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Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76475900
log Bayes Factor = 15.2634
Chromosome 16   position 59,672,738  (GRCh37) Explore rs76475900 on Ensembl!
Variant rs76475900 is part of Cluster X0122

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
G40-G47 Episodic and paroxysmal disorders
0.997 0.003 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.993 0.007 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.992 0.008 0.000
R30-R39 Symptoms and signs involving the urinary system
0.990 0.010 0.000
L03 Cellulitis
0.987 0.013 0.000
G43 Migraine
0.984 0.016 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.980 0.020 0.000
Chapter XI Diseases of the digestive system
0.979 0.021 0.000
L03.1 Cellulitis of other parts of limb
0.979 0.021 0.000
G43.9 Migraine, unspecified
0.974 0.026 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.974 0.026 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.973 0.027 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.972 0.028 0.000
R33 Retention of urine
0.972 0.028 0.000
I25.1 Atherosclerotic heart disease
0.971 0.029 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.968 0.032 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.960 0.040 0.000
K83 Other diseases of biliary tract
0.959 0.041 0.000
R35 Polyuria
0.959 0.041 0.000
L08 Other local infections of skin and subcutaneous tissue
0.958 0.042 0.000
I05-I09 Chronic rheumatic heart diseases
0.954 0.046 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.952 0.048 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.949 0.051 0.000
G81 Hemiplegia
0.944 0.055 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.941 0.059 0.000
I25.2 Old myocardial infarction
0.935 0.065 0.000
K86 Other diseases of pancreas
0.931 0.069 0.000
I60-I69 Cerebrovascular diseases
0.930 0.070 0.000
Chapter XXI Factors influencing health status and contact with health services
0.928 0.072 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.927 0.073 0.000
G81.9 Hemiplegia, unspecified
0.924 0.076 0.000
M20-M25 Other joint disorders
0.923 0.077 0.000
K80 Cholelithiasis
0.920 0.080 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.918 0.082 0.000
R31 Unspecified haematuria
0.911 0.089 0.000
Q60-Q64 Congenital malformations of the urinary system
0.911 0.089 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.909 0.091 0.000
Chapter VIII Diseases of the ear and mastoid process
0.906 0.094 0.000
M25 Other joint disorders, not elsewhere classified
0.903 0.097 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.894 0.106 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.893 0.107 0.000
S60-S69 Injuries to the wrist and hand
0.888 0.112 0.000
I08 Multiple valve diseases
0.886 0.114 0.000
K83.1 Obstruction of bile duct
0.885 0.115 0.000
K83.8 Other specified diseases of biliary tract
0.882 0.118 0.000
I22 Subsequent myocardial infarction
0.882 0.118 0.000
I30-I52 Other forms of heart disease
0.882 0.118 0.000
I21 Acute myocardial infarction
0.878 0.122 0.000
K86.1 Other chronic pancreatitis
0.875 0.125 0.000
Chapter XX External causes of morbidity and mortality
0.871 0.129 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.869 0.131 0.000
Q61 Cystic kidney disease
0.868 0.132 0.000
Z13 Special screening examination for other diseases and disorders
0.868 0.132 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.868 0.132 0.000
M80-M85 Disorders of bone density and structure
0.864 0.136 0.000
Z02 Examination and encounter for administrative purposes
0.860 0.140 0.000
G47 Sleep disorders
0.858 0.142 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.854 0.146 0.000
L89 Decubitus ulcer
0.846 0.154 0.000
M50-M54 Other dorsopathies
0.844 0.156 0.000
M25.5 Pain in joint
0.842 0.158 0.000
Z02.8 Other examinations for administrative purposes
0.836 0.164 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.835 0.164 0.000
K50-K52 Noninfective enteritis and colitis
0.834 0.166 0.000
O20 Haemorrhage in early pregnancy
0.832 0.168 0.000
Chapter XXII Codes for special purposes
0.832 0.168 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.830 0.170 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.826 0.174 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.823 0.177 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.822 0.178 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.817 0.183 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.812 0.188 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.809 0.191 0.000
I25.3 Aneurysm of heart
0.808 0.192 0.000
G20-G26 Extrapyramidal and movement disorders
0.808 0.192 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.806 0.194 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.805 0.195 0.000
L03.8 Cellulitis of other sites
0.804 0.196 0.000
H65-H75 Diseases of middle ear and mastoid
0.798 0.202 0.000
I44 Atrioventricular and left bundle-branch block
0.796 0.204 0.000
O00-O08 Pregnancy with abortive outcome
0.794 0.206 0.000
I67 Other cerebrovascular diseases
0.791 0.209 0.000
S70-S79 Injuries to the hip and thigh
0.791 0.209 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.789 0.211 0.000
H90-H95 Other disorders of ear
0.788 0.212 0.000
R27 Other lack of coordination
0.788 0.212 0.000
S40-S49 Injuries to the shoulder and upper arm
0.788 0.212 0.000
I60 Subarachnoid haemorrhage
0.787 0.213 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.786 0.214 0.000
K08 Other disorders of teeth and supporting structures
0.785 0.215 0.000
G44 Other headache syndromes
0.785 0.215 0.000
S50-S59 Injuries to the elbow and forearm
0.785 0.215 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.783 0.217 0.000
M25.56 Pain in joint (Lower leg)
0.782 0.218 0.000
K85 Acute pancreatitis
0.782 0.218 0.000
M35 Other systemic involvement of connective tissue
0.781 0.219 0.000
M45-M49 Spondylopathies
0.781 0.219 0.000
Q61.3 Polycystic kidney, unspecified
0.779 0.221 0.000
G90-G99 Other disorders of the nervous system
0.778 0.221 0.000
G45.4 Transient global amnesia
0.777 0.223 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.776 0.224 0.000
I31 Other diseases of pericardium
0.775 0.225 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.774 0.226 0.000
I25.5 Ischaemic cardiomyopathy
0.774 0.226 0.000
K51 Ulcerative colitis
0.773 0.227 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.773 0.227 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.772 0.228 0.000
I07 Rheumatic tricuspid valve diseases
0.771 0.228 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.771 0.229 0.000
G70-G73 Diseases of myoneural junction and muscle
0.771 0.229 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.771 0.229 0.000
G80 Infantile cerebral palsy
0.770 0.230 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.770 0.230 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.770 0.230 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.769 0.231 0.000
G40 Epilepsy
0.768 0.232 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.768 0.232 0.000
K83.0 Cholangitis
0.767 0.233 0.000
M25.9 Joint disorder, unspecified
0.767 0.233 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.765 0.235 0.000
L60-L75 Disorders of skin appendages
0.764 0.236 0.000
R39 Other symptoms and signs involving the urinary system
0.763 0.237 0.000
L03.3 Cellulitis of trunk
0.762 0.238 0.000
I05 Rheumatic mitral valve diseases
0.761 0.239 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.759 0.241 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.758 0.242 0.000
Q80-Q89 Other congenital malformations
0.757 0.243 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.756 0.244 0.000
Z13.9 Special screening examination, unspecified
0.756 0.244 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.755 0.245 0.000
I21.9 Acute myocardial infarction, unspecified
0.754 0.246 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.754 0.246 0.000
G47.3 Sleep apnoea
0.753 0.247 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.752 0.248 0.000
I80 Phlebitis and thrombophlebitis
0.752 0.248 0.000
S64 Injury of nerves at wrist and hand level
0.752 0.248 0.000
O80-O84 Delivery
0.750 0.250 0.000
I69 Sequelae of cerebrovascular disease
0.750 0.250 0.000
R25 Abnormal involuntary movements
0.750 0.250 0.000
I08.0 Disorders of both mitral and aortic valves
0.749 0.251 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.748 0.251 0.000
M25.4 Effusion of joint
0.746 0.254 0.000
M05-M14 Inflammatory polyarthropathies
0.746 0.254 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.745 0.255 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.745 0.255 0.000
Q61.2 Polycystic kidney, adult type
0.745 0.255 0.000
L90 Atrophic disorders of skin
0.743 0.257 0.000
R47-R49 Symptoms and signs involving speech and voice
0.738 0.262 0.000
M54 Dorsalgia
0.738 0.262 0.000
I45 Other conduction disorders
0.738 0.262 0.000
O20.0 Threatened abortion
0.736 0.264 0.000
I20 Angina pectoris
0.735 0.265 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.733 0.267 0.000
K81 Cholecystitis
0.732 0.268 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.732 0.268 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.732 0.268 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.732 0.268 0.000
S20-S29 Injuries to the thorax
0.730 0.270 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.730 0.270 0.000
O02 Other abnormal products of conception
0.729 0.271 0.000
S10-S19 Injuries to the neck
0.729 0.271 0.000
S62 Fracture at wrist and hand level
0.729 0.271 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.727 0.272 0.000
H90 Conductive and sensorineural hearing loss
0.727 0.273 0.000
G30-G32 Other degenerative diseases of the nervous system
0.726 0.274 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.726 0.274 0.000
M50 Cervical disk disorders
0.723 0.277 0.000
M81 Osteoporosis without pathological fracture
0.722 0.278 0.000
G43.1 Migraine with aura [classical migraine]
0.721 0.279 0.000
L84 Corns and callosities
0.719 0.281 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
L10-L14 Bullous disorders
0.716 0.284 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.716 0.284 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.716 0.284 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.715 0.285 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.715 0.285 0.000
G41 Status epilepticus
0.715 0.285 0.000
I61 Intracerebral haemorrhage
0.715 0.285 0.000
L04 Acute lymphadenitis
0.714 0.286 0.000
L01 Impetigo
0.714 0.286 0.000
L00 Staphylococcal scalded skin syndrome
0.714 0.286 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.713 0.287 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.712 0.288 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.712 0.288 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.711 0.289 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.711 0.289 0.000
T00-T07 Injuries involving multiple body regions
0.711 0.289 0.000
S80-S89 Injuries to the knee and lower leg
0.711 0.289 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.711 0.289 0.000
T79-T79 Certain early complications of trauma
0.710 0.290 0.000
R36 Urethral discharge
0.710 0.290 0.000
R34 Anuria and oliguria
0.710 0.290 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.710 0.290 0.000
M25.54 Pain in joint (Hand)
0.709 0.291 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.709 0.291 0.000
G82 Paraplegia and tetraplegia
0.708 0.291 0.000
T81 Complications of procedures, not elsewhere classified
0.707 0.293 0.000
L03.2 Cellulitis of face
0.707 0.293 0.000
O23 Infections of genito-urinary tract in pregnancy
0.707 0.293 0.000
K86.9 Disease of pancreas, unspecified
0.707 0.293 0.000
G43.8 Other migraine
0.705 0.294 0.000
G43.3 Complicated migraine
0.705 0.294 0.000
G43.2 Status migrainosus
0.705 0.294 0.000
G43.0 Migraine without aura [common migraine]
0.705 0.294 0.000
Q00-Q07 Congenital malformations of the nervous system
0.705 0.294 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.705 0.295 0.000
K86.3 Pseudocyst of pancreas
0.705 0.295 0.000
Y95 Nosocomial condition
0.705 0.295 0.000
M86-M90 Other osteopathies
0.704 0.296 0.000
G83 Other paralytic syndromes
0.704 0.296 0.000
M70-M79 Other soft tissue disorders
0.704 0.296 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.703 0.297 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.703 0.297 0.000
I31.3 Pericardial effusion (noninflammatory)
0.702 0.298 0.000
I24 Other acute ischaemic heart diseases
0.701 0.299 0.000
K70-K77 Diseases of liver
0.700 0.300 0.000
R74 Abnormal serum enzyme levels
0.699 0.301 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.699 0.301 0.000
Q61.0 Congenital single renal cyst
0.699 0.301 0.000
L20-L30 Dermatitis and eczema
0.699 0.301 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.698 0.302 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.698 0.302 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.698 0.302 0.000
L94 Other localised connective tissue disorders
0.698 0.302 0.000
L93 Lupus erythematosus
0.698 0.302 0.000
L87 Transepidermal elimination disorders
0.698 0.302 0.000
L88 Pyoderma gangrenosum
0.698 0.302 0.000
L86 Keratoderma in diseases classified elsewhere
0.698 0.302 0.000
L83 Acanthosis nigricans
0.698 0.302 0.000
L80 Vitiligo
0.698 0.302 0.000
L05 Pilonidal cyst
0.698 0.302 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.698 0.302 0.000
M91-M94 Chondropathies
0.697 0.303 0.000
M60-M63 Disorders of muscles
0.697 0.303 0.000
M00-M03 Infectious arthropathies
0.697 0.303 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.697 0.303 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.697 0.303 0.000
I67.9 Cerebrovascular disease, unspecified
0.696 0.304 0.000
K80.4 Calculus of bile duct with cholecystitis
0.695 0.305 0.000
G37 Other demyelinating diseases of central nervous system
0.695 0.305 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.695 0.305 0.000
M80 Osteoporosis with pathological fracture
0.694 0.306 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.694 0.306 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.694 0.306 0.000
Q50-Q56 Congenital malformations of genital organs
0.694 0.306 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.694 0.306 0.000
Q35-Q37 Cleft lip and cleft palate
0.694 0.306 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.694 0.306 0.000
Chapter VII Diseases of the eye and adnexa
0.694 0.306 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.693 0.307 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.693 0.307 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.692 0.308 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.690 0.310 0.000
K80.8 Other cholelithiasis
0.690 0.310 0.000
O30 Multiple gestation
0.689 0.311 0.000
I36 Nonrheumatic tricuspid valve disorders
0.689 0.311 0.000
K51.9 Ulcerative colitis, unspecified
0.688 0.312 0.000
T87 Complications peculiar to reattachment and amputation
0.688 0.312 0.000
T86 Failure and rejection of transplanted organs and tissues
0.688 0.312 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.688 0.312 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.688 0.312 0.000
K83.9 Disease of biliary tract, unspecified
0.688 0.312 0.000
K83.5 Biliary cyst
0.688 0.312 0.000
K83.4 Spasm of sphincter of Oddi
0.688 0.312 0.000
K83.3 Fistula of bile duct
0.688 0.312 0.000
K83.2 Perforation of bile duct
0.688 0.312 0.000
L08.1 Erythrasma
0.686 0.313 0.000
L08.0 Pyoderma
0.686 0.313 0.000
O21 Excessive vomiting in pregnancy
0.686 0.314 0.000
Z50 Care involving use of rehabilitation procedures
0.686 0.314 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.685 0.315 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.685 0.315 0.000
I87 Other disorders of veins
0.685 0.315 0.000
M24 Other specific joint derangements
0.685 0.315 0.000
I09 Other rheumatic heart diseases
0.684 0.316 0.000
I06 Rheumatic aortic valve diseases
0.684 0.316 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.684 0.316 0.000
O02.1 Missed abortion
0.683 0.317 0.000
I44.1 Atrioventricular block, second degree
0.683 0.317 0.000
O85-O92 Complications predominantly related to the puerperium
0.683 0.317 0.000
K11 Diseases of salivary glands
0.682 0.318 0.000
H65 Nonsuppurative otitis media
0.682 0.318 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.680 0.320 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.680 0.320 0.000
L98.5 Mucinosis of skin
0.680 0.320 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.680 0.320 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.680 0.320 0.000
L98.1 Factitial dermatitis
0.680 0.320 0.000
K00 Disorders of tooth development and eruption
0.679 0.321 0.000
L60 Nail disorders
0.679 0.321 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.678 0.322 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.678 0.322 0.000
G81.1 Spastic hemiplegia
0.677 0.323 0.000
G81.0 Flaccid hemiplegia
0.677 0.323 0.000
M21 Other acquired deformities of limbs
0.676 0.324 0.000
H90.2 Conductive hearing loss, unspecified
0.676 0.324 0.000
L89.1 Stage II decubitus ulcer
0.675 0.325 0.000
L90.0 Lichen sclerosus et atrophicus
0.673 0.327 0.000
K12 Stomatitis and related lesions
0.672 0.327 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.672 0.328 0.000
K82 Other diseases of gallbladder
0.670 0.330 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.670 0.330 0.000
L98.0 Pyogenic granuloma
0.670 0.330 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.670 0.330 0.000
M22 Disorders of patella
0.669 0.331 0.000
K86.2 Cyst of pancreas
0.668 0.332 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.667 0.333 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.667 0.333 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.667 0.333 0.000
Q63 Other congenital malformations of kidney
0.666 0.334 0.000
S90-S99 Injuries to the ankle and foot
0.665 0.335 0.000
W20-W49 Exposure to inanimate mechanical forces
0.665 0.335 0.000
Z03.8 Observation for other suspected diseases and conditions
0.664 0.336 0.000
I44.7 Left bundle-branch block, unspecified
0.663 0.337 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.662 0.338 0.000
M34 Systemic sclerosis
0.662 0.338 0.000
M33 Dermatopolymyositis
0.662 0.338 0.000
M32 Systemic lupus erythematosus
0.662 0.338 0.000
M30 Polyarteritis nodosa and related conditions
0.662 0.338 0.000
L50-L54 Urticaria and erythema
0.662 0.338 0.000
K07 Dentofacial anomalies [including malocclusion]
0.660 0.340 0.000
K80.3 Calculus of bile duct with cholangitis
0.660 0.340 0.000
L91 Hypertrophic disorders of skin
0.659 0.341 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.657 0.342 0.000
R27.0 Ataxia, unspecified
0.657 0.343 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.656 0.344 0.000
I20.8 Other forms of angina pectoris
0.656 0.344 0.000
I30 Acute pericarditis
0.655 0.345 0.000
L03.9 Cellulitis, unspecified
0.655 0.345 0.000
M84 Disorders of continuity of bone
0.655 0.345 0.000
M25.8 Other specified joint disorders
0.654 0.346 0.000
Q64 Other congenital malformations of urinary system
0.653 0.347 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.653 0.347 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.653 0.347 0.000
I62 Other nontraumatic intracranial haemorrhage
0.653 0.347 0.000
G25 Other extrapyramidal and movement disorders
0.652 0.348 0.000
O29 Complications of anaesthesia during pregnancy
0.652 0.348 0.000
O28 Abnormal findings on antenatal screening of mother
0.652 0.348 0.000
O24 Diabetes mellitus in pregnancy
0.652 0.348 0.000
O22 Venous complications in pregnancy
0.652 0.348 0.000
O25 Malnutrition in pregnancy
0.652 0.348 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.651 0.349 0.000
Z13.1 Special screening examination for diabetes mellitus
0.651 0.349 0.000
I47 Paroxysmal tachycardia
0.650 0.350 0.000
S64.3 Injury of digital nerve of thumb
0.650 0.350 0.000
M25.3 Other instability of joint
0.647 0.352 0.000
M25.2 Flail joint
0.647 0.352 0.000
M25.1 Fistula of joint
0.647 0.352 0.000
M25.0 Haemarthrosis
0.647 0.352 0.000
S72 Fracture of femur
0.647 0.353 0.000
I44.6 Other and unspecified fascicular block
0.646 0.354 0.000
S68 Traumatic amputation of wrist and hand
0.646 0.354 0.000
R25.3 Fasciculation
0.646 0.354 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.645 0.355 0.000
S60 Superficial injury of wrist and hand
0.645 0.355 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.645 0.355 0.000
L03.0 Cellulitis of finger and toe
0.643 0.357 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.642 0.358 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.641 0.359 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.641 0.359 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.641 0.359 0.000
T82.3 Mechanical complication of other vascular grafts
0.641 0.359 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.641 0.359 0.000
T82.1 Mechanical complication of cardiac electronic device
0.641 0.359 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.641 0.359 0.000
M35.0 Sicca syndrome [Sjogren]
0.641 0.359 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.641 0.359 0.000
I07.1 Tricuspid insufficiency
0.641 0.359 0.000
Z10 Routine general health check-up of defined subpopulation
0.641 0.359 0.000
Z45 Adjustment and management of implanted device
0.640 0.360 0.000
R82 Other abnormal findings in urine
0.639 0.360 0.000
M25.53 Pain in joint (Forearm)
0.639 0.361 0.000
Z50.0 Cardiac rehabilitation
0.639 0.361 0.000
M85 Other disorders of bone density and structure
0.637 0.363 0.000
R73 Elevated blood glucose level
0.637 0.363 0.000
L81 Other disorders of pigmentation
0.637 0.363 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.637 0.363 0.000
M54.3 Sciatica
0.637 0.363 0.000
S69 Other and unspecified injuries of wrist and hand
0.636 0.364 0.000
S67 Crushing injury of wrist and hand
0.636 0.364 0.000
S65 Injury of blood vessels at wrist and hand level
0.636 0.364 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.636 0.364 0.000
Z60 Problems related to social environment
0.635 0.365 0.000
I08.9 Multiple valve disease, unspecified
0.635 0.365 0.000
I08.8 Other multiple valve diseases
0.635 0.365 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.635 0.365 0.000
I33 Acute and subacute endocarditis
0.634 0.366 0.000
M25.46 Effusion of joint (Lower leg)
0.634 0.366 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.633 0.366 0.000
G44.2 Tension-type headache
0.633 0.366 0.000
I38 Endocarditis, valve unspecified
0.633 0.367 0.000
I22.8 Subsequent myocardial infarction of other sites
0.632 0.368 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.632 0.368 0.000
I52 Other heart disorders in diseases classified elsewhere
0.632 0.368 0.000
I48 Atrial fibrillation and flutter
0.632 0.368 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.632 0.368 0.000
I41 Myocarditis in diseases classified elsewhere
0.632 0.368 0.000
I40 Acute myocarditis
0.632 0.368 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.632 0.368 0.000
I37 Pulmonary valve disorders
0.632 0.368 0.000
I32 Pericarditis in diseases classified elsewhere
0.632 0.368 0.000
T66-T78 Other and unspecified effects of external causes
0.632 0.368 0.000
O26.8 Other specified pregnancy-related conditions
0.632 0.368 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.632 0.368 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.630 0.370 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.630 0.370 0.000
T92 Sequelae of injuries of upper limb
0.630 0.370 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.629 0.370 0.000
M48 Other spondylopathies
0.629 0.371 0.000
I49 Other cardiac arrhythmias
0.629 0.371 0.000
O47 False labour
0.628 0.371 0.000
M25.57 Pain in joint (Ankle and foot)
0.628 0.372 0.000
Q24 Other congenital malformations of heart
0.628 0.372 0.000
M31 Other necrotising vasculopathies
0.627 0.372 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.627 0.373 0.000
G93 Other disorders of brain
0.627 0.373 0.000
K05 Gingivitis and periodontal diseases
0.627 0.373 0.000
K65-K67 Diseases of peritoneum
0.627 0.373 0.000
K14 Diseases of tongue
0.626 0.374 0.000
O41 Other disorders of amniotic fluid and membranes
0.626 0.374 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.626 0.374 0.000
R29.6 Tendency to fall, not elsewhere classified
0.625 0.375 0.000
G80.9 Infantile cerebral palsy, unspecified
0.625 0.375 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.625 0.375 0.000
Y35-Y36 Legal intervention and operations of war
0.625 0.375 0.000
Y10-Y34 Event of undetermined intent
0.625 0.375 0.000
Y00-Y09 Assault
0.625 0.375 0.000
X85-X99 Assault
0.625 0.375 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.625 0.375 0.000
X50-X57 Overexertion, travel and privation
0.625 0.375 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.625 0.375 0.000
X30-X39 Exposure to forces of nature
0.625 0.375 0.000
X20-X29 Contact with venomous animals and plants
0.625 0.375 0.000
X10-X19 Contact with heat and hot substances
0.625 0.375 0.000
X00-X09 Exposure to smoke, fire and flames
0.625 0.375 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.625 0.375 0.000
W75-W84 Other accidental threats to breathing
0.625 0.375 0.000
W65-W74 Accidental drowning and submersion
0.625 0.375 0.000
W50-W64 Exposure to animate mechanical forces
0.625 0.375 0.000
V98-V99 Other and unspecified transport accidents
0.625 0.375 0.000
V95-V97 Air and space transport accidents
0.625 0.375 0.000
V90-V94 Water transport accidents
0.625 0.375 0.000
V80-V89 Other land transport accidents
0.625 0.375 0.000
V70-V79 Bus occupant injured in transport accident
0.625 0.375 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.625 0.375 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.625 0.375 0.000
V40-V49 Car occupant injured in transport accident
0.625 0.375 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.625 0.375 0.000
V20-V29 Motorcycle rider injured in transport accident
0.625 0.375 0.000
V01-V09 Pedestrian injured in transport accident
0.625 0.375 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.624 0.376 0.000
S00-S09 Injuries to the head
0.624 0.376 0.000
I86 Varicose veins of other sites
0.624 0.376 0.000
K85.9 Acute pancreatitis, unspecified
0.624 0.376 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.623 0.377 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.623 0.377 0.000
K51.2 Ulcerative (chronic) proctitis
0.623 0.377 0.000
I05.1 Rheumatic mitral insufficiency
0.623 0.377 0.000
R29.4 Clicking hip
0.623 0.377 0.000
R29.3 Abnormal posture
0.623 0.377 0.000
R29.2 Abnormal reflex
0.623 0.377 0.000
R29.1 Meningismus
0.623 0.377 0.000
R29.0 Tetany
0.623 0.377 0.000
H74 Other disorders of middle ear and mastoid
0.623 0.377 0.000
I82 Other venous embolism and thrombosis
0.623 0.377 0.000
Q61.9 Cystic kidney disease, unspecified
0.623 0.377 0.000
Q61.8 Other cystic kidney diseases
0.623 0.377 0.000
Q61.5 Medullary cystic kidney
0.623 0.377 0.000
Q61.4 Renal dysplasia
0.623 0.377 0.000
Q61.1 Polycystic kidney, infantile type
0.623 0.377 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.622 0.378 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.622 0.378 0.000
Z13.5 Special screening examination for eye and ear disorders
0.622 0.378 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.622 0.378 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.622 0.378 0.000
Z13.2 Special screening examination for nutritional disorders
0.622 0.378 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.622 0.378 0.000
G45.3 Amaurosis fugax
0.622 0.378 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.622 0.378 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.622 0.378 0.000
G45.0 Vertebro-basilar artery syndrome
0.622 0.378 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.622 0.378 0.000
W00-W19 Falls
0.622 0.378 0.000
M25.7 Osteophyte
0.621 0.379 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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