TreeWAS – Variant ID: rs2954020

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	1.000	0.000	0.000
E78.5 Hyperlipidaemia, unspecified	0.999	0.001	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.992	0.008	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.992	0.008	0.000
I25.2 Old myocardial infarction	0.985	0.015	0.000
E78.2 Mixed hyperlipidaemia	0.952	0.048	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.896	0.104	0.000
E78.1 Pure hyperglyceridaemia	0.882	0.118	0.000
I25.3 Aneurysm of heart	0.847	0.153	0.000
I25.4 Coronary artery aneurysm	0.822	0.178	0.000
I25.5 Ischaemic cardiomyopathy	0.780	0.220	0.000
E78.4 Other hyperlipidaemia	0.756	0.244	0.000
E78.3 Hyperchylomicronaemia	0.717	0.283	0.000
I25.6 Silent myocardial ischaemia	0.700	0.300	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.685	0.315	0.000
E78.6 Lipoprotein deficiency	0.679	0.321	0.000
E78.8 Other disorders of lipoprotein metabolism	0.659	0.341	0.000
I50.1 Left ventricular failure	0.492	0.508	0.000
I20-I25 Ischaemic heart diseases	0.483	0.517	0.000
I20 Angina pectoris	0.460	0.540	0.000
I20.8 Other forms of angina pectoris	0.436	0.564	0.000
I20.0 Unstable angina	0.385	0.615	0.000
I20.9 Angina pectoris, unspecified	0.380	0.620	0.000
I22 Subsequent myocardial infarction	0.343	0.657	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.322	0.678	0.000
I21 Acute myocardial infarction	0.318	0.682	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.317	0.683	0.000
I50 Heart failure	0.306	0.694	0.000
I50.0 Congestive heart failure	0.281	0.719	0.000
I23 Certain current complications following acute myocardial infarction	0.270	0.730	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.228	0.772	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.228	0.772	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.226	0.774	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.194	0.806	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.194	0.806	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.194	0.806	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.194	0.806	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.194	0.806	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.194	0.806	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.194	0.806	0.000
I20.1 Angina pectoris with documented spasm	0.192	0.808	0.000
I50.9 Heart failure, unspecified	0.180	0.820	0.000
I24 Other acute ischaemic heart diseases	0.177	0.823	0.000
I22.8 Subsequent myocardial infarction of other sites	0.168	0.832	0.000
I21.4 Acute subendocardial myocardial infarction	0.148	0.852	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.140	0.860	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.135	0.865	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.132	0.868	0.000
I24.1 Dressler's syndrome	0.124	0.876	0.000
I23.8 Other current complications following acute myocardial infarction	0.117	0.882	0.001
I21.3 Acute transmural myocardial infarction of unspecified site	0.098	0.901	0.001
I24.9 Acute ischaemic heart disease, unspecified	0.084	0.916	0.000
Z95.1 Presence of aortocoronary bypass graft	0.044	0.956	0.000
I21.9 Acute myocardial infarction, unspecified	0.042	0.958	0.000
I24.8 Other forms of acute ischaemic heart disease	0.026	0.974	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.975	0.025
E27.4 Other and unspecified adrenocortical insufficiency	0.024	0.976	0.000
E27 Other disorders of adrenal gland	0.020	0.980	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.019	0.981	0.000
K76.6 Portal hypertension	0.018	0.982	0.000
E27.1 Primary adrenocortical insufficiency	0.017	0.983	0.000
K76 Other diseases of liver	0.016	0.984	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.016	0.984	0.000
E27.9 Disorder of adrenal gland, unspecified	0.016	0.984	0.000
E27.2 Addisonian crisis	0.015	0.984	0.000
E27.5 Adrenomedullary hyperfunction	0.014	0.986	0.000
E27.0 Other adrenocortical overactivity	0.014	0.986	0.000
K76.9 Liver disease, unspecified	0.014	0.986	0.000
N85.4 Malposition of uterus	0.000	0.987	0.013
K76.7 Hepatorenal syndrome	0.013	0.987	0.000
H60.9 Otitis externa, unspecified	0.000	0.987	0.013
U89.8 Agent resistant to other single specified antibiotic	0.012	0.988	0.000
K76.5 Hepatic veno-occlusive disease	0.012	0.988	0.000
K76.4 Peliosis hepatis	0.012	0.988	0.000
K76.3 Infarction of liver	0.012	0.988	0.000
K76.2 Central haemorrhagic necrosis of liver	0.012	0.988	0.000
E27.8 Other specified disorders of adrenal gland	0.012	0.988	0.000
E28.2 Polycystic ovarian syndrome	0.012	0.988	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.011	0.989	0.000
U89 Agent resistant to other and unspecified antibiotics	0.011	0.989	0.000
U51 Admission status on psychiatric patients	0.011	0.989	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.011	0.989	0.000
E28 Ovarian dysfunction	0.010	0.990	0.000
K76.1 Chronic passive congestion of liver	0.010	0.990	0.000
U80 Agent resistant to penicillin and related antibiotics	0.010	0.990	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.010	0.990	0.000
E20-E35 Disorders of other endocrine glands	0.010	0.990	0.000
Chapter XXII Codes for special purposes	0.009	0.991	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.009	0.991	0.000
U80.1 Methicillin resistant agent	0.009	0.991	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.009	0.991	0.000
E24 Cushing's syndrome	0.009	0.991	0.000
U51.2 Previously admitted to a psychiatric hospital of another provider	0.009	0.991	0.000
E23 Hypofunction and other disorders of pituitary gland	0.008	0.992	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.008	0.992	0.000
U50 Level of care administered to neonates	0.008	0.992	0.000
U07 Emergency use of U07	0.008	0.992	0.000
U06 Emergency use of U06	0.008	0.992	0.000
U04 Severe acute respiratory syndrome [SARS]	0.008	0.992	0.000
U52 First in a series of a regular day/night admissions	0.008	0.992	0.000
U89.9 Agent resistant to unspecified antibiotic	0.008	0.992	0.000
E24.9 Cushing's syndrome, unspecified	0.008	0.992	0.000
U88 Agent resistant to multiple antibiotics	0.008	0.992	0.000
E28.9 Ovarian dysfunction, unspecified	0.007	0.992	0.000
E28.8 Other ovarian dysfunction	0.007	0.992	0.000
E28.1 Androgen excess	0.007	0.992	0.000
E28.0 Oestrogen excess	0.007	0.992	0.000
E23.6 Other disorders of pituitary gland	0.007	0.992	0.000
E23.2 Diabetes insipidus	0.007	0.992	0.000
U84 Resistance to other antimicrobial drugs	0.007	0.993	0.000
U83 Resistance to other antibiotics	0.007	0.993	0.000
U82 Resistance to betalactam antibiotics	0.007	0.993	0.000
U85 Resistance to antineoplastic drugs	0.007	0.993	0.000
U81.0 Vancomycin resistant agent	0.007	0.993	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.007	0.993	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.007	0.993	0.000
E32 Diseases of thymus	0.007	0.993	0.000
E30 Disorders of puberty, not elsewhere classified	0.007	0.993	0.000
E31 Polyglandular dysfunction	0.007	0.993	0.000
E20 Hypoparathyroidism	0.007	0.993	0.000
U80.0 Penicillin resistant agent	0.007	0.993	0.000
E24.0 Pituitary-dependent Cushing's disease	0.007	0.993	0.000
H60 Otitis externa	0.000	0.993	0.007
E25 Adrenogenital disorders	0.007	0.993	0.000
E28.3 Primary ovarian failure	0.007	0.993	0.000
E70-E90 Metabolic disorders	0.007	0.993	0.000
E24.8 Other Cushing's syndrome	0.006	0.993	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.006	0.993	0.000
E24.3 Ectopic ACTH syndrome	0.006	0.993	0.000
E24.1 Nelson's syndrome	0.006	0.993	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.994	0.006
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.006	0.994	0.000
E23.1 Drug-induced hypopituitarism	0.006	0.994	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.006	0.994	0.000
H60.4 Cholesteatoma of external ear	0.000	0.994	0.006
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.006	0.994	0.000
U06.9 Emergency use of U06.9	0.006	0.994	0.000
U06.8 Emergency use of U06.8	0.006	0.994	0.000
U06.7 Emergency use of U06.7	0.006	0.994	0.000
U06.6 Emergency use of U06.6	0.006	0.994	0.000
U06.5 Emergency use of U06.5	0.006	0.994	0.000
U06.4 Emergency use of U06.4	0.006	0.994	0.000
U06.3 Emergency use of U06.3	0.006	0.994	0.000
U06.2 Emergency use of U06.2	0.006	0.994	0.000
U06.1 Emergency use of U06.1	0.006	0.994	0.000
U06.0 Emergency use of U06.0	0.006	0.994	0.000
U07.9 Emergency use of U07.9	0.006	0.994	0.000
U07.8 Emergency use of U07.8	0.006	0.994	0.000
U07.7 Emergency use of U07.7	0.006	0.994	0.000
U07.6 Emergency use of U07.6	0.006	0.994	0.000
U07.5 Emergency use of U07.5	0.006	0.994	0.000
U07.4 Emergency use of U07.4	0.006	0.994	0.000
U07.3 Emergency use of U07.3	0.006	0.994	0.000
U07.2 Emergency use of U07.2	0.006	0.994	0.000
U07.1 Emergency use of U07.1	0.006	0.994	0.000
U07.0 Emergency use of U07.0	0.006	0.994	0.000
U50.9 Inquest Adjourned Death	0.006	0.994	0.000
U50.3 Level of care administered to neonates (Maximal Intensive Care)	0.006	0.994	0.000
U50.2 Level of care administered to neonates (High Dependancy Intensive Care)	0.006	0.994	0.000
U50.1 Level of care administered to neonates (Special Care)	0.006	0.994	0.000
U50.0 Level of care administered to neonates (Normal Care)	0.006	0.994	0.000
H60.3 Other infective otitis externa	0.000	0.994	0.006
E23.7 Disorder of pituitary gland, unspecified	0.006	0.994	0.000
H60.1 Cellulitis of external ear	0.000	0.994	0.006
D69.6 Thrombocytopenia, unspecified	0.006	0.994	0.000
E24.2 Drug-induced Cushing's syndrome	0.006	0.994	0.000
E34 Other endocrine disorders	0.006	0.994	0.000
E26 Hyperaldosteronism	0.006	0.994	0.000
U82.9 Resistance to betalactam antibiotics, unspecified	0.005	0.994	0.000
U82.8 Resistance to other betalactam antibiotics	0.005	0.994	0.000
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.005	0.994	0.000
U82.1 Resistance to methicillin	0.005	0.994	0.000
U82.0 Resistance to penicillin	0.005	0.994	0.000
U83.9 Resistance to unspecified antibiotic	0.005	0.994	0.000
U83.8 Resistance to other single specified antibiotic	0.005	0.994	0.000
U83.7 Resistance to multiple antibiotics	0.005	0.994	0.000
U83.2 Resistance to quinolones	0.005	0.994	0.000
U83.1 Resistance to other vancomycin related antibiotics	0.005	0.994	0.000
U83.0 Resistance to vancomycin	0.005	0.994	0.000
U84.9 Resistance to unspecified antimicrobial drugs	0.005	0.994	0.000
U84.8 Resistance to other specified antimicrobial drug	0.005	0.994	0.000
U84.7 Resistance to multiple antimicrobial drugs	0.005	0.994	0.000
U84.3 Resistance to tuberculostatic drug(s)	0.005	0.994	0.000
U84.2 Resistance to antiviral drug(s)	0.005	0.994	0.000
U84.1 Resistance to antifungal drug(s)	0.005	0.994	0.000
U84.0 Resistance to antiparasitic drug(s)	0.005	0.994	0.000
H60.0 Abscess of external ear	0.000	0.995	0.005
E30.9 Disorder of puberty, unspecified	0.005	0.995	0.000
E30.8 Other disorders of puberty	0.005	0.995	0.000
E30.1 Precocious puberty	0.005	0.995	0.000
E30.0 Delayed puberty	0.005	0.995	0.000
E32.9 Disease of thymus, unspecified	0.005	0.995	0.000
E32.8 Other diseases of thymus	0.005	0.995	0.000
E32.1 Abscess of thymus	0.005	0.995	0.000
E32.0 Persistent hyperplasia of thymus	0.005	0.995	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.005	0.995	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.005	0.995	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.005	0.995	0.000
E31.9 Polyglandular dysfunction, unspecified	0.005	0.995	0.000
E31.8 Other polyglandular dysfunction	0.005	0.995	0.000
E31.1 Polyglandular hyperfunction	0.005	0.995	0.000
E20.8 Other hypoparathyroidism	0.005	0.995	0.000
E20.1 Pseudohypoparathyroidism	0.005	0.995	0.000
E20.0 Idiopathic hypoparathyroidism	0.005	0.995	0.000
E84 Cystic fibrosis	0.005	0.995	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.005	0.995	0.000
E89.3 Postprocedural hypopituitarism	0.005	0.995	0.000
E31.0 Autoimmune polyglandular failure	0.005	0.995	0.000
E25.9 Adrenogenital disorder, unspecified	0.005	0.995	0.000
E25.8 Other adrenogenital disorders	0.005	0.995	0.000
E29 Testicular dysfunction	0.005	0.995	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.995	0.005
E77 Disorders of glycoprotein metabolism	0.005	0.995	0.000
E76 Disorders of glycosaminoglycan metabolism	0.005	0.995	0.000
E72 Other disorders of amino-acid metabolism	0.005	0.995	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.005	0.995	0.000
E70 Disorders of aromatic amino-acid metabolism	0.005	0.995	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.005	0.995	0.000
E20.9 Hypoparathyroidism, unspecified	0.005	0.995	0.000
E73 Lactose intolerance	0.005	0.995	0.000
E34.0 Carcinoid syndrome	0.005	0.995	0.000
E74 Other disorders of carbohydrate metabolism	0.005	0.995	0.000
H60.5 Acute otitis externa, non-infective	0.000	0.995	0.005
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.005	0.995	0.000
E79 Disorders of purine and pyrimidine metabolism	0.005	0.995	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.005	0.995	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.005	0.995	0.000
M54.57 Low back pain (Lumbosacral region)	0.000	0.995	0.005
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.005	0.995	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.005	0.995	0.000
E26.9 Hyperaldosteronism, unspecified	0.004	0.995	0.000
K76.8 Other specified diseases of liver	0.005	0.995	0.000
E34.5 Androgen resistance syndrome	0.004	0.995	0.000
E34.4 Constitutional tall stature	0.004	0.995	0.000
E34.3 Short stature, not elsewhere classified	0.004	0.995	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.004	0.995	0.000
E34.1 Other hypersecretion of intestinal hormones	0.004	0.995	0.000
E26.8 Other hyperaldosteronism	0.004	0.995	0.000
E26.1 Secondary hyperaldosteronism	0.004	0.995	0.000
E23.0 Hypopituitarism	0.004	0.996	0.000
E89.4 Postprocedural ovarian failure	0.004	0.996	0.000
E85 Amyloidosis	0.004	0.996	0.000
C44.5 Skin of trunk	0.000	0.996	0.004
E10.3 With ophthalmic complications	0.000	0.996	0.004
E84.9 Cystic fibrosis, unspecified	0.004	0.996	0.000
B91 Sequelae of poliomyelitis	0.000	0.996	0.004
E22 Hyperfunction of pituitary gland	0.004	0.996	0.000
E88 Other metabolic disorders	0.004	0.996	0.000
H60.2 Malignant otitis externa	0.000	0.996	0.004
E84.8 Cystic fibrosis with other manifestations	0.004	0.996	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.004	0.996	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.004	0.996	0.000
E34.8 Other specified endocrine disorders	0.004	0.996	0.000
E29.9 Testicular dysfunction, unspecified	0.004	0.996	0.000
E29.8 Other testicular dysfunction	0.004	0.996	0.000
E29.0 Testicular hyperfunction	0.004	0.996	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.004	0.996	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.004	0.996	0.000
E70.3 Albinism	0.004	0.996	0.000
E70.2 Disorders of tyrosine metabolism	0.004	0.996	0.000
E70.1 Other hyperphenylalaninaemias	0.004	0.996	0.000
E70.0 Classical phenylketonuria	0.004	0.996	0.000
E71.3 Disorders of fatty-acid metabolism	0.004	0.996	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.004	0.996	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.004	0.996	0.000
E71.0 Maple-syrup-urine disease	0.004	0.996	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.004	0.996	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.004	0.996	0.000
E72.5 Disorders of glycine metabolism	0.004	0.996	0.000
E72.4 Disorders of ornithine metabolism	0.004	0.996	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.004	0.996	0.000
E72.2 Disorders of urea cycle metabolism	0.004	0.996	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.004	0.996	0.000
E72.0 Disorders of amino-acid transport	0.004	0.996	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.004	0.996	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.004	0.996	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.004	0.996	0.000
E76.2 Other mucopolysaccharidoses	0.004	0.996	0.000
E76.1 Mucopolysaccharidosis, type II	0.004	0.996	0.000
E76.0 Mucopolysaccharidosis, type I	0.004	0.996	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.004	0.996	0.000
E77.8 Other disorders of glycoprotein metabolism	0.004	0.996	0.000
E77.1 Defects in glycoprotein degradation	0.004	0.996	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.004	0.996	0.000
M07.3 Other psoriatic arthropathies	0.004	0.996	0.000
E73.8 Other lactose intolerance	0.004	0.996	0.000
E73.1 Secondary lactase deficiency	0.004	0.996	0.000
E73.0 Congenital lactase deficiency	0.004	0.996	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.004	0.996	0.000
E21.2 Other hyperparathyroidism	0.004	0.996	0.000
E73.9 Lactose intolerance, unspecified	0.004	0.996	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.004	0.996	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.004	0.996	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.004	0.996	0.000
E74.2 Disorders of galactose metabolism	0.004	0.996	0.000
E74.1 Disorders of fructose metabolism	0.004	0.996	0.000
E74.0 Glycogen storage disease	0.004	0.996	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.004	0.996	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.004	0.996	0.000
E89.5 Postprocedural testicular hypofunction	0.004	0.996	0.000
E89.1 Postprocedural hypoinsulinaemia	0.004	0.996	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.004	0.996	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.004	0.996	0.000
E79.1 Lesch-Nyhan syndrome	0.004	0.996	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.004	0.996	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.004	0.996	0.000
E85.9 Amyloidosis, unspecified	0.004	0.996	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.004	0.996	0.000
E75.6 Lipid storage disorder, unspecified	0.003	0.996	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.003	0.996	0.000
E75.3 Sphingolipidosis, unspecified	0.003	0.996	0.000
E75.2 Other sphingolipidosis	0.003	0.996	0.000
E75.1 Other gangliosidosis	0.003	0.996	0.000
E75.0 GM2 gangliosidosis	0.003	0.996	0.000
E21.4 Other specified disorders of parathyroid gland	0.003	0.996	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.003	0.996	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.003	0.996	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.004	0.996	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.003	0.996	0.000
M07.38 Other psoriatic arthropathies (Other)	0.003	0.997	0.000
E85.8 Other amyloidosis	0.003	0.997	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.003	0.997	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.003	0.997	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.003	0.997	0.000
E88.9 Metabolic disorder, unspecified	0.003	0.997	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.003	0.997	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.003	0.997	0.000
E88.8 Other specified metabolic disorders	0.003	0.997	0.000
D69 Purpura and other haemorrhagic conditions	0.003	0.997	0.000
L08 Other local infections of skin and subcutaneous tissue	0.000	0.997	0.003
H60.8 Other otitis externa	0.001	0.997	0.003
E75.5 Other lipid storage disorders	0.003	0.997	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.997	0.003
E22.8 Other hyperfunction of pituitary gland	0.003	0.997	0.000
S82.10 Fracture of upper end of tibia (closed)	0.000	0.997	0.003
E21.3 Hyperparathyroidism, unspecified	0.003	0.997	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.003	0.997	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.003	0.997	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.003	0.997	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.003	0.997	0.000
E85.3 Secondary systemic amyloidosis	0.003	0.997	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.003	0.997	0.000
E88.3 Tumour lysis syndrome	0.003	0.997	0.000
D69.8 Other specified haemorrhagic conditions	0.003	0.997	0.000
R85.5 Abnormal microbiological findings	0.000	0.997	0.003
S61.8 Open wound of other parts of wrist and hand	0.000	0.997	0.003
D69.1 Qualitative platelet defects	0.003	0.997	0.000
E88.2 Lipomatosis, not elsewhere classified	0.003	0.997	0.000
N97.9 Female infertility, unspecified	0.003	0.997	0.000
E26.0 Primary hyperaldosteronism	0.002	0.997	0.001
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.003	0.997	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.003	0.997	0.000
D69.5 Secondary thrombocytopenia	0.003	0.997	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.003	0.997	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.000	0.997	0.003
I89.0 Lymphoedema, not elsewhere classified	0.000	0.997	0.003
S02.8 Fractures of other skull and facial bones	0.003	0.997	0.000
D69.9 Haemorrhagic condition, unspecified	0.003	0.997	0.000
L08.0 Pyoderma	0.000	0.997	0.003
E34.9 Endocrine disorder, unspecified	0.002	0.997	0.001
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.997	0.003
E10.4 With neurological complications	0.000	0.997	0.003
D69.4 Other primary thrombocytopenia	0.003	0.997	0.000
H65.3 Chronic mucoid otitis media	0.000	0.997	0.003
L08.1 Erythrasma	0.000	0.997	0.003
C49.3 Connective and soft tissue of thorax	0.000	0.997	0.003
R45.8 Other symptoms and signs involving emotional state	0.000	0.997	0.003
Chapter IV Endocrine, nutritional and metabolic diseases	0.003	0.997	0.000
E10.2 With renal complications	0.000	0.997	0.003
E85.4 Organ-limited amyloidosis	0.002	0.997	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.997	0.003
D69.3 Idiopathic thrombocytopenic purpura	0.003	0.997	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.002	0.997	0.000
E80.5 Crigler-Najjar syndrome	0.002	0.997	0.000
E80.3 Defects of catalase and peroxydase	0.002	0.997	0.000
E80.0 Hereditary erythropoietic porphyria	0.002	0.997	0.000
D69.2 Other nonthrombocytopenic purpura	0.002	0.997	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.997	0.003
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.997	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.997	0.003
E80.2 Other porphyria	0.002	0.998	0.000
S82.1 Fracture of upper end of tibia	0.000	0.998	0.002
I98.2 Oesophageal varices in diseases classified elsewhere	0.002	0.998	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
E80.1 Porphyria cutanea tarda	0.002	0.998	0.000
E80.6 Other disorders of bilirubin metabolism	0.002	0.998	0.000
E10.6 With other specified complications	0.000	0.998	0.002
E89.2 Postprocedural hypoparathyroidism	0.002	0.998	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.998	0.002
D69.0 Allergic purpura	0.002	0.998	0.000
S02.81 Fractures of other skull and facial bones (open)	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.002	0.998	0.001
S82.11 Fracture of upper end of tibia (open)	0.000	0.998	0.002
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.998	0.002
Z89.5 Acquired absence of leg at or below knee	0.000	0.998	0.002
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.998	0.002
E10.0 With coma	0.000	0.998	0.002
M54.9 Dorsalgia, unspecified	0.000	0.998	0.002
Z95 Presence of cardiac and vascular implants and grafts	0.002	0.998	0.000
E10.7 With multiple complications	0.000	0.998	0.002
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.002	0.998	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.998	0.002
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.998	0.002
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.002	0.998	0.000
K81.9 Cholecystitis, unspecified	0.000	0.998	0.002
E10.5 With peripheral circulatory complications	0.000	0.998	0.002
J15.2 Pneumonia due to staphylococcus	0.002	0.998	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.002	0.998	0.000
I89.1 Lymphangitis	0.000	0.998	0.002
R50.0 Fever with chills	0.000	0.998	0.002
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.998	0.002
G80.9 Infantile cerebral palsy, unspecified	0.000	0.998	0.002
Z43.6 Attention to other artificial openings of urinary tract	0.000	0.998	0.002
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.998	0.002
R86.7 Abnormal histological findings	0.002	0.998	0.000
S82.70 Multiple fractures of lower leg (closed)	0.000	0.998	0.002
E22.0 Acromegaly and pituitary gigantism	0.002	0.998	0.001
R86.9 Unspecified abnormal finding	0.002	0.998	0.000
E29.1 Testicular hypofunction	0.001	0.998	0.001
R86.6 Abnormal cytological findings	0.002	0.998	0.000
M07 Psoriatic and enteropathic arthropathies	0.002	0.998	0.000
E40-E46 Malnutrition	0.002	0.998	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.998	0.002
E10.8 With unspecified complications	0.000	0.998	0.002
R86 Abnormal findings in specimens from male genital organs	0.002	0.998	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.002	0.998	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.998	0.002
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.000	0.998	0.002
C49.9 Connective and soft tissue, unspecified	0.000	0.998	0.002
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.998	0.002
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.998	0.002
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
K75.9 Inflammatory liver disease, unspecified	0.000	0.998	0.002
H53.1 Subjective visual disturbances	0.002	0.998	0.000
L60.2 Onychogryphosis	0.002	0.998	0.000
C49.0 Connective and soft tissue of head, face and neck	0.000	0.998	0.002
E15 Nondiabetic hypoglycaemic coma	0.002	0.998	0.000
H60-H62 Diseases of external ear	0.000	0.998	0.002
C49.4 Connective and soft tissue of abdomen	0.000	0.998	0.002
S82.7 Multiple fractures of lower leg	0.000	0.998	0.002
Z89.4 Acquired absence of foot and ankle	0.000	0.998	0.002
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.998	0.002
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.998	0.002
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.000	0.998	0.002
H27.1 Dislocation of lens	0.002	0.998	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.000	0.998	0.002
E16 Other disorders of pancreatic internal secretion	0.002	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.998	0.000
M07.6 Other enteropathic arthropathies	0.002	0.998	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.998	0.002
E44 Protein-energy malnutrition of moderate and mild degree	0.002	0.998	0.000
E45 Retarded development following protein-energy malnutrition	0.002	0.998	0.000
E43 Unspecified severe protein-energy malnutrition	0.002	0.998	0.000
E42 Marasmic kwashiorkor	0.002	0.998	0.000
E41 Nutritional marasmus	0.002	0.998	0.000
E40 Kwashiorkor	0.002	0.998	0.000
G80 Infantile cerebral palsy	0.000	0.998	0.002
G80.2 Infantile hemiplegia	0.000	0.998	0.002
M07.5 Arthropathy in ulcerative colitis	0.002	0.998	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.002	0.998	0.000
M07.2 Psoriatic spondylitis	0.002	0.998	0.000
M07.1 Arthritis mutilans	0.002	0.998	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.002	0.998	0.000
R86.5 Abnormal microbiological findings	0.002	0.998	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.000	0.998	0.002
Z89 Acquired absence of limb	0.000	0.998	0.002
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
R86.8 Other abnormal findings	0.002	0.998	0.000
S61 Open wound of wrist and hand	0.000	0.998	0.002
M54.50 Low back pain (Multiple sites in spine)	0.000	0.998	0.002
R09.1 Pleurisy	0.000	0.998	0.002
R86.4 Abnormal immunological findings	0.002	0.998	0.000
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R86.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.998	0.000
R86.1 Abnormal level of hormones	0.002	0.998	0.000
R86.0 Abnormal level of enzymes	0.002	0.998	0.000
S82.6 Fracture of lateral malleolus	0.000	0.998	0.002
Y65.8 Other specified misadventures during surgical and medical care	0.000	0.998	0.002
Z89.9 Acquired absence of limb, unspecified	0.000	0.998	0.002
I78.1 Naevus, nonneoplastic	0.002	0.998	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.000	0.998	0.002
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.000	0.998	0.001
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
G80.0 Spastic cerebral palsy	0.000	0.998	0.001
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.998	0.001
S82.40 Fracture of fibula alone (closed)	0.000	0.998	0.002
S82.50 Fracture of medial malleolus (closed)	0.000	0.998	0.002
D04.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
S82.5 Fracture of medial malleolus	0.000	0.998	0.002
S82.4 Fracture of fibula alone	0.000	0.998	0.002
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.998	0.002
S82 Fracture of lower leg, including ankle	0.000	0.998	0.002
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.002	0.998	0.000
S82.71 Multiple fractures of lower leg (open)	0.000	0.998	0.001
E16.1 Other hypoglycaemia	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations