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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs573687
log Bayes Factor = 96.1061
Chromosome 9   position 22,011,642  (GRCh37) Explore rs573687 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.000 1.000
H40.9 Glaucoma, unspecified
0.000 0.000 1.000
H40.1 Primary open-angle glaucoma
0.000 0.000 1.000
H40 Glaucoma
0.000 0.000 1.000
I20.0 Unstable angina
0.000 0.000 1.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.000 1.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.000 1.000
I22 Subsequent myocardial infarction
0.000 0.001 0.999
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.001 0.999
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.001 0.999
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.003 0.997
I73.9 Peripheral vascular disease, unspecified
0.000 0.003 0.997
I73 Other peripheral vascular diseases
0.000 0.004 0.996
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.007 0.993
I74 Arterial embolism and thrombosis
0.000 0.007 0.993
I21.4 Acute subendocardial myocardial infarction
0.000 0.009 0.991
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.011 0.989
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.013 0.987
I24 Other acute ischaemic heart diseases
0.000 0.014 0.986
Chapter IX Diseases of the circulatory system
0.000 0.028 0.972
H40.0 Glaucoma suspect
0.000 0.046 0.954
I20.8 Other forms of angina pectoris
0.000 0.051 0.949
I25.5 Ischaemic cardiomyopathy
0.000 0.053 0.947
I72 Other aneurysm
0.000 0.058 0.942
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.060 0.940
I24.8 Other forms of acute ischaemic heart disease
0.000 0.073 0.927
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.075 0.925
I65.2 Occlusion and stenosis of carotid artery
0.000 0.087 0.913
I60-I69 Cerebrovascular diseases
0.000 0.089 0.911
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.091 0.909
I25.4 Coronary artery aneurysm
0.000 0.098 0.902
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.103 0.897
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.125 0.875
I72.3 Aneurysm of iliac artery
0.000 0.134 0.866
C71 Malignant neoplasm of brain
0.863 0.137 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.142 0.858
H40.8 Other glaucoma
0.000 0.143 0.857
C71.9 Brain, unspecified
0.856 0.144 0.000
C71.1 Frontal lobe
0.854 0.146 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.178 0.822
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.186 0.814
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.195 0.804
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.202 0.798
C71.8 Overlapping lesion of brain
0.793 0.207 0.000
I70 Atherosclerosis
0.000 0.210 0.790
C71.3 Parietal lobe
0.786 0.214 0.000
I72.8 Aneurysm of other specified arteries
0.000 0.219 0.781
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.228 0.772
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.240 0.760
C71.0 Cerebrum, except lobes and ventricles
0.758 0.242 0.000
Z95.3 Presence of xenogenic heart valve
0.000 0.261 0.739
I74.8 Embolism and thrombosis of other arteries
0.000 0.262 0.738
C71.2 Temporal lobe
0.736 0.264 0.000
I25.3 Aneurysm of heart
0.000 0.264 0.736
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.265 0.735
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.271 0.729
I22.8 Subsequent myocardial infarction of other sites
0.000 0.276 0.724
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
H40.6 Glaucoma secondary to drugs
0.000 0.283 0.717
I72.9 Aneurysm of unspecified site
0.000 0.283 0.717
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.286 0.714
I72.2 Aneurysm of renal artery
0.000 0.286 0.714
I67 Other cerebrovascular diseases
0.000 0.293 0.707
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.297 0.703
I25.6 Silent myocardial ischaemia
0.000 0.301 0.699
I77 Other disorders of arteries and arterioles
0.000 0.301 0.699
Z95.2 Presence of prosthetic heart valve
0.000 0.306 0.694
I73.8 Other specified peripheral vascular diseases
0.000 0.314 0.685
I77.1 Stricture of artery
0.000 0.315 0.685
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.323 0.677
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.324 0.676
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.324 0.676
I72.1 Aneurysm of artery of upper extremity
0.000 0.324 0.676
I72.0 Aneurysm of carotid artery
0.000 0.331 0.669
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.339 0.661
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.340 0.660
I62 Other nontraumatic intracranial haemorrhage
0.000 0.342 0.658
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.347 0.653
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.348 0.652
I60 Subarachnoid haemorrhage
0.000 0.356 0.644
Z95.0 Presence of cardiac pacemaker
0.000 0.356 0.644
I23 Certain current complications following acute myocardial infarction
0.000 0.358 0.642
I70.1 Atherosclerosis of renal artery
0.000 0.358 0.642
H40.4 Glaucoma secondary to eye inflammation
0.000 0.359 0.641
I72.4 Aneurysm of artery of lower extremity
0.000 0.361 0.639
I00-I02 Acute rheumatic fever
0.000 0.368 0.632
H40.3 Glaucoma secondary to eye trauma
0.000 0.369 0.630
I20.1 Angina pectoris with documented spasm
0.000 0.372 0.628
C71.6 Cerebellum
0.619 0.381 0.000
C71.5 Cerebral ventricle
0.619 0.381 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.386 0.614
I67.9 Cerebrovascular disease, unspecified
0.000 0.394 0.606
C71.4 Occipital lobe
0.603 0.397 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.400 0.599
I24.1 Dressler's syndrome
0.000 0.405 0.595
H40.5 Glaucoma secondary to other eye disorders
0.000 0.408 0.592
I79.1 Aortitis in diseases classified elsewhere
0.000 0.411 0.589
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.411 0.589
I65.1 Occlusion and stenosis of basilar artery
0.000 0.412 0.588
I61 Intracerebral haemorrhage
0.000 0.415 0.585
I70.9 Generalised and unspecified atherosclerosis
0.000 0.421 0.579
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.434 0.566
C71.7 Brain stem
0.564 0.436 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.444 0.556
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.447 0.553
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.450 0.550
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.454 0.546
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.455 0.545
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.460 0.540
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.461 0.539
Z82.3 Family history of stroke
0.000 0.465 0.535
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.465 0.535
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.466 0.534
I70.8 Atherosclerosis of other arteries
0.000 0.466 0.534
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.488 0.512
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.488 0.512
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.488 0.512
I74.5 Embolism and thrombosis of iliac artery
0.000 0.488 0.511
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.493 0.507
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.493 0.507
I67.5 Moyamoya disease
0.000 0.493 0.507
I67.4 Hypertensive encephalopathy
0.000 0.493 0.507
I67.3 Progressive vascular leukoencephalopathy
0.000 0.493 0.507
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.496 0.504
I77.5 Necrosis of artery
0.000 0.499 0.501
I77.4 Coeliac artery compression syndrome
0.000 0.499 0.501
I77.3 Arterial fibromuscular dysplasia
0.000 0.499 0.501
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.506 0.494
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.506 0.494
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.512 0.488
I60.8 Other subarachnoid haemorrhage
0.000 0.515 0.485
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.516 0.484
I62.1 Nontraumatic extradural haemorrhage
0.000 0.519 0.481
I71 Aortic aneurysm and dissection
0.000 0.520 0.480
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.523 0.477
I77.0 Arteriovenous fistula, acquired
0.000 0.532 0.467
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.538 0.462
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.539 0.461
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.539 0.461
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.539 0.461
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.539 0.461
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.539 0.461
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.539 0.461
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.539 0.461
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.540 0.460
I67.2 Cerebral atherosclerosis
0.000 0.543 0.457
I70.0 Atherosclerosis of aorta
0.000 0.544 0.456
I02 Rheumatic chorea
0.000 0.547 0.453
I01 Rheumatic fever with heart involvement
0.000 0.547 0.453
I78 Diseases of capillaries
0.000 0.550 0.450
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.551 0.449
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.559 0.440
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.559 0.440
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.559 0.440
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.561 0.439
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.562 0.438
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.563 0.436
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.571 0.429
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.572 0.428
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.572 0.428
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.577 0.423
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.577 0.423
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.580 0.420
H40-H42 Glaucoma
0.000 0.582 0.418
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.584 0.415
H40.2 Primary angle-closure glaucoma
0.000 0.591 0.409
I68.0 Cerebral amyloid angiopathy
0.000 0.598 0.402
I99 Other and unspecified disorders of circulatory system
0.000 0.599 0.401
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.605 0.395
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.609 0.391
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.609 0.391
I05-I09 Chronic rheumatic heart diseases
0.000 0.610 0.390
I00 Rheumatic fever without mention of heart involvement
0.000 0.612 0.387
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.613 0.387
I23.8 Other current complications following acute myocardial infarction
0.000 0.614 0.386
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.615 0.385
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.617 0.383
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.619 0.381
I77.2 Rupture of artery
0.000 0.629 0.370
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.630 0.370
Z82.1 Family history of blindness and visual loss
0.000 0.636 0.364
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.361 0.639 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.642 0.358
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.650 0.350
Z82.2 Family history of deafness and hearing loss
0.000 0.653 0.347
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.656 0.344
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.656 0.344
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.656 0.344
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.663 0.337
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.665 0.335
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.673 0.327
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.675 0.325
I01.8 Other acute rheumatic heart disease
0.000 0.675 0.325
I01.2 Acute rheumatic myocarditis
0.000 0.675 0.325
I01.1 Acute rheumatic endocarditis
0.000 0.675 0.325
I01.0 Acute rheumatic pericarditis
0.000 0.675 0.325
I02.9 Rheumatic chorea without heart involvement
0.000 0.675 0.325
I02.0 Rheumatic chorea with heart involvement
0.000 0.675 0.325
I78.9 Disease of capillaries, unspecified
0.000 0.677 0.322
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.678 0.322
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.679 0.321
I67.1 Cerebral aneurysm, nonruptured
0.000 0.681 0.319
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.684 0.315
I78.8 Other diseases of capillaries
0.000 0.686 0.314
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.686 0.314
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.687 0.312
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.689 0.311
I71.0 Dissection of aorta [any part]
0.000 0.689 0.311
I09 Other rheumatic heart diseases
0.000 0.694 0.306
I61.8 Other intracerebral haemorrhage
0.000 0.700 0.300
H42 Glaucoma in diseases classified elsewhere
0.000 0.700 0.300
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.700 0.299
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.708 0.292
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.713 0.287
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.715 0.285
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.716 0.283
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.716 0.283
I98.0 Cardiovascular syphilis
0.000 0.716 0.283
I06 Rheumatic aortic valve diseases
0.000 0.726 0.274
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.270 0.730 0.000
Z95.4 Presence of other heart-valve replacement
0.000 0.732 0.267
I77.8 Other specified disorders of arteries and arterioles
0.001 0.737 0.262
I07 Rheumatic tricuspid valve diseases
0.000 0.746 0.254
I97.1 Other functional disturbances following cardiac surgery
0.000 0.749 0.251
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.749 0.251
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.002 0.749 0.249
C69 Malignant neoplasm of eye and adnexa
0.249 0.751 0.000
E11.9 Without complications
0.000 0.751 0.249
I09.9 Rheumatic heart disease, unspecified
0.000 0.754 0.245
I69 Sequelae of cerebrovascular disease
0.000 0.765 0.235
E11 Non-insulin-dependent diabetes mellitus
0.000 0.765 0.235
I97.0 Postcardiotomy syndrome
0.000 0.769 0.231
I05 Rheumatic mitral valve diseases
0.000 0.769 0.231
E11.1 With ketoacidosis
0.000 0.775 0.225
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.775 0.224
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.778 0.222
I09.8 Other specified rheumatic heart diseases
0.000 0.781 0.219
I09.2 Chronic rheumatic pericarditis
0.000 0.781 0.219
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.781 0.219
I09.0 Rheumatic myocarditis
0.000 0.781 0.219
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.784 0.216
C70 Malignant neoplasm of meninges
0.215 0.784 0.000
H42.8 Glaucoma in other diseases classified elsewhere
0.000 0.785 0.215
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases
0.000 0.785 0.215
I28 Other diseases of pulmonary vessels
0.000 0.788 0.212
E11.5 With peripheral circulatory complications
0.000 0.791 0.209
E11.4 With neurological complications
0.000 0.792 0.208
C72.0 Spinal cord
0.205 0.795 0.000
I06.1 Rheumatic aortic insufficiency
0.000 0.797 0.203
C69.2 Retina
0.197 0.803 0.000
I06.8 Other rheumatic aortic valve diseases
0.000 0.803 0.197
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.803 0.197
I06.0 Rheumatic aortic stenosis
0.000 0.806 0.194
C72.9 Central nervous system, unspecified
0.194 0.806 0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.194 0.806 0.000
C72.5 Other and unspecified cranial nerves
0.194 0.806 0.000
C72.4 Acoustic nerve
0.194 0.806 0.000
C72.3 Optic nerve
0.194 0.806 0.000
C72.2 Olfactory nerve
0.194 0.806 0.000
C72.1 Cauda equina
0.194 0.806 0.000
C69.9 Eye, unspecified
0.192 0.808 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.808 0.192
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.813 0.187
I77.6 Arteritis, unspecified
0.000 0.815 0.185
I63 Cerebral infarction
0.000 0.816 0.184
C69.6 Orbit
0.184 0.816 0.000
I05.1 Rheumatic mitral insufficiency
0.000 0.816 0.184
I07.9 Tricuspid valve disease, unspecified
0.000 0.818 0.182
I07.8 Other tricuspid valve diseases
0.000 0.818 0.182
I07.2 Tricuspid stenosis with insufficiency
0.000 0.818 0.182
I07.0 Tricuspid stenosis
0.000 0.818 0.182
E11.8 With unspecified complications
0.000 0.820 0.180
C69.8 Overlapping lesion of eye and adnexa
0.179 0.821 0.000
C69.5 Lachrymal gland and duct
0.179 0.821 0.000
C69.4 Ciliary body
0.179 0.821 0.000
C69.1 Cornea
0.179 0.821 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.821 0.178
E78.0 Pure hypercholesterolaemia
0.000 0.823 0.177
I73.0 Raynaud's syndrome
0.000 0.825 0.175
I69.3 Sequelae of cerebral infarction
0.000 0.826 0.174
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.826 0.174
I28.8 Other specified diseases of pulmonary vessels
0.000 0.827 0.173
C69.0 Conjunctiva
0.170 0.829 0.000
E11.0 With coma
0.000 0.832 0.168
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.001 0.834 0.165
I05.8 Other mitral valve diseases
0.000 0.834 0.165
I05.2 Mitral stenosis with insufficiency
0.000 0.836 0.164
E11.7 With multiple complications
0.000 0.837 0.163
E11.6 With other specified complications
0.000 0.844 0.156
I07.1 Tricuspid insufficiency
0.000 0.844 0.156
C70.9 Meninges, unspecified
0.155 0.845 0.000
C70.1 Spinal meninges
0.155 0.845 0.000
E10-E14 Diabetes mellitus
0.000 0.847 0.153
I28.1 Aneurysm of pulmonary artery
0.000 0.847 0.152
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.847 0.152
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.850 0.150
I10-I15 Hypertensive diseases
0.000 0.860 0.140
I05.0 Mitral stenosis
0.000 0.860 0.140
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.860 0.140
E14 Unspecified diabetes mellitus
0.000 0.863 0.137
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.866 0.133
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.868 0.132
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.868 0.132
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.870 0.130
E10 Insulin-dependent diabetes mellitus
0.000 0.872 0.128
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.873 0.127
C44.3 Skin of other and unspecified parts of face
0.123 0.877 0.000
C44 Other malignant neoplasms of skin
0.123 0.877 0.000
E11.2 With renal complications
0.000 0.879 0.121
C69.3 Choroid
0.120 0.880 0.000
E14.3 With ophthalmic complications
0.000 0.880 0.120
I05.9 Mitral valve disease, unspecified
0.000 0.881 0.119
C44.5 Skin of trunk
0.119 0.881 0.000
E14.6 With other specified complications
0.000 0.884 0.116
E14.4 With neurological complications
0.000 0.885 0.115
C70.0 Cerebral meninges
0.111 0.888 0.001
E10.3 With ophthalmic complications
0.000 0.889 0.111
E14.1 With ketoacidosis
0.000 0.889 0.110
E12 Malnutrition-related diabetes mellitus
0.000 0.890 0.110
C44.0 Skin of lip
0.109 0.891 0.000
C16 Malignant neoplasm of stomach
0.107 0.893 0.000
C15 Malignant neoplasm of oesophagus
0.107 0.893 0.000
C15.9 Oesophagus, unspecified
0.106 0.894 0.000
C16.0 Cardia
0.106 0.894 0.000
E14.2 Withrenal complications
0.000 0.895 0.105
C43-C44 Melanoma and other malignant neoplasms of skin
0.105 0.895 0.000
C15-C26 Malignant neoplasms of digestive organs
0.105 0.895 0.000
C15.5 Lower third of oesophagus
0.104 0.896 0.000
I26 Pulmonary embolism
0.000 0.896 0.103
E10.5 With peripheral circulatory complications
0.000 0.898 0.102
E14.8 With unspecified complications
0.000 0.898 0.102
Chapter II Neoplasms
0.101 0.899 0.000
C44.4 Skin of scalp and neck
0.101 0.899 0.000
I13 Hypertensive heart and renal disease
0.000 0.899 0.101
C44.1 Skin of eyelid, including canthus
0.101 0.899 0.000
C44.2 Skin of ear and external auricular canal
0.101 0.899 0.000
E10.4 With neurological complications
0.000 0.900 0.100
E14.7 With multiple complications
0.000 0.901 0.099
E14.0 With coma
0.000 0.901 0.099
C16.9 Stomach, unspecified
0.098 0.902 0.000
I08 Multiple valve diseases
0.000 0.902 0.098
I67.8 Other specified cerebrovascular diseases
0.000 0.902 0.098
E10.9 Without complications
0.000 0.902 0.098
C17 Malignant neoplasm of small intestine
0.096 0.904 0.000
I11 Hypertensive heart disease
0.000 0.906 0.094
C44.6 Skin of upper limb, including shoulder
0.094 0.906 0.000
E10.8 With unspecified complications
0.000 0.907 0.093
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.092 0.908 0.000
E10.0 With coma
0.000 0.909 0.091
D00-D09 In situ neoplasms
0.091 0.909 0.000
C16.5 Lesser curvature of stomach, unspecified
0.089 0.911 0.000
E10.6 With other specified complications
0.000 0.911 0.089
C44.8 Overlapping lesion of skin
0.088 0.911 0.000
D04 Carcinoma in situ of skin
0.088 0.912 0.000
D04.3 Skin of other and unspecified parts of face
0.088 0.912 0.000
E10.1 With ketoacidosis
0.000 0.914 0.086
C17.0 Duodenum
0.086 0.914 0.000
C16.6 Greater curvature of stomach, unspecified
0.085 0.915 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.085 0.915 0.000
E10.7 With multiple complications
0.000 0.916 0.084
C16.8 Overlapping lesion of stomach
0.083 0.917 0.000
E14.5 With peripheral circulatory complications
0.000 0.917 0.083
D04.2 Skin of ear and external auricular canal
0.082 0.918 0.000
C15.0 Cervical part of oesophagus
0.081 0.918 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.081 0.919 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.081 0.919 0.000
I08.8 Other multiple valve diseases
0.000 0.920 0.080
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.080 0.920 0.000
D05 Carcinoma in situ of breast
0.080 0.920 0.000
E10.2 With renal complications
0.000 0.920 0.080
C15.3 Upper third of oesophagus
0.079 0.920 0.000
E12.9 Without complications
0.000 0.921 0.079
E12.8 With unspecified complications
0.000 0.921 0.079
E12.7 With multiple complications
0.000 0.921 0.079
E12.6 With other specified complications
0.000 0.921 0.079
E12.5 With peripheral circulatory complications
0.000 0.921 0.079
E12.4 With neurological complications
0.000 0.921 0.079
E12.3 With ophthalmic complications
0.000 0.921 0.079
E12.2 With renal complications
0.000 0.921 0.079
E12.1 With ketoacidosis
0.000 0.921 0.079
E12.0 With coma
0.000 0.921 0.079
I08.9 Multiple valve disease, unspecified
0.000 0.922 0.078
C16.1 Fundus of stomach
0.078 0.922 0.000
E13 Other specified diabetes mellitus
0.000 0.923 0.077
C15.8 Overlapping lesion of oesophagus
0.077 0.923 0.000
C15.2 Abdominal part of oesophagus
0.077 0.923 0.000
C15.1 Thoracic part of oesophagus
0.077 0.923 0.000
D02.0 Larynx
0.077 0.923 0.000
C17.9 Small intestine, unspecified
0.077 0.923 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.001 0.923 0.076
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.923 0.077
C16.2 Body of stomach
0.076 0.924 0.000
C21 Malignant neoplasm of anus and anal canal
0.076 0.924 0.000
I15 Secondary hypertension
0.000 0.925 0.075
C23 Malignant neoplasm of gallbladder
0.075 0.925 0.000
C17.2 Ileum
0.074 0.926 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.074 0.926 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.074 0.926 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.074 0.926 0.000
C20 Malignant neoplasm of rectum
0.074 0.926 0.000
D04.0 Skin of lip
0.073 0.926 0.000
C11 Malignant neoplasm of nasopharynx
0.073 0.927 0.000
C07 Malignant neoplasm of parotid gland
0.073 0.927 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.927 0.072
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.927 0.072
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.927 0.072
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.927 0.072
D05.7 Other carcinoma in situ of breast
0.072 0.928 0.000
C10 Malignant neoplasm of oropharynx
0.072 0.928 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.928 0.072
C03 Malignant neoplasm of gum
0.072 0.928 0.000
C02.9 Tongue, unspecified
0.072 0.928 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.072 0.928 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.071 0.929 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.071 0.929 0.000
C16.4 Pylorus
0.071 0.929 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.930 0.070
D04.9 Skin, unspecified
0.070 0.930 0.000
D02.2 Bronchus and lung
0.069 0.931 0.000
C30.0 Nasal cavity
0.069 0.931 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.069 0.931 0.000
C13 Malignant neoplasm of hypopharynx
0.069 0.931 0.000
C17.8 Overlapping lesion of small intestine
0.069 0.931 0.000
C17.3 Meckel's diverticulum
0.069 0.931 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.069 0.931 0.000
C00 Malignant neoplasm of lip
0.068 0.932 0.000
E11.3 With ophthalmic complications
0.000 0.932 0.068
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.933 0.066
C40-C41 Malignant neoplasms of bone and articular cartilage
0.066 0.934 0.000
C01 Malignant neoplasm of base of tongue
0.065 0.935 0.000
C48.0 Retroperitoneum
0.064 0.936 0.000
D04.8 Skin of other sites
0.063 0.936 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.937 0.063
C17.1 Jejunum
0.063 0.937 0.000
C02.2 Ventral surface of tongue
0.063 0.937 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.062 0.938 0.000
D04.4 Skin of scalp and neck
0.062 0.938 0.000
C04 Malignant neoplasm of floor of mouth
0.062 0.938 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.062 0.938 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.062 0.938 0.000
C31 Malignant neoplasm of accessory sinuses
0.061 0.939 0.000
D02.4 Respiratory system, unspecified
0.061 0.939 0.000
D02.3 Other parts of respiratory system
0.061 0.939 0.000
D02.1 Trachea
0.061 0.939 0.000
D09 Carcinoma in situ of other and unspecified sites
0.061 0.939 0.000
C14.0 Pharynx, unspecified
0.061 0.939 0.000
C37 Malignant neoplasm of thymus
0.060 0.940 0.000
D04.1 Skin of eyelid, including canthus
0.060 0.940 0.000
C02.1 Border of tongue
0.060 0.940 0.000
C05 Malignant neoplasm of palate
0.060 0.940 0.000
C11.9 Nasopharynx, unspecified
0.060 0.940 0.000
C02.8 Overlapping lesion of tongue
0.058 0.941 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.058 0.941 0.000
C02.0 Dorsal surface of tongue
0.058 0.941 0.000
C46 Kaposi's sarcoma
0.058 0.942 0.000
C10.9 Oropharynx, unspecified
0.058 0.942 0.000
C21.0 Anus, unspecified
0.058 0.942 0.000
C12 Malignant neoplasm of pyriform sinus
0.058 0.942 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.058 0.942 0.000
C33 Malignant neoplasm of trachea
0.058 0.942 0.000
C03.9 Gum, unspecified
0.057 0.942 0.000
E13.3 With ophthalmic complications
0.000 0.943 0.057
C06 Malignant neoplasm of other and unspecified parts of mouth
0.057 0.943 0.000
C02.4 Lingual tonsil
0.057 0.943 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.056 0.943 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.944 0.056
C32 Malignant neoplasm of larynx
0.056 0.944 0.000
C08.9 Major salivary gland, unspecified
0.056 0.944 0.000
E13.8 With unspecified complications
0.000 0.944 0.055
E13.7 With multiple complications
0.000 0.944 0.055
E13.6 With other specified complications
0.000 0.944 0.055
E13.5 With peripheral circulatory complications
0.000 0.944 0.055
E13.4 With neurological complications
0.000 0.944 0.055
E13.2 With renal complications
0.000 0.944 0.055
E13.1 With ketoacidosis
0.000 0.944 0.055
E13.0 With coma
0.000 0.944 0.055
D01.2 Rectum
0.055 0.945 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.054 0.945 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.055 0.945 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.945 0.055
C21.2 Cloacogenic zone
0.054 0.945 0.000
I15.8 Other secondary hypertension
0.000 0.946 0.054
I15.2 Hypertension secondary to endocrine disorders
0.000 0.946 0.054
C13.0 Postcricoid region
0.054 0.946 0.000
C00.0 External upper lip
0.054 0.946 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.054 0.946 0.000
C16.3 Pyloric antrum
0.053 0.946 0.000
I63.8 Other cerebral infarction
0.000 0.946 0.053
K76.8 Other specified diseases of liver
0.054 0.946 0.000
C30.1 Middle ear
0.053 0.947 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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