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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72833065
log Bayes Factor = 17.7786
Chromosome 6   position 24,419,556  (GRCh37) Explore rs72833065 on Ensembl!
Variant rs72833065 is part of Cluster X0122

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
G40-G47 Episodic and paroxysmal disorders
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
G47 Sleep disorders
0.998 0.002 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.996 0.004 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.995 0.005 0.000
K80 Cholelithiasis
0.994 0.006 0.000
G47.3 Sleep apnoea
0.994 0.006 0.000
I10-I15 Hypertensive diseases
0.989 0.011 0.000
M45-M49 Spondylopathies
0.985 0.015 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.985 0.015 0.000
G90-G99 Other disorders of the nervous system
0.983 0.017 0.000
I10 Essential (primary) hypertension
0.981 0.019 0.000
Z50 Care involving use of rehabilitation procedures
0.973 0.027 0.000
I60-I69 Cerebrovascular diseases
0.971 0.029 0.000
M20-M25 Other joint disorders
0.968 0.032 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.962 0.038 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.962 0.038 0.000
K50-K52 Noninfective enteritis and colitis
0.960 0.040 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.959 0.041 0.000
M05-M14 Inflammatory polyarthropathies
0.955 0.045 0.000
M80-M85 Disorders of bone density and structure
0.949 0.051 0.000
E65-E68 Obesity and other hyperalimentation
0.949 0.051 0.000
G93 Other disorders of brain
0.949 0.051 0.000
M47 Spondylosis
0.944 0.056 0.000
Z50.1 Other physical therapy
0.944 0.056 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.938 0.062 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.934 0.066 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.933 0.067 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.932 0.068 0.000
M25 Other joint disorders, not elsewhere classified
0.931 0.069 0.000
E50-E64 Other nutritional deficiencies
0.926 0.074 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.925 0.075 0.000
Chapter XX External causes of morbidity and mortality
0.920 0.080 0.000
I63 Cerebral infarction
0.920 0.080 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.919 0.081 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.917 0.083 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.916 0.084 0.000
E66 Obesity
0.914 0.086 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.914 0.086 0.000
Z43 Attention to artificial openings
0.913 0.087 0.000
E00-E07 Disorders of thyroid gland
0.910 0.090 0.000
I30-I52 Other forms of heart disease
0.909 0.091 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.908 0.092 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.900 0.100 0.000
Z22 Carrier of infectious disease
0.895 0.105 0.000
I05-I09 Chronic rheumatic heart diseases
0.893 0.107 0.000
S80-S89 Injuries to the knee and lower leg
0.893 0.107 0.000
E20-E35 Disorders of other endocrine glands
0.892 0.108 0.000
E66.9 Obesity, unspecified
0.892 0.108 0.000
K70-K77 Diseases of liver
0.890 0.110 0.000
G93.3 Postviral fatigue syndrome
0.888 0.112 0.000
M48 Other spondylopathies
0.888 0.112 0.000
R21 Rash and other nonspecific skin eruption
0.881 0.119 0.000
Chapter X Diseases of the respiratory system
0.880 0.120 0.000
I69 Sequelae of cerebrovascular disease
0.874 0.126 0.000
Z03.8 Observation for other suspected diseases and conditions
0.873 0.127 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.873 0.127 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.872 0.128 0.000
K51 Ulcerative colitis
0.870 0.130 0.000
R06 Abnormalities of breathing
0.867 0.133 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.867 0.133 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.867 0.133 0.000
K82 Other diseases of gallbladder
0.866 0.134 0.000
G81 Hemiplegia
0.866 0.134 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.865 0.135 0.000
E70-E90 Metabolic disorders
0.864 0.136 0.000
K52 Other non-infective gastro-enteritis and colitis
0.861 0.139 0.000
M47.8 Other spondylosis
0.860 0.140 0.000
I45 Other conduction disorders
0.860 0.140 0.000
Z46 Fitting and adjustment of other devices
0.858 0.142 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.854 0.146 0.000
Z60 Problems related to social environment
0.851 0.149 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.851 0.149 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.847 0.153 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.846 0.154 0.000
M13 Other arthritis
0.845 0.155 0.000
G20-G26 Extrapyramidal and movement disorders
0.843 0.157 0.000
E55 Vitamin D deficiency
0.842 0.157 0.000
K76 Other diseases of liver
0.842 0.158 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.839 0.161 0.000
G93.0 Cerebral cysts
0.838 0.162 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.838 0.162 0.000
Z29 Need for other prophylactic measures
0.837 0.163 0.000
M47.9 Spondylosis, unspecified
0.837 0.163 0.000
G47.9 Sleep disorder, unspecified
0.836 0.164 0.000
J20-J22 Other acute lower respiratory infections
0.835 0.165 0.000
M06 Other rheumatoid arthritis
0.835 0.165 0.000
G40 Epilepsy
0.833 0.167 0.000
M65-M68 Disorders of synovium and tendon
0.832 0.168 0.000
G43 Migraine
0.831 0.169 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.829 0.171 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.829 0.171 0.000
M85 Other disorders of bone density and structure
0.829 0.171 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.828 0.172 0.000
R20 Disturbances of skin sensation
0.826 0.174 0.000
R01 Cardiac murmurs and other cardiac sounds
0.825 0.175 0.000
E05.9 Thyrotoxicosis, unspecified
0.824 0.176 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.823 0.177 0.000
Z49 Care involving dialysis
0.821 0.179 0.000
G81.9 Hemiplegia, unspecified
0.817 0.183 0.000
M84 Disorders of continuity of bone
0.817 0.183 0.000
I45.1 Other and unspecified right bundle-branch block
0.814 0.186 0.000
S82 Fracture of lower leg, including ankle
0.813 0.187 0.000
M47.82 Other spondylosis (Cervical region)
0.806 0.194 0.000
Z22.3 Carrier of other specified bacterial diseases
0.806 0.194 0.000
K80.4 Calculus of bile duct with cholecystitis
0.805 0.195 0.000
K83 Other diseases of biliary tract
0.804 0.196 0.000
M91-M94 Chondropathies
0.804 0.196 0.000
M48.0 Spinal stenosis
0.803 0.197 0.000
R00 Abnormalities of heart beat
0.801 0.199 0.000
Z60.2 Living alone
0.798 0.202 0.000
S00-S09 Injuries to the head
0.798 0.202 0.000
M70-M79 Other soft tissue disorders
0.797 0.203 0.000
M25.4 Effusion of joint
0.796 0.204 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.796 0.204 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.795 0.205 0.000
J90-J94 Other diseases of pleura
0.789 0.211 0.000
I08 Multiple valve diseases
0.789 0.211 0.000
I62 Other nontraumatic intracranial haemorrhage
0.787 0.213 0.000
E78.5 Hyperlipidaemia, unspecified
0.787 0.213 0.000
E40-E46 Malnutrition
0.786 0.214 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.786 0.214 0.000
T18 Foreign body in alimentary tract
0.785 0.215 0.000
Chapter V Mental and behavioural disorders
0.783 0.217 0.000
E55.9 Vitamin D deficiency, unspecified
0.783 0.217 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.781 0.219 0.000
R05 Cough
0.781 0.219 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.780 0.220 0.000
J22 Unspecified acute lower respiratory infection
0.780 0.220 0.000
M40-M43 Deforming dorsopathies
0.779 0.221 0.000
M25.5 Pain in joint
0.779 0.221 0.000
S60-S69 Injuries to the wrist and hand
0.778 0.222 0.000
M45 Ankylosing spondylitis
0.777 0.223 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.777 0.223 0.000
Z43.1 Attention to gastrostomy
0.777 0.223 0.000
Chapter VIII Diseases of the ear and mastoid process
0.777 0.223 0.000
T90 Sequelae of injuries of head
0.776 0.224 0.000
S20-S29 Injuries to the thorax
0.775 0.225 0.000
I63.8 Other cerebral infarction
0.775 0.225 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.773 0.227 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.773 0.227 0.000
K35-K38 Diseases of appendix
0.773 0.227 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.771 0.229 0.000
Z04 Examination and observation for other reasons
0.769 0.231 0.000
Chapter XXII Codes for special purposes
0.768 0.232 0.000
Z46.6 Fitting and adjustment of urinary device
0.767 0.233 0.000
M35 Other systemic involvement of connective tissue
0.766 0.234 0.000
K05 Gingivitis and periodontal diseases
0.764 0.236 0.000
Z22.5 Carrier of viral hepatitis
0.764 0.236 0.000
I51 Complications and ill-defined descriptions of heart disease
0.761 0.239 0.000
R06.0 Dyspnoea
0.761 0.239 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.760 0.240 0.000
T93 Sequelae of injuries of lower limb
0.759 0.241 0.000
S50-S59 Injuries to the elbow and forearm
0.756 0.244 0.000
Chapter I Certain infectious and parasitic diseases
0.755 0.245 0.000
M13.9 Arthritis, unspecified
0.755 0.245 0.000
S82.8 Fractures of other parts of lower leg
0.752 0.248 0.000
M81 Osteoporosis without pathological fracture
0.752 0.248 0.000
M25.7 Osteophyte
0.751 0.249 0.000
J93 Pneumothorax
0.750 0.250 0.000
Z63 Other problems related to primary support group, including family circumstances
0.749 0.251 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.749 0.251 0.000
M86-M90 Other osteopathies
0.748 0.252 0.000
Z50.5 Speech therapy
0.748 0.252 0.000
Z42 Follow-up care involving plastic surgery
0.748 0.252 0.000
M06.9 Rheumatoid arthritis, unspecified
0.748 0.252 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.747 0.253 0.000
G96 Other disorders of central nervous system
0.746 0.254 0.000
I44 Atrioventricular and left bundle-branch block
0.746 0.254 0.000
G82 Paraplegia and tetraplegia
0.745 0.255 0.000
Y84.6 Urinary catheterisation
0.745 0.255 0.000
T92 Sequelae of injuries of upper limb
0.745 0.255 0.000
G91 Hydrocephalus
0.744 0.255 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.744 0.256 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.744 0.256 0.000
M21 Other acquired deformities of limbs
0.743 0.257 0.000
M31 Other necrotising vasculopathies
0.743 0.257 0.000
M85.8 Other specified disorders of bone density and structure
0.742 0.258 0.000
Y84.8 Other medical procedures
0.742 0.258 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.741 0.259 0.000
E53 Deficiency of other B group vitamins
0.740 0.260 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.739 0.261 0.000
M05 Seropositive rheumatoid arthritis
0.737 0.263 0.000
Z30 Contraceptive management
0.736 0.264 0.000
R73 Elevated blood glucose level
0.736 0.264 0.000
R01.1 Cardiac murmur, unspecified
0.736 0.264 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.735 0.265 0.000
R00.0 Tachycardia, unspecified
0.735 0.265 0.000
E27 Other disorders of adrenal gland
0.734 0.266 0.000
Q00-Q07 Congenital malformations of the nervous system
0.734 0.266 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.733 0.267 0.000
M23 Internal derangement of knee
0.732 0.268 0.000
G95 Other diseases of spinal cord
0.731 0.269 0.000
I12 Hypertensive renal disease
0.730 0.270 0.000
K51.4 Pseudopolyposis of colon
0.730 0.270 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.729 0.271 0.000
K50 Crohn's disease [regional enteritis]
0.729 0.271 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.729 0.271 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.729 0.271 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.728 0.272 0.000
G43.1 Migraine with aura [classical migraine]
0.728 0.272 0.000
M80 Osteoporosis with pathological fracture
0.727 0.273 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.727 0.273 0.000
M48.02 Spinal stenosis (Cervical region)
0.726 0.274 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.726 0.274 0.000
Z43.3 Attention to colostomy
0.726 0.274 0.000
M25.8 Other specified joint disorders
0.724 0.276 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.724 0.276 0.000
K14 Diseases of tongue
0.723 0.277 0.000
T18.1 Foreign body in oesophagus
0.723 0.277 0.000
I50 Heart failure
0.722 0.278 0.000
J93.9 Pneumothorax, unspecified
0.722 0.278 0.000
Z03.3 Observation for suspected nervous system disorder
0.722 0.278 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.721 0.279 0.000
K82.1 Hydrops of gallbladder
0.721 0.279 0.000
I60 Subarachnoid haemorrhage
0.721 0.279 0.000
K51.9 Ulcerative colitis, unspecified
0.721 0.279 0.000
M25.3 Other instability of joint
0.720 0.280 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.719 0.281 0.000
K11 Diseases of salivary glands
0.719 0.281 0.000
M25.9 Joint disorder, unspecified
0.718 0.282 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.717 0.283 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.717 0.283 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.717 0.283 0.000
G41 Status epilepticus
0.717 0.283 0.000
E06 Thyroiditis
0.716 0.284 0.000
W00-W19 Falls
0.716 0.284 0.000
G47.8 Other sleep disorders
0.715 0.285 0.000
G47.4 Narcolepsy and cataplexy
0.715 0.285 0.000
G47.2 Disorders of the sleep-wake schedule
0.715 0.285 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.715 0.285 0.000
Z40 Prophylactic surgery
0.715 0.285 0.000
G20 Parkinson's disease
0.715 0.285 0.000
R06.5 Mouth breathing
0.715 0.285 0.000
M10 Gout
0.715 0.285 0.000
M46 Other inflammatory spondylopathies
0.714 0.285 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.714 0.286 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.714 0.286 0.000
R47-R49 Symptoms and signs involving speech and voice
0.714 0.286 0.000
Y84.2 Radiological procedure and radiotherapy
0.713 0.287 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
S10-S19 Injuries to the neck
0.713 0.287 0.000
K80.3 Calculus of bile duct with cholangitis
0.713 0.287 0.000
K80.8 Other cholelithiasis
0.713 0.287 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.713 0.287 0.000
S90-S99 Injuries to the ankle and foot
0.712 0.288 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.711 0.289 0.000
B95-B98 Bacterial, viral and other infectious agents
0.710 0.290 0.000
I35 Nonrheumatic aortic valve disorders
0.710 0.290 0.000
W20-W49 Exposure to inanimate mechanical forces
0.710 0.290 0.000
Z03.1 Observation for suspected malignant neoplasm
0.710 0.290 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.709 0.291 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.709 0.291 0.000
I15 Secondary hypertension
0.709 0.291 0.000
I13 Hypertensive heart and renal disease
0.709 0.291 0.000
I11 Hypertensive heart disease
0.709 0.291 0.000
Z41 Procedures for purposes other than remedying health state
0.709 0.291 0.000
R06.2 Wheezing
0.708 0.292 0.000
M47.2 Other spondylosis with radiculopathy
0.707 0.293 0.000
M49 Spondylopathies in diseases classified elsewhere
0.706 0.294 0.000
E22 Hyperfunction of pituitary gland
0.706 0.294 0.000
Z54 Convalescence
0.706 0.294 0.000
Z52 Donors of organs and tissues
0.706 0.294 0.000
Z44 Fitting and adjustment of external prosthetic device
0.706 0.294 0.000
M07 Psoriatic and enteropathic arthropathies
0.705 0.294 0.000
K82.2 Perforation of gallbladder
0.705 0.295 0.000
J09-J18 Influenza and pneumonia
0.705 0.295 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.705 0.295 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.705 0.295 0.000
G90 Disorders of autonomic nervous system
0.705 0.295 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.705 0.295 0.000
G92 Toxic encephalopathy
0.705 0.295 0.000
Z04.8 Examination and observation for other specified reasons
0.704 0.296 0.000
G44 Other headache syndromes
0.703 0.297 0.000
H65-H75 Diseases of middle ear and mastoid
0.703 0.297 0.000
G70-G73 Diseases of myoneural junction and muscle
0.702 0.298 0.000
T79-T79 Certain early complications of trauma
0.701 0.299 0.000
Z34 Supervision of normal pregnancy
0.701 0.299 0.000
Q60-Q64 Congenital malformations of the urinary system
0.701 0.299 0.000
I05 Rheumatic mitral valve diseases
0.700 0.300 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.699 0.301 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.698 0.302 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.698 0.302 0.000
R06.6 Hiccough
0.698 0.302 0.000
J20 Acute bronchitis
0.698 0.302 0.000
Z50.6 Orthoptic training
0.697 0.303 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.697 0.303 0.000
Z50.3 Drug rehabilitation
0.697 0.303 0.000
K52.1 Toxic gastro-enteritis and colitis
0.697 0.303 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.696 0.304 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.696 0.304 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.696 0.304 0.000
Y84.0 Cardiac catheterisation
0.695 0.305 0.000
Z29.1 Prophylactic immunotherapy
0.695 0.305 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.694 0.306 0.000
M34 Systemic sclerosis
0.694 0.306 0.000
M33 Dermatopolymyositis
0.694 0.306 0.000
M32 Systemic lupus erythematosus
0.694 0.306 0.000
M30 Polyarteritis nodosa and related conditions
0.694 0.306 0.000
E61 Deficiency of other nutrient elements
0.693 0.307 0.000
M47.86 Other spondylosis (Lumbar region)
0.693 0.307 0.000
S81 Open wound of lower leg
0.693 0.307 0.000
Z29.2 Other prophylactic chemotherapy
0.692 0.308 0.000
M65 Synovitis and tenosynovitis
0.691 0.309 0.000
I95 Hypotension
0.690 0.310 0.000
Z49.2 Other dialysis
0.690 0.310 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.690 0.310 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.689 0.311 0.000
K82.4 Cholesterolosis of gallbladder
0.689 0.311 0.000
I63.9 Cerebral infarction, unspecified
0.689 0.311 0.000
M25.46 Effusion of joint (Lower leg)
0.688 0.312 0.000
Z28 Immunisation not carried out
0.688 0.312 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.688 0.312 0.000
Z26 Need for immunisation against other single infectious diseases
0.688 0.312 0.000
Z25 Need for immunisation against other single viral diseases
0.688 0.312 0.000
Z24 Need for immunisation against certain single viral diseases
0.688 0.312 0.000
Z23 Need for immunisation against single bacterial diseases
0.688 0.312 0.000
Z20 Contact with and exposure to communicable diseases
0.688 0.312 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.688 0.312 0.000
K05.3 Chronic periodontitis
0.685 0.315 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.685 0.315 0.000
M14 Arthropathies in other diseases classified elsewhere
0.685 0.315 0.000
M12 Other specific arthropathies
0.685 0.315 0.000
M11 Other crystal arthropathies
0.685 0.315 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.685 0.315 0.000
M08 Juvenile arthritis
0.685 0.315 0.000
I45.9 Conduction disorder, unspecified
0.684 0.315 0.000
R00.1 Bradycardia, unspecified
0.684 0.316 0.000
R94 Abnormal results of function studies
0.683 0.317 0.000
I67 Other cerebrovascular diseases
0.683 0.317 0.000
Z33 Pregnant state, incidental
0.683 0.317 0.000
Z35 Supervision of high-risk pregnancy
0.683 0.317 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.682 0.318 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.681 0.319 0.000
M83 Adult osteomalacia
0.681 0.319 0.000
M82 Osteoporosis in diseases classified elsewhere
0.681 0.319 0.000
E67 Other hyperalimentation
0.681 0.319 0.000
E68 Sequelae of hyperalimentation
0.681 0.319 0.000
E65 Localised adiposity
0.681 0.319 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.680 0.319 0.000
G93.9 Disorder of brain, unspecified
0.680 0.320 0.000
G93.7 Reye's syndrome
0.680 0.320 0.000
G93.6 Cerebral oedema
0.680 0.320 0.000
G93.5 Compression of brain
0.680 0.320 0.000
G93.4 Encephalopathy, unspecified
0.680 0.320 0.000
G93.2 Benign intracranial hypertension
0.680 0.320 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.680 0.320 0.000
I33 Acute and subacute endocarditis
0.679 0.321 0.000
Z50.2 Alcohol rehabilitation
0.679 0.321 0.000
R23 Other skin changes
0.678 0.322 0.000
G83 Other paralytic syndromes
0.678 0.322 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.678 0.322 0.000
M47.1 Other spondylosis with myelopathy
0.677 0.323 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.677 0.323 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.675 0.325 0.000
M20 Acquired deformities of fingers and toes
0.674 0.326 0.000
R73.0 Abnormal glucose tolerance test
0.674 0.326 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.673 0.326 0.000
Q50-Q56 Congenital malformations of genital organs
0.673 0.327 0.000
M22 Disorders of patella
0.673 0.327 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.673 0.327 0.000
Z39 Postpartum care and examination
0.672 0.328 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.671 0.329 0.000
G40.8 Other epilepsy
0.671 0.329 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.671 0.329 0.000
G80 Infantile cerebral palsy
0.670 0.330 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.669 0.331 0.000
R06.1 Stridor
0.669 0.331 0.000
Z43.2 Attention to ileostomy
0.668 0.332 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.667 0.333 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.667 0.333 0.000
M25.2 Flail joint
0.667 0.333 0.000
M25.1 Fistula of joint
0.667 0.333 0.000
M25.0 Haemarthrosis
0.667 0.333 0.000
M23.3 Other meniscus derangements
0.667 0.333 0.000
E28 Ovarian dysfunction
0.666 0.334 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.666 0.334 0.000
T66-T78 Other and unspecified effects of external causes
0.665 0.335 0.000
R74 Abnormal serum enzyme levels
0.665 0.335 0.000
K72 Hepatic failure, not elsewhere classified
0.665 0.335 0.000
M94 Other disorders of cartilage
0.664 0.336 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.664 0.336 0.000
E63 Other nutritional deficiencies
0.664 0.336 0.000
E56 Other vitamin deficiencies
0.664 0.336 0.000
E51 Thiamine deficiency
0.664 0.336 0.000
E50 Vitamin A deficiency
0.664 0.336 0.000
E60 Dietary zinc deficiency
0.664 0.336 0.000
E59 Dietary selenium deficiency
0.664 0.336 0.000
E58 Dietary calcium deficiency
0.664 0.336 0.000
E54 Ascorbic acid deficiency
0.664 0.336 0.000
E52 Niacin deficiency [pellagra]
0.664 0.336 0.000
Z65 Problems related to other psychosocial circumstances
0.663 0.336 0.000
Z64 Problems related to certain psychosocial circumstances
0.663 0.336 0.000
Z62 Other problems related to upbringing
0.663 0.336 0.000
Z61 Problems related to negative life events in childhood
0.663 0.336 0.000
Z59 Problems related to housing and economic circumstances
0.663 0.336 0.000
Z58 Problems related to physical environment
0.663 0.336 0.000
Z56 Problems related to employment and unemployment
0.663 0.336 0.000
Z55 Problems related to education and literacy
0.663 0.336 0.000
K37 Unspecified appendicitis
0.662 0.338 0.000
G50 Disorders of trigeminal nerve
0.661 0.339 0.000
K76.6 Portal hypertension
0.661 0.339 0.000
S09 Other and unspecified injuries of head
0.661 0.339 0.000
S32 Fracture of lumbar spine and pelvis
0.661 0.339 0.000
X60-X84 Intentional self-harm
0.660 0.340 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.660 0.340 0.000
K75 Other inflammatory liver diseases
0.660 0.340 0.000
I30 Acute pericarditis
0.660 0.340 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.660 0.340 0.000
Y35-Y36 Legal intervention and operations of war
0.660 0.340 0.000
Y10-Y34 Event of undetermined intent
0.660 0.340 0.000
Y00-Y09 Assault
0.660 0.340 0.000
X85-X99 Assault
0.660 0.340 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.660 0.340 0.000
X50-X57 Overexertion, travel and privation
0.660 0.340 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.660 0.340 0.000
X30-X39 Exposure to forces of nature
0.660 0.340 0.000
X20-X29 Contact with venomous animals and plants
0.660 0.340 0.000
X10-X19 Contact with heat and hot substances
0.660 0.340 0.000
X00-X09 Exposure to smoke, fire and flames
0.660 0.340 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.660 0.340 0.000
W75-W84 Other accidental threats to breathing
0.660 0.340 0.000
W65-W74 Accidental drowning and submersion
0.660 0.340 0.000
W50-W64 Exposure to animate mechanical forces
0.660 0.340 0.000
V98-V99 Other and unspecified transport accidents
0.660 0.340 0.000
V95-V97 Air and space transport accidents
0.660 0.340 0.000
V90-V94 Water transport accidents
0.660 0.340 0.000
V80-V89 Other land transport accidents
0.660 0.340 0.000
V70-V79 Bus occupant injured in transport accident
0.660 0.340 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.660 0.340 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.660 0.340 0.000
V40-V49 Car occupant injured in transport accident
0.660 0.340 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.660 0.340 0.000
V20-V29 Motorcycle rider injured in transport accident
0.660 0.340 0.000
V01-V09 Pedestrian injured in transport accident
0.660 0.340 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.660 0.340 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.659 0.341 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.659 0.341 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.659 0.341 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.659 0.341 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.659 0.341 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.659 0.341 0.000
K83.9 Disease of biliary tract, unspecified
0.659 0.341 0.000
G40.9 Epilepsy, unspecified
0.659 0.341 0.000
R01.0 Benign and innocent cardiac murmurs
0.659 0.341 0.000
I34 Nonrheumatic mitral valve disorders
0.658 0.342 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.658 0.342 0.000
Z10 Routine general health check-up of defined subpopulation
0.658 0.342 0.000
T98 Sequelae of other and unspecified effects of external causes
0.657 0.343 0.000
T95 Sequelae of burns, corrosions and frostbite
0.657 0.343 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.657 0.343 0.000
T91 Sequelae of injuries of neck and trunk
0.657 0.343 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.657 0.343 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.657 0.343 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.657 0.343 0.000
Z45 Adjustment and management of implanted device
0.657 0.343 0.000
E78.8 Other disorders of lipoprotein metabolism
0.656 0.344 0.000
Z50.8 Care involving use of rehabilitation procedures
0.656 0.344 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.655 0.344 0.000
E66.1 Drug-induced obesity
0.655 0.344 0.000
E66.0 Obesity due to excess calories
0.655 0.344 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.655 0.345 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.655 0.345 0.000
Z43.9 Attention to unspecified artificial opening
0.655 0.345 0.000
Z43.8 Attention to other artificial openings
0.655 0.345 0.000
Z43.7 Attention to artificial vagina
0.655 0.345 0.000
Z43.5 Attention to cyctostomy
0.655 0.345 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.655 0.345 0.000
Z43.0 Attention to tracheostomy
0.655 0.345 0.000
M25.51 Pain in joint (Shoulder region)
0.654 0.346 0.000
K86 Other diseases of pancreas
0.654 0.346 0.000
Z31 Procreative management
0.654 0.346 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.652 0.348 0.000
E00 Congenital iodine-deficiency syndrome
0.652 0.348 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.652 0.348 0.000
I52 Other heart disorders in diseases classified elsewhere
0.652 0.348 0.000
I48 Atrial fibrillation and flutter
0.652 0.348 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.652 0.348 0.000
I41 Myocarditis in diseases classified elsewhere
0.652 0.348 0.000
I40 Acute myocarditis
0.652 0.348 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.652 0.348 0.000
I37 Pulmonary valve disorders
0.652 0.348 0.000
I36 Nonrheumatic tricuspid valve disorders
0.652 0.348 0.000
I32 Pericarditis in diseases classified elsewhere
0.652 0.348 0.000
I07 Rheumatic tricuspid valve diseases
0.651 0.349 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.651 0.349 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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