TreeWAS – Variant ID: rs74625856

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000
I20.9 Angina pectoris, unspecified	1.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	1.000	0.000
I25.2 Old myocardial infarction	1.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	1.000	0.000
Z95.5 Presence of coronary angioplasty implant and graft	1.000	0.000
Z95.1 Presence of aortocoronary bypass graft	1.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	1.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000
I20 Angina pectoris	1.000	0.000
Z95 Presence of cardiac and vascular implants and grafts	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
I25.9 Chronic ischaemic heart disease, unspecified	1.000	0.000
I21 Acute myocardial infarction	1.000	0.000
I30-I52 Other forms of heart disease	1.000	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000
I20.0 Unstable angina	1.000	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
E70-E90 Metabolic disorders	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.999	0.001
I21.1 Acute transmural myocardial infarction of inferior wall	0.997	0.003
I10-I15 Hypertensive diseases	0.997	0.003
E78.5 Hyperlipidaemia, unspecified	0.996	0.004
I10 Essential (primary) hypertension	0.995	0.005
Chapter II Neoplasms	0.995	0.005
J20-J22 Other acute lower respiratory infections	0.993	0.007
Z70-Z76 Persons encountering health services in other circumstances	0.992	0.008
E87 Other disorders of fluid, electrolyte and acid-base balance	0.989	0.011
J22 Unspecified acute lower respiratory infection	0.988	0.012
I35 Nonrheumatic aortic valve disorders	0.988	0.012
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.987	0.013
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.986	0.014
I21.9 Acute myocardial infarction, unspecified	0.984	0.016
Chapter XX External causes of morbidity and mortality	0.984	0.016
I51 Complications and ill-defined descriptions of heart disease	0.983	0.017
I22 Subsequent myocardial infarction	0.980	0.020
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.978	0.022
I74 Arterial embolism and thrombosis	0.976	0.024
E87.1 Hypo-osmolality and hyponatraemia	0.975	0.025
I60-I69 Cerebrovascular diseases	0.974	0.026
Z95.2 Presence of prosthetic heart valve	0.971	0.029
I21.4 Acute subendocardial myocardial infarction	0.971	0.029
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.969	0.031
C64-C68 Malignant neoplasms of urinary tract	0.957	0.043
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.957	0.043
I73 Other peripheral vascular diseases	0.956	0.044
I35.0 Aortic (valve) stenosis	0.955	0.045
R07 Pain in throat and chest	0.955	0.045
I34 Nonrheumatic mitral valve disorders	0.953	0.047
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.952	0.048
Z71.8 Other specified counselling	0.952	0.048
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.952	0.048
I77 Other disorders of arteries and arterioles	0.950	0.050
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.950	0.050
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.950	0.050
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.948	0.052
J30-J39 Other diseases of upper respiratory tract	0.946	0.054
I20.8 Other forms of angina pectoris	0.945	0.055
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.944	0.056
I51.7 Cardiomegaly	0.940	0.060
I22.9 Subsequent myocardial infarction of unspecified site	0.939	0.061
R07.3 Other chest pain	0.937	0.063
I71 Aortic aneurysm and dissection	0.936	0.064
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.935	0.065
I72 Other aneurysm	0.932	0.068
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.931	0.069
J95-J99 Other diseases of the respiratory system	0.929	0.071
Z95.0 Presence of cardiac pacemaker	0.928	0.072
R07.4 Chest pain, unspecified	0.926	0.074
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.926	0.074
Chapter VIII Diseases of the ear and mastoid process	0.919	0.081
Z71.3 Dietary counselling and surveillance	0.918	0.082
J09-J18 Influenza and pneumonia	0.916	0.084
M45-M49 Spondylopathies	0.914	0.086
Chapter XXII Codes for special purposes	0.912	0.088
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.908	0.092
M50-M54 Other dorsopathies	0.908	0.092
Z92 Personal history of medical treatment	0.907	0.093
Z98 Other postsurgical states	0.905	0.095
I77.1 Stricture of artery	0.900	0.100
I51.9 Heart disease, unspecified	0.899	0.101
M54 Dorsalgia	0.899	0.101
S90-S99 Injuries to the ankle and foot	0.896	0.104
M54.9 Dorsalgia, unspecified	0.894	0.106
M47 Spondylosis	0.891	0.109
M54.99 Dorsalgia, unspecified (Site unspecified)	0.888	0.112
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.888	0.112
Chapter I Certain infectious and parasitic diseases	0.888	0.112
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.887	0.113
R06 Abnormalities of breathing	0.887	0.113
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.886	0.114
C67 Malignant neoplasm of bladder	0.886	0.114
R44 Other symptoms and signs involving general sensations and perceptions	0.885	0.115
I42 Cardiomyopathy	0.884	0.116
I73.0 Raynaud's syndrome	0.884	0.116
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.883	0.117
I50 Heart failure	0.882	0.118
Z95.4 Presence of other heart-valve replacement	0.881	0.119
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.880	0.120
Z92.2 Personal history of long-term (current) use of other medicaments	0.879	0.121
T82.0 Mechanical complication of heart valve prosthesis	0.877	0.123
E78.2 Mixed hyperlipidaemia	0.876	0.124
C73 Malignant neoplasm of thyroid gland	0.876	0.124
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.875	0.125
I24 Other acute ischaemic heart diseases	0.875	0.125
I35.8 Other aortic valve disorders	0.872	0.128
J32 Chronic sinusitis	0.871	0.129
I34.0 Mitral (valve) insufficiency	0.869	0.131
M47.9 Spondylosis, unspecified	0.869	0.131
J98 Other respiratory disorders	0.866	0.134
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.862	0.138
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.862	0.138
I31 Other diseases of pericardium	0.860	0.140
I25.5 Ischaemic cardiomyopathy	0.858	0.142
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.858	0.142
Z71.1 Person with feared complaint in whom no diagnosis is made	0.857	0.143
I45 Other conduction disorders	0.856	0.144
C83 Diffuse non-Hodgkin's lymphoma	0.856	0.144
I51.6 Cardiovascular disease, unspecified	0.855	0.145
E65-E68 Obesity and other hyperalimentation	0.852	0.148
I35.2 Aortic (valve) stenosis with insufficiency	0.852	0.148
C64 Malignant neoplasm of kidney, except renal pelvis	0.851	0.149
T93 Sequelae of injuries of lower limb	0.848	0.151
I34.1 Mitral (valve) prolapse	0.846	0.154
I46 Cardiac arrest	0.846	0.154
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.845	0.155
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.839	0.161
S20-S29 Injuries to the thorax	0.839	0.161
C67.9 Bladder, unspecified	0.838	0.162
I72.4 Aneurysm of artery of lower extremity	0.833	0.167
J32.0 Chronic maxillary sinusitis	0.827	0.173
R07.0 Pain in throat	0.827	0.173
M47.96 Spondylosis, unspecified (Lumbar region)	0.826	0.174
S40-S49 Injuries to the shoulder and upper arm	0.825	0.175
I65.2 Occlusion and stenosis of carotid artery	0.825	0.175
E87.2 Acidosis	0.821	0.179
E78.8 Other disorders of lipoprotein metabolism	0.820	0.180
I22.1 Subsequent myocardial infarction of inferior wall	0.820	0.180
Y60-Y69 Misadventures to patients during surgical and medical care	0.819	0.181
I38 Endocarditis, valve unspecified	0.818	0.182
I33 Acute and subacute endocarditis	0.815	0.185
I25.0 Atherosclerotic cardiovascular disease, so described	0.815	0.185
B95-B98 Bacterial, viral and other infectious agents	0.813	0.187
Z97 Presence of other devices	0.813	0.187
Z72 Problems related to lifestyle	0.812	0.188
C71 Malignant neoplasm of brain	0.812	0.188
R07.2 Precordial pain	0.812	0.188
Y46 Antiepileptics and anti-Parkinsonism drugs	0.811	0.189
Z95.3 Presence of xenogenic heart valve	0.810	0.190
I22.8 Subsequent myocardial infarction of other sites	0.809	0.191
I05-I09 Chronic rheumatic heart diseases	0.809	0.191
I62 Other nontraumatic intracranial haemorrhage	0.808	0.192
I64 Stroke, not specified as haemorrhage or infarction	0.807	0.193
E87.7 Fluid overload	0.806	0.194
J98.1 Pulmonary collapse	0.806	0.194
D00-D09 In situ neoplasms	0.803	0.197
M54.2 Cervicalgia	0.803	0.197
R42 Dizziness and giddiness	0.803	0.197
R44.1 Visual hallucinations	0.803	0.197
R06.0 Dyspnoea	0.802	0.198
I74.5 Embolism and thrombosis of iliac artery	0.801	0.199
I72.0 Aneurysm of carotid artery	0.800	0.200
C81 Hodgkin's disease	0.799	0.201
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.797	0.203
I77.9 Disorder of arteries and arterioles, unspecified	0.796	0.204
Z92.3 Personal history of irradiation	0.795	0.205
Z98.8 Other specified postsurgical states	0.795	0.205
M70-M79 Other soft tissue disorders	0.795	0.205
I67 Other cerebrovascular diseases	0.794	0.206
I36 Nonrheumatic tricuspid valve disorders	0.792	0.208
Chapter VII Diseases of the eye and adnexa	0.791	0.209
H60-H62 Diseases of external ear	0.790	0.210
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.788	0.211
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.788	0.212
C90 Multiple myeloma and malignant plasma cell neoplasms	0.786	0.214
C40-C41 Malignant neoplasms of bone and articular cartilage	0.786	0.214
T82.1 Mechanical complication of cardiac electronic device	0.783	0.217
R47-R49 Symptoms and signs involving speech and voice	0.783	0.217
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.783	0.217
Z98.0 Intestinal bypass and anastomosis status	0.782	0.218
Z93 Artificial opening status	0.782	0.218
I46.0 Cardiac arrest with successful resuscitation	0.782	0.218
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.782	0.218
Y52 Agents primarily affecting the cardiovascular system	0.781	0.219
I60 Subarachnoid haemorrhage	0.780	0.220
I42.9 Cardiomyopathy, unspecified	0.780	0.220
I73.8 Other specified peripheral vascular diseases	0.779	0.221
H80-H83 Diseases of inner ear	0.777	0.223
I73.9 Peripheral vascular disease, unspecified	0.776	0.224
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.773	0.227
J39 Other diseases of upper respiratory tract	0.772	0.228
I50.0 Congestive heart failure	0.771	0.229
I21.3 Acute transmural myocardial infarction of unspecified site	0.770	0.230
I24.9 Acute ischaemic heart disease, unspecified	0.769	0.231
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.768	0.232
R41 Other symptoms and signs involving cognitive functions and awareness	0.766	0.234
T90 Sequelae of injuries of head	0.766	0.234
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.765	0.235
J35 Chronic diseases of tonsils and adenoids	0.762	0.237
I20.1 Angina pectoris with documented spasm	0.762	0.238
Y40 Systemic antibiotics	0.762	0.238
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.762	0.238
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.762	0.238
I63 Cerebral infarction	0.761	0.239
S90 Superficial injury of ankle and foot	0.761	0.239
T80 Complications following infusion, transfusion and therapeutic injection	0.760	0.240
I71.3 Abdominal aortic aneurysm, ruptured	0.760	0.240
X20-X29 Contact with venomous animals and plants	0.760	0.240
I21.2 Acute transmural myocardial infarction of other sites	0.760	0.240
Z72.0 Tobacco use	0.760	0.240
J90-J94 Other diseases of pleura	0.760	0.240
J15 Bacterial pneumonia, not elsewhere classified	0.760	0.240
J18 Pneumonia, organism unspecified	0.759	0.241
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.759	0.241
E78.4 Other hyperlipidaemia	0.759	0.241
J60-J70 Lung diseases due to external agents	0.758	0.242
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.758	0.242
J99 Respiratory disorders in diseases classified elsewhere	0.757	0.243
A30-A49 Other bacterial diseases	0.756	0.244
T82.3 Mechanical complication of other vascular grafts	0.756	0.244
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.755	0.244
T92 Sequelae of injuries of upper limb	0.754	0.246
T79-T79 Certain early complications of trauma	0.754	0.246
C04 Malignant neoplasm of floor of mouth	0.753	0.246
T86 Failure and rejection of transplanted organs and tissues	0.752	0.248
H65-H75 Diseases of middle ear and mastoid	0.751	0.249
E85 Amyloidosis	0.750	0.250
R06.8 Other and unspecified abnormalities of breathing	0.750	0.250
C83.3 Large cell (diffuse)	0.750	0.250
E87.6 Hypokalaemia	0.749	0.251
M60-M63 Disorders of muscles	0.748	0.251
C34 Malignant neoplasm of bronchus and lung	0.748	0.252
T87 Complications peculiar to reattachment and amputation	0.747	0.253
E66 Obesity	0.747	0.253
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.745	0.255
S92 Fracture of foot, except ankle	0.745	0.255
R44.0 Auditory hallucinations	0.744	0.256
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.744	0.256
Y45.1 Salicylates	0.743	0.257
J38.3 Other diseases of vocal cords	0.743	0.257
M80-M85 Disorders of bone density and structure	0.742	0.258
M86-M90 Other osteopathies	0.742	0.258
I42.6 Alcoholic cardiomyopathy	0.742	0.258
W50-W64 Exposure to animate mechanical forces	0.742	0.258
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.741	0.259
Q20-Q28 Congenital malformations of the circulatory system	0.741	0.259
M47.8 Other spondylosis	0.741	0.259
M54.22 Cervicalgia (Cervical region)	0.741	0.259
E73 Lactose intolerance	0.740	0.260
M47.94 Spondylosis, unspecified (Thoracic region)	0.740	0.260
X50-X57 Overexertion, travel and privation	0.739	0.261
R06.4 Hyperventilation	0.739	0.261
E20-E35 Disorders of other endocrine glands	0.738	0.262
Y00-Y09 Assault	0.734	0.266
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.734	0.266
S10-S19 Injuries to the neck	0.734	0.266
J32.4 Chronic pansinusitis	0.733	0.267
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.733	0.267
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.731	0.269
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.731	0.269
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.730	0.270
V10-V19 Pedal cyclist injured in transport accident	0.730	0.270
Z94 Transplanted organ and tissue status	0.729	0.271
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.729	0.271
J11 Influenza, virus not identified	0.729	0.271
I35.9 Aortic valve disorder, unspecified	0.729	0.271
X60-X84 Intentional self-harm	0.728	0.272
Y44 Agents primarily affecting blood constituents	0.728	0.272
I31.3 Pericardial effusion (noninflammatory)	0.728	0.272
X40-X49 Accidental poisoning by and exposure to noxious substances	0.726	0.273
J93 Pneumothorax	0.726	0.274
T66-T78 Other and unspecified effects of external causes	0.724	0.276
Z75 Problems related to medical facilities and other health care	0.723	0.277
Z76 Persons encountering health services in other circumstances	0.723	0.277
V40-V49 Car occupant injured in transport accident	0.722	0.278
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.721	0.279
J17 Pneumonia in diseases classified elsewhere	0.720	0.280
J20 Acute bronchitis	0.720	0.280
Chapter XI Diseases of the digestive system	0.719	0.281
T93.8 Sequelae of other specified injuries of lower limb	0.718	0.282
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.717	0.283
I11 Hypertensive heart disease	0.717	0.283
E78.6 Lipoprotein deficiency	0.717	0.283
E78.3 Hyperchylomicronaemia	0.717	0.283
E78.1 Pure hyperglyceridaemia	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.4 Coronary artery aneurysm	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I37 Pulmonary valve disorders	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
Z81 Family history of mental and behavioural disorders	0.717	0.283
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.717	0.283
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.717	0.283
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.717	0.283
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.717	0.283
Z82.2 Family history of deafness and hearing loss	0.717	0.283
Z82.1 Family history of blindness and visual loss	0.717	0.283
E84 Cystic fibrosis	0.717	0.283
E79 Disorders of purine and pyrimidine metabolism	0.717	0.283
E77 Disorders of glycoprotein metabolism	0.717	0.283
E76 Disorders of glycosaminoglycan metabolism	0.717	0.283
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.717	0.283
E74 Other disorders of carbohydrate metabolism	0.717	0.283
E72 Other disorders of amino-acid metabolism	0.717	0.283
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.717	0.283
E70 Disorders of aromatic amino-acid metabolism	0.717	0.283
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.717	0.283
C67.3 Anterior wall of bladder	0.716	0.284
I77.8 Other specified disorders of arteries and arterioles	0.716	0.284
V20-V29 Motorcycle rider injured in transport accident	0.716	0.284
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.715	0.285
V80-V89 Other land transport accidents	0.715	0.285
I15 Secondary hypertension	0.715	0.285
I13 Hypertensive heart and renal disease	0.715	0.285
H83 Other diseases of inner ear	0.714	0.286
R00 Abnormalities of heart beat	0.714	0.286
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.712	0.288
I30 Acute pericarditis	0.712	0.288
J21 Acute bronchiolitis	0.712	0.288
Y46.2 Hydantoin derivatives	0.712	0.288
Z84 Family history of other conditions	0.712	0.288
C71.9 Brain, unspecified	0.712	0.288
Z70 Counselling related to sexual attitude, behaviour and orientation	0.711	0.289
Y41 Other systemic anti-infectives and antiparasitics	0.711	0.289
K70-K77 Diseases of liver	0.711	0.289
I24.8 Other forms of acute ischaemic heart disease	0.710	0.290
R40 Somnolence, stupor and coma	0.709	0.291
E87.4 Mixed disorder of acid-base balance	0.709	0.291
T33-T35 Frostbite	0.708	0.292
T26-T28 Burns and corrosions confined to eye and internal organs	0.708	0.292
T20-T25 Burns and corrosions of external body surface, specified by site	0.708	0.292
T00-T07 Injuries involving multiple body regions	0.708	0.292
M54.4 Lumbago with sciatica	0.707	0.293
Z71.7 Human immunodeficiency virus [HIV] counselling	0.707	0.293
Z71.6 Tobacco abuse counselling	0.707	0.293
Z71.5 Drug abuse counselling and surveillance	0.707	0.293
Z71.4 Alcohol abuse counselling and surveillance	0.707	0.293
Z71.2 Person consulting for explanation of investigation findings	0.707	0.293
Z71.0 Person consulting on behalf of another person	0.707	0.293
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.707	0.293
C91 Lymphoid leukaemia	0.705	0.295
Y35-Y36 Legal intervention and operations of war	0.705	0.295
Y10-Y34 Event of undetermined intent	0.705	0.295
X85-X99 Assault	0.705	0.295
X58-X59 Accidental exposure to other and unspecified factors	0.705	0.295
X30-X39 Exposure to forces of nature	0.705	0.295
X10-X19 Contact with heat and hot substances	0.705	0.295
X00-X09 Exposure to smoke, fire and flames	0.705	0.295
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.705	0.295
W75-W84 Other accidental threats to breathing	0.705	0.295
W65-W74 Accidental drowning and submersion	0.705	0.295
V98-V99 Other and unspecified transport accidents	0.705	0.295
V95-V97 Air and space transport accidents	0.705	0.295
V90-V94 Water transport accidents	0.705	0.295
V70-V79 Bus occupant injured in transport accident	0.705	0.295
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.705	0.295
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.705	0.295
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.705	0.295
V01-V09 Pedestrian injured in transport accident	0.705	0.295
I08 Multiple valve diseases	0.705	0.295
I51.5 Myocardial degeneration	0.704	0.295
I51.4 Myocarditis, unspecified	0.704	0.295
I51.3 Intracardiac thrombosis, not elsewhere classified	0.704	0.295
I51.2 Rupture of papillary muscle, not elsewhere classified	0.704	0.295
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.704	0.295
I51.0 Cardiac septal defect, acquired	0.704	0.295
I61 Intracerebral haemorrhage	0.704	0.296
M91-M94 Chondropathies	0.704	0.296
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.703	0.297
J93.9 Pneumothorax, unspecified	0.703	0.297
I22.0 Subsequent myocardial infarction of anterior wall	0.702	0.298
I70 Atherosclerosis	0.702	0.298
E87.3 Alkalosis	0.701	0.298
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.701	0.298
C95 Leukaemia of unspecified cell type	0.701	0.298
C94 Other leukaemias of specified cell type	0.701	0.298
C93 Monocytic leukaemia	0.701	0.298
C88 Malignant immunoproliferative diseases	0.701	0.298
C86 Other specified types of T/NK-cell lymphoma	0.701	0.298
C84 Peripheral and cutaneous T-cell lymphomas	0.701	0.298
I74.9 Embolism and thrombosis of unspecified artery	0.700	0.300
I74.8 Embolism and thrombosis of other arteries	0.700	0.300
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.700	0.300
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.700	0.300
I74.0 Embolism and thrombosis of abdominal aorta	0.700	0.300
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.699	0.301
Z93.5 Cystostomy status	0.699	0.301
H10-H13 Disorders of conjunctiva	0.699	0.301
I68 Cerebrovascular disorders in diseases classified elsewhere	0.698	0.302
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.698	0.302
Q50-Q56 Congenital malformations of genital organs	0.698	0.302
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.698	0.302
J30 Vasomotor and allergic rhinitis	0.697	0.303
Y51 Drugs primarily affecting the autonomic nervous system	0.696	0.304
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.696	0.304
M54.94 Dorsalgia, unspecified (Thoracic region)	0.696	0.304
Y65 Other misadventures during surgical and medical care	0.696	0.304
I25.3 Aneurysm of heart	0.696	0.304
S20 Superficial injury of thorax	0.695	0.305
E66.8 Other obesity	0.694	0.306
E88 Other metabolic disorders	0.693	0.306
I50.9 Heart failure, unspecified	0.693	0.307
M77 Other enthesopathies	0.693	0.307
C67.5 Bladder neck	0.692	0.308
I45.1 Other and unspecified right bundle-branch block	0.691	0.309
I45.5 Other specified heart block	0.691	0.309
T85 Complications of other internal prosthetic devices, implants and grafts	0.691	0.309
C01 Malignant neoplasm of base of tongue	0.691	0.309
I78 Diseases of capillaries	0.691	0.309
M53 Other dorsopathies, not elsewhere classified	0.690	0.310
S91 Open wound of ankle and foot	0.690	0.310
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.689	0.310
R47 Speech disturbances, not elsewhere classified	0.688	0.312
I45.2 Bifascicular block	0.688	0.312
C71.3 Parietal lobe	0.687	0.313
C51-C58 Malignant neoplasms of female genital organs	0.686	0.314
C68 Malignant neoplasm of other and unspecified urinary organs	0.686	0.314
C66 Malignant neoplasm of ureter	0.686	0.314
C65 Malignant neoplasm of renal pelvis	0.686	0.314
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.686	0.314
I73.1 Thromboangiitis obliterans [Buerger]	0.685	0.315
R07.1 Chest pain on breathing	0.685	0.315
K90-K93 Other diseases of the digestive system	0.684	0.316
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.684	0.316
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.683	0.317
I34.8 Other nonrheumatic mitral valve disorders	0.683	0.317
I34.2 Nonrheumatic mitral (valve) stenosis	0.683	0.317
S27 Injury of other and unspecified intrathoracic organs	0.683	0.317
R95-R99 Ill-defined and unknown causes of mortality	0.683	0.317
Z98.2 Presence of cerebrospinal fluid drainage device	0.683	0.317
M00-M03 Infectious arthropathies	0.682	0.318
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.682	0.318
I33.0 Acute and subacute infective endocarditis	0.682	0.318
A80-A89 Viral infections of the central nervous system	0.681	0.318
I77.5 Necrosis of artery	0.681	0.319
I77.4 Coeliac artery compression syndrome	0.681	0.319
I77.3 Arterial fibromuscular dysplasia	0.681	0.319
I77.2 Rupture of artery	0.681	0.319
I77.0 Arteriovenous fistula, acquired	0.681	0.319
T93.0 Sequelae of open wound of lower limb	0.681	0.319
C92 Myeloid leukaemia	0.681	0.319
Y59 Other and unspecified vaccines and biological substances	0.681	0.319
Y58 Bacterial vaccines	0.681	0.319
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.681	0.319
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.681	0.319
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.681	0.319
Y53 Agents primarily affecting the gastro-intestinal system	0.681	0.319
Y50 Central nervous system stimulants, not elsewhere classified	0.681	0.319
Y49 Psychotropic drugs, not elsewhere classified	0.681	0.319
Y48 Anaesthetics and therapeutic gases	0.681	0.319
Y47 Sedatives, hypnotics and antianxiety drugs	0.681	0.319
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.681	0.319
J00-J06 Acute upper respiratory infections	0.681	0.319
M47.99 Spondylosis, unspecified (Site unspecified)	0.680	0.320
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.679	0.321
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.679	0.321
T82.4 Mechanical complication of vascular dialysis catheter	0.679	0.321
M79 Other soft tissue disorders, not elsewhere classified	0.679	0.321
J38.0 Paralysis of vocal cords and larynx	0.679	0.321
Z85 Personal history of malignant neoplasm	0.678	0.322
U80 Agent resistant to penicillin and related antibiotics	0.678	0.322
C02 Malignant neoplasm of other and unspecified parts of tongue	0.678	0.322
I31.9 Disease of pericardium, unspecified	0.677	0.323
S42 Fracture of shoulder and upper arm	0.676	0.324
I42.8 Other cardiomyopathies	0.676	0.324
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.675	0.325
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.675	0.325
E80 Disorders of porphyrin and bilirubin metabolism	0.674	0.326
I72.8 Aneurysm of other specified arteries	0.674	0.326
E40-E46 Malnutrition	0.674	0.326
R06.6 Hiccough	0.673	0.327
Z92.0 Personal history of contraception	0.672	0.328
H60 Otitis externa	0.672	0.328
Z97.5 Presence of (intra-uterine) contraceptive device	0.672	0.328
I71.8 Aortic aneurysm of unspecified site, ruptured	0.671	0.329
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.671	0.329
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.671	0.329
I71.1 Thoracic aortic aneurysm, ruptured	0.671	0.329
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.671	0.329
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.671	0.329
C81.9 Hodgkin's disease, unspecified	0.671	0.329
T98 Sequelae of other and unspecified effects of external causes	0.670	0.330
T95 Sequelae of burns, corrosions and frostbite	0.670	0.330
T94 Sequelae of injuries involving multiple and unspecified body regions	0.670	0.330
T91 Sequelae of injuries of neck and trunk	0.670	0.330

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations