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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72798117
log Bayes Factor = 5.28699
Chromosome 5   position 107,325,940  (GRCh37) Explore rs72798117 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M15-M19 Arthrosis
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.999 0.001 0.000
M17 Gonarthrosis [arthrosis of knee]
0.998 0.002 0.000
M17.1 Other primary gonarthrosis
0.995 0.005 0.000
M20-M25 Other joint disorders
0.987 0.013 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.984 0.016 0.000
E10.9 Without complications
0.979 0.021 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.971 0.029 0.000
M19 Other arthrosis
0.969 0.031 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.966 0.034 0.000
E11 Non-insulin-dependent diabetes mellitus
0.960 0.040 0.000
M80-M85 Disorders of bone density and structure
0.959 0.041 0.000
M17.0 Primary gonarthrosis, bilateral
0.954 0.046 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.948 0.052 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.944 0.056 0.000
W00-W19 Falls
0.940 0.060 0.000
M19.9 Arthrosis, unspecified
0.939 0.061 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.938 0.062 0.000
Chapter V Mental and behavioural disorders
0.932 0.068 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.926 0.074 0.000
M16 Coxarthrosis [arthrosis of hip]
0.924 0.076 0.000
E10.3 With ophthalmic complications
0.918 0.082 0.000
M19.94 Arthrosis, unspecified (Hand)
0.916 0.084 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.914 0.086 0.000
E50-E64 Other nutritional deficiencies
0.912 0.088 0.000
E10.5 With peripheral circulatory complications
0.911 0.089 0.000
M16.1 Other primary coxarthrosis
0.908 0.092 0.000
Y95 Nosocomial condition
0.907 0.093 0.000
M22 Disorders of patella
0.900 0.100 0.000
M25 Other joint disorders, not elsewhere classified
0.899 0.101 0.000
M35 Other systemic involvement of connective tissue
0.898 0.102 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.897 0.103 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.897 0.103 0.000
Y43 Primarily systemic agents
0.896 0.104 0.000
W19 Unspecified fall
0.895 0.105 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.893 0.107 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.885 0.115 0.000
M80 Osteoporosis with pathological fracture
0.881 0.119 0.000
E11.5 With peripheral circulatory complications
0.877 0.123 0.000
M25.4 Effusion of joint
0.876 0.124 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.871 0.129 0.000
E20-E35 Disorders of other endocrine glands
0.870 0.130 0.000
W19.9 Unspecified place
0.867 0.133 0.000
M25.46 Effusion of joint (Lower leg)
0.864 0.136 0.000
X41.9 Unspecified place
0.861 0.139 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.861 0.139 0.000
E10.1 With ketoacidosis
0.860 0.140 0.000
M24 Other specific joint derangements
0.856 0.144 0.000
S70-S79 Injuries to the hip and thigh
0.848 0.152 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.847 0.153 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.843 0.157 0.000
E53 Deficiency of other B group vitamins
0.840 0.160 0.000
S90-S99 Injuries to the ankle and foot
0.832 0.168 0.000
E11.4 With neurological complications
0.828 0.172 0.000
Chapter IX Diseases of the circulatory system
0.824 0.176 0.000
M22.4 Chondromalacia patellae
0.823 0.177 0.000
I30-I52 Other forms of heart disease
0.823 0.177 0.000
Y43.3 Other antineoplastic drugs
0.822 0.178 0.000
M35.3 Polymyalgia rheumatica
0.819 0.181 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.814 0.186 0.000
V40-V49 Car occupant injured in transport accident
0.812 0.188 0.000
S10-S19 Injuries to the neck
0.809 0.191 0.000
M23 Internal derangement of knee
0.808 0.192 0.000
S20-S29 Injuries to the thorax
0.806 0.194 0.000
E11.9 Without complications
0.806 0.194 0.000
M40-M43 Deforming dorsopathies
0.805 0.195 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.804 0.196 0.000
M05-M14 Inflammatory polyarthropathies
0.804 0.196 0.000
E16 Other disorders of pancreatic internal secretion
0.803 0.197 0.000
Y45.0 Opioids and related analgesics
0.803 0.197 0.000
M82 Osteoporosis in diseases classified elsewhere
0.803 0.197 0.000
V80-V89 Other land transport accidents
0.799 0.200 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.799 0.201 0.000
I51 Complications and ill-defined descriptions of heart disease
0.799 0.201 0.000
F60-F69 Disorders of adult personality and behaviour
0.798 0.201 0.000
Y46.2 Hydantoin derivatives
0.797 0.203 0.000
X60-X84 Intentional self-harm
0.794 0.206 0.000
X45 Accidental poisoning by and exposure to alcohol
0.792 0.208 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.791 0.209 0.000
E53.8 Deficiency of other specified B group vitamins
0.788 0.212 0.000
W50-W64 Exposure to animate mechanical forces
0.788 0.212 0.000
M15 Polyarthrosis
0.787 0.213 0.000
M60-M63 Disorders of muscles
0.786 0.214 0.000
I35 Nonrheumatic aortic valve disorders
0.784 0.216 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.783 0.217 0.000
M31 Other necrotising vasculopathies
0.783 0.217 0.000
E10.6 With other specified complications
0.778 0.222 0.000
E10.4 With neurological complications
0.776 0.224 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.776 0.224 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.776 0.224 0.000
M19.0 Primary arthrosis of other joints
0.775 0.225 0.000
I51.7 Cardiomegaly
0.775 0.225 0.000
T43.2 Other and unspecified antidepressants
0.774 0.226 0.000
Y45.1 Salicylates
0.770 0.230 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.769 0.231 0.000
M17.3 Other posttraumatic gonarthrosis
0.769 0.231 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.768 0.232 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.768 0.232 0.000
M00-M03 Infectious arthropathies
0.766 0.234 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.766 0.234 0.000
E13 Other specified diabetes mellitus
0.764 0.236 0.000
X50-X57 Overexertion, travel and privation
0.764 0.236 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.763 0.237 0.000
E10.2 With renal complications
0.760 0.240 0.000
M86-M90 Other osteopathies
0.759 0.241 0.000
E11.1 With ketoacidosis
0.757 0.243 0.000
M81 Osteoporosis without pathological fracture
0.756 0.244 0.000
Y44 Agents primarily affecting blood constituents
0.751 0.249 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.751 0.249 0.000
Chapter VI Diseases of the nervous system
0.751 0.249 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.748 0.252 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.747 0.253 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.746 0.254 0.000
W05 Fall involving wheelchair
0.745 0.255 0.000
E16.2 Hypoglycaemia, unspecified
0.744 0.256 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.743 0.257 0.000
I34 Nonrheumatic mitral valve disorders
0.742 0.258 0.000
S70 Superficial injury of hip and thigh
0.741 0.259 0.000
E11.2 With renal complications
0.741 0.259 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.740 0.260 0.000
M22.2 Patellofemoral disorders
0.739 0.261 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.738 0.262 0.000
Y46.4 Iminostilbenes
0.738 0.262 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.734 0.266 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.733 0.267 0.000
M16.3 Other dysplastic coxarthrosis
0.733 0.267 0.000
M35.1 Other overlap syndromes
0.732 0.267 0.000
M84 Disorders of continuity of bone
0.732 0.267 0.000
S71 Open wound of hip and thigh
0.732 0.268 0.000
W08 Fall involving other furniture
0.729 0.271 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.728 0.272 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.727 0.273 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.727 0.273 0.000
Q80-Q89 Other congenital malformations
0.727 0.273 0.000
E29 Testicular dysfunction
0.727 0.273 0.000
E40-E46 Malnutrition
0.727 0.273 0.000
W18 Other fall on same level
0.726 0.274 0.000
E65-E68 Obesity and other hyperalimentation
0.726 0.274 0.000
W20-W49 Exposure to inanimate mechanical forces
0.725 0.275 0.000
Y57 Other and unspecified drugs and medicaments
0.725 0.275 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.719 0.281 0.000
T42.0 Hydantoin derivatives
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
E10.8 With unspecified complications
0.716 0.284 0.000
E10.7 With multiple complications
0.716 0.284 0.000
E10.0 With coma
0.716 0.284 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.716 0.284 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.716 0.284 0.000
I33 Acute and subacute endocarditis
0.715 0.285 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.715 0.285 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.714 0.286 0.000
W11 Fall on and from ladder
0.714 0.286 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.712 0.288 0.000
E61 Deficiency of other nutrient elements
0.711 0.289 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.710 0.290 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.709 0.291 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.708 0.292 0.000
M33 Dermatopolymyositis
0.708 0.292 0.000
M32 Systemic lupus erythematosus
0.708 0.292 0.000
M30 Polyarteritis nodosa and related conditions
0.708 0.292 0.000
M19.98 Arthrosis, unspecified (Other)
0.706 0.294 0.000
Y59 Other and unspecified vaccines and biological substances
0.706 0.294 0.000
Y58 Bacterial vaccines
0.706 0.294 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.706 0.294 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.706 0.294 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.706 0.294 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.706 0.294 0.000
Y48 Anaesthetics and therapeutic gases
0.706 0.294 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.706 0.294 0.000
M65-M68 Disorders of synovium and tendon
0.704 0.296 0.000
V10-V19 Pedal cyclist injured in transport accident
0.704 0.296 0.000
F60 Specific personality disorders
0.703 0.297 0.000
M25.3 Other instability of joint
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.702 0.298 0.000
I34.0 Mitral (valve) insufficiency
0.701 0.299 0.000
W19.4 Street and highway
0.700 0.300 0.000
M05 Seropositive rheumatoid arthritis
0.697 0.302 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.697 0.303 0.000
M17.5 Other secondary gonarthrosis
0.697 0.303 0.000
E24 Cushing's syndrome
0.697 0.303 0.000
M43 Other deforming dorsopathies
0.696 0.304 0.000
T33-T35 Frostbite
0.696 0.304 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.696 0.304 0.000
T00-T07 Injuries involving multiple body regions
0.696 0.304 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.695 0.305 0.000
M19.8 Other specified arthrosis
0.695 0.305 0.000
M19.2 Other secondary arthrosis
0.695 0.305 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.695 0.305 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.694 0.305 0.000
G30-G32 Other degenerative diseases of the nervous system
0.694 0.306 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.692 0.307 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.692 0.307 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.692 0.307 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.692 0.307 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.692 0.307 0.000
T36 Poisoning by systemic antibiotics
0.692 0.307 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.691 0.309 0.000
M82.1 Osteoporosis in endocrine disorders
0.691 0.309 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.690 0.310 0.000
M81.4 Drug-induced osteoporosis
0.690 0.310 0.000
X20-X29 Contact with venomous animals and plants
0.689 0.311 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.689 0.311 0.000
E11.7 With multiple complications
0.688 0.312 0.000
M83 Adult osteomalacia
0.688 0.312 0.000
F30-F39 Mood [affective] disorders
0.685 0.315 0.000
E20 Hypoparathyroidism
0.684 0.315 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.684 0.315 0.000
F45 Somatoform disorders
0.684 0.316 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.682 0.318 0.000
M19.1 Posttraumatic arthrosis of other joints
0.681 0.318 0.000
E11.8 With unspecified complications
0.680 0.319 0.000
X45.0 Home
0.680 0.320 0.000
X48 Accidental poisoning by and exposure to pesticides
0.679 0.320 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.679 0.320 0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.679 0.320 0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.679 0.320 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.679 0.320 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.679 0.320 0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.679 0.320 0.000
V20-V29 Motorcycle rider injured in transport accident
0.679 0.321 0.000
M85 Other disorders of bone density and structure
0.678 0.322 0.000
M21 Other acquired deformities of limbs
0.678 0.322 0.000
W17 Other fall from one level to another
0.678 0.322 0.000
I95 Hypotension
0.677 0.322 0.000
S90 Superficial injury of ankle and foot
0.677 0.323 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.677 0.323 0.000
Y98 Lifestyle-related condition
0.677 0.323 0.000
Y97 Environmental-pollution-related condition
0.677 0.323 0.000
Y96 Work-related condition
0.677 0.323 0.000
Y43.4 Immunosuppressive agents
0.676 0.324 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.676 0.324 0.000
M23.4 Loose body in knee
0.676 0.324 0.000
F99-F99 Unspecified mental disorder
0.675 0.325 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.674 0.326 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.674 0.326 0.000
W15 Fall from cliff
0.674 0.326 0.000
W14 Fall from tree
0.674 0.326 0.000
W12 Fall on and from scaffolding
0.674 0.326 0.000
W09 Fall involving playground equipment
0.674 0.326 0.000
W04 Fall while being carried or supported by other persons
0.674 0.326 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.674 0.326 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.674 0.326 0.000
W00 Fall on same level involving ice and snow
0.674 0.326 0.000
M06 Other rheumatoid arthritis
0.673 0.327 0.000
T43.9 Psychotropic drug, unspecified
0.673 0.327 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.673 0.327 0.000
T43.6 Psychostimulants with abuse potential
0.673 0.327 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.673 0.327 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.673 0.327 0.000
Q23 Congenital malformations of aortic and mitral valves
0.673 0.327 0.000
W13 Fall from, out of or through building or structure
0.670 0.330 0.000
Q00-Q07 Congenital malformations of the nervous system
0.670 0.330 0.000
Chapter XXII Codes for special purposes
0.669 0.330 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.668 0.332 0.000
F70-F79 Mental retardation
0.668 0.332 0.000
I49 Other cardiac arrhythmias
0.667 0.333 0.000
E23 Hypofunction and other disorders of pituitary gland
0.665 0.335 0.000
M86 Osteomyelitis
0.665 0.335 0.000
E34 Other endocrine disorders
0.665 0.335 0.000
I95.9 Hypotension, unspecified
0.665 0.335 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.664 0.336 0.000
Q35-Q37 Cleft lip and cleft palate
0.664 0.336 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.664 0.336 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.664 0.336 0.000
E11.6 With other specified complications
0.663 0.337 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.662 0.338 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.662 0.338 0.000
T79-T79 Certain early complications of trauma
0.662 0.338 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.662 0.338 0.000
E11.0 With coma
0.661 0.338 0.000
Q60-Q64 Congenital malformations of the urinary system
0.661 0.339 0.000
M23.3 Other meniscus derangements
0.660 0.340 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.659 0.340 0.000
M34 Systemic sclerosis
0.658 0.342 0.000
G20-G26 Extrapyramidal and movement disorders
0.658 0.342 0.000
S91 Open wound of ankle and foot
0.657 0.343 0.000
S10 Superficial injury of neck
0.657 0.343 0.000
I35.9 Aortic valve disorder, unspecified
0.656 0.344 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.656 0.344 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.655 0.345 0.000
Y45.8 Other analgesics and antipyretics
0.655 0.345 0.000
Y45.5 4-Aminophenol derivatives
0.655 0.345 0.000
Y45.4 Antirheumatics
0.655 0.345 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.654 0.345 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.654 0.346 0.000
E63 Other nutritional deficiencies
0.654 0.346 0.000
E56 Other vitamin deficiencies
0.654 0.346 0.000
E51 Thiamine deficiency
0.654 0.346 0.000
E50 Vitamin A deficiency
0.654 0.346 0.000
E60 Dietary zinc deficiency
0.654 0.346 0.000
E59 Dietary selenium deficiency
0.654 0.346 0.000
E58 Dietary calcium deficiency
0.654 0.346 0.000
E54 Ascorbic acid deficiency
0.654 0.346 0.000
E52 Niacin deficiency [pellagra]
0.654 0.346 0.000
M24.5 Contracture of joint
0.653 0.347 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.653 0.347 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.651 0.349 0.000
T42.1 Iminostilbenes
0.651 0.349 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.649 0.351 0.000
S71.1 Open wound of thigh
0.649 0.351 0.000
M16.5 Other posttraumatic coxarthrosis
0.647 0.353 0.000
I35.0 Aortic (valve) stenosis
0.647 0.353 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.647 0.353 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.645 0.354 0.000
M22.1 Recurrent subluxation of patella
0.645 0.355 0.000
M22.9 Disorder of patella, unspecified
0.645 0.355 0.000
M22.3 Other derangements of patella
0.645 0.355 0.000
M22.0 Recurrent dislocation of patella
0.645 0.355 0.000
M25.2 Flail joint
0.644 0.356 0.000
M25.1 Fistula of joint
0.644 0.356 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.644 0.356 0.000
M35.8 Other specified systemic involvement of connective tissue
0.644 0.356 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.644 0.356 0.000
M35.5 Multifocal fibrosclerosis
0.644 0.356 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.644 0.356 0.000
M35.2 Behcet's disease
