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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs378088
log Bayes Factor = 61.8023
Chromosome 6   position 32,196,313  (GRCh37) Explore rs378088 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
E16.2 Hypoglycaemia, unspecified
0.000 0.002 0.998
E03 Other hypothyroidism
0.000 0.007 0.993
E03.9 Hypothyroidism, unspecified
0.000 0.008 0.992
M06 Other rheumatoid arthritis
0.000 0.011 0.989
E14 Unspecified diabetes mellitus
0.000 0.012 0.988
H36.0 Diabetic retinopathy
0.000 0.013 0.987
E10.4 With neurological complications
0.000 0.014 0.986
K90.0 Coeliac disease
0.000 0.015 0.985
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.018 0.982
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.021 0.979
E10.2 With renal complications
0.000 0.028 0.972
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.031 0.969
L40.9 Psoriasis, unspecified
0.000 0.032 0.968
E14.3 With ophthalmic complications
0.000 0.039 0.961
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.048 0.952
M06.3 Rheumatoid nodule
0.000 0.056 0.944
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.071 0.929
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.072 0.928
E10.5 With peripheral circulatory complications
0.000 0.079 0.921
E50-E64 Other nutritional deficiencies
0.000 0.090 0.910
E10.0 With coma
0.000 0.091 0.909
E14.9 Without complications
0.000 0.103 0.897
E06 Thyroiditis
0.000 0.119 0.881
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.125 0.875
E04 Other non-toxic goitre
0.000 0.143 0.857
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.154 0.846
M05-M14 Inflammatory polyarthropathies
0.000 0.156 0.844
M05 Seropositive rheumatoid arthritis
0.000 0.161 0.839
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.163 0.837
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.164 0.836
E10.6 With other specified complications
0.000 0.166 0.834
M06.4 Inflammatory polyarthropathy
0.000 0.167 0.833
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.168 0.832
M06.0 Seronegative rheumatoid arthritis
0.000 0.174 0.826
M06.34 Rheumatoid nodule (Hand)
0.000 0.179 0.821
G37 Other demyelinating diseases of central nervous system
0.000 0.185 0.815
E06.3 Autoimmune thyroiditis
0.000 0.187 0.813
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.197 0.803
E53 Deficiency of other B group vitamins
0.000 0.215 0.785
H36 Retinal disorders in diseases classified elsewhere
0.000 0.216 0.784
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.223 0.777
E55 Vitamin D deficiency
0.000 0.229 0.771
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.232 0.768
E07 Other disorders of thyroid
0.000 0.241 0.759
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.241 0.759
E04.0 Non-toxic diffuse goitre
0.000 0.252 0.748
E10.8 With unspecified complications
0.000 0.254 0.746
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.258 0.742
E04.2 Non-toxic multinodular goitre
0.000 0.264 0.736
E14.1 With ketoacidosis
0.000 0.266 0.734
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.267 0.733
E61 Deficiency of other nutrient elements
0.000 0.270 0.730
E14.8 With unspecified complications
0.000 0.277 0.722
E14.4 With neurological complications
0.000 0.280 0.720
L40 Psoriasis
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E03.5 Myxoedema coma
0.000 0.288 0.712
E03.4 Atrophy of thyroid (acquired)
0.000 0.288 0.712
E03.3 Postinfectious hypothyroidism
0.000 0.288 0.712
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.288 0.712
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.288 0.712
M06.8 Other specified rheumatoid arthritis
0.000 0.291 0.709
M06.2 Rheumatoid bursitis
0.000 0.291 0.709
M06.1 Adult-onset Still's disease
0.000 0.291 0.709
E14.7 With multiple complications
0.000 0.292 0.708
E14.6 With other specified complications
0.000 0.292 0.708
E14.5 With peripheral circulatory complications
0.000 0.292 0.708
E14.0 With coma
0.000 0.292 0.708
E40-E46 Malnutrition
0.000 0.292 0.708
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.292 0.708
E05.5 Thyroid crisis or storm
0.000 0.298 0.702
E05.4 Thyrotoxicosis factitia
0.000 0.298 0.702
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.298 0.702
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.298 0.702
E05.9 Thyrotoxicosis, unspecified
0.000 0.299 0.701
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.303 0.697
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.323 0.677
M06.38 Rheumatoid nodule (Other)
0.000 0.323 0.677
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.323 0.677
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.323 0.677
M06.33 Rheumatoid nodule (Forearm)
0.000 0.323 0.677
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.323 0.677
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.323 0.677
E03.1 Congenital hypothyroidism without goitre
0.000 0.326 0.674
E55.9 Vitamin D deficiency, unspecified
0.000 0.328 0.672
E53.9 Vitamin B deficiency, unspecified
0.000 0.330 0.670
E05.8 Other thyrotoxicosis
0.000 0.340 0.660
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.348 0.652
E63 Other nutritional deficiencies
0.000 0.348 0.652
E56 Other vitamin deficiencies
0.000 0.348 0.652
E50 Vitamin A deficiency
0.000 0.348 0.652
E60 Dietary zinc deficiency
0.000 0.348 0.652
E59 Dietary selenium deficiency
0.000 0.348 0.652
E54 Ascorbic acid deficiency
0.000 0.348 0.652
E52 Niacin deficiency [pellagra]
0.000 0.348 0.652
E07.8 Other specified disorders of thyroid
0.000 0.355 0.645
E14.2 Withrenal complications
0.000 0.357 0.643
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.360 0.640
H30-H36 Disorders of choroid and retina
0.000 0.362 0.638
E61.1 Iron deficiency
0.000 0.362 0.638
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.364 0.636
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.368 0.632
E06.5 Other chronic thyroiditis
0.000 0.368 0.632
E06.4 Drug-induced thyroiditis
0.000 0.368 0.632
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.368 0.632
E06.1 Subacute thyroiditis
0.000 0.368 0.632
E06.0 Acute thyroiditis
0.000 0.368 0.632
E70-E90 Metabolic disorders
0.000 0.368 0.632
E51 Thiamine deficiency
0.000 0.370 0.630
G36 Other acute disseminated demyelination
0.000 0.373 0.627
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.381 0.619
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.384 0.616
E04.8 Other specified non-toxic goitre
0.000 0.386 0.614
H33 Retinal detachments and breaks
0.000 0.386 0.614
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.387 0.613
E53.8 Deficiency of other specified B group vitamins
0.000 0.387 0.613
E86 Volume depletion
0.000 0.395 0.605
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.395 0.605
M08 Juvenile arthritis
0.000 0.395 0.605
M05.8 Other seropositive rheumatoid arthritis
0.000 0.399 0.601
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.399 0.601
M05.2 Rheumatoid vasculitis
0.000 0.399 0.601
M05.1 Rheumatoid lung disease
0.000 0.399 0.601
M05.0 Felty's syndrome
0.000 0.399 0.601
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.401 0.599
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.401 0.599
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.401 0.599
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.401 0.599
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.401 0.599
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.401 0.599
H33.3 Retinal breaks without detachment
0.000 0.401 0.599
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.403 0.597
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.403 0.597
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.403 0.597
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.403 0.597
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.403 0.597
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.403 0.597
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.403 0.597
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.403 0.597
E03.8 Other specified hypothyroidism
0.000 0.404 0.596
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.408 0.592
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.408 0.592
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.408 0.592
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.408 0.592
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.408 0.592
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.408 0.592
L40.5 Arthropathic psoriasis
0.000 0.412 0.588
H33.2 Serous retinal detachment
0.000 0.412 0.588
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.415 0.585
G37.5 Concentric sclerosis [Balo]
0.000 0.415 0.584
G37.4 Subacute necrotising myelitis
0.000 0.415 0.584
G37.2 Central pontine myelinolysis
0.000 0.415 0.584
G37.1 Central demyelination of corpus callosum
0.000 0.415 0.584
G37.0 Diffuse sclerosis
0.000 0.415 0.584
E16.1 Other hypoglycaemia
0.000 0.415 0.584
E58 Dietary calcium deficiency
0.000 0.416 0.584
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.419 0.581
M12 Other specific arthropathies
0.000 0.419 0.581
M14 Arthropathies in other diseases classified elsewhere
0.000 0.421 0.579
E06.9 Thyroiditis, unspecified
0.000 0.427 0.573
E73 Lactose intolerance
0.000 0.430 0.570
E53.1 Pyridoxine deficiency
0.000 0.437 0.563
E53.0 Riboflavin deficiency
0.000 0.437 0.563
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.438 0.562
J33.0 Polyp of nasal cavity
0.000 0.441 0.559
L40.0 Psoriasis vulgaris
0.000 0.441 0.559
J33 Nasal polyp
0.000 0.445 0.555
E55.0 Rickets, active
0.000 0.447 0.553
E07.1 Dyshormogenetic goitre
0.000 0.456 0.544
E07.0 Hypersecretion of calcitonin
0.000 0.456 0.544
J30-J39 Other diseases of upper respiratory tract
0.000 0.458 0.542
E04.9 Non-toxic goitre, unspecified
0.000 0.458 0.542
L40-L45 Papulosquamous disorders
0.000 0.460 0.540
K90 Intestinal malabsorption
0.000 0.467 0.533
M10 Gout
0.000 0.467 0.533
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.473 0.527
E73.9 Lactose intolerance, unspecified
0.000 0.474 0.526
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.474 0.525
J32 Chronic sinusitis
0.000 0.476 0.524
E61.9 Deficiency of nutrient element, unspecified
0.000 0.477 0.523
E61.8 Deficiency of other specified nutrient elements
0.000 0.477 0.523
E61.7 Deficiency of multiple nutrient elements
0.000 0.477 0.523
E61.6 Vanadium deficiency
0.000 0.477 0.523
E61.5 Molybdenum deficiency
0.000 0.477 0.523
E61.4 Chromium deficiency
0.000 0.477 0.523
E61.3 Manganese deficiency
0.000 0.477 0.523
E61.0 Copper deficiency
0.000 0.477 0.523
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.480 0.520
E11 Non-insulin-dependent diabetes mellitus
0.000 0.482 0.518
L40.3 Pustulosis palmaris et plantaris
0.000 0.485 0.514
L40.2 Acrodermatitis continua
0.000 0.485 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E88 Other metabolic disorders
0.000 0.488 0.512
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.491 0.508
M06.18 Adult-onset Still's disease (Other)
0.000 0.491 0.508
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.491 0.508
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.491 0.508
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.491 0.508
M06.14 Adult-onset Still's disease (Hand)
0.000 0.491 0.508
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.491 0.508
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.491 0.508
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.491 0.508
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.491 0.508
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.491 0.508
M06.28 Rheumatoid bursitis (Other)
0.000 0.491 0.508
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.491 0.508
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.491 0.508
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.491 0.508
M06.24 Rheumatoid bursitis (Hand)
0.000 0.491 0.508
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.491 0.508
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.491 0.508
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.491 0.508
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.491 0.508
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.491 0.508
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.491 0.508
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.491 0.508
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.491 0.508
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.491 0.508
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.491 0.508
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.491 0.508
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.491 0.508
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.491 0.508
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.491 0.508
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.492 0.508
E45 Retarded development following protein-energy malnutrition
0.000 0.492 0.508
E43 Unspecified severe protein-energy malnutrition
0.000 0.492 0.508
E42 Marasmic kwashiorkor
0.000 0.492 0.508
E41 Nutritional marasmus
0.000 0.492 0.508
E40 Kwashiorkor
0.000 0.492 0.508
L40.1 Generalised pustular psoriasis
0.000 0.494 0.506
Chapter X Diseases of the respiratory system
0.000 0.494 0.506
E04.1 Non-toxic single thyroid nodule
0.000 0.495 0.505
E13 Other specified diabetes mellitus
0.001 0.495 0.505
Chapter VI Diseases of the nervous system
0.000 0.495 0.505
# Top node
0.000 0.496 0.504
J33.9 Nasal polyp, unspecified
0.000 0.496 0.504
J32.9 Chronic sinusitis, unspecified
0.000 0.500 0.500
E46 Unspecified protein-energy malnutrition
0.000 0.501 0.498
E89.0 Postprocedural hypothyroidism
0.000 0.503 0.497
H30 Chorioretinal inflammation
0.000 0.504 0.496
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.509 0.491
J39 Other diseases of upper respiratory tract
0.000 0.514 0.486
Chapter VII Diseases of the eye and adnexa
0.000 0.518 0.482
E11.3 With ophthalmic complications
0.000 0.520 0.480
J38.4 Oedema of larynx
0.000 0.521 0.479
B37.8 Candidiasis of other sites
0.000 0.522 0.478
Chapter I Certain infectious and parasitic diseases
0.000 0.524 0.476
M13 Other arthritis
0.000 0.527 0.472
J20-J22 Other acute lower respiratory infections
0.000 0.528 0.472
H33.4 Traction detachment of retina
0.000 0.529 0.470
J38.1 Polyp of vocal cord and larynx
0.000 0.530 0.470
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.530 0.470
B37 Candidiasis
0.000 0.530 0.470
B35-B49 Mycoses
0.000 0.532 0.468
E50.9 Vitamin A deficiency, unspecified
0.000 0.532 0.468
E50.8 Other manifestations of vitamin A deficiency
0.000 0.532 0.468
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.532 0.468
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.532 0.468
E50.5 Vitamin A deficiency with night blindness
0.000 0.532 0.468
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.532 0.468
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.532 0.468
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.532 0.468
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.532 0.468
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.532 0.468
E56.9 Vitamin deficiency, unspecified
0.000 0.532 0.468
E56.8 Deficiency of other vitamins
0.000 0.532 0.468
E56.1 Deficiency of vitamin K
0.000 0.532 0.468
E56.0 Deficiency of vitamin E
0.000 0.532 0.468
E63.9 Nutritional deficiency, unspecified
0.000 0.532 0.468
E63.8 Other specified nutritional deficiencies
0.000 0.532 0.468
E63.1 Imbalance of constituents of food intake
0.000 0.532 0.468
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.532 0.468
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.532 0.468
E64.8 Sequelae of other nutritional deficiencies
0.000 0.532 0.468
E64.3 Sequelae of rickets
0.000 0.532 0.468
E64.2 Sequelae of vitamin C deficiency
0.000 0.532 0.468
E64.1 Sequelae of vitamin A deficiency
0.000 0.532 0.468
E64.0 Sequelae of protein-energy malnutrition
0.000 0.532 0.468
M11 Other crystal arthropathies
0.000 0.534 0.466
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.535 0.465
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.539 0.461
J32.8 Other chronic sinusitis
0.000 0.540 0.460
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.542 0.458
E79 Disorders of purine and pyrimidine metabolism
0.000 0.544 0.456
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.546 0.454
G40-G47 Episodic and paroxysmal disorders
0.000 0.546 0.454
E77 Disorders of glycoprotein metabolism
0.000 0.547 0.453
E76 Disorders of glycosaminoglycan metabolism
0.000 0.547 0.453
E72 Other disorders of amino-acid metabolism
0.000 0.547 0.453
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.547 0.453
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.547 0.453
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.547 0.453
E51.9 Thiamine deficiency, unspecified
0.000 0.548 0.452
E51.8 Other manifestations of thiamine deficiency
0.000 0.548 0.452
E51.1 Beriberi
0.000 0.548 0.452
E84 Cystic fibrosis
0.000 0.549 0.451
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.550 0.450
G36.9 Acute disseminated demyelination, unspecified
0.000 0.550 0.450
G36.8 Other specified acute disseminated demyelination
0.000 0.550 0.450
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.550 0.450
G36.0 Neuromyelitis optica [Devic]
0.000 0.550 0.450
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.552 0.448
E11.8 With unspecified complications
0.000 0.553 0.447
G45.9 Transient cerebral ischaemic attack, unspecified
0.000 0.554 0.446
M07 Psoriatic and enteropathic arthropathies
0.000 0.555 0.445
G45 Transient cerebral ischaemic attacks and related syndromes
0.000 0.555 0.445
L40.8 Other psoriasis
0.000 0.558 0.441
E61.2 Magnesium deficiency
0.000 0.559 0.441
J38.5 Laryngeal spasm
0.000 0.560 0.440
J38.0 Paralysis of vocal cords and larynx
0.000 0.560 0.440
H34 Retinal vascular occlusions
0.000 0.564 0.436
E07.9 Disorder of thyroid, unspecified
0.000 0.566 0.434
M08.9 Juvenile arthritis, unspecified
0.000 0.566 0.434
M08.8 Other juvenile arthritis
0.000 0.566 0.434
M08.4 Pauciarticular juvenile arthritis
0.000 0.566 0.434
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.566 0.434
M08.2 Juvenile arthritis with systemic onset
0.000 0.566 0.434
M08.1 Juvenile ankylosing spondylitis
0.000 0.566 0.434
M08.0 Juvenile rheumatoid arthritis
0.000 0.566 0.434
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.566 0.434
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.566 0.434
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.566 0.434
M09.0 Juvenile arthritis in psoriasis
0.000 0.566 0.434
J80 Adult respiratory distress syndrome
0.000 0.566 0.434
J32.0 Chronic maxillary sinusitis
0.000 0.567 0.433
J20 Acute bronchitis
0.000 0.567 0.433
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.568 0.432
M05.09 Felty's syndrome (Site unspecified)
0.000 0.569 0.431
M05.08 Felty's syndrome (Other)
0.000 0.569 0.431
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.569 0.431
M05.06 Felty's syndrome (Lower leg)
0.000 0.569 0.431
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.569 0.431
M05.04 Felty's syndrome (Hand)
0.000 0.569 0.431
M05.03 Felty's syndrome (Forearm)
0.000 0.569 0.431
M05.02 Felty's syndrome (Upper arm)
0.000 0.569 0.431
M05.01 Felty's syndrome (Shoulder region)
0.000 0.569 0.431
M05.00 Felty's syndrome (Multiple sites)
0.000 0.569 0.431
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.569 0.431
M05.18 Rheumatoid lung disease (Other)
0.000 0.569 0.431
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.569 0.431
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.569 0.431
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.569 0.431
M05.14 Rheumatoid lung disease (Hand)
0.000 0.569 0.431
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.569 0.431
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.569 0.431
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.569 0.431
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.569 0.431
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.569 0.431
M05.28 Rheumatoid vasculitis (Other)
0.000 0.569 0.431
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.569 0.431
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.569 0.431
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.569 0.431
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.569 0.431
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.569 0.431
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.569 0.431
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.569 0.431
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.569 0.431
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.569 0.431
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.569 0.431
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.569 0.431
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.569 0.431
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.569 0.431
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.569 0.431
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.569 0.431
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.569 0.431
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.569 0.431
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.569 0.431
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.569 0.431
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.569 0.431
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.569 0.431
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.569 0.431
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.569 0.431
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.569 0.431
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.569 0.431
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.569 0.431
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.569 0.431
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.569 0.431
D50-D53 Nutritional anaemias
0.000 0.569 0.431
E51.2 Wernicke's encephalopathy
0.000 0.570 0.430
L40.4 Guttate psoriasis
0.000 0.572 0.428
M10.0 Idiopathic gout
0.000 0.573 0.427
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.574 0.426
E74 Other disorders of carbohydrate metabolism
0.000 0.575 0.425
J32.4 Chronic pansinusitis
0.000 0.577 0.423
J33.1 Polypoid sinus degeneration
0.000 0.581 0.419
E11.1 With ketoacidosis
0.000 0.583 0.417
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.583 0.416
M12.5 Traumatic arthropathy
0.000 0.583 0.416
M12.4 Intermittent hydrarthrosis
0.000 0.583 0.416
M12.3 Palindromic rheumatism
0.000 0.583 0.416
M12.1 Kaschin-Beck disease
0.000 0.583 0.416
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.583 0.416
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.585 0.415
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.585 0.415
M14.4 Arthropathy in amyloidosis
0.000 0.585 0.415
M14.3 Lipoid dermatoarthritis
0.000 0.585 0.415
M14.2 Diabetic arthropathy
0.000 0.585 0.415
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.585 0.415
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.585 0.415
J39.8 Other specified diseases of upper respiratory tract
0.000 0.585 0.415
B37.0 Candidal stomatitis
0.000 0.585 0.415
A63.0 Anogenital (venereal) warts
0.000 0.587 0.413
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.587 0.413
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.590 0.410
E73.8 Other lactose intolerance
0.000 0.591 0.409
E73.1 Secondary lactase deficiency
0.000 0.591 0.409
E73.0 Congenital lactase deficiency
0.000 0.591 0.409
J20.9 Acute bronchitis, unspecified
0.000 0.592 0.408
H46 Optic neuritis
0.000 0.593 0.407
E89.4 Postprocedural ovarian failure
0.000 0.594 0.406
D51 Vitamin B12 deficiency anaemia
0.000 0.597 0.403
E70 Disorders of aromatic amino-acid metabolism
0.000 0.600 0.400
E20-E35 Disorders of other endocrine glands
0.000 0.603 0.397
M13.8 Other specified arthritis
0.000 0.603 0.397
H30.9 Chorioretinal inflammation, unspecified
0.000 0.605 0.394
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.607 0.393
J81 Pulmonary oedema
0.000 0.607 0.393
J39.9 Disease of upper respiratory tract, unspecified
0.000 0.607 0.393
M12.2 Villonodular synovitis (pigmented)
0.000 0.607 0.392
J40-J47 Chronic lower respiratory diseases
0.000 0.610 0.390
M14.6 Neuropathic arthropathy
0.000 0.610 0.389
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.611 0.389
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.612 0.388
L44 Other papulosquamous disorders
0.000 0.613 0.387
L41 Parapsoriasis
0.000 0.613 0.387
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.613 0.387
G47 Sleep disorders
0.000 0.615 0.385
E27 Other disorders of adrenal gland
0.000 0.615 0.385
E83 Disorders of mineral metabolism
0.000 0.615 0.385
D68 Other coagulation defects
0.000 0.616 0.384
L10-L14 Bullous disorders
0.000 0.617 0.383
E88.8 Other specified metabolic disorders
0.000 0.617 0.382
K90.3 Pancreatic steatorrhoea
0.000 0.618 0.382
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.618 0.382
K90.1 Tropical sprue
0.000 0.618 0.382
M10.4 Other secondary gout
0.000 0.618 0.382
M10.3 Gout due to impairment of renal function
0.000 0.618 0.382
M10.2 Drug-induced gout
0.000 0.618 0.382
M10.1 Lead-induced gout
0.000 0.618 0.382
E11.0 With coma
0.000 0.618 0.382
B50-B64 Protozoal diseases
0.000 0.619 0.381
E27.1 Primary adrenocortical insufficiency
0.000 0.620 0.380
G63.2 Diabetic polyneuropathy
0.000 0.620 0.380
J47 Bronchiectasis
0.000 0.622 0.378
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.622 0.378
E89.5 Postprocedural testicular hypofunction
0.000 0.622 0.378
E89.1 Postprocedural hypoinsulinaemia
0.000 0.622 0.378
J39.0 Retropharyngeal and parapharyngeal abscess
0.000 0.623 0.377
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.623 0.377
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.623 0.377
J33.8 Other polyp of sinus
0.000 0.624 0.376
J37 Chronic laryngitis and laryngotracheitis
0.000 0.624 0.375
L20-L30 Dermatitis and eczema
0.000 0.624 0.376
J22 Unspecified acute lower respiratory infection
0.000 0.625 0.375
J38.2 Nodules of vocal cords
0.000 0.626 0.374
A80-A89 Viral infections of the central nervous system
0.000 0.626 0.373
E89.3 Postprocedural hypopituitarism
0.000 0.627 0.373
J38.6 Stenosis of larynx
0.000 0.628 0.372
E11.7 With multiple complications
0.000 0.629 0.371
G62 Other polyneuropathies
0.000 0.629 0.371
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.631 0.369

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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