TreeWAS – Variant ID: rs35947721

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter XX External causes of morbidity and mortality	0.999	0.001
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.998	0.002
S00-S09 Injuries to the head	0.998	0.002
D60-D64 Aplastic and other anaemias	0.996	0.004
D64 Other anaemias	0.994	0.006
D64.9 Anaemia, unspecified	0.992	0.008
Chapter VI Diseases of the nervous system	0.992	0.008
S02 Fracture of skull and facial bones	0.986	0.014
W20-W49 Exposure to inanimate mechanical forces	0.982	0.018
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.981	0.019
Chapter IX Diseases of the circulatory system	0.977	0.023
I30-I52 Other forms of heart disease	0.971	0.029
S01 Open wound of head	0.970	0.030
Chapter V Mental and behavioural disorders	0.969	0.031
G80-G83 Cerebral palsy and other paralytic syndromes	0.957	0.043
S01.0 Open wound of scalp	0.953	0.047
Chapter I Certain infectious and parasitic diseases	0.952	0.048
B95-B98 Bacterial, viral and other infectious agents	0.946	0.054
I70-I79 Diseases of arteries, arterioles and capillaries	0.945	0.055
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.944	0.056
I35 Nonrheumatic aortic valve disorders	0.943	0.057
S02.1 Fracture of base of skull	0.942	0.058
S30 Superficial injury of abdomen, lower back and pelvis	0.941	0.059
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.940	0.060
F30-F39 Mood [affective] disorders	0.940	0.060
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.936	0.064
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.927	0.073
Chapter IV Endocrine, nutritional and metabolic diseases	0.927	0.073
D70-D77 Other diseases of blood and blood-forming organs	0.926	0.074
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.926	0.074
G00-G09 Inflammatory diseases of the central nervous system	0.925	0.075
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.924	0.076
I35.0 Aortic (valve) stenosis	0.923	0.077
I71 Aortic aneurysm and dissection	0.922	0.078
I95-I99 Other and unspecified disorders of the circulatory system	0.920	0.080
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.917	0.083
G82 Paraplegia and tetraplegia	0.914	0.086
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.912	0.088
M05-M14 Inflammatory polyarthropathies	0.911	0.089
S02.10 Fracture of base of skull (closed)	0.910	0.090
G90-G99 Other disorders of the nervous system	0.906	0.094
T51 Toxic effect of alcohol	0.901	0.099
F32 Depressive episode	0.898	0.102
E70-E90 Metabolic disorders	0.896	0.104
S32 Fracture of lumbar spine and pelvis	0.896	0.104
X50-X57 Overexertion, travel and privation	0.889	0.111
M06 Other rheumatoid arthritis	0.888	0.112
G35-G37 Demyelinating diseases of the central nervous system	0.886	0.114
D73 Diseases of spleen	0.882	0.118
I34 Nonrheumatic mitral valve disorders	0.881	0.119
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.880	0.120
M80-M85 Disorders of bone density and structure	0.875	0.125
E20-E35 Disorders of other endocrine glands	0.875	0.125
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.875	0.125
T51.0 Ethanol	0.870	0.130
T36-T50 Poisoning by drugs, medicaments and biological substances	0.868	0.132
S10-S19 Injuries to the neck	0.867	0.133
Y40 Systemic antibiotics	0.862	0.138
M81 Osteoporosis without pathological fracture	0.858	0.142
G81 Hemiplegia	0.856	0.144
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.856	0.144
I95 Hypotension	0.854	0.146
I71.3 Abdominal aortic aneurysm, ruptured	0.854	0.146
Y88 Sequelae of surgical and medical care as external cause	0.853	0.146
Chapter X Diseases of the respiratory system	0.853	0.147
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.851	0.149
E89.0 Postprocedural hypothyroidism	0.849	0.151
F32.1 Moderate depressive episode	0.845	0.155
W20 Struck by thrown, projected or falling object	0.844	0.156
W22 Striking against or struck by other objects	0.842	0.158
S02.9 Fracture of skull and facial bones, part unspecified	0.842	0.158
G93 Other disorders of brain	0.842	0.158
M06.9 Rheumatoid arthritis, unspecified	0.841	0.159
I73 Other peripheral vascular diseases	0.841	0.159
I34.1 Mitral (valve) prolapse	0.841	0.159
W29 Contact with other powered hand tools and household machinery	0.840	0.160
I49 Other cardiac arrhythmias	0.839	0.161
T00-T07 Injuries involving multiple body regions	0.837	0.163
E27 Other disorders of adrenal gland	0.837	0.163
J95-J99 Other diseases of the respiratory system	0.837	0.163
T79-T79 Certain early complications of trauma	0.836	0.164
Y43 Primarily systemic agents	0.835	0.165
E34 Other endocrine disorders	0.833	0.167
M91-M94 Chondropathies	0.832	0.168
J98 Other respiratory disorders	0.831	0.169
D62 Acute posthaemorrhagic anaemia	0.831	0.169
E40-E46 Malnutrition	0.829	0.171
S02.4 Fracture of malar and maxillary bones	0.829	0.171
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.829	0.171
Y41 Other systemic anti-infectives and antiparasitics	0.829	0.171
Y89 Sequelae of other external causes	0.825	0.175
G35 Multiple sclerosis	0.825	0.175
T14 Injury of unspecified body region	0.821	0.179
I95.1 Orthostatic hypotension	0.821	0.179
I33 Acute and subacute endocarditis	0.820	0.180
Chapter XXII Codes for special purposes	0.819	0.181
Y00-Y09 Assault	0.819	0.181
S00 Superficial injury of head	0.818	0.182
I45 Other conduction disorders	0.817	0.183
M86-M90 Other osteopathies	0.817	0.183
I37 Pulmonary valve disorders	0.816	0.184
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.814	0.186
M81.9 Osteoporosis, unspecified	0.811	0.189
F30 Manic episode	0.811	0.189
F40-F48 Neurotic, stress-related and somatoform disorders	0.810	0.190
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.808	0.192
I50 Heart failure	0.808	0.192
V95-V97 Air and space transport accidents	0.807	0.193
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.805	0.195
J98.4 Other disorders of lung	0.804	0.196
I73.0 Raynaud's syndrome	0.803	0.197
S02.5 Fracture of tooth	0.803	0.197
I99 Other and unspecified disorders of circulatory system	0.802	0.198
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.801	0.199
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.799	0.201
G91 Hydrocephalus	0.799	0.201
S02.8 Fractures of other skull and facial bones	0.797	0.202
I30 Acute pericarditis	0.797	0.203
M06.3 Rheumatoid nodule	0.797	0.203
W21 Striking against or struck by sports equipment	0.796	0.204
M05 Seropositive rheumatoid arthritis	0.796	0.204
D61 Other aplastic anaemias	0.795	0.205
G04 Encephalitis, myelitis and encephalomyelitis	0.795	0.205
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.795	0.205
D80-D89 Certain disorders involving the immune mechanism	0.794	0.206
S01.7 Multiple open wounds of head	0.793	0.207
W25 Contact with sharp glass	0.792	0.208
D73.0 Hyposplenism	0.792	0.208
D75 Other diseases of blood and blood-forming organs	0.791	0.209
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.789	0.211
V20-V29 Motorcycle rider injured in transport accident	0.787	0.212
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.787	0.213
I49.9 Cardiac arrhythmia, unspecified	0.785	0.215
G81.9 Hemiplegia, unspecified	0.784	0.216
G82.1 Spastic paraplegia	0.783	0.217
I45.6 Preexcitation syndrome	0.782	0.218
G30-G32 Other degenerative diseases of the nervous system	0.782	0.218
I42 Cardiomyopathy	0.780	0.220
X51 Travel and motion	0.780	0.220
I71.0 Dissection of aorta [any part]	0.780	0.220
Y40.8 Other systemic antibiotics	0.780	0.220
S01.8 Open wound of other parts of head	0.780	0.220
S32.7 Multiple fractures of lumbar spine and pelvis	0.779	0.221
E27.1 Primary adrenocortical insufficiency	0.776	0.224
B15-B19 Viral hepatitis	0.776	0.224
Y43.3 Other antineoplastic drugs	0.774	0.226
E34.9 Endocrine disorder, unspecified	0.773	0.227
W75-W84 Other accidental threats to breathing	0.769	0.230
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.769	0.231
S02.3 Fracture of orbital floor	0.769	0.231
A15-A19 Tuberculosis	0.768	0.232
G82.2 Paraplegia, unspecified	0.768	0.232
S12 Fracture of neck	0.767	0.233
S31 Open wound of abdomen, lower back and pelvis	0.767	0.233
M94 Other disorders of cartilage	0.767	0.233
W00-W19 Falls	0.766	0.234
B20-B24 Human immunodeficiency virus [HIV] disease	0.765	0.235
I74 Arterial embolism and thrombosis	0.761	0.239
I00-I02 Acute rheumatic fever	0.760	0.239
I35.9 Aortic valve disorder, unspecified	0.760	0.240
T43.0 Tricyclic and tetracyclic antidepressants	0.759	0.241
E46 Unspecified protein-energy malnutrition	0.759	0.241
J98.1 Pulmonary collapse	0.759	0.241
T51.9 Alcohol, unspecified	0.759	0.241
G82.5 Tetraplegia, unspecified	0.758	0.242
I49.4 Other and unspecified premature depolarisation	0.758	0.242
M60-M63 Disorders of muscles	0.758	0.242
F31 Bipolar affective disorder	0.758	0.242
I35.1 Aortic (valve) insufficiency	0.757	0.243
M81.99 Osteoporosis, unspecified (Site unspecified)	0.756	0.244
T13 Other injuries of lower limb, level unspecified	0.755	0.245
E89.3 Postprocedural hypopituitarism	0.754	0.246
S01.3 Open wound of ear	0.754	0.246
T20-T25 Burns and corrosions of external body surface, specified by site	0.753	0.247
W45 Foreign body or object entering through skin	0.752	0.248
F99-F99 Unspecified mental disorder	0.752	0.248
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.751	0.249
Y40.6 Rifamycins	0.751	0.249
Y46 Antiepileptics and anti-Parkinsonism drugs	0.751	0.249
M81.4 Drug-induced osteoporosis	0.751	0.249
G00 Bacterial meningitis, not elsewhere classified	0.749	0.251
G03 Meningitis due to other and unspecified causes	0.749	0.251
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.748	0.252
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.748	0.252
E85 Amyloidosis	0.746	0.254
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.746	0.254
G93.9 Disorder of brain, unspecified	0.746	0.254
W20.0 Home	0.746	0.254
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.745	0.255
F32.2 Severe depressive episode without psychotic symptoms	0.744	0.256
V01-V09 Pedestrian injured in transport accident	0.744	0.256
I72 Other aneurysm	0.743	0.257
S30.0 Contusion of lower back and pelvis	0.742	0.258
M89 Other disorders of bone	0.741	0.259
Y89.9 Sequelae of unspecified external cause	0.740	0.260
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.739	0.261
F00-F09 Organic, including symptomatic, mental disorders	0.739	0.261
W29.9 Unspecified place	0.738	0.262
G82.4 Spastic tetraplegia	0.737	0.262
S06 Intracranial injury	0.737	0.263
D73.5 Infarction of spleen	0.736	0.263
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.736	0.264
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.736	0.264
T93 Sequelae of injuries of lower limb	0.734	0.266
S32.4 Fracture of acetabulum	0.734	0.266
I35.8 Other aortic valve disorders	0.731	0.269
T66-T78 Other and unspecified effects of external causes	0.730	0.269
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.730	0.270
V98-V99 Other and unspecified transport accidents	0.729	0.271
B90-B94 Sequelae of infectious and parasitic diseases	0.729	0.271
X10-X19 Contact with heat and hot substances	0.726	0.273
V80-V89 Other land transport accidents	0.726	0.274
S32.5 Fracture of pubis	0.724	0.276
W22.9 Unspecified place	0.723	0.277
W44 Foreign body entering into or through eye or natural orifice	0.723	0.277
F60-F69 Disorders of adult personality and behaviour	0.723	0.277
V10-V19 Pedal cyclist injured in transport accident	0.721	0.279
X40-X49 Accidental poisoning by and exposure to noxious substances	0.719	0.281
F30.9 Manic episode, unspecified	0.719	0.281
D64.8 Other specified anaemias	0.718	0.281
T79 Certain early complications of trauma, not elsewhere classified	0.718	0.281
M12 Other specific arthropathies	0.718	0.282
E88 Other metabolic disorders	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T00 Superficial injuries involving multiple body regions	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
S02.40 Fracture of malar and maxillary bones (closed)	0.716	0.284
Y35-Y36 Legal intervention and operations of war	0.716	0.284
Y10-Y34 Event of undetermined intent	0.716	0.284
X85-X99 Assault	0.716	0.284
X30-X39 Exposure to forces of nature	0.716	0.284
X00-X09 Exposure to smoke, fire and flames	0.716	0.284
W65-W74 Accidental drowning and submersion	0.716	0.284
V90-V94 Water transport accidents	0.716	0.284
V70-V79 Bus occupant injured in transport accident	0.716	0.284
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.716	0.284
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.716	0.284
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.716	0.284
I95.0 Idiopathic hypotension	0.716	0.284
S08 Traumatic amputation of part of head	0.715	0.285
S07 Crushing injury of head	0.715	0.285
S04 Injury of cranial nerves	0.715	0.285
S03 Dislocation, sprain and strain of joints and ligaments of head	0.715	0.285
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.714	0.286
Q80-Q89 Other congenital malformations	0.714	0.286
M05.9 Seropositive rheumatoid arthritis, unspecified	0.713	0.287
T43.4 Butyrophenone and thioxanthene neuroleptics	0.713	0.287
D75.8 Other specified diseases of blood and blood-forming organs	0.713	0.287
D64.4 Congenital dyserythropoietic anaemia	0.712	0.287
D64.3 Other sideroblastic anaemias	0.712	0.287
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.712	0.287
D64.1 Secondary sideroblastic anaemia due to disease	0.712	0.287
D64.0 Hereditary sideroblastic anaemia	0.712	0.287
I98 Other disorders of circulatory system in diseases classified elsewhere	0.712	0.288
G80 Infantile cerebral palsy	0.712	0.288
T11 Other injuries of upper limb, level unspecified	0.712	0.288
M06.0 Seronegative rheumatoid arthritis	0.712	0.288
W49 Exposure to other and unspecified inanimate mechanical forces	0.711	0.289
M94.8 Other specified disorders of cartilage	0.711	0.289
E27.9 Disorder of adrenal gland, unspecified	0.710	0.290
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.709	0.291
D55-D59 Haemolytic anaemias	0.708	0.292
S02.7 Multiple fractures involving skull and facial bones	0.707	0.293
X50 Overexertion and strenuous or repetitive movements	0.707	0.293
A80-A89 Viral infections of the central nervous system	0.707	0.293
Y09 Assault by unspecified means	0.705	0.295
W46 Contact with hypodermic needle	0.704	0.296
W43 Exposure to vibration	0.704	0.296
W42 Exposure to noise	0.704	0.296
W41 Exposure to high-pressure jet	0.704	0.296
W40 Explosion of other materials	0.704	0.296
W39 Discharge of firework	0.704	0.296
W38 Explosion and rupture of other specified pressurised devices	0.704	0.296
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.704	0.296
W36 Explosion and rupture of gas cylinder	0.704	0.296
W35 Explosion and rupture of boiler	0.704	0.296
W34 Discharge from other and unspecified firearms	0.704	0.296
W33 Rifle, shotgun and larger firearm discharge	0.704	0.296
W32 Handgun discharge	0.704	0.296
W31 Contact with other and unspecified machinery	0.704	0.296
W30 Contact with agricultural machinery	0.704	0.296
W28 Contact with powered lawn mower	0.704	0.296
W27 Contact with nonpowered hand tool	0.704	0.296
W26 Contact with knife, sword or dagger	0.704	0.296
W24 Contact with lifting and transmission devices, not elsewhere classified	0.704	0.296
W23 Caught, crushed, jammed or pinched in or between objects	0.704	0.296
I37.1 Pulmonary valve insufficiency	0.704	0.296
G94 Other disorders of brain in diseases classified elsewhere	0.704	0.296
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.703	0.297
S37 Injury of urinary and pelvic organs	0.703	0.297
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.703	0.297
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.703	0.297
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.703	0.297
Q20-Q28 Congenital malformations of the circulatory system	0.703	0.297
X51.9 Unspecified place	0.702	0.298
G01 Meningitis in bacterial diseases classified elsewhere	0.702	0.298
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.702	0.298
Q00-Q07 Congenital malformations of the nervous system	0.701	0.299
A65-A69 Other spirochaetal diseases	0.699	0.301
M85 Other disorders of bone density and structure	0.699	0.301
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.699	0.301
G93.6 Cerebral oedema	0.697	0.303
I50.0 Congestive heart failure	0.697	0.303
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.697	0.303
E89.2 Postprocedural hypoparathyroidism	0.697	0.303
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.696	0.304
I52 Other heart disorders in diseases classified elsewhere	0.696	0.304
I48 Atrial fibrillation and flutter	0.696	0.304
I43 Cardiomyopathy in diseases classified elsewhere	0.696	0.304
I41 Myocarditis in diseases classified elsewhere	0.696	0.304
I40 Acute myocarditis	0.696	0.304
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.696	0.304
I32 Pericarditis in diseases classified elsewhere	0.696	0.304
S36 Injury of intra-abdominal organs	0.696	0.304
Y41.0 Sulphonamides	0.695	0.304
G93.4 Encephalopathy, unspecified	0.695	0.305
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.695	0.305
F70-F79 Mental retardation	0.695	0.305
S30.1 Contusion of abdominal wall	0.695	0.305
M81.90 Osteoporosis, unspecified (Multiple sites)	0.695	0.305
Y43.4 Immunosuppressive agents	0.694	0.306
E27.2 Addisonian crisis	0.694	0.306
E80 Disorders of porphyrin and bilirubin metabolism	0.694	0.306
Y40.3 Macrolides	0.694	0.306
B18 Chronic viral hepatitis	0.693	0.307
E34.0 Carcinoid syndrome	0.693	0.307
G93.3 Postviral fatigue syndrome	0.692	0.308
T15-T19 Effects of foreign body entering through natural orifice	0.689	0.310
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.689	0.311
D73.4 Cyst of spleen	0.687	0.312
F41 Other anxiety disorders	0.687	0.313
J98.5 Diseases of mediastinum, not elsewhere classified	0.687	0.313
S00.8 Superficial injury of other parts of head	0.687	0.313
Y86 Sequelae of other accidents	0.687	0.313
J80-J84 Other respiratory diseases principally affecting the interstitium	0.686	0.314
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.686	0.314
U89 Agent resistant to other and unspecified antibiotics	0.684	0.316
S05 Injury of eye and orbit	0.684	0.316
D73.8 Other diseases of spleen	0.684	0.316
Y41.1 Antimycobacterial drugs	0.683	0.317
Y53 Agents primarily affecting the gastro-intestinal system	0.683	0.317
M11 Other crystal arthropathies	0.683	0.317
S01.2 Open wound of nose	0.683	0.317
B85-B89 Pediculosis, acariasis and other infestations	0.682	0.318
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.682	0.318
A75-A79 Rickettsioses	0.682	0.318
A70-A74 Other diseases caused by chlamydiae	0.682	0.318
A20-A28 Certain zoonotic bacterial diseases	0.682	0.318
E74 Other disorders of carbohydrate metabolism	0.682	0.318
G30 Alzheimer's disease	0.682	0.318
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.682	0.318
T92 Sequelae of injuries of upper limb	0.681	0.319
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.680	0.320
I46 Cardiac arrest	0.679	0.321
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.678	0.322
M81.2 Osteoporosis of disuse	0.677	0.323
G90 Disorders of autonomic nervous system	0.676	0.323
S12.2 Fracture of other specified cervical vertebra	0.676	0.324
S01.1 Open wound of eyelid and periocular area	0.676	0.324
F32.0 Mild depressive episode	0.676	0.324
S02.11 Fracture of base of skull (open)	0.675	0.325
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.674	0.326
F32.3 Severe depressive episode with psychotic symptoms	0.674	0.326
M14 Arthropathies in other diseases classified elsewhere	0.674	0.326
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.674	0.326
F38 Other mood [affective] disorders	0.674	0.326
T93.9 Sequelae of unspecified injury of lower limb	0.673	0.327
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.672	0.327
F39 Unspecified mood [affective] disorder	0.672	0.328
S02.50 Fracture of tooth (closed)	0.672	0.328
I95.8 Other hypotension	0.672	0.328
T46 Poisoning by agents primarily affecting the cardiovascular system	0.671	0.329
X58-X59 Accidental exposure to other and unspecified factors	0.670	0.330
S20-S29 Injuries to the thorax	0.670	0.330
T14.1 Open wound of unspecified body region	0.670	0.330
Y40.9 Systemic antibiotic, unspecified	0.669	0.331
V96 Accident to nonpowered aircraft causing injury to occupant	0.669	0.331
I70 Atherosclerosis	0.668	0.331
G93.5 Compression of brain	0.668	0.332
T14.6 Injury of tendons and muscles of unspecified body region	0.667	0.333
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.665	0.335
D74 Methaemoglobinaemia	0.664	0.336
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.664	0.336
D71 Functional disorders of polymorphonuclear neutrophils	0.664	0.336
I33.9 Acute endocarditis, unspecified	0.664	0.336
T65 Toxic effect of other and unspecified substances	0.664	0.336
T62 Toxic effect of other noxious substances eaten as food	0.664	0.336
T61 Toxic effect of noxious substances eaten as seafood	0.664	0.336
T60 Toxic effect of pesticides	0.664	0.336
T57 Toxic effect of other inorganic substances	0.664	0.336
T56 Toxic effect of metals	0.664	0.336
T54 Toxic effect of corrosive substances	0.664	0.336
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.664	0.336
T52 Toxic effect of organic solvents	0.664	0.336
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.664	0.336
T55 Toxic effect of soaps and detergents	0.664	0.336
F80-F89 Disorders of psychological development	0.663	0.336
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.663	0.337
G09 Sequelae of inflammatory diseases of central nervous system	0.663	0.337
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.663	0.337
W21.9 Unspecified place	0.663	0.337
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.663	0.337
T09 Other injuries of spine and trunk, level unspecified	0.663	0.337
T12.X1 Fracture of lower limb, level unspecified (open)	0.663	0.337
T12.X0 Fracture of lower limb, level unspecified (closed)	0.663	0.337
T12 Fracture of lower limb, level unspecified	0.663	0.337
T10.X1 Fracture of upper limb, level unspecified (open)	0.663	0.337
T10.X0 Fracture of upper limb, level unspecified (closed)	0.663	0.337
T10 Fracture of upper limb, level unspecified	0.663	0.337
T08.X1 Fracture of spine, level unspecified (open)	0.663	0.337
T08.X0 Fracture of spine, level unspecified (closed)	0.663	0.337
T08 Fracture of spine, level unspecified	0.663	0.337
S70-S79 Injuries to the hip and thigh	0.662	0.338
S02.80 Fractures of other skull and facial bones (closed)	0.662	0.338
M06.37 Rheumatoid nodule (Ankle and foot)	0.661	0.339
I71.8 Aortic aneurysm of unspecified site, ruptured	0.661	0.339
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.661	0.339
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.661	0.339
I71.1 Thoracic aortic aneurysm, ruptured	0.661	0.339
S02.2 Fracture of nasal bones	0.661	0.339
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.661	0.339
Y48 Anaesthetics and therapeutic gases	0.661	0.339
S06.5 Traumatic subdural haemorrhage	0.660	0.340
I33.0 Acute and subacute infective endocarditis	0.660	0.340
G91.9 Hydrocephalus, unspecified	0.658	0.342
X60-X84 Intentional self-harm	0.658	0.342
I42.9 Cardiomyopathy, unspecified	0.658	0.342
Y59 Other and unspecified vaccines and biological substances	0.657	0.342
Y58 Bacterial vaccines	0.657	0.342
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.657	0.342
Y50 Central nervous system stimulants, not elsewhere classified	0.657	0.342
Y47 Sedatives, hypnotics and antianxiety drugs	0.657	0.342
S02.0 Fracture of vault of skull	0.657	0.342
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.657	0.343
M81.40 Drug-induced osteoporosis (Multiple sites)	0.657	0.343
J98.2 Interstitial emphysema	0.656	0.344
W25.9 Unspecified place	0.656	0.344
M00-M03 Infectious arthropathies	0.656	0.344
S00.1 Contusion of eyelid and periocular area	0.656	0.344
G82.3 Flaccid tetraplegia	0.655	0.344
G82.0 Flaccid paraplegia	0.655	0.344
X20-X29 Contact with venomous animals and plants	0.655	0.344
I38 Endocarditis, valve unspecified	0.655	0.344
M81.0 Postmenopausal osteoporosis	0.655	0.345
S32.1 Fracture of sacrum	0.655	0.345
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.654	0.346
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.654	0.346
Y49 Psychotropic drugs, not elsewhere classified	0.653	0.347
M09 Juvenile arthritis in diseases classified elsewhere	0.653	0.347
M08 Juvenile arthritis	0.653	0.347
W10 Fall on and from stairs and steps	0.653	0.347
I74.5 Embolism and thrombosis of iliac artery	0.653	0.347
E86 Volume depletion	0.652	0.348
J09-J18 Influenza and pneumonia	0.652	0.348
G93.1 Anoxic brain damage, not elsewhere classified	0.652	0.348
T79.3 Post-traumatic wound infection, not elsewhere classified	0.652	0.348
Y57 Other and unspecified drugs and medicaments	0.652	0.348
G06 Intracranial and intraspinal abscess and granuloma	0.651	0.348
I42.1 Obstructive hypertrophic cardiomyopathy	0.651	0.349
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.650	0.350
S32.3 Fracture of ilium	0.650	0.350
G98 Other disorders of nervous system, not elsewhere classified	0.650	0.350
G92 Toxic encephalopathy	0.650	0.350
M06.34 Rheumatoid nodule (Hand)	0.649	0.351
T14.0 Superficial injury of unspecified body region	0.649	0.351
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.648	0.352
G91.1 Obstructive hydrocephalus	0.647	0.353
E27.8 Other specified disorders of adrenal gland	0.647	0.353
T51.8 Other alcohols	0.646	0.354
T51.3 Fusel oil	0.646	0.354
T51.2 2-Propanol	0.646	0.354
T51.1 Methanol	0.646	0.354
F44 Dissociative [conversion] disorders	0.646	0.354
J98.9 Respiratory disorder, unspecified	0.646	0.354
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.645	0.355
D86 Sarcoidosis	0.645	0.355
S00.3 Superficial injury of nose	0.645	0.355
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.644	0.355
F32.8 Other depressive episodes	0.644	0.356
B50-B64 Protozoal diseases	0.643	0.357
M86 Osteomyelitis	0.643	0.357
A50-A64 Infections with a predominantly sexual mode of transmission	0.643	0.357
E84 Cystic fibrosis	0.643	0.357
E79 Disorders of purine and pyrimidine metabolism	0.643	0.357
E77 Disorders of glycoprotein metabolism	0.643	0.357
E76 Disorders of glycosaminoglycan metabolism	0.643	0.357
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.643	0.357
E72 Other disorders of amino-acid metabolism	0.643	0.357
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.643	0.357
E70 Disorders of aromatic amino-acid metabolism	0.643	0.357
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.643	0.357
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.642	0.358
S32.2 Fracture of coccyx	0.642	0.358
I30.1 Infective pericarditis	0.642	0.358
W22.5 Trade and service area	0.642	0.358
M91 Juvenile osteochondrosis of hip and pelvis	0.642	0.358
S19 Other and unspecified injuries of neck	0.641	0.359

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations