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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs597808
log Bayes Factor = 138.181
Chromosome 12   position 111,973,358  (GRCh37) Explore rs597808 on Ensembl!
Variant rs597808 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C77.3 Axillary and upper limb lymph nodes
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.000 1.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
C50 Malignant neoplasm of breast
1.000 0.000 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
I20.9 Angina pectoris, unspecified
0.000 0.001 0.999
Z95.2 Presence of prosthetic heart valve
0.000 0.001 0.999
I20 Angina pectoris
0.000 0.001 0.999
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.002 0.998
Z95.4 Presence of other heart-valve replacement
0.000 0.002 0.998
C50-C50 Malignant neoplasm of breast
0.997 0.003 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.004 0.996
Chapter II Neoplasms
0.994 0.006 0.000
# Top node
0.000 0.006 0.994
D55-D59 Haemolytic anaemias
0.000 0.006 0.994
E10.9 Without complications
0.000 0.006 0.994
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.007 0.993
I74 Arterial embolism and thrombosis
0.000 0.008 0.992
E05.9 Thyrotoxicosis, unspecified
0.000 0.008 0.992
C50.9 Breast, unspecified
0.991 0.009 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.010 0.990
D75 Other diseases of blood and blood-forming organs
0.000 0.010 0.990
I21.9 Acute myocardial infarction, unspecified
0.000 0.012 0.988
C50.4 Upper-outer quadrant of breast
0.988 0.012 0.000
E27 Other disorders of adrenal gland
0.000 0.014 0.986
I22 Subsequent myocardial infarction
0.000 0.018 0.982
E10.5 With peripheral circulatory complications
0.000 0.018 0.982
D75.1 Secondary polycythaemia
0.000 0.019 0.981
I25.5 Ischaemic cardiomyopathy
0.000 0.020 0.980
E06 Thyroiditis
0.000 0.022 0.978
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.976 0.024 0.000
C50.8 Overlapping lesion of breast
0.975 0.025 0.000
C78.7 Secondary malignant neoplasm of liver
0.975 0.025 0.000
D59 Acquired haemolytic anaemia
0.000 0.029 0.971
E27.1 Primary adrenocortical insufficiency
0.000 0.031 0.969
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.969 0.031 0.000
E10.1 With ketoacidosis
0.000 0.035 0.965
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.036 0.964
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.037 0.963
C79 Secondary malignant neoplasm of other sites
0.963 0.037 0.000
E10.3 With ophthalmic complications
0.000 0.041 0.959
E23 Hypofunction and other disorders of pituitary gland
0.000 0.042 0.958
K90 Intestinal malabsorption
0.000 0.044 0.956
D59.1 Other autoimmune haemolytic anaemias
0.000 0.048 0.952
E06.3 Autoimmune thyroiditis
0.000 0.049 0.951
E10.4 With neurological complications
0.000 0.052 0.948
C77.9 Lymph node, unspecified
0.945 0.055 0.000
C50.2 Upper-inner quadrant of breast
0.943 0.057 0.000
D75.2 Essential thrombocytosis
0.000 0.058 0.942
C50.0 Nipple and areola
0.941 0.059 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.059 0.941
Chapter VI Diseases of the nervous system
0.000 0.060 0.940
K90-K93 Other diseases of the digestive system
0.000 0.061 0.939
G81 Hemiplegia
0.000 0.061 0.939
Chapter XI Diseases of the digestive system
0.000 0.062 0.938
G81.9 Hemiplegia, unspecified
0.000 0.062 0.938
K70-K77 Diseases of liver
0.000 0.063 0.937
K74 Fibrosis and cirrhosis of liver
0.000 0.064 0.936
C50.1 Central portion of breast
0.934 0.066 0.000
I73 Other peripheral vascular diseases
0.000 0.068 0.932
M06.9 Rheumatoid arthritis, unspecified
0.000 0.069 0.931
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.071 0.929
K74.3 Primary biliary cirrhosis
0.000 0.074 0.926
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.076 0.924
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.077 0.923
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.920 0.080 0.000
I73.9 Peripheral vascular disease, unspecified
0.000 0.081 0.919
I74.5 Embolism and thrombosis of iliac artery
0.000 0.083 0.917
C84 Peripheral and cutaneous T-cell lymphomas
0.911 0.089 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.090 0.910
D69 Purpura and other haemorrhagic conditions
0.000 0.091 0.909
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.094 0.906
E10.0 With coma
0.000 0.095 0.905
C15-C26 Malignant neoplasms of digestive organs
0.904 0.096 0.000
G20-G26 Extrapyramidal and movement disorders
0.000 0.096 0.904
D58 Other hereditary haemolytic anaemias
0.000 0.098 0.902
I77 Other disorders of arteries and arterioles
0.000 0.099 0.901
K73 Chronic hepatitis, not elsewhere classified
0.000 0.101 0.899
G24 Dystonia
0.000 0.104 0.896
M06 Other rheumatoid arthritis
0.000 0.104 0.896
E10.2 With renal complications
0.000 0.105 0.895
E50-E64 Other nutritional deficiencies
0.000 0.107 0.893
G70-G73 Diseases of myoneural junction and muscle
0.000 0.108 0.892
G83 Other paralytic syndromes
0.000 0.109 0.891
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.110 0.890
D56 Thalassaemia
0.000 0.113 0.887
C79.7 Secondary malignant neoplasm of adrenal gland
0.886 0.114 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.116 0.884
G24.9 Dystonia, unspecified
0.000 0.116 0.884
M05-M14 Inflammatory polyarthropathies
0.000 0.123 0.877
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.125 0.875
E23.2 Diabetes insipidus
0.000 0.127 0.873
C79.8 Secondary malignant neoplasm of other specified sites
0.873 0.127 0.000
E23.6 Other disorders of pituitary gland
0.000 0.128 0.872
C77.8 Lymph nodes of multiple regions
0.870 0.130 0.000
I25.3 Aneurysm of heart
0.000 0.131 0.869
I05-I09 Chronic rheumatic heart diseases
0.000 0.133 0.867
E28 Ovarian dysfunction
0.000 0.134 0.866
I23 Certain current complications following acute myocardial infarction
0.000 0.134 0.866
E34 Other endocrine disorders
0.000 0.135 0.865
M05 Seropositive rheumatoid arthritis
0.000 0.136 0.864
E27.2 Addisonian crisis
0.000 0.142 0.858
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.144 0.856
G83.4 Cauda equina syndrome
0.000 0.146 0.854
C51-C58 Malignant neoplasms of female genital organs
0.854 0.146 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.853 0.147 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.850 0.150 0.000
E07 Other disorders of thyroid
0.000 0.152 0.848
D60-D64 Aplastic and other anaemias
0.000 0.153 0.847
C78.2 Secondary malignant neoplasm of pleura
0.846 0.154 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.155 0.845
K75 Other inflammatory liver diseases
0.000 0.161 0.839
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.163 0.837
M07 Psoriatic and enteropathic arthropathies
0.000 0.163 0.837
C85.7 Other specified types of non-Hodgkin's lymphoma
0.835 0.165 0.000
I77.6 Arteritis, unspecified
0.000 0.169 0.831
D80-D89 Certain disorders involving the immune mechanism
0.000 0.169 0.831
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.170 0.830
K74.0 Hepatic fibrosis
0.000 0.172 0.828
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.174 0.826
C20 Malignant neoplasm of rectum
0.826 0.174 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.175 0.825
E22 Hyperfunction of pituitary gland
0.000 0.176 0.824
I77.1 Stricture of artery
0.000 0.178 0.822
E20 Hypoparathyroidism
0.000 0.178 0.822
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.821 0.179 0.000
I12 Hypertensive renal disease
0.000 0.180 0.820
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.182 0.818
C76 Malignant neoplasm of other and ill-defined sites
0.818 0.182 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.184 0.816
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.184 0.816
K74.5 Biliary cirrhosis, unspecified
0.000 0.187 0.813
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.188 0.812
E06.9 Thyroiditis, unspecified
0.000 0.189 0.811
D69.4 Other primary thrombocytopenia
0.000 0.189 0.811
M07.3 Other psoriatic arthropathies
0.000 0.189 0.811
E27.8 Other specified disorders of adrenal gland
0.000 0.189 0.811
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.189 0.811
E21.3 Hyperparathyroidism, unspecified
0.000 0.190 0.810
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.810 0.190 0.000
C84.0 Mycosis fungoides
0.808 0.192 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.192 0.808
Z95.3 Presence of xenogenic heart valve
0.000 0.193 0.807
C21 Malignant neoplasm of anus and anal canal
0.807 0.193 0.000
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.195 0.805
G72 Other myopathies
0.000 0.195 0.805
D73 Diseases of spleen
0.000 0.199 0.801
G80 Infantile cerebral palsy
0.000 0.200 0.800
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.798 0.202 0.000
E31 Polyglandular dysfunction
0.000 0.202 0.798
C18 Malignant neoplasm of colon
0.797 0.203 0.000
D56.3 Thalassaemia trait
0.000 0.207 0.793
C55 Malignant neoplasm of uterus, part unspecified
0.787 0.213 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.786 0.214 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.215 0.785
G71 Primary disorders of muscles
0.000 0.215 0.785
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.784 0.216 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.217 0.783
C51 Malignant neoplasm of vulva
0.782 0.218 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.781 0.219 0.000
I15 Secondary hypertension
0.000 0.220 0.780
G24.5 Blepharospasm
0.000 0.222 0.778
I07 Rheumatic tricuspid valve diseases
0.000 0.223 0.777
I05 Rheumatic mitral valve diseases
0.000 0.224 0.776
E07.9 Disorder of thyroid, unspecified
0.000 0.226 0.774
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.773 0.227 0.000
K75.4 Autoimmune hepatitis
0.000 0.228 0.772
D86 Sarcoidosis
0.000 0.229 0.771
E03.1 Congenital hypothyroidism without goitre
0.000 0.230 0.770
I25.4 Coronary artery aneurysm
0.000 0.230 0.770
I25.6 Silent myocardial ischaemia
0.000 0.230 0.770
I23.8 Other current complications following acute myocardial infarction
0.000 0.231 0.769
E58 Dietary calcium deficiency
0.000 0.231 0.769
E23.0 Hypopituitarism
0.000 0.234 0.766
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.765 0.235 0.000
C84.4 Peripheral T-cell lymphoma
0.762 0.238 0.000
E03.8 Other specified hypothyroidism
0.000 0.245 0.755
E28.3 Primary ovarian failure
0.000 0.246 0.754
C23 Malignant neoplasm of gallbladder
0.754 0.246 0.000
C18.2 Ascending colon
0.754 0.246 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.752 0.247 0.000
C84.5 Other and unspecified T-cell lymphomas
0.749 0.251 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.253 0.747
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.254 0.746
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.254 0.746
E22.1 Hyperprolactinaemia
0.000 0.254 0.745
C94 Other leukaemias of specified cell type
0.745 0.255 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.258 0.742
G83.9 Paralytic syndrome, unspecified
0.000 0.259 0.741
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.259 0.741
G72.9 Myopathy, unspecified
0.000 0.259 0.741
E53 Deficiency of other B group vitamins
0.000 0.260 0.740
C18.9 Colon, unspecified
0.738 0.262 0.000
L40.5 Arthropathic psoriasis
0.000 0.266 0.734
C86 Other specified types of T/NK-cell lymphoma
0.733 0.267 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.732 0.268 0.000
L40 Psoriasis
0.000 0.269 0.731
C51.9 Vulva, unspecified
0.730 0.270 0.000
C77.2 Intra-abdominal lymph nodes
0.727 0.273 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.274 0.726
E06.1 Subacute thyroiditis
0.000 0.275 0.725
I21.4 Acute subendocardial myocardial infarction
0.000 0.275 0.725
L40-L45 Papulosquamous disorders
0.000 0.276 0.724
K74.6 Other and unspecified cirrhosis of liver
0.000 0.276 0.724
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.282 0.718
K73.9 Chronic hepatitis, unspecified
0.000 0.283 0.717
E34.0 Carcinoid syndrome
0.000 0.283 0.717
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.283 0.717
E30 Disorders of puberty, not elsewhere classified
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E25 Adrenogenital disorders
0.000 0.284 0.716
C21.8 Overlapping lesion of rectum, anus and anal canal
0.715 0.285 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.286 0.714
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.286 0.714
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.286 0.714
E34.9 Endocrine disorder, unspecified
0.000 0.287 0.713
I07.1 Tricuspid insufficiency
0.000 0.287 0.713
D55 Anaemia due to enzyme disorders
0.000 0.287 0.713
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.288 0.712
E05.5 Thyroid crisis or storm
0.000 0.288 0.712
E05.4 Thyrotoxicosis factitia
0.000 0.288 0.712
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.288 0.712
D86.9 Sarcoidosis, unspecified
0.000 0.290 0.710
D74 Methaemoglobinaemia
0.000 0.290 0.710
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.290 0.710
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.290 0.710
D57 Sickle-cell disorders
0.000 0.290 0.710
D58.0 Hereditary spherocytosis
0.000 0.290 0.710
E40-E46 Malnutrition
0.000 0.291 0.709
G80.9 Infantile cerebral palsy, unspecified
0.000 0.293 0.707
E27.5 Adrenomedullary hyperfunction
0.000 0.293 0.707
E27.0 Other adrenocortical overactivity
0.000 0.293 0.707
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.295 0.705
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.296 0.704
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.296 0.704
M12 Other specific arthropathies
0.000 0.296 0.704
E10.8 With unspecified complications
0.000 0.296 0.703
C49 Malignant neoplasm of other connective and soft tissue
0.702 0.298 0.000
I05.0 Mitral stenosis
0.000 0.298 0.702
D75.0 Familial erythrocytosis
0.000 0.299 0.701
E06.4 Drug-induced thyroiditis
0.000 0.299 0.701
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.299 0.701
E06.0 Acute thyroiditis
0.000 0.299 0.701
C97 Malignant neoplasms of independent (primary) multiple sites
0.697 0.303 0.000
D59.8 Other acquired haemolytic anaemias
0.000 0.304 0.696
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.304 0.696
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.304 0.696
D59.3 Haemolytic-uraemic syndrome
0.000 0.304 0.696
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.304 0.696
I13 Hypertensive heart and renal disease
0.000 0.304 0.695
E20.9 Hypoparathyroidism, unspecified
0.000 0.305 0.695
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.694 0.306 0.000
E32 Diseases of thymus
0.000 0.306 0.694
C78.4 Secondary malignant neoplasm of small intestine
0.693 0.307 0.000
C76.0 Head, face and neck
0.693 0.307 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.309 0.691
D73.3 Abscess of spleen
0.000 0.310 0.690
G24.1 Idiopathic familial dystonia
0.000 0.311 0.689
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.312 0.688
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.313 0.687
E23.1 Drug-induced hypopituitarism
0.000 0.313 0.687
I77.2 Rupture of artery
0.000 0.313 0.686
K71 Toxic liver disease
0.000 0.314 0.686
I05.2 Mitral stenosis with insufficiency
0.000 0.314 0.686
K90.3 Pancreatic steatorrhoea
0.000 0.315 0.685
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.315 0.685
K90.1 Tropical sprue
0.000 0.315 0.685
G25 Other extrapyramidal and movement disorders
0.000 0.316 0.684
D56.1 Beta thalassaemia
0.000 0.316 0.684
I77.0 Arteriovenous fistula, acquired
0.000 0.318 0.682
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.321 0.679
E10.6 With other specified complications
0.000 0.321 0.679
E61 Deficiency of other nutrient elements
0.000 0.321 0.679
K40-K46 Hernia
0.000 0.322 0.678
K90.8 Other intestinal malabsorption
0.000 0.322 0.677
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.323 0.677
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.323 0.677
C95 Leukaemia of unspecified cell type
0.676 0.324 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.325 0.675
C88 Malignant immunoproliferative diseases
0.674 0.326 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.327 0.673
G81.0 Flaccid hemiplegia
0.000 0.327 0.673
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.673 0.327 0.000
E51 Thiamine deficiency
0.000 0.328 0.672
I22.8 Subsequent myocardial infarction of other sites
0.000 0.329 0.671
K74.4 Secondary biliary cirrhosis
0.000 0.329 0.671
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.329 0.671
C77.4 Inguinal and lower limb lymph nodes
0.670 0.330 0.000
E06.5 Other chronic thyroiditis
0.000 0.330 0.670
K77 Liver disorders in diseases classified elsewhere
0.000 0.330 0.670
C17 Malignant neoplasm of small intestine
0.669 0.331 0.000
D58.2 Other haemoglobinopathies
0.000 0.332 0.668
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.667 0.333 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.333 0.667
G71.1 Myotonic disorders
0.000 0.333 0.667
E55 Vitamin D deficiency
0.000 0.334 0.666
C26.9 Ill-defined sites within the digestive system
0.665 0.335 0.000
C93 Monocytic leukaemia
0.664 0.336 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.337 0.663
C90.1 Plasma cell leukaemia
0.662 0.338 0.000
D86.0 Sarcoidosis of lung
0.000 0.338 0.662
C85.0 Lymphosarcoma
0.660 0.340 0.000
G70 Myasthenia gravis and other myoneural disorders
0.000 0.341 0.659
G24.3 Spasmodic torticollis
0.000 0.341 0.659
C81 Hodgkin's disease
0.658 0.342 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.343 0.657
E26 Hyperaldosteronism
0.000 0.344 0.656
E21.0 Primary hyperparathyroidism
0.000 0.344 0.656
I00-I02 Acute rheumatic fever
0.000 0.344 0.656
L40.9 Psoriasis, unspecified
0.000 0.344 0.656
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.344 0.655
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.346 0.654
E31.0 Autoimmune polyglandular failure
0.000 0.346 0.654
M05.1 Rheumatoid lung disease
0.000 0.347 0.653
C84.9 Mature T/NK-cell lymphoma, unspecified
0.653 0.347 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.653 0.347 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.653 0.347 0.000
C84.3 Lymphoepithelioid lymphoma
0.653 0.347 0.000
C84.2 T-zone lymphoma
0.653 0.347 0.000
C84.1 Sezary's diease
0.653 0.347 0.000
G80.2 Infantile hemiplegia
0.000 0.347 0.653
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.348 0.652
G83.1 Monoplegia of lower limb
0.000 0.349 0.651
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.350 0.650
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.350 0.650
D69.8 Other specified haemorrhagic conditions
0.000 0.350 0.650
I12.9 Hypertensive renal disease without renal failure
0.000 0.350 0.650
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.000 0.352 0.648
G22 Parkinsonism in diseases classified elsewhere
0.000 0.352 0.648
C18.3 Hepatic flexure
0.647 0.353 0.000
E14 Unspecified diabetes mellitus
0.000 0.353 0.647
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.353 0.646
D58.1 Hereditary elliptocytosis
0.000 0.353 0.646
I77.5 Necrosis of artery
0.000 0.354 0.646
I77.4 Coeliac artery compression syndrome
0.000 0.354 0.646
K41 Femoral hernia
0.000 0.355 0.645
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.356 0.644
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.356 0.644
I12.0 Hypertensive renal disease with renal failure
0.000 0.356 0.644
I70 Atherosclerosis
0.000 0.356 0.644
G24.4 Idiopathic orofacial dystonia
0.000 0.357 0.643
G24.2 Idiopathic nonfamilial dystonia
0.000 0.357 0.643
M06.2 Rheumatoid bursitis
0.000 0.358 0.642
M06.1 Adult-onset Still's disease
0.000 0.358 0.642
I20.8 Other forms of angina pectoris
0.000 0.358 0.642
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.642 0.358 0.000
D66 Hereditary factor VIII deficiency
0.000 0.358 0.642
C49.3 Connective and soft tissue of thorax
0.641 0.359 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.359 0.640
E63 Other nutritional deficiencies
0.000 0.359 0.640
E50 Vitamin A deficiency
0.000 0.359 0.640
E60 Dietary zinc deficiency
0.000 0.359 0.640
E59 Dietary selenium deficiency
0.000 0.359 0.640
E52 Niacin deficiency [pellagra]
0.000 0.359 0.640
C21.0 Anus, unspecified
0.640 0.360 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.360 0.640
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.360 0.640
G83.5 Locked-in syndrome
0.000 0.361 0.639
G83.3 Monoplegia, unspecified
0.000 0.361 0.639
G83.0 Diplegia of upper limbs
0.000 0.361 0.639
K74.1 Hepatic sclerosis
0.000 0.363 0.637
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.363 0.637
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.363 0.637
D56.9 Thalassaemia, unspecified
0.000 0.364 0.636
D56.8 Other thalassaemias
0.000 0.364 0.636
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.364 0.636
D56.2 Delta-beta thalassaemia
0.000 0.364 0.636
D56.0 Alpha thalassaemia
0.000 0.364 0.636
G72.8 Other specified myopathies
0.000 0.364 0.636
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.364 0.636
D73.4 Cyst of spleen
0.000 0.365 0.635
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.365 0.635
D73.1 Hypersplenism
0.000 0.367 0.633
C82.0 Small cleaved cell, follicular
0.631 0.369 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.369 0.631
E21.2 Other hyperparathyroidism
0.000 0.369 0.631
K90.9 Intestinal malabsorption, unspecified
0.000 0.370 0.630
M08 Juvenile arthritis
0.000 0.371 0.629
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.371 0.629
D83 Common variable immunodeficiency
0.000 0.371 0.629
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.372 0.628
G23 Other degenerative diseases of basal ganglia
0.000 0.373 0.627
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.375 0.625
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.625 0.375 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.625 0.375 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.376 0.624
E10.7 With multiple complications
0.000 0.376 0.624
C76.1 Thorax
0.622 0.378 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.379 0.621
E28.8 Other ovarian dysfunction
0.000 0.379 0.621
E28.1 Androgen excess
0.000 0.379 0.621
E28.0 Oestrogen excess
0.000 0.379 0.621
I20.1 Angina pectoris with documented spasm
0.000 0.379 0.621
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.379 0.621
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.379 0.621
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.379 0.621
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.379 0.621
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.379 0.621
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.379 0.621
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.379 0.621
E34.5 Androgen resistance syndrome
0.000 0.379 0.620
E34.4 Constitutional tall stature
0.000 0.379 0.620
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.379 0.620
E34.1 Other hypersecretion of intestinal hormones
0.000 0.379 0.620
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.380 0.620
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.380 0.620
M05.0 Felty's syndrome
0.000 0.380 0.620
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.381 0.619
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.619 0.381 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.381 0.618
I15.1 Hypertension secondary to other renal disorders
0.000 0.382 0.618
C54 Malignant neoplasm of corpus uteri
0.618 0.382 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.382 0.618
D73.9 Disease of spleen, unspecified
0.000 0.383 0.617
M05.8 Other seropositive rheumatoid arthritis
0.000 0.383 0.617
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.384 0.615
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.386 0.614
E05.8 Other thyrotoxicosis
0.000 0.386 0.614
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.386 0.614
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.386 0.614
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.386 0.614
D69.9 Haemorrhagic condition, unspecified
0.000 0.387 0.613
I26 Pulmonary embolism
0.000 0.387 0.613
G24.8 Other dystonia
0.000 0.387 0.613
G24.0 Drug-induced dystonia
0.000 0.387 0.613
C58 Malignant neoplasm of placenta
0.612 0.388 0.000
G71.0 Muscular dystrophy
0.000 0.389 0.611
E34.8 Other specified endocrine disorders
0.000 0.389 0.611
D82 Immunodeficiency associated with other major defects
0.000 0.390 0.610
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.609 0.391 0.000
C49.1 Connective and soft tissue of upper limb, including shoulder
0.609 0.391 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.391 0.609
E07.1 Dyshormogenetic goitre
0.000 0.392 0.608
E07.0 Hypersecretion of calcitonin
0.000 0.392 0.608
K44 Diaphragmatic hernia
0.000 0.392 0.608
D67 Hereditary factor IX deficiency
0.000 0.393 0.607
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.393 0.607
M06.8 Other specified rheumatoid arthritis
0.000 0.396 0.604
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.396 0.604
E56 Other vitamin deficiencies
0.000 0.397 0.603
E27.9 Disorder of adrenal gland, unspecified
0.000 0.397 0.603
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.398 0.602
K75.2 Nonspecific reactive hepatitis
0.000 0.399 0.601
K75.1 Phlebitis of portal vein
0.000 0.399 0.601
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.399 0.601
M10 Gout
0.000 0.400 0.600
M07.5 Arthropathy in ulcerative colitis
0.000 0.400 0.600
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.400 0.600
M07.2 Psoriatic spondylitis
0.000 0.400 0.600
M07.1 Arthritis mutilans
0.000 0.400 0.600
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.400 0.600
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.400 0.600
M06.3 Rheumatoid nodule
0.000 0.402 0.598
I15.0 Renovascular hypertension
0.000 0.404 0.596
D81 Combined immunodeficiencies
0.000 0.404 0.596
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.404 0.595
K75.8 Other specified inflammatory liver diseases
0.000 0.405 0.595
C57 Malignant neoplasm of other and unspecified female genital organs
0.594 0.406 0.000
C79.2 Secondary malignant neoplasm of skin
0.594 0.406 0.000
M12.2 Villonodular synovitis (pigmented)
0.000 0.408 0.592
E22.8 Other hyperfunction of pituitary gland
0.000 0.409 0.591
G80.0 Spastic cerebral palsy
0.000 0.409 0.591
I78 Diseases of capillaries
0.000 0.409 0.591
C40-C41 Malignant neoplasms of bone and articular cartilage
0.590 0.409 0.000
C80 Malignant neoplasm without specification of site
0.590 0.409 0.000
E20.8 Other hypoparathyroidism
0.000 0.410 0.589
E20.1 Pseudohypoparathyroidism
0.000 0.410 0.589
E20.0 Idiopathic hypoparathyroidism
0.000 0.410 0.589
C74 Malignant neoplasm of adrenal gland
0.589 0.411 0.000
I77.3 Arterial fibromuscular dysplasia
0.000 0.411 0.589
C90.2 Plasmacytoma, extramedullary
0.588 0.412 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.413 0.587

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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