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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Diagnostic term associations

Hospitalization Episode Statistics (HES)

E10.0
With coma
Parent term
E10 Insulin-dependent diabetes mellitus
What are diagnostic terms?
Variant effects

Click on a variant to see its association results.

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
rs9273363 lBF = 489.584   Chr6 : 32,626,272
0.989 0.011 0.000
rs9273364 lBF = 475.788   Chr6 : 32,626,302
0.986 0.014 0.000
rs6927022 lBF = 550.507   Chr6 : 32,612,397
0.974 0.026 0.000
rs2523454 lBF = 206.037   Chr6 : 31,367,865
0.973 0.027 0.000
rs2251396 lBF = 222.188   Chr6 : 31,364,707
0.972 0.028 0.000
rs241408 lBF = 108.889   Chr6 : 32,862,711
0.000 0.028 0.972
rs2523451 lBF = 189.434   Chr6 : 31,369,151
0.972 0.028 0.000
rs3129871 lBF = 356.615   Chr6 : 32,406,342
0.000 0.029 0.971
rs154978 lBF = 112.909   Chr6 : 32,899,296
0.000 0.029 0.971
rs3135335 lBF = 304.942   Chr6 : 32,401,845
0.000 0.031 0.969
rs3135395 lBF = 306.183   Chr6 : 32,405,192
0.000 0.031 0.969
rs984778 lBF = 300.859   Chr6 : 32,400,088
0.000 0.032 0.968
rs11077149 lBF = 5.70606   Chr16 : 7,264,782
0.968 0.032 0.000
rs3135338 lBF = 297.666   Chr6 : 32,401,217
0.000 0.032 0.968
rs2395166 lBF = 291.927   Chr6 : 32,388,275
0.000 0.032 0.968
rs2018501 lBF = 108.223   Chr6 : 32,856,208
0.000 0.033 0.967
rs9273339 lBF = 437.281   Chr6 : 32,623,430
0.000 0.035 0.965
rs9273373 lBF = 453.011   Chr6 : 32,626,601
0.965 0.035 0.000
rs9273088 lBF = 442.306   Chr6 : 32,612,488
0.000 0.035 0.965
rs17843619 lBF = 439.369   Chr6 : 32,620,775
0.000 0.035 0.965
rs9273215 lBF = 440.214   Chr6 : 32,613,712
0.000 0.035 0.965
rs9272346 lBF = 453.316   Chr6 : 32,604,372
0.965 0.035 0.000
rs1063355 lBF = 441.898   Chr6 : 32,627,714
0.000 0.035 0.965
rs17612576 lBF = 440.731   Chr6 : 32,615,458
0.000 0.036 0.964
rs3129923 lBF = 214.888   Chr6 : 32,333,195
0.000 0.036 0.964
rs1265762 lBF = 210.925   Chr6 : 32,321,115
0.000 0.036 0.964
rs9274552 lBF = 439.186   Chr6 : 32,634,838
0.000 0.036 0.964
rs154988 lBF = 122.937   Chr6 : 32,877,266
0.000 0.036 0.964
rs2187688 lBF = 120.374   Chr6 : 32,872,001
0.000 0.037 0.963
rs241458 lBF = 122.511   Chr6 : 32,888,566
0.000 0.037 0.963
rs154989 lBF = 122.33   Chr6 : 32,877,173
0.000 0.037 0.963
rs4348357 lBF = 187.91   Chr6 : 32,291,359
0.000 0.037 0.963
rs17843606 lBF = 435.465   Chr6 : 32,620,399
0.000 0.037 0.963
Affx-28496566 lBF = 410.258   Chr6 : 32,625,869
0.000 0.037 0.963
rs3828790 lBF = 425.616   Chr6 : 32,635,809
0.000 0.038 0.962
Affx-37072023 lBF = 455.451   Chr6 : 32,612,430
0.000 0.038 0.962
rs1046089 lBF = 282.881   Chr6 : 31,602,967
0.962 0.038 0.000
rs4279480 lBF = 196.624   Chr6 : 32,290,927
0.000 0.038 0.962
rs926070 lBF = 194.58   Chr6 : 32,257,566
0.000 0.038 0.962
rs805303 lBF = 277.164   Chr6 : 31,616,366
0.961 0.039 0.000
rs805301 lBF = 275.726   Chr6 : 31,618,121
0.961 0.039 0.000
rs9271348 lBF = 305.289   Chr6 : 32,583,742
0.961 0.039 0.000
rs2273017 lBF = 201.258   Chr6 : 32,337,630
0.000 0.039 0.961
rs2242659 lBF = 276.776   Chr6 : 31,601,513
0.960 0.040 0.000
rs3129867 lBF = 289.989   Chr6 : 32,404,220
0.000 0.040 0.960
rs805257 lBF = 274.411   Chr6 : 31,634,193
0.960 0.040 0.000
rs1265758 lBF = 194.604   Chr6 : 32,323,529
0.000 0.042 0.958
rs2471980 lBF = 301.907   Chr6 : 31,800,868
0.958 0.042 0.000
rs2395150 lBF = 194.768   Chr6 : 32,326,045
0.000 0.042 0.958
rs3129908 lBF = 198.273   Chr6 : 32,325,707
0.000 0.042 0.958
rs2763979 lBF = 290.128   Chr6 : 31,794,592
0.958 0.042 0.000
rs3101942 lBF = 137.833   Chr6 : 32,870,057
0.000 0.042 0.958
rs2071540 lBF = 75.202   Chr6 : 32,812,916
0.000 0.042 0.958
rs9276916 lBF = 137.921   Chr6 : 32,866,095
0.000 0.043 0.957
rs805305 lBF = 268.824   Chr6 : 31,697,387
0.957 0.043 0.000
rs805304 lBF = 274.178   Chr6 : 31,698,088
0.957 0.043 0.000
rs241405 lBF = 120.324   Chr6 : 32,865,798
0.000 0.043 0.957
rs805294 lBF = 275.309   Chr6 : 31,688,217
0.956 0.044 0.000
rs707916 lBF = 270.513   Chr6 : 31,697,558
0.956 0.044 0.000
Affx-28456540 lBF = 145.563   Chr6 : 31,412,961
0.000 0.046 0.954
rs9273349 lBF = 389.4   Chr6 : 32,625,869
0.953 0.047 0.000
rs9268515 lBF = 390.149   Chr6 : 32,379,295
0.952 0.048 0.000
rs6910071 lBF = 365.296   Chr6 : 32,282,854
0.952 0.048 0.000
rs9268145 lBF = 359.052   Chr6 : 32,257,284
0.952 0.048 0.000
rs28361060 lBF = 366.643   Chr6 : 32,303,848
0.952 0.048 0.000
rs9268362 lBF = 364.835   Chr6 : 32,333,341
0.951 0.049 0.000
rs3763312 lBF = 361.447   Chr6 : 32,376,348
0.951 0.049 0.000
rs9275319 lBF = 298.483   Chr6 : 32,666,295
0.950 0.050 0.000
rs9273489 lBF = 297.232   Chr6 : 32,628,189
0.950 0.050 0.000
rs3763309 lBF = 364.621   Chr6 : 32,375,973
0.950 0.050 0.000
rs3793127 lBF = 363.437   Chr6 : 32,371,915
0.950 0.050 0.000
rs241398 lBF = 109.754   Chr6 : 32,875,450
0.950 0.050 0.000
rs241404 lBF = 109.445   Chr6 : 32,865,997
0.949 0.051 0.000
rs241402 lBF = 111.025   Chr6 : 32,869,045
0.949 0.051 0.000
rs9275334 lBF = 329.259   Chr6 : 32,667,107
0.949 0.051 0.000
rs3998159 lBF = 336.331   Chr6 : 32,682,019
0.948 0.052 0.000
rs2073044 lBF = 297.22   Chr6 : 32,338,986
0.948 0.052 0.000
rs3134996 lBF = 399.72   Chr6 : 32,636,866
0.000 0.052 0.948
rs9275326 lBF = 348.679   Chr6 : 32,666,660
0.947 0.053 0.000
rs9275312 lBF = 293.704   Chr6 : 32,665,728
0.947 0.053 0.000
rs7454108 lBF = 345.123   Chr6 : 32,681,483
0.947 0.053 0.000
rs9275532 lBF = 333.93   Chr6 : 32,675,634
0.947 0.053 0.000
rs9275356 lBF = 346.337   Chr6 : 32,667,850
0.947 0.053 0.000
rs9275184 lBF = 339.999   Chr6 : 32,654,714
0.946 0.054 0.000
rs3129882 lBF = 286.214   Chr6 : 32,409,530
0.000 0.054 0.946
Affx-28502500 lBF = 331.394   Chr6 : 32,682,137
0.946 0.054 0.000
rs3763349 lBF = 75.327   Chr6 : 32,808,232
0.000 0.054 0.946
rs9273401 lBF = 339.214   Chr6 : 32,627,129
0.945 0.055 0.000
rs707929 lBF = 287.181   Chr6 : 31,742,067
0.944 0.056 0.000
rs910049 lBF = 214.799   Chr6 : 32,315,727
0.000 0.056 0.944
rs2253907 lBF = 110.95   Chr6 : 31,336,870
0.000 0.056 0.944
rs3129886 lBF = 272.418   Chr6 : 32,410,576
0.000 0.056 0.944
rs3129883 lBF = 273.029   Chr6 : 32,410,137
0.000 0.056 0.944
rs241425 lBF = 142.682   Chr6 : 32,804,909
0.000 0.057 0.943
rs2523484 lBF = 83.0266   Chr6 : 31,353,639
0.000 0.057 0.943
rs3132131 lBF = 95.8324   Chr6 : 32,899,485
0.000 0.057 0.943
rs9275338 lBF = 287.168   Chr6 : 32,667,343
0.943 0.057 0.000
rs3129931 lBF = 217.166   Chr6 : 32,335,516
0.000 0.058 0.942
rs3752430 lBF = 79.6372   Chr6 : 32,832,667
0.000 0.058 0.942
rs707928 lBF = 282.972   Chr6 : 31,742,590
0.942 0.058 0.000
rs3957110 lBF = 108.138   Chr6 : 31,344,348
0.000 0.058 0.942
rs3132959 lBF = 218.555   Chr6 : 32,298,942
0.000 0.058 0.942
rs3117138 lBF = 217.565   Chr6 : 32,306,970
0.000 0.058 0.942
rs3129941 lBF = 218.3   Chr6 : 32,337,686
0.000 0.058 0.942
rs3117111 lBF = 217.05   Chr6 : 32,338,400
0.000 0.058 0.942
rs2894249 lBF = 216.976   Chr6 : 32,325,835
0.000 0.058 0.942
rs3129932 lBF = 217.142   Chr6 : 32,336,127
0.000 0.058 0.942
rs3132958 lBF = 219.016   Chr6 : 32,297,901
0.000 0.058 0.942
rs3117113 lBF = 216.453   Chr6 : 32,325,292
0.000 0.058 0.942
rs2395004 lBF = 140.498   Chr6 : 31,412,513
0.942 0.058 0.000
rs7741091 lBF = 119.854   Chr6 : 31,352,631
0.000 0.059 0.941
rs3129904 lBF = 212.446   Chr6 : 32,310,396
0.000 0.059 0.941
rs9271414 lBF = 291.31   Chr6 : 32,587,782
0.000 0.059 0.940
rs11244 lBF = 255.169   Chr6 : 32,780,724
0.940 0.060 0.000
rs6904320 lBF = 212.719   Chr6 : 32,312,082
0.000 0.060 0.940
rs241414 lBF = 104.656   Chr6 : 32,857,801
0.939 0.061 0.000
rs241413 lBF = 104.732   Chr6 : 32,859,000
0.939 0.061 0.000
rs2523534 lBF = 117.305   Chr6 : 31,336,349
0.000 0.061 0.939
rs689 lBF = 37.1324   Chr11 : 2,182,224
0.939 0.061 0.000
rs2239701 lBF = 159.351   Chr6 : 32,805,049
0.938 0.062 0.000
rs3129907 lBF = 216.31   Chr6 : 32,323,745
0.000 0.062 0.938
rs2256175 lBF = 74.2527   Chr6 : 31,380,449
0.000 0.063 0.937
rs6931277 lBF = 515.908   Chr6 : 32,583,357
0.937 0.063 0.000
rs660895 lBF = 476.437   Chr6 : 32,577,380
0.937 0.063 0.000
rs521539 lBF = 478.456   Chr6 : 32,581,973
0.937 0.063 0.000
rs2156875 lBF = 144.18   Chr6 : 31,317,347
0.000 0.064 0.936
rs5025315 lBF = 109.014   Chr6 : 31,343,604
0.000 0.064 0.936
rs3132943 lBF = 217.382   Chr6 : 32,308,465
0.000 0.065 0.935
rs2523638 lBF = 102.446   Chr6 : 31,344,273
0.000 0.065 0.935
rs3819720 lBF = 246.694   Chr6 : 32,804,570
0.935 0.065 0.000
rs77501456 lBF = 260.985   Chr6 : 32,523,627
0.000 0.066 0.934
rs11756897 lBF = 57.786   Chr6 : 32,899,139
0.934 0.066 0.000
rs9266774 lBF = 27.7177   Chr6 : 31,352,880
0.934 0.066 0.000
rs9266722 lBF = 28.5298   Chr6 : 31,349,922
0.934 0.066 0.000
rs532965 lBF = 522.853   Chr6 : 32,577,973
0.934 0.066 0.000
rs3104413 lBF = 510.724   Chr6 : 32,582,650
0.933 0.067 0.000
rs3828840 lBF = 272.834   Chr6 : 32,520,907
0.933 0.067 0.000
rs2844514 lBF = 73.5839   Chr6 : 31,380,340
0.000 0.067 0.933
rs3129720 lBF = 342.091   Chr6 : 32,663,631
0.933 0.067 0.000
rs9276726 lBF = 191.154   Chr6 : 32,763,888
0.932 0.068 0.000
rs2507985 lBF = 108.149   Chr6 : 31,343,100
0.000 0.068 0.932
rs72845730 lBF = 263.988   Chr6 : 32,526,731
0.000 0.068 0.932
rs5006724 lBF = 108.151   Chr6 : 31,337,850
0.000 0.068 0.932
rs2844513 lBF = 72.258   Chr6 : 31,388,214
0.000 0.069 0.931
rs3763365 lBF = 87.8968   Chr6 : 32,807,453
0.931 0.069 0.000
rs2844555 lBF = 95.7037   Chr6 : 31,341,379
0.000 0.069 0.931
rs9273502 lBF = 239.503   Chr6 : 32,628,389
0.931 0.069 0.000
rs9272449 lBF = 449.415   Chr6 : 32,605,451
0.931 0.069 0.000
rs3135344 lBF = 280.03   Chr6 : 32,395,036
0.000 0.069 0.931
rs6899857 lBF = 178.897   Chr6 : 32,770,482
0.930 0.070 0.000
rs9275599 lBF = 314.243   Chr6 : 32,682,429
0.930 0.070 0.000
rs2395163 lBF = 377.046   Chr6 : 32,387,809
0.930 0.070 0.000
rs28746867 lBF = 230.246   Chr6 : 32,635,293
0.929 0.071 0.000
rs3132944 lBF = 208.472   Chr6 : 32,307,446
0.000 0.071 0.929
rs9271209 lBF = 247.836   Chr6 : 32,579,035
0.000 0.071 0.929
rs9271117 lBF = 255.979   Chr6 : 32,576,795
0.000 0.071 0.929
rs2263323 lBF = 51.4038   Chr6 : 31,401,466
0.929 0.071 0.000
rs9270965 lBF = 191.046   Chr6 : 32,573,471
0.929 0.071 0.000
rs34250758 lBF = 518.249   Chr6 : 32,607,376
0.928 0.072 0.000
rs9270908 lBF = 254.18   Chr6 : 32,572,148
0.000 0.072 0.928
rs9271060 lBF = 261.575   Chr6 : 32,575,513
0.928 0.072 0.000
rs9271192 lBF = 261.325   Chr6 : 32,578,530
0.928 0.072 0.000
rs9271100 lBF = 261.675   Chr6 : 32,576,478
0.928 0.072 0.000
rs3763288 lBF = 52.2845   Chr6 : 31,370,367
0.928 0.072 0.000
rs2524279 lBF = 47.995   Chr6 : 31,392,906
0.928 0.072 0.000
rs9270227 lBF = 253.321   Chr6 : 32,556,699
0.000 0.072 0.928
rs2596466 lBF = 50.0976   Chr6 : 31,405,617
0.928 0.072 0.000
rs2523684 lBF = 49.8794   Chr6 : 31,426,399
0.928 0.072 0.000
rs2524280 lBF = 49.9065   Chr6 : 31,416,990
0.928 0.072 0.000
rs9269861 lBF = 251.556   Chr6 : 32,550,501
0.000 0.072 0.928
rs28724252 lBF = 242.458   Chr6 : 32,629,549
0.927 0.073 0.000
rs3957146 lBF = 341.478   Chr6 : 32,681,530
0.927 0.073 0.000
Affx-28498032 lBF = 239.951   Chr6 : 32,631,570
0.927 0.073 0.000
rs5006725 lBF = 104.879   Chr6 : 31,337,872
0.000 0.073 0.927
rs9378249 lBF = 48.8892   Chr6 : 31,327,701
0.927 0.073 0.000
Affx-28453750 lBF = 103.934   Chr6 : 31,340,491
0.000 0.074 0.926
rs3129716 lBF = 409.333   Chr6 : 32,657,436
0.926 0.074 0.000
rs9268614 lBF = 379.521   Chr6 : 32,402,778
0.926 0.074 0.000
rs2647044 lBF = 409.49   Chr6 : 32,667,910
0.926 0.074 0.000
rs6916742 lBF = 323.838   Chr6 : 32,453,191
0.926 0.074 0.000
rs2854275 lBF = 405.249   Chr6 : 32,628,428
0.926 0.074 0.000
rs9268514 lBF = 207.251   Chr6 : 32,378,945
0.926 0.074 0.000
rs9268401 lBF = 190.875   Chr6 : 32,341,318
0.925 0.075 0.000
rs9275399 lBF = 243.294   Chr6 : 32,669,712
0.925 0.075 0.000
rs1480382 lBF = 143.186   Chr6 : 32,740,895
0.925 0.075 0.000
rs2524084 lBF = 215.728   Chr6 : 31,241,639
0.925 0.075 0.000
rs2856674 lBF = 406.303   Chr6 : 32,659,645
0.925 0.075 0.000
rs9276644 lBF = 145.002   Chr6 : 32,745,043
0.925 0.075 0.000
rs1150755 lBF = 380.176   Chr6 : 32,038,550
0.925 0.075 0.000
rs1150754 lBF = 379.048   Chr6 : 32,050,758
0.925 0.075 0.000
rs1150758 lBF = 380.161   Chr6 : 32,028,149
0.924 0.076 0.000
rs9272729 lBF = 402.73   Chr6 : 32,609,594
0.924 0.076 0.000
rs3131875 lBF = 44.7656   Chr6 : 29,666,111
0.000 0.076 0.924
rs7383606 lBF = 179.21   Chr6 : 32,766,593
0.924 0.076 0.000
rs2523708 lBF = 235.06   Chr6 : 31,451,279
0.923 0.077 0.000
rs2022534 lBF = 235.731   Chr6 : 32,307,137
0.923 0.077 0.000
rs2516415 lBF = 215.848   Chr6 : 31,459,742
0.923 0.077 0.000
rs3948793 lBF = 140.872   Chr6 : 32,759,448
0.923 0.077 0.000
rs3021302 lBF = 364.737   Chr6 : 32,623,150
0.922 0.078 0.000
rs2523700 lBF = 234.948   Chr6 : 31,453,029
0.922 0.078 0.000
rs707938 lBF = 236.606   Chr6 : 31,729,359
0.922 0.078 0.000
rs7382649 lBF = 178.914   Chr6 : 32,776,087
0.922 0.078 0.000
rs9380290 lBF = 237.099   Chr6 : 32,301,452
0.922 0.078 0.000
rs6912002 lBF = 178.474   Chr6 : 32,765,268
0.922 0.078 0.000
rs12524487 lBF = 43.9884   Chr6 : 31,354,238
0.922 0.078 0.000
rs7381376 lBF = 178.508   Chr6 : 32,767,673
0.922 0.078 0.000
rs1383261 lBF = 177.515   Chr6 : 32,765,451
0.922 0.078 0.000
rs9275407 lBF = 237.54   Chr6 : 32,670,037
0.922 0.078 0.000
rs7382714 lBF = 181.162   Chr6 : 32,767,496
0.922 0.078 0.000
rs2844532 lBF = 23.6794   Chr6 : 31,351,175
0.922 0.078 0.000
rs9276734 lBF = 178.832   Chr6 : 32,766,854
0.922 0.078 0.000
rs7756262 lBF = 257.891   Chr6 : 32,398,675
0.922 0.078 0.000
rs2076540 lBF = 236.393   Chr6 : 32,317,276
0.921 0.079 0.000
rs9275388 lBF = 241.462   Chr6 : 32,669,084
0.921 0.079 0.000
rs504203 lBF = 225.114   Chr6 : 32,294,843
0.921 0.079 0.000
rs9275375 lBF = 239.212   Chr6 : 32,668,632
0.921 0.079 0.000
rs9275390 lBF = 241.559   Chr6 : 32,669,156
0.921 0.079 0.000
rs9275418 lBF = 240.862   Chr6 : 32,670,244
0.921 0.079 0.000
rs3115667 lBF = 170.945   Chr6 : 31,643,399
0.000 0.079 0.921
rs9275406 lBF = 241.305   Chr6 : 32,669,955
0.921 0.079 0.000
rs9275440 lBF = 239.189   Chr6 : 32,671,596
0.921 0.079 0.000
rs2272593 lBF = 170.088   Chr6 : 31,601,344
0.000 0.079 0.921
rs1046080 lBF = 173.349   Chr6 : 31,595,882
0.000 0.079 0.921
rs9268657 lBF = 267.525   Chr6 : 32,409,656
0.920 0.080 0.000
rs1264372 lBF = 207.802   Chr6 : 30,769,726
0.920 0.080 0.000
rs2187818 lBF = 269.42   Chr6 : 32,395,568
0.920 0.080 0.000
rs2857597 lBF = 169.25   Chr6 : 31,585,000
0.000 0.080 0.920
rs2844529 lBF = 82.6347   Chr6 : 31,353,593
0.000 0.080 0.920
rs2428486 lBF = 82.6568   Chr6 : 31,354,104
0.000 0.080 0.920
rs477005 lBF = 241.632   Chr6 : 32,270,500
0.920 0.080 0.000
rs2050188 lBF = 209.683   Chr6 : 32,339,897
0.000 0.080 0.920
rs2428475 lBF = 82.1548   Chr6 : 31,366,622
0.000 0.080 0.920
Affx-28454788 lBF = 82.9195   Chr6 : 31,361,710
0.000 0.080 0.920
rs2857218 lBF = 123.609   Chr6 : 32,855,340
0.920 0.080 0.000
rs546857 lBF = 242.049   Chr6 : 32,289,240
0.920 0.080 0.000
rs9275595 lBF = 259.515   Chr6 : 32,681,355
0.919 0.081 0.000
rs2523467 lBF = 82.8014   Chr6 : 31,362,930
0.000 0.081 0.919
rs17574546 lBF = 13.6695   Chr15 : 38,902,476
0.919 0.081 0.000
rs3130617 lBF = 167.756   Chr6 : 31,627,523
0.000 0.081 0.919
rs2523452 lBF = 81.6495   Chr6 : 31,368,540
0.000 0.081 0.919
rs560505 lBF = 241.751   Chr6 : 32,261,771
0.919 0.081 0.000
rs3819715 lBF = 49.155   Chr6 : 32,804,219
0.000 0.081 0.919
rs9268528 lBF = 257.05   Chr6 : 32,383,108
0.919 0.081 0.000
rs7171171 lBF = 15.3328   Chr15 : 38,907,041
0.919 0.081 0.000
rs1475865 lBF = 169.543   Chr6 : 31,657,413
0.000 0.081 0.919
rs2596542 lBF = 80.8861   Chr6 : 31,366,595
0.000 0.081 0.919
rs1130399 lBF = 228.586   Chr6 : 32,629,755
0.918 0.082 0.000
rs2248459 lBF = 243.979   Chr6 : 31,446,710
0.918 0.082 0.000
rs9269819 lBF = 255.668   Chr6 : 32,549,782
0.000 0.082 0.918
rs9268645 lBF = 267.026   Chr6 : 32,408,527
0.918 0.082 0.000
rs16967103 lBF = 14.2899   Chr15 : 38,899,190
0.918 0.082 0.000
rs9380254 lBF = 46.9536   Chr6 : 31,378,335
0.918 0.082 0.000
rs9276820 lBF = 75.3736   Chr6 : 32,829,276
0.918 0.082 0.000
rs9276810 lBF = 113.26   Chr6 : 32,810,443
0.918 0.082 0.000
rs9268589 lBF = 268.355   Chr6 : 32,398,202
0.918 0.082 0.000
rs2071552 lBF = 93.2508   Chr6 : 32,806,461
0.918 0.082 0.000
rs3763346 lBF = 75.9625   Chr6 : 32,823,257
0.918 0.082 0.000
rs9271367 lBF = 258.737   Chr6 : 32,586,908
0.000 0.083 0.917
rs28366130 lBF = 82.5897   Chr6 : 31,363,805
0.000 0.083 0.917
rs9276825 lBF = 76.1735   Chr6 : 32,829,714
0.917 0.083 0.000
rs7773756 lBF = 268.297   Chr6 : 32,402,464
0.917 0.083 0.000
rs2071534 lBF = 74.4918   Chr6 : 32,824,318
0.917 0.083 0.000
rs2516424 lBF = 237.207   Chr6 : 31,448,315
0.917 0.083 0.000
rs434841 lBF = 249.848   Chr6 : 32,191,041
0.917 0.083 0.000
rs761187 lBF = 241.193   Chr6 : 32,318,036
0.917 0.083 0.000
rs2071476 lBF = 75.0235   Chr6 : 32,825,379
0.917 0.083 0.000
rs2243429 lBF = 238.954   Chr6 : 31,446,820
0.916 0.084 0.000
rs1146187 lBF = 37.7682   Chr1 : 114,212,571
0.916 0.084 0.000
rs2844502 lBF = 237.343   Chr6 : 31,445,216
0.916 0.084 0.000
rs2248613 lBF = 238.537   Chr6 : 31,448,432
0.916 0.084 0.000
rs2395488 lBF = 236.699   Chr6 : 31,445,909
0.916 0.084 0.000
rs3117098 lBF = 180.768   Chr6 : 32,358,513
0.000 0.084 0.916
rs2248617 lBF = 240.029   Chr6 : 31,448,533
0.916 0.084 0.000
rs3129948 lBF = 179.013   Chr6 : 32,354,644
0.000 0.084 0.916
rs3129954 lBF = 177.83   Chr6 : 32,365,580
0.000 0.084 0.916
rs1043618 lBF = 248.587   Chr6 : 31,783,507
0.916 0.084 0.000
rs3129961 lBF = 181.164   Chr6 : 32,378,940
0.000 0.084 0.916
rs3129952 lBF = 176.543   Chr6 : 32,359,763
0.000 0.084 0.916
rs9393691 lBF = 48.116   Chr6 : 26,272,829
0.000 0.084 0.916
rs9501589 lBF = 107.041   Chr6 : 31,364,383
0.000 0.084 0.916
rs4959096 lBF = 232.471   Chr6 : 32,314,676
0.915 0.084 0.000
rs2516491 lBF = 288.589   Chr6 : 31,485,101
0.915 0.085 0.000
rs14004 lBF = 260.821   Chr6 : 32,407,709
0.915 0.085 0.000
rs9268542 lBF = 254.807   Chr6 : 32,384,721
0.915 0.085 0.000
Affx-28475675 lBF = 305.306   Chr6 : 32,429,594
0.000 0.085 0.915
rs9275555 lBF = 255.458   Chr6 : 32,677,088
0.915 0.085 0.000
rs9268556 lBF = 255.394   Chr6 : 32,386,964
0.915 0.085 0.000
rs9275580 lBF = 252.588   Chr6 : 32,679,462
0.915 0.085 0.000
rs10774624 lBF = 108.174   Chr12 : 111,833,788
0.000 0.085 0.915
rs1555117 lBF = 234.559   Chr6 : 32,311,148
0.914 0.086 0.000
rs539703 lBF = 233.093   Chr6 : 32,288,462
0.914 0.086 0.000
rs1362089 lBF = 65.377   Chr6 : 30,209,802
0.914 0.086 0.000
rs9268285 lBF = 233.331   Chr6 : 32,315,557
0.914 0.086 0.000
rs9273011 lBF = 165.34   Chr6 : 32,611,611
0.914 0.086 0.000
rs5026743 lBF = 300.008   Chr6 : 32,439,964
0.000 0.086 0.914
rs4959025 lBF = 232.327   Chr6 : 32,313,143
0.914 0.086 0.000
rs241456 lBF = 114.422   Chr6 : 32,795,965
0.000 0.086 0.914
rs926591 lBF = 232.583   Chr6 : 32,305,690
0.914 0.086 0.000
rs9268615 lBF = 268.224   Chr6 : 32,402,889
0.914 0.086 0.000
rs9268384 lBF = 235.249   Chr6 : 32,336,586
0.914 0.086 0.000
rs552339 lBF = 234.514   Chr6 : 32,292,715
0.914 0.086 0.000
rs9405090 lBF = 232.861   Chr6 : 32,298,372
0.914 0.086 0.000
rs9268403 lBF = 206.094   Chr6 : 32,341,473
0.914 0.086 0.000
rs4959094 lBF = 233.503   Chr6 : 32,313,136
0.914 0.086 0.000
rs4959026 lBF = 232.702   Chr6 : 32,313,461
0.914 0.086 0.000
rs4713518 lBF = 231.079   Chr6 : 32,257,337
0.913 0.086 0.000
rs2143465 lBF = 235.869   Chr6 : 32,309,352
0.913 0.087 0.000
rs544358 lBF = 234.727   Chr6 : 32,273,158
0.913 0.087 0.000
rs9268132 lBF = 234.314   Chr6 : 32,254,654
0.913 0.087 0.000
rs4947350 lBF = 137.219   Chr6 : 32,767,620
0.913 0.087 0.000
rs1474728 lBF = 233.932   Chr6 : 32,302,067
0.913 0.087 0.000
rs4959093 lBF = 233.902   Chr6 : 32,313,097
0.913 0.087 0.000
rs3763316 lBF = 205.685   Chr6 : 32,376,746
0.913 0.087 0.000
rs10807100 lBF = 233.846   Chr6 : 32,303,068
0.913 0.087 0.000
rs9268284 lBF = 233.757   Chr6 : 32,315,216
0.913 0.087 0.000
rs6930616 lBF = 48.5109   Chr6 : 26,331,969
0.000 0.087 0.913
rs1033500 lBF = 235.443   Chr6 : 32,307,382
0.913 0.087 0.000
rs2073046 lBF = 234.117   Chr6 : 32,336,074
0.913 0.087 0.000
rs9268877 lBF = 301.004   Chr6 : 32,431,147
0.000 0.087 0.913
rs926594 lBF = 232.853   Chr6 : 32,305,370
0.913 0.087 0.000
rs910052 lBF = 235.906   Chr6 : 32,299,873
0.913 0.087 0.000
rs742582 lBF = 233.643   Chr6 : 32,299,715
0.913 0.087 0.000
rs4576282 lBF = 234.34   Chr6 : 32,312,796
0.913 0.087 0.000
rs9268456 lBF = 206.36   Chr6 : 32,349,946
0.913 0.087 0.000
rs9357140 lBF = 235.704   Chr6 : 32,301,514
0.913 0.087 0.000
rs9268474 lBF = 206.823   Chr6 : 32,357,165
0.913 0.087 0.000
rs9268480 lBF = 205.885   Chr6 : 32,363,844
0.913 0.087 0.000
rs3763307 lBF = 200.492   Chr6 : 32,374,622
0.913 0.087 0.000
rs9268428 lBF = 204.585   Chr6 : 32,344,973
0.913 0.087 0.000
rs9268481 lBF = 204.836   Chr6 : 32,364,356
0.913 0.087 0.000
rs2076541 lBF = 234.121   Chr6 : 32,317,215
0.913 0.087 0.000
rs3817962 lBF = 207.082   Chr6 : 32,368,314
0.913 0.087 0.000
rs9268368 lBF = 233.695   Chr6 : 32,333,955
0.913 0.087 0.000
rs505274 lBF = 233.162   Chr6 : 32,294,992
0.913 0.087 0.000
rs9268418 lBF = 204.537   Chr6 : 32,343,686
0.913 0.087 0.000
rs9268459 lBF = 204.967   Chr6 : 32,350,776
0.913 0.087 0.000
rs9270984 lBF = 225.558   Chr6 : 32,573,991
0.912 0.088 0.000
rs9268429 lBF = 204.835   Chr6 : 32,345,052
0.912 0.088 0.000
rs74176255 lBF = 6.85732   Chr19 : 7,920,771
0.912 0.088 0.000
rs9268516 lBF = 206.395   Chr6 : 32,379,489
0.912 0.088 0.000
rs973037 lBF = 234.248   Chr6 : 32,305,125
0.912 0.088 0.000
rs482194 lBF = 230.879   Chr6 : 32,260,559
0.912 0.088 0.000
rs9379842 lBF = 47.8805   Chr6 : 26,289,310
0.000 0.088 0.912
rs241447 lBF = 113.179   Chr6 : 32,796,751
0.000 0.088 0.912
rs9276922 lBF = 43.0706   Chr6 : 32,881,527
0.000 0.088 0.912
rs547261 lBF = 233.198   Chr6 : 32,282,033
0.912 0.088 0.000
rs6923313 lBF = 118.928   Chr6 : 31,241,370
0.000 0.089 0.911
rs377763 lBF = 302.382   Chr6 : 32,199,144
0.911 0.089 0.000
rs241449 lBF = 112.78   Chr6 : 32,796,653
0.000 0.089 0.911
rs531094 lBF = 224.495   Chr6 : 32,286,102
0.911 0.089 0.000
rs241455 lBF = 114.549   Chr6 : 32,796,019
0.000 0.089 0.911
rs9268301 lBF = 266.74   Chr6 : 32,319,637
0.911 0.089 0.000
rs241454 lBF = 114.601   Chr6 : 32,796,144
0.000 0.089 0.911
rs537757 lBF = 228.568   Chr6 : 32,268,501
0.911 0.089 0.000
rs2076525 lBF = 201.524   Chr6 : 32,370,616
0.911 0.089 0.000
rs241453 lBF = 114.037   Chr6 : 32,796,226
0.000 0.089 0.911
rs241424 lBF = 142.173   Chr6 : 32,804,934
0.910 0.090 0.000
rs3130299 lBF = 64.1226   Chr6 : 32,203,537
0.000 0.090 0.910
rs9348882 lBF = 234.801   Chr6 : 32,301,322
0.910 0.090 0.000
rs241440 lBF = 110.045   Chr6 : 32,797,361
0.000 0.090 0.910
rs485774 lBF = 231.133   Chr6 : 32,290,954
0.910 0.090 0.000
rs9272559 lBF = 157.261   Chr6 : 32,607,124
0.910 0.090 0.000
rs3129934 lBF = 192.051   Chr6 : 32,336,187
0.910 0.090 0.000
rs547077 lBF = 234.953   Chr6 : 32,289,318
0.910 0.090 0.000
rs440261 lBF = 61.2793   Chr6 : 32,198,056
0.000 0.090 0.910
rs574710 lBF = 234.496   Chr6 : 32,288,190
0.909 0.091 0.000
rs525607 lBF = 236.083   Chr6 : 32,292,084
0.909 0.091 0.000
rs2621321 lBF = 114.322   Chr6 : 32,789,480
0.000 0.091 0.909
rs5875328 lBF = 331.092   Chr6 : 31,606,901
0.909 0.091 0.000
rs6356 lBF = 9.07006   Chr11 : 2,190,951
0.909 0.091 0.000
rs12063216 lBF = 36.6366   Chr1 : 114,277,330
0.909 0.091 0.000
rs17034 lBF = 112.984   Chr6 : 32,796,521
0.000 0.091 0.909
rs2736426 lBF = 127.714   Chr6 : 31,745,284
0.000 0.091 0.909
rs2187668 lBF = 393.11   Chr6 : 32,605,884
0.909 0.091 0.000
rs6929776 lBF = 236.948   Chr6 : 32,303,511
0.909 0.091 0.000
rs2022533 lBF = 234.991   Chr6 : 32,307,260
0.909 0.091 0.000
rs9348881 lBF = 236.064   Chr6 : 32,296,842
0.909 0.091 0.000
rs9366793 lBF = 236.252   Chr6 : 32,301,289
0.909 0.091 0.000
Affx-28471303 lBF = 238.022   Chr6 : 32,295,357
0.909 0.091 0.000
rs378088 lBF = 61.8023   Chr6 : 32,196,313
0.000 0.091 0.909
rs3817966 lBF = 198.937   Chr6 : 32,367,847
0.908 0.092 0.000
rs3817963 lBF = 197.964   Chr6 : 32,368,087
0.908 0.092 0.000
rs2516440 lBF = 24.7529   Chr6 : 31,440,497
0.000 0.092 0.908
rs365053 lBF = 58.5247   Chr6 : 32,195,988
0.000 0.092 0.908
rs915894 lBF = 219.818   Chr6 : 32,190,390
0.908 0.092 0.000
rs9272276 lBF = 160.465   Chr6 : 32,603,634
0.908 0.092 0.000
rs9271640 lBF = 222.488   Chr6 : 32,592,200
0.907 0.093 0.000
rs9271366 lBF = 229.528   Chr6 : 32,586,854
0.907 0.093 0.000
rs2040406 lBF = 386.738   Chr6 : 32,603,007
0.907 0.093 0.000
rs10774625 lBF = 134.733   Chr12 : 111,910,219
0.907 0.093 0.000
rs3184504 lBF = 147.788   Chr12 : 111,884,608
0.906 0.094 0.000
rs4766578 lBF = 133.156   Chr12 : 111,904,371
0.000 0.094 0.906
rs653178 lBF = 141.209   Chr12 : 112,007,756
0.906 0.094 0.000
rs4321864 lBF = 289.858   Chr6 : 32,399,187
0.906 0.094 0.000
rs241429 lBF = 122.708   Chr6 : 32,803,840
0.906 0.094 0.000
rs506770 lBF = 145.133   Chr6 : 31,785,228
0.000 0.095 0.905
rs2071538 lBF = 45.2526   Chr6 : 32,818,678
0.000 0.095 0.905
rs1055569 lBF = 24.3332   Chr6 : 31,440,082
0.000 0.095 0.905
rs7310615 lBF = 134.377   Chr12 : 111,865,049
0.000 0.095 0.905
rs597808 lBF = 138.181   Chr12 : 111,973,358
0.000 0.095 0.905
rs35344500 lBF = 333.689   Chr6 : 32,609,525
0.905 0.095 0.000
rs3806157 lBF = 141.884   Chr6 : 32,373,801
0.905 0.095 0.000
rs7137828 lBF = 136.212   Chr12 : 111,932,800
0.000 0.095 0.905
rs9268606 lBF = 241.581   Chr6 : 32,400,070
0.904 0.096 0.000
rs9273076 lBF = 225.981   Chr6 : 32,612,301
0.904 0.096 0.000
rs9379844 lBF = 48.0451   Chr6 : 26,291,527
0.000 0.096 0.904
rs3135350 lBF = 216.139   Chr6 : 32,392,981
0.904 0.096 0.000
rs3763311 lBF = 203.85   Chr6 : 32,376,176
0.904 0.096 0.000
rs9275371 lBF = 239.231   Chr6 : 32,668,296
0.903 0.097 0.000
rs9276612 lBF = 140.702   Chr6 : 32,742,712
0.903 0.097 0.000
rs9272308 lBF = 332.362   Chr6 : 32,603,906
0.903 0.097 0.000
rs2508015 lBF = 169.83   Chr6 : 31,010,200
0.903 0.097 0.000
rs674313 lBF = 146.852   Chr6 : 32,578,082
0.903 0.097 0.000
rs642093 lBF = 323.201   Chr6 : 32,582,075
0.903 0.097 0.000
rs3129763 lBF = 328.807   Chr6 : 32,590,925
0.903 0.097 0.000
rs3763348 lBF = 78.4358   Chr6 : 32,822,907
0.903 0.097 0.000
rs10885 lBF = 337.848   Chr6 : 31,604,591
0.903 0.097 0.000
rs9265549 lBF = 194.028   Chr6 : 31,298,240
0.903 0.097 0.000
rs602875 lBF = 323.871   Chr6 : 32,573,629
0.903 0.097 0.000
rs9275614 lBF = 213.979   Chr6 : 32,684,257
0.903 0.097 0.000
rs9270493 lBF = 326.186   Chr6 : 32,559,110
0.902 0.098 0.000
rs3916765 lBF = 217.868   Chr6 : 32,685,550
0.902 0.098 0.000
rs1125000 lBF = 69.6829   Chr6 : 26,287,256
0.902 0.098 0.000
rs2071544 lBF = 94.4367   Chr6 : 32,806,121
0.902 0.098 0.000
rs2855812 lBF = 350.197   Chr6 : 31,472,720
0.902 0.098 0.000
rs2736157 lBF = 327.457   Chr6 : 31,600,820
0.902 0.098 0.000
rs9271541 lBF = 326.542   Chr6 : 32,590,070
0.902 0.098 0.000
rs17192225 lBF = 58.7777   Chr6 : 31,230,438
0.902 0.098 0.000
rs17885785 lBF = 26.9923   Chr11 : 2,167,850
0.000 0.098 0.902
rs4413654 lBF = 32.6832   Chr6 : 31,441,349
0.000 0.098 0.902
rs2074488 lBF = 59.8468   Chr6 : 31,240,431
0.902 0.098 0.000
rs3115665 lBF = 337.342   Chr6 : 31,589,264
0.902 0.098 0.000
rs6930981 lBF = 75.4456   Chr6 : 32,826,450
0.901 0.099 0.000
rs3130627 lBF = 337.805   Chr6 : 31,600,851
0.901 0.099 0.000
rs3130618 lBF = 335.092   Chr6 : 31,632,134
0.901 0.099 0.000
rs3115663 lBF = 338.64   Chr6 : 31,601,843
0.901 0.099 0.000
rs3828886 lBF = 31.6595   Chr6 : 31,440,552
0.000 0.099 0.901
rs11229 lBF = 338.99   Chr6 : 31,603,770
0.901 0.099 0.000
rs3117583 lBF = 338.249   Chr6 : 31,619,576
0.901 0.099 0.000
rs3130070 lBF = 334.536   Chr6 : 31,591,808
0.901 0.099 0.000
rs2251830 lBF = 148.937   Chr6 : 31,016,978
0.901 0.099 0.000
rs2523864 lBF = 147.734   Chr6 : 31,018,546
0.901 0.099 0.000
rs181997 lBF = 16.7883   Chr6 : 32,900,718
0.000 0.099 0.901
rs3835263 lBF = 37.1677   Chr1 : 114,240,319
0.901 0.099 0.000
rs3819714 lBF = 48.4445   Chr6 : 32,804,217
0.000 0.099 0.901
rs2394251 lBF = 47.8031   Chr6 : 29,943,688
0.000 0.100 0.900
rs2523865 lBF = 148.081   Chr6 : 31,018,448
0.900 0.100 0.000
rs2523663 lBF = 91.8832   Chr6 : 31,439,740
0.000 0.100 0.900
rs35647108 lBF = 53.922   Chr6 : 31,274,449
0.900 0.100 0.000
rs3806156 lBF = 139.984   Chr6 : 32,373,698
0.900 0.100 0.000
rs2517544 lBF = 195.736   Chr6 : 31,009,508
0.900 0.100 0.000
rs2534674 lBF = 90.8041   Chr6 : 31,465,103
0.000 0.100 0.900
rs2274153 lBF = 21.8177   Chr6 : 33,857,482
0.900 0.100 0.000
rs7383287 lBF = 68.1186   Chr6 : 32,783,086
0.899 0.101 0.000
rs2076523 lBF = 139.68   Chr6 : 32,370,835
0.899 0.101 0.000
rs6903171 lBF = 28.3887   Chr6 : 33,864,137
0.899 0.101 0.000
rs2523957 lBF = 52.3043   Chr6 : 29,940,260
0.000 0.101 0.899
rs2621383 lBF = 85.7764   Chr6 : 32,759,335
0.000 0.101 0.899
rs9268499 lBF = 201.124   Chr6 : 32,375,695
0.899 0.101 0.000
rs9469220 lBF = 239.257   Chr6 : 32,658,310
0.000 0.101 0.899
rs2857161 lBF = 85.2086   Chr6 : 32,759,297
0.000 0.101 0.899
rs241448 lBF = 108.484   Chr6 : 32,796,685
0.000 0.102 0.898
rs9272535 lBF = 325.29   Chr6 : 32,606,756
0.898 0.102 0.000
rs2071477 lBF = 78.7785   Chr6 : 32,825,348
0.898 0.102 0.000
rs1480383 lBF = 171.673   Chr6 : 32,740,856
0.897 0.103 0.000
rs435766 lBF = 51.2269   Chr6 : 29,939,852
0.000 0.103 0.897
rs7453498 lBF = 257.298   Chr6 : 32,446,717
0.897 0.103 0.000
rs1053924 lBF = 133.698   Chr6 : 32,120,715
0.000 0.103 0.897
rs2844767 lBF = 63.2583   Chr6 : 30,222,256
0.897 0.103 0.000
rs4713598 lBF = 122.097   Chr6 : 32,806,786
0.897 0.103 0.000
rs3094636 lBF = 60.4038   Chr6 : 30,211,755
0.000 0.103 0.897
rs4713600 lBF = 80.7066   Chr6 : 32,822,858
0.897 0.103 0.000
rs2239704 lBF = 90.572   Chr6 : 31,540,141
0.000 0.103 0.897
rs2516500 lBF = 218.481   Chr6 : 31,453,640
0.897 0.103 0.000
rs1383267 lBF = 79.4978   Chr6 : 32,833,646
0.897 0.103 0.000
rs1871667 lBF = 78.9959   Chr6 : 32,834,229
0.897 0.103 0.000
rs1351383 lBF = 79.9659   Chr6 : 32,822,269
0.896 0.103 0.000
rs2071470 lBF = 109.115   Chr6 : 32,784,753
0.000 0.104 0.896
rs2735079 lBF = 52.4038   Chr6 : 29,938,932
0.000 0.104 0.896
rs2071474 lBF = 109.399   Chr6 : 32,782,582
0.000 0.104 0.896
rs2074491 lBF = 57.2926   Chr6 : 31,239,896
0.896 0.104 0.000
rs6938130 lBF = 76.4773   Chr6 : 32,831,247
0.896 0.104 0.000
rs9272215 lBF = 326.395   Chr6 : 32,602,105
0.896 0.104 0.000
rs2248372 lBF = 103.651   Chr6 : 31,446,466
0.000 0.104 0.896
rs2256919 lBF = 52.8824   Chr6 : 29,940,750
0.000 0.104 0.896
rs6924102 lBF = 120.062   Chr6 : 32,811,383
0.896 0.104 0.000
rs2071465 lBF = 151.16   Chr6 : 32,805,470
0.896 0.104 0.000
rs2523676 lBF = 52.773   Chr6 : 31,435,991
0.896 0.104 0.000
rs2857602 lBF = 89.4881   Chr6 : 31,533,378
0.000 0.105 0.895
rs2844484 lBF = 87.9182   Chr6 : 31,536,224
0.000 0.105 0.895
rs928815 lBF = 87.1834   Chr6 : 31,531,215
0.000 0.105 0.895
rs6903608 lBF = 251.273   Chr6 : 32,428,285
0.000 0.105 0.895
rs2071472 lBF = 106.363   Chr6 : 32,784,620
0.000 0.105 0.895
rs10858000 lBF = 25.2805   Chr1 : 114,075,796
0.895 0.105 0.000
rs6923504 lBF = 250.735   Chr6 : 32,428,186
0.000 0.105 0.895
rs2285802 lBF = 57.9704   Chr6 : 30,209,099
0.000 0.105 0.895
rs7767288 lBF = 77.2447   Chr6 : 32,830,013
0.894 0.106 0.000
rs9268219 lBF = 356.694   Chr6 : 32,284,108
0.894 0.106 0.000
rs9275601 lBF = 161.644   Chr6 : 32,682,664
0.893 0.107 0.000
rs9272630 lBF = 162.464   Chr6 : 32,608,150
0.893 0.107 0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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