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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7778881
log Bayes Factor = 12.4659
Chromosome 7   position 66,460,011  (GRCh37) Explore rs7778881 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
C79 Secondary malignant neoplasm of other sites
0.998 0.002 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.997 0.003 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.993 0.007 0.000
A30-A49 Other bacterial diseases
0.991 0.009 0.000
D60-D64 Aplastic and other anaemias
0.981 0.019 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.980 0.020 0.000
C78.0 Secondary malignant neoplasm of lung
0.975 0.025 0.000
B35-B49 Mycoses
0.974 0.026 0.000
C77.1 Intrathoracic lymph nodes
0.970 0.030 0.000
M20-M25 Other joint disorders
0.969 0.031 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.966 0.034 0.000
B37 Candidiasis
0.954 0.046 0.000
C78.2 Secondary malignant neoplasm of pleura
0.954 0.046 0.000
C78.7 Secondary malignant neoplasm of liver
0.948 0.052 0.000
D61 Other aplastic anaemias
0.944 0.056 0.000
M23 Internal derangement of knee
0.937 0.063 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.936 0.064 0.000
C77.0 Lymph nodes of head, face and neck
0.932 0.068 0.000
Z51 Other medical care
0.929 0.071 0.000
Chapter IX Diseases of the circulatory system
0.928 0.072 0.000
C51-C58 Malignant neoplasms of female genital organs
0.925 0.075 0.000
I05-I09 Chronic rheumatic heart diseases
0.922 0.078 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.921 0.079 0.000
M45-M49 Spondylopathies
0.920 0.080 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.919 0.081 0.000
A41 Other septicaemia
0.918 0.082 0.000
D61.9 Aplastic anaemia, unspecified
0.917 0.083 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.916 0.084 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.916 0.084 0.000
I08 Multiple valve diseases
0.916 0.084 0.000
C77.4 Inguinal and lower limb lymph nodes
0.914 0.086 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.911 0.089 0.000
Chapter XXI Factors influencing health status and contact with health services
0.910 0.090 0.000
A49 Bacterial infection of unspecified site
0.909 0.091 0.000
Z51.5 Palliative care
0.907 0.093 0.000
R50-R69 General symptoms and signs
0.901 0.099 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.900 0.100 0.000
C80 Malignant neoplasm without specification of site
0.898 0.102 0.000
Chapter VI Diseases of the nervous system
0.895 0.105 0.000
M48 Other spondylopathies
0.894 0.106 0.000
R53 Malaise and fatigue
0.893 0.107 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.892 0.108 0.000
B37.8 Candidiasis of other sites
0.891 0.109 0.000
C77.8 Lymph nodes of multiple regions
0.881 0.119 0.000
A40 Streptococcal septicaemia
0.880 0.120 0.000
R52 Pain, not elsewhere classified
0.879 0.121 0.000
M48.0 Spinal stenosis
0.877 0.123 0.000
D50-D53 Nutritional anaemias
0.875 0.124 0.000
D64 Other anaemias
0.875 0.125 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.871 0.129 0.000
M48.06 Spinal stenosis (Lumbar region)
0.866 0.134 0.000
C56 Malignant neoplasm of ovary
0.865 0.135 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.865 0.135 0.000
C50-C50 Malignant neoplasm of breast
0.864 0.136 0.000
Z51.1 Chemotherapy session for neoplasm
0.857 0.143 0.000
G90-G99 Other disorders of the nervous system
0.856 0.144 0.000
Z51.0 Radiotherapy session
0.854 0.146 0.000
G40-G47 Episodic and paroxysmal disorders
0.852 0.148 0.000
I08.0 Disorders of both mitral and aortic valves
0.850 0.150 0.000
Z43 Attention to artificial openings
0.842 0.158 0.000
B37.9 Candidiasis, unspecified
0.839 0.161 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.838 0.162 0.000
M22 Disorders of patella
0.836 0.164 0.000
V40-V49 Car occupant injured in transport accident
0.834 0.165 0.000
M24 Other specific joint derangements
0.834 0.166 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.831 0.169 0.000
B65-B83 Helminthiases
0.831 0.169 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.830 0.170 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.830 0.170 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.827 0.173 0.000
X60-X84 Intentional self-harm
0.823 0.177 0.000
D80-D89 Certain disorders involving the immune mechanism
0.821 0.179 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.820 0.180 0.000
M86-M90 Other osteopathies
0.817 0.183 0.000
W20-W49 Exposure to inanimate mechanical forces
0.816 0.184 0.000
Z46 Fitting and adjustment of other devices
0.815 0.185 0.000
A49.9 Bacterial infection, unspecified
0.812 0.188 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.811 0.189 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.811 0.189 0.000
M21 Other acquired deformities of limbs
0.809 0.191 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.808 0.192 0.000
C79.2 Secondary malignant neoplasm of skin
0.808 0.192 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.807 0.193 0.000
Chapter XXII Codes for special purposes
0.804 0.196 0.000
R52.1 Chronic intractable pain
0.801 0.199 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.801 0.199 0.000
D64.9 Anaemia, unspecified
0.799 0.201 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.798 0.202 0.000
M30 Polyarteritis nodosa and related conditions
0.796 0.204 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.796 0.204 0.000
Z48 Other surgical follow-up care
0.794 0.206 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.794 0.206 0.000
R59 Enlarged lymph nodes
0.794 0.206 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.794 0.206 0.000
Y43 Primarily systemic agents
0.793 0.207 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.793 0.207 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.791 0.209 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.789 0.211 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.789 0.211 0.000
R52.0 Acute pain
0.784 0.216 0.000
C77.2 Intra-abdominal lymph nodes
0.784 0.216 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.784 0.216 0.000
Z43.3 Attention to colostomy
0.783 0.217 0.000
A46 Erysipelas
0.783 0.217 0.000
B37.0 Candidal stomatitis
0.783 0.217 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.781 0.219 0.000
Z42 Follow-up care involving plastic surgery
0.780 0.220 0.000
O60-O75 Complications of labour and delivery
0.780 0.220 0.000
M23.4 Loose body in knee
0.780 0.220 0.000
A40.8 Other streptococcal septicaemia
0.779 0.221 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.778 0.222 0.000
B37.4 Candidiasis of other urogenital sites
0.777 0.223 0.000
I05 Rheumatic mitral valve diseases
0.776 0.224 0.000
D51 Vitamin B12 deficiency anaemia
0.776 0.224 0.000
B50-B64 Protozoal diseases
0.775 0.225 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.774 0.226 0.000
D70 Agranulocytosis
0.774 0.226 0.000
W00-W19 Falls
0.774 0.226 0.000
A49.8 Other bacterial infections of unspecified site
0.773 0.227 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.772 0.228 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.771 0.229 0.000
R60 Oedema, not elsewhere classified
0.769 0.231 0.000
C50 Malignant neoplasm of breast
0.767 0.233 0.000
M05-M14 Inflammatory polyarthropathies
0.767 0.233 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.767 0.233 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.766 0.234 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.763 0.237 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.761 0.239 0.000
M23.0 Cystic meniscus
0.761 0.239 0.000
R30-R39 Symptoms and signs involving the urinary system
0.758 0.242 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.757 0.242 0.000
D55-D59 Haemolytic anaemias
0.756 0.244 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.755 0.244 0.000
M33 Dermatopolymyositis
0.754 0.245 0.000
Y65 Other misadventures during surgical and medical care
0.754 0.246 0.000
G40 Epilepsy
0.754 0.246 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.753 0.247 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.752 0.248 0.000
C60-C63 Malignant neoplasms of male genital organs
0.750 0.250 0.000
B49 Unspecified mycosis
0.749 0.251 0.000
R47-R49 Symptoms and signs involving speech and voice
0.748 0.252 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.748 0.252 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.746 0.254 0.000
M24.1 Other articular cartilage disorders
0.744 0.256 0.000
G95 Other diseases of spinal cord
0.743 0.257 0.000
C50.1 Central portion of breast
0.741 0.259 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.740 0.260 0.000
Y60.0 During surgical operation
0.739 0.261 0.000
M35 Other systemic involvement of connective tissue
0.738 0.262 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.736 0.264 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.734 0.266 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.733 0.267 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.732 0.267 0.000
R52.2 Other chronic pain
0.732 0.268 0.000
X20-X29 Contact with venomous animals and plants
0.731 0.269 0.000
W22 Striking against or struck by other objects
0.727 0.273 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.724 0.276 0.000
V10-V19 Pedal cyclist injured in transport accident
0.724 0.276 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.723 0.276 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.723 0.277 0.000
V20-V29 Motorcycle rider injured in transport accident
0.723 0.277 0.000
C80.9 Malignant neoplasm, unspecified
0.721 0.279 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.721 0.279 0.000
G43 Migraine
0.719 0.281 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.719 0.281 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.719 0.281 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.719 0.281 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.717 0.283 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C34 Malignant neoplasm of bronchus and lung
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.283 0.000
A75-A79 Rickettsioses
0.716 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.283 0.000
A65-A69 Other spirochaetal diseases
0.716 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.283 0.000
A15-A19 Tuberculosis
0.716 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.284 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.715 0.285 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.715 0.285 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.712 0.288 0.000
G90 Disorders of autonomic nervous system
0.711 0.289 0.000
B80 Enterobiasis
0.710 0.290 0.000
A48 Other bacterial diseases, not elsewhere classified
0.710 0.290 0.000
A44 Bartonellosis
0.710 0.290 0.000
A43 Nocardiosis
0.710 0.290 0.000
A42 Actinomycosis
0.710 0.290 0.000
A39 Meningococcal infection
0.710 0.290 0.000
A37 Whooping cough
0.710 0.290 0.000
A36 Diphtheria
0.710 0.290 0.000
A32 Listeriosis
0.710 0.290 0.000
A31 Infection due to other mycobacteria
0.710 0.290 0.000
A30 Leprosy [Hansen's disease]
0.710 0.290 0.000
A38 Scarlet fever
0.710 0.290 0.000
A35 Other tetanus
0.710 0.290 0.000
A34 Obstetrical tetanus
0.710 0.290 0.000
A33 Tetanus neonatorum
0.710 0.290 0.000
B99-B99 Other infectious diseases
0.708 0.292 0.000
Z40 Prophylactic surgery
0.707 0.293 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.703 0.296 0.000
M60-M63 Disorders of muscles
0.703 0.297 0.000
G47 Sleep disorders
0.701 0.299 0.000
D73 Diseases of spleen
0.700 0.300 0.000
M40-M43 Deforming dorsopathies
0.699 0.301 0.000
B48 Other mycoses, not elsewhere classified
0.698 0.302 0.000
B47 Mycetoma
0.698 0.302 0.000
B46 Zygomycosis
0.698 0.302 0.000
B45 Cryptococcosis
0.698 0.302 0.000
B43 Chromomycosis and phaeomycotic abscess
0.698 0.302 0.000
B42 Sporotrichosis
0.698 0.302 0.000
B41 Paracoccidioidomycosis
0.698 0.302 0.000
B40 Blastomycosis
0.698 0.302 0.000
B39 Histoplasmosis
0.698 0.302 0.000
B38 Coccidioidomycosis
0.698 0.302 0.000
B36 Other superficial mycoses
0.698 0.302 0.000
C53 Malignant neoplasm of cervix uteri
0.697 0.303 0.000
A80-A89 Viral infections of the central nervous system
0.697 0.303 0.000
M31 Other necrotising vasculopathies
0.696 0.304 0.000
L20-L30 Dermatitis and eczema
0.696 0.304 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.695 0.304 0.000
R49 Voice disturbances
0.695 0.305 0.000
M48.09 Spinal stenosis (Site unspecified)
0.695 0.305 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.695 0.305 0.000
M32 Systemic lupus erythematosus
0.695 0.305 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.695 0.305 0.000
R68 Other general symptoms and signs
0.695 0.305 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.695 0.305 0.000
M00-M03 Infectious arthropathies
0.694 0.305 0.000
R32 Unspecified urinary incontinence
0.694 0.306 0.000
B15-B19 Viral hepatitis
0.694 0.306 0.000
R82 Other abnormal findings in urine
0.694 0.306 0.000
Z51.8 Other specified medical care
0.693 0.306 0.000
O62 Abnormalities of forces of labour
0.693 0.307 0.000
B25-B34 Other viral diseases
0.693 0.307 0.000
M22.4 Chondromalacia patellae
0.691 0.308 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.691 0.309 0.000
R79 Other abnormal findings of blood chemistry
0.691 0.309 0.000
Z48.0 Attention to surgical dressings and sutures
0.689 0.311 0.000
R33 Retention of urine
0.689 0.311 0.000
C79.6 Secondary malignant neoplasm of ovary
0.688 0.312 0.000
R59.0 Localised enlarged lymph nodes
0.687 0.313 0.000
B35 Dermatophytosis
0.686 0.314 0.000
A40.3 Septicaemia due to Streptococcus pneumoniae
0.685 0.315 0.000
B37.7 Candidal septicaemia
0.684 0.316 0.000
B37.6 Candidal endocarditis
0.684 0.316 0.000
B37.5 Candidal meningitis
0.684 0.316 0.000
B37.2 Candidiasis of skin and nail
0.684 0.316 0.000
B37.1 Pulmonary candidiasis
0.684 0.316 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.684 0.316 0.000
M90 Osteopathies in diseases classified elsewhere
0.684 0.316 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.684 0.316 0.000
X78 Intentional self-harm by sharp object
0.682 0.318 0.000
C45 Mesothelioma
0.682 0.318 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.681 0.319 0.000
R59.1 Generalised enlarged lymph nodes
0.680 0.320 0.000
Y95 Nosocomial condition
0.679 0.321 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.679 0.321 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.679 0.321 0.000
I10-I15 Hypertensive diseases
0.679 0.321 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.677 0.323 0.000
D61.8 Other specified aplastic anaemias
0.677 0.323 0.000
D61.3 Idiopathic aplastic anaemia
0.677 0.323 0.000
D61.2 Aplastic anaemia due to other external agents
0.677 0.323 0.000
D61.1 Drug-induced aplastic anaemia
0.677 0.323 0.000
D61.0 Constitutional aplastic anaemia
0.677 0.323 0.000
M65-M68 Disorders of synovium and tendon
0.676 0.324 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.675 0.325 0.000
M34 Systemic sclerosis
0.675 0.325 0.000
G93 Other disorders of brain
0.674 0.326 0.000
R58 Haemorrhage, not elsewhere classified
0.672 0.328 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.672 0.328 0.000
Z52 Donors of organs and tissues
0.672 0.328 0.000
M23.9 Internal derangement of knee, unspecified
0.672 0.328 0.000
M23.1 Discoid meniscus (congenital)
0.672 0.328 0.000
C64-C68 Malignant neoplasms of urinary tract
0.672 0.328 0.000
Y59 Other and unspecified vaccines and biological substances
0.671 0.329 0.000
Y58 Bacterial vaccines
0.671 0.329 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.671 0.329 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.671 0.329 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.671 0.329 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.671 0.329 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.671 0.329 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.671 0.329 0.000
Y48 Anaesthetics and therapeutic gases
0.671 0.329 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.671 0.329 0.000
A49.1 Streptococcal infection, unspecified
0.671 0.329 0.000
Y42.7 Androgens and anabolic congeners
0.670 0.330 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.670 0.330 0.000
M06 Other rheumatoid arthritis
0.668 0.332 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.668 0.332 0.000
B44 Aspergillosis
0.667 0.333 0.000
M23.49 Loose body in knee-Unspec lig/men
0.667 0.333 0.000
Z51.6 Desensitisation to allergens
0.666 0.334 0.000
V80-V89 Other land transport accidents
0.666 0.334 0.000
I00-I02 Acute rheumatic fever
0.665 0.335 0.000
Y57 Other and unspecified drugs and medicaments
0.665 0.335 0.000
W22.9 Unspecified place
0.664 0.336 0.000
Y44 Agents primarily affecting blood constituents
0.664 0.336 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.663 0.336 0.000
C51 Malignant neoplasm of vulva
0.663 0.336 0.000
C58 Malignant neoplasm of placenta
0.663 0.336 0.000
C52 Malignant neoplasm of vagina
0.663 0.336 0.000
D86 Sarcoidosis
0.663 0.337 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.663 0.337 0.000
R71 Abnormality of red blood cells
0.663 0.337 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.662 0.338 0.000
M87 Osteonecrosis
0.661 0.339 0.000
I09 Other rheumatic heart diseases
0.661 0.339 0.000
I06 Rheumatic aortic valve diseases
0.661 0.339 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.661 0.339 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.660 0.340 0.000
M49 Spondylopathies in diseases classified elsewhere
0.660 0.340 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.659 0.341 0.000
Z44 Fitting and adjustment of external prosthetic device
0.659 0.341 0.000
M22.8 Other disorders of patella
0.659 0.341 0.000
A41.4 Septicaemia due to anaerobes
0.658 0.342 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.658 0.342 0.000
M25 Other joint disorders, not elsewhere classified
0.657 0.342 0.000
R49.0 Dysphonia
0.657 0.343 0.000
Z43.5 Attention to cyctostomy
0.657 0.343 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.657 0.343 0.000
M21.6 Other acquired deformities of ankle and foot
0.657 0.343 0.000
R60.0 Localised oedema
0.657 0.343 0.000
I08.9 Multiple valve disease, unspecified
0.657 0.343 0.000
Y43.4 Immunosuppressive agents
0.656 0.344 0.000
M21.2 Flexion deformity
0.656 0.344 0.000
D63.0 Anaemia in neoplastic disease
0.655 0.344 0.000
R52.9 Pain, unspecified
0.655 0.344 0.000
Y64 Contaminated medical or biological substances
0.653 0.347 0.000
Y63 Failure in dosage during surgical and medical care
0.653 0.347 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.653 0.347 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.653 0.347 0.000
Y69 Unspecified misadventure during surgical and medical care
0.653 0.347 0.000
Y66 Nonadministration of surgical and medical care
0.653 0.347 0.000
M91-M94 Chondropathies
0.653 0.347 0.000
I30-I52 Other forms of heart disease
0.653 0.347 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.653 0.347 0.000
A49.3 Mycoplasma infection, unspecified
0.651 0.348 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.651 0.348 0.000
M23.5 Chronic instability of knee
0.651 0.349 0.000
Q50-Q56 Congenital malformations of genital organs
0.650 0.350 0.000
D62 Acute posthaemorrhagic anaemia
0.650 0.350 0.000
C02.9 Tongue, unspecified
0.649 0.351 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.649 0.351 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.648 0.351 0.000
G43.9 Migraine, unspecified
0.648 0.352 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.648 0.352 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.648 0.352 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.647 0.353 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.647 0.353 0.000
R79.0 Abnormal level of blood mineral
0.647 0.353 0.000
I71 Aortic aneurysm and dissection
0.646 0.354 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.646 0.354 0.000
R62 Lack of expected normal physiological development
0.646 0.354 0.000
R64 Cachexia
0.646 0.354 0.000
D50 Iron deficiency anaemia
0.646 0.354 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.644 0.356 0.000
Z54 Convalescence
0.644 0.356 0.000
L30 Other dermatitis
0.644 0.356 0.000
Z43.8 Attention to other artificial openings
0.644 0.356 0.000
D84 Other immunodeficiencies
0.643 0.357 0.000
D52 Folate deficiency anaemia
0.643 0.357 0.000
M45 Ankylosing spondylitis
0.642 0.358 0.000
Z51.9 Medical care, unspecified
0.641 0.358 0.000
M48.9 Spondylopathy, unspecified
0.641 0.359 0.000
M48.8 Other specified spondylopathies
0.641 0.359 0.000
M48.4 Fatigue fracture of vertebra
0.641 0.359 0.000
M48.3 Traumatic spondylopathy
0.641 0.359 0.000
M48.2 Kissing spine
0.641 0.359 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.641 0.359 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.641 0.359 0.000
I08.8 Other multiple valve diseases
0.640 0.360 0.000
A00-A09 Intestinal infectious diseases
0.640 0.360 0.000
R57 Shock, not elsewhere classified
0.639 0.361 0.000
Y40 Systemic antibiotics
0.638 0.362 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.638 0.362 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.638 0.362 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.637 0.363 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.637 0.363 0.000
S90-S99 Injuries to the ankle and foot
0.636 0.364 0.000
S50-S59 Injuries to the elbow and forearm
0.636 0.364 0.000
V49.9 Car occupant [any] injured in unspecified traffic accident
0.636 0.364 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.635 0.365 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.635 0.365 0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.635 0.365 0.000
Z43.2 Attention to ileostomy
0.633 0.367 0.000
Z48.8 Other specified surgical follow-up care
0.632 0.368 0.000
O62.2 Other uterine inertia
0.632 0.368 0.000
I07 Rheumatic tricuspid valve diseases
0.631 0.369 0.000
A40.9 Streptococcal septicaemia, unspecified
0.631 0.369 0.000
A40.2 Septicaemia due to streptococcus, group D
0.631 0.369 0.000
A40.1 Septicaemia due to streptococcus, group B
0.631 0.369 0.000
A40.0 Septicaemia due to streptococcus, group A
0.631 0.369 0.000
M21.0 Valgus deformity, not elsewhere classified
0.631 0.369 0.000
I34 Nonrheumatic mitral valve disorders
0.630 0.370 0.000
C77.9 Lymph node, unspecified
0.630 0.370 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.629 0.371 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.629 0.371 0.000
M48.04 Spinal stenosis (Thoracic region)
0.629 0.371 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.629 0.371 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.629 0.371 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.628 0.372 0.000
C50.2 Upper-inner quadrant of breast
0.628 0.372 0.000
D53 Other nutritional anaemias
0.628 0.372 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.627 0.372 0.000
D64.8 Other specified anaemias
0.627 0.373 0.000
D64.4 Congenital dyserythropoietic anaemia
0.627 0.373 0.000
D64.3 Other sideroblastic anaemias
0.627 0.373 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.627 0.373 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.627 0.373 0.000
D64.0 Hereditary sideroblastic anaemia
0.627 0.373 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.627 0.373 0.000
M22.2 Patellofemoral disorders
0.627 0.373 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.626 0.374 0.000
R73 Elevated blood glucose level
0.626 0.374 0.000
I12 Hypertensive renal disease
0.626 0.374 0.000
M05 Seropositive rheumatoid arthritis
0.625 0.375 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.625 0.375 0.000
D74 Methaemoglobinaemia
0.625 0.375 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.625 0.375 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.625 0.375 0.000
Z46.6 Fitting and adjustment of urinary device
0.624 0.376 0.000
S10-S19 Injuries to the neck
0.623 0.377 0.000
T66-T78 Other and unspecified effects of external causes
0.623 0.377 0.000
Z46.8 Fitting and adjustment of other specified devices
0.623 0.377 0.000
I05.9 Mitral valve disease, unspecified
0.622 0.378 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.621 0.379 0.000
B37.3 Candidiasis of vulva and vagina
0.621 0.379 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.621 0.379 0.000
R74 Abnormal serum enzyme levels
0.620 0.380 0.000
C73 Malignant neoplasm of thyroid gland
0.619 0.381 0.000
G41 Status epilepticus
0.618 0.382 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.618 0.382 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.617 0.383 0.000
Y45.0 Opioids and related analgesics
0.617 0.383 0.000
M48.02 Spinal stenosis (Cervical region)
0.617 0.383 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.615 0.385 0.000
B59 Pneumocystosis
0.614 0.386 0.000
C07 Malignant neoplasm of parotid gland
0.614 0.386 0.000
O66 Other obstructed labour
0.614 0.386 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.614 0.386 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.614 0.386 0.000
G92 Toxic encephalopathy
0.614 0.386 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.614 0.386 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.613 0.387 0.000
Z51.3 Blood transfusion without reported diagnosis
0.613 0.387 0.000
M35.3 Polymyalgia rheumatica
0.612 0.388 0.000
C50.5 Lower-outer quadrant of breast
0.612 0.388 0.000
L30.9 Dermatitis, unspecified
0.612 0.388 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.611 0.389 0.000
Y65.4 Failure to introduce or to remove other tube or instrument
0.610 0.390 0.000
C34.1 Upper lobe, bronchus or lung
0.610 0.390 0.000
I34.0 Mitral (valve) insufficiency
0.609 0.391 0.000
W15 Fall from cliff
0.607 0.393 0.000
I05.2 Mitral stenosis with insufficiency
0.607 0.393 0.000
M24.5 Contracture of joint
0.607 0.393 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.607 0.393 0.000
D80 Immunodeficiency with predominantly antibody defects
0.607 0.393 0.000
M46 Other inflammatory spondylopathies
0.607 0.393 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.606 0.394 0.000
L50-L54 Urticaria and erythema
0.605 0.395 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.605 0.395 0.000
Y43.3 Other antineoplastic drugs
0.604 0.396 0.000
Z43.9 Attention to unspecified artificial opening
0.604 0.396 0.000
Z43.7 Attention to artificial vagina
0.604 0.396 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.604 0.396 0.000
Z43.0 Attention to tracheostomy
0.604 0.396 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.603 0.397 0.000
O85-O92 Complications predominantly related to the puerperium
0.603 0.397 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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