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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3132943
log Bayes Factor = 217.382
Chromosome 6   position 32,308,465  (GRCh37) Explore rs3132943 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E11.3 With ophthalmic complications
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
E70-E90 Metabolic disorders
0.000 0.001 0.999
J33 Nasal polyp
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.001 0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.001 0.999
J33.0 Polyp of nasal cavity
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.001 0.999
J33.9 Nasal polyp, unspecified
0.000 0.002 0.998
# Top node
0.000 0.002 0.998
M07 Psoriatic and enteropathic arthropathies
0.000 0.003 0.997
G35-G37 Demyelinating diseases of the central nervous system
0.997 0.003 0.000
E14.3 With ophthalmic complications
0.000 0.004 0.996
Chapter VII Diseases of the eye and adnexa
0.000 0.004 0.996
G37 Other demyelinating diseases of central nervous system
0.996 0.004 0.000
L40.9 Psoriasis, unspecified
0.000 0.004 0.996
M07.3 Other psoriatic arthropathies
0.000 0.004 0.996
M35 Other systemic involvement of connective tissue
0.000 0.004 0.996
I10 Essential (primary) hypertension
0.000 0.005 0.995
I10-I15 Hypertensive diseases
0.000 0.005 0.995
G37.9 Demyelinating disease of central nervous system, unspecified
0.995 0.005 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.006 0.994
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.006 0.994
J33.8 Other polyp of sinus
0.000 0.008 0.992
E10.5 With peripheral circulatory complications
0.000 0.009 0.991
Chapter IX Diseases of the circulatory system
0.000 0.009 0.991
M20-M25 Other joint disorders
0.000 0.009 0.991
E11.1 With ketoacidosis
0.000 0.009 0.991
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.012 0.988
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.017 0.983
L43 Lichen planus
0.000 0.018 0.982
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.023 0.977
I22 Subsequent myocardial infarction
0.000 0.027 0.973
H34 Retinal vascular occlusions
0.000 0.028 0.972
E10.2 With renal complications
0.000 0.028 0.972
I20-I25 Ischaemic heart diseases
0.000 0.029 0.971
E06 Thyroiditis
0.000 0.038 0.962
H40-H42 Glaucoma
0.000 0.043 0.957
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.044 0.956
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.044 0.956
L43.9 Lichen planus, unspecified
0.000 0.045 0.955
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.045 0.955
M34 Systemic sclerosis
0.000 0.048 0.952
I12 Hypertensive renal disease
0.000 0.048 0.952
E10.8 With unspecified complications
0.000 0.051 0.949
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.051 0.949
E06.3 Autoimmune thyroiditis
0.000 0.060 0.940
E11.5 With peripheral circulatory complications
0.000 0.062 0.938
E07 Other disorders of thyroid
0.000 0.064 0.936
H35 Other retinal disorders
0.000 0.065 0.935
E10.0 With coma
0.000 0.065 0.935
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.066 0.934
M06.0 Seronegative rheumatoid arthritis
0.000 0.067 0.933
I12.9 Hypertensive renal disease without renal failure
0.000 0.069 0.931
E78.2 Mixed hyperlipidaemia
0.000 0.071 0.929
H40 Glaucoma
0.000 0.072 0.928
H40.9 Glaucoma, unspecified
0.000 0.074 0.926
M45-M49 Spondylopathies
0.000 0.076 0.924
M45 Ankylosing spondylitis
0.000 0.078 0.922
E11.2 With renal complications
0.000 0.080 0.920
M06.3 Rheumatoid nodule
0.000 0.082 0.918
M06.4 Inflammatory polyarthropathy
0.000 0.087 0.913
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.095 0.905
H35.8 Other specified retinal disorders
0.000 0.099 0.901
H34.2 Other retinal artery occlusions
0.000 0.100 0.900
E78.1 Pure hyperglyceridaemia
0.000 0.102 0.898
M65-M68 Disorders of synovium and tendon
0.000 0.105 0.895
H35.4 Peripheral retinal degeneration
0.000 0.110 0.890
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.112 0.888
E88 Other metabolic disorders
0.000 0.116 0.884
E07.9 Disorder of thyroid, unspecified
0.000 0.119 0.881
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.124 0.876
M34.1 CR(E)ST syndrome
0.000 0.127 0.873
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.128 0.872
H34.8 Other retinal vascular occlusions
0.000 0.137 0.863
G37.8 Other specified demyelinating diseases of central nervous system
0.863 0.137 0.000
M65 Synovitis and tenosynovitis
0.000 0.137 0.863
M35.1 Other overlap syndromes
0.000 0.138 0.862
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.140 0.860
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.144 0.856
M34.9 Systemic sclerosis, unspecified
0.000 0.145 0.855
L40.8 Other psoriasis
0.000 0.147 0.853
L43.8 Other lichen planus
0.000 0.150 0.850
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.151 0.849
E10.6 With other specified complications
0.000 0.152 0.848
M35.7 Hypermobility syndrome
0.000 0.158 0.842
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.161 0.839
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.163 0.837
M86-M90 Other osteopathies
0.000 0.167 0.833
E11.8 With unspecified complications
0.000 0.171 0.829
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.175 0.825
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.176 0.824
E89.0 Postprocedural hypothyroidism
0.000 0.177 0.823
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.179 0.821
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.185 0.815
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.187 0.813
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.190 0.810
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.193 0.807
M86 Osteomyelitis
0.000 0.197 0.803
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.197 0.803
M06.34 Rheumatoid nodule (Hand)
0.000 0.206 0.794
I15 Secondary hypertension
0.000 0.210 0.790
E14.4 With neurological complications
0.000 0.211 0.789
M86.9 Osteomyelitis, unspecified
0.000 0.213 0.787
E11.4 With neurological complications
0.000 0.214 0.786
E03.8 Other specified hypothyroidism
0.000 0.214 0.786
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.220 0.780
H35.6 Retinal haemorrhage
0.000 0.220 0.780
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.225 0.775
H43-H45 Disorders of vitreous body and globe
0.000 0.229 0.771
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.233 0.767
I22.8 Subsequent myocardial infarction of other sites
0.000 0.233 0.767
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.236 0.764
E74 Other disorders of carbohydrate metabolism
0.000 0.238 0.762
M35.2 Behcet's disease
0.000 0.239 0.760
M30 Polyarteritis nodosa and related conditions
0.000 0.242 0.758
E11.6 With other specified complications
0.000 0.243 0.757
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.243 0.757
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.755 0.245 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.248 0.752
E14.5 With peripheral circulatory complications
0.000 0.248 0.751
H34.1 Central retinal artery occlusion
0.000 0.249 0.751
H35.7 Separation of retinal layers
0.000 0.249 0.751
I70 Atherosclerosis
0.000 0.252 0.748
H40.4 Glaucoma secondary to eye inflammation
0.000 0.255 0.745
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.258 0.742
H34.9 Retinal vascular occlusion, unspecified
0.000 0.260 0.740
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.261 0.739
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.263 0.737
M31 Other necrotising vasculopathies
0.000 0.264 0.736
H40.5 Glaucoma secondary to other eye disorders
0.000 0.266 0.734
I11 Hypertensive heart disease
0.000 0.267 0.733
L40.3 Pustulosis palmaris et plantaris
0.000 0.269 0.731
M14 Arthropathies in other diseases classified elsewhere
0.000 0.269 0.731
E14.2 Withrenal complications
0.000 0.270 0.730
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.275 0.725
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.276 0.724
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.277 0.723
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.278 0.722
H35.2 Other proliferative retinopathy
0.000 0.281 0.719
H30 Chorioretinal inflammation
0.000 0.281 0.719
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.282 0.718
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E07.8 Other specified disorders of thyroid
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.716
L41 Parapsoriasis
0.000 0.283 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.716
E77 Disorders of glycoprotein metabolism
0.000 0.283 0.716
E76 Disorders of glycosaminoglycan metabolism
0.000 0.283 0.716
E72 Other disorders of amino-acid metabolism
0.000 0.283 0.716
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.283 0.716
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.283 0.716
J33.1 Polypoid sinus degeneration
0.000 0.284 0.716
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.285 0.715
M07.5 Arthropathy in ulcerative colitis
0.000 0.285 0.715
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.285 0.715
M07.2 Psoriatic spondylitis
0.000 0.285 0.715
M07.1 Arthritis mutilans
0.000 0.285 0.715
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.285 0.715
E83 Disorders of mineral metabolism
0.326 0.286 0.388
G37.5 Concentric sclerosis [Balo]
0.714 0.286 0.000
G37.4 Subacute necrotising myelitis
0.714 0.286 0.000
G37.2 Central pontine myelinolysis
0.714 0.286 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.286 0.000
G37.0 Diffuse sclerosis
0.714 0.286 0.000
M07.38 Other psoriatic arthropathies (Other)
0.000 0.286 0.714
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.286 0.714
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.286 0.714
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.286 0.714
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.286 0.714
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.286 0.714
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.286 0.714
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.286 0.714
M35.5 Multifocal fibrosclerosis
0.000 0.286 0.714
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.286 0.714
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.286 0.714
I13 Hypertensive heart and renal disease
0.000 0.286 0.713
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.287 0.713
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.289 0.711
I00-I02 Acute rheumatic fever
0.000 0.289 0.711
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.290 0.710
G36 Other acute disseminated demyelination
0.710 0.290 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.292 0.708
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.295 0.705
L43.3 Subacute (active) lichen planus
0.000 0.296 0.704
L43.2 Lichenoid drug reaction
0.000 0.296 0.704
L43.1 Bullous lichen planus
0.000 0.296 0.704
L43.0 Hypertrophic lichen planus
0.000 0.296 0.704
E88.8 Other specified metabolic disorders
0.000 0.297 0.703
H33 Retinal detachments and breaks
0.000 0.297 0.703
E88.2 Lipomatosis, not elsewhere classified
0.000 0.298 0.702
H43 Disorders of vitreous body
0.000 0.298 0.702
E70 Disorders of aromatic amino-acid metabolism
0.000 0.300 0.700
H34.0 Transient retinal artery occlusion
0.000 0.303 0.697
M34.8 Other forms of systemic sclerosis
0.000 0.305 0.695
L40.0 Psoriasis vulgaris
0.000 0.305 0.695
M12 Other specific arthropathies
0.000 0.306 0.694
E79 Disorders of purine and pyrimidine metabolism
0.000 0.309 0.691
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.309 0.691
E06.5 Other chronic thyroiditis
0.000 0.310 0.689
E06.4 Drug-induced thyroiditis
0.000 0.310 0.689
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.310 0.689
E06.1 Subacute thyroiditis
0.000 0.310 0.689
E06.0 Acute thyroiditis
0.000 0.310 0.689
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.311 0.689
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.312 0.688
E78.4 Other hyperlipidaemia
0.000 0.314 0.686
H42 Glaucoma in diseases classified elsewhere
0.000 0.314 0.686
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.317 0.683
M34.0 Progressive systemic sclerosis
0.000 0.317 0.683
E16.1 Other hypoglycaemia
0.000 0.321 0.678
E40-E46 Malnutrition
0.000 0.323 0.677
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.328 0.672
Chapter VIII Diseases of the ear and mastoid process
0.000 0.328 0.672
E07.1 Dyshormogenetic goitre
0.000 0.329 0.671
E07.0 Hypersecretion of calcitonin
0.000 0.329 0.671
H35.1 Retinopathy of prematurity
0.000 0.329 0.671
M65.1 Other infective (teno)synovitis
0.000 0.330 0.670
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.331 0.669
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.331 0.669
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.331 0.669
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.331 0.669
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.331 0.669
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.331 0.669
E13 Other specified diabetes mellitus
0.000 0.331 0.669
M07.6 Other enteropathic arthropathies
0.000 0.332 0.667
M49 Spondylopathies in diseases classified elsewhere
0.000 0.333 0.667
E84 Cystic fibrosis
0.000 0.334 0.666
H40.6 Glaucoma secondary to drugs
0.000 0.334 0.665
H40.3 Glaucoma secondary to eye trauma
0.000 0.334 0.665
M91-M94 Chondropathies
0.000 0.337 0.663
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.338 0.662
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.339 0.661
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.339 0.661
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.339 0.661
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.339 0.661
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.339 0.661
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.339 0.661
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.342 0.658
M06.38 Rheumatoid nodule (Other)
0.000 0.342 0.658
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.342 0.658
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.342 0.658
M06.33 Rheumatoid nodule (Forearm)
0.000 0.342 0.658
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.342 0.658
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.342 0.658
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.342 0.658
E89.4 Postprocedural ovarian failure
0.000 0.344 0.656
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.345 0.655
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.345 0.655
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.345 0.655
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.345 0.655
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.345 0.655
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.345 0.655
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.345 0.655
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.345 0.655
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.345 0.655
M32 Systemic lupus erythematosus
0.000 0.347 0.653
I73 Other peripheral vascular diseases
0.000 0.350 0.650
I70.0 Atherosclerosis of aorta
0.000 0.352 0.648
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.354 0.646
M11 Other crystal arthropathies
0.000 0.356 0.644
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.356 0.644
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.357 0.643
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.358 0.641
L10-L14 Bullous disorders
0.000 0.358 0.641
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.361 0.639
H33.3 Retinal breaks without detachment
0.000 0.361 0.639
E88.3 Tumour lysis syndrome
0.000 0.364 0.636
E88.9 Metabolic disorder, unspecified
0.000 0.366 0.634
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.366 0.634
H60-H62 Diseases of external ear
0.000 0.366 0.634
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.367 0.633
M80-M85 Disorders of bone density and structure
0.000 0.367 0.632
E89.3 Postprocedural hypopituitarism
0.000 0.371 0.629
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.372 0.628
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.372 0.628
E89.5 Postprocedural testicular hypofunction
0.000 0.372 0.628
E89.1 Postprocedural hypoinsulinaemia
0.000 0.372 0.628
I73.9 Peripheral vascular disease, unspecified
0.000 0.375 0.625
M86.98 Osteomyelitis, unspecified (Other)
0.000 0.375 0.625
E06.9 Thyroiditis, unspecified
0.000 0.377 0.623
L57.0 Actinic keratosis
0.000 0.379 0.621
H04 Disorders of lachrymal system
0.000 0.380 0.619
M65.2 Calcific tendinitis
0.000 0.381 0.618
M65.0 Abscess of tendon sheath
0.000 0.381 0.618
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.382 0.618
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.382 0.618
I15.9 Seconday hypertension, unspecified
0.000 0.382 0.617
L20-L30 Dermatitis and eczema
0.000 0.384 0.616
M66 Spontaneous rupture of synovium and tendon
0.000 0.385 0.615
M33 Dermatopolymyositis
0.000 0.385 0.614
L42 Pityriasis rosea
0.000 0.386 0.614
I15.1 Hypertension secondary to other renal disorders
0.000 0.388 0.612
H43.3 Other vitreous opacities
0.000 0.391 0.609
L80 Vitiligo
0.000 0.393 0.607
M88 Paget's disease of bone [osteitis deformans]
0.000 0.393 0.607
E05.8 Other thyrotoxicosis
0.000 0.393 0.607
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.396 0.604
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.397 0.603
H40.0 Glaucoma suspect
0.000 0.400 0.600
I21 Acute myocardial infarction
0.000 0.401 0.599
M31.6 Other giant cell arteritis
0.000 0.403 0.597
H43.9 Disorder of vitreous body, unspecified
0.000 0.404 0.596
E73 Lactose intolerance
0.000 0.404 0.596
M14.6 Neuropathic arthropathy
0.000 0.405 0.595
I23 Certain current complications following acute myocardial infarction
0.000 0.406 0.594
L28 Lichen simplex chronicus and prurigo
0.000 0.407 0.593
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.408 0.591
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.408 0.591
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.408 0.591
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.408 0.591
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.408 0.591
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.408 0.591
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.408 0.591
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.408 0.591
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.409 0.591
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.411 0.589
H46 Optic neuritis
0.000 0.412 0.588
M90 Osteopathies in diseases classified elsewhere
0.000 0.414 0.586
E89.2 Postprocedural hypoparathyroidism
0.000 0.415 0.585
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.415 0.585
E20-E35 Disorders of other endocrine glands
0.000 0.416 0.584
H61 Other disorders of external ear
0.000 0.417 0.583
D64.9 Anaemia, unspecified
0.000 0.418 0.582
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.418 0.581
M35.0 Sicca syndrome [Sjogren]
0.000 0.419 0.581
M60-M63 Disorders of muscles
0.000 0.420 0.580
M86.6 Other chronic osteomyelitis
0.000 0.421 0.579
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.422 0.577
M86.5 Other chronic haematogenous osteomyelitis
0.000 0.424 0.576
M86.4 Chronic osteomyelitis with draining sinus
0.000 0.424 0.576
M86.3 Chronic multifocal osteomyelitis
0.000 0.424 0.576
M86.2 Subacute osteomyelitis
0.000 0.424 0.576
M86.0 Acute haematogenous osteomyelitis
0.000 0.424 0.576
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.427 0.572
E65-E68 Obesity and other hyperalimentation
0.000 0.428 0.572
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.430 0.570
D64 Other anaemias
0.000 0.430 0.570
L28.0 Lichen simplex chronicus
0.000 0.431 0.569
I15.8 Other secondary hypertension
0.000 0.433 0.567
I15.2 Hypertension secondary to endocrine disorders
0.000 0.433 0.567
M31.9 Necrotising vasculopathy, unspecified
0.000 0.433 0.567
D60-D64 Aplastic and other anaemias
0.000 0.433 0.567
M80 Osteoporosis with pathological fracture
0.000 0.434 0.565
M30.0 Polyarteritis nodosa
0.000 0.435 0.565
M82 Osteoporosis in diseases classified elsewhere
0.000 0.435 0.565
M86.93 Osteomyelitis, unspecified (Forearm)
0.000 0.435 0.564
M86.92 Osteomyelitis, unspecified (Upper arm)
0.000 0.435 0.564
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.000 0.435 0.564
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.000 0.435 0.564
E80.4 Gilbert's syndrome
0.000 0.436 0.564
M00-M03 Infectious arthropathies
0.000 0.436 0.564
M86.96 Osteomyelitis, unspecified (Lower leg)
0.000 0.437 0.563
E11.0 With coma
0.000 0.438 0.562
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.438 0.562
H40.1 Primary open-angle glaucoma
0.000 0.438 0.562
M10 Gout
0.000 0.438 0.562
E03.1 Congenital hypothyroidism without goitre
0.000 0.440 0.560
M86.1 Other acute osteomyelitis
0.000 0.447 0.553
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.447 0.552
I15.0 Renovascular hypertension
0.000 0.448 0.552
H33.4 Traction detachment of retina
0.000 0.448 0.552
H35.5 Hereditary retinal dystrophy
0.000 0.450 0.550
L55 Sunburn
0.000 0.450 0.550
H04.8 Other disorders of lachrymal system
0.000 0.450 0.550
I24 Other acute ischaemic heart diseases
0.000 0.451 0.549
I21.9 Acute myocardial infarction, unspecified
0.000 0.452 0.548
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.454 0.546
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.454 0.546
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.454 0.546
E74.2 Disorders of galactose metabolism
0.000 0.454 0.546
E74.1 Disorders of fructose metabolism
0.000 0.454 0.546
E74.0 Glycogen storage disease
0.000 0.454 0.546
I12.0 Hypertensive renal disease with renal failure
0.000 0.455 0.545
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.455 0.545
L85 Other epidermal thickening
0.000 0.456 0.544
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.456 0.543
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.456 0.543
M30.2 Juvenile polyarteritis
0.000 0.456 0.543
H43.1 Vitreous haemorrhage
0.000 0.457 0.543
M31.3 Wegener's granulomatosis
0.000 0.457 0.542
E78.8 Other disorders of lipoprotein metabolism
0.000 0.462 0.538
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.462 0.538
H60 Otitis externa
0.000 0.463 0.537
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.463 0.537
I70.8 Atherosclerosis of other arteries
0.000 0.467 0.533
M31.1 Thrombotic microangiopathy
0.000 0.467 0.533
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.467 0.533
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.470 0.530
M86.8 Other osteomyelitis
0.000 0.471 0.528
H43.2 Crystalline deposits in vitreous body
0.000 0.472 0.528
M31.8 Other specified necrotising vasculopathies
0.000 0.473 0.527
M31.7 Microscopic polyangiitis
0.000 0.473 0.527
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.473 0.527
M31.2 Lethal midline granuloma
0.000 0.473 0.527
M86.94 Osteomyelitis, unspecified (Hand)
0.000 0.474 0.526
H61.0 Perichondritis of external ear
0.000 0.475 0.525
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.476 0.524
M14.4 Arthropathy in amyloidosis
0.000 0.476 0.524
M14.3 Lipoid dermatoarthritis
0.000 0.476 0.524
M14.2 Diabetic arthropathy
0.000 0.476 0.524
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.476 0.524
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.476 0.524
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.000 0.476 0.523
E80.6 Other disorders of bilirubin metabolism
0.000 0.477 0.523
L94 Other localised connective tissue disorders
0.000 0.479 0.521
E28 Ovarian dysfunction
0.000 0.480 0.520
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.480 0.519
I79.1 Aortitis in diseases classified elsewhere
0.000 0.480 0.519
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.480 0.519
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.481 0.519
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.482 0.518
E80.5 Crigler-Najjar syndrome
0.000 0.482 0.518
E80.3 Defects of catalase and peroxydase
0.000 0.482 0.518
E80.1 Porphyria cutanea tarda
0.000 0.482 0.518
E80.0 Hereditary erythropoietic porphyria
0.000 0.482 0.518
H30.9 Chorioretinal inflammation, unspecified
0.000 0.482 0.518
I77 Other disorders of arteries and arterioles
0.000 0.483 0.517

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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