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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76160395
log Bayes Factor = 18.7233
Chromosome 20   position 17,492,960  (GRCh37) Explore rs76160395 on Ensembl!
Variant rs76160395 is part of Cluster X0243

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.000 0.000 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.000 0.000 0.000
Y83.1 Surgical operation with implant of artificial internal device
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
B95-B98 Bacterial, viral and other infectious agents
0.999 0.001 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
Chapter II Neoplasms
0.996 0.004 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.996 0.004 0.000
T81 Complications of procedures, not elsewhere classified
0.994 0.006 0.000
M25 Other joint disorders, not elsewhere classified
0.993 0.007 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.987 0.013 0.000
Chapter IX Diseases of the circulatory system
0.987 0.013 0.000
H30-H36 Disorders of choroid and retina
0.987 0.013 0.000
I30-I52 Other forms of heart disease
0.983 0.017 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.981 0.019 0.000
H35 Other retinal disorders
0.980 0.020 0.000
M20 Acquired deformities of fingers and toes
0.979 0.021 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.966 0.034 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.966 0.034 0.000
M25.5 Pain in joint
0.955 0.045 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.954 0.046 0.000
H35.3 Degeneration of macula and posterior pole
0.950 0.050 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.949 0.051 0.000
Chapter X Diseases of the respiratory system
0.949 0.051 0.000
Y83.8 Other surgical procedures
0.946 0.054 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.945 0.055 0.000
M20.1 Hallux valgus (acquired)
0.938 0.062 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.935 0.065 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.928 0.072 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.928 0.072 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.928 0.072 0.000
E10-E14 Diabetes mellitus
0.923 0.077 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.922 0.078 0.000
C50-C50 Malignant neoplasm of breast
0.920 0.080 0.000
M20.4 Other hammer toe(s) (acquired)
0.919 0.081 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.916 0.084 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.915 0.085 0.000
I34 Nonrheumatic mitral valve disorders
0.915 0.085 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.915 0.085 0.000
J40-J47 Chronic lower respiratory diseases
0.914 0.086 0.000
Chapter VI Diseases of the nervous system
0.911 0.089 0.000
M15-M19 Arthrosis
0.909 0.091 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.906 0.094 0.000
M70-M79 Other soft tissue disorders
0.903 0.097 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.902 0.098 0.000
I05-I09 Chronic rheumatic heart diseases
0.896 0.103 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.894 0.106 0.000
C78.7 Secondary malignant neoplasm of liver
0.891 0.109 0.000
E14 Unspecified diabetes mellitus
0.890 0.110 0.000
Chapter XXII Codes for special purposes
0.889 0.111 0.000
M80-M85 Disorders of bone density and structure
0.887 0.113 0.000
I45 Other conduction disorders
0.886 0.114 0.000
M25.7 Osteophyte
0.886 0.114 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.884 0.116 0.000
H35.6 Retinal haemorrhage
0.879 0.121 0.000
I34.0 Mitral (valve) insufficiency
0.878 0.122 0.000
J95-J99 Other diseases of the respiratory system
0.876 0.124 0.000
D00-D09 In situ neoplasms
0.874 0.126 0.000
J44 Other chronic obstructive pulmonary disease
0.870 0.130 0.000
C50 Malignant neoplasm of breast
0.866 0.134 0.000
J43 Emphysema
0.866 0.134 0.000
M25.56 Pain in joint (Lower leg)
0.864 0.136 0.000
H55-H59 Other disorders of eye and adnexa
0.863 0.137 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.860 0.140 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.859 0.141 0.000
M75 Shoulder lesions
0.856 0.144 0.000
E14.9 Without complications
0.852 0.148 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.852 0.148 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.849 0.150 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.849 0.151 0.000
G90-G99 Other disorders of the nervous system
0.840 0.160 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.838 0.162 0.000
E10 Insulin-dependent diabetes mellitus
0.837 0.163 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.834 0.166 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.832 0.167 0.000
J43.9 Emphysema, unspecified
0.832 0.168 0.000
M25.4 Effusion of joint
0.831 0.169 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.831 0.169 0.000
C34 Malignant neoplasm of bronchus and lung
0.829 0.171 0.000
H52 Disorders of refraction and accommodation
0.829 0.171 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.825 0.175 0.000
B15-B19 Viral hepatitis
0.823 0.177 0.000
I38 Endocarditis, valve unspecified
0.823 0.177 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.822 0.178 0.000
M25.8 Other specified joint disorders
0.819 0.181 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.816 0.184 0.000
I35 Nonrheumatic aortic valve disorders
0.816 0.184 0.000
M65-M68 Disorders of synovium and tendon
0.813 0.186 0.000
M22 Disorders of patella
0.812 0.188 0.000
C79 Secondary malignant neoplasm of other sites
0.811 0.189 0.000
M75.4 Impingement syndrome of shoulder
0.811 0.189 0.000
I49 Other cardiac arrhythmias
0.811 0.189 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.809 0.191 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.809 0.191 0.000
C50.2 Upper-inner quadrant of breast
0.808 0.192 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.808 0.192 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.806 0.194 0.000
H33 Retinal detachments and breaks
0.806 0.194 0.000
M23 Internal derangement of knee
0.805 0.195 0.000
H35.8 Other specified retinal disorders
0.803 0.197 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.801 0.199 0.000
I51 Complications and ill-defined descriptions of heart disease
0.801 0.199 0.000
M86-M90 Other osteopathies
0.800 0.200 0.000
J98 Other respiratory disorders
0.799 0.201 0.000
D50-D53 Nutritional anaemias
0.795 0.205 0.000
Y83.9 Surgical procedure, unspecified
0.795 0.205 0.000
M25.52 Pain in joint (Upper arm)
0.794 0.206 0.000
B35-B49 Mycoses
0.794 0.206 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.793 0.207 0.000
H25-H28 Disorders of lens
0.791 0.209 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.789 0.211 0.000
W20-W49 Exposure to inanimate mechanical forces
0.788 0.212 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.787 0.213 0.000
M25.53 Pain in joint (Forearm)
0.786 0.214 0.000
M19 Other arthrosis
0.785 0.215 0.000
I08 Multiple valve diseases
0.784 0.216 0.000
C80 Malignant neoplasm without specification of site
0.783 0.217 0.000
S40-S49 Injuries to the shoulder and upper arm
0.781 0.219 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.780 0.220 0.000
I45.1 Other and unspecified right bundle-branch block
0.780 0.220 0.000
M81 Osteoporosis without pathological fracture
0.776 0.224 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.775 0.225 0.000
H52.1 Myopia
0.774 0.226 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.774 0.226 0.000
J47 Bronchiectasis
0.774 0.226 0.000
M45-M49 Spondylopathies
0.774 0.226 0.000
M40-M43 Deforming dorsopathies
0.773 0.227 0.000
H35.4 Peripheral retinal degeneration
0.773 0.227 0.000
X60-X84 Intentional self-harm
0.773 0.227 0.000
C32 Malignant neoplasm of larynx
0.772 0.228 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.772 0.228 0.000
T86 Failure and rejection of transplanted organs and tissues
0.771 0.229 0.000
D80-D89 Certain disorders involving the immune mechanism
0.768 0.232 0.000
I37 Pulmonary valve disorders
0.768 0.232 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.767 0.233 0.000
M34 Systemic sclerosis
0.767 0.233 0.000
S70-S79 Injuries to the hip and thigh
0.766 0.234 0.000
Chapter V Mental and behavioural disorders
0.766 0.234 0.000
C50.8 Overlapping lesion of breast
0.765 0.235 0.000
J60-J70 Lung diseases due to external agents
0.765 0.235 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.765 0.235 0.000
Y83.0 Surgical operation with transplant of whole organ
0.764 0.236 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.764 0.236 0.000
I44 Atrioventricular and left bundle-branch block
0.763 0.237 0.000
X20-X29 Contact with venomous animals and plants
0.762 0.238 0.000
E10.9 Without complications
0.761 0.239 0.000
H40-H42 Glaucoma
0.761 0.239 0.000
V10-V19 Pedal cyclist injured in transport accident
0.761 0.239 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.760 0.240 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.759 0.241 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.757 0.243 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.757 0.243 0.000
M17 Gonarthrosis [arthrosis of knee]
0.756 0.244 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.756 0.244 0.000
E70-E90 Metabolic disorders
0.756 0.244 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.755 0.245 0.000
I33 Acute and subacute endocarditis
0.755 0.245 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.755 0.245 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.754 0.246 0.000
Chapter VIII Diseases of the ear and mastoid process
0.754 0.246 0.000
D72 Other disorders of white blood cells
0.754 0.246 0.000
C34.9 Bronchus or lung, unspecified
0.753 0.247 0.000
H57 Other disorders of eye and adnexa
0.753 0.247 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.752 0.248 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.751 0.249 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.751 0.249 0.000
I07 Rheumatic tricuspid valve diseases
0.751 0.249 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.750 0.250 0.000
G30-G32 Other degenerative diseases of the nervous system
0.750 0.250 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.749 0.251 0.000
Y84.8 Other medical procedures
0.749 0.251 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.749 0.251 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.744 0.256 0.000
M18 Arthrosis of first carpometacarpal joint
0.744 0.256 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.738 0.261 0.000
M00-M03 Infectious arthropathies
0.738 0.262 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.738 0.262 0.000
E14.3 With ophthalmic complications
0.738 0.262 0.000
H33.0 Retinal detachment with retinal break
0.736 0.264 0.000
G35 Multiple sclerosis
0.735 0.265 0.000
Y84.6 Urinary catheterisation
0.735 0.265 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.735 0.265 0.000
M19.0 Primary arthrosis of other joints
0.731 0.269 0.000
D09 Carcinoma in situ of other and unspecified sites
0.728 0.272 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.727 0.273 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.726 0.273 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.726 0.274 0.000
M25.76 Osteophyte (Lower leg)
0.726 0.274 0.000
G93 Other disorders of brain
0.726 0.274 0.000
T88.4 Failed or difficult intubation
0.725 0.275 0.000
H49 Paralytic strabismus
0.724 0.276 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.724 0.276 0.000
S90-S99 Injuries to the ankle and foot
0.724 0.276 0.000
C71 Malignant neoplasm of brain
0.723 0.277 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.723 0.277 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.722 0.278 0.000
M25.57 Pain in joint (Ankle and foot)
0.721 0.279 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.721 0.279 0.000
C78.2 Secondary malignant neoplasm of pleura
0.720 0.280 0.000
D55-D59 Haemolytic anaemias
0.719 0.281 0.000
Y84.0 Cardiac catheterisation
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.717 0.283 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V20-V29 Motorcycle rider injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
Y83.5 Amputation of limb(s)
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M25.51 Pain in joint (Shoulder region)
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
M21 Other acquired deformities of limbs
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.716 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.283 0.000
B65-B83 Helminthiases
0.716 0.283 0.000
B50-B64 Protozoal diseases
0.716 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.283 0.000
A75-A79 Rickettsioses
0.716 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.283 0.000
A65-A69 Other spirochaetal diseases
0.716 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.283 0.000
A15-A19 Tuberculosis
0.716 0.283 0.000
H35.0 Background retinopathy and retinal vascular changes
0.716 0.284 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.716 0.284 0.000
M65 Synovitis and tenosynovitis
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
Y83.4 Other reconstructive surgery
0.714 0.286 0.000
M25.71 Osteophyte (Shoulder region)
0.714 0.286 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.714 0.286 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.714 0.286 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.714 0.286 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.714 0.286 0.000
I46 Cardiac arrest
0.713 0.286 0.000
S20-S29 Injuries to the thorax
0.713 0.286 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.713 0.287 0.000
M20.0 Deformity of finger(s)
0.713 0.287 0.000
H10-H13 Disorders of conjunctiva
0.713 0.287 0.000
T81.9 Unspecified complication of procedure
0.712 0.287 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.712 0.287 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.712 0.287 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.712 0.287 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.712 0.287 0.000
C64-C68 Malignant neoplasms of urinary tract
0.712 0.287 0.000
E40-E46 Malnutrition
0.712 0.288 0.000
M25.77 Osteophyte (Ankle and foot)
0.712 0.288 0.000
M25.46 Effusion of joint (Lower leg)
0.712 0.288 0.000
M25.9 Joint disorder, unspecified
0.712 0.288 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.712 0.288 0.000
M25.3 Other instability of joint
0.712 0.288 0.000
M25.2 Flail joint
0.712 0.288 0.000
M25.1 Fistula of joint
0.712 0.288 0.000
M25.0 Haemarthrosis
0.712 0.288 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.711 0.289 0.000
M24 Other specific joint derangements
0.710 0.290 0.000
M75.9 Shoulder lesion, unspecified
0.710 0.290 0.000
M84 Disorders of continuity of bone
0.710 0.290 0.000
D04 Carcinoma in situ of skin
0.709 0.291 0.000
I42 Cardiomyopathy
0.709 0.291 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.708 0.292 0.000
I00-I02 Acute rheumatic fever
0.708 0.292 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.707 0.292 0.000
H31 Other disorders of choroid
0.707 0.292 0.000
H30 Chorioretinal inflammation
0.707 0.292 0.000
M75.3 Calcific tendinitis of shoulder
0.707 0.293 0.000
L03 Cellulitis
0.707 0.293 0.000
T79-T79 Certain early complications of trauma
0.707 0.293 0.000
I52 Other heart disorders in diseases classified elsewhere
0.704 0.295 0.000
I48 Atrial fibrillation and flutter
0.704 0.295 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.704 0.295 0.000
I41 Myocarditis in diseases classified elsewhere
0.704 0.295 0.000
I40 Acute myocarditis
0.704 0.295 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.704 0.295 0.000
I36 Nonrheumatic tricuspid valve disorders
0.704 0.295 0.000
I32 Pericarditis in diseases classified elsewhere
0.704 0.295 0.000
I30 Acute pericarditis
0.704 0.295 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.704 0.296 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.703 0.296 0.000
H35.9 Retinal disorder, unspecified
0.703 0.297 0.000
H35.7 Separation of retinal layers
0.703 0.297 0.000
H35.5 Hereditary retinal dystrophy
0.703 0.297 0.000
H35.2 Other proliferative retinopathy
0.703 0.297 0.000
H35.1 Retinopathy of prematurity
0.703 0.297 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.702 0.297 0.000
M20.3 Other deformity of hallux (acquired)
0.702 0.298 0.000
Y83.3 Surgical operation with formation of external stoma
0.701 0.299 0.000
I51.7 Cardiomegaly
0.701 0.299 0.000
M25.50 Pain in joint (Multiple sites)
0.701 0.299 0.000
M25.54 Pain in joint (Hand)
0.700 0.300 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.700 0.300 0.000
M50-M54 Other dorsopathies
0.700 0.300 0.000
C77.8 Lymph nodes of multiple regions
0.699 0.301 0.000
C45 Mesothelioma
0.698 0.302 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.697 0.303 0.000
M81.9 Osteoporosis, unspecified
0.696 0.304 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.695 0.305 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.694 0.306 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.693 0.306 0.000
I71 Aortic aneurysm and dissection
0.693 0.307 0.000
D72.8 Other specified disorders of white blood cells
0.693 0.307 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.692 0.308 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.692 0.308 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.692 0.308 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.692 0.308 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.691 0.309 0.000
D05 Carcinoma in situ of breast
0.690 0.310 0.000
M22.4 Chondromalacia patellae
0.689 0.311 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.688 0.312 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.688 0.312 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.688 0.312 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.688 0.312 0.000
I45.9 Conduction disorder, unspecified
0.686 0.314 0.000
I31 Other diseases of pericardium
0.685 0.314 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.685 0.315 0.000
C77.2 Intra-abdominal lymph nodes
0.685 0.315 0.000
I35.0 Aortic (valve) stenosis
0.685 0.315 0.000
M25.59 Pain in joint (Site unspecified)
0.684 0.315 0.000
M25.58 Pain in joint (Other)
0.684 0.315 0.000
M31 Other necrotising vasculopathies
0.684 0.316 0.000
H25 Senile cataract
0.683 0.317 0.000
H43-H45 Disorders of vitreous body and globe
0.683 0.317 0.000
C77.0 Lymph nodes of head, face and neck
0.681 0.319 0.000
D75 Other diseases of blood and blood-forming organs
0.680 0.319 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.679 0.321 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.679 0.321 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.678 0.321 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.678 0.322 0.000
T66-T78 Other and unspecified effects of external causes
0.677 0.323 0.000
I35.9 Aortic valve disorder, unspecified
0.677 0.323 0.000
I26 Pulmonary embolism
0.677 0.323 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.676 0.324 0.000
C50.9 Breast, unspecified
0.676 0.324 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.676 0.324 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.674 0.326 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.673 0.327 0.000
B49 Unspecified mycosis
0.673 0.327 0.000
C51-C58 Malignant neoplasms of female genital organs
0.671 0.329 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.670 0.330 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.670 0.330 0.000
T85.2 Mechanical complication of intraocular lens
0.670 0.330 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.670 0.330 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.670 0.330 0.000
G70-G73 Diseases of myoneural junction and muscle
0.670 0.330 0.000
L89 Decubitus ulcer
0.669 0.331 0.000
H34 Retinal vascular occlusions
0.669 0.331 0.000
I49.9 Cardiac arrhythmia, unspecified
0.668 0.332 0.000
I45.5 Other specified heart block
0.667 0.333 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.666 0.334 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.666 0.334 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.666 0.334 0.000
M77 Other enthesopathies
0.666 0.334 0.000
L85 Other epidermal thickening
0.664 0.336 0.000
C34.3 Lower lobe, bronchus or lung
0.663 0.337 0.000
E13 Other specified diabetes mellitus
0.662 0.338 0.000
E12 Malnutrition-related diabetes mellitus
0.662 0.338 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.661 0.339 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.661 0.339 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.661 0.339 0.000
C31 Malignant neoplasm of accessory sinuses
0.661 0.339 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.661 0.339 0.000
C37 Malignant neoplasm of thymus
0.661 0.339 0.000
C33 Malignant neoplasm of trachea
0.661 0.339 0.000
C77.1 Intrathoracic lymph nodes
0.661 0.339 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.660 0.340 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.659 0.341 0.000
B18 Chronic viral hepatitis
0.659 0.341 0.000
S79 Other and unspecified injuries of hip and thigh
0.658 0.342 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.657 0.343 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.657 0.343 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.656 0.344 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.656 0.344 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.656 0.344 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.656 0.344 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.656 0.344 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.656 0.344 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.656 0.344 0.000
T83.2 Mechanical complication of graft of urinary organ
0.656 0.344 0.000
I74 Arterial embolism and thrombosis
0.656 0.344 0.000
D50 Iron deficiency anaemia
0.655 0.344 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.655 0.345 0.000
J41 Simple and mucopurulent chronic bronchitis
0.655 0.345 0.000
J46 Status asthmaticus
0.655 0.345 0.000
E10.5 With peripheral circulatory complications
0.655 0.345 0.000
E78.0 Pure hypercholesterolaemia
0.655 0.345 0.000
I45.6 Preexcitation syndrome
0.654 0.346 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.653 0.347 0.000
C50.5 Lower-outer quadrant of breast
0.653 0.347 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.652 0.348 0.000
M15 Polyarthrosis
0.652 0.348 0.000
U80 Agent resistant to penicillin and related antibiotics
0.651 0.349 0.000
M17.1 Other primary gonarthrosis
0.651 0.349 0.000
M35 Other systemic involvement of connective tissue
0.650 0.350 0.000
B25-B34 Other viral diseases
0.650 0.350 0.000
H55 Nystagmus and other irregular eye movements
0.649 0.351 0.000
M23.4 Loose body in knee
0.649 0.351 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.649 0.351 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.649 0.351 0.000
C69 Malignant neoplasm of eye and adnexa
0.648 0.352 0.000
M76 Enthesopathies of lower limb, excluding foot
0.647 0.353 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.647 0.353 0.000
M71 Other bursopathies
0.647 0.353 0.000
E00-E07 Disorders of thyroid gland
0.647 0.353 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.647 0.353 0.000
H51 Other disorders of binocular movement
0.647 0.353 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.646 0.354 0.000
I07.1 Tricuspid insufficiency
0.646 0.354 0.000
B17 Other acute viral hepatitis
0.645 0.355 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.644 0.356 0.000
T51 Toxic effect of alcohol
0.644 0.356 0.000
Y40 Systemic antibiotics
0.644 0.356 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.643 0.357 0.000
I09 Other rheumatic heart diseases
0.643 0.357 0.000
I06 Rheumatic aortic valve diseases
0.643 0.357 0.000
I05 Rheumatic mitral valve diseases
0.643 0.357 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.642 0.358 0.000
M87 Osteonecrosis
0.641 0.359 0.000
D03 Melanoma in situ
0.641 0.359 0.000
L03.1 Cellulitis of other parts of limb
0.640 0.360 0.000
L84 Corns and callosities
0.640 0.360 0.000
J00-J06 Acute upper respiratory infections
0.639 0.361 0.000
C77.4 Inguinal and lower limb lymph nodes
0.638 0.361 0.000
E14.8 With unspecified complications
0.638 0.362 0.000
E14.7 With multiple complications
0.638 0.362 0.000
E14.6 With other specified complications
0.638 0.362 0.000
E14.5 With peripheral circulatory complications
0.638 0.362 0.000
E14.4 With neurological complications
0.638 0.362 0.000
E14.2 Withrenal complications
0.638 0.362 0.000
E14.1 With ketoacidosis
0.638 0.362 0.000
E14.0 With coma
0.638 0.362 0.000
J98.9 Respiratory disorder, unspecified
0.638 0.362 0.000
D51 Vitamin B12 deficiency anaemia
0.638 0.362 0.000
C07 Malignant neoplasm of parotid gland
0.637 0.362 0.000
M85 Other disorders of bone density and structure
0.636 0.364 0.000
M83 Adult osteomalacia
0.636 0.364 0.000
M82 Osteoporosis in diseases classified elsewhere
0.636 0.364 0.000
M25.74 Osteophyte (Hand)
0.636 0.364 0.000
I45.8 Other specified conduction disorders
0.635 0.364 0.000
I45.4 Nonspecific intraventricular block
0.635 0.364 0.000
I45.3 Trifascicular block
0.635 0.364 0.000
I45.2 Bifascicular block
0.635 0.364 0.000
I45.0 Right fascicular block
0.635 0.364 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.635 0.365 0.000
M25.79 Osteophyte (Site unspecified)
0.635 0.365 0.000
M25.73 Osteophyte (Forearm)
0.635 0.365 0.000
M25.72 Osteophyte (Upper arm)
0.635 0.365 0.000
M25.70 Osteophyte (Multiple sites)
0.635 0.365 0.000
Y84.9 Medical procedure, unspecified
0.634 0.366 0.000
Y84.7 Blood-sampling
0.634 0.366 0.000
Y84.5 Insertion of gastric or duodenal sound
0.634 0.366 0.000
Y84.4 Aspiration of fluid
0.634 0.366 0.000
Y84.3 Shock therapy
0.634 0.366 0.000
Y84.1 Kidney dialysis
0.634 0.366 0.000
H27 Other disorders of lens
0.633 0.367 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.633 0.367 0.000
C32.1 Supraglottis
0.632 0.368 0.000
M17.0 Primary gonarthrosis, bilateral
0.631 0.368 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.631 0.368 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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