TreeWAS – Variant ID: rs511154

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I21 Acute myocardial infarction	1.000	0.000	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.999	0.001	0.000
I21.9 Acute myocardial infarction, unspecified	0.997	0.003	0.000
I21.4 Acute subendocardial myocardial infarction	0.980	0.020	0.000
I10 Essential (primary) hypertension	0.963	0.037	0.000
I20 Angina pectoris	0.918	0.082	0.000
I25.5 Ischaemic cardiomyopathy	0.918	0.082	0.000
I25.3 Aneurysm of heart	0.911	0.089	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.891	0.109	0.000
I20.9 Angina pectoris, unspecified	0.871	0.129	0.000
I22 Subsequent myocardial infarction	0.804	0.196	0.000
I24 Other acute ischaemic heart diseases	0.783	0.217	0.000
I20.1 Angina pectoris with documented spasm	0.747	0.253	0.000
I24.8 Other forms of acute ischaemic heart disease	0.743	0.257	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.711	0.289	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.702	0.298	0.000
I23 Certain current complications following acute myocardial infarction	0.700	0.300	0.000
I25.4 Coronary artery aneurysm	0.677	0.323	0.000
I20.0 Unstable angina	0.664	0.336	0.000
I25.6 Silent myocardial ischaemia	0.635	0.364	0.000
I10-I15 Hypertensive diseases	0.610	0.390	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.599	0.401	0.000
I24.1 Dressler's syndrome	0.581	0.419	0.000
I25.2 Old myocardial infarction	0.577	0.423	0.000
Chapter IX Diseases of the circulatory system	0.555	0.445	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.538	0.462	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.529	0.471	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.502	0.498	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.502	0.498	0.000
I22.8 Subsequent myocardial infarction of other sites	0.487	0.513	0.000
I23.8 Other current complications following acute myocardial infarction	0.484	0.515	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.467	0.533	0.000
I13 Hypertensive heart and renal disease	0.428	0.572	0.000
I20.8 Other forms of angina pectoris	0.417	0.583	0.000
I15 Secondary hypertension	0.402	0.598	0.000
I11 Hypertensive heart disease	0.376	0.624	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.369	0.630	0.000
I00-I02 Acute rheumatic fever	0.366	0.634	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.352	0.648	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.320	0.680	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.307	0.693	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.307	0.693	0.000
I15.8 Other secondary hypertension	0.305	0.694	0.000
I15.1 Hypertension secondary to other renal disorders	0.305	0.695	0.000
I05-I09 Chronic rheumatic heart diseases	0.298	0.702	0.000
I15.0 Renovascular hypertension	0.290	0.710	0.000
I26 Pulmonary embolism	0.287	0.713	0.000
I28 Other diseases of pulmonary vessels	0.282	0.718	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.280	0.719	0.000
I15.2 Hypertension secondary to endocrine disorders	0.270	0.730	0.000
I02 Rheumatic chorea	0.263	0.737	0.000
I01 Rheumatic fever with heart involvement	0.263	0.737	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.253	0.747	0.000
I28.8 Other specified diseases of pulmonary vessels	0.240	0.760	0.000
I00 Rheumatic fever without mention of heart involvement	0.231	0.769	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.230	0.769	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.228	0.772	0.000
I30-I52 Other forms of heart disease	0.227	0.773	0.000
I15.9 Seconday hypertension, unspecified	0.222	0.778	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.221	0.778	0.000
I06 Rheumatic aortic valve diseases	0.221	0.779	0.000
I50 Heart failure	0.215	0.785	0.000
I45 Other conduction disorders	0.213	0.787	0.000
I09 Other rheumatic heart diseases	0.209	0.791	0.000
I45.6 Preexcitation syndrome	0.205	0.795	0.000
I28.1 Aneurysm of pulmonary artery	0.202	0.798	0.000
I31 Other diseases of pericardium	0.199	0.801	0.000
I45.3 Trifascicular block	0.198	0.802	0.000
I33 Acute and subacute endocarditis	0.197	0.803	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.197	0.803	0.000
I50.1 Left ventricular failure	0.196	0.804	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.195	0.805	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.194	0.806	0.000
I08 Multiple valve diseases	0.193	0.807	0.000
I07 Rheumatic tricuspid valve diseases	0.192	0.808	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.188	0.811	0.000
I01.8 Other acute rheumatic heart disease	0.188	0.811	0.000
I01.2 Acute rheumatic myocarditis	0.188	0.811	0.000
I01.1 Acute rheumatic endocarditis	0.188	0.811	0.000
I01.0 Acute rheumatic pericarditis	0.188	0.811	0.000
I02.9 Rheumatic chorea without heart involvement	0.188	0.811	0.000
I02.0 Rheumatic chorea with heart involvement	0.188	0.811	0.000
I31.3 Pericardial effusion (noninflammatory)	0.187	0.813	0.000
I47 Paroxysmal tachycardia	0.184	0.816	0.000
I50.0 Congestive heart failure	0.183	0.817	0.000
I36 Nonrheumatic tricuspid valve disorders	0.181	0.819	0.000
I45.4 Nonspecific intraventricular block	0.176	0.824	0.000
I05 Rheumatic mitral valve diseases	0.175	0.825	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.172	0.828	0.000
I08.8 Other multiple valve diseases	0.171	0.829	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.169	0.831	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.169	0.831	0.000
I45.8 Other specified conduction disorders	0.169	0.831	0.000
I30 Acute pericarditis	0.168	0.832	0.000
I06.1 Rheumatic aortic insufficiency	0.166	0.833	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.165	0.835	0.000
I40 Acute myocarditis	0.164	0.836	0.000
I47.2 Ventricular tachycardia	0.164	0.836	0.000
I33.9 Acute endocarditis, unspecified	0.164	0.836	0.000
I52 Other heart disorders in diseases classified elsewhere	0.163	0.837	0.000
I48 Atrial fibrillation and flutter	0.163	0.837	0.000
I41 Myocarditis in diseases classified elsewhere	0.163	0.837	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.163	0.837	0.000
I32 Pericarditis in diseases classified elsewhere	0.163	0.837	0.000
I50.9 Heart failure, unspecified	0.162	0.838	0.000
I33.0 Acute and subacute infective endocarditis	0.159	0.840	0.000
I06.8 Other rheumatic aortic valve diseases	0.159	0.841	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.158	0.842	0.000
I31.0 Chronic adhesive pericarditis	0.158	0.842	0.000
I70 Atherosclerosis	0.158	0.842	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.156	0.844	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.155	0.844	0.000
I12 Hypertensive renal disease	0.155	0.845	0.000
I99 Other and unspecified disorders of circulatory system	0.153	0.847	0.000
I45.0 Right fascicular block	0.152	0.847	0.000
I06.0 Rheumatic aortic stenosis	0.151	0.849	0.000
I09.8 Other specified rheumatic heart diseases	0.150	0.850	0.000
I09.2 Chronic rheumatic pericarditis	0.150	0.850	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.150	0.850	0.000
I09.0 Rheumatic myocarditis	0.150	0.850	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.148	0.852	0.000
I37 Pulmonary valve disorders	0.147	0.853	0.000
I09.9 Rheumatic heart disease, unspecified	0.145	0.854	0.000
I46 Cardiac arrest	0.144	0.856	0.000
I31.8 Other specified diseases of pericardium	0.143	0.857	0.000
I31.2 Haemopericardium, not elsewhere classified	0.143	0.857	0.000
I05.2 Mitral stenosis with insufficiency	0.141	0.859	0.000
I07.9 Tricuspid valve disease, unspecified	0.138	0.862	0.000
I07.8 Other tricuspid valve diseases	0.138	0.862	0.000
I07.2 Tricuspid stenosis with insufficiency	0.138	0.862	0.000
I07.0 Tricuspid stenosis	0.138	0.862	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.136	0.864	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.134	0.866	0.000
I08.9 Multiple valve disease, unspecified	0.134	0.866	0.000
I30.9 Acute pericarditis, unspecified	0.132	0.868	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.132	0.868	0.000
I70.0 Atherosclerosis of aorta	0.132	0.868	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.130	0.870	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.130	0.870	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.130	0.870	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.130	0.870	0.000
I72 Other aneurysm	0.130	0.870	0.000
I47.0 Reentry ventricular arrhythmia	0.129	0.871	0.000
I73 Other peripheral vascular diseases	0.129	0.871	0.000
I45.1 Other and unspecified right bundle-branch block	0.128	0.872	0.000
I05.1 Rheumatic mitral insufficiency	0.128	0.872	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.126	0.874	0.000
I31.1 Chronic constrictive pericarditis	0.126	0.874	0.000
E78.0 Pure hypercholesterolaemia	0.126	0.874	0.000
I30.8 Other forms of acute pericarditis	0.125	0.875	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.124	0.875	0.001
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.124	0.876	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.124	0.876	0.000
I05.8 Other mitral valve diseases	0.123	0.876	0.000
I40.9 Acute myocarditis, unspecified	0.123	0.876	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.121	0.879	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.120	0.880	0.000
I45.5 Other specified heart block	0.120	0.880	0.000
I70.1 Atherosclerosis of renal artery	0.120	0.880	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.119	0.881	0.000
I40.8 Other acute myocarditis	0.118	0.882	0.000
I40.1 Isolated myocarditis	0.118	0.882	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.117	0.883	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.117	0.883	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.117	0.883	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.117	0.883	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.117	0.883	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.117	0.883	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.117	0.883	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.117	0.883	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.117	0.883	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.117	0.883	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.117	0.883	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.117	0.883	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.117	0.883	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.117	0.883	0.000
I48.4 Atypical atrial flutter	0.117	0.883	0.000
I48.3 Typical atrial flutter	0.117	0.883	0.000
I48.2 Chronic atrial fibrillation	0.117	0.883	0.000
I48.1 Persistent atrial fibrillation	0.117	0.883	0.000
I48.0 Paroxysmal atrial fibrillation	0.117	0.883	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.117	0.883	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.117	0.883	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.117	0.883	0.000
I07.1 Tricuspid insufficiency	0.116	0.884	0.000
I05.0 Mitral stenosis	0.115	0.884	0.000
I70.9 Generalised and unspecified atherosclerosis	0.114	0.886	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.114	0.886	0.000
I73.9 Peripheral vascular disease, unspecified	0.113	0.887	0.000
I40.0 Infective myocarditis	0.112	0.888	0.000
I70.8 Atherosclerosis of other arteries	0.112	0.888	0.000
I77 Other disorders of arteries and arterioles	0.110	0.890	0.000
I37.0 Pulmonary valve stenosis	0.110	0.890	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.110	0.890	0.000
I97.1 Other functional disturbances following cardiac surgery	0.110	0.890	0.000
I31.9 Disease of pericardium, unspecified	0.109	0.891	0.000
I46.0 Cardiac arrest with successful resuscitation	0.106	0.894	0.000
I37.9 Pulmonary valve disorder, unspecified	0.105	0.894	0.000
I37.8 Other pulmonary valve disorders	0.105	0.894	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.105	0.894	0.000
I77.1 Stricture of artery	0.104	0.896	0.000
I30.1 Infective pericarditis	0.104	0.896	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.104	0.896	0.000
I72.3 Aneurysm of iliac artery	0.102	0.898	0.000
I73.8 Other specified peripheral vascular diseases	0.100	0.899	0.000
I46.1 Sudden cardiac death, so described	0.099	0.901	0.000
I34 Nonrheumatic mitral valve disorders	0.099	0.901	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.099	0.901	0.000
I72.1 Aneurysm of artery of upper extremity	0.098	0.902	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.096	0.904	0.000
I72.0 Aneurysm of carotid artery	0.096	0.904	0.000
I72.4 Aneurysm of artery of lower extremity	0.096	0.904	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.096	0.904	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.095	0.905	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.093	0.906	0.000
I51 Complications and ill-defined descriptions of heart disease	0.094	0.906	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.093	0.907	0.000
I45.9 Conduction disorder, unspecified	0.091	0.909	0.000
I72.9 Aneurysm of unspecified site	0.091	0.909	0.000
I72.8 Aneurysm of other specified arteries	0.090	0.910	0.000
I97.0 Postcardiotomy syndrome	0.090	0.910	0.000
I72.2 Aneurysm of renal artery	0.090	0.910	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.089	0.910	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.088	0.912	0.000
I77.8 Other specified disorders of arteries and arterioles	0.088	0.912	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.087	0.913	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.086	0.914	0.000
I46.9 Cardiac arrest, unspecified	0.086	0.914	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.085	0.914	0.000
I77.2 Rupture of artery	0.085	0.915	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.082	0.917	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.082	0.918	0.000
I44 Atrioventricular and left bundle-branch block	0.082	0.918	0.000
I37.1 Pulmonary valve insufficiency	0.081	0.919	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.080	0.920	0.000
I77.5 Necrosis of artery	0.079	0.921	0.000
I77.4 Coeliac artery compression syndrome	0.079	0.921	0.000
I77.3 Arterial fibromuscular dysplasia	0.079	0.921	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.079	0.921	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.079	0.921	0.000
I98.0 Cardiovascular syphilis	0.079	0.921	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.079	0.921	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.079	0.921	0.000
I51.9 Heart disease, unspecified	0.078	0.922	0.000
I45.2 Bifascicular block	0.078	0.922	0.001
I44.2 Atrioventricular block, complete	0.077	0.923	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.075	0.925	0.000
I79.1 Aortitis in diseases classified elsewhere	0.075	0.925	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.075	0.925	0.000
I35 Nonrheumatic aortic valve disorders	0.074	0.926	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.073	0.927	0.000
I05.9 Mitral valve disease, unspecified	0.072	0.928	0.000
I78 Diseases of capillaries	0.072	0.928	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.072	0.928	0.000
I51.0 Cardiac septal defect, acquired	0.070	0.930	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.069	0.930	0.000
I74 Arterial embolism and thrombosis	0.069	0.931	0.000
I51.4 Myocarditis, unspecified	0.068	0.932	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.067	0.933	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.067	0.933	0.000
I51.5 Myocardial degeneration	0.067	0.933	0.000
I44.6 Other and unspecified fascicular block	0.066	0.934	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.064	0.936	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.063	0.937	0.000
I77.0 Arteriovenous fistula, acquired	0.062	0.938	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.061	0.939	0.000
I44.5 Left posterior fascicular block	0.059	0.941	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.058	0.941	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.057	0.943	0.000
I51.6 Cardiovascular disease, unspecified	0.057	0.943	0.000
I49 Other cardiac arrhythmias	0.057	0.943	0.000
I35.9 Aortic valve disorder, unspecified	0.056	0.944	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.054	0.946	0.000
I44.4 Left anterior fascicular block	0.053	0.947	0.000
I78.9 Disease of capillaries, unspecified	0.053	0.947	0.000
I44.3 Other and unspecified atrioventricular block	0.052	0.948	0.000
I12.9 Hypertensive renal disease without renal failure	0.049	0.951	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.048	0.952	0.000
I49.1 Atrial premature depolarisation	0.048	0.952	0.000
I49.4 Other and unspecified premature depolarisation	0.048	0.952	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.047	0.953	0.000
N93.8 Other specified abnormal uterine and vaginal bleeding	0.046	0.954	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.045	0.954	0.000
I78.8 Other diseases of capillaries	0.045	0.955	0.000
I38 Endocarditis, valve unspecified	0.045	0.955	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.045	0.955	0.000
I49.5 Sick sinus syndrome	0.044	0.956	0.000
I51.8 Other ill-defined heart diseases	0.044	0.956	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.041	0.959	0.000
I74.8 Embolism and thrombosis of other arteries	0.041	0.959	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.041	0.959	0.000
I49.2 Junctional premature depolarisation	0.041	0.959	0.000
I44.1 Atrioventricular block, second degree	0.040	0.960	0.000
I27 Other pulmonary heart diseases	0.038	0.961	0.001
E78.1 Pure hyperglyceridaemia	0.037	0.963	0.000
I35.8 Other aortic valve disorders	0.037	0.963	0.000
I34.0 Mitral (valve) insufficiency	0.037	0.963	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.036	0.963	0.000
I51.7 Cardiomegaly	0.036	0.964	0.000
E78.2 Mixed hyperlipidaemia	0.035	0.965	0.000
E78.4 Other hyperlipidaemia	0.034	0.965	0.000
I47.1 Supraventricular tachycardia	0.034	0.966	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.032	0.967	0.000
E78.3 Hyperchylomicronaemia	0.032	0.968	0.000
E78.6 Lipoprotein deficiency	0.031	0.969	0.000
I34.1 Mitral (valve) prolapse	0.031	0.969	0.000
E78.5 Hyperlipidaemia, unspecified	0.029	0.971	0.000
I49.0 Ventricular fibrillation and flutter	0.029	0.971	0.000
I27.1 Kyphoscoliotic heart disease	0.028	0.972	0.001
I78.1 Naevus, nonneoplastic	0.028	0.972	0.000
I27.8 Other specified pulmonary heart diseases	0.026	0.973	0.001
E78.8 Other disorders of lipoprotein metabolism	0.026	0.974	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.975	0.025
F31 Bipolar affective disorder	0.000	0.975	0.025
B18 Chronic viral hepatitis	0.000	0.976	0.024
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.976	0.024
B18.2 Chronic viral hepatitis C	0.000	0.976	0.024
I74.5 Embolism and thrombosis of iliac artery	0.023	0.976	0.000
B15-B19 Viral hepatitis	0.000	0.977	0.023
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.977	0.023
I73.0 Raynaud's syndrome	0.023	0.977	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.978	0.022
I08.0 Disorders of both mitral and aortic valves	0.022	0.978	0.001
I44.7 Left bundle-branch block, unspecified	0.022	0.978	0.000
I77.6 Arteritis, unspecified	0.021	0.978	0.001
I71 Aortic aneurysm and dissection	0.022	0.978	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.978	0.022
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.978	0.022
B19 Unspecified viral hepatitis	0.000	0.979	0.021
B17.1 Acute hepatitis C	0.000	0.979	0.021
B17 Other acute viral hepatitis	0.000	0.979	0.021
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.979	0.021
I12.0 Hypertensive renal disease with renal failure	0.021	0.979	0.000
B19.9 Unspecified viral hepatitis without coma	0.000	0.980	0.020
B15 Acute hepatitis A	0.000	0.980	0.020
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.981	0.019
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.981	0.019
B16 Acute hepatitis B	0.000	0.981	0.019
I49.3 Ventricular premature depolarisation	0.019	0.981	0.000
I35.0 Aortic (valve) stenosis	0.019	0.981	0.000
F31.8 Other bipolar affective disorders	0.000	0.982	0.018
M41.9 Scoliosis, unspecified	0.000	0.982	0.018
Z43.2 Attention to ileostomy	0.000	0.982	0.018
B18.9 Chronic viral hepatitis, unspecified	0.000	0.982	0.018
I49.8 Other specified cardiac arrhythmias	0.018	0.982	0.000
B18.8 Other chronic viral hepatitis	0.000	0.982	0.018
B18.0 Chronic viral hepatitis B with delta-agent	0.000	0.982	0.018
M84.1 Nonunion of fracture [pseudarthrosis]	0.018	0.982	0.000
B15.9 Hepatitis A without hepatic coma	0.000	0.982	0.018
I35.1 Aortic (valve) insufficiency	0.017	0.983	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.983	0.017
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.017	0.983	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.017	0.983	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.016	0.983	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.016	0.984	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.984	0.016
Z85.6 Personal history of leukaemia	0.000	0.984	0.016
I71.8 Aortic aneurysm of unspecified site, ruptured	0.016	0.984	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.016	0.984	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.016	0.984	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.016	0.984	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.016	0.984	0.000
I42 Cardiomyopathy	0.016	0.984	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.016	0.984	0.000
B19.0 Unspecified viral hepatitis with coma	0.000	0.984	0.015
F31.7 Bipolar affective disorder, currently in remission	0.000	0.985	0.015
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.000	0.985	0.015
Z74.0 Reduced mobility	0.000	0.985	0.015
B15.0 Hepatitis A with hepatic coma	0.000	0.985	0.014
B17.9 Acute viral hepatitis, unspecified	0.000	0.985	0.014
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.000	0.986	0.014
C85.1 B-cell lymphoma, unspecified	0.000	0.986	0.014
M54.12 Radiculopathy (Cervical region)	0.014	0.986	0.000
I49.9 Cardiac arrhythmia, unspecified	0.014	0.986	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.986	0.014
I27.9 Pulmonary heart disease, unspecified	0.013	0.986	0.001
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.986	0.014
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.000	0.986	0.014
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.000	0.986	0.014
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.000	0.986	0.014
C91.1 Chronic lymphocytic leukaemia	0.000	0.986	0.014
F20.9 Schizophrenia, unspecified	0.000	0.986	0.014
B17.8 Other specified acute viral hepatitis	0.000	0.986	0.014
M54.9 Dorsalgia, unspecified	0.014	0.986	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.014	0.986	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.986	0.014
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.014	0.986	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.014	0.986	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.013	0.986	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.013	0.987	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.987	0.013
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.987	0.013
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.987	0.013
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.987	0.013
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.013	0.987	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.013	0.987	0.000
B17.2 Acute hepatitis E	0.000	0.987	0.013
F20 Schizophrenia	0.000	0.987	0.013
M54.1 Radiculopathy	0.013	0.987	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.012	0.988	0.000
M41 Scoliosis	0.000	0.988	0.012
M54 Dorsalgia	0.012	0.988	0.000
M54.5 Low back pain	0.012	0.988	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.012	0.988	0.000
F20.0 Paranoid schizophrenia	0.000	0.988	0.012
K35 Acute appendicitis	0.012	0.988	0.000
M54.59 Low back pain (Site unspecified)	0.012	0.988	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.012	0.988	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.012	0.988	0.000
Z50.0 Cardiac rehabilitation	0.012	0.988	0.000
F52.2 Failure of genital response	0.011	0.988	0.000
M54.57 Low back pain (Lumbosacral region)	0.011	0.989	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.989	0.011
I42.3 Endomyocardial (eosinophilic) disease	0.011	0.989	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.011	0.989	0.000
I42.5 Other restrictive cardiomyopathy	0.011	0.989	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.000	0.989	0.011
M54.92 Dorsalgia, unspecified (Cervical region)	0.011	0.989	0.000
I60-I69 Cerebrovascular diseases	0.011	0.989	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.989	0.011
I42.4 Endocardial fibroelastosis	0.011	0.989	0.000
F30-F39 Mood [affective] disorders	0.000	0.989	0.011
K35.2 Acute appendicitis with generalized peritonitis	0.011	0.989	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.989	0.011
K35.8 Acute appendicitis, other and unspecified	0.011	0.989	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.011	0.989	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.011	0.989	0.000
M54.19 Radiculopathy (Site unspecified)	0.011	0.989	0.000
I61 Intracerebral haemorrhage	0.011	0.989	0.000
I27.0 Primary pulmonary hypertension	0.010	0.990	0.001
M54.16 Radiculopathy (Lumbar region)	0.010	0.990	0.000
F20.8 Other schizophrenia	0.000	0.990	0.010
H25.9 Senile cataract, unspecified	0.010	0.990	0.000
I42.6 Alcoholic cardiomyopathy	0.010	0.990	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.010	0.990	0.000
I61.8 Other intracerebral haemorrhage	0.010	0.990	0.000
F81 Specific developmental disorders of scholastic skills	0.000	0.990	0.010
I61.5 Intracerebral haemorrhage, intraventricular	0.010	0.990	0.000
F30 Manic episode	0.000	0.990	0.010
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.990	0.010
K38 Other diseases of appendix	0.010	0.990	0.000
I42.8 Other cardiomyopathies	0.009	0.990	0.000
K38.8 Other specified diseases of appendix	0.010	0.990	0.000
M54.52 Low back pain-Cervical	0.009	0.990	0.000
C91 Lymphoid leukaemia	0.000	0.990	0.010
F20.6 Simple schizophrenia	0.000	0.991	0.009
F20.4 Postschizophrenic depression	0.000	0.991	0.009
F20.3 Undifferentiated schizophrenia	0.000	0.991	0.009
F20.1 Hebephrenic schizophrenia	0.000	0.991	0.009
K35-K38 Diseases of appendix	0.009	0.991	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.009	0.991	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.009	0.991	0.000
M41.5 Other secondary scoliosis	0.000	0.991	0.009
M54.14 Radiculopathy (Thoracic region)	0.009	0.991	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.009	0.991	0.000
M41.2 Other idiopathic scoliosis	0.000	0.991	0.009
Z43 Attention to artificial openings	0.000	0.991	0.009
M54.13 Radiculopathy (Cervicothoracic region)	0.009	0.991	0.000
K35.3 Acute appendicitis with localized peritonitis	0.009	0.991	0.000
F80-F89 Disorders of psychological development	0.000	0.991	0.009
M41.3 Thoracogenic scoliosis	0.000	0.991	0.009
M41.1 Juvenile idiopathic scoliosis	0.000	0.991	0.009
M41.0 Infantile idiopathic scoliosis	0.000	0.991	0.009
M54.8 Other dorsalgia	0.009	0.991	0.000
F23 Acute and transient psychotic disorders	0.000	0.991	0.009
M54.2 Cervicalgia	0.009	0.991	0.000
M54.0 Panniculitis affecting regions of neck and back	0.009	0.991	0.000
M54.53 Low back pain-Cervicothoracic	0.009	0.991	0.000
M54.51 Low back pain-Occipit-atl-axl	0.009	0.991	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.991	0.009
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.009	0.991	0.000
F22 Persistent delusional disorders	0.000	0.991	0.009
F52 Sexual dysfunction, not caused by organic disorder or disease	0.007	0.991	0.001
M41.8 Other forms of scoliosis	0.000	0.991	0.009
N87.9 Dysplasia of cervix uteri, unspecified	0.009	0.991	0.000
M41.4 Neuromuscular scoliosis	0.000	0.991	0.008
Z43.1 Attention to gastrostomy	0.000	0.991	0.009
F29 Unspecified nonorganic psychosis	0.000	0.991	0.009
Z74 Problems related to care-provider dependency	0.000	0.991	0.009
M54.10 Radiculopathy (Multiple sites in spine)	0.008	0.991	0.000
F25 Schizoaffective disorders	0.000	0.991	0.008
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.008	0.992	0.000
F30.0 Hypomania	0.000	0.992	0.008
M47.92 Spondylosis, unspecified (Cervical region)	0.008	0.992	0.000
M54.54 Low back pain-Thoracic	0.008	0.992	0.000
F20.2 Catatonic schizophrenia	0.000	0.992	0.008
K36 Other appendicitis	0.008	0.992	0.000
F28 Other nonorganic psychotic disorders	0.000	0.992	0.008
F24 Induced delusional disorder	0.000	0.992	0.008
F21 Schizotypal disorder	0.000	0.992	0.008

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations