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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2050188
log Bayes Factor = 209.683
Chromosome 6   position 32,339,897  (GRCh37) Explore rs2050188 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.001 0.999
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.001 0.999
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.003 0.997
J32 Chronic sinusitis
0.000 0.004 0.996
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.004 0.996
E10.5 With peripheral circulatory complications
0.000 0.007 0.993
J32.9 Chronic sinusitis, unspecified
0.000 0.007 0.993
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.009 0.991
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.011 0.989
Chapter VIII Diseases of the ear and mastoid process
0.000 0.011 0.989
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.012 0.988
E10.2 With renal complications
0.000 0.013 0.987
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.014 0.986
E14.9 Without complications
0.000 0.016 0.984
M06.3 Rheumatoid nodule
0.000 0.018 0.982
J33.8 Other polyp of sinus
0.000 0.018 0.982
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.021 0.979
L43 Lichen planus
0.000 0.024 0.976
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.025 0.975
H90-H95 Other disorders of ear
0.000 0.025 0.975
J43 Emphysema
0.000 0.028 0.972
J46 Status asthmaticus
0.000 0.028 0.972
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.033 0.967
H91 Other hearing loss
0.000 0.033 0.967
Chapter II Neoplasms
0.000 0.034 0.966
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.037 0.963
G35-G37 Demyelinating diseases of the central nervous system
0.961 0.038 0.001
E11.3 With ophthalmic complications
0.000 0.039 0.961
J44 Other chronic obstructive pulmonary disease
0.000 0.040 0.960
H91.9 Hearing loss, unspecified
0.000 0.040 0.960
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.041 0.959
L43.9 Lichen planus, unspecified
0.000 0.041 0.959
H60-H62 Diseases of external ear
0.000 0.042 0.958
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.042 0.958
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.042 0.958
C83.3 Large cell (diffuse)
0.000 0.043 0.957
E11.5 With peripheral circulatory complications
0.000 0.045 0.955
G37 Other demyelinating diseases of central nervous system
0.953 0.047 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.049 0.951
C85.1 B-cell lymphoma, unspecified
0.000 0.052 0.948
G37.9 Demyelinating disease of central nervous system, unspecified
0.939 0.061 0.000
C09 Malignant neoplasm of tonsil
0.000 0.061 0.939
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.062 0.938
E10.6 With other specified complications
0.000 0.064 0.936
H36 Retinal disorders in diseases classified elsewhere
0.000 0.066 0.934
J43.9 Emphysema, unspecified
0.000 0.070 0.930
J33.0 Polyp of nasal cavity
0.000 0.072 0.928
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.073 0.927
M07 Psoriatic and enteropathic arthropathies
0.000 0.073 0.927
M06.34 Rheumatoid nodule (Hand)
0.000 0.073 0.927
C09.9 Tonsil, unspecified
0.000 0.077 0.923
E10.0 With coma
0.000 0.080 0.920
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.082 0.918
E11.2 With renal complications
0.000 0.082 0.918
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.082 0.918
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.084 0.916
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.089 0.911
C02.9 Tongue, unspecified
0.000 0.090 0.910
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.092 0.908
E10.8 With unspecified complications
0.000 0.097 0.903
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.106 0.894
C02.1 Border of tongue
0.000 0.109 0.891
E11.1 With ketoacidosis
0.000 0.110 0.890
H60 Otitis externa
0.000 0.112 0.888
H30-H36 Disorders of choroid and retina
0.000 0.113 0.887
Chapter VII Diseases of the eye and adnexa
0.000 0.116 0.884
M06.4 Inflammatory polyarthropathy
0.000 0.116 0.884
M07.3 Other psoriatic arthropathies
0.000 0.121 0.879
H61 Other disorders of external ear
0.000 0.125 0.875
E06 Thyroiditis
0.000 0.126 0.874
E13 Other specified diabetes mellitus
0.000 0.130 0.870
L50-L54 Urticaria and erythema
0.000 0.145 0.855
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.147 0.853
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.147 0.853
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.154 0.846
G37.8 Other specified demyelinating diseases of central nervous system
0.842 0.158 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.164 0.836
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.167 0.833
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.170 0.830
E40-E46 Malnutrition
0.000 0.170 0.830
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.171 0.829
J32.4 Chronic pansinusitis
0.000 0.173 0.827
C91 Lymphoid leukaemia
0.000 0.175 0.825
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.177 0.823
C82.0 Small cleaved cell, follicular
0.000 0.178 0.822
C12 Malignant neoplasm of pyriform sinus
0.000 0.181 0.819
M14 Arthropathies in other diseases classified elsewhere
0.000 0.183 0.817
E06.3 Autoimmune thyroiditis
0.000 0.184 0.816
E05.9 Thyrotoxicosis, unspecified
0.000 0.185 0.815
H60.1 Cellulitis of external ear
0.000 0.187 0.813
J32.2 Chronic ethmoidal sinusitis
0.000 0.188 0.812
H40-H42 Glaucoma
0.000 0.188 0.812
M65-M68 Disorders of synovium and tendon
0.000 0.188 0.812
D64.9 Anaemia, unspecified
0.000 0.190 0.810
C95 Leukaemia of unspecified cell type
0.000 0.190 0.810
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.191 0.809
H91.1 Presbycusis
0.000 0.192 0.808
M35.3 Polymyalgia rheumatica
0.000 0.193 0.807
E11.4 With neurological complications
0.000 0.196 0.804
E11.8 With unspecified complications
0.000 0.197 0.803
L40.0 Psoriasis vulgaris
0.000 0.197 0.803
J43.2 Centrilobular emphysema
0.000 0.199 0.801
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.200 0.800
C82.2 Large cell, follicular
0.000 0.201 0.799
E14.5 With peripheral circulatory complications
0.000 0.201 0.799
C45 Mesothelioma
0.000 0.202 0.798
E14.4 With neurological complications
0.000 0.207 0.793
E11.0 With coma
0.000 0.209 0.791
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.210 0.790
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.216 0.784
L80 Vitiligo
0.000 0.218 0.782
E14.8 With unspecified complications
0.000 0.218 0.782
M35 Other systemic involvement of connective tissue
0.000 0.221 0.779
M20-M25 Other joint disorders
0.000 0.223 0.777
J37 Chronic laryngitis and laryngotracheitis
0.000 0.223 0.777
E13.9 Without complications
0.000 0.223 0.777
E16.1 Other hypoglycaemia
0.000 0.229 0.771
J45.1 Nonallergic asthma
0.000 0.231 0.769
C02.4 Lingual tonsil
0.000 0.234 0.766
L51 Erythema multiforme
0.000 0.234 0.766
J43.8 Other emphysema
0.000 0.235 0.765
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.237 0.763
H40 Glaucoma
0.000 0.239 0.761
H43-H45 Disorders of vitreous body and globe
0.000 0.240 0.760
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.240 0.760
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.241 0.759
C10 Malignant neoplasm of oropharynx
0.000 0.241 0.759
D64 Other anaemias
0.003 0.241 0.756
E03.8 Other specified hypothyroidism
0.000 0.242 0.758
H40.9 Glaucoma, unspecified
0.000 0.242 0.758
C11 Malignant neoplasm of nasopharynx
0.000 0.243 0.757
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.245 0.754
M45-M49 Spondylopathies
0.000 0.246 0.754
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.014 0.246 0.740
L10-L14 Bullous disorders
0.000 0.247 0.753
H61.8 Other specified disorders of external ear
0.000 0.248 0.752
C13 Malignant neoplasm of hypopharynx
0.000 0.250 0.749
L52 Erythema nodosum
0.000 0.252 0.748
C83.1 Small cleaved cell (diffuse)
0.000 0.254 0.746
J33.1 Polypoid sinus degeneration
0.000 0.254 0.746
M65 Synovitis and tenosynovitis
0.000 0.255 0.745
H61.3 Acquired stenosis of external ear canal
0.000 0.256 0.744
D60-D64 Aplastic and other anaemias
0.005 0.257 0.738
K90 Intestinal malabsorption
0.000 0.258 0.742
L89 Decubitus ulcer
0.000 0.259 0.741
L94 Other localised connective tissue disorders
0.000 0.263 0.737
J86 Pyothorax
0.000 0.265 0.735
H90 Conductive and sensorineural hearing loss
0.000 0.266 0.734
C02.2 Ventral surface of tongue
0.000 0.266 0.734
H30 Chorioretinal inflammation
0.000 0.266 0.734
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.267 0.733
M45 Ankylosing spondylitis
0.000 0.267 0.733
C04 Malignant neoplasm of floor of mouth
0.000 0.270 0.730
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.270 0.729
C84.5 Other and unspecified T-cell lymphomas
0.000 0.271 0.729
C82.4 Follicular lymphoma grade IIIb
0.000 0.271 0.729
E07 Other disorders of thyroid
0.000 0.271 0.729
C03 Malignant neoplasm of gum
0.000 0.272 0.728
H91.2 Sudden idiopathic hearing loss
0.000 0.274 0.726
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.279 0.721
H60.5 Acute otitis externa, non-infective
0.000 0.280 0.720
C82.3 Follicular lymphoma grade IIIa
0.000 0.281 0.719
J35 Chronic diseases of tonsils and adenoids
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.284 0.716
H60.4 Cholesteatoma of external ear
0.000 0.284 0.716
L85 Other epidermal thickening
0.000 0.287 0.713
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.287 0.712
C82.6 Cutaneous follicle centre lymphoma
0.000 0.290 0.710
C82.5 Diffuse follicle centre lymphoma
0.000 0.290 0.710
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.291 0.709
H61.1 Non-infective disorders of pinna
0.000 0.291 0.709
J45.8 Mixed asthma
0.000 0.292 0.708
C95.9 Leukaemia, unspecified
0.000 0.292 0.708
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.292 0.708
E46 Unspecified protein-energy malnutrition
0.000 0.292 0.707
E03.1 Congenital hypothyroidism without goitre
0.000 0.293 0.707
M31 Other necrotising vasculopathies
0.000 0.294 0.706
H43 Disorders of vitreous body
0.000 0.294 0.706
C91.1 Chronic lymphocytic leukaemia
0.000 0.294 0.706
M06.8 Other specified rheumatoid arthritis
0.000 0.294 0.706
J32.8 Other chronic sinusitis
0.000 0.295 0.705
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.296 0.704
M06.38 Rheumatoid nodule (Other)
0.000 0.296 0.704
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.296 0.704
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.296 0.704
M06.33 Rheumatoid nodule (Forearm)
0.000 0.296 0.704
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.296 0.704
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.296 0.704
M14.6 Neuropathic arthropathy
0.000 0.296 0.704
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.297 0.703
L40.1 Generalised pustular psoriasis
0.000 0.297 0.703
E11.6 With other specified complications
0.000 0.300 0.700
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.300 0.700
L43.3 Subacute (active) lichen planus
0.000 0.300 0.700
L43.2 Lichenoid drug reaction
0.000 0.300 0.700
L43.1 Bullous lichen planus
0.000 0.300 0.700
L43.0 Hypertrophic lichen planus
0.000 0.300 0.700
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.300 0.700
C85.0 Lymphosarcoma
0.000 0.301 0.699
H94 Other disorders of ear in diseases classified elsewhere
0.000 0.301 0.699
J43.1 Panlobular emphysema
0.000 0.303 0.697
J43.0 MacLeod's syndrome
0.000 0.303 0.697
E14.1 With ketoacidosis
0.000 0.303 0.697
M31.6 Other giant cell arteritis
0.000 0.304 0.696
C45.9 Mesothelioma, unspecified
0.000 0.304 0.696
L43.8 Other lichen planus
0.000 0.304 0.696
L85.8 Other specified epidermal thickening
0.000 0.305 0.695
J38.3 Other diseases of vocal cords
0.000 0.305 0.695
H91.0 Ototoxic hearing loss
0.000 0.307 0.693
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.000 0.307 0.693
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.691 0.309 0.000
C45.7 Mesothelioma of other sites
0.000 0.309 0.691
L40.3 Pustulosis palmaris et plantaris
0.000 0.309 0.691
C45.0 Mesothelioma of pleura
0.000 0.309 0.691
H92 Otalgia and effusion of ear
0.000 0.310 0.690
L40.4 Guttate psoriasis
0.000 0.312 0.687
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.313 0.687
C83.6 Undifferentiated (diffuse)
0.000 0.313 0.687
C83.5 Lymphoblastic (diffuse)
0.000 0.313 0.687
C83.4 Immunoblastic (diffuse)
0.000 0.313 0.687
C83.2 Mixed small and large cell (diffuse)
0.000 0.313 0.687
C02.8 Overlapping lesion of tongue
0.000 0.313 0.687
C02.3 Anterior two-thirds of tongue, part unspecified
0.000 0.313 0.687
C02.0 Dorsal surface of tongue
0.000 0.313 0.687
J38.0 Paralysis of vocal cords and larynx
0.000 0.313 0.687
K90-K93 Other diseases of the digestive system
0.000 0.314 0.686
H60.3 Other infective otitis externa
0.000 0.314 0.686
L92.0 Granuloma annulare
0.000 0.315 0.685
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.316 0.684
G37.5 Concentric sclerosis [Balo]
0.683 0.316 0.000
G37.4 Subacute necrotising myelitis
0.683 0.316 0.000
G37.2 Central pontine myelinolysis
0.683 0.316 0.000
G37.1 Central demyelination of corpus callosum
0.683 0.316 0.000
G37.0 Diffuse sclerosis
0.683 0.316 0.000
M12 Other specific arthropathies
0.000 0.318 0.682
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.318 0.682
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.318 0.682
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.318 0.682
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.318 0.682
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.318 0.682
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.318 0.682
C06 Malignant neoplasm of other and unspecified parts of mouth
0.000 0.319 0.681
H40.5 Glaucoma secondary to other eye disorders
0.000 0.320 0.680
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.321 0.679
H90.5 Sensorineural hearing loss, unspecified
0.000 0.326 0.674
C09.8 Overlapping lesion of tonsil
0.000 0.327 0.673
C09.0 Tonsillar fossa
0.000 0.327 0.673
C05 Malignant neoplasm of palate
0.000 0.328 0.672
C84.0 Mycosis fungoides
0.000 0.329 0.671
H25-H28 Disorders of lens
0.000 0.329 0.671
J41 Simple and mucopurulent chronic bronchitis
0.000 0.330 0.670
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.330 0.670
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.332 0.668
H43.1 Vitreous haemorrhage
0.000 0.334 0.666
M07.5 Arthropathy in ulcerative colitis
0.000 0.335 0.665
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.335 0.665
M07.2 Psoriatic spondylitis
0.000 0.335 0.665
M07.1 Arthritis mutilans
0.000 0.335 0.665
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.335 0.665
C07 Malignant neoplasm of parotid gland
0.000 0.335 0.665
G36 Other acute disseminated demyelination
0.664 0.336 0.001
Chapter XI Diseases of the digestive system
0.000 0.337 0.663
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.338 0.662
H61.2 Impacted cerumen
0.000 0.338 0.662
L89.1 Stage II decubitus ulcer
0.000 0.341 0.659
C91.5 Adult T-cell leukaemia
0.000 0.341 0.658
L94.2 Calcinosis cutis
0.000 0.342 0.658
E05.5 Thyroid crisis or storm
0.000 0.342 0.658
E05.4 Thyrotoxicosis factitia
0.000 0.342 0.658
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.342 0.658
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.342 0.658
L51.9 Erythema multiforme, unspecified
0.000 0.342 0.658
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.342 0.658
M10 Gout
0.000 0.343 0.656
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.345 0.655
H34 Retinal vascular occlusions
0.000 0.345 0.655
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.347 0.653
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.350 0.650
J86.0 Pyothorax with fistula
0.000 0.350 0.650
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.353 0.647
C91.9 Lymphoid leukaemia, unspecified
0.000 0.356 0.644
J32.0 Chronic maxillary sinusitis
0.000 0.357 0.643
M07.6 Other enteropathic arthropathies
0.000 0.357 0.643
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.357 0.643
H60.0 Abscess of external ear
0.000 0.360 0.640
H61.0 Perichondritis of external ear
0.000 0.361 0.639
H60.2 Malignant otitis externa
0.000 0.362 0.638
L51.1 Bullous erythema multiforme
0.000 0.363 0.637
M05.2 Rheumatoid vasculitis
0.000 0.363 0.637
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.364 0.636
J32.3 Chronic sphenoidal sinusitis
0.000 0.364 0.636
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.364 0.636
L84 Corns and callosities
0.000 0.365 0.635
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.366 0.634
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.366 0.634
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.366 0.634
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.366 0.634
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.366 0.634
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.366 0.634
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.366 0.634
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.366 0.634
M07.38 Other psoriatic arthropathies (Other)
0.000 0.369 0.630
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.369 0.630
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.369 0.630
C86 Other specified types of T/NK-cell lymphoma
0.000 0.369 0.630
C94 Other leukaemias of specified cell type
0.000 0.372 0.628
J35.8 Other chronic diseases of tonsils and adenoids
0.000 0.372 0.628
E06.4 Drug-induced thyroiditis
0.000 0.374 0.626
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.374 0.626
E06.0 Acute thyroiditis
0.000 0.374 0.626
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.374 0.626
H93 Other disorders of ear, not elsewhere classified
0.000 0.375 0.625
H40.3 Glaucoma secondary to eye trauma
0.000 0.375 0.625
H30.9 Chorioretinal inflammation, unspecified
0.000 0.376 0.624
C01 Malignant neoplasm of base of tongue
0.000 0.376 0.624
E13.8 With unspecified complications
0.000 0.376 0.624
E13.7 With multiple complications
0.000 0.376 0.624
E13.6 With other specified complications
0.000 0.376 0.624
E13.5 With peripheral circulatory complications
0.000 0.376 0.624
E13.4 With neurological complications
0.000 0.376 0.624
E13.3 With ophthalmic complications
0.000 0.376 0.624
E13.2 With renal complications
0.000 0.376 0.624
E13.1 With ketoacidosis
0.000 0.376 0.624
E13.0 With coma
0.000 0.376 0.624
H91.8 Other specified hearing loss
0.000 0.378 0.622
J32.1 Chronic frontal sinusitis
0.000 0.381 0.619
H92.0 Otalgia
0.000 0.381 0.619
K70-K77 Diseases of liver
0.000 0.382 0.618
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.382 0.618
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.383 0.617
M25.46 Effusion of joint (Lower leg)
0.000 0.383 0.617
J37.0 Chronic laryngitis
0.000 0.383 0.617
M25 Other joint disorders, not elsewhere classified
0.000 0.384 0.616
E06.5 Other chronic thyroiditis
0.000 0.384 0.616
M25.4 Effusion of joint
0.000 0.385 0.615
L54 Erythema in diseases classified elsewhere
0.000 0.387 0.613
D86.0 Sarcoidosis of lung
0.613 0.387 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.387 0.613
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.388 0.612
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.388 0.612
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.388 0.612
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.388 0.612
C84.3 Lymphoepithelioid lymphoma
0.000 0.388 0.612
C84.2 T-zone lymphoma
0.000 0.388 0.612
C84.1 Sezary's diease
0.000 0.388 0.612
C10.9 Oropharynx, unspecified
0.000 0.390 0.610
L13 Other bullous disorders
0.000 0.392 0.608
E05.8 Other thyrotoxicosis
0.000 0.393 0.606
C11.9 Nasopharynx, unspecified
0.000 0.394 0.606
L42 Pityriasis rosea
0.000 0.396 0.604
C84.4 Peripheral T-cell lymphoma
0.000 0.397 0.602
M49 Spondylopathies in diseases classified elsewhere
0.000 0.398 0.602
H60.8 Other otitis externa
0.000 0.399 0.601
H43.3 Other vitreous opacities
0.000 0.400 0.600
H27 Other disorders of lens
0.000 0.401 0.599
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.401 0.599
L87 Transepidermal elimination disorders
0.000 0.401 0.599
L86 Keratoderma in diseases classified elsewhere
0.000 0.401 0.599
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.402 0.598
H91.3 Deaf mutism, not elsewhere classified
0.000 0.404 0.596
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.405 0.595
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.000 0.405 0.595
C46 Kaposi's sarcoma
0.000 0.405 0.595
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.405 0.595
E45 Retarded development following protein-energy malnutrition
0.000 0.405 0.595
E43 Unspecified severe protein-energy malnutrition
0.000 0.405 0.595
E42 Marasmic kwashiorkor
0.000 0.405 0.595
E41 Nutritional marasmus
0.000 0.405 0.595
E40 Kwashiorkor
0.000 0.405 0.595
L89.2 Stage III decubitus ulcer
0.000 0.405 0.595
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.406 0.594
C13.9 Hypopharynx, unspecified
0.000 0.407 0.593
E06.9 Thyroiditis, unspecified
0.000 0.407 0.593
K74 Fibrosis and cirrhosis of liver
0.000 0.408 0.592
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.409 0.591
C91.7 Other lymphoid leukaemia
0.000 0.409 0.591
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.409 0.591
C91.3 Prolymphocytic leukaemia
0.000 0.409 0.591
C91.2 Subacute lymphocytic leukaemia
0.000 0.409 0.591
M35.1 Other overlap syndromes
0.000 0.411 0.589
H40.4 Glaucoma secondary to eye inflammation
0.000 0.411 0.589
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.412 0.588
J35.2 Hypertrophy of adenoids
0.000 0.413 0.587
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.414 0.586
M14.4 Arthropathy in amyloidosis
0.000 0.414 0.586
M14.3 Lipoid dermatoarthritis
0.000 0.414 0.586
M14.2 Diabetic arthropathy
0.000 0.414 0.586
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.414 0.586
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.414 0.586
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.416 0.584
M60-M63 Disorders of muscles
0.000 0.416 0.584
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.416 0.584
C09.1 Tonsillar pillar (anterior) (posterior)
0.000 0.416 0.583
H42 Glaucoma in diseases classified elsewhere
0.000 0.417 0.582
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.418 0.582
C95.0 Acute leukaemia of unspecified cell type
0.000 0.418 0.582
K74.3 Primary biliary cirrhosis
0.000 0.418 0.582
L89.9 Decubitus ulcer and pressure area, unspecified
0.000 0.418 0.582
C95.7 Other leukaemia of unspecified cell type
0.000 0.419 0.581
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.419 0.581
C93 Monocytic leukaemia
0.000 0.420 0.580
M66 Spontaneous rupture of synovium and tendon
0.000 0.420 0.580
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.422 0.577
M00-M03 Infectious arthropathies
0.000 0.425 0.575
C00 Malignant neoplasm of lip
0.000 0.426 0.574
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.426 0.574
L89.0 Stage I decubitus ulcer and pressure area
0.000 0.426 0.574
D86 Sarcoidosis
0.563 0.426 0.010
C45.2 Mesothelioma of pericardium
0.000 0.428 0.572
C45.1 Mesothelioma of peritoneum
0.000 0.428 0.572
H34.2 Other retinal artery occlusions
0.000 0.430 0.570
M65.8 Other synovitis and tenosynovitis
0.000 0.431 0.569
C88 Malignant immunoproliferative diseases
0.000 0.434 0.566
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.434 0.566
K73 Chronic hepatitis, not elsewhere classified
0.000 0.435 0.565
J86.9 Pyothorax without fistula
0.000 0.436 0.564
C91.0 Acute lymphoblastic leukaemia
0.000 0.438 0.562
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.438 0.562
M13 Other arthritis
0.000 0.438 0.562
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.439 0.561
M34 Systemic sclerosis
0.000 0.440 0.560
L94.9 Localised connective tissue disorder, unspecified
0.000 0.440 0.560
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.441 0.558

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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