0.644 0.356 0.000
X41.0 Home
0.643 0.357 0.000
X41.8 Other specified place
0.643 0.357 0.000
X41.7 Farm
0.643 0.357 0.000
X41.6 Industrial and construction area
0.643 0.357 0.000
X41.5 Trade and service area
0.643 0.357 0.000
X41.4 Street and highway
0.643 0.357 0.000
X41.3 Sports and athletics area
0.643 0.357 0.000
X41.2 School, other institution and public administrative area
0.643 0.357 0.000
X41.1 Residential institution
0.643 0.357 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.643 0.357 0.000
Y46.8 Antispasticity drugs
0.643 0.357 0.000
Y46.7 Anti-Parkinsonism drugs
0.643 0.357 0.000
Y46.6 Other and unspecified antiepileptics
0.643 0.357 0.000
Y46.5 Valproic acid
0.643 0.357 0.000
Y46.3 Deoxybarbiturates
0.643 0.357 0.000
Y46.1 Oxazolidinediones
0.643 0.357 0.000
Y46.0 Succinimides
0.643 0.357 0.000
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident
0.643 0.357 0.000
S80-S89 Injuries to the knee and lower leg
0.643 0.357 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.642 0.358 0.000
Y43.9 Primarily systemic agent, unspecified
0.642 0.358 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.642 0.358 0.000
Y43.6 Enzymes, not elsewhere classified
0.642 0.358 0.000
Y43.5 Acidifying and alkalising agents
0.642 0.358 0.000
Y43.2 Antineoplastic natural products
0.642 0.358 0.000
Y43.1 Antineoplastic antimetabolites
0.642 0.358 0.000
Y43.0 Antiallergic and antiemetic drugs
0.642 0.358 0.000
W19.8 Other specified place
0.642 0.358 0.000
W19.5 Trade and service area
0.642 0.358 0.000
W19.0 Home
0.642 0.358 0.000
W19.7 Farm
0.642 0.358 0.000
W19.6 Industrial and construction area
0.642 0.358 0.000
W19.1 Residential institution
0.642 0.358 0.000
E21.0 Primary hyperparathyroidism
0.642 0.358 0.000
W06 Fall involving bed
0.642 0.358 0.000
I30 Acute pericarditis
0.641 0.358 0.000
M23.9 Internal derangement of knee, unspecified
0.639 0.361 0.000
I33.0 Acute and subacute infective endocarditis
0.638 0.362 0.000
T51 Toxic effect of alcohol
0.638 0.362 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.637 0.363 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.636 0.364 0.000
M14 Arthropathies in other diseases classified elsewhere
0.636 0.364 0.000
W55 Bitten or struck by other mammals
0.636 0.364 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.635 0.365 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.635 0.365 0.000
Y40 Systemic antibiotics
0.635 0.365 0.000
E15 Nondiabetic hypoglycaemic coma
0.635 0.365 0.000
M62 Other disorders of muscle
0.633 0.367 0.000
I36 Nonrheumatic tricuspid valve disorders
0.633 0.367 0.000
M80.8 Other osteoporosis with pathological fracture
0.632 0.368 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.632 0.368 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.632 0.368 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.632 0.368 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.632 0.368 0.000
I51.6 Cardiovascular disease, unspecified
0.631 0.369 0.000
S27 Injury of other and unspecified intrathoracic organs
0.631 0.369 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.629 0.371 0.000
M35.7 Hypermobility syndrome
0.629 0.371 0.000
M25.49 Effusion of joint (Site unspecified)
0.628 0.372 0.000
M25.48 Effusion of joint (Other)
0.628 0.372 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.628 0.372 0.000
M25.44 Effusion of joint (Hand)
0.628 0.372 0.000
M25.43 Effusion of joint (Forearm)
0.628 0.372 0.000
M25.42 Effusion of joint (Upper arm)
0.628 0.372 0.000
M25.41 Effusion of joint (Shoulder region)
0.628 0.372 0.000
M25.40 Effusion of joint (Multiple sites)
0.628 0.372 0.000
V48 Car occupant injured in noncollision transport accident
0.627 0.373 0.000
F45.8 Other somatoform disorders
0.627 0.373 0.000
Y53.4 Other laxatives
0.626 0.374 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.626 0.374 0.000
Q50-Q56 Congenital malformations of genital organs
0.626 0.374 0.000
S29 Other and unspecified injuries of thorax
0.626 0.374 0.000
S92 Fracture of foot, except ankle
0.626 0.374 0.000
F17.1 Harmful use
0.625 0.375 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.625 0.375 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.625 0.375 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.625 0.375 0.000
T42.3 Barbiturates
0.625 0.375 0.000
T42.2 Succinimides and oxazolidinediones
0.625 0.375 0.000
E29.1 Testicular hypofunction
0.624 0.376 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.624 0.376 0.000
E32 Diseases of thymus
0.624 0.376 0.000
E31 Polyglandular dysfunction
0.624 0.376 0.000
E30 Disorders of puberty, not elsewhere classified
0.624 0.376 0.000
E25 Adrenogenital disorders
0.624 0.376 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.623 0.377 0.000
W20 Struck by thrown, projected or falling object
0.622 0.377 0.000
F42 Obsessive-compulsive disorder
0.622 0.378 0.000
E55 Vitamin D deficiency
0.622 0.378 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.622 0.378 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.621 0.379 0.000
M25.0 Haemarthrosis
0.620 0.380 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.620 0.380 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.619 0.381 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.618 0.382 0.000
Y45.2 Propionic acid derivatives
0.617 0.382 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.617 0.383 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.617 0.383 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.617 0.383 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.617 0.383 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.617 0.383 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.617 0.383 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.617 0.383 0.000
T44.0 Anticholinesterase agents
0.617 0.383 0.000
S20 Superficial injury of thorax
0.617 0.383 0.000
S79 Other and unspecified injuries of hip and thigh
0.617 0.383 0.000
E26 Hyperaldosteronism
0.617 0.383 0.000
M40 Kyphosis and lordosis
0.617 0.383 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.616 0.384 0.000
F60.3 Emotionally unstable personality disorder
0.615 0.385 0.000
M24.9 Joint derangement, unspecified
0.614 0.386 0.000
M24.7 Protrusio acetabuli
0.614 0.386 0.000
M24.6 Ankylosis of joint
0.614 0.386 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.614 0.386 0.000
I49.0 Ventricular fibrillation and flutter
0.614 0.386 0.000
Q65 Congenital deformities of hip
0.613 0.387 0.000
W19.2 School, other institution and public administrative area
0.612 0.388 0.000
E22 Hyperfunction of pituitary gland
0.611 0.389 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.611 0.389 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.609 0.391 0.000
F23 Acute and transient psychotic disorders
0.609 0.391 0.000
I51.9 Heart disease, unspecified
0.609 0.391 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.609 0.391 0.000
I46 Cardiac arrest
0.608 0.392 0.000
Q27 Other congenital malformations of peripheral vascular system
0.608 0.392 0.000
S78 Traumatic amputation of hip and thigh
0.608 0.392 0.000
S77 Crushing injury of hip and thigh
0.608 0.392 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.608 0.392 0.000
S75 Injury of blood vessels at hip and thigh level
0.608 0.392 0.000
S74 Injury of nerves at hip and thigh level
0.608 0.392 0.000
I47 Paroxysmal tachycardia
0.608 0.392 0.000
I37 Pulmonary valve disorders
0.607 0.393 0.000
Q76 Congenital malformations of spine and bony thorax
0.606 0.394 0.000
O85-O92 Complications predominantly related to the puerperium
0.606 0.394 0.000
Q24 Other congenital malformations of heart
0.605 0.394 0.000
W05.0 Home
0.605 0.395 0.000
T40.6 Other and unspecified narcotics
0.605 0.395 0.000
M25.7 Osteophyte
0.604 0.396 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.604 0.396 0.000
Y77 Ophthalmic devices associated with adverse incidents
0.604 0.396 0.000
Q28 Other congenital malformations of circulatory system
0.604 0.396 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.604 0.396 0.000
M31.3 Wegener's granulomatosis
0.603 0.396 0.000
O16 Unspecified maternal hypertension
0.603 0.397 0.000
M24.1 Other articular cartilage disorders
0.603 0.397 0.000
S12 Fracture of neck
0.602 0.398 0.000
E53.9 Vitamin B deficiency, unspecified
0.602 0.398 0.000
E53.1 Pyridoxine deficiency
0.602 0.398 0.000
E53.0 Riboflavin deficiency
0.602 0.398 0.000
M18 Arthrosis of first carpometacarpal joint
0.602 0.398 0.000
M35.0 Sicca syndrome [Sjogren]
0.602 0.398 0.000
S99 Other and unspecified injuries of ankle and foot
0.601 0.398 0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.601 0.399 0.000
M16.0 Primary coxarthrosis, bilateral
0.601 0.399 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.600 0.399 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.600 0.400 0.000
M91-M94 Chondropathies
0.600 0.400 0.000
M86.9 Osteomyelitis, unspecified
0.599 0.401 0.000
M00 Pyogenic arthritis
0.598 0.402 0.000
M24.2 Disorder of ligament
0.597 0.403 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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