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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1994884
log Bayes Factor = 5.45058
Chromosome 17   position 2,084,008  (GRCh37) Explore rs1994884 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.997 0.003 0.000
M17.9 Gonarthrosis, unspecified
0.913 0.087 0.000
I25.2 Old myocardial infarction
0.808 0.192 0.000
I25.3 Aneurysm of heart
0.806 0.194 0.000
I25.4 Coronary artery aneurysm
0.794 0.206 0.000
I25.5 Ischaemic cardiomyopathy
0.788 0.212 0.000
M17 Gonarthrosis [arthrosis of knee]
0.747 0.253 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
M17.0 Primary gonarthrosis, bilateral
0.709 0.291 0.000
I20-I25 Ischaemic heart diseases
0.695 0.305 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.675 0.325 0.000
I22 Subsequent myocardial infarction
0.659 0.341 0.000
M17.5 Other secondary gonarthrosis
0.643 0.357 0.000
I24 Other acute ischaemic heart diseases
0.602 0.398 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.597 0.403 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.586 0.414 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.547 0.453 0.000
M17.3 Other posttraumatic gonarthrosis
0.542 0.458 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.537 0.463 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.536 0.464 0.000
I23 Certain current complications following acute myocardial infarction
0.536 0.464 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.528 0.471 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.485 0.515 0.000
I24.1 Dressler's syndrome
0.450 0.550 0.000
I23.8 Other current complications following acute myocardial infarction
0.421 0.579 0.000
I21 Acute myocardial infarction
0.391 0.609 0.000
I21.9 Acute myocardial infarction, unspecified
0.388 0.612 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.384 0.616 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.384 0.616 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.384 0.616 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.384 0.616 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.384 0.616 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.384 0.616 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.384 0.616 0.000
M17.1 Other primary gonarthrosis
0.364 0.636 0.000
I22.8 Subsequent myocardial infarction of other sites
0.347 0.652 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.326 0.674 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.281 0.719 0.000
I24.8 Other forms of acute ischaemic heart disease
0.265 0.735 0.000
I21.4 Acute subendocardial myocardial infarction
0.215 0.785 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.201 0.799 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.199 0.801 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.167 0.833 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.161 0.839 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.156 0.844 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.146 0.854 0.000
M23 Internal derangement of knee
0.143 0.857 0.000
M23.3 Other meniscus derangements
0.136 0.864 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.128 0.872 0.000
I20 Angina pectoris
0.127 0.873 0.000
D86.9 Sarcoidosis, unspecified
0.127 0.873 0.000
D86.8 Sarcoidosis of other and combined sites
0.125 0.875 0.000
D86 Sarcoidosis
0.124 0.876 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.121 0.879 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.121 0.879 0.000
C71 Malignant neoplasm of brain
0.000 0.881 0.119
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.117 0.883 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.116 0.884 0.000
M23.4 Loose body in knee
0.115 0.885 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.113 0.887 0.000
C71.9 Brain, unspecified
0.000 0.887 0.113
M23.30 Other meniscus derangements (Multiple sites)
0.113 0.887 0.000
M23.9 Internal derangement of knee, unspecified
0.112 0.888 0.000
C71.3 Parietal lobe
0.000 0.889 0.111
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.108 0.892 0.000
C71.8 Overlapping lesion of brain
0.000 0.892 0.108
C71.1 Frontal lobe
0.000 0.893 0.107
M23.43 Loose body in knee-Med lig/oth men
0.106 0.894 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.106 0.894 0.000
D86.0 Sarcoidosis of lung
0.105 0.895 0.000
C71.0 Cerebrum, except lobes and ventricles
0.000 0.897 0.103
C71.2 Temporal lobe
0.000 0.901 0.099
M23.37 Other meniscus derangements-Capsular lig
0.098 0.902 0.000
M23.1 Discoid meniscus (congenital)
0.098 0.902 0.000
D86.3 Sarcoidosis of skin
0.095 0.905 0.000
M23.8 Other internal derangements of knee
0.095 0.905 0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.092 0.908 0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)
0.092 0.908 0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)
0.092 0.908 0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp
0.092 0.908 0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn
0.092 0.908 0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.092 0.908 0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.092 0.908 0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.092 0.908 0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)
0.092 0.908 0.000
I20.1 Angina pectoris with documented spasm
0.090 0.910 0.000
M23.0 Cystic meniscus
0.089 0.911 0.000
C71.4 Occipital lobe
0.000 0.911 0.089
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.089 0.911 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.087 0.913 0.000
C71.7 Brain stem
0.000 0.915 0.085
C71.6 Cerebellum
0.000 0.915 0.085
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.083 0.917 0.000
M23.5 Chronic instability of knee
0.083 0.917 0.000
M23.40 Loose body in knee-Mult sites
0.083 0.917 0.000
M23.47 Loose body in knee-Capsular lig
0.082 0.917 0.000
M23.45 Loose body in knee-Pst hrn lat men
0.082 0.917 0.000
M23.44 Loose body in knee-Lat lig/ant men
0.082 0.917 0.000
M23.42 Loose body in knee-Pst lig/hrn men
0.082 0.917 0.000
D86.1 Sarcoidosis of lymph nodes
0.082 0.918 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.082 0.918 0.000
M23.41 Loose body in knee-Ant lig/hrn men
0.082 0.918 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.082 0.918 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.082 0.918 0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)
0.081 0.919 0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)
0.081 0.919 0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)
0.081 0.919 0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.081 0.919 0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.081 0.919 0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)
0.081 0.919 0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)
0.079 0.920 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.079 0.921 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.079 0.921 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.077 0.923 0.000
C71.5 Cerebral ventricle
0.000 0.924 0.076
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.076 0.924 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.075 0.925 0.000
M23.46 Loose body in knee-O/unsp lat men
0.073 0.927 0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)
0.070 0.930 0.000
M23.17 Discoid meniscus (congenital)-Capsular lig
0.070 0.930 0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)
0.070 0.930 0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.070 0.930 0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)
0.070 0.930 0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.070 0.930 0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.070 0.930 0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)
0.070 0.930 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.068 0.932 0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.067 0.933 0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)
0.067 0.933 0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)
0.065 0.934 0.000
M23.07 Cystic meniscus-Capsular lig
0.064 0.936 0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)
0.064 0.936 0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.064 0.936 0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.064 0.936 0.000
M23.00 Cystic meniscus (Multiple sites)
0.064 0.936 0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)
0.063 0.937 0.000
M23.49 Loose body in knee-Unspec lig/men
0.063 0.937 0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.062 0.938 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.060 0.940 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.060 0.940 0.000
M23.57 Chronic instability of knee (Capsular ligament)
0.059 0.940 0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)
0.059 0.940 0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)
0.059 0.940 0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.059 0.940 0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.059 0.940 0.000
M23.50 Chronic instability of knee (Multiple sites)
0.059 0.940 0.000
I20.8 Other forms of angina pectoris
0.059 0.941 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.057 0.943 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.056 0.944 0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)
0.055 0.945 0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.052 0.948 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.052 0.948 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.951 0.049
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.047 0.953 0.000
I20.9 Angina pectoris, unspecified
0.047 0.953 0.000
I71 Aortic aneurysm and dissection
0.036 0.964 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.000 0.965 0.035
C69 Malignant neoplasm of eye and adnexa
0.000 0.965 0.035
I20.0 Unstable angina
0.035 0.965 0.000
C70 Malignant neoplasm of meninges
0.000 0.965 0.035
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.035 0.965 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.033 0.967 0.000
D80-D89 Certain disorders involving the immune mechanism
0.033 0.967 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.032 0.968 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.032 0.968 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.031 0.969 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.031 0.969 0.000
M15-M19 Arthrosis
0.030 0.970 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.030 0.970 0.000
I71.0 Dissection of aorta [any part]
0.029 0.971 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.029 0.971 0.000
C69.3 Choroid
0.000 0.973 0.027
D84 Other immunodeficiencies
0.026 0.974 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.026 0.974 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.026 0.974 0.000
C72.0 Spinal cord
0.000 0.974 0.025
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.026 0.974 0.000
C72.9 Central nervous system, unspecified
0.000 0.974 0.025
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.000 0.974 0.025
C72.5 Other and unspecified cranial nerves
0.000 0.974 0.025
C72.4 Acoustic nerve
0.000 0.974 0.025
C72.3 Optic nerve
0.000 0.974 0.025
C72.2 Olfactory nerve
0.000 0.974 0.025
C72.1 Cauda equina
0.000 0.974 0.025
C69.8 Overlapping lesion of eye and adnexa
0.000 0.975 0.025
C69.6 Orbit
0.000 0.975 0.025
C69.5 Lachrymal gland and duct
0.000 0.975 0.025
C69.4 Ciliary body
0.000 0.975 0.025
C69.2 Retina
0.000 0.975 0.025
C69.1 Cornea
0.000 0.975 0.025
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.025 0.975 0.000
C70.9 Meninges, unspecified
0.000 0.975 0.025
C70.1 Spinal meninges
0.000 0.975 0.025
C69.0 Conjunctiva
0.000 0.975 0.025
C70.0 Cerebral meninges
0.000 0.975 0.024
D82 Immunodeficiency associated with other major defects
0.024 0.976 0.000
D81 Combined immunodeficiencies
0.024 0.976 0.000
D84.1 Defects in the complement system
0.023 0.977 0.000
C69.9 Eye, unspecified
0.000 0.977 0.023
M15 Polyarthrosis
0.022 0.978 0.000
D83 Common variable immunodeficiency
0.022 0.978 0.000
D80 Immunodeficiency with predominantly antibody defects
0.021 0.979 0.000
I72 Other aneurysm
0.021 0.979 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.020 0.980 0.000
Chapter IX Diseases of the circulatory system
0.019 0.981 0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.019 0.981 0.000
I72.8 Aneurysm of other specified arteries
0.019 0.981 0.000
I72.3 Aneurysm of iliac artery
0.019 0.981 0.000
D82.1 Di George's syndrome
0.018 0.982 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.018 0.982 0.000
D84.9 Immunodeficiency, unspecified
0.018 0.982 0.000
D84.8 Other specified immunodeficiencies
0.018 0.982 0.000
D82.9 Immunodeficiency associated with major defect, unspecified
0.018 0.982 0.000
D82.8 Immunodeficiency associated with other specified major defects
0.018 0.982 0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.018 0.982 0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.018 0.982 0.000
D82.2 Immunodeficiency with short-limbed stature
0.018 0.982 0.000
D82.0 Wiskott-Aldrich syndrome
0.018 0.982 0.000
R19.4 Change in bowel habit
0.018 0.982 0.000
D81.9 Combined immunodeficiency, unspecified
0.017 0.983 0.000
D81.8 Other combined immunodeficiencies
0.017 0.983 0.000
D81.7 Major histocompatibility complex class II deficiency
0.017 0.983 0.000
D81.6 Major histocompatibility complex class I deficiency
0.017 0.983 0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.017 0.983 0.000
D81.4 Nezelof's syndrome
0.017 0.983 0.000
D81.3 Adenosine deaminase [ADA] deficiency
0.017 0.983 0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.017 0.983 0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.017 0.983 0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.017 0.983 0.000
I72.0 Aneurysm of carotid artery
0.017 0.983 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.017 0.983 0.000
I00-I02 Acute rheumatic fever
0.016 0.983 0.000
I72.9 Aneurysm of unspecified site
0.016 0.984 0.000
M15.1 Heberden's nodes (with arthropathy)
0.016 0.984 0.000
M15.9 Polyarthrosis, unspecified
0.016 0.984 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.016 0.984 0.000
M15.0 Primary generalised (osteo)arthrosis
0.016 0.984 0.000
I72.2 Aneurysm of renal artery
0.016 0.984 0.000
D83.8 Other common variable immunodeficiencies
0.016 0.984 0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.016 0.984 0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.016 0.984 0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.016 0.984 0.000
M15.4 Erosive (osteo)arthrosis
0.016 0.984 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.016 0.984 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.015 0.984 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.015 0.984 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.015 0.984 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.015 0.984 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.015 0.984 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.015 0.984 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.015 0.985 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.015 0.985 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.015 0.985 0.000
I72.1 Aneurysm of artery of upper extremity
0.015 0.985 0.000
I00 Rheumatic fever without mention of heart involvement
0.014 0.985 0.000
M15.3 Secondary multiple arthrosis
0.014 0.986 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.014 0.986 0.000
D83.9 Common variable immunodeficiency, unspecified
0.014 0.986 0.000
I07.1 Tricuspid insufficiency
0.013 0.987 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.013 0.987 0.000
M15.8 Other polyarthrosis
0.013 0.987 0.000
S82.50 Fracture of medial malleolus (closed)
0.013 0.987 0.000
I07 Rheumatic tricuspid valve diseases
0.013 0.987 0.000
I72.4 Aneurysm of artery of lower extremity
0.013 0.987 0.000
I05-I09 Chronic rheumatic heart diseases
0.012 0.987 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.013 0.987 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.012 0.987 0.000
I78 Diseases of capillaries
0.012 0.988 0.000
M15.99 Polyosteoarthritis, unspecified
0.012 0.988 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.012 0.988 0.000
I02 Rheumatic chorea
0.012 0.988 0.000
I01 Rheumatic fever with heart involvement
0.012 0.988 0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites
0.011 0.988 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.011 0.988 0.000
I70 Atherosclerosis
0.011 0.989 0.000
M80-M85 Disorders of bone density and structure
0.011 0.989 0.000
M20-M25 Other joint disorders
0.011 0.989 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.011 0.989 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.011 0.989 0.000
M65 Synovitis and tenosynovitis
0.011 0.989 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.011 0.989 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.011 0.989 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.011 0.989 0.000
M81 Osteoporosis without pathological fracture
0.011 0.989 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.010 0.989 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.010 0.990 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.010 0.990 0.000
M85 Other disorders of bone density and structure
0.010 0.990 0.000
I78.8 Other diseases of capillaries
0.010 0.990 0.000
M65-M68 Disorders of synovium and tendon
0.010 0.990 0.000
M80 Osteoporosis with pathological fracture
0.010 0.990 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.010 0.990 0.000
D89.3 Immune reconstitution syndrome
0.010 0.990 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.009 0.990 0.000
M81.4 Drug-induced osteoporosis
0.010 0.990 0.000
M79.67 Pain in limb (Ankle and foot)
0.010 0.990 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.009 0.990 0.000
I07.9 Tricuspid valve disease, unspecified
0.009 0.991 0.000
I07.8 Other tricuspid valve diseases
0.009 0.991 0.000
I07.2 Tricuspid stenosis with insufficiency
0.009 0.991 0.000
I07.0 Tricuspid stenosis
0.009 0.991 0.000
I09 Other rheumatic heart diseases
0.009 0.991 0.000
M82 Osteoporosis in diseases classified elsewhere
0.009 0.991 0.000
I70.8 Atherosclerosis of other arteries
0.009 0.991 0.000
M85.6 Other cyst of bone
0.009 0.991 0.000
I79.1 Aortitis in diseases classified elsewhere
0.009 0.991 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.009 0.991 0.000
I06 Rheumatic aortic valve diseases
0.009 0.991 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.009 0.991 0.000
I78.9 Disease of capillaries, unspecified
0.009 0.991 0.000
M34 Systemic sclerosis
0.009 0.991 0.000
M65.2 Calcific tendinitis
0.009 0.991 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.009 0.991 0.000
M71.3 Other bursal cyst
0.009 0.991 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.009 0.991 0.000
I01.8 Other acute rheumatic heart disease
0.009 0.991 0.000
I01.2 Acute rheumatic myocarditis
0.009 0.991 0.000
I01.1 Acute rheumatic endocarditis
0.009 0.991 0.000
I01.0 Acute rheumatic pericarditis
0.009 0.991 0.000
I02.9 Rheumatic chorea without heart involvement
0.009 0.991 0.000
I02.0 Rheumatic chorea with heart involvement
0.009 0.991 0.000
M85.67 Other cyst of bone (Ankle and foot)
0.009 0.991 0.000
M86-M90 Other osteopathies
0.009 0.991 0.000
M71 Other bursopathies
0.009 0.991 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.009 0.991 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.008 0.991 0.000
M81.9 Osteoporosis, unspecified
0.009 0.991 0.000
M32 Systemic lupus erythematosus
0.009 0.991 0.000
M81.98 Osteoporosis, unspecified (Other)
0.009 0.991 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.008 0.991 0.000
M91-M94 Chondropathies
0.009 0.991 0.000
D89.1 Cryoglobulinaemia
0.008 0.991 0.000
I70.9 Generalised and unspecified atherosclerosis
0.008 0.991 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.008 0.992 0.000
M21.3 Wrist or foot drop (acquired)
0.008 0.992 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.008 0.992 0.000
I70.0 Atherosclerosis of aorta
0.008 0.992 0.000
M85.8 Other specified disorders of bone density and structure
0.008 0.992 0.000
M66 Spontaneous rupture of synovium and tendon
0.008 0.992 0.000
M85.4 Solitary bone cyst
0.008 0.992 0.000
M83 Adult osteomalacia
0.008 0.992 0.000
M21 Other acquired deformities of limbs
0.008 0.992 0.000
M71.38 Other bursal cyst (Other)
0.008 0.992 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.008 0.992 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.008 0.992 0.000
M65.0 Abscess of tendon sheath
0.008 0.992 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.992 0.008
M81.2 Osteoporosis of disuse
0.008 0.992 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.008 0.992 0.000
M71.37 Other bursal cyst (Ankle and foot)
0.008 0.992 0.000
M65.3 Trigger finger
0.008 0.992 0.000
M81.0 Postmenopausal osteoporosis
0.008 0.992 0.000
M65.21 Calcific tendinitis (Shoulder region)
0.008 0.992 0.000
M82.1 Osteoporosis in endocrine disorders
0.008 0.992 0.000
M31 Other necrotising vasculopathies
0.008 0.992 0.000
M81.8 Other osteoporosis
0.008 0.992 0.000
M81.6 Localised osteoporosis [Lequesne]
0.008 0.992 0.000
M81.5 Idiopathic osteoporosis
0.008 0.992 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.008 0.992 0.000
M81.1 Postoophorectomy osteoporosis
0.008 0.992 0.000
I10-I15 Hypertensive diseases
0.008 0.992 0.000
M40-M43 Deforming dorsopathies
0.008 0.992 0.000
M85.2 Hyperostosis of skull
0.008 0.992 0.000
I27 Other pulmonary heart diseases
0.008 0.992 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.008 0.992 0.000
I74 Arterial embolism and thrombosis
0.008 0.992 0.000
I70.1 Atherosclerosis of renal artery
0.008 0.992 0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg
0.008 0.992 0.000
M85.9 Disorder of bone density and structure, unspecified
0.008 0.992 0.000
M85.5 Aneurysmal bone cyst
0.008 0.992 0.000
M85.3 Osteitis condensans
0.008 0.992 0.000
M85.1 Skeletal fluorosis
0.008 0.992 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.008 0.992 0.000
M80.8 Other osteoporosis with pathological fracture
0.007 0.992 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.007 0.992 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.007 0.992 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.007 0.992 0.000
M86 Osteomyelitis
0.008 0.992 0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)
0.007 0.992 0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)
0.007 0.992 0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)
0.007 0.992 0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)
0.007 0.992 0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)
0.007 0.992 0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)
0.007 0.992 0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)
0.007 0.992 0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)
0.007 0.992 0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)
0.007 0.992 0.000
M34.8 Other forms of systemic sclerosis
0.007 0.992 0.000
M34.0 Progressive systemic sclerosis
0.007 0.992 0.000
M65.1 Other infective (teno)synovitis
0.007 0.992 0.000
M93 Other osteochondropathies
0.007 0.992 0.000
S82.5 Fracture of medial malleolus
0.007 0.993 0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)
0.007 0.993 0.000
M71.9 Bursopathy, unspecified
0.007 0.993 0.000
M71.34 Other bursal cyst (Hand)
0.007 0.993 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.007 0.993 0.000
I28 Other diseases of pulmonary vessels
0.007 0.993 0.000
M89 Other disorders of bone
0.007 0.993 0.000
M34.1 CR(E)ST syndrome
0.007 0.993 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.007 0.993 0.000
M33 Dermatopolymyositis
0.007 0.993 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.007 0.993 0.000
M81.48 Drug-induced osteoporosis (Other)
0.007 0.993 0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)
0.007 0.993 0.000
M81.46 Drug-induced osteoporosis (Lower leg)
0.007 0.993 0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)
0.007 0.993 0.000
M81.44 Drug-induced osteoporosis (Hand)
0.007 0.993 0.000
M81.43 Drug-induced osteoporosis (Forearm)
0.007 0.993 0.000
M81.42 Drug-induced osteoporosis (Upper arm)
0.007 0.993 0.000
M81.41 Drug-induced osteoporosis (Shoulder region)
0.007 0.993 0.000
M90 Osteopathies in diseases classified elsewhere
0.007 0.993 0.000
M85.66 Other cyst of bone (Lower leg)
0.007 0.993 0.000
I09.9 Rheumatic heart disease, unspecified
0.007 0.993 0.000
M70-M79 Other soft tissue disorders
0.007 0.993 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.007 0.993 0.000
M36.3 Arthropathy in other blood disorders
0.007 0.993 0.000
M36.2 Haemophilic arthropathy
0.007 0.993 0.000
M36.1 Arthropathy in neoplastic disease
0.007 0.993 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.007 0.993 0.000
M21.33 Wrist or foot drop (acquired) (Forearm)
0.007 0.993 0.000
I09.8 Other specified rheumatic heart diseases
0.007 0.993 0.000
I09.2 Chronic rheumatic pericarditis
0.007 0.993 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.007 0.993 0.000
I09.0 Rheumatic myocarditis
0.007 0.993 0.000
M66.3 Spontaneous rupture of flexor tendons
0.007 0.993 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.007 0.993 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.007 0.993 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.007 0.993 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.007 0.993 0.000
M81.49 Drug-induced osteoporosis (Site unspecified)
0.007 0.993 0.000
I06.1 Rheumatic aortic insufficiency
0.007 0.993 0.000
I73 Other peripheral vascular diseases
0.007 0.993 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.007 0.993 0.000
M21.9 Acquired deformity of limb, unspecified
0.007 0.993 0.000
M85.69 Other cyst of bone (Site unspecified)
0.007 0.993 0.000
M85.68 Other cyst of bone (Other)
0.007 0.993 0.000
M85.64 Other cyst of bone (Hand)
0.007 0.993 0.000
M85.63 Other cyst of bone (Forearm)
0.007 0.993 0.000
M85.62 Other cyst of bone (Upper arm)
0.007 0.993 0.000
M85.61 Other cyst of bone (Shoulder region)
0.007 0.993 0.000
M85.60 Other cyst of bone (Multiple sites)
0.007 0.993 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.007 0.993 0.000
I06.8 Other rheumatic aortic valve diseases
0.007 0.993 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.007 0.993 0.000
M00-M03 Infectious arthropathies
0.007 0.993 0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)
0.007 0.993 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.007 0.993 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.007 0.993 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.007 0.993 0.000
M65.29 Calcific tendinitis (Site unspecified)
0.007 0.993 0.000
M65.28 Calcific tendinitis (Other)
0.007 0.993 0.000
M65.27 Calcific tendinitis (Ankle and foot)
0.007 0.993 0.000
M65.26 Calcific tendinitis (Lower leg)
0.007 0.993 0.000
M65.25 Calcific tendinitis (Pelvic region and thigh)
0.007 0.993 0.000
M65.24 Calcific tendinitis (Hand)
0.007 0.993 0.000
M65.23 Calcific tendinitis (Forearm)
0.007 0.993 0.000
M65.22 Calcific tendinitis (Upper arm)
0.007 0.993 0.000
M65.20 Calcific tendinitis (Multiple sites)
0.007 0.993 0.000
I27.9 Pulmonary heart disease, unspecified
0.007 0.993 0.000
M93.9 Osteochondropathy, unspecified
0.007 0.993 0.000
M66.2 Spontaneous rupture of extensor tendons
0.007 0.993 0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.007 0.993 0.000
M71.39 Other bursal cyst (Site unspecified)
0.007 0.993 0.000
M71.36 Other bursal cyst (Lower leg)
0.007 0.993 0.000
M71.35 Other bursal cyst (Pelvic region and thigh)
0.007 0.993 0.000
M71.33 Other bursal cyst (Forearm)
0.007 0.993 0.000
M71.32 Other bursal cyst (Upper arm)
0.007 0.993 0.000
M71.31 Other bursal cyst (Shoulder region)
0.007 0.993 0.000
M71.30 Other bursal cyst (Multiple sites)
0.007 0.993 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.007 0.993 0.000
M60-M63 Disorders of muscles
0.007 0.993 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.007 0.993 0.000
I06.0 Rheumatic aortic stenosis
0.006 0.993 0.000
M31.8 Other specified necrotising vasculopathies
0.007 0.993 0.000
M18 Arthrosis of first carpometacarpal joint
0.007 0.993 0.000
M89.8 Other specified disorders of bone
0.007 0.993 0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)
0.006 0.993 0.000
M71.8 Other specified bursopathies
0.006 0.993 0.000
M71.5 Other bursitis, not elsewhere classified
0.006 0.993 0.000
M71.4 Calcium deposit in bursa
0.006 0.993 0.000
M71.0 Abscess of bursa
0.006 0.993 0.000
S82.51 Fracture of medial malleolus (open)
0.006 0.993 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.006 0.993 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.006 0.993 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.006 0.993 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.006 0.993 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.006 0.993 0.000
M32.8 Other forms of systemic lupus erythematosus
0.006 0.993 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.006 0.993 0.000
M89.3 Hypertrophy of bone
0.006 0.993 0.000
M71.97 Bursopathy, unspecified (Ankle and foot)
0.006 0.993 0.000
M86.6 Other chronic osteomyelitis
0.006 0.993 0.000
M66.0 Rupture of popliteal cyst
0.006 0.994 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.006 0.994 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.006 0.994 0.000
I10 Essential (primary) hypertension
0.006 0.994 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.006 0.994 0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)
0.006 0.994 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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