TreeWAS – Variant ID: rs41289512

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
F00-F09 Organic, including symptomatic, mental disorders	1.000	0.000	0.000
I20 Angina pectoris	1.000	0.000	0.000
I25.9 Chronic ischaemic heart disease, unspecified	1.000	0.000	0.000
I21 Acute myocardial infarction	0.999	0.001	0.000
F03 Unspecified dementia	0.999	0.001	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.999	0.001	0.000
Chapter V Mental and behavioural disorders	0.999	0.001	0.000
# Top node	0.999	0.001	0.000
I20.9 Angina pectoris, unspecified	0.998	0.002	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.998	0.002	0.000
G30.9 Alzheimer's disease, unspecified	0.997	0.003	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.997	0.003	0.000
G30 Alzheimer's disease	0.997	0.003	0.000
G30-G32 Other degenerative diseases of the nervous system	0.997	0.003	0.000
R07 Pain in throat and chest	0.996	0.004	0.000
Chapter VI Diseases of the nervous system	0.996	0.004	0.000
Chapter IX Diseases of the circulatory system	0.996	0.004	0.000
R07.4 Chest pain, unspecified	0.996	0.004	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.996	0.004	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.996	0.004	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.995	0.005	0.000
I20.0 Unstable angina	0.995	0.005	0.000
R41.0 Disorientation, unspecified	0.994	0.006	0.000
F00 Dementia in Alzheimer's disease	0.992	0.008	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.991	0.009	0.000
Z95.1 Presence of aortocoronary bypass graft	0.990	0.010	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.987	0.013	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.983	0.017	0.000
R07.2 Precordial pain	0.983	0.017	0.000
E70-E90 Metabolic disorders	0.982	0.017	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.973	0.027	0.000
I25.2 Old myocardial infarction	0.969	0.031	0.000
I21.4 Acute subendocardial myocardial infarction	0.966	0.034	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.963	0.037	0.000
I22 Subsequent myocardial infarction	0.963	0.037	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.953	0.047	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.949	0.051	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.940	0.060	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.940	0.060	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.924	0.076	0.000
E78.2 Mixed hyperlipidaemia	0.922	0.078	0.000
E78.5 Hyperlipidaemia, unspecified	0.922	0.078	0.000
R29.6 Tendency to fall, not elsewhere classified	0.913	0.087	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.911	0.089	0.000
G40-G47 Episodic and paroxysmal disorders	0.908	0.092	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.891	0.109	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.888	0.112	0.000
R41.3 Other amnesia	0.885	0.115	0.000
F01 Vascular dementia	0.884	0.116	0.000
F05.9 Delirium, unspecified	0.877	0.123	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.868	0.132	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.863	0.137	0.000
R00 Abnormalities of heart beat	0.862	0.138	0.001
R44 Other symptoms and signs involving general sensations and perceptions	0.857	0.143	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.849	0.151	0.000
Chapter VII Diseases of the eye and adnexa	0.847	0.153	0.000
R04 Haemorrhage from respiratory passages	0.847	0.153	0.000
I21.9 Acute myocardial infarction, unspecified	0.844	0.156	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.839	0.161	0.000
E50-E64 Other nutritional deficiencies	0.839	0.161	0.000
Z95.0 Presence of cardiac pacemaker	0.838	0.162	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.838	0.162	0.000
R00.1 Bradycardia, unspecified	0.829	0.171	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.829	0.171	0.000
I24 Other acute ischaemic heart diseases	0.816	0.184	0.000
I23 Certain current complications following acute myocardial infarction	0.811	0.189	0.000
H53-H54 Visual disturbances and blindness	0.804	0.196	0.000
H25-H28 Disorders of lens	0.802	0.198	0.000
F01.9 Vascular dementia, unspecified	0.801	0.199	0.000
H54 Blindness and low vision	0.793	0.207	0.000
E78.8 Other disorders of lipoprotein metabolism	0.793	0.207	0.000
F99-F99 Unspecified mental disorder	0.791	0.209	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.791	0.209	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.787	0.213	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.780	0.220	0.000
R44.1 Visual hallucinations	0.767	0.233	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.765	0.235	0.000
G30.0 Alzheimer's disease with early onset	0.764	0.236	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.763	0.237	0.000
E78.1 Pure hyperglyceridaemia	0.762	0.238	0.000
H54.0 Blindness, both eyes	0.761	0.239	0.000
Q60-Q64 Congenital malformations of the urinary system	0.759	0.241	0.000
I20.1 Angina pectoris with documented spasm	0.758	0.242	0.000
F05.8 Other delirium	0.756	0.244	0.000
G70-G73 Diseases of myoneural junction and muscle	0.750	0.250	0.000
Q00-Q07 Congenital malformations of the nervous system	0.749	0.251	0.000
H54.7 Unspecified visual loss	0.739	0.261	0.000
R45 Symptoms and signs involving emotional state	0.734	0.266	0.000
G41 Status epilepticus	0.733	0.267	0.000
G40 Epilepsy	0.732	0.268	0.000
H25 Senile cataract	0.731	0.269	0.000
E61 Deficiency of other nutrient elements	0.728	0.272	0.000
R07.1 Chest pain on breathing	0.724	0.276	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.723	0.277	0.000
G44 Other headache syndromes	0.722	0.278	0.000
F06.7 Mild cognitive disorder	0.722	0.278	0.000
E20-E35 Disorders of other endocrine glands	0.720	0.280	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
I25.4 Coronary artery aneurysm	0.717	0.283	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.717	0.283	0.000
F02 Dementia in other diseases classified elsewhere	0.717	0.283	0.000
F09 Unspecified organic or symptomatic mental disorder	0.717	0.283	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.717	0.283	0.000
F30-F39 Mood [affective] disorders	0.717	0.283	0.000
I60-I69 Cerebrovascular diseases	0.717	0.283	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.716	0.283	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.716	0.283	0.000
E78.6 Lipoprotein deficiency	0.716	0.284	0.000
E78.3 Hyperchylomicronaemia	0.716	0.284	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.716	0.284	0.000
F70-F79 Mental retardation	0.716	0.284	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.716	0.284	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.715	0.285	0.000
G30.8 Other Alzheimer's disease	0.715	0.285	0.000
G30.1 Alzheimer's disease with late onset	0.715	0.285	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.714	0.285	0.000
I00-I02 Acute rheumatic fever	0.714	0.286	0.000
R41.1 Anterograde amnesia	0.714	0.286	0.000
E78.4 Other hyperlipidaemia	0.714	0.286	0.000
R43 Disturbances of smell and taste	0.714	0.286	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.711	0.288	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.711	0.288	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.711	0.288	0.000
L20-L30 Dermatitis and eczema	0.710	0.290	0.000
R04.2 Haemoptysis	0.706	0.294	0.000
E85 Amyloidosis	0.704	0.295	0.000
E84 Cystic fibrosis	0.704	0.295	0.000
E79 Disorders of purine and pyrimidine metabolism	0.704	0.295	0.000
E77 Disorders of glycoprotein metabolism	0.704	0.295	0.000
E76 Disorders of glycosaminoglycan metabolism	0.704	0.295	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.704	0.295	0.000
E74 Other disorders of carbohydrate metabolism	0.704	0.295	0.000
E73 Lactose intolerance	0.704	0.295	0.000
E72 Other disorders of amino-acid metabolism	0.704	0.295	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.704	0.295	0.000
E70 Disorders of aromatic amino-acid metabolism	0.704	0.295	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.704	0.295	0.000
Chapter XXII Codes for special purposes	0.704	0.296	0.000
H10-H13 Disorders of conjunctiva	0.701	0.299	0.000
R46 Symptoms and signs involving appearance and behaviour	0.700	0.300	0.000
L60-L75 Disorders of skin appendages	0.697	0.303	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.695	0.305	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.694	0.305	0.000
G31.8 Other specified degenerative diseases of nervous system	0.692	0.308	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.692	0.308	0.000
I24.8 Other forms of acute ischaemic heart disease	0.691	0.309	0.000
I22.8 Subsequent myocardial infarction of other sites	0.690	0.310	0.000
G45.3 Amaurosis fugax	0.686	0.314	0.000
R01 Cardiac murmurs and other cardiac sounds	0.685	0.315	0.000
H27 Other disorders of lens	0.685	0.315	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.683	0.317	0.000
R41.2 Retrograde amnesia	0.682	0.318	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.680	0.320	0.000
I25.3 Aneurysm of heart	0.678	0.322	0.000
I95 Hypotension	0.676	0.324	0.000
Q61 Cystic kidney disease	0.676	0.324	0.000
I23.8 Other current complications following acute myocardial infarction	0.676	0.324	0.000
F60-F69 Disorders of adult personality and behaviour	0.675	0.325	0.000
R27 Other lack of coordination	0.675	0.325	0.000
F05.1 Delirium superimposed on dementia	0.674	0.326	0.000
F05.0 Delirium not superimposed on dementia, so described	0.674	0.326	0.000
G31.2 Degeneration of nervous system due to alcohol	0.671	0.329	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.670	0.330	0.000
I67 Other cerebrovascular diseases	0.667	0.333	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.667	0.333	0.000
R04.0 Epistaxis	0.667	0.333	0.000
E40-E46 Malnutrition	0.664	0.335	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.664	0.336	0.000
R29.4 Clicking hip	0.663	0.337	0.000
R29.3 Abnormal posture	0.663	0.337	0.000
R29.2 Abnormal reflex	0.663	0.337	0.000
R29.1 Meningismus	0.663	0.337	0.000
R29.0 Tetany	0.663	0.337	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.662	0.338	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.661	0.339	0.000
H25.0 Senile incipient cataract	0.658	0.342	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.655	0.345	0.000
E55 Vitamin D deficiency	0.652	0.348	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.651	0.349	0.000
F80-F89 Disorders of psychological development	0.649	0.350	0.000
E61.1 Iron deficiency	0.650	0.350	0.000
L72 Follicular cysts of skin and subcutaneous tissue	0.646	0.354	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.645	0.355	0.000
L27 Dermatitis due to substances taken internally	0.645	0.355	0.000
F99 Mental disorder, not otherwise specified	0.643	0.357	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.642	0.357	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.642	0.358	0.000
H55-H59 Other disorders of eye and adnexa	0.641	0.359	0.000
H25.8 Other senile cataract	0.639	0.361	0.000
F23 Acute and transient psychotic disorders	0.638	0.362	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.638	0.362	0.000
L72.1 Trichilemmal cyst	0.637	0.363	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.637	0.363	0.000
Q35-Q37 Cleft lip and cleft palate	0.637	0.363	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.637	0.363	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.636	0.364	0.000
R00.2 Palpitations	0.635	0.365	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.635	0.365	0.000
F01.8 Other vascular dementia	0.634	0.366	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.634	0.366	0.000
F01.2 Subcortical vascular dementia	0.634	0.366	0.000
F01.1 Multi-infarct dementia	0.634	0.366	0.000
F01.0 Vascular dementia of acute onset	0.634	0.366	0.000
G44.0 Cluster headache syndrome	0.634	0.366	0.000
I67.8 Other specified cerebrovascular diseases	0.631	0.369	0.000
F29 Unspecified nonorganic psychosis	0.631	0.369	0.000
R02 Gangrene, not elsewhere classified	0.626	0.374	0.000
Chapter VIII Diseases of the ear and mastoid process	0.626	0.374	0.000
Q05 Spina bifida	0.626	0.374	0.000
R00.8 Other and unspecified abnormalities of heart beat	0.625	0.375	0.000
I61 Intracerebral haemorrhage	0.624	0.376	0.000
H10 Conjunctivitis	0.621	0.379	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.619	0.381	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.618	0.381	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.618	0.381	0.000
G45.0 Vertebro-basilar artery syndrome	0.618	0.381	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.617	0.382	0.000
R44.2 Other hallucinations	0.615	0.385	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.611	0.389	0.000
Q80-Q89 Other congenital malformations	0.611	0.389	0.000
L60 Nail disorders	0.611	0.389	0.000
G41.0 Grand mal status epilepticus	0.610	0.390	0.000
R04.9 Haemorrhage from respiratory passages, unspecified	0.607	0.392	0.000
R04.8 Haemorrhage from other sites in respiratory passages	0.607	0.392	0.000
R04.1 Haemorrhage from throat	0.607	0.392	0.000
I95.9 Hypotension, unspecified	0.605	0.395	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.604	0.396	0.000
Q61.2 Polycystic kidney, adult type	0.602	0.398	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.602	0.398	0.000
G31.0 Circumscribed brain atrophy	0.602	0.398	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.601	0.399	0.000
E63 Other nutritional deficiencies	0.601	0.399	0.000
E56 Other vitamin deficiencies	0.601	0.399	0.000
E51 Thiamine deficiency	0.601	0.399	0.000
E50 Vitamin A deficiency	0.601	0.399	0.000
E60 Dietary zinc deficiency	0.601	0.399	0.000
E59 Dietary selenium deficiency	0.601	0.399	0.000
E58 Dietary calcium deficiency	0.601	0.399	0.000
E54 Ascorbic acid deficiency	0.601	0.399	0.000
E52 Niacin deficiency [pellagra]	0.601	0.399	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.601	0.399	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.601	0.399	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.601	0.399	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.601	0.399	0.000
F06.5 Organic dissociative disorder	0.601	0.399	0.000
F06.4 Organic anxiety disorder	0.601	0.399	0.000
F06.3 Organic mood [affective] disorders	0.601	0.399	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.601	0.399	0.000
F06.1 Organic catatonic disorder	0.601	0.399	0.000
F06.0 Organic hallucinosis	0.601	0.399	0.000
I69 Sequelae of cerebrovascular disease	0.599	0.401	0.000
H26 Other cataract	0.598	0.402	0.000
Z95.3 Presence of xenogenic heart valve	0.598	0.402	0.000
Z95.2 Presence of prosthetic heart valve	0.597	0.403	0.000
G20-G26 Extrapyramidal and movement disorders	0.597	0.403	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.596	0.404	0.000
L28 Lichen simplex chronicus and prurigo	0.596	0.404	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.596	0.404	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.596	0.404	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.595	0.405	0.000
R05 Cough	0.594	0.406	0.000
H54.9 Unspecified visual impairment (binocular)	0.591	0.409	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.590	0.410	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.585	0.414	0.000
I24.1 Dressler's syndrome	0.585	0.415	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.582	0.418	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.582	0.418	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.582	0.418	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.582	0.418	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.582	0.418	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.582	0.418	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.582	0.418	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.581	0.419	0.000
R23 Other skin changes	0.581	0.419	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.580	0.420	0.000
I25.5 Ischaemic cardiomyopathy	0.580	0.420	0.000
F22 Persistent delusional disorders	0.577	0.423	0.000
Q07 Other congenital malformations of nervous system	0.577	0.423	0.000
Q50-Q56 Congenital malformations of genital organs	0.575	0.425	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.575	0.425	0.000
L23 Allergic contact dermatitis	0.574	0.426	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.572	0.428	0.000
F33 Recurrent depressive disorder	0.569	0.431	0.000
G71 Primary disorders of muscles	0.568	0.431	0.000
H54.6 Unqualified visual loss, one eye	0.568	0.432	0.000
H54.5 Low vision, one eye	0.568	0.432	0.000
H54.3 Unqualified visual loss, both eyes	0.568	0.432	0.000
H54.2 Low vision, both eyes	0.568	0.432	0.000
H54.1 Blindness, one eye, low vision, other eye	0.568	0.432	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.568	0.432	0.000
I05-I09 Chronic rheumatic heart diseases	0.568	0.432	0.000
H26.4 After-cataract	0.568	0.432	0.000
F28 Other nonorganic psychotic disorders	0.567	0.433	0.000
F24 Induced delusional disorder	0.567	0.433	0.000
F21 Schizotypal disorder	0.567	0.433	0.000
R47-R49 Symptoms and signs involving speech and voice	0.567	0.433	0.000
F39 Unspecified mood [affective] disorder	0.566	0.434	0.000
H10.9 Conjunctivitis, unspecified	0.564	0.436	0.000
I67.2 Cerebral atherosclerosis	0.562	0.438	0.000
R44.0 Auditory hallucinations	0.562	0.438	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.562	0.438	0.000
H27.8 Other specified disorders of lens	0.561	0.439	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.560	0.440	0.000
R26 Abnormalities of gait and mobility	0.560	0.440	0.000
L50-L54 Urticaria and erythema	0.560	0.440	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.559	0.440	0.000
G03 Meningitis due to other and unspecified causes	0.559	0.440	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.559	0.440	0.000
G00 Bacterial meningitis, not elsewhere classified	0.559	0.440	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.559	0.440	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.559	0.440	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.559	0.440	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.559	0.441	0.000
Q66 Congenital deformities of feet	0.559	0.441	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.559	0.441	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.559	0.441	0.000
E23 Hypofunction and other disorders of pituitary gland	0.558	0.442	0.000
H25.9 Senile cataract, unspecified	0.558	0.442	0.000
G43 Migraine	0.557	0.443	0.000
I20.8 Other forms of angina pectoris	0.556	0.444	0.000
G72 Other myopathies	0.555	0.445	0.000
E53 Deficiency of other B group vitamins	0.555	0.445	0.000
H27.0 Aphakia	0.553	0.447	0.000
F25 Schizoaffective disorders	0.552	0.448	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.552	0.448	0.000
F40 Phobic anxiety disorders	0.551	0.449	0.000
I67.9 Cerebrovascular disease, unspecified	0.549	0.451	0.000
L30 Other dermatitis	0.548	0.452	0.000
E89.3 Postprocedural hypopituitarism	0.548	0.452	0.000
E22 Hyperfunction of pituitary gland	0.547	0.453	0.000
L10-L14 Bullous disorders	0.547	0.453	0.000
R45.1 Restlessness and agitation	0.546	0.454	0.000
Q64 Other congenital malformations of urinary system	0.544	0.456	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.544	0.456	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.543	0.456	0.000
E88 Other metabolic disorders	0.543	0.457	0.001
L27.0 Generalised skin eruption due to drugs and medicaments	0.541	0.459	0.000
F32 Depressive episode	0.540	0.460	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.538	0.461	0.000
Q05.9 Spina bifida, unspecified	0.538	0.462	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.538	0.462	0.000
F34 Persistent mood [affective] disorders	0.537	0.463	0.000
Q06 Other congenital malformations of spinal cord	0.537	0.463	0.000
Q04 Other congenital malformations of brain	0.537	0.463	0.000
Q03 Congenital hydrocephalus	0.537	0.463	0.000
Q01 Encephalocele	0.537	0.463	0.000
Q00 Anencephaly and similar malformations	0.537	0.463	0.000
Q02 Microcephaly	0.537	0.463	0.000
Q63 Other congenital malformations of kidney	0.537	0.463	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.535	0.465	0.000
L60.9 Nail disorder, unspecified	0.535	0.465	0.000
Q18 Other congenital malformations of face and neck	0.534	0.466	0.000
R81 Glycosuria	0.534	0.466	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.533	0.467	0.000
G81 Hemiplegia	0.531	0.469	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.530	0.470	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.529	0.471	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.529	0.471	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.528	0.472	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.527	0.473	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.526	0.473	0.000
G44.8 Other specified headache syndromes	0.526	0.474	0.000
R45.8 Other symptoms and signs involving emotional state	0.526	0.474	0.000
R27.8 Other and unspecified lack of coordination	0.526	0.474	0.000
R45.7 State of emotional shock and stress, unspecified	0.526	0.474	0.000
R45.6 Physical violence	0.526	0.474	0.000
R45.5 Hostility	0.526	0.474	0.000
R45.4 Irritability and anger	0.526	0.474	0.000
R45.3 Demoralisation and apathy	0.526	0.474	0.000
R45.2 Unhappiness	0.526	0.474	0.000
R45.0 Nervousness	0.526	0.474	0.000
G41.8 Other status epilepticus	0.526	0.474	0.000
G41.2 Complex partial status epilepticus	0.526	0.474	0.000
G41.1 Petit mal status epilepticus	0.526	0.474	0.000
G70 Myasthenia gravis and other myoneural disorders	0.525	0.475	0.000
Q12 Congenital lens malformations	0.525	0.475	0.000
G40.8 Other epilepsy	0.525	0.475	0.000
G40.5 Special epileptic syndromes	0.525	0.475	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.525	0.475	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.525	0.475	0.000
H25.2 Senile cataract, morgagnian type	0.524	0.476	0.000
L20 Atopic dermatitis	0.524	0.476	0.000
E24 Cushing's syndrome	0.524	0.476	0.000
E61.9 Deficiency of nutrient element, unspecified	0.522	0.478	0.000
E61.8 Deficiency of other specified nutrient elements	0.522	0.478	0.000
E61.7 Deficiency of multiple nutrient elements	0.522	0.478	0.000
E61.6 Vanadium deficiency	0.522	0.478	0.000
E61.5 Molybdenum deficiency	0.522	0.478	0.000
E61.4 Chromium deficiency	0.522	0.478	0.000
E61.3 Manganese deficiency	0.522	0.478	0.000
E61.2 Magnesium deficiency	0.522	0.478	0.000
E61.0 Copper deficiency	0.522	0.478	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.522	0.478	0.000
G41.9 Status epilepticus, unspecified	0.521	0.479	0.000
Q78 Other osteochondrodysplasias	0.518	0.481	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.518	0.481	0.000
Q76 Congenital malformations of spine and bony thorax	0.518	0.481	0.000
Q75 Other congenital malformations of skull and face bones	0.518	0.481	0.000
Q74 Other congenital malformations of limb(s)	0.518	0.481	0.000
Q73 Reduction defects of unspecified limb	0.518	0.481	0.000
Q72 Reduction defects of lower limb	0.518	0.481	0.000
Q71 Reduction defects of upper limb	0.518	0.481	0.000
Q70 Syndactyly	0.518	0.481	0.000
Q69 Polydactyly	0.518	0.481	0.000
Q68 Other congenital musculoskeletal deformities	0.518	0.481	0.000
E55.9 Vitamin D deficiency, unspecified	0.518	0.482	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.518	0.482	0.000
G44.3 Chronic posttraumatic headache	0.518	0.482	0.000
G44.1 Vascular headache, not elsewhere classified	0.518	0.482	0.000
G50 Disorders of trigeminal nerve	0.517	0.483	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.517	0.483	0.000
E34 Other endocrine disorders	0.517	0.483	0.000
E32 Diseases of thymus	0.517	0.483	0.000
E31 Polyglandular dysfunction	0.517	0.483	0.000
E30 Disorders of puberty, not elsewhere classified	0.517	0.483	0.000
E26 Hyperaldosteronism	0.517	0.483	0.000
E25 Adrenogenital disorders	0.517	0.483	0.000
E20 Hypoparathyroidism	0.517	0.483	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.517	0.483	0.000
Q61.3 Polycystic kidney, unspecified	0.516	0.484	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.516	0.484	0.000
E65-E68 Obesity and other hyperalimentation	0.455	0.486	0.059
F02.8 Dementia in other specified diseases classified elsewhere	0.514	0.486	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.514	0.486	0.000
F02.3 Dementia in Parkinson's disease	0.514	0.486	0.000
F02.2 Dementia in Huntington's disease	0.514	0.486	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.514	0.486	0.000
F02.0 Dementia in Pick's disease	0.514	0.486	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.514	0.486	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.514	0.486	0.000
F07.2 Postconcussional syndrome	0.514	0.486	0.000
F07.1 Postencephalitic syndrome	0.514	0.486	0.000
F07.0 Organic personality disorder	0.514	0.486	0.000
F38 Other mood [affective] disorders	0.514	0.486	0.000
F30 Manic episode	0.514	0.486	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.514	0.486	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.514	0.486	0.000
F79 Unspecified mental retardation	0.513	0.486	0.000
F78 Other mental retardation	0.513	0.486	0.000
F73 Profound mental retardation	0.513	0.486	0.000
F72 Severe mental retardation	0.513	0.486	0.000
F71 Moderate mental retardation	0.513	0.486	0.000
F70 Mild mental retardation	0.513	0.486	0.000
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.513	0.486	0.000
F95 Tic disorders	0.513	0.486	0.000
F94 Disorders of social functioning with onset specific to childhood and adolescence	0.513	0.486	0.000
F93 Emotional disorders with onset specific to childhood	0.513	0.486	0.000
F92 Mixed disorders of conduct and emotions	0.513	0.486	0.000
F91 Conduct disorders	0.513	0.486	0.000
F90 Hyperkinetic disorders	0.513	0.486	0.000
P90-P96 Other disorders originating in the perinatal period	0.513	0.486	0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.513	0.486	0.000
P75-P78 Digestive system disorders of fetus and newborn	0.513	0.486	0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.513	0.486	0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.513	0.486	0.000
P35-P39 Infections specific to the perinatal period	0.513	0.486	0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.513	0.486	0.000
P10-P15 Birth trauma	0.513	0.486	0.000
P05-P08 Disorders related to length of gestation and fetal growth	0.513	0.486	0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.513	0.486	0.000
R96 Other sudden death, cause unknown	0.513	0.487	0.000
R95 Sudden infant death syndrome	0.513	0.487	0.000
R99 Other ill-defined and unspecified causes of mortality	0.513	0.487	0.000
R98 Unattended death	0.513	0.487	0.000
E29 Testicular dysfunction	0.512	0.487	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.512	0.487	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.512	0.487	0.000
E87.0 Hyperosmolality and hypernatraemia	0.512	0.488	0.000
Z95.4 Presence of other heart-valve replacement	0.512	0.488	0.000
I02 Rheumatic chorea	0.512	0.488	0.000
I01 Rheumatic fever with heart involvement	0.512	0.488	0.000
I00 Rheumatic fever without mention of heart involvement	0.512	0.488	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.512	0.488	0.000
R43.2 Parageusia	0.512	0.488	0.000
R43.1 Parosmia	0.512	0.488	0.000
R43.0 Anosmia	0.512	0.488	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.511	0.489	0.000
R23.8 Other and unspecified skin changes	0.511	0.489	0.000
R89 Abnormal findings in specimens from other organs, systems and tissues	0.510	0.490	0.000
L25 Unspecified contact dermatitis	0.509	0.491	0.000
L24 Irritant contact dermatitis	0.509	0.491	0.000
L21 Seborrhoeic dermatitis	0.509	0.491	0.000
L26 Exfoliative dermatitis	0.509	0.491	0.000
L22 Diaper [napkin] dermatitis	0.509	0.491	0.000
E28 Ovarian dysfunction	0.508	0.492	0.000
Q65 Congenital deformities of hip	0.507	0.493	0.000
I73 Other peripheral vascular diseases	0.507	0.493	0.000
R01.0 Benign and innocent cardiac murmurs	0.507	0.493	0.000
H54.4 Blindness, one eye	0.506	0.494	0.000
L60.3 Nail dystrophy	0.506	0.494	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.505	0.495	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.505	0.495	0.000
E70.3 Albinism	0.505	0.495	0.000
E70.2 Disorders of tyrosine metabolism	0.505	0.495	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations