TreeWAS – Variant ID: rs2301756

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I21 Acute myocardial infarction	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.008	0.992
I21.9 Acute myocardial infarction, unspecified	0.000	0.019	0.981
I25.2 Old myocardial infarction	0.000	0.039	0.961
I22 Subsequent myocardial infarction	0.000	0.084	0.916
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.121	0.879
I21.4 Acute subendocardial myocardial infarction	0.000	0.198	0.802
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.209	0.791
I25.5 Ischaemic cardiomyopathy	0.000	0.210	0.790
I24 Other acute ischaemic heart diseases	0.000	0.258	0.742
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.273	0.727
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.283	0.717
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.302	0.698
I25.3 Aneurysm of heart	0.000	0.309	0.691
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.356	0.644
I25.4 Coronary artery aneurysm	0.000	0.365	0.635
I23 Certain current complications following acute myocardial infarction	0.000	0.367	0.633
I20 Angina pectoris	0.000	0.370	0.630
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.391	0.609
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.394	0.606
I20.9 Angina pectoris, unspecified	0.000	0.398	0.602
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.407	0.593
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.407	0.593
I22.8 Subsequent myocardial infarction of other sites	0.000	0.408	0.592
I24.8 Other forms of acute ischaemic heart disease	0.000	0.412	0.588
Z95.4 Presence of other heart-valve replacement	0.000	0.415	0.585
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.433	0.567
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.445	0.555
Z95.3 Presence of xenogenic heart valve	0.000	0.458	0.542
I24.1 Dressler's syndrome	0.000	0.468	0.532
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.478	0.521
Z95.1 Presence of aortocoronary bypass graft	0.000	0.520	0.480
Z95.2 Presence of prosthetic heart valve	0.000	0.540	0.460
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.546	0.454
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.546	0.454
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.546	0.454
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.546	0.454
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.546	0.454
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.546	0.454
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.546	0.454
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.615	0.385
I23.8 Other current complications following acute myocardial infarction	0.001	0.630	0.369
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.644	0.356
I20.8 Other forms of angina pectoris	0.000	0.665	0.335
I20.1 Angina pectoris with documented spasm	0.000	0.686	0.314
Z95.0 Presence of cardiac pacemaker	0.000	0.760	0.240
M20-M25 Other joint disorders	0.239	0.761	0.000
M24 Other specific joint derangements	0.238	0.762	0.000
M25 Other joint disorders, not elsewhere classified	0.234	0.766	0.000
M22 Disorders of patella	0.232	0.768	0.000
M24.2 Disorder of ligament	0.227	0.773	0.000
M20 Acquired deformities of fingers and toes	0.224	0.776	0.000
M24.0 Loose body in joint	0.224	0.776	0.000
M22.4 Chondromalacia patellae	0.219	0.781	0.000
M25.3 Other instability of joint	0.217	0.783	0.000
M25.4 Effusion of joint	0.217	0.783	0.000
M24.23 Disorder of ligament (Forearm)	0.214	0.786	0.000
M20.0 Deformity of finger(s)	0.211	0.789	0.000
M34 Systemic sclerosis	0.209	0.791	0.000
M25.0 Haemarthrosis	0.207	0.793	0.000
M20.5 Other deformities of toe(s) (acquired)	0.206	0.794	0.000
M24.02 Loose body in joint (Upper arm)	0.201	0.799	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.200	0.799	0.000
M25.42 Effusion of joint (Upper arm)	0.199	0.801	0.000
M22.3 Other derangements of patella	0.199	0.801	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.197	0.803	0.000
M25.31 Other instability of joint (Shoulder region)	0.190	0.810	0.000
M25.8 Other specified joint disorders	0.189	0.811	0.000
M25.06 Haemarthrosis (Lower leg)	0.188	0.812	0.000
M21 Other acquired deformities of limbs	0.184	0.816	0.000
M24.07 Loose body in joint (Ankle and foot)	0.183	0.817	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.179	0.820	0.000
M34.9 Systemic sclerosis, unspecified	0.179	0.821	0.000
M24.26 Disorder of ligament (Lower leg)	0.177	0.823	0.000
M24.28 Disorder of ligament (Other)	0.176	0.824	0.000
M24.03 Loose body in joint (Forearm)	0.176	0.824	0.000
M31 Other necrotising vasculopathies	0.175	0.825	0.000
M25.36 Other instability of joint (Lower leg)	0.174	0.826	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.174	0.826	0.000
M22.8 Other disorders of patella	0.173	0.827	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.173	0.827	0.000
M25.9 Joint disorder, unspecified	0.173	0.827	0.000
M24.21 Disorder of ligament (Shoulder region)	0.172	0.828	0.000
M24.5 Contracture of joint	0.172	0.828	0.000
M25.47 Effusion of joint (Ankle and foot)	0.171	0.829	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.171	0.829	0.000
M24.9 Joint derangement, unspecified	0.171	0.829	0.000
M24.7 Protrusio acetabuli	0.171	0.829	0.000
M24.6 Ankylosis of joint	0.171	0.829	0.000
M22.2 Patellofemoral disorders	0.171	0.829	0.000
M32 Systemic lupus erythematosus	0.170	0.830	0.000
M25.2 Flail joint	0.168	0.832	0.000
M25.1 Fistula of joint	0.168	0.832	0.000
M20.2 Hallux rigidus	0.167	0.833	0.000
M22.1 Recurrent subluxation of patella	0.166	0.834	0.000
M22.9 Disorder of patella, unspecified	0.166	0.834	0.000
M22.0 Recurrent dislocation of patella	0.166	0.834	0.000
M25.34 Other instability of joint (Hand)	0.166	0.834	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.166	0.834	0.000
M33 Dermatopolymyositis	0.165	0.834	0.000
M24.01 Loose body in joint (Shoulder region)	0.165	0.835	0.000
M25.33 Other instability of joint (Forearm)	0.165	0.835	0.000
M25.37 Other instability of joint (Ankle and foot)	0.164	0.835	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.164	0.836	0.000
M24.29 Disorder of ligament (Site unspecified)	0.163	0.837	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.163	0.837	0.000
M24.22 Disorder of ligament (Upper arm)	0.163	0.837	0.000
M24.20 Disorder of ligament (Multiple sites)	0.163	0.837	0.000
M34.8 Other forms of systemic sclerosis	0.161	0.839	0.000
M24.09 Loose body in joint (Site unspecified)	0.161	0.839	0.000
M24.08 Loose body in joint (Other)	0.161	0.839	0.000
M24.06 Loose body in joint-Lower leg	0.161	0.839	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.161	0.839	0.000
M24.04 Loose body in joint (Hand)	0.161	0.839	0.000
M24.00 Loose body in joint (Multiple sites)	0.161	0.839	0.000
M24.24 Disorder of ligament (Hand)	0.160	0.840	0.000
Chapter IX Diseases of the circulatory system	0.000	0.840	0.160
M25.88 Other specified joint disorders (Other)	0.159	0.841	0.000
M34.1 CR(E)ST syndrome	0.158	0.842	0.000
M25.39 Other instability of joint (Site unspecified)	0.156	0.844	0.000
M25.38 Other instability of joint (Other)	0.156	0.844	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.156	0.844	0.000
M25.32 Other instability of joint (Upper arm)	0.156	0.844	0.000
M25.30 Other instability of joint (Multiple sites)	0.156	0.844	0.000
M25.49 Effusion of joint (Site unspecified)	0.155	0.844	0.000
M25.48 Effusion of joint (Other)	0.155	0.844	0.000
M25.44 Effusion of joint (Hand)	0.155	0.844	0.000
M25.43 Effusion of joint (Forearm)	0.155	0.844	0.000
M25.41 Effusion of joint (Shoulder region)	0.155	0.844	0.000
M25.40 Effusion of joint (Multiple sites)	0.154	0.846	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.153	0.847	0.000
I05-I09 Chronic rheumatic heart diseases	0.000	0.847	0.153
M30 Polyarteritis nodosa and related conditions	0.152	0.848	0.000
M25.46 Effusion of joint (Lower leg)	0.152	0.848	0.000
M25.86 Other specified joint disorders (Lower leg)	0.151	0.849	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.151	0.849	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.150	0.850	0.000
M34.0 Progressive systemic sclerosis	0.150	0.850	0.000
I10-I15 Hypertensive diseases	0.000	0.850	0.150
M25.09 Haemarthrosis (Site unspecified)	0.149	0.851	0.000
M25.08 Haemarthrosis (Other)	0.149	0.851	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.149	0.851	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.149	0.851	0.000
M25.04 Haemarthrosis (Hand)	0.149	0.851	0.000
M25.03 Haemarthrosis (Forearm)	0.149	0.851	0.000
M25.02 Haemarthrosis (Upper arm)	0.149	0.851	0.000
M25.01 Haemarthrosis (Shoulder region)	0.149	0.851	0.000
M25.00 Haemarthrosis (Multiple sites)	0.149	0.851	0.000
M21.3 Wrist or foot drop (acquired)	0.149	0.851	0.000
M31.6 Other giant cell arteritis	0.147	0.853	0.000
M21.0 Valgus deformity, not elsewhere classified	0.147	0.853	0.000
I10 Essential (primary) hypertension	0.000	0.853	0.147
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.146	0.854	0.000
M21.7 Unequal limb length (acquired)	0.145	0.855	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.144	0.856	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.144	0.856	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.144	0.856	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.144	0.856	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.144	0.856	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.144	0.856	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.144	0.856	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.144	0.856	0.000
I08 Multiple valve diseases	0.000	0.857	0.143
M25.81 Other specified joint disorders (Shoulder region)	0.141	0.859	0.000
M24.1 Other articular cartilage disorders	0.141	0.859	0.000
M25.7 Osteophyte	0.141	0.859	0.000
M21.6 Other acquired deformities of ankle and foot	0.139	0.861	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.136	0.864	0.000
M25.83 Other specified joint disorders (Forearm)	0.136	0.864	0.000
M25.82 Other specified joint disorders (Upper arm)	0.136	0.864	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.136	0.864	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.135	0.865	0.000
I05 Rheumatic mitral valve diseases	0.000	0.865	0.135
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.132	0.868	0.000
M21.9 Acquired deformity of limb, unspecified	0.132	0.868	0.000
M21.8 Other specified acquired deformities of limbs	0.132	0.868	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.869	0.131
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.131	0.869	0.000
M21.4 Flat foot [pes planus] (acquired)	0.129	0.871	0.000
M20.1 Hallux valgus (acquired)	0.129	0.871	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.127	0.873	0.000
M31.9 Necrotising vasculopathy, unspecified	0.125	0.874	0.000
M31.8 Other specified necrotising vasculopathies	0.125	0.874	0.000
M31.7 Microscopic polyangiitis	0.125	0.874	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.125	0.874	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.125	0.874	0.000
M31.2 Lethal midline granuloma	0.125	0.874	0.000
M31.1 Thrombotic microangiopathy	0.125	0.874	0.000
M31.0 Hypersensitivity angiitis	0.125	0.874	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.125	0.875	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.125	0.875	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.125	0.875	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.125	0.875	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.124	0.875	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.124	0.875	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.124	0.875	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.124	0.875	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.124	0.875	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.124	0.875	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.124	0.875	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.124	0.875	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.124	0.875	0.000
M24.54 Contracture of joint (Hand)	0.124	0.876	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.124	0.876	0.000
M25.98 Joint disorder, unspecified (Other)	0.124	0.876	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.124	0.876	0.000
M25.94 Joint disorder, unspecified (Hand)	0.124	0.876	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.124	0.876	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.124	0.876	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.124	0.876	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.124	0.876	0.000
M25.74 Osteophyte (Hand)	0.124	0.876	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.124	0.876	0.000
M24.59 Contracture of joint (Site unspecified)	0.123	0.877	0.000
M24.58 Contracture of joint (Other)	0.123	0.877	0.000
M24.57 Contracture of joint (Ankle and foot)	0.123	0.877	0.000
M24.56 Contracture of joint (Lower leg)	0.123	0.877	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.123	0.877	0.000
M24.53 Contracture of joint (Forearm)	0.123	0.877	0.000
M24.52 Contracture of joint (Upper arm)	0.123	0.877	0.000
M24.51 Contracture of joint (Shoulder region)	0.123	0.877	0.000
M24.50 Contracture of joint (Multiple sites)	0.123	0.877	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.123	0.877	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.123	0.877	0.000
M36.3 Arthropathy in other blood disorders	0.123	0.877	0.000
M36.2 Haemophilic arthropathy	0.123	0.877	0.000
M36.1 Arthropathy in neoplastic disease	0.123	0.877	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.123	0.877	0.000
M25.84 Other specified joint disorders (Hand)	0.123	0.877	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.122	0.877	0.000
M24.68 Ankylosis of joint (Other)	0.122	0.877	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.122	0.877	0.000
M24.66 Ankylosis of joint (Lower leg)	0.122	0.877	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.122	0.877	0.000
M24.64 Ankylosis of joint (Hand)	0.122	0.877	0.000
M24.63 Ankylosis of joint (Forearm)	0.122	0.877	0.000
M24.62 Ankylosis of joint (Upper arm)	0.122	0.877	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.122	0.877	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.122	0.877	0.000
M24.79 Protrusio acetabuli-Site unspec	0.122	0.877	0.000
M24.78 Protrusio acetabuli-Other	0.122	0.877	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.122	0.877	0.000
M24.76 Protrusio acetabuli-Lower leg	0.122	0.877	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.122	0.877	0.000
M24.74 Protrusio acetabuli-Hand	0.122	0.877	0.000
M24.73 Protrusio acetabuli-Forearm	0.122	0.877	0.000
M24.72 Protrusio acetabuli-Upper arm	0.122	0.877	0.000
M24.71 Protrusio acetabuli-Shldr region	0.122	0.877	0.000
M24.70 Protrusio acetabuli-Mult sites	0.122	0.877	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.122	0.877	0.000
M24.98 Joint derangement, unspecified (Other)	0.122	0.877	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.122	0.877	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.122	0.877	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.122	0.877	0.000
M24.94 Joint derangement, unspecified (Hand)	0.122	0.877	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.122	0.877	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.122	0.877	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.122	0.877	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.122	0.877	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.122	0.878	0.000
M32.8 Other forms of systemic lupus erythematosus	0.122	0.878	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.122	0.878	0.000
M25.72 Osteophyte (Upper arm)	0.122	0.878	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.122	0.878	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.121	0.878	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.879	0.121
M25.19 Fistula of joint (Site unspecified)	0.120	0.879	0.000
M25.18 Fistula of joint (Other)	0.120	0.879	0.000
M25.17 Fistula of joint (Ankle and foot)	0.120	0.879	0.000
M25.16 Fistula of joint (Lower leg)	0.120	0.879	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.120	0.879	0.000
M25.14 Fistula of joint (Hand)	0.120	0.879	0.000
M25.13 Fistula of joint (Forearm)	0.120	0.879	0.000
M25.12 Fistula of joint (Upper arm)	0.120	0.879	0.000
M25.11 Fistula of joint (Shoulder region)	0.120	0.879	0.000
M25.10 Fistula of joint (Multiple sites)	0.120	0.879	0.000
M25.29 Flail joint (Site unspecified)	0.120	0.879	0.000
M25.28 Flail joint (Other)	0.120	0.879	0.000
M25.27 Flail joint (Ankle and foot)	0.120	0.879	0.000
M25.26 Flail joint (Lower leg)	0.120	0.879	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.120	0.879	0.000
M25.24 Flail joint (Hand)	0.120	0.879	0.000
M25.23 Flail joint (Forearm)	0.120	0.879	0.000
M25.22 Flail joint (Upper arm)	0.120	0.879	0.000
M25.21 Flail joint (Shoulder region)	0.120	0.879	0.000
M25.20 Flail joint (Multiple sites)	0.120	0.879	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.880	0.120
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.120	0.880	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.120	0.880	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.119	0.880	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.881	0.119
M33.9 Dermatopolymyositis, unspecified	0.119	0.881	0.000
M33.2 Polymyositis	0.119	0.881	0.000
M33.0 Juvenile dermatomyositis	0.119	0.881	0.000
M21.1 Varus deformity, not elsewhere classified	0.117	0.883	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.117	0.883	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.117	0.883	0.000
M25.78 Osteophyte (Other)	0.116	0.884	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.115	0.884	0.000
I05.0 Mitral stenosis	0.000	0.885	0.115
I00-I02 Acute rheumatic fever	0.000	0.885	0.115
M33.1 Other dermatomyositis	0.113	0.887	0.000
I73 Other peripheral vascular diseases	0.000	0.887	0.113
I07 Rheumatic tricuspid valve diseases	0.000	0.887	0.113
I06 Rheumatic aortic valve diseases	0.000	0.890	0.110
M30.0 Polyarteritis nodosa	0.109	0.891	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.109	0.891	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.109	0.891	0.000
M30.2 Juvenile polyarteritis	0.109	0.891	0.000
M21.2 Flexion deformity	0.109	0.891	0.000
I12 Hypertensive renal disease	0.000	0.892	0.108
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.108	0.892	0.000
I13 Hypertensive heart and renal disease	0.000	0.892	0.108
M24.13 Other articular cartilage disorders (Forearm)	0.107	0.893	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.107	0.893	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.107	0.893	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.107	0.893	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.107	0.893	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.107	0.893	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.107	0.893	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.107	0.893	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.107	0.893	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.107	0.893	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.107	0.893	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.106	0.894	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.106	0.894	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.894	0.106
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.105	0.895	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.105	0.895	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.105	0.895	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.105	0.895	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.105	0.895	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.105	0.895	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.105	0.895	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.105	0.895	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.104	0.896	0.000
M21.78 Unequal limb length (acquired)-Other	0.104	0.896	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.104	0.896	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.104	0.896	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.104	0.896	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.104	0.896	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.104	0.896	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.104	0.896	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.104	0.896	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.103	0.896	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.103	0.896	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.103	0.896	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.103	0.896	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.103	0.896	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.103	0.896	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.103	0.896	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.103	0.896	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.103	0.896	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.102	0.897	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.898	0.102
I73.0 Raynaud's syndrome	0.000	0.898	0.102
M24.19 Other articular cartilage disorders (Site unspecified)	0.101	0.899	0.000
M24.18 Other articular cartilage disorders (Other)	0.101	0.899	0.000
M24.14 Other articular cartilage disorders (Hand)	0.101	0.899	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.101	0.899	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.101	0.899	0.000
M25.79 Osteophyte (Site unspecified)	0.101	0.899	0.000
M25.73 Osteophyte (Forearm)	0.101	0.899	0.000
M25.70 Osteophyte (Multiple sites)	0.101	0.899	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.899	0.101
I09 Other rheumatic heart diseases	0.000	0.900	0.100
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.100	0.900	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.100	0.900	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.100	0.900	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.100	0.900	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.100	0.900	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.100	0.900	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.100	0.900	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.100	0.900	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.100	0.900	0.000
I71 Aortic aneurysm and dissection	0.000	0.901	0.099
I12.9 Hypertensive renal disease without renal failure	0.000	0.902	0.098
I05.9 Mitral valve disease, unspecified	0.000	0.903	0.097
M20.3 Other deformity of hallux (acquired)	0.097	0.903	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.903	0.097
I05.8 Other mitral valve diseases	0.000	0.903	0.097
I15 Secondary hypertension	0.000	0.904	0.096
I73.9 Peripheral vascular disease, unspecified	0.000	0.904	0.096
I11 Hypertensive heart disease	0.000	0.905	0.095
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.095	0.905	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.095	0.905	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.095	0.905	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.095	0.905	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.095	0.905	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.095	0.905	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.095	0.905	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.095	0.905	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.095	0.905	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.095	0.905	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.095	0.905	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.095	0.905	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.095	0.905	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.095	0.905	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.095	0.905	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.095	0.905	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.095	0.905	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.095	0.905	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.095	0.905	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.095	0.905	0.000
M31.3 Wegener's granulomatosis	0.093	0.906	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.093	0.907	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.093	0.907	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.093	0.907	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.093	0.907	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.093	0.907	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.093	0.907	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.093	0.907	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.093	0.907	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.093	0.907	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.091	0.909	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.090	0.910	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.090	0.910	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.089	0.911	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.088	0.912	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.913	0.087
I78 Diseases of capillaries	0.000	0.913	0.087
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.086	0.914	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.086	0.914	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.086	0.914	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.086	0.914	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.086	0.914	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.086	0.914	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.086	0.914	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.086	0.914	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.086	0.914	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.914	0.086
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.914	0.086
I08.8 Other multiple valve diseases	0.000	0.914	0.085
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.085	0.914	0.000
M25.71 Osteophyte (Shoulder region)	0.085	0.915	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.084	0.915	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.084	0.916	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.084	0.916	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.084	0.916	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.084	0.916	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.084	0.916	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.084	0.916	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.084	0.916	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.084	0.916	0.000
I07.1 Tricuspid insufficiency	0.000	0.916	0.084
I02 Rheumatic chorea	0.000	0.918	0.082
I01 Rheumatic fever with heart involvement	0.000	0.918	0.082
I00 Rheumatic fever without mention of heart involvement	0.000	0.918	0.082
I73.8 Other specified peripheral vascular diseases	0.000	0.919	0.081
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.919	0.081
I07.9 Tricuspid valve disease, unspecified	0.000	0.919	0.081
I07.8 Other tricuspid valve diseases	0.000	0.919	0.081
I07.2 Tricuspid stenosis with insufficiency	0.000	0.919	0.081
I07.0 Tricuspid stenosis	0.000	0.919	0.081
I72 Other aneurysm	0.000	0.920	0.080
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.079	0.920	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.921	0.079
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.921	0.079
I06.8 Other rheumatic aortic valve diseases	0.000	0.921	0.079
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.921	0.079
I06.1 Rheumatic aortic insufficiency	0.000	0.921	0.079
I06.0 Rheumatic aortic stenosis	0.000	0.921	0.079
I74 Arterial embolism and thrombosis	0.000	0.921	0.079
M21.29 Flexion deformity (Site unspecified)	0.078	0.922	0.000
M21.28 Flexion deformity (Other)	0.078	0.922	0.000
M21.26 Flexion deformity (Lower leg)	0.078	0.922	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.078	0.922	0.000
M21.23 Flexion deformity (Forearm)	0.078	0.922	0.000
M21.22 Flexion deformity (Upper arm)	0.078	0.922	0.000
M21.21 Flexion deformity (Shoulder region)	0.078	0.922	0.000
M21.20 Flexion deformity (Multiple sites)	0.078	0.922	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.922	0.077
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.922	0.077
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.922	0.077
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.922	0.077
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.077	0.923	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.075	0.924	0.000
M20.4 Other hammer toe(s) (acquired)	0.075	0.925	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.074	0.926	0.000
M21.27 Flexion deformity (Ankle and foot)	0.074	0.926	0.000
I70 Atherosclerosis	0.000	0.927	0.073
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.927	0.073
I09.8 Other specified rheumatic heart diseases	0.000	0.928	0.072
I09.2 Chronic rheumatic pericarditis	0.000	0.928	0.072
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.928	0.072
I09.0 Rheumatic myocarditis	0.000	0.928	0.072
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.929	0.071
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.929	0.071
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.929	0.071
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.929	0.071
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.929	0.071
C50 Malignant neoplasm of breast	0.070	0.930	0.000
I20.0 Unstable angina	0.000	0.931	0.069
I15.9 Seconday hypertension, unspecified	0.000	0.931	0.069
I15.8 Other secondary hypertension	0.000	0.931	0.069

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations