TreeWAS – [I25.1] Atherosclerotic heart disease

TreeWAS

Variant clusters

Hospitalization Episode Statistics (HES)

Genetic variants: 36,212

Diagnostic terms: × 19,155

Association results: = 693,640,860

Self-Reported Statistics (SRS)

Genetic variants: 28,458

Diagnostic terms: × 474

Association results: = 13,489,092

Frequently Asked Questions

Variant effects

Click on a variant to see its association results.

Download this figure in format

Genome-wide Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Results table

Variant	Risk posterior probability	No effect posterior probability	Protective posterior probability
rs55730499 lBF = `430.193` Chr`6` : `161,005,610`	1.000	0.000	0.000
rs10455872 lBF = `427.757` Chr`6` : `161,010,118`	1.000	0.000	0.000
rs74617384 lBF = `405.131` Chr`6` : `160,997,118`	1.000	0.000	0.000
rs1333042 lBF = `395.398` Chr`9` : `22,103,813`	1.000	0.000	0.000
rs7866503 lBF = `386.896` Chr`9` : `22,091,924`	1.000	0.000	0.000
rs2891168 lBF = `383.279` Chr`9` : `22,098,619`	1.000	0.000	0.000
rs10757274 lBF = `379.837` Chr`9` : `22,096,055`	1.000	0.000	0.000
rs4977574 lBF = `376.576` Chr`9` : `22,098,574`	1.000	0.000	0.000
rs1333047 lBF = `375.052` Chr`9` : `22,124,504`	1.000	0.000	0.000
rs10738607 lBF = `371.077` Chr`9` : `22,088,094`	1.000	0.000	0.000
rs1333048 lBF = `369.305` Chr`9` : `22,125,347`	1.000	0.000	0.000
rs944797 lBF = `364.833` Chr`9` : `22,115,286`	1.000	0.000	0.000
rs10757272 lBF = `363.174` Chr`9` : `22,088,260`	1.000	0.000	0.000
rs10733376 lBF = `361.867` Chr`9` : `22,114,469`	1.000	0.000	0.000
rs1333049 lBF = `356.271` Chr`9` : `22,125,503`	1.000	0.000	0.000
rs10757278 lBF = `355.344` Chr`9` : `22,124,477`	1.000	0.000	0.000
rs2383207 lBF = `354.618` Chr`9` : `22,115,959`	0.000	0.000	1.000
rs1537370 lBF = `339.752` Chr`9` : `22,084,310`	1.000	0.000	0.000
rs6475606 lBF = `331.139` Chr`9` : `22,081,850`	1.000	0.000	0.000
rs10757269 lBF = `323.969` Chr`9` : `22,072,264`	1.000	0.000	0.000
rs10217586 lBF = `308.866` Chr`9` : `22,121,349`	1.000	0.000	0.000
rs2315065 lBF = `275.304` Chr`6` : `161,108,144`	1.000	0.000	0.000
rs4252185 lBF = `259.415` Chr`6` : `161,123,451`	1.000	0.000	0.000
rs1333040 lBF = `229.258` Chr`9` : `22,083,404`	0.000	0.000	1.000
rs9457925 lBF = `223.212` Chr`6` : `160,848,743`	1.000	0.000	0.000
rs429358 lBF = `222.835` Chr`19` : `45,411,941`	1.000	0.000	0.000
rs3798220 lBF = `217.284` Chr`6` : `160,961,137`	1.000	0.000	0.000
rs117733303 lBF = `216.685` Chr`6` : `160,922,870`	1.000	0.000	0.000
rs186696265 lBF = `205.379` Chr`6` : `161,111,700`	1.000	0.000	0.000
rs3217992 lBF = `200.854` Chr`9` : `22,003,223`	1.000	0.000	0.000
rs4420638 lBF = `199.322` Chr`19` : `45,422,946`	1.000	0.000	0.000
rs56131196 lBF = `198.195` Chr`19` : `45,422,846`	1.000	0.000	0.000
rs6857 lBF = `185.788` Chr`19` : `45,392,254`	1.000	0.000	0.000
rs10080815 lBF = `180.562` Chr`6` : `160,687,412`	1.000	0.000	0.000
rs4977756 lBF = `180.502` Chr`9` : `22,068,652`	0.000	0.000	1.000
rs2157719 lBF = `171.627` Chr`9` : `22,033,366`	0.000	0.000	1.000
rs1333037 lBF = `168.921` Chr`9` : `22,040,765`	1.000	0.000	0.000
rs7865618 lBF = `166.125` Chr`9` : `22,031,005`	0.000	0.000	1.000
rs769449 lBF = `166.029` Chr`19` : `45,410,002`	1.000	0.000	0.000
rs16891156 lBF = `160.905` Chr`6` : `160,608,804`	1.000	0.000	0.000
rs1063192 lBF = `160.304` Chr`9` : `22,003,367`	0.000	0.000	1.000
rs1412829 lBF = `154.353` Chr`9` : `22,043,926`	0.000	0.000	1.000
rs564398 lBF = `152.203` Chr`9` : `22,029,547`	0.000	0.000	1.000
rs10965219 lBF = `150.789` Chr`9` : `22,053,687`	1.000	0.000	0.000
rs7874604 lBF = `150.563` Chr`9` : `22,054,690`	1.000	0.000	0.000
rs10965215 lBF = `149.273` Chr`9` : `22,029,445`	1.000	0.000	0.000
rs2151280 lBF = `148.877` Chr`9` : `22,034,719`	1.000	0.000	0.000
rs3184504 lBF = `147.788` Chr`12` : `111,884,608`	1.000	0.000	0.000
rs653178 lBF = `141.209` Chr`12` : `112,007,756`	1.000	0.000	0.000
rs2075650 lBF = `139.935` Chr`19` : `45,395,619`	1.000	0.000	0.000
rs4299376 lBF = `139.793` Chr`2` : `44,072,576`	0.000	0.000	1.000
rs597808 lBF = `138.181` Chr`12` : `111,973,358`	0.000	0.000	1.000
rs7137828 lBF = `136.212` Chr`12` : `111,932,800`	0.000	0.000	1.000
rs10774625 lBF = `134.733` Chr`12` : `111,910,219`	1.000	0.000	0.000
rs7310615 lBF = `134.377` Chr`12` : `111,865,049`	0.000	0.000	1.000
rs4766578 lBF = `133.156` Chr`12` : `111,904,371`	0.000	0.000	1.000
rs615552 lBF = `132.45` Chr`9` : `22,026,077`	0.000	0.000	1.000
rs7412 lBF = `130.772` Chr`19` : `45,412,079`	0.000	0.000	1.000
rs1065853 lBF = `130.32` Chr`19` : `45,413,233`	0.000	0.000	1.000
rs629301 lBF = `128.409` Chr`1` : `109,818,306`	0.000	0.000	1.000
rs12740374 lBF = `128.264` Chr`1` : `109,817,590`	0.000	0.000	1.000
rs646776 lBF = `128.214` Chr`1` : `109,818,530`	0.000	0.000	1.000
rs660240 lBF = `127.963` Chr`1` : `109,817,838`	0.000	0.000	1.000
rs4245791 lBF = `127.229` Chr`2` : `44,074,431`	1.000	0.000	0.000
rs523096 lBF = `126.227` Chr`9` : `22,019,129`	0.000	0.000	1.000
rs602633 lBF = `124.913` Chr`1` : `109,821,511`	0.000	0.000	1.000
rs2282143 lBF = `124.222` Chr`6` : `160,557,643`	1.000	0.000	0.000
rs7528419 lBF = `124.033` Chr`1` : `109,817,192`	0.000	0.000	1.000
rs6544713 lBF = `121.649` Chr`2` : `44,073,881`	1.000	0.000	0.000
rs599839 lBF = `117.967` Chr`1` : `109,822,166`	0.000	0.000	1.000
rs10774624 lBF = `108.174` Chr`12` : `111,833,788`	0.000	0.000	1.000
rs59007384 lBF = `103.247` Chr`19` : `45,396,665`	1.000	0.000	0.000
rs157582 lBF = `98.5206` Chr`19` : `45,396,219`	1.000	0.000	0.000
rs157581 lBF = `96.9021` Chr`19` : `45,395,714`	1.000	0.000	0.000
rs573687 lBF = `96.1061` Chr`9` : `22,011,642`	0.000	0.000	1.000
rs74625856 lBF = `95.8612` Chr`6` : `161,313,619`	1.000	0.000	0.000
rs11065979 lBF = `94.2904` Chr`12` : `112,059,557`	1.000	0.000	0.000
rs3731257 lBF = `90.8856` Chr`9` : `21,966,221`	1.000	0.000	0.000
rs11065987 lBF = `90.6309` Chr`12` : `112,072,424`	1.000	0.000	0.000
rs1810126 lBF = `84.9249` Chr`6` : `160,872,151`	1.000	0.000	0.000
rs4709408 lBF = `84.0955` Chr`6` : `160,625,231`	1.000	0.000	0.000
rs2048327 lBF = `83.1979` Chr`6` : `160,863,532`	1.000	0.000	0.000
rs2292334 lBF = `81.8209` Chr`6` : `160,858,188`	1.000	0.000	0.000
rs61271866 lBF = `80.5256` Chr`9` : `21,997,015`	0.000	0.000	1.000
rs17630235 lBF = `80.0182` Chr`12` : `112,591,686`	1.000	0.000	0.000
rs6511720 lBF = `79.2472` Chr`19` : `11,202,306`	0.000	0.000	1.000
rs142130958 lBF = `78.6315` Chr`19` : `11,190,652`	0.000	0.000	1.000
rs55791371 lBF = `78.5581` Chr`19` : `11,188,153`	0.000	0.000	1.000
rs9349379 lBF = `78.4035` Chr`6` : `12,903,957`	1.000	0.000	0.000
rs112374545 lBF = `78.2181` Chr`19` : `11,188,899`	0.000	0.000	1.000
rs17696736 lBF = `77.5307` Chr`12` : `112,486,818`	1.000	0.000	0.000
rs56289821 lBF = `77.2625` Chr`19` : `11,188,247`	0.000	0.000	1.000
rs11066301 lBF = `73.3256` Chr`12` : `112,871,372`	1.000	0.000	0.000
rs3731239 lBF = `69.4018` Chr`9` : `21,974,218`	0.000	0.000	1.000
Affx-4052417 lBF = `65.1564` Chr`1` : `109,817,245`	0.000	0.000	1.000
rs4766897 lBF = `64.6713` Chr`12` : `112,179,471`	1.000	0.000	0.000
rs3902354 lBF = `63.71` Chr`1` : `109,819,296`	1.000	0.000	0.000
rs3918226 lBF = `61.7604` Chr`7` : `150,690,176`	1.000	0.000	0.000
rs6657811 lBF = `61.5013` Chr`1` : `109,807,283`	0.000	0.000	1.000
rs1265564 lBF = `58.6971` Chr`12` : `111,708,458`	1.000	0.000	0.000
rs445925 lBF = `54.8576` Chr`19` : `45,415,640`	0.000	0.000	1.000
rs28929474 lBF = `54.4847` Chr`14` : `94,844,947`	0.000	0.000	1.000
rs112635299 lBF = `54.2277` Chr`14` : `94,838,142`	0.000	0.000	1.000
rs11330240 lBF = `53.4098` Chr`15` : `91,428,521`	1.000	0.000	0.000
rs7497304 lBF = `53.3212` Chr`15` : `91,429,176`	1.000	0.000	0.000
rs17514846 lBF = `52.1536` Chr`15` : `91,416,550`	1.000	0.000	0.000
rs11591147 lBF = `49.3655` Chr`1` : `55,505,647`	0.000	0.000	1.000
rs79570361 lBF = `48.293` Chr`6` : `161,170,855`	1.000	0.000	0.000
rs6935921 lBF = `47.243` Chr`6` : `161,108,536`	0.000	0.000	1.000
rs2521501 lBF = `46.6564` Chr`15` : `91,437,388`	1.000	0.000	0.000
rs932925 lBF = `46.5123` Chr`6` : `160,719,741`	1.000	0.000	0.000
rs157580 lBF = `46.2551` Chr`19` : `45,395,266`	0.000	0.000	1.000
rs3120139 lBF = `45.6848` Chr`6` : `160,741,622`	1.000	0.000	0.000
rs1332844 lBF = `43.8712` Chr`6` : `12,889,004`	0.000	0.000	1.000
rs55754459 lBF = `43.0914` Chr`6` : `161,551,176`	1.000	0.000	0.000
rs2297374 lBF = `43.0286` Chr`6` : `160,575,985`	0.000	0.000	1.000
rs28451064 lBF = `42.9569` Chr`21` : `35,593,827`	1.000	0.000	0.000
rs62556547 lBF = `41.6654` Chr`9` : `22,019,156`	0.000	0.000	1.000
rs4714955 lBF = `41.3295` Chr`6` : `12,903,435`	0.000	0.000	1.000
rs9369640 lBF = `41.0792` Chr`6` : `12,901,441`	0.000	0.000	1.000
rs4932370 lBF = `40.05` Chr`15` : `91,404,705`	1.000	0.000	0.000
rs11668477 lBF = `39.7389` Chr`19` : `11,195,030`	0.000	0.000	1.000
rs2228671 lBF = `38.6156` Chr`19` : `11,210,912`	0.000	0.000	1.000
rs11577931 lBF = `38.4581` Chr`1` : `109,820,884`	0.000	0.000	1.000
rs2677738 lBF = `37.343` Chr`15` : `91,441,673`	0.000	0.000	1.000
rs12526453 lBF = `36.5825` Chr`6` : `12,927,544`	0.000	0.000	1.000
rs1443844 lBF = `35.8627` Chr`6` : `160,574,802`	0.000	0.000	1.000
rs9381462 lBF = `35.1971` Chr`6` : `12,873,775`	0.000	0.000	1.000
rs2954038 lBF = `34.2663` Chr`8` : `126,507,389`	1.000	0.000	0.000
rs12215208 lBF = `34.0802` Chr`6` : `12,850,294`	1.000	0.000	0.000
rs112875651 lBF = `33.8974` Chr`8` : `126,506,694`	0.000	0.000	1.000
rs3798164 lBF = `32.9355` Chr`6` : `160,575,202`	0.000	0.000	1.000
rs2107595 lBF = `32.9202` Chr`7` : `19,049,388`	1.000	0.000	0.000
rs35700460 lBF = `32.4639` Chr`1` : `222,811,407`	1.000	0.000	0.000
rs17321515 lBF = `32.222` Chr`8` : `126,486,409`	0.000	0.000	1.000
rs17465637 lBF = `32.1863` Chr`1` : `222,823,529`	0.000	0.000	1.000
rs2291832 lBF = `31.9857` Chr`1` : `222,826,481`	0.000	0.000	1.000
rs2954029 lBF = `31.8759` Chr`8` : `126,490,972`	0.000	0.000	1.000
rs2133189 lBF = `31.4381` Chr`1` : `222,814,442`	0.000	0.000	1.000
rs2954021 lBF = `31.369` Chr`8` : `126,482,077`	0.000	0.000	1.000
rs7254892 lBF = `30.0759` Chr`19` : `45,389,596`	0.000	0.000	1.000
rs9982601 lBF = `30.0006` Chr`21` : `35,599,128`	1.000	0.000	0.000
rs1561198 lBF = `29.5067` Chr`2` : `85,809,989`	1.000	0.000	0.000
rs1169288 lBF = `29.3975` Chr`12` : `121,416,650`	1.000	0.000	0.000
rs1078004 lBF = `29.0108` Chr`2` : `85,769,711`	1.000	0.000	0.000
rs2954020 lBF = `28.9243` Chr`8` : `126,481,952`	1.000	0.000	0.000
rs12940887 lBF = `28.7338` Chr`17` : `47,402,807`	1.000	0.000	0.000
rs10176176 lBF = `28.6971` Chr`2` : `85,762,048`	1.000	0.000	0.000
rs146534110 lBF = `28.6815` Chr`6` : `160,578,069`	1.000	0.000	0.000
rs57301765 lBF = `28.5048` Chr`7` : `19,052,733`	1.000	0.000	0.000
rs680091 lBF = `28.1368` Chr`10` : `44,738,932`	0.000	0.000	1.000
rs9970807 lBF = `28.0957` Chr`1` : `56,965,664`	0.000	0.000	1.000
rs412522 lBF = `28.067` Chr`6` : `160,727,102`	1.000	0.000	0.000
rs17114046 lBF = `27.978` Chr`1` : `56,966,350`	0.000	0.000	1.000
rs61075980 lBF = `27.6065` Chr`4` : `148,374,767`	1.000	0.000	0.000
rs2980879 lBF = `27.5408` Chr`8` : `126,481,475`	0.000	0.000	1.000
rs2954033 lBF = `27.3604` Chr`8` : `126,493,746`	1.000	0.000	0.000
rs2238151 lBF = `27.2496` Chr`12` : `112,211,833`	0.000	0.000	1.000
rs41289512 lBF = `27.1631` Chr`19` : `45,351,516`	1.000	0.000	0.000
rs494207 lBF = `27.0929` Chr`10` : `44,741,256`	0.000	0.000	1.000
rs7568458 lBF = `27.0882` Chr`2` : `85,788,175`	1.000	0.000	0.000
rs1704223 lBF = `27.0702` Chr`10` : `44,677,014`	0.000	0.000	1.000
rs6841581 lBF = `27.0081` Chr`4` : `148,401,190`	1.000	0.000	0.000
rs1878406 lBF = `26.5327` Chr`4` : `148,393,664`	1.000	0.000	0.000
rs7173743 lBF = `26.4991` Chr`15` : `79,141,784`	0.000	0.000	1.000
rs6842241 lBF = `26.3443` Chr`4` : `148,400,819`	1.000	0.000	0.000
rs12721109 lBF = `26.2199` Chr`19` : `45,447,221`	0.000	0.000	1.000
rs67180937 lBF = `25.5728` Chr`1` : `222,823,743`	1.000	0.000	0.000
rs2624681 lBF = `25.5143` Chr`10` : `44,677,301`	0.000	0.000	1.000
rs77870048 lBF = `25.4086` Chr`16` : `69,965,021`	0.000	0.000	1.000
rs17114036 lBF = `24.9599` Chr`1` : `56,962,821`	0.000	0.000	1.000
rs8035039 lBF = `24.7809` Chr`15` : `79,129,823`	0.000	0.000	1.000
rs72932557 lBF = `24.5835` Chr`2` : `203,846,817`	1.000	0.000	0.000
rs72934505 lBF = `24.4925` Chr`2` : `203,916,487`	1.000	0.000	0.000
rs2244608 lBF = `24.424` Chr`12` : `121,416,988`	1.000	0.000	0.000
rs4252117 lBF = `23.9062` Chr`6` : `161,143,376`	0.000	0.000	1.000
rs2351524 lBF = `23.7763` Chr`2` : `203,880,992`	1.000	0.000	0.000
rs6725887 lBF = `23.302` Chr`2` : `203,745,885`	1.000	0.000	0.000
rs3127573 lBF = `23.0824` Chr`6` : `160,681,393`	1.000	0.000	0.000
rs2929155 lBF = `22.93` Chr`15` : `79,058,013`	1.000	0.000	0.000
rs117446263 lBF = `22.5816` Chr`6` : `160,847,571`	1.000	0.000	0.000
rs7582720 lBF = `22.5385` Chr`2` : `203,753,072`	1.000	0.000	0.000
rs4252165 lBF = `22.4006` Chr`6` : `161,161,559`	0.000	0.000	1.000
rs35212307 lBF = `21.9102` Chr`2` : `203,765,756`	1.000	0.000	0.000
rs2074633 lBF = `21.593` Chr`7` : `19,035,920`	1.000	0.000	0.000
rs117019691 lBF = `21.5576` Chr`16` : `57,505,625`	1.000	0.000	0.000
rs4252125 lBF = `21.4942` Chr`6` : `161,152,240`	0.000	0.000	1.000
rs2128739 lBF = `21.4915` Chr`11` : `103,673,277`	0.000	0.000	1.000
rs115400054 lBF = `21.4703` Chr`2` : `203,676,105`	1.000	0.000	0.000
rs2019090 lBF = `21.1424` Chr`11` : `103,668,962`	0.000	0.000	1.000
rs974819 lBF = `21.0237` Chr`11` : `103,660,567`	0.000	0.000	1.000
rs17711010 lBF = `20.9663` Chr`17` : `47,485,962`	1.000	0.000	0.000
rs9457998 lBF = `20.9032` Chr`6` : `161,109,053`	1.000	0.000	0.000
rs73009507 lBF = `20.7347` Chr`19` : `10,961,024`	1.000	0.000	0.000
rs1412740 lBF = `20.463` Chr`6` : `12,817,590`	0.000	0.000	1.000
rs2378603 lBF = `20.0732` Chr`1` : `222,939,905`	0.000	0.000	1.000
rs15285 lBF = `20.0574` Chr`8` : `19,824,667`	0.000	0.000	1.000
rs783147 lBF = `19.4409` Chr`6` : `161,137,990`	0.000	0.000	1.000
rs483465 lBF = `19.2338` Chr`3` : `136,047,977`	1.000	0.000	0.000
rs6919346 lBF = `18.8431` Chr`6` : `160,960,359`	0.000	0.000	1.000
rs2083637 lBF = `18.8278` Chr`8` : `19,865,175`	0.000	0.000	1.000
rs12202017 lBF = `18.6278` Chr`6` : `134,173,151`	0.000	0.000	1.000
rs2219939 lBF = `18.5789` Chr`15` : `79,029,723`	0.000	0.000	1.000
rs1441756 lBF = `18.4586` Chr`8` : `19,868,386`	0.000	0.000	1.000
rs899997 lBF = `18.2795` Chr`15` : `79,019,578`	0.000	0.000	1.000
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rs71336078 lBF = `11.8752` Chr`3` : `136,489,602`	0.000	0.000	1.000
rs61789562 lBF = `10.4493` Chr`3` : `135,926,784`	0.000	0.000	1.000
rs223296 lBF = `5.60369` Chr`6` : `57,093,656`	1.000	0.000	0.000
rs4888383 lBF = `5.39799` Chr`16` : `75,386,349`	0.000	0.000	1.000
rs11860231 lBF = `5.10285` Chr`16` : `75,385,159`	0.000	0.000	1.000
rs4888372 lBF = `5.09511` Chr`16` : `75,313,485`	0.000	0.000	1.000
rs2071590 lBF = `76.0032` Chr`6` : `31,539,768`	0.000	0.000	1.000
rs2954031 lBF = `29.4155` Chr`8` : `126,491,733`	0.000	0.000	1.000
rs68168937 lBF = `14.6418` Chr`6` : `160,451,398`	1.000	0.000	0.000
rs1247563 lBF = `12.5596` Chr`6` : `161,205,949`	1.000	0.000	0.000
rs12902602 lBF = `11.8843` Chr`15` : `78,967,401`	0.000	0.000	1.000
rs61789642 lBF = `11.81` Chr`3` : `136,109,696`	0.000	0.000	1.000
rs4264001 lBF = `8.98164` Chr`1` : `222,946,338`	0.000	0.000	1.000
rs7253117 lBF = `8.58485` Chr`19` : `17,844,894`	1.000	0.000	0.000
rs2760743 lBF = `6.55443` Chr`17` : `2,017,079`	1.000	0.000	0.000
rs9355814 lBF = `5.58429` Chr`6` : `161,031,253`	0.000	0.000	1.000
rs3809272 lBF = `28.191` Chr`12` : `111,800,258`	0.000	0.000	1.000
rs116841826 lBF = `21.5796` Chr`7` : `150,543,427`	1.000	0.000	0.000
rs11057830 lBF = `17.2626` Chr`12` : `125,307,053`	1.000	0.000	0.000
rs34169052 lBF = `13.2244` Chr`3` : `136,468,000`	0.000	0.000	1.000
rs13209686 lBF = `13.1277` Chr`6` : `160,595,233`	1.000	0.000	0.000
rs3731249 lBF = `12.0614` Chr`9` : `21,970,916`	1.000	0.000	0.000
rs1021071 lBF = `11.7` Chr`15` : `78,968,179`	0.000	0.000	1.000
rs4886580 lBF = `11.1907` Chr`15` : `78,969,385`	0.000	0.000	1.000
rs7953249 lBF = `10.3556` Chr`12` : `121,403,724`	1.000	0.000	0.000
rs2384000 lBF = `9.34104` Chr`12` : `112,965,142`	0.000	0.000	1.000
rs62052821 lBF = `8.48117` Chr`16` : `69,598,657`	0.000	0.000	1.000
rs10790383 lBF = `6.82278` Chr`11` : `120,344,526`	1.000	0.000	0.000
rs1893261 lBF = `6.29427` Chr`11` : `120,198,093`	1.000	0.000	0.000
rs10945683 lBF = `5.38495` Chr`6` : `161,069,952`	0.000	0.000	1.000
rs8050059 lBF = `5.00877` Chr`16` : `75,388,731`	0.000	0.000	1.000
rs1564348 lBF = `20.2401` Chr`6` : `160,578,860`	1.000	0.000	0.000
rs326 lBF = `15.1404` Chr`8` : `19,819,439`	0.000	0.000	1.000
rs2251468 lBF = `12.8224` Chr`12` : `121,405,126`	0.000	0.000	1.000
rs191555775 lBF = `11.749` Chr`6` : `161,005,389`	0.000	0.000	1.000
rs4886579 lBF = `11.3251` Chr`15` : `78,969,256`	0.000	0.000	1.000
rs12202891 lBF = `9.76129` Chr`6` : `12,768,218`	1.000	0.000	0.000
rs2301756 lBF = `7.47329` Chr`12` : `112,890,776`	0.000	0.000	1.000
rs904324 lBF = `5.67751` Chr`1` : `222,790,465`	0.000	0.000	1.000
rs1994884 lBF = `5.45058` Chr`17` : `2,084,008`	1.000	0.000	0.000
rs2047009 lBF = `10.3414` Chr`10` : `44,539,913`	0.000	0.000	1.000
rs12875271 lBF = `6.70558` Chr`13` : `110,792,743`	0.000	0.000	1.000
rs10840293 lBF = `6.43536` Chr`11` : `9,751,196`	1.000	0.000	0.000
rs2857709 lBF = `104.056` Chr`6` : `31,532,814`	0.000	0.000	1.000
rs633185 lBF = `19.3362` Chr`11` : `100,593,538`	1.000	0.000	0.000
rs1154988 lBF = `14.8944` Chr`3` : `135,925,191`	1.000	0.000	0.000
rs72652478 lBF = `14.3802` Chr`9` : `22,102,043`	1.000	0.000	0.000
rs6495314 lBF = `11.5014` Chr`15` : `78,960,529`	0.000	0.000	1.000
rs1024065 lBF = `10.3744` Chr`1` : `222,761,601`	0.000	0.000	1.000
rs73013159 lBF = `8.54736` Chr`19` : `11,122,710`	0.000	0.000	1.000
rs11853441 lBF = `7.14776` Chr`15` : `91,400,208`	1.000	0.000	0.000
rs1679153 lBF = `6.7364` Chr`3` : `138,151,971`	1.000	0.000	0.000
rs73225862 lBF = `6.53187` Chr`8` : `22,050,584`	1.000	0.000	0.000
rs2250644 lBF = `6.52988` Chr`10` : `91,008,879`	1.000	0.000	0.000
rs1412444 lBF = `6.44557` Chr`10` : `91,002,927`	1.000	0.000	0.000
rs1177562 lBF = `5.39994` Chr`11` : `118,949,331`	1.000	0.000	0.000
rs1046080 lBF = `173.349` Chr`6` : `31,595,882`	0.000	0.000	1.000
rs2429722 lBF = `43.8626` Chr`6` : `31,064,305`	0.000	0.000	1.000
rs7904547 lBF = `10.7015` Chr`10` : `23,340,868`	0.000	0.000	1.000
rs2246833 lBF = `6.27332` Chr`10` : `91,005,854`	1.000	0.000	0.000
rs2001846 lBF = `27.8908` Chr`8` : `126,478,450`	0.000	0.000	1.000
rs268 lBF = `17.5199` Chr`8` : `19,813,529`	1.000	0.000	0.000
rs1529729 lBF = `12.5024` Chr`19` : `11,163,562`	1.000	0.000	0.000
rs511154 lBF = `11.7383` Chr`3` : `135,950,921`	1.000	0.000	0.000
rs2286195 lBF = `7.52235` Chr`7` : `139,728,584`	0.000	0.000	1.000
rs8109627 lBF = `7.31922` Chr`19` : `41,822,986`	0.000	0.000	1.000
rs2241718 lBF = `5.00712` Chr`19` : `41,829,606`	0.000	0.000	1.000
rs2272593 lBF = `170.088` Chr`6` : `31,601,344`	0.000	0.000	1.000
rs1129640 lBF = `63.7178` Chr`6` : `31,506,624`	0.000	0.000	1.000
rs4846382 lBF = `16.0138` Chr`1` : `222,721,288`	0.000	0.000	1.000
rs645040 lBF = `13.7796` Chr`3` : `135,926,622`	0.000	0.000	1.000
rs684773 lBF = `11.6661` Chr`3` : `135,956,305`	0.000	0.000	1.000
rs28664992 lBF = `8.06447` Chr`7` : `28,579,714`	1.000	0.000	0.000
rs701141 lBF = `7.99673` Chr`3` : `154,061,053`	0.000	0.000	1.000
rs1475865 lBF = `169.543` Chr`6` : `31,657,413`	0.000	0.000	1.000
rs75511781 lBF = `10.9224` Chr`7` : `131,323,710`	1.000	0.000	0.000
rs1996371 lBF = `10.4683` Chr`15` : `78,956,806`	0.000	0.000	1.000
rs58896911 lBF = `10.2837` Chr`7` : `28,639,955`	1.000	0.000	0.000
rs35304796 lBF = `6.87123` Chr`6` : `56,903,750`	1.000	0.000	0.000
rs2857597 lBF = `169.25` Chr`6` : `31,585,000`	0.000	0.000	1.000
rs3130617 lBF = `167.756` Chr`6` : `31,627,523`	0.000	0.000	1.000
rs152784 lBF = `14.4221` Chr`5` : `132,772,431`	0.000	0.000	1.000
rs10892562 lBF = `5.29003` Chr`11` : `120,221,618`	1.000	0.000	0.000
rs9845762 lBF = `8.28502` Chr`3` : `136,356,464`	0.000	0.000	1.000
rs325 lBF = `5.51521` Chr`8` : `19,819,328`	0.000	0.000	1.000
rs149615216 lBF = `5.16337` Chr`18` : `47,106,028`	0.000	0.000	1.000
rs2844670 lBF = `55.6631` Chr`6` : `31,005,726`	0.000	0.000	1.000
rs2001945 lBF = `27.7438` Chr`8` : `126,477,978`	1.000	0.000	0.000
rs72689147 lBF = `18.2481` Chr`4` : `156,639,888`	0.000	0.000	1.000
rs41272114 lBF = `9.8013` Chr`6` : `161,006,077`	0.000	0.000	1.000
rs355770 lBF = `6.89905` Chr`3` : `154,040,273`	0.000	0.000	1.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

Variant clusters with highest protective effect

(posterior probability > 0.05)

Cluster X0112

log Bayes Factor = 98.8923

contains 7 variants

Cluster X0002

log Bayes Factor = 522.044

contains 22 variants

Cluster X0034

log Bayes Factor = 665.104

contains 16 variants

Cluster X0228

log Bayes Factor = 196.521

contains 11 variants

Cluster X0199

log Bayes Factor = 350.038

contains 3 variants

Cluster X0186

log Bayes Factor = 35.9761

contains 2 variants

Cluster X0335

log Bayes Factor = 12.3689

contains 1 variants

Variant clusters with highest risk effect

(posterior probability > 0.05)

Cluster X0139

log Bayes Factor = 304.555

contains 10 variants

Cluster X0203

log Bayes Factor = 363.522

contains 11 variants

Cluster X0060

log Bayes Factor = 242.413

contains 5 variants

Cluster X0077

log Bayes Factor = 571.533

contains 17 variants

Cluster X0093

log Bayes Factor = 289.878

contains 10 variants

Cluster X0205

log Bayes Factor = 674.183

contains 18 variants

Cluster X0174

log Bayes Factor = 214.209

contains 8 variants

Cluster X0049

log Bayes Factor = 597.061

contains 18 variants

Cluster X0114

log Bayes Factor = 510.917

contains 25 variants

Cluster X0226

log Bayes Factor = 145.726

contains 8 variants

Cluster X0290

log Bayes Factor = 333.908

contains 13 variants

Cluster X0307

log Bayes Factor = 826.86

contains 2 variants

Cluster X0005

log Bayes Factor = 282.915

contains 11 variants

Cluster X0069

log Bayes Factor = 519.392

contains 20 variants

Cluster X0277

log Bayes Factor = 726.213

contains 23 variants

Cluster X0262

log Bayes Factor = 269.713

contains 9 variants

Cluster X0326

log Bayes Factor = 112.92

contains 5 variants

Cluster X0104

log Bayes Factor = 122.44

contains 5 variants

Cluster X0200

log Bayes Factor = 162.369

contains 2 variants

Cluster X0330

log Bayes Factor = 183.455

contains 2 variants

Cluster X0051

log Bayes Factor = 376.793

contains 14 variants

Cluster X0155

log Bayes Factor = 348.568

contains 12 variants

Cluster X0294

log Bayes Factor = 25.2869

contains 2 variants

Cluster X0150

log Bayes Factor = 861.091

contains 26 variants

Cluster X0028

log Bayes Factor = 120.445

contains 7 variants

Cluster X0261

log Bayes Factor = 420.614

contains 20 variants

Cluster X0284

log Bayes Factor = 192.532

contains 9 variants

Cluster X0142

log Bayes Factor = 295.63

contains 12 variants

Cluster X0134

log Bayes Factor = 151.731

contains 8 variants

Cluster X0178

log Bayes Factor = 225.6

contains 9 variants

Cluster X0177

log Bayes Factor = 254.872

contains 10 variants

Cluster X0204

log Bayes Factor = 169.796

contains 8 variants

Cluster X0297

log Bayes Factor = 63.8292

contains 4 variants

Cluster X0129

log Bayes Factor = 195.809

contains 7 variants

Cluster X0107

log Bayes Factor = 151.016

contains 1 variants

Cluster X0208

log Bayes Factor = 40.6733

contains 2 variants

Cluster X0064

log Bayes Factor = 166.06

contains 10 variants

Cluster X0143

log Bayes Factor = 179.808

contains 8 variants

Cluster X0250

log Bayes Factor = 43.399

contains 4 variants

Cluster X0271

log Bayes Factor = 256.743

contains 10 variants

Cluster X0238

log Bayes Factor = 97.9307

contains 4 variants

Cluster X0040

log Bayes Factor = 542.747

contains 16 variants

Cluster X0246

log Bayes Factor = 121.08

contains 5 variants

Cluster X0037

log Bayes Factor = 171.712

contains 6 variants

Cluster X0182

log Bayes Factor = 91.4459

contains 4 variants

Cluster X0190

log Bayes Factor = 15.3889

contains 2 variants

Cluster X0327

log Bayes Factor = 118.248

contains 3 variants

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.