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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs5006724
log Bayes Factor = 108.151
Chromosome 6   position 31,337,850  (GRCh37) Explore rs5006724 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E14.9 Without complications
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
M45 Ankylosing spondylitis
0.999 0.001 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.998 0.002 0.000
E10.1 With ketoacidosis
0.000 0.002 0.998
E11 Non-insulin-dependent diabetes mellitus
0.000 0.003 0.997
K51.4 Pseudopolyposis of colon
0.995 0.005 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.010 0.990
E20-E35 Disorders of other endocrine glands
0.000 0.011 0.989
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.014 0.986
E00-E07 Disorders of thyroid gland
0.000 0.014 0.986
E05.9 Thyrotoxicosis, unspecified
0.000 0.018 0.982
K51.2 Ulcerative (chronic) proctitis
0.981 0.019 0.000
E10.4 With neurological complications
0.000 0.019 0.981
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.022 0.978
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.025 0.975
K51.3 Ulcerative (chronic) rectosigmoiditis
0.974 0.026 0.000
G35 Multiple sclerosis
0.972 0.028 0.000
E27 Other disorders of adrenal gland
0.000 0.032 0.968
E11.1 With ketoacidosis
0.000 0.047 0.953
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.051 0.949
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.061 0.939
E10.0 With coma
0.000 0.068 0.932
E11.3 With ophthalmic complications
0.000 0.069 0.931
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.075 0.925
E11.0 With coma
0.000 0.085 0.915
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.089 0.911
E10.8 With unspecified complications
0.000 0.093 0.907
E27.1 Primary adrenocortical insufficiency
0.000 0.099 0.901
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.112 0.888
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.124 0.876
E14.1 With ketoacidosis
0.000 0.127 0.873
K51.8 Other ulcerative colitis
0.870 0.130 0.000
E10.6 With other specified complications
0.000 0.132 0.868
E27.9 Disorder of adrenal gland, unspecified
0.000 0.134 0.866
K51.5 Mucosal proctocolitis
0.863 0.137 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.147 0.853
E11.9 Without complications
0.000 0.150 0.850
E14.3 With ophthalmic complications
0.000 0.155 0.845
E22 Hyperfunction of pituitary gland
0.000 0.157 0.843
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.164 0.836
E11.5 With peripheral circulatory complications
0.000 0.165 0.835
M45.X2 Ankylosing spondylitis (Cervical region)
0.825 0.175 0.000
E10.2 With renal complications
0.000 0.175 0.825
E14.6 With other specified complications
0.000 0.175 0.825
E24 Cushing's syndrome
0.000 0.185 0.815
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.808 0.192 0.000
E13 Other specified diabetes mellitus
0.000 0.193 0.807
E10.5 With peripheral circulatory complications
0.000 0.211 0.789
G35-G37 Demyelinating diseases of the central nervous system
0.785 0.215 0.000
E05.8 Other thyrotoxicosis
0.000 0.217 0.783
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.217 0.783
E07 Other disorders of thyroid
0.000 0.218 0.782
E16.1 Other hypoglycaemia
0.000 0.220 0.780
M45.X6 Ankylosing spondylitis (Lumbar region)
0.779 0.221 0.000
E23.2 Diabetes insipidus
0.000 0.224 0.776
E14.2 Withrenal complications
0.000 0.227 0.773
E40-E46 Malnutrition
0.000 0.227 0.773
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.240 0.760
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.251 0.749
G37 Other demyelinating diseases of central nervous system
0.741 0.259 0.000
J45 Asthma
0.000 0.271 0.729
E14.8 With unspecified complications
0.000 0.278 0.722
E28 Ovarian dysfunction
0.000 0.281 0.719
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.716 0.284 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.716 0.284 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.716 0.284 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.716 0.284 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.716 0.284 0.000
M06 Other rheumatoid arthritis
0.011 0.285 0.705
E11.7 With multiple complications
0.000 0.285 0.714
E25 Adrenogenital disorders
0.000 0.286 0.713
E24.0 Pituitary-dependent Cushing's disease
0.000 0.290 0.710
E34 Other endocrine disorders
0.000 0.290 0.710
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.291 0.709
E32 Diseases of thymus
0.000 0.291 0.709
E30 Disorders of puberty, not elsewhere classified
0.000 0.291 0.709
G37.9 Demyelinating disease of central nervous system, unspecified
0.709 0.291 0.000
E05.5 Thyroid crisis or storm
0.000 0.293 0.707
E05.4 Thyrotoxicosis factitia
0.000 0.293 0.707
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.293 0.707
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.293 0.707
E00 Congenital iodine-deficiency syndrome
0.000 0.293 0.707
E10.7 With multiple complications
0.000 0.294 0.706
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.296 0.704
E14.5 With peripheral circulatory complications
0.000 0.302 0.698
E22.0 Acromegaly and pituitary gigantism
0.000 0.304 0.696
K51.0 Ulcerative (chronic) enterocolitis
0.694 0.306 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.306 0.694
E27.0 Other adrenocortical overactivity
0.000 0.306 0.694
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.307 0.693
M06.3 Rheumatoid nodule
0.002 0.310 0.688
E29 Testicular dysfunction
0.000 0.310 0.690
E31 Polyglandular dysfunction
0.000 0.311 0.689
E27.8 Other specified disorders of adrenal gland
0.000 0.314 0.686
E13.9 Without complications
0.000 0.322 0.678
E23.7 Disorder of pituitary gland, unspecified
0.000 0.323 0.677
E20 Hypoparathyroidism
0.000 0.324 0.676
E26 Hyperaldosteronism
0.000 0.336 0.664
E07.8 Other specified disorders of thyroid
0.000 0.340 0.660
E11.4 With neurological complications
0.000 0.346 0.654
K90 Intestinal malabsorption
0.000 0.349 0.651
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.351 0.649
E14.4 With neurological complications
0.000 0.351 0.649
M06.34 Rheumatoid nodule (Hand)
0.001 0.352 0.647
E11.8 With unspecified complications
0.000 0.354 0.646
E11.6 With other specified complications
0.000 0.369 0.631
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.388 0.612
E23.1 Drug-induced hypopituitarism
0.000 0.388 0.612
E46 Unspecified protein-energy malnutrition
0.000 0.390 0.610
K51.1 Ulcerative (chronic) ileocolitis
0.609 0.390 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.394 0.605
E22.8 Other hyperfunction of pituitary gland
0.000 0.395 0.605
J45.0 Predominantly allergic asthma
0.000 0.396 0.604
J45.1 Nonallergic asthma
0.000 0.397 0.602
M06.32 Rheumatoid nodule (Upper arm)
0.001 0.398 0.601
E23.6 Other disorders of pituitary gland
0.000 0.399 0.600
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.400 0.599
E28.2 Polycystic ovarian syndrome
0.000 0.401 0.599
G36 Other acute disseminated demyelination
0.598 0.402 0.000
E11.2 With renal complications
0.000 0.405 0.595
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.416 0.584
E22.1 Hyperprolactinaemia
0.000 0.416 0.584
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.416 0.584
E24.3 Ectopic ACTH syndrome
0.000 0.416 0.584
E24.1 Nelson's syndrome
0.000 0.416 0.584
J45.8 Mixed asthma
0.000 0.421 0.579
E13.8 With unspecified complications
0.000 0.421 0.578
E13.7 With multiple complications
0.000 0.421 0.578
E13.6 With other specified complications
0.000 0.421 0.578
E13.5 With peripheral circulatory complications
0.000 0.421 0.578
E13.4 With neurological complications
0.000 0.421 0.578
E13.2 With renal complications
0.000 0.421 0.578
E13.1 With ketoacidosis
0.000 0.421 0.578
E13.0 With coma
0.000 0.421 0.578
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.424 0.576
G37.8 Other specified demyelinating diseases of central nervous system
0.563 0.437 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.438 0.562
E07.1 Dyshormogenetic goitre
0.000 0.439 0.560
E07.0 Hypersecretion of calcitonin
0.000 0.439 0.560
E13.3 With ophthalmic complications
0.000 0.440 0.560
K90.9 Intestinal malabsorption, unspecified
0.000 0.445 0.555
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.446 0.554
E45 Retarded development following protein-energy malnutrition
0.000 0.446 0.554
E43 Unspecified severe protein-energy malnutrition
0.000 0.446 0.554
E42 Marasmic kwashiorkor
0.000 0.446 0.554
E41 Nutritional marasmus
0.000 0.446 0.554
E40 Kwashiorkor
0.000 0.446 0.554
E27.2 Addisonian crisis
0.000 0.454 0.546
M06.37 Rheumatoid nodule (Ankle and foot)
0.001 0.456 0.543
E24.8 Other Cushing's syndrome
0.000 0.461 0.539
E34.9 Endocrine disorder, unspecified
0.000 0.465 0.535
G37.5 Concentric sclerosis [Balo]
0.531 0.469 0.000
G37.4 Subacute necrotising myelitis
0.531 0.469 0.000
G37.2 Central pontine myelinolysis
0.531 0.469 0.000
G37.1 Central demyelination of corpus callosum
0.531 0.469 0.000
G37.0 Diffuse sclerosis
0.531 0.469 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.476 0.523
M06.8 Other specified rheumatoid arthritis
0.007 0.479 0.514
E07.9 Disorder of thyroid, unspecified
0.000 0.482 0.518
E26.9 Hyperaldosteronism, unspecified
0.000 0.484 0.516
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.484 0.516
E28.9 Ovarian dysfunction, unspecified
0.000 0.484 0.515
E28.8 Other ovarian dysfunction
0.000 0.484 0.515
E28.1 Androgen excess
0.000 0.484 0.515
E28.0 Oestrogen excess
0.000 0.484 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M06.2 Rheumatoid bursitis
0.008 0.487 0.505
M06.1 Adult-onset Still's disease
0.008 0.487 0.505
E25.9 Adrenogenital disorder, unspecified
0.000 0.488 0.512
E25.8 Other adrenogenital disorders
0.000 0.488 0.512
K90.8 Other intestinal malabsorption
0.000 0.489 0.511
E34.0 Carcinoid syndrome
0.000 0.491 0.509
E34.5 Androgen resistance syndrome
0.000 0.491 0.509
E34.4 Constitutional tall stature
0.000 0.491 0.509
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.491 0.509
E34.1 Other hypersecretion of intestinal hormones
0.000 0.491 0.509
E30.9 Disorder of puberty, unspecified
0.000 0.492 0.508
E30.8 Other disorders of puberty
0.000 0.492 0.508
E30.1 Precocious puberty
0.000 0.492 0.508
E30.0 Delayed puberty
0.000 0.492 0.508
E32.9 Disease of thymus, unspecified
0.000 0.492 0.508
E32.8 Other diseases of thymus
0.000 0.492 0.508
E32.1 Abscess of thymus
0.000 0.492 0.508
E32.0 Persistent hyperplasia of thymus
0.000 0.492 0.508
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.492 0.508
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.492 0.508
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.492 0.508
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.493 0.507
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.493 0.507
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.493 0.507
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.493 0.507
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.493 0.507
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.493 0.507
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.493 0.507
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.493 0.507
M06.30 Rheumatoid nodule (Multiple sites)
0.002 0.494 0.505
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.496 0.504
E34.8 Other specified endocrine disorders
0.000 0.502 0.497
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.497 0.503 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.002 0.505 0.493
M06.38 Rheumatoid nodule (Other)
0.002 0.505 0.493
M06.36 Rheumatoid nodule (Lower leg)
0.002 0.505 0.493
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.002 0.505 0.493
M06.33 Rheumatoid nodule (Forearm)
0.002 0.505 0.493
M06.31 Rheumatoid nodule (Shoulder region)
0.002 0.505 0.493
E29.9 Testicular dysfunction, unspecified
0.000 0.505 0.495
E29.8 Other testicular dysfunction
0.000 0.505 0.495
E29.0 Testicular hyperfunction
0.000 0.505 0.495
E31.9 Polyglandular dysfunction, unspecified
0.000 0.506 0.494
E31.8 Other polyglandular dysfunction
0.000 0.506 0.494
E31.1 Polyglandular hyperfunction
0.000 0.506 0.494
E34.3 Short stature, not elsewhere classified
0.000 0.508 0.492
E20.8 Other hypoparathyroidism
0.000 0.515 0.485
E20.1 Pseudohypoparathyroidism
0.000 0.515 0.485
E20.0 Idiopathic hypoparathyroidism
0.000 0.515 0.485
E26.8 Other hyperaldosteronism
0.000 0.524 0.476
E26.1 Secondary hyperaldosteronism
0.000 0.524 0.476
E29.1 Testicular hypofunction
0.000 0.524 0.475
E03 Other hypothyroidism
0.000 0.525 0.475
E31.0 Autoimmune polyglandular failure
0.000 0.526 0.474
K90.3 Pancreatic steatorrhoea
0.000 0.533 0.467
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.533 0.467
K90.1 Tropical sprue
0.000 0.533 0.467
G36.0 Neuromyelitis optica [Devic]
0.463 0.537 0.000
M06.4 Inflammatory polyarthropathy
0.007 0.543 0.450
H20.9 Iridocyclitis, unspecified
0.457 0.543 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.548 0.452
E20.9 Hypoparathyroidism, unspecified
0.000 0.548 0.452
E23.0 Hypopituitarism
0.000 0.548 0.452
E06 Thyroiditis
0.000 0.557 0.443
G36.9 Acute disseminated demyelination, unspecified
0.429 0.571 0.000
G36.8 Other specified acute disseminated demyelination
0.429 0.571 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.429 0.571 0.000
H20 Iridocyclitis
0.408 0.592 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.602 0.397
E44.0 Moderate protein-energy malnutrition
0.000 0.602 0.397
E28.3 Primary ovarian failure
0.000 0.608 0.391
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.611 0.389
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.005 0.618 0.377
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.620 0.380
M06.88 Other specified rheumatoid arthritis (Other)
0.005 0.626 0.368
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.005 0.626 0.368
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.005 0.626 0.368
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.005 0.626 0.368
M06.84 Other specified rheumatoid arthritis (Hand)
0.005 0.626 0.368
M06.83 Other specified rheumatoid arthritis (Forearm)
0.005 0.626 0.368
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.005 0.626 0.368
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.005 0.626 0.368
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.005 0.626 0.368
M06.19 Adult-onset Still's disease (Site unspecified)
0.006 0.632 0.362
M06.18 Adult-onset Still's disease (Other)
0.006 0.632 0.362
M06.17 Adult-onset Still's disease (Ankle and foot)
0.006 0.632 0.362
M06.16 Adult-onset Still's disease (Lower leg)
0.006 0.632 0.362
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.006 0.632 0.362
M06.14 Adult-onset Still's disease (Hand)
0.006 0.632 0.362
M06.13 Adult-onset Still's disease (Forearm)
0.006 0.632 0.362
M06.12 Adult-onset Still's disease (Upper arm)
0.006 0.632 0.362
M06.11 Adult-onset Still's disease (Shoulder region)
0.006 0.632 0.362
M06.10 Adult-onset Still's disease (Multiple sites)
0.006 0.632 0.362
M06.29 Rheumatoid bursitis (Site unspecified)
0.006 0.632 0.362
M06.28 Rheumatoid bursitis (Other)
0.006 0.632 0.362
M06.27 Rheumatoid bursitis (Ankle and foot)
0.006 0.632 0.362
M06.26 Rheumatoid bursitis (Lower leg)
0.006 0.632 0.362
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.006 0.632 0.362
M06.24 Rheumatoid bursitis (Hand)
0.006 0.632 0.362
M06.23 Rheumatoid bursitis (Forearm)
0.006 0.632 0.362
M06.22 Rheumatoid bursitis (Upper arm)
0.006 0.632 0.362
M06.21 Rheumatoid bursitis (Shoulder region)
0.006 0.632 0.362
M06.20 Rheumatoid bursitis (Multiple sites)
0.006 0.632 0.362
E26.0 Primary hyperaldosteronism
0.000 0.632 0.368
E21.4 Other specified disorders of parathyroid gland
0.000 0.639 0.361
H20.0 Acute and subacute iridocyclitis
0.357 0.643 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.650 0.350
H20.1 Chronic iridocyclitis
0.347 0.653 0.000
E03.5 Myxoedema coma
0.000 0.659 0.341
E03.4 Atrophy of thyroid (acquired)
0.000 0.659 0.341
E03.3 Postinfectious hypothyroidism
0.000 0.659 0.341
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.659 0.341
H20.8 Other iridocyclitis
0.339 0.661 0.000
E21.0 Primary hyperparathyroidism
0.000 0.666 0.334
M06.48 Inflammatory polyarthropathy (Other)
0.005 0.672 0.323
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.005 0.672 0.323
M06.46 Inflammatory polyarthropathy (Lower leg)
0.005 0.672 0.323
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.005 0.672 0.323
M06.44 Inflammatory polyarthropathy (Hand)
0.005 0.672 0.323
M06.43 Inflammatory polyarthropathy (Forearm)
0.005 0.672 0.323
M06.42 Inflammatory polyarthropathy (Upper arm)
0.005 0.672 0.323
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.005 0.672 0.323
E03.1 Congenital hypothyroidism without goitre
0.000 0.674 0.325
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.004 0.675 0.321
E03.8 Other specified hypothyroidism
0.000 0.677 0.323
E21.2 Other hyperparathyroidism
0.000 0.679 0.320
E06.4 Drug-induced thyroiditis
0.000 0.682 0.317
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.682 0.317
E06.0 Acute thyroiditis
0.000 0.682 0.317
E06.1 Subacute thyroiditis
0.000 0.683 0.316
E21.3 Hyperparathyroidism, unspecified
0.000 0.687 0.313
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.691 0.309
E06.5 Other chronic thyroiditis
0.000 0.696 0.304
H20.2 Lens-induced iridocyclitis
0.293 0.707 0.000
E50-E64 Other nutritional deficiencies
0.000 0.709 0.291
K50-K52 Noninfective enteritis and colitis
0.282 0.717 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.005 0.724 0.271
E83 Disorders of mineral metabolism
0.265 0.734 0.001
E67 Other hyperalimentation
0.000 0.749 0.251
E68 Sequelae of hyperalimentation
0.000 0.749 0.251
E06.3 Autoimmune thyroiditis
0.000 0.749 0.251
E51 Thiamine deficiency
0.000 0.779 0.221
E06.9 Thyroiditis, unspecified
0.000 0.784 0.216
E58 Dietary calcium deficiency
0.000 0.789 0.211
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.791 0.209
E63 Other nutritional deficiencies
0.000 0.791 0.209
E50 Vitamin A deficiency
0.000 0.791 0.209
E60 Dietary zinc deficiency
0.000 0.791 0.209
E59 Dietary selenium deficiency
0.000 0.791 0.209
E54 Ascorbic acid deficiency
0.000 0.791 0.209
E52 Niacin deficiency [pellagra]
0.000 0.791 0.209
E65 Localised adiposity
0.000 0.805 0.195
E83.9 Disorder of mineral metabolism, unspecified
0.190 0.809 0.001
E83.8 Other disorders of mineral metabolism
0.190 0.809 0.001
E83.2 Disorders of zinc metabolism
0.190 0.809 0.001
E83.0 Disorders of copper metabolism
0.190 0.809 0.001
E56 Other vitamin deficiencies
0.000 0.813 0.186
K50 Crohn's disease [regional enteritis]
0.186 0.814 0.000
E67.8 Other specified hyperalimentation
0.000 0.820 0.180
E67.3 Hypervitaminosis D
0.000 0.820 0.180
E67.2 Megavitamin-B6 syndrome
0.000 0.820 0.180
E67.1 Hypercarotenaemia
0.000 0.820 0.180
E67.0 Hypervitaminosis A
0.000 0.820 0.180
M07.3 Other psoriatic arthropathies
0.180 0.820 0.000
H36.0 Diabetic retinopathy
0.000 0.821 0.179
E83.3 Disorders of phosphorus metabolism
0.178 0.821 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.177 0.823 0.000
E51.2 Wernicke's encephalopathy
0.000 0.829 0.171
M07.39 Other psoriatic arthropathies (Site unspecified)
0.168 0.832 0.000
E83.5 Disorders of calcium metabolism
0.166 0.834 0.000
E83.4 Disorders of magnesium metabolism
0.164 0.836 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.162 0.838 0.000
K50.9 Crohn's disease, unspecified
0.161 0.839 0.000
K52 Other non-infective gastro-enteritis and colitis
0.161 0.839 0.000
E61 Deficiency of other nutrient elements
0.000 0.840 0.159
E51.9 Thiamine deficiency, unspecified
0.000 0.841 0.159
E51.8 Other manifestations of thiamine deficiency
0.000 0.841 0.159
E51.1 Beriberi
0.000 0.841 0.159
M45-M49 Spondylopathies
0.157 0.843 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.155 0.845 0.000
E55 Vitamin D deficiency
0.000 0.847 0.153
H21 Other disorders of iris and ciliary body
0.152 0.848 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.151 0.849 0.000
K52.3 Indeterminate colitis
0.150 0.850 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.850 0.150
E50.8 Other manifestations of vitamin A deficiency
0.000 0.850 0.150
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.850 0.150
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.850 0.150
E50.5 Vitamin A deficiency with night blindness
0.000 0.850 0.150
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.850 0.150
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.850 0.150
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.850 0.150
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.850 0.150
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.850 0.150
E63.9 Nutritional deficiency, unspecified
0.000 0.850 0.150
E63.8 Other specified nutritional deficiencies
0.000 0.850 0.150
E63.1 Imbalance of constituents of food intake
0.000 0.850 0.150
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.850 0.150
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.850 0.150
E64.8 Sequelae of other nutritional deficiencies
0.000 0.850 0.150
E64.3 Sequelae of rickets
0.000 0.850 0.150
E64.2 Sequelae of vitamin C deficiency
0.000 0.850 0.150
E64.1 Sequelae of vitamin A deficiency
0.000 0.850 0.150
E64.0 Sequelae of protein-energy malnutrition
0.000 0.850 0.150
K50.1 Crohn's disease of large intestine
0.149 0.851 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.148 0.852 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.146 0.854 0.000
M07 Psoriatic and enteropathic arthropathies
0.128 0.859 0.014
M07.36 Other psoriatic arthropathies (Lower leg)
0.140 0.860 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.139 0.861 0.000
M07.38 Other psoriatic arthropathies (Other)
0.138 0.861 0.000
M06.0 Seronegative rheumatoid arthritis
0.010 0.863 0.127
E56.9 Vitamin deficiency, unspecified
0.000 0.866 0.134
E56.8 Deficiency of other vitamins
0.000 0.866 0.134
E56.0 Deficiency of vitamin E
0.000 0.866 0.134
K52.1 Toxic gastro-enteritis and colitis
0.132 0.868 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.129 0.871 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.129 0.871 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.125 0.875 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.124 0.876 0.000
M05-M14 Inflammatory polyarthropathies
0.089 0.877 0.034
H21.8 Other specified disorders of iris and ciliary body
0.122 0.878 0.000
E04 Other non-toxic goitre
0.000 0.885 0.115
E61.9 Deficiency of nutrient element, unspecified
0.000 0.885 0.114
E61.8 Deficiency of other specified nutrient elements
0.000 0.885 0.114
E61.7 Deficiency of multiple nutrient elements
0.000 0.885 0.114
E61.6 Vanadium deficiency
0.000 0.885 0.114
E61.5 Molybdenum deficiency
0.000 0.885 0.114
E61.4 Chromium deficiency
0.000 0.885 0.114
E61.3 Manganese deficiency
0.000 0.885 0.114
E61.0 Copper deficiency
0.000 0.885 0.114
M48 Other spondylopathies
0.112 0.887 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.888 0.112
E56.1 Deficiency of vitamin K
0.001 0.888 0.111
H21.2 Degeneration of iris and ciliary body
0.111 0.889 0.000
E55.0 Rickets, active
0.000 0.890 0.110
E53 Deficiency of other B group vitamins
0.000 0.890 0.110
H21.4 Pupillary membranes
0.109 0.891 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.109 0.891 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.107 0.893 0.000
I10 Essential (primary) hypertension
0.000 0.894 0.106
H16 Keratitis
0.105 0.895 0.000
H17 Corneal scars and opacities
0.104 0.896 0.000
E61.1 Iron deficiency
0.000 0.897 0.103
M07.6 Other enteropathic arthropathies
0.093 0.898 0.010
M48.5 Collapsed vertebra, not elsewhere classified
0.102 0.898 0.000
M07.5 Arthropathy in ulcerative colitis
0.092 0.898 0.010
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.092 0.898 0.010
M07.2 Psoriatic spondylitis
0.092 0.898 0.010
M07.1 Arthritis mutilans
0.092 0.898 0.010
M07.0 Distal interphalangeal psoriatic arthropathy
0.092 0.898 0.010
K50.0 Crohn's disease of small intestine
0.099 0.901 0.000
H21.9 Disorder of iris and ciliary body, unspecified
0.098 0.902 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.007 0.902 0.091
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.007 0.902 0.091
M06.04 Seronegative rheumatoid arthritis (Hand)
0.007 0.902 0.091
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.007 0.902 0.091
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.007 0.902 0.091
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.098 0.902 0.000
K75.4 Autoimmune hepatitis
0.000 0.902 0.098
I83.0 Varicose veins of lower extremities with ulcer
0.098 0.902 0.000
H22.1 Iridocyclitis in other diseases classified elsewhere
0.097 0.902 0.000
I83 Varicose veins of lower extremities
0.098 0.902 0.000
M49 Spondylopathies in diseases classified elsewhere
0.096 0.904 0.000
M00-M03 Infectious arthropathies
0.094 0.906 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.093 0.907 0.000
M00 Pyogenic arthritis
0.093 0.907 0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
0.093 0.907 0.000
K75 Other inflammatory liver diseases
0.000 0.907 0.093
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.092 0.908 0.000
H15 Disorders of sclera
0.091 0.909 0.000
M00.9 Pyogenic arthritis, unspecified
0.091 0.909 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.090 0.910 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.008 0.910 0.083
M02 Reactive arthropathies
0.090 0.910 0.000
K70-K77 Diseases of liver
0.000 0.910 0.090
M08 Juvenile arthritis
0.066 0.910 0.024
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere
0.089 0.911 0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere
0.089 0.911 0.000
K74 Fibrosis and cirrhosis of liver
0.000 0.911 0.089
H21.0 Hyphaema
0.089 0.911 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.064 0.911 0.025
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.088 0.912 0.000
M12 Other specific arthropathies
0.065 0.912 0.022
M05 Seropositive rheumatoid arthritis
0.058 0.913 0.029
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.087 0.913 0.000
M48.9 Spondylopathy, unspecified
0.085 0.915 0.000
K72 Hepatic failure, not elsewhere classified
0.000 0.915 0.085
E61.2 Magnesium deficiency
0.001 0.916 0.083
M11 Other crystal arthropathies
0.066 0.916 0.017
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.008 0.917 0.075
H16.0 Corneal ulcer
0.083 0.917 0.000
E04.8 Other specified non-toxic goitre
0.000 0.917 0.082
H16.9 Keratitis, unspecified
0.083 0.917 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.082 0.917 0.000
K74.6 Other and unspecified cirrhosis of liver
0.000 0.918 0.082
M02.3 Reiter's disease
0.082 0.918 0.000
K73 Chronic hepatitis, not elsewhere classified
0.000 0.918 0.082
K72.9 Hepatic failure, unspecified
0.000 0.919 0.081
M48.4 Fatigue fracture of vertebra
0.081 0.919 0.000
M48.3 Traumatic spondylopathy
0.081 0.919 0.000
M48.2 Kissing spine
0.081 0.919 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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