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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0122
log Bayes Factor = 219.114
contains 9 variants:
rs7521578
lBF = 17.143
Chr 1 : 158,736,201
rs77620456
lBF = 16.281
Chr 1 : 214,788,839
rs76361614
lBF = 22.055
Chr 2 : 37,527,216
rs72833065
lBF = 17.779
Chr 6 : 24,419,556
rs17423218
lBF = 17.683
Chr 8 : 67,758,401
rs45559032
lBF = 16.801
Chr10 : 12,541,457
rs187353341
lBF = 19.043
Chr12 : 121,557,376
rs55722931
lBF = 16.578
Chr14 : 23,586,795
rs76475900
lBF = 15.263
Chr16 : 59,672,738
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M25.5 Pain in joint
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
M25 Other joint disorders, not elsewhere classified
1.000 0.000 0.000
G40-G47 Episodic and paroxysmal disorders
1.000 0.000 0.000
G90-G99 Other disorders of the nervous system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
K08 Other disorders of teeth and supporting structures
1.000 0.000 0.000
K80 Cholelithiasis
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
1.000 0.000 0.000
G47 Sleep disorders
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
1.000 0.000 0.000
Z00-Z13 Persons encountering health services for examination and investigation
1.000 0.000 0.000
I05-I09 Chronic rheumatic heart diseases
1.000 0.000 0.000
G93 Other disorders of brain
1.000 0.000 0.000
S00 Superficial injury of head
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
1.000 0.000 0.000
M79 Other soft tissue disorders, not elsewhere classified
1.000 0.000 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
1.000 0.000 0.000
I08 Multiple valve diseases
1.000 0.000 0.000
M25.56 Pain in joint (Lower leg)
1.000 0.000 0.000
S60-S69 Injuries to the wrist and hand
1.000 0.000 0.000
N18 Chronic renal failure
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
K76 Other diseases of liver
1.000 0.000 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
1.000 0.000 0.000
M80-M85 Disorders of bone density and structure
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
M47 Spondylosis
0.999 0.001 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.999 0.001 0.000
S20-S29 Injuries to the thorax
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.999 0.001 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.999 0.001 0.000
I51 Complications and ill-defined descriptions of heart disease
0.999 0.001 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.999 0.001 0.000
M47.8 Other spondylosis
0.999 0.001 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.999 0.001 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.999 0.001 0.000
I63 Cerebral infarction
0.998 0.002 0.000
H65-H75 Diseases of middle ear and mastoid
0.998 0.002 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.998 0.002 0.000
G81 Hemiplegia
0.998 0.002 0.000
I69 Sequelae of cerebrovascular disease
0.998 0.002 0.000
I10-I15 Hypertensive diseases
0.998 0.002 0.000
O26.8 Other specified pregnancy-related conditions
0.998 0.002 0.000
G47.3 Sleep apnoea
0.998 0.002 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.998 0.002 0.000
M23 Internal derangement of knee
0.998 0.002 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.998 0.002 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
Q60-Q64 Congenital malformations of the urinary system
0.998 0.002 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.998 0.002 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.998 0.002 0.000
G81.9 Hemiplegia, unspecified
0.998 0.002 0.000
M54 Dorsalgia
0.997 0.003 0.000
I45 Other conduction disorders
0.997 0.003 0.000
E70-E90 Metabolic disorders
0.997 0.003 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.997 0.003 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.997 0.003 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
E11.9 Without complications
0.996 0.004 0.000
S40-S49 Injuries to the shoulder and upper arm
0.996 0.004 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.996 0.004 0.000
M25.4 Effusion of joint
0.996 0.004 0.000
D68 Other coagulation defects
0.996 0.004 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.996 0.004 0.000
O80-O84 Delivery
0.996 0.004 0.000
S00.9 Superficial injury of head, part unspecified
0.995 0.005 0.000
K83 Other diseases of biliary tract
0.995 0.005 0.000
I77 Other disorders of arteries and arterioles
0.995 0.005 0.000
O20 Haemorrhage in early pregnancy
0.995 0.005 0.000
I49 Other cardiac arrhythmias
0.995 0.005 0.000
M84 Disorders of continuity of bone
0.995 0.005 0.000
Z35 Supervision of high-risk pregnancy
0.995 0.005 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.995 0.005 0.000
I44 Atrioventricular and left bundle-branch block
0.994 0.006 0.000
R00 Abnormalities of heart beat
0.994 0.006 0.000
H90-H95 Other disorders of ear
0.994 0.006 0.000
I10 Essential (primary) hypertension
0.994 0.006 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.994 0.006 0.000
M23.8 Other internal derangements of knee
0.994 0.006 0.000
N17 Acute renal failure
0.994 0.006 0.000
I20 Angina pectoris
0.994 0.006 0.000
R00.1 Bradycardia, unspecified
0.994 0.006 0.000
K08.3 Retained dental root
0.993 0.007 0.000
M47.82 Other spondylosis (Cervical region)
0.993 0.007 0.000
I20.8 Other forms of angina pectoris
0.993 0.007 0.000
H90 Conductive and sensorineural hearing loss
0.993 0.007 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.992 0.008 0.000
I42 Cardiomyopathy
0.992 0.008 0.000
E65-E68 Obesity and other hyperalimentation
0.992 0.008 0.000
G95 Other diseases of spinal cord
0.992 0.008 0.000
I51.8 Other ill-defined heart diseases
0.992 0.008 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.992 0.008 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.992 0.008 0.000
T90 Sequelae of injuries of head
0.992 0.008 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.991 0.009 0.000
M25.46 Effusion of joint (Lower leg)
0.991 0.009 0.000
N18.5 Chronic kidney disease, stage 5
0.991 0.009 0.000
E20-E35 Disorders of other endocrine glands
0.990 0.010 0.000
J09-J18 Influenza and pneumonia
0.990 0.010 0.000
F41 Other anxiety disorders
0.990 0.010 0.000
G44 Other headache syndromes
0.990 0.010 0.000
W20-W49 Exposure to inanimate mechanical forces
0.990 0.010 0.000
S80-S89 Injuries to the knee and lower leg
0.990 0.010 0.000
R73 Elevated blood glucose level
0.989 0.011 0.000
Y40 Systemic antibiotics
0.989 0.011 0.000
Z04 Examination and observation for other reasons
0.989 0.011 0.000
Q61 Cystic kidney disease
0.988 0.012 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.988 0.012 0.000
I45.1 Other and unspecified right bundle-branch block
0.988 0.012 0.000
M65-M68 Disorders of synovium and tendon
0.988 0.012 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.988 0.012 0.000
N17.9 Acute renal failure, unspecified
0.987 0.013 0.000
Chapter XXII Codes for special purposes
0.987 0.013 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.987 0.013 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.987 0.013 0.000
H90.2 Conductive hearing loss, unspecified
0.987 0.013 0.000
M21 Other acquired deformities of limbs
0.987 0.013 0.000
Z36 Antenatal screening
0.987 0.013 0.000
E66 Obesity
0.987 0.013 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.986 0.014 0.000
Z04.8 Examination and observation for other specified reasons
0.986 0.014 0.000
M20 Acquired deformities of fingers and toes
0.986 0.014 0.000
I63.8 Other cerebral infarction
0.985 0.015 0.000
S01 Open wound of head
0.985 0.015 0.000
Y95 Nosocomial condition
0.985 0.015 0.000
Y84.6 Urinary catheterisation
0.985 0.015 0.000
N18.0 End-stage renal disease
0.985 0.015 0.000
K07 Dentofacial anomalies [including malocclusion]
0.985 0.015 0.000
I31 Other diseases of pericardium
0.985 0.015 0.000
S42 Fracture of shoulder and upper arm
0.984 0.016 0.000
S02 Fracture of skull and facial bones
0.984 0.016 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.984 0.016 0.000
S27 Injury of other and unspecified intrathoracic organs
0.983 0.017 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.983 0.017 0.000
H53-H54 Visual disturbances and blindness
0.983 0.017 0.000
N40-N51 Diseases of male genital organs
0.983 0.017 0.000
G93.3 Postviral fatigue syndrome
0.982 0.018 0.000
K80.4 Calculus of bile duct with cholecystitis
0.982 0.018 0.000
G43 Migraine
0.982 0.018 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.982 0.018 0.000
K75 Other inflammatory liver diseases
0.981 0.019 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.980 0.020 0.000
G95.2 Cord compression, unspecified
0.980 0.020 0.000
T86 Failure and rejection of transplanted organs and tissues
0.979 0.021 0.000
I51.7 Cardiomegaly
0.979 0.021 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.978 0.022 0.000
H54 Blindness and low vision
0.978 0.022 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.978 0.022 0.000
E11.2 With renal complications
0.977 0.023 0.000
T93 Sequelae of injuries of lower limb
0.976 0.024 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.976 0.024 0.000
M79.8 Other specified soft tissue disorders
0.976 0.024 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.975 0.025 0.000
R06 Abnormalities of breathing
0.975 0.025 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.974 0.026 0.000
O20.0 Threatened abortion
0.973 0.027 0.000
S06 Intracranial injury
0.973 0.027 0.000
O60-O75 Complications of labour and delivery
0.973 0.027 0.000
R01 Cardiac murmurs and other cardiac sounds
0.972 0.028 0.000
K12 Stomatitis and related lesions
0.972 0.028 0.000
M91-M94 Chondropathies
0.972 0.028 0.000
M65 Synovitis and tenosynovitis
0.972 0.028 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.971 0.029 0.000
C64-C68 Malignant neoplasms of urinary tract
0.971 0.029 0.000
E78.5 Hyperlipidaemia, unspecified
0.971 0.029 0.000
I08.0 Disorders of both mitral and aortic valves
0.970 0.030 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.970 0.030 0.000
A30-A49 Other bacterial diseases
0.969 0.031 0.000
K05 Gingivitis and periodontal diseases
0.969 0.031 0.000
I82 Other venous embolism and thrombosis
0.968 0.032 0.000
Z75 Problems related to medical facilities and other health care
0.968 0.032 0.000
D68.9 Coagulation defect, unspecified
0.968 0.032 0.000
Z30 Contraceptive management
0.967 0.033 0.000
D69 Purpura and other haemorrhagic conditions
0.967 0.033 0.000
J90-J94 Other diseases of pleura
0.967 0.033 0.000
M20.3 Other deformity of hallux (acquired)
0.966 0.034 0.000
Y84.8 Other medical procedures
0.965 0.035 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.965 0.035 0.000
S64 Injury of nerves at wrist and hand level
0.965 0.035 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.964 0.036 0.000
M25.9 Joint disorder, unspecified
0.964 0.036 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.964 0.036 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.964 0.036 0.000
W00-W19 Falls
0.964 0.036 0.000
T92 Sequelae of injuries of upper limb
0.963 0.037 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.963 0.037 0.000
G50 Disorders of trigeminal nerve
0.963 0.037 0.000
O82 Single delivery by Caesarean section
0.963 0.037 0.000
Y40.0 Penicillins
0.962 0.038 0.000
D00-D09 In situ neoplasms
0.962 0.038 0.000
H54.0 Blindness, both eyes
0.961 0.039 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.961 0.039 0.000
E66.9 Obesity, unspecified
0.961 0.039 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.961 0.039 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.961 0.039 0.000
R74 Abnormal serum enzyme levels
0.961 0.039 0.000
M05-M14 Inflammatory polyarthropathies
0.960 0.040 0.000
R73.0 Abnormal glucose tolerance test
0.960 0.040 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.960 0.040 0.000
M20.5 Other deformities of toe(s) (acquired)
0.959 0.041 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.959 0.041 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.958 0.042 0.000
G40 Epilepsy
0.958 0.042 0.000
M48 Other spondylopathies
0.957 0.043 0.000
H10-H13 Disorders of conjunctiva
0.956 0.044 0.000
K75.8 Other specified inflammatory liver diseases
0.956 0.044 0.000
J92 Pleural plaque
0.955 0.045 0.000
S27.0 Traumatic pneumothorax
0.955 0.045 0.000
M79.6 Pain in limb
0.955 0.045 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.954 0.046 0.000
G44.2 Tension-type headache
0.954 0.046 0.000
Q63 Other congenital malformations of kidney
0.954 0.046 0.000
N00-N08 Glomerular diseases
0.953 0.047 0.000
I44.6 Other and unspecified fascicular block
0.953 0.047 0.000
M25.52 Pain in joint (Upper arm)
0.953 0.047 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.953 0.047 0.000
E40-E46 Malnutrition
0.952 0.048 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.952 0.048 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.951 0.049 0.000
E11.4 With neurological complications
0.951 0.049 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.951 0.049 0.000
G93.0 Cerebral cysts
0.950 0.050 0.000
S50-S59 Injuries to the elbow and forearm
0.950 0.050 0.000
I31.9 Disease of pericardium, unspecified
0.950 0.050 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.950 0.050 0.000
I86 Varicose veins of other sites
0.950 0.050 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.950 0.050 0.000
S80 Superficial injury of lower leg
0.949 0.051 0.000
E11.5 With peripheral circulatory complications
0.949 0.051 0.000
K10 Other diseases of jaws
0.948 0.052 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.948 0.052 0.000
I49.8 Other specified cardiac arrhythmias
0.947 0.053 0.000
M54.2 Cervicalgia
0.947 0.053 0.000
K11 Diseases of salivary glands
0.947 0.053 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.946 0.054 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.946 0.054 0.000
K83.8 Other specified diseases of biliary tract
0.946 0.054 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.946 0.054 0.000
I47 Paroxysmal tachycardia
0.946 0.054 0.000
O80 Single spontaneous delivery
0.946 0.054 0.000
E87.6 Hypokalaemia
0.945 0.055 0.000
E50-E64 Other nutritional deficiencies
0.945 0.055 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.945 0.055 0.000
K70 Alcoholic liver disease
0.944 0.056 0.000
T79-T79 Certain early complications of trauma
0.944 0.056 0.000
N76 Other inflammation of vagina and vulva
0.944 0.056 0.000
I25.3 Aneurysm of heart
0.944 0.056 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.943 0.057 0.000
G56 Mononeuropathies of upper limb
0.943 0.057 0.000
F30-F39 Mood [affective] disorders
0.943 0.057 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.943 0.057 0.000
M23.3 Other meniscus derangements
0.943 0.057 0.000
S01.9 Open wound of head, part unspecified
0.943 0.057 0.000
E66.8 Other obesity
0.942 0.058 0.000
H65 Nonsuppurative otitis media
0.942 0.058 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.942 0.058 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.941 0.059 0.000
Q61.3 Polycystic kidney, unspecified
0.941 0.059 0.000
N42 Other disorders of prostate
0.941 0.059 0.000
G43.9 Migraine, unspecified
0.941 0.059 0.000
S09 Other and unspecified injuries of head
0.940 0.060 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.940 0.060 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.940 0.060 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.940 0.060 0.000
S22.3 Fracture of rib
0.939 0.061 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.939 0.061 0.000
S00.1 Contusion of eyelid and periocular area
0.938 0.062 0.000
J92.9 Pleural plaque without asbestos
0.938 0.062 0.000
C71 Malignant neoplasm of brain
0.938 0.062 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.938 0.062 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.938 0.062 0.000
N99-N99 Other disorders of the genitourinary system
0.936 0.064 0.000
S42.1 Fracture of scapula
0.936 0.064 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.935 0.065 0.000
M54.4 Lumbago with sciatica
0.935 0.065 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.935 0.065 0.000
K07.6 Temporomandibular joint disorders
0.935 0.065 0.000
T90.9 Sequelae of unspecified injury of head
0.935 0.065 0.000
S02.0 Fracture of vault of skull
0.935 0.065 0.000
M86-M90 Other osteopathies
0.935 0.065 0.000
R01.1 Cardiac murmur, unspecified
0.934 0.066 0.000
I45.9 Conduction disorder, unspecified
0.934 0.066 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.934 0.066 0.000
M21.0 Valgus deformity, not elsewhere classified
0.933 0.067 0.000
R74.8 Abnormal levels of other serum enzymes
0.933 0.067 0.000
G56.2 Lesion of ulnar nerve
0.932 0.068 0.000
O36 Maternal care for other known or suspected foetal problems
0.932 0.068 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.931 0.069 0.000
M79.1 Myalgia
0.931 0.069 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.931 0.069 0.000
K05.6 Periodontal disease, unspecified
0.931 0.069 0.000
S67 Crushing injury of wrist and hand
0.930 0.070 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.930 0.070 0.000
M06 Other rheumatoid arthritis
0.930 0.070 0.000
M94 Other disorders of cartilage
0.930 0.070 0.000
F41.9 Anxiety disorder, unspecified
0.930 0.070 0.000
O21 Excessive vomiting in pregnancy
0.930 0.070 0.000
U89 Agent resistant to other and unspecified antibiotics
0.930 0.070 0.000
C67 Malignant neoplasm of bladder
0.929 0.071 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.929 0.071 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.928 0.072 0.000
M79.67 Pain in limb (Ankle and foot)
0.928 0.072 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.928 0.072 0.000
M54.3 Sciatica
0.928 0.072 0.000
M45 Ankylosing spondylitis
0.927 0.073 0.000
Y52 Agents primarily affecting the cardiovascular system
0.926 0.074 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.926 0.074 0.000
N45 Orchitis and epididymitis
0.925 0.075 0.000
I49.4 Other and unspecified premature depolarisation
0.925 0.075 0.000
S20 Superficial injury of thorax
0.925 0.075 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.925 0.075 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.925 0.075 0.000
M25.50 Pain in joint (Multiple sites)
0.925 0.075 0.000
Z03.3 Observation for suspected nervous system disorder
0.925 0.075 0.000
K83.0 Cholangitis
0.925 0.075 0.000
H18 Other disorders of cornea
0.924 0.076 0.000
I82.8 Embolism and thrombosis of other specified veins
0.924 0.076 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.924 0.076 0.000
O82.0 Delivery by elective Caesarean section
0.924 0.076 0.000
S70-S79 Injuries to the hip and thigh
0.924 0.076 0.000
M25.53 Pain in joint (Forearm)
0.924 0.076 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.923 0.077 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.923 0.077 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.923 0.077 0.000
I77.6 Arteritis, unspecified
0.922 0.078 0.000
W25 Contact with sharp glass
0.922 0.078 0.000
Q63.0 Accessory kidney
0.922 0.078 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.922 0.078 0.000
O24 Diabetes mellitus in pregnancy
0.922 0.078 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.922 0.078 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.921 0.079 0.000
S22.30 Fracture of rib (closed)
0.921 0.079 0.000
Z13 Special screening examination for other diseases and disorders
0.921 0.079 0.000
Z99.2 Dependence on renal dialysis
0.921 0.079 0.000
G50.0 Trigeminal neuralgia
0.920 0.080 0.000
H55-H59 Other disorders of eye and adnexa
0.919 0.081 0.000
H11 Other disorders of conjunctiva
0.919 0.081 0.000
Y84.0 Cardiac catheterisation
0.919 0.081 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.919 0.081 0.000
R73.9 Hyperglycaemia, unspecified
0.918 0.082 0.000
E46 Unspecified protein-energy malnutrition
0.918 0.082 0.000
I44.1 Atrioventricular block, second degree
0.918 0.082 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.917 0.083 0.000
R06.2 Wheezing
0.917 0.083 0.000
R02 Gangrene, not elsewhere classified
0.917 0.083 0.000
M31 Other necrotising vasculopathies
0.916 0.084 0.000
H90.3 Sensorineural hearing loss, bilateral
0.915 0.085 0.000
G47.9 Sleep disorder, unspecified
0.915 0.085 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.915 0.085 0.000
H65.3 Chronic mucoid otitis media
0.914 0.086 0.000
I87 Other disorders of veins
0.914 0.086 0.000
B15-B19 Viral hepatitis
0.914 0.086 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.914 0.086 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.914 0.086 0.000
W44 Foreign body entering into or through eye or natural orifice
0.913 0.087 0.000
M25.7 Osteophyte
0.913 0.087 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.912 0.088 0.000
J00-J06 Acute upper respiratory infections
0.912 0.088 0.000
K86 Other diseases of pancreas
0.911 0.089 0.000
S02.1 Fracture of base of skull
0.911 0.089 0.000
M54.22 Cervicalgia (Cervical region)
0.911 0.089 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.911 0.089 0.000
H74 Other disorders of middle ear and mastoid
0.910 0.090 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.910 0.090 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.910 0.090 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.910 0.090 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.910 0.090 0.000
D68.8 Other specified coagulation defects
0.910 0.090 0.000
T66-T78 Other and unspecified effects of external causes
0.909 0.091 0.000
H66 Suppurative and unspecified otitis media
0.909 0.091 0.000
J20-J22 Other acute lower respiratory infections
0.909 0.091 0.000
I77.8 Other specified disorders of arteries and arterioles
0.909 0.091 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.909 0.091 0.000
M84.0 Malunion of fracture
0.909 0.091 0.000
R27 Other lack of coordination
0.909 0.091 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.909 0.091 0.000
M79.69 Pain in limb (Site unspecified)
0.908 0.092 0.000
S01.3 Open wound of ear
0.908 0.092 0.000
M85 Other disorders of bone density and structure
0.908 0.092 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.908 0.092 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.907 0.093 0.000
U89.8 Agent resistant to other single specified antibiotic
0.907 0.093 0.000
R06.1 Stridor
0.907 0.093 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.907 0.093 0.000
K14 Diseases of tongue
0.907 0.093 0.000
D04 Carcinoma in situ of skin
0.906 0.094 0.000
I20.1 Angina pectoris with documented spasm
0.906 0.094 0.000
H54.4 Blindness, one eye
0.906 0.094 0.000
M48.0 Spinal stenosis
0.906 0.094 0.000
Z94 Transplanted organ and tissue status
0.906 0.094 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.905 0.095 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.905 0.095 0.000
M79.5 Residual foreign body in soft tissue
0.905 0.095 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.905 0.095 0.000
M54.39 Sciatica (Site unspecified)
0.904 0.096 0.000
Z88.6 Personal history of allergy to analgesic agent
0.904 0.096 0.000
M22 Disorders of patella
0.904 0.096 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.904 0.096 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.903 0.097 0.000
E22 Hyperfunction of pituitary gland
0.903 0.097 0.000
Q00-Q07 Congenital malformations of the nervous system
0.903 0.097 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.903 0.097 0.000
K10.8 Other specified diseases of jaws
0.902 0.098 0.000
I49.9 Cardiac arrhythmia, unspecified
0.902 0.098 0.000
I42.0 Dilated cardiomyopathy
0.901 0.099 0.000
Q61.0 Congenital single renal cyst
0.901 0.099 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.901 0.099 0.000
S42.10 Fracture of scapula (closed)
0.901 0.099 0.000
M94.8 Other specified disorders of cartilage
0.900 0.100 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.900 0.100 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.900 0.100 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.899 0.100 0.000
S02.00 Fracture of vault of skull (closed)
0.899 0.101 0.000
F05.9 Delirium, unspecified
0.899 0.101 0.000
R25 Abnormal involuntary movements
0.899 0.101 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.899 0.101 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.899 0.101 0.000
S01.5 Open wound of lip and oral cavity
0.898 0.102 0.000
R06.5 Mouth breathing
0.898 0.102 0.000
G70-G73 Diseases of myoneural junction and muscle
0.898 0.102 0.000
M47.89 Other spondylosis (Site unspecified)
0.898 0.102 0.000
Q23 Congenital malformations of aortic and mitral valves
0.897 0.103 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.897 0.103 0.000
D03 Melanoma in situ
0.896 0.104 0.000
M65.3 Trigger finger
0.896 0.104 0.000
I31.3 Pericardial effusion (noninflammatory)
0.896 0.104 0.000
Z63 Other problems related to primary support group, including family circumstances
0.895 0.105 0.000
R09.0 Asphyxia
0.895 0.105 0.000
F01 Vascular dementia
0.895 0.105 0.000
I85 Oesophageal varices
0.895 0.105 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.894 0.106 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.894 0.106 0.000
G43.1 Migraine with aura [classical migraine]
0.894 0.106 0.000
D10-D36 Benign neoplasms
0.894 0.106 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.894 0.106 0.000
M79.7 Fibromyalgia
0.893 0.107 0.000
C71.1 Frontal lobe
0.893 0.107 0.000
R82 Other abnormal findings in urine
0.893 0.107 0.000
S06.0 Concussion
0.893 0.107 0.000
M24 Other specific joint derangements
0.893 0.107 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.892 0.108 0.000
M21.3 Wrist or foot drop (acquired)
0.891 0.109 0.000
I42.9 Cardiomyopathy, unspecified
0.891 0.109 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.890 0.110 0.000
Z94.0 Kidney transplant status
0.890 0.110 0.000
O47 False labour
0.889 0.111 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.889 0.111 0.000
I46 Cardiac arrest
0.889 0.111 0.000
J20 Acute bronchitis
0.889 0.111 0.000
T82.1 Mechanical complication of cardiac electronic device
0.888 0.112 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.888 0.112 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.888 0.112 0.000
I86.4 Gastric varices
0.888 0.112 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.887 0.113 0.000
O41 Other disorders of amniotic fluid and membranes
0.887 0.113 0.000
M20.0 Deformity of finger(s)
0.887 0.113 0.000
G20-G26 Extrapyramidal and movement disorders
0.887 0.113 0.000
T86.1 Kidney transplant failure and rejection
0.887 0.113 0.000
K07.3 Anomalies of tooth position
0.886 0.114 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.886 0.114 0.000
S00.0 Superficial injury of scalp
0.885 0.115 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.885 0.115 0.000
S81 Open wound of lower leg
0.884 0.116 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.884 0.116 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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