TreeWAS – Variant ID: rs3731239

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I20.9 Angina pectoris, unspecified	0.000	0.000	1.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.000	1.000
I25.2 Old myocardial infarction	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.000	1.000
Z95.1 Presence of aortocoronary bypass graft	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I21 Acute myocardial infarction	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.000	1.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I20.0 Unstable angina	0.000	0.000	1.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.000	1.000
I24 Other acute ischaemic heart diseases	0.000	0.003	0.997
Z95.0 Presence of cardiac pacemaker	0.000	0.005	0.995
I24.8 Other forms of acute ischaemic heart disease	0.000	0.006	0.994
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.016	0.984
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.024	0.976
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.046	0.954
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.057	0.943
I20.8 Other forms of angina pectoris	0.000	0.088	0.912
I22 Subsequent myocardial infarction	0.000	0.090	0.910
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.114	0.886
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.114	0.886
C71 Malignant neoplasm of brain	0.877	0.123	0.000
C71.3 Parietal lobe	0.868	0.132	0.000
C71.9 Brain, unspecified	0.857	0.143	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.145	0.855
C71.1 Frontal lobe	0.846	0.154	0.000
I25.3 Aneurysm of heart	0.000	0.160	0.840
Z95.3 Presence of xenogenic heart valve	0.000	0.169	0.831
I25.4 Coronary artery aneurysm	0.000	0.185	0.815
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.194	0.806
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.195	0.805
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.199	0.801
C71.8 Overlapping lesion of brain	0.799	0.201	0.000
C71.0 Cerebrum, except lobes and ventricles	0.789	0.211	0.000
I23 Certain current complications following acute myocardial infarction	0.000	0.239	0.761
C71.4 Occipital lobe	0.742	0.258	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.283	0.717
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
C71.5 Cerebral ventricle	0.696	0.304	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.305	0.695
I24.1 Dressler's syndrome	0.000	0.362	0.638
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.364	0.636
I25.5 Ischaemic cardiomyopathy	0.000	0.367	0.633
C71.6 Cerebellum	0.629	0.371	0.000
C71.7 Brain stem	0.608	0.391	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.407	0.593
I23.8 Other current complications following acute myocardial infarction	0.000	0.410	0.590
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.000	0.417	0.583
I21.4 Acute subendocardial myocardial infarction	0.000	0.437	0.563
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.442	0.558
I74 Arterial embolism and thrombosis	0.000	0.451	0.549
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.454	0.546
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.454	0.546
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.454	0.546
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.454	0.546
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.454	0.546
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.454	0.546
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.454	0.546
C71.2 Temporal lobe	0.535	0.465	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.468	0.532
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.474	0.526
Z82.3 Family history of stroke	0.000	0.492	0.508
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.000	0.493	0.507
I72 Other aneurysm	0.000	0.509	0.491
Chapter IX Diseases of the circulatory system	0.000	0.516	0.484
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.000	0.535	0.465
I73 Other peripheral vascular diseases	0.000	0.537	0.463
I22.8 Subsequent myocardial infarction of other sites	0.000	0.550	0.449
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.553	0.447
I70 Atherosclerosis	0.000	0.556	0.444
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.556	0.444
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.557	0.443
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.557	0.443
I73.9 Peripheral vascular disease, unspecified	0.000	0.558	0.442
I74.5 Embolism and thrombosis of iliac artery	0.000	0.570	0.430
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.576	0.424
I20.1 Angina pectoris with documented spasm	0.000	0.579	0.421
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.000	0.582	0.418
I77 Other disorders of arteries and arterioles	0.000	0.584	0.416
I74.8 Embolism and thrombosis of other arteries	0.000	0.584	0.416
Z82.2 Family history of deafness and hearing loss	0.000	0.587	0.413
I72.0 Aneurysm of carotid artery	0.000	0.588	0.412
I72.8 Aneurysm of other specified arteries	0.000	0.597	0.403
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.606	0.394
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.612	0.388
I70.1 Atherosclerosis of renal artery	0.000	0.615	0.385
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.620	0.380
I72.4 Aneurysm of artery of lower extremity	0.000	0.623	0.377
Z82.1 Family history of blindness and visual loss	0.000	0.625	0.375
I72.9 Aneurysm of unspecified site	0.000	0.626	0.374
I72.2 Aneurysm of renal artery	0.000	0.627	0.373
I77.1 Stricture of artery	0.000	0.639	0.361
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.644	0.356
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.648	0.352
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.648	0.352
I72.1 Aneurysm of artery of upper extremity	0.000	0.648	0.352
I60-I69 Cerebrovascular diseases	0.000	0.649	0.351
I72.3 Aneurysm of iliac artery	0.000	0.654	0.346
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.658	0.342
I77.0 Arteriovenous fistula, acquired	0.000	0.664	0.336
I62 Other nontraumatic intracranial haemorrhage	0.000	0.673	0.326
I70.8 Atherosclerosis of other arteries	0.000	0.677	0.322
Z95.4 Presence of other heart-valve replacement	0.000	0.679	0.321
I00-I02 Acute rheumatic fever	0.000	0.681	0.318
I79.1 Aortitis in diseases classified elsewhere	0.000	0.682	0.318
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.682	0.318
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.686	0.314
I67 Other cerebrovascular diseases	0.000	0.686	0.314
I70.9 Generalised and unspecified atherosclerosis	0.000	0.687	0.313
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.688	0.312
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.690	0.309
I67.1 Cerebral aneurysm, nonruptured	0.000	0.696	0.304
I73.0 Raynaud's syndrome	0.000	0.697	0.303
I60 Subarachnoid haemorrhage	0.000	0.699	0.301
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.700	0.299
I77.5 Necrosis of artery	0.000	0.701	0.298
I77.4 Coeliac artery compression syndrome	0.000	0.701	0.298
I77.3 Arterial fibromuscular dysplasia	0.000	0.701	0.298
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.705	0.294
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.709	0.291
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.717	0.283
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.282	0.718	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.724	0.276
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.726	0.274
I73.8 Other specified peripheral vascular diseases	0.000	0.727	0.273
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.730	0.270
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.735	0.265
I77.2 Rupture of artery	0.000	0.737	0.262
I65.2 Occlusion and stenosis of carotid artery	0.000	0.741	0.259
I70.0 Atherosclerosis of aorta	0.000	0.746	0.254
I62.1 Nontraumatic extradural haemorrhage	0.000	0.747	0.253
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.750	0.250
I10-I15 Hypertensive diseases	0.000	0.754	0.245
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.760	0.240
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.761	0.239
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.763	0.237
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.764	0.235
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.765	0.235
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.768	0.231
I02 Rheumatic chorea	0.000	0.771	0.228
I01 Rheumatic fever with heart involvement	0.000	0.771	0.228
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.775	0.225
I67.5 Moyamoya disease	0.000	0.775	0.225
I67.4 Hypertensive encephalopathy	0.000	0.775	0.225
I67.3 Progressive vascular leukoencephalopathy	0.000	0.775	0.225
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.776	0.224
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.777	0.223
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.778	0.221
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.780	0.220
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.780	0.220
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.781	0.219
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.784	0.216
I67.9 Cerebrovascular disease, unspecified	0.000	0.785	0.215
I11 Hypertensive heart disease	0.000	0.790	0.210
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.791	0.209
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.792	0.208
Z95.2 Presence of prosthetic heart valve	0.000	0.794	0.206
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.795	0.205
D33.3 Cranial nerves	0.202	0.798	0.000
I65.1 Occlusion and stenosis of basilar artery	0.000	0.798	0.202
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.800	0.200
I00 Rheumatic fever without mention of heart involvement	0.000	0.800	0.200
I67.2 Cerebral atherosclerosis	0.000	0.802	0.198
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.197	0.803	0.000
I15 Secondary hypertension	0.000	0.803	0.197
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.803	0.197
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.803	0.197
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.803	0.197
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.809	0.191
I69 Sequelae of cerebrovascular disease	0.000	0.809	0.191
C69 Malignant neoplasm of eye and adnexa	0.190	0.810	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.811	0.189
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.814	0.186
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.817	0.182
C70 Malignant neoplasm of meninges	0.179	0.821	0.000
I13 Hypertensive heart and renal disease	0.000	0.824	0.176
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.828	0.172
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.828	0.172
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.828	0.172
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.829	0.171
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.830	0.170
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.835	0.165
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.836	0.164
I01.8 Other acute rheumatic heart disease	0.000	0.836	0.164
I01.2 Acute rheumatic myocarditis	0.000	0.836	0.164
I01.1 Acute rheumatic endocarditis	0.000	0.836	0.164
I01.0 Acute rheumatic pericarditis	0.000	0.836	0.164
I02.9 Rheumatic chorea without heart involvement	0.000	0.836	0.164
I02.0 Rheumatic chorea with heart involvement	0.000	0.836	0.164
I15.1 Hypertension secondary to other renal disorders	0.000	0.839	0.161
I68.0 Cerebral amyloid angiopathy	0.000	0.840	0.160
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.843	0.157
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.845	0.154
C69.0 Conjunctiva	0.153	0.846	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.848	0.152
I05-I09 Chronic rheumatic heart diseases	0.000	0.850	0.150
I15.9 Seconday hypertension, unspecified	0.000	0.850	0.150
I60.8 Other subarachnoid haemorrhage	0.000	0.851	0.149
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.001	0.854	0.145
I69.3 Sequelae of cerebral infarction	0.000	0.855	0.145
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.858	0.142
C72.9 Central nervous system, unspecified	0.141	0.858	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.141	0.858	0.000
C72.5 Other and unspecified cranial nerves	0.141	0.858	0.000
C72.4 Acoustic nerve	0.141	0.858	0.000
C72.3 Optic nerve	0.141	0.858	0.000
C72.2 Olfactory nerve	0.141	0.858	0.000
C72.1 Cauda equina	0.141	0.858	0.000
I15.8 Other secondary hypertension	0.000	0.858	0.141
I15.2 Hypertension secondary to endocrine disorders	0.000	0.858	0.141
C69.6 Orbit	0.137	0.862	0.000
C69.8 Overlapping lesion of eye and adnexa	0.136	0.863	0.000
C69.5 Lachrymal gland and duct	0.136	0.863	0.000
C69.4 Ciliary body	0.136	0.863	0.000
C69.2 Retina	0.136	0.863	0.000
C69.1 Cornea	0.136	0.863	0.000
C72.0 Spinal cord	0.136	0.864	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.864	0.136
I15.0 Renovascular hypertension	0.000	0.866	0.134
C69.9 Eye, unspecified	0.132	0.867	0.000
I77.8 Other specified disorders of arteries and arterioles	0.001	0.870	0.129
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.870	0.130
I78 Diseases of capillaries	0.000	0.871	0.128
C70.9 Meninges, unspecified	0.128	0.871	0.000
C70.1 Spinal meninges	0.128	0.871	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.872	0.128
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.873	0.126
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.873	0.126
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.873	0.126
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.873	0.126
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.874	0.126
I09 Other rheumatic heart diseases	0.000	0.877	0.123
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.881	0.118
I71 Aortic aneurysm and dissection	0.000	0.890	0.110
I12 Hypertensive renal disease	0.000	0.890	0.110
I28 Other diseases of pulmonary vessels	0.001	0.893	0.106
C70.0 Cerebral meninges	0.105	0.895	0.000
I09.9 Rheumatic heart disease, unspecified	0.000	0.897	0.103
I07 Rheumatic tricuspid valve diseases	0.000	0.897	0.103
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.897	0.103
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.898	0.102
C69.3 Choroid	0.099	0.901	0.000
I99 Other and unspecified disorders of circulatory system	0.000	0.902	0.098
I78.9 Disease of capillaries, unspecified	0.000	0.907	0.092
I09.8 Other specified rheumatic heart diseases	0.000	0.912	0.088
I09.2 Chronic rheumatic pericarditis	0.000	0.912	0.088
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.912	0.088
I09.0 Rheumatic myocarditis	0.000	0.912	0.088
D33 Benign neoplasm of brain and other parts of central nervous system	0.088	0.912	0.000
I06 Rheumatic aortic valve diseases	0.000	0.914	0.086
I78.8 Other diseases of capillaries	0.000	0.914	0.085
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.917	0.083
I77.6 Arteritis, unspecified	0.001	0.919	0.080
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.921	0.079
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.921	0.079
I28.8 Other specified diseases of pulmonary vessels	0.001	0.921	0.078
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.922	0.078
I28.9 Disease of pulmonary vessels, unspecified	0.001	0.923	0.076
I28.1 Aneurysm of pulmonary artery	0.001	0.923	0.076
I28.0 Arteriovenous fistula of pulmonary vessels	0.001	0.923	0.076
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.925	0.075
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.925	0.075
I07.9 Tricuspid valve disease, unspecified	0.000	0.926	0.074
I07.8 Other tricuspid valve diseases	0.000	0.926	0.074
I07.2 Tricuspid stenosis with insufficiency	0.000	0.926	0.074
I07.0 Tricuspid stenosis	0.000	0.926	0.074
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.927	0.073
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.927	0.073
I98.0 Cardiovascular syphilis	0.000	0.927	0.073
I12.9 Hypertensive renal disease without renal failure	0.000	0.927	0.073
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.928	0.072
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.928	0.072
I07.1 Tricuspid insufficiency	0.000	0.931	0.069
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.934	0.066
I26 Pulmonary embolism	0.001	0.934	0.066
D33.2 Brain, unspecified	0.066	0.934	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.935	0.065
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.936	0.064
D33.4 Spinal cord	0.064	0.936	0.000
D33.9 Central nervous system, unspecified	0.063	0.937	0.000
D33.7 Other specified parts of central nervous system	0.063	0.937	0.000
D33.1 Brain, infratentorial	0.063	0.937	0.000
I06.8 Other rheumatic aortic valve diseases	0.000	0.938	0.062
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.938	0.062
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.939	0.061
I95 Hypotension	0.000	0.939	0.061
D33.0 Brain, supratentorial	0.059	0.940	0.000
I05 Rheumatic mitral valve diseases	0.000	0.944	0.055
L91.0 Keloid scar	0.055	0.945	0.000
C15.5 Lower third of oesophagus	0.055	0.945	0.000
I06.0 Rheumatic aortic stenosis	0.000	0.946	0.054
I97.1 Other functional disturbances following cardiac surgery	0.000	0.946	0.054
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.946	0.054
I95.0 Idiopathic hypotension	0.000	0.946	0.054
I08 Multiple valve diseases	0.000	0.947	0.053
I06.1 Rheumatic aortic insufficiency	0.000	0.947	0.052
I97.0 Postcardiotomy syndrome	0.000	0.949	0.050
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.950	0.050
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.951	0.049
I78.0 Hereditary haemorrhagic telangiectasia	0.001	0.952	0.047
C15 Malignant neoplasm of oesophagus	0.047	0.953	0.000
C15.9 Oesophagus, unspecified	0.046	0.954	0.000
I71.0 Dissection of aorta [any part]	0.000	0.957	0.043
I95.2 Hypotension due to drugs	0.000	0.958	0.042
I95.8 Other hypotension	0.000	0.960	0.040
I05.8 Other mitral valve diseases	0.000	0.960	0.040
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.960	0.040
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.962	0.038
I63 Cerebral infarction	0.000	0.962	0.038
I08.0 Disorders of both mitral and aortic valves	0.000	0.962	0.038
L91 Hypertrophic disorders of skin	0.037	0.963	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.964	0.035
I08.9 Multiple valve disease, unspecified	0.000	0.964	0.035
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.965	0.035
I05.0 Mitral stenosis	0.000	0.965	0.035
I05.2 Mitral stenosis with insufficiency	0.000	0.965	0.035
C15.8 Overlapping lesion of oesophagus	0.034	0.966	0.000
C15.2 Abdominal part of oesophagus	0.034	0.966	0.000
C15.1 Thoracic part of oesophagus	0.034	0.966	0.000
C15.0 Cervical part of oesophagus	0.034	0.966	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.966	0.034
L91.8 Other hypertrophic disorders of skin	0.034	0.966	0.000
C16.0 Cardia	0.031	0.969	0.000
C15.4 Middle third of oesophagus	0.031	0.969	0.000
C15.3 Upper third of oesophagus	0.031	0.969	0.000
I61 Intracerebral haemorrhage	0.000	0.969	0.031
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.970	0.030
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.971	0.029
I12.0 Hypertensive renal disease with renal failure	0.000	0.972	0.028
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.972	0.027
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.972	0.027
I08.8 Other multiple valve diseases	0.000	0.972	0.027
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.973	0.027
L91.9 Hypertrophic disorder of skin, unspecified	0.027	0.973	0.000
C16 Malignant neoplasm of stomach	0.026	0.974	0.000
I95.1 Orthostatic hypotension	0.000	0.974	0.026
C15-C26 Malignant neoplasms of digestive organs	0.025	0.975	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.975	0.025
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.976	0.024
H40.1 Primary open-angle glaucoma	0.000	0.976	0.024
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.978	0.021
C25 Malignant neoplasm of pancreas	0.022	0.978	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.979	0.021
C19 Malignant neoplasm of rectosigmoid junction	0.021	0.979	0.000
C16.8 Overlapping lesion of stomach	0.021	0.979	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.980	0.020
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.980	0.020
C25.1 Body of pancreas	0.020	0.980	0.000
C16.5 Lesser curvature of stomach, unspecified	0.020	0.980	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.980	0.019
E11.5 With peripheral circulatory complications	0.000	0.980	0.020
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.019	0.981	0.000
C16.9 Stomach, unspecified	0.019	0.981	0.000
C16.4 Pylorus	0.019	0.981	0.000
C25.7 Other parts of pancreas	0.019	0.981	0.000
I78.1 Naevus, nonneoplastic	0.000	0.981	0.019
E11.6 With other specified complications	0.000	0.981	0.019
C16.6 Greater curvature of stomach, unspecified	0.018	0.981	0.000
I61.8 Other intracerebral haemorrhage	0.000	0.981	0.018
C25.9 Pancreas, unspecified	0.018	0.982	0.000
C16.1 Fundus of stomach	0.018	0.982	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.982	0.018
C23 Malignant neoplasm of gallbladder	0.017	0.982	0.000
H40 Glaucoma	0.000	0.983	0.017
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.983	0.017
H40.9 Glaucoma, unspecified	0.000	0.983	0.017
E11.1 With ketoacidosis	0.000	0.983	0.017
I61.4 Intracerebral haemorrhage in cerebellum	0.001	0.984	0.016
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.016	0.984	0.000
I27 Other pulmonary heart diseases	0.004	0.984	0.013
C16.2 Body of stomach	0.016	0.984	0.000
C25.8 Overlapping lesion of pancreas	0.016	0.984	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.016	0.984	0.000
C24.9 Biliary tract, unspecified	0.016	0.984	0.000
C25.4 Endocrine pancreas	0.015	0.984	0.000
I63.8 Other cerebral infarction	0.000	0.985	0.015
C24.0 Extrahepatic bile duct	0.015	0.985	0.000
Chapter II Neoplasms	0.015	0.985	0.000
H40.3 Glaucoma secondary to eye trauma	0.000	0.986	0.014
C24.8 Overlapping lesion of biliary tract	0.014	0.986	0.000
C21 Malignant neoplasm of anus and anal canal	0.014	0.986	0.000
C25.0 Head of pancreas	0.014	0.986	0.000
N80.3 Endometriosis of pelvic peritoneum	0.014	0.986	0.000
E11.9 Without complications	0.000	0.986	0.014
E11.4 With neurological complications	0.000	0.987	0.013
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.987	0.013
D00-D09 In situ neoplasms	0.013	0.987	0.000
E11.7 With multiple complications	0.000	0.987	0.013
E11.0 With coma	0.000	0.987	0.013
H40.0 Glaucoma suspect	0.000	0.987	0.013
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.001	0.987	0.012
C24.1 Ampulla of Vater	0.013	0.987	0.000
C16.3 Pyloric antrum	0.012	0.987	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.013	0.987	0.000
C25.3 Pancreatic duct	0.012	0.988	0.000
H40.2 Primary angle-closure glaucoma	0.000	0.988	0.012
C22.9 Liver, unspecified	0.012	0.988	0.000
C48.0 Retroperitoneum	0.012	0.988	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.012	0.988	0.000
D09 Carcinoma in situ of other and unspecified sites	0.012	0.988	0.000
C22.1 Intrahepatic bile duct carcinoma	0.012	0.988	0.000
H40.4 Glaucoma secondary to eye inflammation	0.000	0.988	0.012
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.012	0.988	0.000
D05 Carcinoma in situ of breast	0.012	0.988	0.000
C22.7 Other specified carcinomas of liver	0.012	0.988	0.000
C22.4 Other sarcomas of liver	0.012	0.988	0.000
C22.3 Angiosarcoma of liver	0.012	0.988	0.000
C22.2 Hepatoblastoma	0.012	0.988	0.000
I27.1 Kyphoscoliotic heart disease	0.003	0.988	0.009
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.012	0.988	0.000
E11.8 With unspecified complications	0.000	0.988	0.012
C40-C41 Malignant neoplasms of bone and articular cartilage	0.012	0.988	0.000
D09.0 Bladder	0.012	0.988	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.012	0.988	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.012	0.988	0.000
C20 Malignant neoplasm of rectum	0.012	0.988	0.000
Z71.8 Other specified counselling	0.000	0.989	0.011
H40.6 Glaucoma secondary to drugs	0.000	0.989	0.011
C38 Malignant neoplasm of heart, mediastinum and pleura	0.011	0.989	0.000
D05.1 Intraductal carcinoma in situ	0.011	0.989	0.000
C25.2 Tail of pancreas	0.011	0.989	0.000
H40.8 Other glaucoma	0.000	0.989	0.011
C30 Malignant neoplasm of nasal cavity and middle ear	0.011	0.989	0.000
D02.0 Larynx	0.011	0.989	0.000
E11.2 With renal complications	0.000	0.989	0.011
C05 Malignant neoplasm of palate	0.011	0.989	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.011	0.989	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.011	0.989	0.000
C44 Other malignant neoplasms of skin	0.011	0.989	0.000
D03 Melanoma in situ	0.010	0.990	0.000
C21.2 Cloacogenic zone	0.010	0.990	0.000
C38.4 Pleura	0.010	0.990	0.000
C44.1 Skin of eyelid, including canthus	0.010	0.990	0.000
C44.5 Skin of trunk	0.010	0.990	0.000
D05.7 Other carcinoma in situ of breast	0.010	0.990	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.010	0.990	0.000
H40.5 Glaucoma secondary to other eye disorders	0.000	0.990	0.010
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.010	0.990	0.000
C30.0 Nasal cavity	0.010	0.990	0.000
C05.1 Soft palate	0.010	0.990	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.010	0.990	0.000
C37 Malignant neoplasm of thymus	0.010	0.990	0.000
D09.9 Carcinoma in situ, unspecified	0.010	0.990	0.000
C44.3 Skin of other and unspecified parts of face	0.010	0.990	0.000
C00 Malignant neoplasm of lip	0.010	0.990	0.000
C08.9 Major salivary gland, unspecified	0.010	0.990	0.000
C48.1 Specified parts of peritoneum	0.010	0.990	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.010	0.990	0.000
C33 Malignant neoplasm of trachea	0.010	0.990	0.000
I27.8 Other specified pulmonary heart diseases	0.003	0.990	0.006
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.009	0.990	0.000
C31 Malignant neoplasm of accessory sinuses	0.009	0.990	0.000
C17 Malignant neoplasm of small intestine	0.009	0.991	0.000
C03 Malignant neoplasm of gum	0.009	0.991	0.000
C01 Malignant neoplasm of base of tongue	0.009	0.991	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.009	0.991	0.000
D05.0 Lobular carcinoma in situ	0.009	0.991	0.000
C46 Kaposi's sarcoma	0.009	0.991	0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs	0.009	0.991	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.009	0.991	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.009	0.991	0.000
D02.2 Bronchus and lung	0.009	0.991	0.000
D09.7 Carcinoma in situ of other specified sites	0.009	0.991	0.000
D09.3 Thyroid and other endocrine glands	0.009	0.991	0.000
D09.2 Eye	0.009	0.991	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.009	0.991	0.000
C49.0 Connective and soft tissue of head, face and neck	0.009	0.991	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.009	0.991	0.000
C22.0 Liver cell carcinoma	0.009	0.991	0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.009	0.991	0.000
C11 Malignant neoplasm of nasopharynx	0.009	0.991	0.000
I27.9 Pulmonary heart disease, unspecified	0.003	0.991	0.006
C44.2 Skin of ear and external auricular canal	0.009	0.991	0.000
C10 Malignant neoplasm of oropharynx	0.009	0.991	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.009	0.991	0.000
C44.4 Skin of scalp and neck	0.009	0.991	0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)	0.009	0.991	0.000
D02.4 Respiratory system, unspecified	0.009	0.991	0.000
D02.3 Other parts of respiratory system	0.009	0.991	0.000
D02.1 Trachea	0.009	0.991	0.000
C21.1 Anal canal	0.008	0.991	0.000
C32 Malignant neoplasm of larynx	0.009	0.991	0.000
D36 Benign neoplasm of other and unspecified sites	0.008	0.992	0.000
C13 Malignant neoplasm of hypopharynx	0.008	0.992	0.000
C21.0 Anus, unspecified	0.008	0.992	0.000
D06 Carcinoma in situ of cervix uteri	0.008	0.992	0.000
C05.9 Palate, unspecified	0.008	0.992	0.000
C38.3 Mediastinum, part unspecified	0.008	0.992	0.000
C08.0 Submandibular gland	0.008	0.992	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.008	0.992	0.000
C38.2 Posterior mediastinum	0.008	0.992	0.000
C38.1 Anterior mediastinum	0.008	0.992	0.000
C38.0 Heart	0.008	0.992	0.000
D03.4 Melanoma in situ of scalp and neck	0.008	0.992	0.000
D03.8 Melanoma in situ of other sites	0.008	0.992	0.000
C41.4 Pelvic bones, sacrum and coccyx	0.008	0.992	0.000
C06.0 Cheek mucosa	0.008	0.992	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations