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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Diagnostic term associations

Hospitalization Episode Statistics (HES)

Y10-Y34
Event of undetermined intent
Parent term
Chapter XX External causes of morbidity and mortality
Nested terms
Y10 Poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics, undetermined intent
Y11 Poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified, undetermined intent
Y12 Poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified, undetermined intent
Y13 Poisoning by and exposure to other drugs acting on the autonomic nervous system, undetermined intent
Y14 Poisoning by and exposure to other and unspecified drugs, medicaments and biological substances, undetermined intent
Y15 Poisoning by and exposure to alcohol, undetermined intent
Y16 Poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours, undetermined intent
Y17 Poisoning by and exposure to other gases and vapours, undetermined intent
Y18 Poisoning by and exposure to pesticides, undetermined intent
Y19 Poisoning by and exposure to other and unspecified chemicals and noxious substances, undetermined intent
Y20 Hanging, strangulation and suffocation, undetermined intent
Y21 Drowning and submersion, undetermined intent
Y22 Handgun discharge, undetermined intent
Y23 Rifle, shotgun and larger firearm discharge, undetermined intent
Y24 Other and unspecified firearm discharge, undetermined intent
Y25 Contact with explosive material, undetermined intent
Y26 Exposure to smoke, fire and flames, undetermined intent
Y27 Contact with steam, hot vapours and hot objects, undetermined intent
Y28 Contact with sharp object, undetermined intent
Y29 Contact with blunt object, undetermined intent
Y30 Falling, jumping or pushed from a high place, undetermined intent
Y31 Falling, lying or running before or into moving object, undetermined intent
Y32 Crashing of motor vehicle, undetermined intent
Y33 Other specified events, undetermined intent
Y34 Unspecified event, undetermined intent
What are diagnostic terms?
Variant effects

Click on a variant to see its association results.

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
rs7745040 lBF = 331.674   Chr6 : 32,664,332
0.841 0.159 0.000
rs9273502 lBF = 239.503   Chr6 : 32,628,389
0.814 0.186 0.000
rs28746867 lBF = 230.246   Chr6 : 32,635,293
0.813 0.187 0.000
rs2844480 lBF = 73.2041   Chr6 : 31,564,821
0.810 0.190 0.000
rs28724252 lBF = 242.458   Chr6 : 32,629,549
0.810 0.190 0.000
Affx-28498032 lBF = 239.951   Chr6 : 32,631,570
0.809 0.191 0.000
rs1799964 lBF = 64.3315   Chr6 : 31,542,308
0.808 0.192 0.000
rs56279505 lBF = 20.7752   Chr4 : 100,295,240
0.804 0.195 0.000
rs1130399 lBF = 228.586   Chr6 : 32,629,755
0.804 0.196 0.000
rs16920433 lBF = 8.50913   Chr9 : 4,032,693
0.790 0.210 0.000
rs6457620 lBF = 192.777   Chr6 : 32,663,999
0.788 0.212 0.000
rs6457617 lBF = 192.394   Chr6 : 32,663,851
0.787 0.213 0.000
rs9275224 lBF = 190.171   Chr6 : 32,659,878
0.785 0.215 0.000
rs16918683 lBF = 6.04179   Chr9 : 102,464,999
0.785 0.215 0.000
rs8004189 lBF = 7.62138   Chr14 : 89,394,467
0.784 0.216 0.000
rs9275292 lBF = 193.422   Chr6 : 32,663,289
0.781 0.219 0.000
rs62095487 lBF = 8.49554   Chr18 : 10,588,095
0.779 0.221 0.000
rs116560015 lBF = 10.1889   Chr11 : 51,526,911
0.777 0.223 0.000
rs2523512 lBF = 33.456   Chr6 : 31,506,801
0.776 0.224 0.000
rs2516489 lBF = 32.5039   Chr6 : 31,488,038
0.775 0.225 0.000
rs2844482 lBF = 34.6959   Chr6 : 31,539,767
0.775 0.225 0.000
rs803927 lBF = 7.65919   Chr9 : 119,403,611
0.773 0.227 0.000
rs2251824 lBF = 33.847   Chr6 : 31,511,857
0.773 0.227 0.000
rs7171171 lBF = 15.3328   Chr15 : 38,907,041
0.773 0.227 0.000
rs16967103 lBF = 14.2899   Chr15 : 38,899,190
0.772 0.228 0.000
rs2009658 lBF = 34.5004   Chr6 : 31,538,244
0.771 0.229 0.000
rs17574546 lBF = 13.6695   Chr15 : 38,902,476
0.770 0.230 0.000
rs2523503 lBF = 34.5631   Chr6 : 31,513,559
0.769 0.231 0.000
rs2516478 lBF = 31.7187   Chr6 : 31,498,737
0.768 0.232 0.000
rs2523506 lBF = 32.8524   Chr6 : 31,509,967
0.766 0.234 0.000
rs6569364 lBF = 7.02344   Chr6 : 124,158,252
0.764 0.236 0.000
rs117353933 lBF = 32.4166   Chr11 : 50,344,221
0.760 0.240 0.000
rs112476950 lBF = 5.55013   Chr7 : 138,299,824
0.759 0.240 0.000
rs73537455 lBF = 15.0818   Chr19 : 19,299,431
0.758 0.242 0.000
rs77247306 lBF = 5.19454   Chr4 : 55,682,981
0.757 0.243 0.000
rs9275338 lBF = 287.168   Chr6 : 32,667,343
0.755 0.245 0.000
rs9275312 lBF = 293.704   Chr6 : 32,665,728
0.754 0.246 0.000
rs7729458 lBF = 5.89518   Chr5 : 2,799,100
0.754 0.246 0.000
rs76858341 lBF = 24.4212   Chr11 : 50,123,910
0.751 0.249 0.000
rs2259435 lBF = 31.1222   Chr6 : 31,496,915
0.751 0.249 0.000
rs10839331 lBF = 19.4244   Chr11 : 49,701,411
0.751 0.249 0.000
rs73185805 lBF = 2.62597   Chr21 : 28,141,810
0.750 0.249 0.000
rs16914589 lBF = 19.9553   Chr11 : 49,974,670
0.750 0.250 0.000
rs41472547 lBF = 20.301   Chr11 : 49,917,671
0.750 0.250 0.000
rs7695115 lBF = 9.91959   Chr4 : 20,102,782
0.750 0.250 0.000
rs139659694 lBF = 6.68133   Chr11 : 51,108,240
0.749 0.250 0.000
rs72759465 lBF = 7.31467   Chr1 : 244,867,747
0.747 0.253 0.000
rs10226831 lBF = 8.59368   Chr7 : 38,600,741
0.747 0.253 0.000
rs57263982 lBF = 13.1493   Chr19 : 18,726,211
0.746 0.254 0.000
rs13216156 lBF = 13.8063   Chr6 : 157,390,781
0.746 0.254 0.000
rs12508440 lBF = 5.68351   Chr4 : 62,487,133
0.745 0.255 0.000
rs9275334 lBF = 329.259   Chr6 : 32,667,107
0.744 0.256 0.000
rs9275319 lBF = 298.483   Chr6 : 32,666,295
0.742 0.258 0.000
rs4420638 lBF = 199.322   Chr19 : 45,422,946
0.741 0.258 0.000
rs9273489 lBF = 297.232   Chr6 : 32,628,189
0.741 0.259 0.000
rs10424702 lBF = 9.34888   Chr19 : 19,508,013
0.740 0.260 0.000
rs10415849 lBF = 8.12617   Chr19 : 19,505,087
0.739 0.261 0.000
rs28361060 lBF = 366.643   Chr6 : 32,303,848
0.737 0.263 0.000
rs6910071 lBF = 365.296   Chr6 : 32,282,854
0.737 0.263 0.000
rs3130455 lBF = 310.319   Chr6 : 31,125,978
0.736 0.263 0.000
rs77622929 lBF = 6.08434   Chr11 : 50,634,946
0.736 0.264 0.000
rs56331483 lBF = 8.45622   Chr15 : 38,903,824
0.735 0.265 0.000
rs500044 lBF = 5.94192   Chr9 : 4,002,823
0.734 0.266 0.000
rs9272308 lBF = 332.362   Chr6 : 32,603,906
0.734 0.266 0.000
rs3130048 lBF = 290.421   Chr6 : 31,613,739
0.734 0.266 0.000
rs11534530 lBF = 5.03182   Chr11 : 54,995,116
0.734 0.266 0.000
rs1150765 lBF = 304.593   Chr6 : 31,127,562
0.733 0.267 0.000
rs9268145 lBF = 359.052   Chr6 : 32,257,284
0.733 0.267 0.000
rs1062630 lBF = 299.357   Chr6 : 31,138,107
0.732 0.268 0.000
rs130079 lBF = 308.561   Chr6 : 31,112,737
0.732 0.268 0.000
rs3916765 lBF = 217.868   Chr6 : 32,685,550
0.732 0.268 0.000
rs8033755 lBF = 6.27132   Chr15 : 28,381,546
0.731 0.269 0.000
rs2238675 lBF = 6.01595   Chr19 : 19,336,608
0.730 0.270 0.000
rs424232 lBF = 110.822   Chr6 : 32,208,324
0.729 0.271 0.000
rs56131196 lBF = 198.195   Chr19 : 45,422,846
0.728 0.272 0.000
rs11229564 lBF = 5.51228   Chr11 : 55,185,840
0.726 0.274 0.000
rs9275614 lBF = 213.979   Chr6 : 32,684,257
0.725 0.275 0.000
rs887465 lBF = 316.44   Chr6 : 31,143,652
0.724 0.276 0.000
rs9268362 lBF = 364.835   Chr6 : 32,333,341
0.723 0.277 0.000
rs34250758 lBF = 518.249   Chr6 : 32,607,376
0.723 0.277 0.000
rs1265159 lBF = 312.664   Chr6 : 31,140,047
0.723 0.277 0.000
rs3130457 lBF = 312.696   Chr6 : 31,147,194
0.723 0.277 0.000
rs1265181 lBF = 324.743   Chr6 : 31,155,785
0.722 0.277 0.000
rs6916779 lBF = 192.086   Chr6 : 32,684,317
0.720 0.280 0.000
rs1038439 lBF = 5.21812   Chr14 : 96,946,830
0.720 0.280 0.000
rs78820411 lBF = 24.1897   Chr15 : 26,478,903
0.717 0.283 0.000
rs13009537 lBF = 20.9772   Chr2 : 76,970,796
0.717 0.283 0.000
rs77196615 lBF = 18.4565   Chr19 : 45,380,335
0.717 0.283 0.000
rs117167710 lBF = 18.286   Chr19 : 49,602,287
0.717 0.283 0.000
rs62133575 lBF = 17.8576   Chr2 : 18,239,336
0.717 0.283 0.000
rs78376112 lBF = 16.3379   Chr10 : 134,761,067
0.717 0.283 0.000
rs78683487 lBF = 14.8881   Chr13 : 110,971,565
0.717 0.283 0.000
rs78108191 lBF = 14.0382   Chr11 : 87,613,189
0.717 0.283 0.000
rs73019330 lBF = 12.1394   Chr2 : 168,576,763
0.717 0.283 0.000
rs3766823 lBF = 11.995   Chr1 : 32,197,257
0.717 0.283 0.000
rs12662228 lBF = 11.7641   Chr6 : 55,191,559
0.717 0.283 0.000
rs704080 lBF = 11.6648   Chr12 : 89,749,223
0.717 0.283 0.000
rs345166 lBF = 7.71775   Chr17 : 58,209,589
0.717 0.283 0.000
rs35344500 lBF = 333.689   Chr6 : 32,609,525
0.717 0.283 0.000
rs76822006 lBF = 39.2942   Chr13 : 50,922,728
0.717 0.283 0.000
rs2814993 lBF = 37.1636   Chr6 : 34,618,893
0.717 0.283 0.000
rs2814944 lBF = 36.7641   Chr6 : 34,552,797
0.717 0.283 0.000
rs116976641 lBF = 23.6656   Chr7 : 18,277,071
0.717 0.283 0.000
rs75703265 lBF = 17.7785   Chr10 : 58,800,953
0.717 0.283 0.000
rs115624078 lBF = 17.7785   Chr6 : 15,981,550
0.717 0.283 0.000
rs118036322 lBF = 17.3823   Chr15 : 54,331,986
0.717 0.283 0.000
rs72799335 lBF = 16.5637   Chr5 : 107,878,176
0.717 0.283 0.000
rs147577476 lBF = 13.9193   Chr15 : 60,432,921
0.717 0.283 0.000
rs79633596 lBF = 13.7184   Chr4 : 185,034,015
0.717 0.283 0.000
rs4282914 lBF = 11.1942   Chr10 : 132,944,564
0.717 0.283 0.000
rs72705699 lBF = 11.092   Chr1 : 168,820,294
0.717 0.283 0.000
rs7356599 lBF = 8.25375   Chr5 : 16,877,640
0.717 0.283 0.000
Affx-19812848 lBF = 7.86531   Chr22 : 50,319,079
0.717 0.283 0.000
rs513815 lBF = 7.16067   Chr15 : 43,524,420
0.717 0.283 0.000
rs78676969 lBF = 7.12915   Chr22 : 50,319,170
0.717 0.283 0.000
rs75789659 lBF = 7.03095   Chr1 : 77,800,005
0.717 0.283 0.000
Affx-35617785 lBF = 6.99883   Chr11 : 30,751,596
0.717 0.283 0.000
rs1228075 lBF = 5.39429   Chr2 : 146,608,872
0.717 0.283 0.000
rs2744971 lBF = 35.63   Chr6 : 34,581,636
0.717 0.283 0.000
rs75238886 lBF = 22.8661   Chr17 : 34,313,612
0.717 0.283 0.000
rs74736071 lBF = 21.8989   Chr3 : 136,604,687
0.717 0.283 0.000
rs114122048 lBF = 17.5378   Chr5 : 167,787,265
0.717 0.283 0.000
rs4648 lBF = 17.381   Chr1 : 201,934,578
0.717 0.283 0.000
rs111892515 lBF = 12.0702   Chr21 : 23,392,906
0.717 0.283 0.000
rs117460072 lBF = 11.0684   Chr15 : 23,081,204
0.717 0.283 0.000
rs77168252 lBF = 9.86373   Chr11 : 128,734,360
0.717 0.283 0.000
rs117172322 lBF = 9.83651   Chr8 : 39,522,372
0.717 0.283 0.000
rs6751558 lBF = 9.74288   Chr2 : 146,592,046
0.717 0.283 0.000
rs111583183 lBF = 8.82259   Chr11 : 127,014,664
0.717 0.283 0.000
rs1035977 lBF = 8.7775   Chr2 : 57,232,308
0.717 0.283 0.000
rs61820511 lBF = 8.52267   Chr1 : 191,420,181
0.717 0.283 0.000
rs6938239 lBF = 34.3464   Chr6 : 34,683,635
0.717 0.283 0.000
rs76761043 lBF = 33.5262   Chr13 : 40,263,143
0.717 0.283 0.000
rs78789724 lBF = 20.4177   Chr2 : 201,459,445
0.717 0.283 0.000
rs76160395 lBF = 18.7233   Chr20 : 17,492,960
0.717 0.283 0.000
rs74584624 lBF = 18.2621   Chr5 : 62,106,216
0.717 0.283 0.000
rs12661855 lBF = 17.4102   Chr6 : 42,454,778
0.717 0.283 0.000
rs41313890 lBF = 16.9354   Chr1 : 201,932,181
0.717 0.283 0.000
rs9469913 lBF = 16.491   Chr6 : 34,827,085
0.717 0.283 0.000
rs61876800 lBF = 14.7878   Chr11 : 9,551,310
0.717 0.283 0.000
rs72798157 lBF = 13.8829   Chr5 : 107,430,034
0.717 0.283 0.000
rs79722283 lBF = 12.398   Chr2 : 56,869,337
0.717 0.283 0.000
rs17013679 lBF = 8.97199   Chr1 : 209,084,801
0.717 0.283 0.000
rs78165376 lBF = 8.53544   Chr3 : 177,552,699
0.717 0.283 0.000
rs74664320 lBF = 6.47555   Chr6 : 54,203,938
0.717 0.283 0.000
rs61921073 lBF = 6.44028   Chr12 : 30,660,861
0.717 0.283 0.000
rs17442634 lBF = 27.7415   Chr1 : 36,883,909
0.717 0.283 0.000
rs11108227 lBF = 16.4201   Chr12 : 96,134,001
0.717 0.283 0.000
rs117873316 lBF = 14.6834   Chr8 : 135,652,254
0.717 0.283 0.000
rs117173876 lBF = 14.6692   Chr13 : 38,647,866
0.717 0.283 0.000
rs77649004 lBF = 14.247   Chr12 : 96,135,916
0.717 0.283 0.000
rs62235665 lBF = 13.4781   Chr21 : 41,534,335
0.717 0.283 0.000
rs117987208 lBF = 12.4424   Chr13 : 101,245,012
0.717 0.283 0.000
rs17690804 lBF = 12.2799   Chr14 : 88,711,855
0.717 0.283 0.000
rs56065549 lBF = 11.9825   Chr9 : 95,906,364
0.717 0.283 0.000
rs117608348 lBF = 10.9159   Chr14 : 105,974,186
0.717 0.283 0.000
rs12898290 lBF = 8.08103   Chr15 : 31,294,343
0.717 0.283 0.000
rs11785559 lBF = 6.9921   Chr8 : 129,300,304
0.717 0.283 0.000
rs10962088 lBF = 6.0293   Chr9 : 15,591,699
0.717 0.283 0.000
rs117127725 lBF = 5.60389   Chr8 : 125,737,252
0.717 0.283 0.000
rs1243507 lBF = 18.6876   Chr14 : 95,314,433
0.717 0.283 0.000
rs78517764 lBF = 17.5971   Chr19 : 55,055,906
0.717 0.283 0.000
rs854625 lBF = 15.4246   Chr17 : 34,328,461
0.717 0.283 0.000
rs12616962 lBF = 15.3337   Chr2 : 155,628,974
0.717 0.283 0.000
rs117699411 lBF = 14.2479   Chr7 : 18,378,068
0.717 0.283 0.000
rs74203920 lBF = 13.9618   Chr21 : 45,714,294
0.717 0.283 0.000
rs17722134 lBF = 13.8489   Chr12 : 72,401,694
0.717 0.283 0.000
rs75732005 lBF = 11.1647   Chr7 : 106,623,114
0.717 0.283 0.000
rs117597017 lBF = 9.81246   Chr14 : 56,885,357
0.717 0.283 0.000
rs3784589 lBF = 6.65828   Chr15 : 31,294,714
0.717 0.283 0.000
rs12356580 lBF = 5.41793   Chr10 : 102,849,455
0.717 0.283 0.000
rs9469890 lBF = 33.5115   Chr6 : 34,763,982
0.717 0.283 0.000
rs78566849 lBF = 16.9908   Chr5 : 156,916,452
0.717 0.283 0.000
rs150097632 lBF = 16.4138   Chr21 : 40,688,518
0.717 0.283 0.000
rs117066666 lBF = 16.3713   Chr13 : 104,588,913
0.717 0.283 0.000
rs76594372 lBF = 16.0712   Chr5 : 156,821,650
0.717 0.283 0.000
rs74414776 lBF = 15.3148   Chr2 : 2,693,751
0.717 0.283 0.000
rs34242703 lBF = 10.2176   Chr22 : 45,225,346
0.717 0.283 0.000
rs62243877 lBF = 8.18156   Chr3 : 62,175,417
0.717 0.283 0.000
rs7073278 lBF = 7.5078   Chr10 : 13,859,897
0.717 0.283 0.000
rs2900174 lBF = 7.38903   Chr12 : 11,547,532
0.717 0.283 0.000
rs17485667 lBF = 7.24574   Chr9 : 131,768,191
0.717 0.283 0.000
rs12545092 lBF = 6.89488   Chr8 : 19,520,367
0.717 0.283 0.000
rs34279390 lBF = 6.72756   Chr4 : 79,527,683
0.717 0.283 0.000
rs17545824 lBF = 6.53432   Chr5 : 110,877,600
0.717 0.283 0.000
rs1636352 lBF = 6.48071   Chr7 : 149,112,189
0.717 0.283 0.000
rs12231974 lBF = 6.07834   Chr12 : 67,095,378
0.717 0.283 0.000
rs56198862 lBF = 5.18995   Chr1 : 41,172,312
0.717 0.283 0.000
rs16894959 lBF = 30.3222   Chr6 : 34,825,662
0.717 0.283 0.000
rs17127407 lBF = 21.5936   Chr14 : 23,647,729
0.717 0.283 0.000
rs114101798 lBF = 17.9738   Chr3 : 135,286,950
0.717 0.283 0.000
rs77507119 lBF = 17.3947   Chr7 : 124,093,649
0.717 0.283 0.000
rs55856550 lBF = 15.678   Chr9 : 22,364,370
0.717 0.283 0.000
rs11250485 lBF = 13.8708   Chr10 : 1,417,738
0.717 0.283 0.000
rs34616430 lBF = 13.2898   Chr4 : 34,259,163
0.717 0.283 0.000
rs17656127 lBF = 11.4413   Chr18 : 47,026,826
0.717 0.283 0.000
rs79616469 lBF = 11.2572   Chr2 : 48,875,108
0.717 0.283 0.000
rs11742133 lBF = 8.36622   Chr5 : 155,268,373
0.717 0.283 0.000
rs79470404 lBF = 28.8963   Chr3 : 136,509,875
0.717 0.283 0.000
rs72683295 lBF = 19.6099   Chr1 : 103,466,407
0.717 0.283 0.000
rs78289709 lBF = 16.6994   Chr18 : 27,498,046
0.717 0.283 0.000
rs78024203 lBF = 16.2259   Chr2 : 125,447,492
0.717 0.283 0.000
rs111715478 lBF = 14.7867   Chr2 : 100,161,578
0.717 0.283 0.000
rs77774752 lBF = 14.2158   Chr2 : 56,960,157
0.717 0.283 0.000
rs115165870 lBF = 10.7118   Chr1 : 154,303,228
0.717 0.283 0.000
rs73007766 lBF = 9.30092   Chr6 : 152,606,194
0.717 0.283 0.000
rs76653830 lBF = 9.27013   Chr16 : 84,836,091
0.717 0.283 0.000
rs68108873 lBF = 8.01808   Chr2 : 170,121,734
0.717 0.283 0.000
rs79300279 lBF = 6.41012   Chr9 : 6,133,663
0.717 0.283 0.000
rs3800461 lBF = 38.5883   Chr6 : 34,616,322
0.717 0.283 0.000
rs73026643 lBF = 26.1067   Chr11 : 118,166,597
0.717 0.283 0.000
rs67068100 lBF = 25.2032   Chr6 : 31,429,913
0.717 0.283 0.000
rs113937434 lBF = 20.1272   Chr17 : 34,313,674
0.717 0.283 0.000
rs74976411 lBF = 18.6882   Chr7 : 28,901,486
0.717 0.283 0.000
Affx-8411664 lBF = 18.4862   Chr12 : 71,094,955
0.717 0.283 0.000
rs259479 lBF = 12.9589   Chr1 : 218,746,640
0.717 0.283 0.000
rs72809231 lBF = 12.4782   Chr5 : 156,798,578
0.717 0.283 0.000
rs11985641 lBF = 11.8964   Chr8 : 2,281,867
0.717 0.283 0.000
rs75513936 lBF = 11.7791   Chr6 : 22,469,034
0.717 0.283 0.000
rs4766986 lBF = 8.99695   Chr12 : 113,076,475
0.717 0.283 0.000
rs72948168 lBF = 6.34748   Chr2 : 159,761,508
0.717 0.283 0.000
rs12378793 lBF = 6.11146   Chr9 : 79,613,935
0.717 0.283 0.000
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rs79749933 lBF = 9.58226   Chr14 : 87,560,818
0.716 0.284 0.000
rs77311400 lBF = 9.0751   Chr6 : 166,916,112
0.716 0.284 0.000
rs118027503 lBF = 5.17072   Chr18 : 77,687,518
0.716 0.284 0.000
rs3132449 lBF = 379.265   Chr6 : 31,626,013
0.716 0.284 0.000
rs3132450 lBF = 377.185   Chr6 : 31,596,138
0.716 0.284 0.000
rs78221103 lBF = 16.6479   Chr12 : 104,562,673
0.716 0.284 0.000
rs13215574 lBF = 14.0292   Chr6 : 146,006,127
0.716 0.284 0.000
rs75015734 lBF = 13.2765   Chr11 : 20,186,756
0.716 0.284 0.000
rs117650759 lBF = 12.6039   Chr18 : 7,675,399
0.716 0.284 0.000
rs72703193 lBF = 5.14866   Chr5 : 914,309
0.716 0.284 0.000
rs11230874 lBF = 4.32584   Chr11 : 61,795,586
0.716 0.284 0.000
rs1150758 lBF = 380.161   Chr6 : 32,028,149
0.716 0.284 0.000
rs117636037 lBF = 18.8537   Chr12 : 38,519,375
0.716 0.284 0.000
rs3852213 lBF = 14.0208   Chr6 : 28,732,364
0.716 0.284 0.000
rs78549223 lBF = 13.151   Chr12 : 71,168,008
0.716 0.284 0.000
rs72700262 lBF = 12.1803   Chr1 : 154,769,750
0.716 0.284 0.000
rs116078501 lBF = 9.50922   Chr2 : 8,698,802
0.716 0.284 0.000
rs116738814 lBF = 21.0352   Chr6 : 31,326,566
0.716 0.284 0.000
rs6909960 lBF = 14.5496   Chr6 : 28,688,921
0.716 0.284 0.000
rs67497292 lBF = 13.8596   Chr6 : 31,766,844
0.716 0.284 0.000
rs56183335 lBF = 6.66881   Chr5 : 141,474,886
0.716 0.284 0.000
rs3132580 lBF = 124.975   Chr6 : 30,920,124
0.716 0.284 0.000
rs76964416 lBF = 17.3421   Chr5 : 141,526,554
0.716 0.284 0.000
rs117216419 lBF = 13.1076   Chr19 : 41,700,346
0.716 0.284 0.000
rs12215963 lBF = 20.8881   Chr6 : 31,138,619
0.716 0.284 0.000
rs6830001 lBF = 14.9054   Chr4 : 109,026,801
0.716 0.284 0.000
rs114632267 lBF = 14.7346   Chr5 : 94,228,968
0.716 0.284 0.000
rs79113544 lBF = 14.4413   Chr13 : 47,580,175
0.716 0.284 0.000
rs76293282 lBF = 13.7427   Chr20 : 56,761,942
0.716 0.284 0.000
rs76594396 lBF = 11.0301   Chr8 : 5,443,735
0.716 0.284 0.000
rs11652466 lBF = 5.34235   Chr17 : 56,061,709
0.716 0.284 0.000
rs80260767 lBF = 16.4535   Chr10 : 99,803,425
0.716 0.284 0.000
rs142089946 lBF = 13.9816   Chr5 : 60,791,593
0.716 0.284 0.000
rs11051689 lBF = 13.3747   Chr12 : 32,084,827
0.716 0.284 0.000
rs8142548 lBF = 11.8001   Chr22 : 37,365,039
0.716 0.284 0.000
rs6760338 lBF = 11.3095   Chr2 : 198,711,900
0.716 0.284 0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

 
Variant clusters with highest protective effect

(posterior probability > 0.05)

Cluster X0335
log Bayes Factor = 12.3689
contains 1 variants
0.7090
Cluster X0333
log Bayes Factor = 38.671
contains 2 variants
0.2247
Variant clusters with highest risk effect

(posterior probability > 0.05)

Cluster X0035
log Bayes Factor = 620.567
contains 37 variants
0.9946
Cluster X0002
log Bayes Factor = 522.044
contains 22 variants
0.9725
Cluster X0103
log Bayes Factor = 194.456
contains 13 variants
0.9551
Cluster X0179
log Bayes Factor = 426.274
contains 17 variants
0.9057
Cluster X0195
log Bayes Factor = 167.337
contains 13 variants
0.8708
Cluster X0328
log Bayes Factor = 380.087
contains 8 variants
0.8564
Cluster X0196
log Bayes Factor = 301.726
contains 18 variants
0.8546
Cluster X0114
log Bayes Factor = 510.917
contains 25 variants
0.8469
Cluster X0236
log Bayes Factor = 83.9265
contains 3 variants
0.8429
Cluster X0020
log Bayes Factor = 557.721
contains 18 variants
0.8028
Cluster X0101
log Bayes Factor = 45.9023
contains 7 variants
0.7905
Cluster X0080
log Bayes Factor = 455.123
contains 21 variants
0.7905
Cluster X0018
log Bayes Factor = 430.611
contains 18 variants
0.7811
Cluster X0127
log Bayes Factor = 276.004
contains 14 variants
0.7806
Cluster X0226
log Bayes Factor = 145.726
contains 8 variants
0.7766
Cluster X0339
log Bayes Factor = 56.078
contains 2 variants
0.7666
Cluster X0278
log Bayes Factor = 173.437
contains 11 variants
0.7592
Cluster X0269
log Bayes Factor = 155.455
contains 9 variants
0.7573
Cluster X0297
log Bayes Factor = 63.8292
contains 4 variants
0.7552
Cluster X0169
log Bayes Factor = 331.98
contains 16 variants
0.7474
Cluster X0007
log Bayes Factor = 107.567
contains 7 variants
0.7457
Cluster X0060
log Bayes Factor = 242.413
contains 5 variants
0.7442
Cluster X0279
log Bayes Factor = 52.8832
contains 2 variants
0.7402
Cluster X0128
log Bayes Factor = 148.918
contains 15 variants
0.7398
Cluster X0160
log Bayes Factor = 99.5328
contains 9 variants
0.7380
Cluster X0270
log Bayes Factor = 41.2082
contains 4 variants
0.7261
Cluster X0011
log Bayes Factor = 138.832
contains 11 variants
0.7208
Cluster X0041
log Bayes Factor = 306.192
contains 14 variants
0.7169
Cluster X0057
log Bayes Factor = 439.35
contains 16 variants
0.7169
Cluster X0073
log Bayes Factor = 785.614
contains 25 variants
0.7169
Cluster X0089
log Bayes Factor = 308.747
contains 13 variants
0.7169
Cluster X0121
log Bayes Factor = 131.08
contains 9 variants
0.7169
Cluster X0153
log Bayes Factor = 328.394
contains 11 variants
0.7169
Cluster X0185
log Bayes Factor = 84.7127
contains 6 variants
0.7169
Cluster X0201
log Bayes Factor = 368.049
contains 13 variants
0.7169
Cluster X0249
log Bayes Factor = 244.457
contains 11 variants
0.7169
Cluster X0026
log Bayes Factor = 232.119
contains 9 variants
0.7169
Cluster X0042
log Bayes Factor = 307.243
contains 12 variants
0.7169
Cluster X0058
log Bayes Factor = 183.199
contains 8 variants
0.7169
Cluster X0074
log Bayes Factor = 353.38
contains 15 variants
0.7169
Cluster X0106
log Bayes Factor = 980.916
contains 30 variants
0.7169
Cluster X0122
log Bayes Factor = 219.114
contains 9 variants
0.7169
Cluster X0154
log Bayes Factor = 282.084
contains 12 variants
0.7169
Cluster X0170
log Bayes Factor = 264.081
contains 11 variants
0.7169
Cluster X0218
log Bayes Factor = 425.579
contains 18 variants
0.7169
Cluster X0043
log Bayes Factor = 517.108
contains 20 variants
0.7169
Cluster X0059
log Bayes Factor = 922.497
contains 26 variants
0.7169
Cluster X0075
log Bayes Factor = 431.344
contains 16 variants
0.7169
Cluster X0091
log Bayes Factor = 303.64
contains 12 variants
0.7169
Cluster X0123
log Bayes Factor = 382.779
contains 14 variants
0.7169
Cluster X0139
log Bayes Factor = 304.555
contains 10 variants
0.7169
Cluster X0155
log Bayes Factor = 348.568
contains 12 variants
0.7169
Cluster X0171
log Bayes Factor = 291.293
contains 14 variants
0.7169
Cluster X0203
log Bayes Factor = 363.522
contains 11 variants
0.7169
Cluster X0219
log Bayes Factor = 230.324
contains 15 variants
0.7169
Cluster X0267
log Bayes Factor = 92.4806
contains 5 variants
0.7169
Cluster X0283
log Bayes Factor = 162.98
contains 9 variants
0.7169
Cluster X0012
log Bayes Factor = 112.432
contains 5 variants
0.7169
Cluster X0028
log Bayes Factor = 120.445
contains 7 variants
0.7169
Cluster X0044
log Bayes Factor = 1165.44
contains 34 variants
0.7169
Cluster X0076
log Bayes Factor = 310.928
contains 15 variants
0.7169
Cluster X0124
log Bayes Factor = 336.468
contains 13 variants
0.7169
Cluster X0140
log Bayes Factor = 164.536
contains 8 variants
0.7169
Cluster X0156
log Bayes Factor = 226.954
contains 9 variants
0.7169
Cluster X0188
log Bayes Factor = 222.629
contains 14 variants
0.7169
Cluster X0204
log Bayes Factor = 169.796
contains 8 variants
0.7169
Cluster X0220
log Bayes Factor = 142.284
contains 7 variants
0.7169
Cluster X0268
log Bayes Factor = 213.591
contains 8 variants
0.7169
Cluster X0284
log Bayes Factor = 192.532
contains 9 variants
0.7169
Cluster X0332
log Bayes Factor = 65.2374
contains 3 variants
0.7169
Cluster X0013
log Bayes Factor = 548.265
contains 23 variants
0.7169
Cluster X0029
log Bayes Factor = 709.102
contains 23 variants
0.7169
Cluster X0045
log Bayes Factor = 446.264
contains 16 variants
0.7169
Cluster X0061
log Bayes Factor = 293.105
contains 15 variants
0.7169
Cluster X0077
log Bayes Factor = 571.533
contains 17 variants
0.7169
Cluster X0093
log Bayes Factor = 289.878
contains 10 variants
0.7169
Cluster X0109
log Bayes Factor = 257.685
contains 11 variants
0.7169
Cluster X0125
log Bayes Factor = 215.738
contains 7 variants
0.7169
Cluster X0141
log Bayes Factor = 742.063
contains 30 variants
0.7169
Cluster X0157
log Bayes Factor = 172.957
contains 8 variants
0.7169
Cluster X0189
log Bayes Factor = 149.681
contains 5 variants
0.7169
Cluster X0205
log Bayes Factor = 674.183
contains 18 variants
0.7169
Cluster X0221
log Bayes Factor = 149.378
contains 10 variants
0.7169
Cluster X0253
log Bayes Factor = 331.491
contains 13 variants
0.7169
Cluster X0014
log Bayes Factor = 131.677
contains 6 variants
0.7169
Cluster X0030
log Bayes Factor = 216.364
contains 9 variants
0.7169
Cluster X0046
log Bayes Factor = 387.972
contains 16 variants
0.7169
Cluster X0078
log Bayes Factor = 203.49
contains 11 variants
0.7169
Cluster X0094
log Bayes Factor = 562.956
contains 18 variants
0.7169
Cluster X0110
log Bayes Factor = 721.325
contains 13 variants
0.7169
Cluster X0126
log Bayes Factor = 384.432
contains 15 variants
0.7169
Cluster X0142
log Bayes Factor = 295.63
contains 12 variants
0.7169
Cluster X0174
log Bayes Factor = 214.209
contains 8 variants
0.7169
Cluster X0222
log Bayes Factor = 431.582
contains 17 variants
0.7169
Cluster X0238
log Bayes Factor = 97.9307
contains 4 variants
0.7169
Cluster X0015
log Bayes Factor = 356.23
contains 15 variants
0.7169
Cluster X0047
log Bayes Factor = 378.621
contains 14 variants
0.7169
Cluster X0063
log Bayes Factor = 107.557
contains 5 variants
0.7169
Cluster X0079
log Bayes Factor = 413.803
contains 22 variants
0.7169
Cluster X0095
log Bayes Factor = 179.348
contains 8 variants
0.7169
Cluster X0111
log Bayes Factor = 403.183
contains 18 variants
0.7169
Cluster X0143
log Bayes Factor = 179.808
contains 8 variants
0.7169
Cluster X0159
log Bayes Factor = 152.327
contains 7 variants
0.7169
Cluster X0191
log Bayes Factor = 163.555
contains 8 variants
0.7169
Cluster X0223
log Bayes Factor = 122.347
contains 7 variants
0.7169
Cluster X0271
log Bayes Factor = 256.743
contains 10 variants
0.7169
Cluster X0032
log Bayes Factor = 255.737
contains 12 variants
0.7169
Cluster X0048
log Bayes Factor = 358.819
contains 19 variants
0.7169
Cluster X0064
log Bayes Factor = 166.06
contains 10 variants
0.7169
Cluster X0176
log Bayes Factor = 407.797
contains 14 variants
0.7169
Cluster X0192
log Bayes Factor = 402.511
contains 14 variants
0.7169
Cluster X0224
log Bayes Factor = 278.692
contains 11 variants
0.7169
Cluster X0240
log Bayes Factor = 104.862
contains 6 variants
0.7169
Cluster X0256
log Bayes Factor = 211.588
contains 9 variants
0.7169
Cluster X0320
log Bayes Factor = 110.964
contains 6 variants
0.7169
Cluster X0001
log Bayes Factor = 167.541
contains 7 variants
0.7169
Cluster X0033
log Bayes Factor = 379.444
contains 13 variants
0.7169
Cluster X0049
log Bayes Factor = 597.061
contains 18 variants
0.7169
Cluster X0081
log Bayes Factor = 278.568
contains 10 variants
0.7169
Cluster X0145
log Bayes Factor = 274.587
contains 11 variants
0.7169
Cluster X0161
log Bayes Factor = 609.219
contains 20 variants
0.7169
Cluster X0177
log Bayes Factor = 254.872
contains 10 variants
0.7169
Cluster X0193
log Bayes Factor = 303.265
contains 16 variants
0.7169
Cluster X0209
log Bayes Factor = 214.798
contains 8 variants
0.7169
Cluster X0257
log Bayes Factor = 281.184
contains 10 variants
0.7169
Cluster X0273
log Bayes Factor = 109.896
contains 6 variants
0.7169
Cluster X0050
log Bayes Factor = 397.79
contains 16 variants
0.7169
Cluster X0082
log Bayes Factor = 496.905
contains 17 variants
0.7169
Cluster X0098
log Bayes Factor = 246.226
contains 8 variants
0.7169
Cluster X0146
log Bayes Factor = 686.343
contains 22 variants
0.7169
Cluster X0162
log Bayes Factor = 144.479
contains 9 variants
0.7169
Cluster X0178
log Bayes Factor = 225.6
contains 9 variants
0.7169
Cluster X0210
log Bayes Factor = 426.159
contains 17 variants
0.7169
Cluster X0274
log Bayes Factor = 454.783
contains 18 variants
0.7169
Cluster X0290
log Bayes Factor = 333.908
contains 13 variants
0.7169
Cluster X0003
log Bayes Factor = 195.6
contains 8 variants
0.7169
Cluster X0019
log Bayes Factor = 372.36
contains 16 variants
0.7169
Cluster X0051
log Bayes Factor = 376.793
contains 14 variants
0.7169
Cluster X0067
log Bayes Factor = 179.381
contains 8 variants
0.7169
Cluster X0083
log Bayes Factor = 351.917
contains 13 variants
0.7169
Cluster X0131
log Bayes Factor = 143.942
contains 8 variants
0.7169
Cluster X0147
log Bayes Factor = 133.509
contains 9 variants
0.7169
Cluster X0163
log Bayes Factor = 122.554
contains 6 variants
0.7169
Cluster X0227
log Bayes Factor = 249.287
contains 11 variants
0.7169
Cluster X0243
log Bayes Factor = 104.974
contains 6 variants
0.7169
Cluster X0259
log Bayes Factor = 246.237
contains 11 variants
0.7169
Cluster X0275
log Bayes Factor = 219.726
contains 10 variants
0.7169
Cluster X0052
log Bayes Factor = 654.387
contains 25 variants
0.7169
Cluster X0068
log Bayes Factor = 127.774
contains 6 variants
0.7169
Cluster X0084
log Bayes Factor = 433.078
contains 21 variants
0.7169
Cluster X0100
log Bayes Factor = 730.252
contains 26 variants
0.7169
Cluster X0132
log Bayes Factor = 267.393
contains 11 variants
0.7169
Cluster X0148
log Bayes Factor = 315.237
contains 11 variants
0.7169
Cluster X0164
log Bayes Factor = 463.793
contains 16 variants
0.7169
Cluster X0180
log Bayes Factor = 410.88
contains 15 variants
0.7169
Cluster X0212
log Bayes Factor = 300.777
contains 10 variants
0.7169
Cluster X0244
log Bayes Factor = 122.647
contains 5 variants
0.7169
Cluster X0276
log Bayes Factor = 187.108
contains 9 variants
0.7169
Cluster X0005
log Bayes Factor = 282.915
contains 11 variants
0.7169
Cluster X0021
log Bayes Factor = 338.631
contains 13 variants
0.7169
Cluster X0037
log Bayes Factor = 171.712
contains 6 variants
0.7169
Cluster X0053
log Bayes Factor = 218.825
contains 12 variants
0.7169
Cluster X0069
log Bayes Factor = 519.392
contains 20 variants
0.7169
Cluster X0117
log Bayes Factor = 453.246
contains 21 variants
0.7169
Cluster X0133
log Bayes Factor = 224.204
contains 11 variants
0.7169
Cluster X0165
log Bayes Factor = 303.727
contains 12 variants
0.7169
Cluster X0181
log Bayes Factor = 141.396
contains 6 variants
0.7169
Cluster X0197
log Bayes Factor = 158.582
contains 8 variants
0.7169
Cluster X0213
log Bayes Factor = 405.918
contains 15 variants
0.7169
Cluster X0229
log Bayes Factor = 347.165
contains 13 variants
0.7169
Cluster X0261
log Bayes Factor = 420.614
contains 20 variants
0.7169
Cluster X0277
log Bayes Factor = 726.213
contains 23 variants
0.7169
Cluster X0054
log Bayes Factor = 197.338
contains 9 variants
0.7169
Cluster X0070
log Bayes Factor = 421.182
contains 15 variants
0.7169
Cluster X0086
log Bayes Factor = 131.002
contains 8 variants
0.7169
Cluster X0102
log Bayes Factor = 99.5678
contains 5 variants
0.7169
Cluster X0118
log Bayes Factor = 91.1908
contains 5 variants
0.7169
Cluster X0134
log Bayes Factor = 151.731
contains 8 variants
0.7169
Cluster X0150
log Bayes Factor = 861.091
contains 26 variants
0.7169
Cluster X0166
log Bayes Factor = 230.746
contains 8 variants
0.7169
Cluster X0182
log Bayes Factor = 91.4459
contains 4 variants
0.7169
Cluster X0214
log Bayes Factor = 186.582
contains 8 variants
0.7169
Cluster X0230
log Bayes Factor = 131.696
contains 7 variants
0.7169
Cluster X0246
log Bayes Factor = 121.08
contains 5 variants
0.7169
Cluster X0039
log Bayes Factor = 463.231
contains 17 variants
0.7169
Cluster X0055
log Bayes Factor = 274.911
contains 10 variants
0.7169
Cluster X0071
log Bayes Factor = 131.269
contains 6 variants
0.7169
Cluster X0087
log Bayes Factor = 894.58
contains 26 variants
0.7169
Cluster X0119
log Bayes Factor = 114.358
contains 6 variants
0.7169
Cluster X0167
log Bayes Factor = 136.48
contains 6 variants
0.7169
Cluster X0231
log Bayes Factor = 82.3185
contains 5 variants
0.7169
Cluster X0247
log Bayes Factor = 98.6507
contains 6 variants
0.7169
Cluster X0263
log Bayes Factor = 240.36
contains 13 variants
0.7169
Cluster X0327
log Bayes Factor = 118.248
contains 3 variants
0.7169
Cluster X0024
log Bayes Factor = 309.44
contains 13 variants
0.7169
Cluster X0040
log Bayes Factor = 542.747
contains 16 variants
0.7169
Cluster X0072
log Bayes Factor = 1189.98
contains 37 variants
0.7169
Cluster X0088
log Bayes Factor = 243.609
contains 9 variants
0.7169
Cluster X0152
log Bayes Factor = 331.156
contains 10 variants
0.7169
Cluster X0184
log Bayes Factor = 188.416
contains 8 variants
0.7169
Cluster X0232
log Bayes Factor = 695.273
contains 23 variants
0.7169
Cluster X0248
log Bayes Factor = 254.854
contains 10 variants
0.7169
Cluster X0264
log Bayes Factor = 205.833
contains 10 variants
0.7169
Cluster X0129
log Bayes Factor = 195.809
contains 7 variants
0.7169
Cluster X0004
log Bayes Factor = 32.8452
contains 2 variants
0.7169
Cluster X0293
log Bayes Factor = 169.051
contains 7 variants
0.7169
Cluster X0300
log Bayes Factor = 109.684
contains 3 variants
0.7169
Cluster X0225
log Bayes Factor = 36.4143
contains 3 variants
0.7169
Cluster X0326
log Bayes Factor = 112.92
contains 5 variants
0.7169
Cluster X0194
log Bayes Factor = 189.9
contains 5 variants
0.7169
Cluster X0085
log Bayes Factor = 138.902
contains 6 variants
0.7168
Cluster X0038
log Bayes Factor = 31.1234
contains 2 variants
0.7168
Cluster X0137
log Bayes Factor = 120.748
contains 4 variants
0.7167
Cluster X0208
log Bayes Factor = 40.6733
contains 2 variants
0.7167
Cluster X0258
log Bayes Factor = 104.851
contains 6 variants
0.7166
Cluster X0065
log Bayes Factor = 53.0717
contains 3 variants
0.7162
Cluster X0237
log Bayes Factor = 123.902
contains 6 variants
0.7158
Cluster X0138
log Bayes Factor = 43.7891
contains 4 variants
0.7153
Cluster X0062
log Bayes Factor = 68.7461
contains 4 variants
0.7149
Cluster X0287
log Bayes Factor = 33.3095
contains 4 variants
0.7093
Cluster X0337
log Bayes Factor = 84.9395
contains 2 variants
0.7022
Cluster X0016
log Bayes Factor = 246.869
contains 16 variants
0.6985
Cluster X0027
log Bayes Factor = 25.8087
contains 2 variants
0.6937
Cluster X0120
log Bayes Factor = 79.6695
contains 4 variants
0.6927
Cluster X0217
log Bayes Factor = 26.9761
contains 3 variants
0.6913
Cluster X0173
log Bayes Factor = 654.164
contains 9 variants
0.6895
Cluster X0107
log Bayes Factor = 151.016
contains 1 variants
0.6818
Cluster X0245
log Bayes Factor = 256.009
contains 7 variants
0.6766
Cluster X0315
log Bayes Factor = 42.686
contains 2 variants
0.6612
Cluster X0250
log Bayes Factor = 43.399
contains 4 variants
0.6453
Cluster X0113
log Bayes Factor = 49.7598
contains 3 variants
0.6419
Cluster X0199
log Bayes Factor = 350.038
contains 3 variants
0.6108
Cluster X0198
log Bayes Factor = 97.078
contains 5 variants
0.6097
Cluster X0172
log Bayes Factor = 80.2701
contains 3 variants
0.5632
Cluster X0301
log Bayes Factor = 297.489
contains 2 variants
0.5548
Cluster X0295
log Bayes Factor = 122.209
contains 5 variants
0.4830
Cluster X0262
log Bayes Factor = 269.713
contains 9 variants
0.3681
Cluster X0097
log Bayes Factor = 96.1227
contains 10 variants
0.2927
Cluster X0112
log Bayes Factor = 98.8923
contains 7 variants
0.2426
Cluster X0006
log Bayes Factor = 34.113
contains 4 variants
0.2200
Cluster X0234
log Bayes Factor = 28.8983
contains 2 variants
0.2081
Cluster X0304
log Bayes Factor = 64.0127
contains 3 variants
0.1723
Cluster X0168
log Bayes Factor = 118.571
contains 7 variants
0.1593
Cluster X0330
log Bayes Factor = 183.455
contains 2 variants
0.0681
 
 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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