TreeWAS – Variant ID: rs16891156

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000
I20.9 Angina pectoris, unspecified	1.000	0.000
I25.9 Chronic ischaemic heart disease, unspecified	1.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	1.000	0.000
I25.2 Old myocardial infarction	1.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	1.000	0.000
Z95.5 Presence of coronary angioplasty implant and graft	1.000	0.000
Z95.1 Presence of aortocoronary bypass graft	1.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	1.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000
I21 Acute myocardial infarction	1.000	0.000
I20 Angina pectoris	1.000	0.000
Z95 Presence of cardiac and vascular implants and grafts	1.000	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	1.000	0.000
I30-I52 Other forms of heart disease	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
I20.0 Unstable angina	1.000	0.000
I10 Essential (primary) hypertension	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
E78.5 Hyperlipidaemia, unspecified	1.000	0.000
I10-I15 Hypertensive diseases	1.000	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	1.000	0.000
E70-E90 Metabolic disorders	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
I77 Other disorders of arteries and arterioles	1.000	0.000
Z92 Personal history of medical treatment	1.000	0.000
I35 Nonrheumatic aortic valve disorders	0.999	0.001
I21.9 Acute myocardial infarction, unspecified	0.999	0.001
Chapter II Neoplasms	0.999	0.001
I50 Heart failure	0.999	0.001
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.999	0.001
R07 Pain in throat and chest	0.998	0.002
I73 Other peripheral vascular diseases	0.998	0.002
R07.4 Chest pain, unspecified	0.998	0.002
I73.9 Peripheral vascular disease, unspecified	0.998	0.002
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.997	0.003
I35.0 Aortic (valve) stenosis	0.997	0.003
I77.1 Stricture of artery	0.997	0.003
Z92.2 Personal history of long-term (current) use of other medicaments	0.995	0.005
I21.1 Acute transmural myocardial infarction of inferior wall	0.995	0.005
Z92.1 Personal history of long-term (current) use of anticoagulants	0.994	0.006
Z86 Personal history of certain other diseases	0.990	0.010
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.990	0.010
Z86.4 Personal history of psychoactive substance abuse	0.988	0.012
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.986	0.014
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.985	0.015
I20.8 Other forms of angina pectoris	0.984	0.016
I51 Complications and ill-defined descriptions of heart disease	0.983	0.017
Chapter V Mental and behavioural disorders	0.982	0.018
Z80 Family history of malignant neoplasm	0.981	0.019
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.980	0.020
I60-I69 Cerebrovascular diseases	0.979	0.021
I50.0 Congestive heart failure	0.977	0.023
I50.1 Left ventricular failure	0.977	0.023
Z70-Z76 Persons encountering health services in other circumstances	0.972	0.028
Z95.8 Presence of other cardiac and vascular implants and grafts	0.970	0.030
Chapter XX External causes of morbidity and mortality	0.967	0.033
Chapter XI Diseases of the digestive system	0.967	0.033
D37-D48 Neoplasms of uncertain or unknown behaviour	0.963	0.037
K90-K93 Other diseases of the digestive system	0.962	0.038
Z80.3 Family history of malignant neoplasm of breast	0.959	0.041
R94 Abnormal results of function studies	0.959	0.041
K92 Other diseases of digestive system	0.957	0.043
I31 Other diseases of pericardium	0.953	0.047
Chapter I Certain infectious and parasitic diseases	0.953	0.047
Z95.4 Presence of other heart-valve replacement	0.950	0.050
I63 Cerebral infarction	0.949	0.051
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.947	0.053
Chapter X Diseases of the respiratory system	0.947	0.053
K92.1 Melaena	0.943	0.057
S00-S09 Injuries to the head	0.939	0.061
R94.5 Abnormal results of liver function studies	0.930	0.070
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.929	0.071
Z72 Problems related to lifestyle	0.924	0.076
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.923	0.077
I77.9 Disorder of arteries and arterioles, unspecified	0.920	0.080
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.917	0.083
I71 Aortic aneurysm and dissection	0.917	0.083
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.916	0.084
I22 Subsequent myocardial infarction	0.913	0.087
J20-J22 Other acute lower respiratory infections	0.912	0.088
I51.7 Cardiomegaly	0.910	0.090
Z95.2 Presence of prosthetic heart valve	0.910	0.090
Z72.0 Tobacco use	0.909	0.091
Z80.4 Family history of malignant neoplasm of genital organs	0.907	0.093
S70-S79 Injuries to the hip and thigh	0.907	0.093
T81 Complications of procedures, not elsewhere classified	0.906	0.094
Chapter VIII Diseases of the ear and mastoid process	0.903	0.097
I24 Other acute ischaemic heart diseases	0.902	0.098
I64 Stroke, not specified as haemorrhage or infarction	0.900	0.100
R07.3 Other chest pain	0.900	0.100
C83 Diffuse non-Hodgkin's lymphoma	0.899	0.101
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.899	0.101
I31.3 Pericardial effusion (noninflammatory)	0.897	0.103
C50-C50 Malignant neoplasm of breast	0.896	0.104
Chapter VII Diseases of the eye and adnexa	0.895	0.105
B95-B98 Bacterial, viral and other infectious agents	0.895	0.105
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.893	0.107
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.891	0.109
T88 Other complications of surgical and medical care, not elsewhere classified	0.891	0.109
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.890	0.110
I51.9 Heart disease, unspecified	0.889	0.111
R93 Abnormal findings on diagnostic imaging of other body structures	0.888	0.112
J22 Unspecified acute lower respiratory infection	0.886	0.114
T36-T50 Poisoning by drugs, medicaments and biological substances	0.883	0.117
F30-F39 Mood [affective] disorders	0.882	0.118
Z40-Z54 Persons encountering health services for specific procedures and health care	0.880	0.120
F40-F48 Neurotic, stress-related and somatoform disorders	0.879	0.121
A30-A49 Other bacterial diseases	0.878	0.122
S01 Open wound of head	0.876	0.124
I35.8 Other aortic valve disorders	0.873	0.127
C64-C68 Malignant neoplasms of urinary tract	0.872	0.128
I95-I99 Other and unspecified disorders of the circulatory system	0.867	0.133
I50.9 Heart failure, unspecified	0.866	0.134
I21.2 Acute transmural myocardial infarction of other sites	0.866	0.134
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.864	0.136
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.855	0.145
Z86.7 Personal history of diseases of the circulatory system	0.855	0.145
E20-E35 Disorders of other endocrine glands	0.855	0.145
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.855	0.145
K70-K77 Diseases of liver	0.854	0.146
D70-D77 Other diseases of blood and blood-forming organs	0.853	0.147
K50-K52 Noninfective enteritis and colitis	0.852	0.148
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.852	0.148
I77.8 Other specified disorders of arteries and arterioles	0.851	0.149
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.851	0.149
E87 Other disorders of fluid, electrolyte and acid-base balance	0.850	0.150
I05-I09 Chronic rheumatic heart diseases	0.849	0.151
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.849	0.151
I35.2 Aortic (valve) stenosis with insufficiency	0.848	0.152
Z88.6 Personal history of allergy to analgesic agent	0.847	0.153
I63.8 Other cerebral infarction	0.847	0.153
Z50 Care involving use of rehabilitation procedures	0.846	0.154
R30-R39 Symptoms and signs involving the urinary system	0.842	0.158
I34 Nonrheumatic mitral valve disorders	0.841	0.159
Z88.0 Personal history of allergy to penicillin	0.841	0.159
T87 Complications peculiar to reattachment and amputation	0.837	0.163
Chapter XXII Codes for special purposes	0.835	0.165
I45 Other conduction disorders	0.834	0.165
X60-X84 Intentional self-harm	0.834	0.166
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.834	0.166
Z95.3 Presence of xenogenic heart valve	0.833	0.167
I51.6 Cardiovascular disease, unspecified	0.831	0.169
K92.2 Gastro-intestinal haemorrhage, unspecified	0.829	0.171
S01.9 Open wound of head, part unspecified	0.828	0.172
D00-D09 In situ neoplasms	0.828	0.172
R39 Other symptoms and signs involving the urinary system	0.823	0.177
C50 Malignant neoplasm of breast	0.823	0.177
Chapter VI Diseases of the nervous system	0.822	0.178
I74 Arterial embolism and thrombosis	0.822	0.178
I22.9 Subsequent myocardial infarction of unspecified site	0.821	0.179
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.819	0.181
H30-H36 Disorders of choroid and retina	0.819	0.181
F33 Recurrent depressive disorder	0.817	0.183
T93 Sequelae of injuries of lower limb	0.816	0.184
I77.6 Arteritis, unspecified	0.815	0.185
D60-D64 Aplastic and other anaemias	0.815	0.185
K90 Intestinal malabsorption	0.812	0.187
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.811	0.189
J30-J39 Other diseases of upper respiratory tract	0.810	0.190
I21.3 Acute transmural myocardial infarction of unspecified site	0.809	0.191
K50 Crohn's disease [regional enteritis]	0.808	0.192
R39.1 Other difficulties with micturition	0.808	0.192
I35.1 Aortic (valve) insufficiency	0.807	0.193
Z92.6 Personal history of chemotherapy for neoplastic disease	0.806	0.194
T82.3 Mechanical complication of other vascular grafts	0.806	0.194
C64 Malignant neoplasm of kidney, except renal pelvis	0.806	0.194
E87.5 Hyperkalaemia	0.806	0.194
I77.0 Arteriovenous fistula, acquired	0.805	0.195
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.805	0.195
R07.2 Precordial pain	0.804	0.196
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.803	0.197
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.799	0.201
I21.0 Acute transmural myocardial infarction of anterior wall	0.799	0.201
T66-T78 Other and unspecified effects of external causes	0.799	0.201
K92.0 Haematemesis	0.798	0.202
R00 Abnormalities of heart beat	0.796	0.204
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.795	0.205
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.795	0.205
A49 Bacterial infection of unspecified site	0.792	0.208
Z50.0 Cardiac rehabilitation	0.791	0.209
H65-H75 Diseases of middle ear and mastoid	0.791	0.209
I31.9 Disease of pericardium, unspecified	0.790	0.209
Z99.3 Dependence on wheelchair	0.790	0.210
C81 Hodgkin's disease	0.789	0.211
E73 Lactose intolerance	0.787	0.213
I12 Hypertensive renal disease	0.786	0.213
D70 Agranulocytosis	0.786	0.214
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.785	0.215
I71.0 Dissection of aorta [any part]	0.782	0.218
I51.4 Myocarditis, unspecified	0.780	0.220
T88.7 Unspecified adverse effect of drug or medicament	0.779	0.221
I83 Varicose veins of lower extremities	0.777	0.223
Z89 Acquired absence of limb	0.775	0.225
I33 Acute and subacute endocarditis	0.775	0.225
C50.4 Upper-outer quadrant of breast	0.773	0.227
T82.0 Mechanical complication of heart valve prosthesis	0.772	0.228
Z93 Artificial opening status	0.771	0.229
R47-R49 Symptoms and signs involving speech and voice	0.771	0.229
Z71.8 Other specified counselling	0.771	0.229
S72 Fracture of femur	0.770	0.230
X40-X49 Accidental poisoning by and exposure to noxious substances	0.770	0.230
E88 Other metabolic disorders	0.769	0.231
R02 Gangrene, not elsewhere classified	0.769	0.231
C83.3 Large cell (diffuse)	0.765	0.235
I20.1 Angina pectoris with documented spasm	0.765	0.235
Z50.5 Speech therapy	0.765	0.235
Z71.3 Dietary counselling and surveillance	0.764	0.236
S40-S49 Injuries to the shoulder and upper arm	0.763	0.237
R50-R69 General symptoms and signs	0.763	0.237
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.762	0.238
F17 Mental and behavioural disorders due to use of tobacco	0.762	0.238
I70 Atherosclerosis	0.761	0.239
R94.4 Abnormal results of kidney function studies	0.760	0.240
I63.9 Cerebral infarction, unspecified	0.760	0.240
I65.2 Occlusion and stenosis of carotid artery	0.759	0.241
S02 Fracture of skull and facial bones	0.759	0.241
Z80.9 Family history of malignant neoplasm, unspecified	0.758	0.241
D46 Myelodysplastic syndromes	0.757	0.243
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.757	0.243
K74 Fibrosis and cirrhosis of liver	0.757	0.243
X10-X19 Contact with heat and hot substances	0.756	0.244
R94.3 Abnormal results of cardiovascular function studies	0.756	0.244
R90 Abnormal findings on diagnostic imaging of central nervous system	0.755	0.245
S79 Other and unspecified injuries of hip and thigh	0.755	0.245
G90-G99 Other disorders of the nervous system	0.755	0.245
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.754	0.246
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.753	0.247
Z80.5 Family history of malignant neoplasm of urinary tract	0.753	0.247
S20-S29 Injuries to the thorax	0.753	0.247
C71 Malignant neoplasm of brain	0.753	0.247
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.752	0.248
J90-J94 Other diseases of pleura	0.751	0.249
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.751	0.249
D64 Other anaemias	0.750	0.250
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.750	0.250
I24.8 Other forms of acute ischaemic heart disease	0.750	0.250
Y60-Y69 Misadventures to patients during surgical and medical care	0.749	0.251
T81.8 Other complications of procedures, not elsewhere classified	0.748	0.252
I72 Other aneurysm	0.747	0.253
F33.9 Recurrent depressive disorder, unspecified	0.747	0.253
T90 Sequelae of injuries of head	0.747	0.253
R53 Malaise and fatigue	0.747	0.253
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.746	0.253
Y51 Drugs primarily affecting the autonomic nervous system	0.745	0.255
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.745	0.255
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.744	0.256
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.744	0.256
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.744	0.256
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.744	0.256
Z94 Transplanted organ and tissue status	0.744	0.256
F10 Mental and behavioural disorders due to use of alcohol	0.743	0.257
E83 Disorders of mineral metabolism	0.743	0.257
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.742	0.257
I34.0 Mitral (valve) insufficiency	0.742	0.258
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.742	0.258
J35 Chronic diseases of tonsils and adenoids	0.742	0.258
K50.1 Crohn's disease of large intestine	0.741	0.259
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.741	0.259
Z95.0 Presence of cardiac pacemaker	0.741	0.259
C73 Malignant neoplasm of thyroid gland	0.741	0.259
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.740	0.260
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.739	0.261
I22.1 Subsequent myocardial infarction of inferior wall	0.739	0.261
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.737	0.263
I11 Hypertensive heart disease	0.737	0.263
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.736	0.263
I45.1 Other and unspecified right bundle-branch block	0.736	0.263
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.736	0.264
T93.8 Sequelae of other specified injuries of lower limb	0.736	0.264
E50-E64 Other nutritional deficiencies	0.735	0.265
S06 Intracranial injury	0.733	0.267
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.732	0.268
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.732	0.268
Y41 Other systemic anti-infectives and antiparasitics	0.731	0.269
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.731	0.269
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.729	0.271
K50.9 Crohn's disease, unspecified	0.728	0.272
Z45 Adjustment and management of implanted device	0.728	0.272
R73 Elevated blood glucose level	0.726	0.274
I95 Hypotension	0.726	0.274
S10-S19 Injuries to the neck	0.726	0.274
E78.2 Mixed hyperlipidaemia	0.724	0.275
T79-T79 Certain early complications of trauma	0.724	0.276
X20-X29 Contact with venomous animals and plants	0.724	0.276
T82.1 Mechanical complication of cardiac electronic device	0.723	0.277
I78 Diseases of capillaries	0.723	0.277
S05 Injury of eye and orbit	0.722	0.278
I83.1 Varicose veins of lower extremities with inflammation	0.722	0.278
H80-H83 Diseases of inner ear	0.722	0.278
I86 Varicose veins of other sites	0.722	0.278
E27 Other disorders of adrenal gland	0.721	0.279
F41 Other anxiety disorders	0.721	0.279
I85 Oesophageal varices	0.721	0.279
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.721	0.279
R00.1 Bradycardia, unspecified	0.721	0.279
F60-F69 Disorders of adult personality and behaviour	0.720	0.279
J80-J84 Other respiratory diseases principally affecting the interstitium	0.720	0.280
Z99.2 Dependence on renal dialysis	0.720	0.280
I21.4 Acute subendocardial myocardial infarction	0.720	0.280
H43-H45 Disorders of vitreous body and globe	0.720	0.280
K92.9 Disease of digestive system, unspecified	0.719	0.281
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.719	0.281
I35.9 Aortic valve disorder, unspecified	0.719	0.281
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.719	0.281
T88.4 Failed or difficult intubation	0.719	0.281
Z99.1 Dependence on respirator	0.718	0.282
H40-H42 Glaucoma	0.718	0.282
S90-S99 Injuries to the ankle and foot	0.717	0.282
Z82.3 Family history of stroke	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
E78.8 Other disorders of lipoprotein metabolism	0.717	0.283
E78.6 Lipoprotein deficiency	0.717	0.283
E78.4 Other hyperlipidaemia	0.717	0.283
E78.3 Hyperchylomicronaemia	0.717	0.283
E78.1 Pure hyperglyceridaemia	0.717	0.283
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.4 Coronary artery aneurysm	0.717	0.283
I25.3 Aneurysm of heart	0.717	0.283
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I37 Pulmonary valve disorders	0.717	0.283
I36 Nonrheumatic tricuspid valve disorders	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
I30 Acute pericarditis	0.717	0.283
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.717	0.283
Z84 Family history of other conditions	0.717	0.283
Z81 Family history of mental and behavioural disorders	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I15 Secondary hypertension	0.717	0.283
I13 Hypertensive heart and renal disease	0.717	0.283
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.717	0.283
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.717	0.283
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.717	0.283
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.717	0.283
Z82.2 Family history of deafness and hearing loss	0.717	0.283
Z82.1 Family history of blindness and visual loss	0.717	0.283
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.717	0.283
E85 Amyloidosis	0.717	0.283
E84 Cystic fibrosis	0.717	0.283
E79 Disorders of purine and pyrimidine metabolism	0.717	0.283
E77 Disorders of glycoprotein metabolism	0.717	0.283
E76 Disorders of glycosaminoglycan metabolism	0.717	0.283
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.717	0.283
E74 Other disorders of carbohydrate metabolism	0.717	0.283
E72 Other disorders of amino-acid metabolism	0.717	0.283
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.717	0.283
E70 Disorders of aromatic amino-acid metabolism	0.717	0.283
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.717	0.283
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
I77.5 Necrosis of artery	0.717	0.283
I77.4 Coeliac artery compression syndrome	0.717	0.283
I77.3 Arterial fibromuscular dysplasia	0.717	0.283
I77.2 Rupture of artery	0.717	0.283
Z92.9 Personal history of medical treatment, unspecified	0.717	0.283
Z92.8 Personal history of other medical treatment	0.717	0.283
Z92.5 Personal history of rehabilitation measures	0.717	0.283
I24.9 Acute ischaemic heart disease, unspecified	0.716	0.284
C85.1 B-cell lymphoma, unspecified	0.716	0.284
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.716	0.284
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.716	0.284
R07.1 Chest pain on breathing	0.716	0.284
I73.8 Other specified peripheral vascular diseases	0.716	0.284
I73.1 Thromboangiitis obliterans [Buerger]	0.716	0.284
T86 Failure and rejection of transplanted organs and tissues	0.715	0.285
T80 Complications following infusion, transfusion and therapeutic injection	0.715	0.285
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.714	0.285
Z88.3 Personal history of allergy to other anti-infective agents	0.714	0.286
I46 Cardiac arrest	0.714	0.286
F45 Somatoform disorders	0.713	0.286
S00 Superficial injury of head	0.713	0.287
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.713	0.287
S01.8 Open wound of other parts of head	0.713	0.287
H90-H95 Other disorders of ear	0.712	0.287
J60-J70 Lung diseases due to external agents	0.712	0.288
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.712	0.288
Z40 Prophylactic surgery	0.711	0.289
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.711	0.289
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.710	0.290
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.710	0.290
T82.4 Mechanical complication of vascular dialysis catheter	0.710	0.290
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.710	0.290
I62 Other nontraumatic intracranial haemorrhage	0.709	0.290
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.709	0.291
E86 Volume depletion	0.709	0.291
G93 Other disorders of brain	0.708	0.292
Z88.5 Personal history of allergy to narcotic agent	0.708	0.292
H36 Retinal disorders in diseases classified elsewhere	0.707	0.293
T98 Sequelae of other and unspecified effects of external causes	0.707	0.293
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.707	0.293
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.707	0.293
C95 Leukaemia of unspecified cell type	0.707	0.293
C94 Other leukaemias of specified cell type	0.707	0.293
C93 Monocytic leukaemia	0.707	0.293
C88 Malignant immunoproliferative diseases	0.707	0.293
C86 Other specified types of T/NK-cell lymphoma	0.707	0.293
C84 Peripheral and cutaneous T-cell lymphomas	0.707	0.293
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.706	0.294
I51.5 Myocardial degeneration	0.705	0.295
I51.3 Intracardiac thrombosis, not elsewhere classified	0.705	0.295
I51.2 Rupture of papillary muscle, not elsewhere classified	0.705	0.295
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.705	0.295
I51.0 Cardiac septal defect, acquired	0.705	0.295
E40-E46 Malnutrition	0.704	0.295
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.704	0.296
F80-F89 Disorders of psychological development	0.704	0.296
F70-F79 Mental retardation	0.704	0.296
D64.9 Anaemia, unspecified	0.704	0.296
F17.1 Harmful use	0.704	0.296
D48.5 Skin	0.704	0.296
I60 Subarachnoid haemorrhage	0.704	0.296
I25.5 Ischaemic cardiomyopathy	0.703	0.296
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.703	0.297
Z80.6 Family history of leukaemia	0.703	0.297
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.703	0.297
Z75 Problems related to medical facilities and other health care	0.703	0.297
F31 Bipolar affective disorder	0.703	0.297
R92 Abnormal findings on diagnostic imaging of breast	0.703	0.297
I98 Other disorders of circulatory system in diseases classified elsewhere	0.702	0.298
I68 Cerebrovascular disorders in diseases classified elsewhere	0.702	0.298
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.702	0.298
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.701	0.299
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.700	0.300
E80 Disorders of porphyrin and bilirubin metabolism	0.700	0.300
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.700	0.300
C91 Lymphoid leukaemia	0.699	0.301
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.699	0.301
D48.1 Connective and other soft tissue	0.699	0.301
B15-B19 Viral hepatitis	0.698	0.302
K74.6 Other and unspecified cirrhosis of liver	0.698	0.302
S70 Superficial injury of hip and thigh	0.697	0.303
Z76 Persons encountering health services in other circumstances	0.697	0.303
Z70 Counselling related to sexual attitude, behaviour and orientation	0.697	0.303
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.696	0.304
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.695	0.305
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.695	0.305
T87.4 Infection of amputation stump	0.694	0.306
Y35-Y36 Legal intervention and operations of war	0.693	0.306
Y10-Y34 Event of undetermined intent	0.693	0.306
Y00-Y09 Assault	0.693	0.306
X85-X99 Assault	0.693	0.306
X58-X59 Accidental exposure to other and unspecified factors	0.693	0.306
X50-X57 Overexertion, travel and privation	0.693	0.306
X30-X39 Exposure to forces of nature	0.693	0.306
X00-X09 Exposure to smoke, fire and flames	0.693	0.306
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.693	0.306
W75-W84 Other accidental threats to breathing	0.693	0.306
W65-W74 Accidental drowning and submersion	0.693	0.306
W50-W64 Exposure to animate mechanical forces	0.693	0.306
V98-V99 Other and unspecified transport accidents	0.693	0.306
V95-V97 Air and space transport accidents	0.693	0.306
V90-V94 Water transport accidents	0.693	0.306
V80-V89 Other land transport accidents	0.693	0.306
V70-V79 Bus occupant injured in transport accident	0.693	0.306
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.693	0.306
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.693	0.306
V40-V49 Car occupant injured in transport accident	0.693	0.306
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.693	0.306
V01-V09 Pedestrian injured in transport accident	0.693	0.306
K90.0 Coeliac disease	0.693	0.307
A46 Erysipelas	0.693	0.307
D39.1 Ovary	0.692	0.308
J00-J06 Acute upper respiratory infections	0.691	0.309
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.691	0.309
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.690	0.310
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.690	0.310
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.690	0.310
K81 Cholecystitis	0.690	0.310
Y52 Agents primarily affecting the cardiovascular system	0.690	0.310
A49.0 Staphylococcal infection, unspecified	0.690	0.310
K93 Disorders of other digestive organs in diseases classified elsewhere	0.690	0.310
C92 Myeloid leukaemia	0.689	0.310
G30-G32 Other degenerative diseases of the nervous system	0.689	0.311
H31 Other disorders of choroid	0.689	0.311
Z92.0 Personal history of contraception	0.689	0.311
H65 Nonsuppurative otitis media	0.688	0.312
Z42 Follow-up care involving plastic surgery	0.688	0.312
Z88.2 Personal history of allergy to sulphonamides	0.688	0.312
R94.8 Abnormal results of function studies of other organs and systems	0.687	0.313
R94.7 Abnormal results of other endocrine function studies	0.687	0.313

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations