes Factor = 142.284
contains 7 variants
0.5112
Cluster X0143
log Bayes Factor = 179.808
contains 8 variants
0.5109
Cluster X0249
log Bayes Factor = 244.457
contains 11 variants
0.5102
Cluster X0284
log Bayes Factor = 192.532
contains 9 variants
0.5100
Cluster X0155
log Bayes Factor = 348.568
contains 12 variants
0.5096
Cluster X0078
log Bayes Factor = 203.49
contains 11 variants
0.5095
Cluster X0240
log Bayes Factor = 104.862
contains 6 variants
0.5088
Cluster X0026
log Bayes Factor = 232.119
contains 9 variants
0.5088
Cluster X0077
log Bayes Factor = 571.533
contains 17 variants
0.5086
Cluster X0053
log Bayes Factor = 218.825
contains 12 variants
0.5081
Cluster X0182
log Bayes Factor = 91.4459
contains 4 variants
0.5080
Cluster X0005
log Bayes Factor = 282.915
contains 11 variants
0.5070
Cluster X0139
log Bayes Factor = 304.555
contains 10 variants
0.5064
Cluster X0069
log Bayes Factor = 519.392
contains 20 variants
0.5055
Cluster X0181
log Bayes Factor = 141.396
contains 6 variants
0.5054
Cluster X0201
log Bayes Factor = 368.049
contains 13 variants
0.5054
Cluster X0074
log Bayes Factor = 353.38
contains 15 variants
0.5054
Cluster X0106
log Bayes Factor = 980.916
contains 30 variants
0.5052
Cluster X0129
log Bayes Factor = 195.809
contains 7 variants
0.5052
Cluster X0253
log Bayes Factor = 331.491
contains 13 variants
0.5042
Cluster X0221
log Bayes Factor = 149.378
contains 10 variants
0.5040
Cluster X0088
log Bayes Factor = 243.609
contains 9 variants
0.5035
Cluster X0256
log Bayes Factor = 211.588
contains 9 variants
0.5032
Cluster X0111
log Bayes Factor = 403.183
contains 18 variants
0.5032
Cluster X0052
log Bayes Factor = 654.387
contains 25 variants
0.5028
Cluster X0165
log Bayes Factor = 303.727
contains 12 variants
0.5018
Cluster X0210
log Bayes Factor = 426.159
contains 17 variants
0.5003
Cluster X0290
log Bayes Factor = 333.908
contains 13 variants
0.4982
Cluster X0110
log Bayes Factor = 721.325
contains 13 variants
0.4963
Cluster X0243
log Bayes Factor = 104.974
contains 6 variants
0.4958
Cluster X0037
log Bayes Factor = 171.712
contains 6 variants
0.4950
Cluster X0237
log Bayes Factor = 123.902
contains 6 variants
0.4947
Cluster X0082
log Bayes Factor = 496.905
contains 17 variants
0.4945
Cluster X0189
log Bayes Factor = 149.681
contains 5 variants
0.4942
Cluster X0102
log Bayes Factor = 99.5678
contains 5 variants
0.4939
Cluster X0142
log Bayes Factor = 295.63
contains 12 variants
0.4937
Cluster X0180
log Bayes Factor = 410.88
contains 15 variants
0.4932
Cluster X0176
log Bayes Factor = 407.797
contains 14 variants
0.4930
Cluster X0156
log Bayes Factor = 226.954
contains 9 variants
0.4908
Cluster X0012
log Bayes Factor = 112.432
contains 5 variants
0.4900
Cluster X0212
log Bayes Factor = 300.777
contains 10 variants
0.4898
Cluster X0040
log Bayes Factor = 542.747
contains 16 variants
0.4891
Cluster X0226
log Bayes Factor = 145.726
contains 8 variants
0.4890
Cluster X0021
log Bayes Factor = 338.631
contains 13 variants
0.4883
Cluster X0167
log Bayes Factor = 136.48
contains 6 variants
0.4878
Cluster X0248
log Bayes Factor = 254.854
contains 10 variants
0.4868
Cluster X0208
log Bayes Factor = 40.6733
contains 2 variants
0.4848
Cluster X0071
log Bayes Factor = 131.269
contains 6 variants
0.4844
Cluster X0214
log Bayes Factor = 186.582
contains 8 variants
0.4840
Cluster X0019
log Bayes Factor = 372.36
contains 16 variants
0.4838
Cluster X0231
log Bayes Factor = 82.3185
contains 5 variants
0.4829
Cluster X0293
log Bayes Factor = 169.051
contains 7 variants
0.4822
Cluster X0041
log Bayes Factor = 306.192
contains 14 variants
0.4773
Cluster X0275
log Bayes Factor = 219.726
contains 10 variants
0.4763
Cluster X0238
log Bayes Factor = 97.9307
contains 4 variants
0.4761
Cluster X0046
log Bayes Factor = 387.972
contains 16 variants
0.4759
Cluster X0081
log Bayes Factor = 278.568
contains 10 variants
0.4751
Cluster X0178
log Bayes Factor = 225.6
contains 9 variants
0.4750
Cluster X0070
log Bayes Factor = 421.182
contains 15 variants
0.4748
Cluster X0274
log Bayes Factor = 454.783
contains 18 variants
0.4744
Cluster X0119
log Bayes Factor = 114.358
contains 6 variants
0.4712
Cluster X0089
log Bayes Factor = 308.747
contains 13 variants
0.4710
Cluster X0213
log Bayes Factor = 405.918
contains 15 variants
0.4681
Cluster X0133
log Bayes Factor = 224.204
contains 11 variants
0.4668
Cluster X0327
log Bayes Factor = 118.248
contains 3 variants
0.4663
Cluster X0058
log Bayes Factor = 183.199
contains 8 variants
0.4654
Cluster X0194
log Bayes Factor = 189.9
contains 5 variants
0.4644
Cluster X0297
log Bayes Factor = 63.8292
contains 4 variants
0.4613
Cluster X0218
log Bayes Factor = 425.579
contains 18 variants
0.4503
Cluster X0157
log Bayes Factor = 172.957
contains 8 variants
0.4494
Cluster X0029
log Bayes Factor = 709.102
contains 23 variants
0.4492
Cluster X0134
log Bayes Factor = 151.731
contains 8 variants
0.4322
Cluster X0050
log Bayes Factor = 397.79
contains 16 variants
0.4316
Cluster X0038
log Bayes Factor = 31.1234
contains 2 variants
0.4238
Cluster X0337
log Bayes Factor = 84.9395
contains 2 variants
0.4226
Cluster X0339
log Bayes Factor = 56.078
contains 2 variants
0.4225
Cluster X0268
log Bayes Factor = 213.591
contains 8 variants
0.4220
Cluster X0118
log Bayes Factor = 91.1908
contains 5 variants
0.4187
Cluster X0033
log Bayes Factor = 379.444
contains 13 variants
0.4071
Cluster X0163
log Bayes Factor = 122.554
contains 6 variants
0.4071
Cluster X0014
log Bayes Factor = 131.677
contains 6 variants
0.4068
Cluster X0047
log Bayes Factor = 378.621
contains 14 variants
0.4045
Cluster X0294
log Bayes Factor = 25.2869
contains 2 variants
0.4045
Cluster X0076
log Bayes Factor = 310.928
contains 15 variants
0.4027
Cluster X0001
log Bayes Factor = 167.541
contains 7 variants
0.3962
Cluster X0137
log Bayes Factor = 120.748
contains 4 variants
0.3932
Cluster X0229
log Bayes Factor = 347.165
contains 13 variants
0.3829
Cluster X0054
log Bayes Factor = 197.338
contains 9 variants
0.3796
Cluster X0015
log Bayes Factor = 356.23
contains 15 variants
0.3787
Cluster X0067
log Bayes Factor = 179.381
contains 8 variants
0.3695
Cluster X0132
log Bayes Factor = 267.393
contains 11 variants
0.3673
Cluster X0126
log Bayes Factor = 384.432
contains 15 variants
0.3657
Cluster X0259
log Bayes Factor = 246.237
contains 11 variants
0.3603
Cluster X0107
log Bayes Factor = 151.016
contains 1 variants
0.3581
Cluster X0191
log Bayes Factor = 163.555
contains 8 variants
0.3561
Cluster X0330
log Bayes Factor = 183.455
contains 2 variants
0.3492
Cluster X0287
log Bayes Factor = 33.3095
contains 4 variants
0.3485
Cluster X0263
log Bayes Factor = 240.36
contains 13 variants
0.3428
Cluster X0264
log Bayes Factor = 205.833
contains 10 variants
0.3374
Cluster X0307
log Bayes Factor = 826.86
contains 2 variants
0.3344
Cluster X0148
log Bayes Factor = 315.237
contains 11 variants
0.3254
Cluster X0204
log Bayes Factor = 169.796
contains 8 variants
0.3165
Cluster X0030
log Bayes Factor = 216.364
contains 9 variants
0.3157
Cluster X0184
log Bayes Factor = 188.416
contains 8 variants
0.3133
Cluster X0152
log Bayes Factor = 331.156
contains 10 variants
0.3126
Cluster X0063
log Bayes Factor = 107.557
contains 5 variants
0.3043
Cluster X0018
log Bayes Factor = 430.611
contains 18 variants
0.3025
Cluster X0236
log Bayes Factor = 83.9265
contains 3 variants
0.3012
Cluster X0154
log Bayes Factor = 282.084
contains 12 variants
0.2986
Cluster X0048
log Bayes Factor = 358.819
contains 19 variants
0.2834
Cluster X0320
log Bayes Factor = 110.964
contains 6 variants
0.2829
Cluster X0159
log Bayes Factor = 152.327
contains 7 variants
0.2788
Cluster X0283
log Bayes Factor = 162.98
contains 9 variants
0.2696
Cluster X0138
log Bayes Factor = 43.7891
contains 4 variants
0.2638
Cluster X0162
log Bayes Factor = 144.479
contains 9 variants
0.2619
Cluster X0068
log Bayes Factor = 127.774
contains 6 variants
0.2608
Cluster X0322
log Bayes Factor = 70.0115
contains 3 variants
0.2545
Cluster X0117
log Bayes Factor = 453.246
contains 21 variants
0.2483
Cluster X0276
log Bayes Factor = 187.108
contains 9 variants
0.2472
Cluster X0095
log Bayes Factor = 179.348
contains 8 variants
0.2339
Cluster X0120
log Bayes Factor = 79.6695
contains 4 variants
0.2176
Cluster X0061
log Bayes Factor = 293.105
contains 15 variants
0.2175
Cluster X0332
log Bayes Factor = 65.2374
contains 3 variants
0.2126
Cluster X0324
log Bayes Factor = 32.1341
contains 1 variants
0.1990
Cluster X0121
log Bayes Factor = 131.08
contains 9 variants
0.1933
Cluster X0131
log Bayes Factor = 143.942
contains 8 variants
0.1913
Cluster X0185
log Bayes Factor = 84.7127
contains 6 variants
0.1715
Cluster X0013
log Bayes Factor = 548.265
contains 23 variants
0.1488
Cluster X0169
log Bayes Factor = 331.98
contains 16 variants
0.1050
Cluster X0114
log Bayes Factor = 510.917
contains 25 variants
0.0703
Cluster X0262
log Bayes Factor = 269.713
contains 9 variants
0.0532
 
 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

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