TreeWAS – Variant ID: rs2523451

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
L40 Psoriasis	0.000	0.001	0.999
E05.0 Thyrotoxicosis with diffuse goitre	0.999	0.001	0.000
M05-M14 Inflammatory polyarthropathies	0.999	0.001	0.000
L40.5 Arthropathic psoriasis	0.000	0.002	0.998
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.998	0.002	0.000
E20-E35 Disorders of other endocrine glands	0.997	0.003	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.997	0.003	0.000
D64.9 Anaemia, unspecified	0.995	0.005	0.000
D64 Other anaemias	0.994	0.006	0.000
D60-D64 Aplastic and other anaemias	0.994	0.006	0.000
# Top node	0.994	0.006	0.000
E27 Other disorders of adrenal gland	0.994	0.006	0.000
K90 Intestinal malabsorption	0.994	0.006	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.994	0.006	0.000
E27.1 Primary adrenocortical insufficiency	0.993	0.007	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.993	0.007	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.992	0.008	0.000
E14.9 Without complications	0.991	0.009	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.991	0.009	0.000
E16 Other disorders of pancreatic internal secretion	0.988	0.012	0.000
M05 Seropositive rheumatoid arthritis	0.987	0.013	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.016	0.984
Chapter I Certain infectious and parasitic diseases	0.983	0.017	0.000
E10.4 With neurological complications	0.983	0.017	0.000
K75 Other inflammatory liver diseases	0.981	0.019	0.000
E14.3 With ophthalmic complications	0.980	0.020	0.000
E83.1 Disorders of iron metabolism	0.000	0.020	0.980
B25-B34 Other viral diseases	0.980	0.020	0.000
K70-K77 Diseases of liver	0.980	0.020	0.000
K75.4 Autoimmune hepatitis	0.979	0.021	0.000
K90-K93 Other diseases of the digestive system	0.979	0.021	0.000
Chapter XI Diseases of the digestive system	0.978	0.022	0.000
B34 Viral infection of unspecified site	0.975	0.025	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.975	0.025	0.000
E16.2 Hypoglycaemia, unspecified	0.975	0.025	0.000
B34.9 Viral infection, unspecified	0.972	0.028	0.000
K73 Chronic hepatitis, not elsewhere classified	0.972	0.028	0.000
E10.0 With coma	0.972	0.028	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.971	0.029	0.000
E10.2 With renal complications	0.968	0.032	0.000
M35.0 Sicca syndrome [Sjogren]	0.968	0.032	0.000
M35 Other systemic involvement of connective tissue	0.967	0.033	0.000
B35-B49 Mycoses	0.965	0.035	0.000
M20-M25 Other joint disorders	0.962	0.038	0.000
L40.0 Psoriasis vulgaris	0.000	0.051	0.949
K75.8 Other specified inflammatory liver diseases	0.948	0.052	0.000
K73.9 Chronic hepatitis, unspecified	0.948	0.052	0.000
M34 Systemic sclerosis	0.941	0.059	0.000
B37 Candidiasis	0.934	0.066	0.000
J33.0 Polyp of nasal cavity	0.924	0.076	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.924	0.076	0.000
B37.9 Candidiasis, unspecified	0.923	0.077	0.000
J33 Nasal polyp	0.915	0.085	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.914	0.086	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.903	0.097	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.903	0.097	0.000
J33.9 Nasal polyp, unspecified	0.902	0.098	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.900	0.100	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.898	0.102	0.000
M35.1 Other overlap syndromes	0.882	0.118	0.000
J45 Asthma	0.879	0.121	0.000
D62 Acute posthaemorrhagic anaemia	0.877	0.123	0.000
E23 Hypofunction and other disorders of pituitary gland	0.876	0.124	0.000
H36.0 Diabetic retinopathy	0.874	0.126	0.000
E14.8 With unspecified complications	0.873	0.127	0.000
M06.3 Rheumatoid nodule	0.873	0.127	0.000
M45 Ankylosing spondylitis	0.019	0.128	0.853
H36 Retinal disorders in diseases classified elsewhere	0.870	0.130	0.000
H30-H36 Disorders of choroid and retina	0.868	0.132	0.000
M10 Gout	0.868	0.132	0.000
M34.9 Systemic sclerosis, unspecified	0.860	0.140	0.000
M32 Systemic lupus erythematosus	0.856	0.144	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.854	0.146	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.852	0.148	0.000
K90.8 Other intestinal malabsorption	0.852	0.148	0.000
Chapter VIII Diseases of the ear and mastoid process	0.851	0.149	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.847	0.153	0.000
E23.2 Diabetes insipidus	0.846	0.154	0.000
B35 Dermatophytosis	0.845	0.155	0.000
H34 Retinal vascular occlusions	0.842	0.158	0.000
E22 Hyperfunction of pituitary gland	0.841	0.159	0.000
B25 Cytomegaloviral disease	0.836	0.164	0.000
E10.6 With other specified complications	0.835	0.164	0.000
E14.6 With other specified complications	0.835	0.165	0.000
M34.1 CR(E)ST syndrome	0.833	0.167	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.830	0.170	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.004	0.172	0.824
E10.8 With unspecified complications	0.827	0.173	0.000
M86-M90 Other osteopathies	0.826	0.174	0.000
M35.3 Polymyalgia rheumatica	0.825	0.175	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.825	0.175	0.000
E14.2 Withrenal complications	0.824	0.176	0.000
M05.8 Other seropositive rheumatoid arthritis	0.822	0.178	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.817	0.183	0.000
E10.5 With peripheral circulatory complications	0.813	0.187	0.000
A15-A19 Tuberculosis	0.812	0.188	0.000
K90.9 Intestinal malabsorption, unspecified	0.809	0.191	0.000
D61 Other aplastic anaemias	0.808	0.192	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.807	0.193	0.000
E14.1 With ketoacidosis	0.807	0.193	0.000
E20 Hypoparathyroidism	0.804	0.196	0.000
D80-D89 Certain disorders involving the immune mechanism	0.798	0.202	0.000
M34.8 Other forms of systemic sclerosis	0.797	0.203	0.000
Chapter VII Diseases of the eye and adnexa	0.796	0.204	0.000
E28 Ovarian dysfunction	0.795	0.205	0.000
E07 Other disorders of thyroid	0.792	0.208	0.000
E10.7 With multiple complications	0.791	0.208	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.789	0.211	0.000
B33 Other viral diseases, not elsewhere classified	0.788	0.212	0.000
Chapter X Diseases of the respiratory system	0.788	0.212	0.000
J40-J47 Chronic lower respiratory diseases	0.786	0.214	0.000
H60-H62 Diseases of external ear	0.786	0.214	0.000
B44 Aspergillosis	0.784	0.216	0.000
H34.2 Other retinal artery occlusions	0.783	0.217	0.000
M65-M68 Disorders of synovium and tendon	0.782	0.218	0.000
B34.4 Papovirus infection, unspecified	0.781	0.219	0.000
E11 Non-insulin-dependent diabetes mellitus	0.780	0.220	0.000
M14 Arthropathies in other diseases classified elsewhere	0.780	0.220	0.000
H33 Retinal detachments and breaks	0.778	0.222	0.000
M12 Other specific arthropathies	0.774	0.226	0.000
E24 Cushing's syndrome	0.772	0.228	0.000
E31 Polyglandular dysfunction	0.770	0.230	0.000
E40-E46 Malnutrition	0.769	0.231	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.764	0.236	0.000
E14.5 With peripheral circulatory complications	0.763	0.236	0.000
H33.3 Retinal breaks without detachment	0.763	0.237	0.000
J33.1 Polypoid sinus degeneration	0.761	0.239	0.000
H61 Other disorders of external ear	0.760	0.240	0.000
B35.1 Tinea unguium	0.760	0.240	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.759	0.241	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.759	0.241	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.759	0.241	0.000
E13 Other specified diabetes mellitus	0.757	0.243	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.756	0.244	0.000
B37.4 Candidiasis of other urogenital sites	0.754	0.246	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.753	0.247	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.752	0.248	0.000
D55-D59 Haemolytic anaemias	0.746	0.254	0.000
H30 Chorioretinal inflammation	0.746	0.254	0.000
L40.1 Generalised pustular psoriasis	0.000	0.255	0.745
M86 Osteomyelitis	0.742	0.258	0.000
M06.34 Rheumatoid nodule (Hand)	0.740	0.260	0.000
D69 Purpura and other haemorrhagic conditions	0.739	0.261	0.000
K75.0 Abscess of liver	0.737	0.263	0.000
L40.8 Other psoriasis	0.000	0.263	0.737
B36 Other superficial mycoses	0.736	0.264	0.000
E11.1 With ketoacidosis	0.730	0.270	0.000
M35.7 Hypermobility syndrome	0.729	0.271	0.000
H90-H95 Other disorders of ear	0.726	0.274	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.725	0.275	0.000
M10.0 Idiopathic gout	0.724	0.276	0.000
E06 Thyroiditis	0.723	0.277	0.000
M70-M79 Other soft tissue disorders	0.723	0.277	0.000
H34.1 Central retinal artery occlusion	0.723	0.277	0.000
E03.8 Other specified hypothyroidism	0.723	0.277	0.000
J45.1 Nonallergic asthma	0.721	0.279	0.000
M34.0 Progressive systemic sclerosis	0.718	0.282	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
L40.4 Guttate psoriasis	0.000	0.283	0.716
L40.2 Acrodermatitis continua	0.000	0.283	0.716
M09 Juvenile arthritis in diseases classified elsewhere	0.716	0.284	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.715	0.285	0.000
E32 Diseases of thymus	0.715	0.285	0.000
E30 Disorders of puberty, not elsewhere classified	0.715	0.285	0.000
B25.9 Cytomegaloviral disease, unspecified	0.715	0.285	0.000
H90 Conductive and sensorineural hearing loss	0.714	0.286	0.000
E25 Adrenogenital disorders	0.713	0.287	0.000
D64.4 Congenital dyserythropoietic anaemia	0.713	0.287	0.000
D64.3 Other sideroblastic anaemias	0.713	0.287	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.713	0.287	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.713	0.287	0.000
D64.0 Hereditary sideroblastic anaemia	0.713	0.287	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.713	0.287	0.000
E27.5 Adrenomedullary hyperfunction	0.713	0.287	0.000
E27.0 Other adrenocortical overactivity	0.713	0.287	0.000
K90.3 Pancreatic steatorrhoea	0.713	0.287	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.713	0.287	0.000
K90.1 Tropical sprue	0.713	0.287	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.712	0.288	0.000
E15 Nondiabetic hypoglycaemic coma	0.712	0.288	0.000
M08 Juvenile arthritis	0.711	0.289	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.710	0.290	0.000
M11 Other crystal arthropathies	0.709	0.290	0.000
B37.8 Candidiasis of other sites	0.709	0.291	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.708	0.292	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.708	0.292	0.000
E16.4 Abnormal secretion of gastrin	0.708	0.292	0.000
E16.3 Increased secretion of glucagon	0.708	0.292	0.000
E28.3 Primary ovarian failure	0.708	0.292	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.707	0.293	0.000
M05.2 Rheumatoid vasculitis	0.707	0.293	0.000
M05.1 Rheumatoid lung disease	0.707	0.293	0.000
M05.0 Felty's syndrome	0.707	0.293	0.000
M10.9 Gout, unspecified	0.706	0.294	0.000
H90.2 Conductive hearing loss, unspecified	0.706	0.294	0.000
H34.8 Other retinal vascular occlusions	0.705	0.295	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.705	0.295	0.000
A75-A79 Rickettsioses	0.705	0.295	0.000
A70-A74 Other diseases caused by chlamydiae	0.705	0.295	0.000
A20-A28 Certain zoonotic bacterial diseases	0.705	0.295	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.705	0.295	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.704	0.296	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.704	0.296	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.703	0.297	0.000
K75.2 Nonspecific reactive hepatitis	0.703	0.297	0.000
K75.1 Phlebitis of portal vein	0.703	0.297	0.000
B30 Viral conjunctivitis	0.702	0.297	0.000
B26 Mumps	0.702	0.297	0.000
K77 Liver disorders in diseases classified elsewhere	0.702	0.297	0.000
E16.1 Other hypoglycaemia	0.702	0.298	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.702	0.298	0.000
L40.3 Pustulosis palmaris et plantaris	0.000	0.300	0.699
B34.3 Parvovirus infection, unspecified	0.699	0.301	0.000
B34.2 Coronavirus infection, unspecified	0.699	0.301	0.000
B34.1 Enterovirus infection, unspecified	0.699	0.301	0.000
B34.0 Adenovirus infection, unspecified	0.699	0.301	0.000
B37.1 Pulmonary candidiasis	0.699	0.301	0.000
H31 Other disorders of choroid	0.699	0.301	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.697	0.303	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.697	0.303	0.000
E07.8 Other specified disorders of thyroid	0.697	0.303	0.000
M06.4 Inflammatory polyarthropathy	0.697	0.303	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.696	0.303	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.696	0.303	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.696	0.303	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.696	0.303	0.000
K72 Hepatic failure, not elsewhere classified	0.694	0.306	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.693	0.306	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.693	0.306	0.000
M35.5 Multifocal fibrosclerosis	0.693	0.306	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.693	0.306	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.693	0.307	0.000
B48 Other mycoses, not elsewhere classified	0.692	0.308	0.000
B47 Mycetoma	0.692	0.308	0.000
B46 Zygomycosis	0.692	0.308	0.000
B45 Cryptococcosis	0.692	0.308	0.000
B43 Chromomycosis and phaeomycotic abscess	0.692	0.308	0.000
B42 Sporotrichosis	0.692	0.308	0.000
B41 Paracoccidioidomycosis	0.692	0.308	0.000
B40 Blastomycosis	0.692	0.308	0.000
B39 Histoplasmosis	0.692	0.308	0.000
B38 Coccidioidomycosis	0.692	0.308	0.000
J30-J39 Other diseases of upper respiratory tract	0.692	0.308	0.000
A30-A49 Other bacterial diseases	0.691	0.309	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.689	0.310	0.000
M88 Paget's disease of bone [osteitis deformans]	0.689	0.311	0.000
J45.8 Mixed asthma	0.689	0.311	0.000
M06.8 Other specified rheumatoid arthritis	0.685	0.315	0.000
M10.94 Gout, unspecified (Hand)	0.684	0.316	0.000
A52 Late syphilis	0.683	0.317	0.000
D64.8 Other specified anaemias	0.683	0.317	0.000
H61.8 Other specified disorders of external ear	0.683	0.317	0.000
B37.7 Candidal septicaemia	0.682	0.318	0.000
J85 Abscess of lung and mediastinum	0.680	0.320	0.000
E27.2 Addisonian crisis	0.679	0.321	0.000
M35.2 Behcet's disease	0.678	0.322	0.000
M30 Polyarteritis nodosa and related conditions	0.678	0.322	0.000
K71 Toxic liver disease	0.678	0.322	0.000
M66 Spontaneous rupture of synovium and tendon	0.677	0.323	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.675	0.325	0.000
D50-D53 Nutritional anaemias	0.674	0.326	0.000
H61.3 Acquired stenosis of external ear canal	0.674	0.326	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.673	0.327	0.000
J33.8 Other polyp of sinus	0.671	0.329	0.000
B37.6 Candidal endocarditis	0.670	0.330	0.000
B37.5 Candidal meningitis	0.670	0.330	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.669	0.331	0.000
D69.0 Allergic purpura	0.668	0.332	0.000
E05.8 Other thyrotoxicosis	0.666	0.334	0.000
H61.0 Perichondritis of external ear	0.666	0.334	0.000
E20.9 Hypoparathyroidism, unspecified	0.665	0.335	0.000
E11.3 With ophthalmic complications	0.663	0.337	0.000
E23.6 Other disorders of pituitary gland	0.661	0.339	0.000
D61.9 Aplastic anaemia, unspecified	0.660	0.340	0.000
M32.8 Other forms of systemic lupus erythematosus	0.659	0.341	0.000
M67 Other disorders of synovium and tendon	0.658	0.342	0.000
D61.1 Drug-induced aplastic anaemia	0.657	0.343	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.656	0.344	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.653	0.346	0.000
E11.5 With peripheral circulatory complications	0.653	0.347	0.000
D80 Immunodeficiency with predominantly antibody defects	0.652	0.348	0.000
H33.4 Traction detachment of retina	0.647	0.353	0.000
H30.9 Chorioretinal inflammation, unspecified	0.647	0.353	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.646	0.353	0.000
B35.6 Tinea cruris	0.645	0.355	0.000
E11.0 With coma	0.644	0.356	0.000
B33.2 Viral carditis	0.644	0.356	0.000
A41 Other septicaemia	0.643	0.357	0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.640	0.360	0.000
B44.1 Other pulmonary aspergillosis	0.640	0.360	0.000
M12.5 Traumatic arthropathy	0.640	0.360	0.000
H43-H45 Disorders of vitreous body and globe	0.639	0.361	0.000
B37.2 Candidiasis of skin and nail	0.638	0.362	0.000
H33.1 Retinoschisis and retinal cysts	0.638	0.362	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.637	0.363	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.634	0.366	0.000
E24.2 Drug-induced Cushing's syndrome	0.633	0.367	0.000
A65-A69 Other spirochaetal diseases	0.633	0.367	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.013	0.368	0.619
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed	0.631	0.369	0.000
M33 Dermatopolymyositis	0.630	0.370	0.000
M86.9 Osteomyelitis, unspecified	0.630	0.370	0.000
D84 Other immunodeficiencies	0.629	0.371	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.628	0.372	0.000
E23.1 Drug-induced hypopituitarism	0.628	0.372	0.000
D69.6 Thrombocytopenia, unspecified	0.628	0.372	0.000
M35.8 Other specified systemic involvement of connective tissue	0.627	0.373	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.626	0.374	0.000
M06.38 Rheumatoid nodule (Other)	0.626	0.374	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.626	0.374	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.626	0.374	0.000
M06.33 Rheumatoid nodule (Forearm)	0.626	0.374	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.626	0.374	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.014	0.375	0.612
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.014	0.375	0.612
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.014	0.375	0.612
M45.X4 Ankylosing spondylitis (Thoracic region)	0.014	0.375	0.612
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.014	0.375	0.612
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.014	0.375	0.612
H36.8 Other retinal disorders in diseases classified elsewhere	0.624	0.376	0.000
E29 Testicular dysfunction	0.624	0.376	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.622	0.377	0.000
M10.4 Other secondary gout	0.622	0.378	0.000
M10.3 Gout due to impairment of renal function	0.622	0.378	0.000
M10.2 Drug-induced gout	0.622	0.378	0.000
M10.1 Lead-induced gout	0.622	0.378	0.000
B25.8 Other cytomegaloviral diseases	0.621	0.379	0.000
D59 Acquired haemolytic anaemia	0.620	0.380	0.000
E22.1 Hyperprolactinaemia	0.616	0.384	0.000
M75 Shoulder lesions	0.615	0.385	0.000
B25.0 Cytomegaloviral pneumonitis	0.615	0.385	0.000
D69.4 Other primary thrombocytopenia	0.614	0.386	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.614	0.386	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.614	0.386	0.000
M67.1 Other contracture of tendon (sheath)	0.614	0.386	0.000
H61.1 Non-infective disorders of pinna	0.613	0.387	0.000
D69.2 Other nonthrombocytopenic purpura	0.612	0.388	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.611	0.389	0.000
M76 Enthesopathies of lower limb, excluding foot	0.611	0.389	0.000
J85.1 Abscess of lung with pneumonia	0.610	0.390	0.000
H90.5 Sensorineural hearing loss, unspecified	0.608	0.391	0.000
B99-B99 Other infectious diseases	0.608	0.392	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.607	0.393	0.000
A59 Trichomoniasis	0.607	0.393	0.000
A56 Other sexually transmitted chlamydial diseases	0.607	0.393	0.000
A54 Gonococcal infection	0.607	0.393	0.000
A53 Other and unspecified syphilis	0.607	0.393	0.000
A51 Early syphilis	0.607	0.393	0.000
A50 Congenital syphilis	0.607	0.393	0.000
A64 Unspecified sexually transmitted disease	0.607	0.393	0.000
A58 Granuloma inguinale	0.607	0.393	0.000
A57 Chancroid	0.607	0.393	0.000
A55 Chlamydial lymphogranuloma (venereum)	0.607	0.393	0.000
E31.0 Autoimmune polyglandular failure	0.607	0.393	0.000
A60 Anogenital herpesviral [herpes simplex] infections	0.607	0.393	0.000
J85.2 Abscess of lung without pneumonia	0.606	0.394	0.000
M00-M03 Infectious arthropathies	0.606	0.394	0.000
D83 Common variable immunodeficiency	0.606	0.394	0.000
B35.9 Dermatophytosis, unspecified	0.606	0.394	0.000
B35.8 Other dermatophytoses	0.606	0.394	0.000
B35.5 Tinea imbricata	0.606	0.394	0.000
B35.4 Tinea corporis	0.606	0.394	0.000
B35.2 Tinea manuum	0.606	0.394	0.000
B35.0 Tinea barbae and tinea capitis	0.606	0.394	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.605	0.395	0.000
D50 Iron deficiency anaemia	0.604	0.396	0.000
H34.0 Transient retinal artery occlusion	0.604	0.396	0.000
E46 Unspecified protein-energy malnutrition	0.604	0.396	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.603	0.397	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.603	0.397	0.000
E22.8 Other hyperfunction of pituitary gland	0.603	0.397	0.000
M14.2 Diabetic arthropathy	0.603	0.397	0.000
E23.7 Disorder of pituitary gland, unspecified	0.603	0.397	0.000
A63.0 Anogenital (venereal) warts	0.602	0.398	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.602	0.398	0.000
A18 Tuberculosis of other organs	0.602	0.398	0.000
M10.96 Gout, unspecified (Lower leg)	0.602	0.398	0.000
B25.2 Cytomegaloviral pancreatitis	0.599	0.400	0.000
B25.1 Cytomegaloviral hepatitis	0.599	0.400	0.000
M75.0 Adhesive capsulitis of shoulder	0.599	0.401	0.000
M86.1 Other acute osteomyelitis	0.597	0.403	0.000
E14.4 With neurological complications	0.596	0.404	0.000
M13 Other arthritis	0.595	0.405	0.000
B65-B83 Helminthiases	0.594	0.406	0.000
E06.3 Autoimmune thyroiditis	0.593	0.407	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.592	0.408	0.000
D69.8 Other specified haemorrhagic conditions	0.591	0.409	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.589	0.411	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.589	0.411	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.589	0.411	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.589	0.411	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.589	0.411	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.589	0.411	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.589	0.411	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.589	0.411	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.589	0.411	0.000
H80-H83 Diseases of inner ear	0.586	0.414	0.000
M87 Osteonecrosis	0.586	0.414	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.585	0.414	0.000
M10.04 Idiopathic gout (Hand)	0.584	0.416	0.000
B33.0 Epidemic myalgia	0.584	0.416	0.000
B44.9 Aspergillosis, unspecified	0.584	0.416	0.000
H43 Disorders of vitreous body	0.583	0.417	0.000
A19 Miliary tuberculosis	0.582	0.418	0.000
A17 Tuberculosis of nervous system	0.582	0.418	0.000
E13.9 Without complications	0.581	0.419	0.000
D61.8 Other specified aplastic anaemias	0.579	0.420	0.000
D61.3 Idiopathic aplastic anaemia	0.579	0.420	0.000
D61.2 Aplastic anaemia due to other external agents	0.579	0.420	0.000
H31.1 Choroidal degeneration	0.579	0.421	0.000
D60.8 Other acquired pure red cell aplasias	0.579	0.421	0.000
D60.1 Transient acquired pure red cell aplasia	0.579	0.421	0.000
D60.0 Chronic acquired pure red cell aplasia	0.579	0.421	0.000
K72.0 Acute and subacute hepatic failure	0.578	0.422	0.000
K74 Fibrosis and cirrhosis of liver	0.578	0.422	0.000
J46 Status asthmaticus	0.578	0.422	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.577	0.423	0.000
H34.9 Retinal vascular occlusion, unspecified	0.577	0.423	0.000
E20.8 Other hypoparathyroidism	0.576	0.424	0.000
E20.1 Pseudohypoparathyroidism	0.576	0.424	0.000
E20.0 Idiopathic hypoparathyroidism	0.576	0.424	0.000
A80-A89 Viral infections of the central nervous system	0.576	0.424	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.576	0.424	0.000
B37.0 Candidal stomatitis	0.576	0.424	0.000
J41 Simple and mucopurulent chronic bronchitis	0.575	0.425	0.000
D50.9 Iron deficiency anaemia, unspecified	0.575	0.425	0.000
B15-B19 Viral hepatitis	0.573	0.427	0.000
M66.3 Spontaneous rupture of flexor tendons	0.572	0.428	0.000
D81 Combined immunodeficiencies	0.572	0.428	0.000
B36.9 Superficial mycosis, unspecified	0.571	0.429	0.000
E28.9 Ovarian dysfunction, unspecified	0.570	0.430	0.000
E28.8 Other ovarian dysfunction	0.570	0.430	0.000
E28.1 Androgen excess	0.570	0.430	0.000
E28.0 Oestrogen excess	0.570	0.430	0.000
D69.5 Secondary thrombocytopenia	0.569	0.431	0.000
B34.8 Other viral infections of unspecified site	0.569	0.431	0.000
E07.1 Dyshormogenetic goitre	0.568	0.432	0.000
E07.0 Hypersecretion of calcitonin	0.568	0.432	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.567	0.433	0.000
B27 Infectious mononucleosis	0.566	0.433	0.000
D82 Immunodeficiency associated with other major defects	0.566	0.434	0.000
A52.1 Symptomatic neurosyphilis	0.566	0.434	0.000
M06.0 Seronegative rheumatoid arthritis	0.566	0.434	0.000
B33.4 Hantavirus (cardio-)pulmonary syndrome [HPS] [HCPS]	0.565	0.435	0.000
B33.3 Retrovirus infections, not elsewhere classified	0.565	0.435	0.000
B33.1 Ross River disease	0.565	0.435	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.564	0.436	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.564	0.436	0.000
E24.0 Pituitary-dependent Cushing's disease	0.563	0.437	0.000
H43.1 Vitreous haemorrhage	0.562	0.438	0.000
B44.8 Other forms of aspergillosis	0.562	0.438	0.000
B44.7 Disseminated aspergillosis	0.562	0.438	0.000
B44.2 Tonsillar aspergillosis	0.562	0.438	0.000
B44.0 Invasive pulmonary aspergillosis	0.562	0.438	0.000
M88.9 Paget's disease of bone, unspecified	0.562	0.438	0.000
M86.8 Other osteomyelitis	0.562	0.438	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.561	0.439	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.560	0.440	0.000
E11.7 With multiple complications	0.560	0.440	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.559	0.441	0.000
M14.4 Arthropathy in amyloidosis	0.559	0.441	0.000
M14.3 Lipoid dermatoarthritis	0.559	0.441	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.559	0.441	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.559	0.441	0.000
H30.2 Posterior cyclitis	0.559	0.441	0.000
B33.8 Other specified viral diseases	0.557	0.443	0.000
M12.4 Intermittent hydrarthrosis	0.555	0.445	0.000
M12.1 Kaschin-Beck disease	0.555	0.445	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.555	0.445	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations