TreeWAS – Variant ID: rs1529729

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	0.989	0.011	0.000
I20-I25 Ischaemic heart diseases	0.981	0.019	0.000
I20 Angina pectoris	0.976	0.024	0.000
I25.2 Old myocardial infarction	0.969	0.031	0.000
I20.0 Unstable angina	0.961	0.039	0.000
I20.9 Angina pectoris, unspecified	0.929	0.071	0.000
I24 Other acute ischaemic heart diseases	0.894	0.106	0.000
I20.1 Angina pectoris with documented spasm	0.863	0.137	0.000
I23 Certain current complications following acute myocardial infarction	0.831	0.169	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.830	0.170	0.000
I25.3 Aneurysm of heart	0.809	0.191	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.806	0.194	0.000
I25.6 Silent myocardial ischaemia	0.748	0.252	0.000
I23.8 Other current complications following acute myocardial infarction	0.723	0.277	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.662	0.338	0.000
I22 Subsequent myocardial infarction	0.651	0.349	0.000
I24.1 Dressler's syndrome	0.616	0.384	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.601	0.399	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.596	0.404	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.596	0.404	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.596	0.404	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.596	0.404	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.596	0.404	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.596	0.404	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.596	0.404	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.496	0.504	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.464	0.536	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.455	0.545	0.000
I21 Acute myocardial infarction	0.445	0.555	0.000
E78.5 Hyperlipidaemia, unspecified	0.441	0.559	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.436	0.564	0.000
I22.8 Subsequent myocardial infarction of other sites	0.412	0.588	0.000
I21.9 Acute myocardial infarction, unspecified	0.411	0.589	0.000
I25.5 Ischaemic cardiomyopathy	0.376	0.624	0.000
E78.1 Pure hyperglyceridaemia	0.375	0.625	0.000
I25.4 Coronary artery aneurysm	0.349	0.650	0.001
E78.3 Hyperchylomicronaemia	0.344	0.656	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.319	0.681	0.000
E78.6 Lipoprotein deficiency	0.312	0.688	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.306	0.694	0.000
E78.4 Other hyperlipidaemia	0.290	0.710	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.272	0.728	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.255	0.745	0.000
I24.8 Other forms of acute ischaemic heart disease	0.248	0.752	0.000
E78.8 Other disorders of lipoprotein metabolism	0.245	0.754	0.000
E78.2 Mixed hyperlipidaemia	0.184	0.816	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.183	0.817	0.000
I21.4 Acute subendocardial myocardial infarction	0.158	0.842	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.156	0.844	0.000
I20.8 Other forms of angina pectoris	0.142	0.858	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.112	0.888	0.000
I73.9 Peripheral vascular disease, unspecified	0.111	0.889	0.000
I73 Other peripheral vascular diseases	0.103	0.897	0.000
I71 Aortic aneurysm and dissection	0.101	0.899	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.100	0.900	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.099	0.901	0.000
Z82.1 Family history of blindness and visual loss	0.099	0.901	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.097	0.903	0.000
I71.0 Dissection of aorta [any part]	0.094	0.906	0.000
Chapter IX Diseases of the circulatory system	0.093	0.907	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.092	0.908	0.000
I74 Arterial embolism and thrombosis	0.091	0.909	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.090	0.910	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.088	0.912	0.000
Z82.2 Family history of deafness and hearing loss	0.086	0.914	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.085	0.915	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.084	0.916	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.083	0.917	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.081	0.919	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.080	0.919	0.000
I74.5 Embolism and thrombosis of iliac artery	0.080	0.920	0.000
I73.8 Other specified peripheral vascular diseases	0.079	0.921	0.000
C18 Malignant neoplasm of colon	0.079	0.921	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.078	0.921	0.001
C18.3 Hepatic flexure	0.078	0.922	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.077	0.923	0.000
C18.9 Colon, unspecified	0.077	0.923	0.000
C18.2 Ascending colon	0.076	0.924	0.000
C18.7 Sigmoid colon	0.074	0.926	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.073	0.927	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.073	0.927	0.000
I00-I02 Acute rheumatic fever	0.072	0.928	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.071	0.929	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.071	0.929	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.069	0.931	0.000
C18.1 Appendix	0.068	0.932	0.000
I74.8 Embolism and thrombosis of other arteries	0.068	0.932	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.068	0.932	0.000
I78 Diseases of capillaries	0.065	0.935	0.000
I05-I09 Chronic rheumatic heart diseases	0.061	0.939	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.060	0.940	0.000
C18.5 Splenic flexure	0.059	0.941	0.000
I00 Rheumatic fever without mention of heart involvement	0.057	0.943	0.000
I70 Atherosclerosis	0.056	0.944	0.000
I08 Multiple valve diseases	0.055	0.945	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.054	0.946	0.000
I02 Rheumatic chorea	0.052	0.948	0.000
I01 Rheumatic fever with heart involvement	0.052	0.948	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.051	0.949	0.000
C18.8 Overlapping lesion of colon	0.050	0.950	0.000
I78.8 Other diseases of capillaries	0.049	0.950	0.000
C18.6 Descending colon	0.049	0.951	0.000
I06 Rheumatic aortic valve diseases	0.048	0.952	0.000
I08.9 Multiple valve disease, unspecified	0.047	0.953	0.000
I78.9 Disease of capillaries, unspecified	0.046	0.953	0.000
I70.1 Atherosclerosis of renal artery	0.046	0.954	0.000
C18.4 Transverse colon	0.046	0.954	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.043	0.957	0.000
I79.1 Aortitis in diseases classified elsewhere	0.043	0.957	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.043	0.957	0.000
I86.1 Scrotal varices	0.043	0.957	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.043	0.957	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.042	0.958	0.000
I78.1 Naevus, nonneoplastic	0.042	0.958	0.000
I70.8 Atherosclerosis of other arteries	0.041	0.959	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.040	0.959	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.040	0.960	0.000
I86 Varicose veins of other sites	0.039	0.961	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.039	0.961	0.000
I77 Other disorders of arteries and arterioles	0.038	0.962	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.038	0.962	0.000
I07 Rheumatic tricuspid valve diseases	0.038	0.962	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.038	0.962	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.037	0.963	0.000
I01.8 Other acute rheumatic heart disease	0.037	0.963	0.000
I01.2 Acute rheumatic myocarditis	0.037	0.963	0.000
I01.1 Acute rheumatic endocarditis	0.037	0.963	0.000
I01.0 Acute rheumatic pericarditis	0.037	0.963	0.000
I02.9 Rheumatic chorea without heart involvement	0.037	0.963	0.000
I02.0 Rheumatic chorea with heart involvement	0.037	0.963	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.037	0.963	0.000
I51.9 Heart disease, unspecified	0.036	0.964	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.036	0.964	0.000
I09 Other rheumatic heart diseases	0.036	0.964	0.000
I70.9 Generalised and unspecified atherosclerosis	0.035	0.964	0.000
I70.0 Atherosclerosis of aorta	0.036	0.964	0.000
I08.8 Other multiple valve diseases	0.036	0.964	0.000
I06.0 Rheumatic aortic stenosis	0.035	0.965	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.035	0.965	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.034	0.966	0.000
I06.8 Other rheumatic aortic valve diseases	0.034	0.966	0.000
I77.2 Rupture of artery	0.034	0.966	0.000
Z82.3 Family history of stroke	0.033	0.967	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.033	0.967	0.000
I86.8 Varicose veins of other specified sites	0.033	0.967	0.000
I06.1 Rheumatic aortic insufficiency	0.032	0.968	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.032	0.968	0.000
I82 Other venous embolism and thrombosis	0.032	0.968	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.031	0.969	0.000
I86.2 Pelvic varices	0.031	0.969	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.030	0.970	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.030	0.970	0.000
I72 Other aneurysm	0.030	0.970	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.030	0.970	0.000
I86.4 Gastric varices	0.029	0.971	0.000
C18.0 Caecum	0.029	0.971	0.000
I86.0 Sublingual varices	0.028	0.972	0.000
I77.3 Arterial fibromuscular dysplasia	0.028	0.972	0.000
I77.5 Necrosis of artery	0.028	0.972	0.000
I77.4 Coeliac artery compression syndrome	0.028	0.972	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.027	0.972	0.000
I07.9 Tricuspid valve disease, unspecified	0.027	0.973	0.000
I07.8 Other tricuspid valve diseases	0.027	0.973	0.000
I07.2 Tricuspid stenosis with insufficiency	0.027	0.973	0.000
I07.0 Tricuspid stenosis	0.027	0.973	0.000
I09.8 Other specified rheumatic heart diseases	0.026	0.974	0.000
I09.2 Chronic rheumatic pericarditis	0.026	0.974	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.026	0.974	0.000
I09.0 Rheumatic myocarditis	0.026	0.974	0.000
I77.0 Arteriovenous fistula, acquired	0.026	0.974	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.026	0.974	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.026	0.974	0.000
I86.3 Vulval varices	0.025	0.974	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.025	0.975	0.000
I10-I15 Hypertensive diseases	0.024	0.976	0.000
I28 Other diseases of pulmonary vessels	0.024	0.976	0.000
I87 Other disorders of veins	0.023	0.977	0.000
I05 Rheumatic mitral valve diseases	0.023	0.977	0.000
I77.1 Stricture of artery	0.023	0.977	0.000
I08.0 Disorders of both mitral and aortic valves	0.023	0.977	0.000
I82.1 Thrombophlebitis migrans	0.023	0.977	0.000
I72.9 Aneurysm of unspecified site	0.023	0.977	0.000
I82.3 Embolism and thrombosis of renal vein	0.023	0.977	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.023	0.977	0.000
I73.0 Raynaud's syndrome	0.023	0.977	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.022	0.977	0.000
I82.0 Budd-Chiari syndrome	0.022	0.978	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.022	0.978	0.000
I97.0 Postcardiotomy syndrome	0.022	0.978	0.000
I99 Other and unspecified disorders of circulatory system	0.022	0.978	0.000
I97.1 Other functional disturbances following cardiac surgery	0.022	0.978	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.022	0.978	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.022	0.978	0.000
I72.1 Aneurysm of artery of upper extremity	0.022	0.978	0.000
I77.8 Other specified disorders of arteries and arterioles	0.021	0.979	0.000
I95 Hypotension	0.021	0.979	0.000
I07.1 Tricuspid insufficiency	0.021	0.979	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.021	0.979	0.000
I87.8 Other specified disorders of veins	0.021	0.979	0.000
I82.2 Embolism and thrombosis of vena cava	0.021	0.979	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.021	0.979	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.020	0.980	0.000
I95.2 Hypotension due to drugs	0.020	0.980	0.000
I88 Nonspecific lymphadenitis	0.020	0.980	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.020	0.980	0.000
I82.8 Embolism and thrombosis of other specified veins	0.020	0.980	0.000
I72.2 Aneurysm of renal artery	0.020	0.980	0.000
I72.4 Aneurysm of artery of lower extremity	0.019	0.981	0.000
I81 Portal vein thrombosis	0.019	0.981	0.000
I72.0 Aneurysm of carotid artery	0.018	0.982	0.000
I15 Secondary hypertension	0.018	0.982	0.000
I09.9 Rheumatic heart disease, unspecified	0.018	0.982	0.000
I28.8 Other specified diseases of pulmonary vessels	0.018	0.982	0.000
I05.2 Mitral stenosis with insufficiency	0.018	0.982	0.000
I13 Hypertensive heart and renal disease	0.017	0.982	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.017	0.983	0.000
I28.1 Aneurysm of pulmonary artery	0.017	0.983	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.017	0.983	0.000
I87.0 Postphlebitic syndrome	0.017	0.983	0.000
I05.8 Other mitral valve diseases	0.016	0.983	0.000
I26 Pulmonary embolism	0.016	0.984	0.000
I11 Hypertensive heart disease	0.015	0.984	0.000
I15.9 Seconday hypertension, unspecified	0.015	0.984	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.015	0.985	0.000
I72.3 Aneurysm of iliac artery	0.015	0.985	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.015	0.985	0.000
I15.0 Renovascular hypertension	0.015	0.985	0.000
I95.0 Idiopathic hypotension	0.015	0.985	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.014	0.985	0.001
I87.9 Disorder of vein, unspecified	0.014	0.985	0.000
I95.8 Other hypotension	0.014	0.985	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.014	0.985	0.000
I05.0 Mitral stenosis	0.014	0.986	0.000
I83 Varicose veins of lower extremities	0.014	0.986	0.000
I88.8 Other nonspecific lymphadenitis	0.014	0.986	0.000
I15.2 Hypertension secondary to endocrine disorders	0.013	0.987	0.000
I15.8 Other secondary hypertension	0.013	0.987	0.000
I85 Oesophageal varices	0.013	0.987	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.013	0.987	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.013	0.987	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.013	0.987	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.013	0.987	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.013	0.987	0.000
I51 Complications and ill-defined descriptions of heart disease	0.013	0.987	0.000
I87.1 Compression of vein	0.012	0.987	0.000
I72.8 Aneurysm of other specified arteries	0.012	0.987	0.000
I05.1 Rheumatic mitral insufficiency	0.012	0.988	0.000
I95.1 Orthostatic hypotension	0.012	0.988	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.012	0.988	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.011	0.989	0.000
I51.6 Cardiovascular disease, unspecified	0.011	0.989	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.011	0.989	0.000
I12 Hypertensive renal disease	0.011	0.989	0.000
I05.9 Mitral valve disease, unspecified	0.011	0.989	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.010	0.989	0.001
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.010	0.989	0.001
I98.0 Cardiovascular syphilis	0.010	0.989	0.001
I88.9 Nonspecific lymphadenitis, unspecified	0.010	0.989	0.000
I51.5 Myocardial degeneration	0.010	0.989	0.000
I15.1 Hypertension secondary to other renal disorders	0.010	0.989	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.010	0.990	0.000
I51.4 Myocarditis, unspecified	0.010	0.990	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.009	0.991	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.008	0.991	0.001
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.009	0.991	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.009	0.991	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.008	0.992	0.000
E27.8 Other specified disorders of adrenal gland	0.008	0.992	0.000
I89.0 Lymphoedema, not elsewhere classified	0.008	0.992	0.000
I77.6 Arteritis, unspecified	0.008	0.992	0.000
E34 Other endocrine disorders	0.007	0.993	0.000
I51.0 Cardiac septal defect, acquired	0.007	0.993	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.007	0.993	0.000
O75.8 Other specified complications of labour and delivery	0.007	0.993	0.000
I12.9 Hypertensive renal disease without renal failure	0.007	0.993	0.000
E34.8 Other specified endocrine disorders	0.007	0.993	0.000
I85.0 Oesophageal varices with bleeding	0.007	0.993	0.000
E27 Other disorders of adrenal gland	0.007	0.993	0.000
I89.1 Lymphangitis	0.007	0.993	0.000
E34.9 Endocrine disorder, unspecified	0.007	0.993	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.006	0.993	0.000
I35.0 Aortic (valve) stenosis	0.006	0.994	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.006	0.994	0.000
E34.0 Carcinoid syndrome	0.006	0.994	0.000
E34.3 Short stature, not elsewhere classified	0.006	0.994	0.000
E20-E35 Disorders of other endocrine glands	0.006	0.994	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.006	0.994	0.000
E23 Hypofunction and other disorders of pituitary gland	0.006	0.994	0.000
E27.1 Primary adrenocortical insufficiency	0.006	0.994	0.000
G95.1 Vascular myelopathies	0.006	0.994	0.000
E23.0 Hypopituitarism	0.006	0.994	0.000
G95.9 Disease of spinal cord, unspecified	0.006	0.994	0.000
E34.5 Androgen resistance syndrome	0.005	0.994	0.000
E34.4 Constitutional tall stature	0.005	0.994	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.005	0.994	0.000
E34.1 Other hypersecretion of intestinal hormones	0.005	0.994	0.000
L40.5 Arthropathic psoriasis	0.005	0.995	0.000
E27.9 Disorder of adrenal gland, unspecified	0.005	0.995	0.000
I35.8 Other aortic valve disorders	0.005	0.995	0.000
G95 Other diseases of spinal cord	0.005	0.995	0.000
E27.5 Adrenomedullary hyperfunction	0.005	0.995	0.000
E27.0 Other adrenocortical overactivity	0.005	0.995	0.000
E24 Cushing's syndrome	0.005	0.995	0.000
I35 Nonrheumatic aortic valve disorders	0.005	0.995	0.000
E23.2 Diabetes insipidus	0.005	0.995	0.000
I51.7 Cardiomegaly	0.005	0.995	0.000
E20 Hypoparathyroidism	0.005	0.995	0.000
G95.2 Cord compression, unspecified	0.005	0.995	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.005	0.995	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.005	0.995	0.000
I30-I52 Other forms of heart disease	0.005	0.995	0.000
C90.2 Plasmacytoma, extramedullary	0.000	0.995	0.005
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.005	0.995	0.000
E26 Hyperaldosteronism	0.005	0.995	0.000
E22 Hyperfunction of pituitary gland	0.005	0.995	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.005	0.995	0.000
E32 Diseases of thymus	0.005	0.995	0.000
E30 Disorders of puberty, not elsewhere classified	0.005	0.995	0.000
L40.0 Psoriasis vulgaris	0.005	0.995	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.004	0.995	0.000
E21.0 Primary hyperparathyroidism	0.005	0.995	0.000
E23.6 Other disorders of pituitary gland	0.005	0.995	0.000
E25 Adrenogenital disorders	0.004	0.995	0.000
E31 Polyglandular dysfunction	0.004	0.995	0.000
L40 Psoriasis	0.005	0.995	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.004	0.995	0.000
E23.1 Drug-induced hypopituitarism	0.004	0.995	0.000
O63.0 Prolonged first stage (of labour)	0.000	0.995	0.005
M48.02 Spinal stenosis (Cervical region)	0.000	0.995	0.005
E27.4 Other and unspecified adrenocortical insufficiency	0.004	0.996	0.000
Z34.8 Supervision of other normal pregnancy	0.004	0.996	0.000
I35.9 Aortic valve disorder, unspecified	0.004	0.996	0.000
I38 Endocarditis, valve unspecified	0.004	0.996	0.000
E24.8 Other Cushing's syndrome	0.004	0.996	0.000
M48.06 Spinal stenosis (Lumbar region)	0.000	0.996	0.004
E20.9 Hypoparathyroidism, unspecified	0.004	0.996	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.004	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.004	0.996	0.000
E27.2 Addisonian crisis	0.004	0.996	0.000
E24.2 Drug-induced Cushing's syndrome	0.004	0.996	0.000
L42 Pityriasis rosea	0.004	0.996	0.000
I85.9 Oesophageal varices without bleeding	0.004	0.996	0.000
I27 Other pulmonary heart diseases	0.004	0.996	0.000
I33 Acute and subacute endocarditis	0.004	0.996	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.004	0.996	0.000
E24.3 Ectopic ACTH syndrome	0.004	0.996	0.000
E24.1 Nelson's syndrome	0.004	0.996	0.000
E22.1 Hyperprolactinaemia	0.004	0.996	0.000
E24.0 Pituitary-dependent Cushing's disease	0.004	0.996	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.004	0.996	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.004	0.996	0.000
E21.2 Other hyperparathyroidism	0.004	0.996	0.000
E20.8 Other hypoparathyroidism	0.004	0.996	0.000
E20.1 Pseudohypoparathyroidism	0.004	0.996	0.000
E20.0 Idiopathic hypoparathyroidism	0.004	0.996	0.000
E26.9 Hyperaldosteronism, unspecified	0.004	0.996	0.000
L40.4 Guttate psoriasis	0.004	0.996	0.000
G95.0 Syringomyelia and syringobulbia	0.004	0.996	0.000
I52 Other heart disorders in diseases classified elsewhere	0.004	0.996	0.000
I48 Atrial fibrillation and flutter	0.004	0.996	0.000
I41 Myocarditis in diseases classified elsewhere	0.004	0.996	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.004	0.996	0.000
I32 Pericarditis in diseases classified elsewhere	0.004	0.996	0.000
E21.4 Other specified disorders of parathyroid gland	0.004	0.996	0.000
L40-L45 Papulosquamous disorders	0.004	0.996	0.000
E22.8 Other hyperfunction of pituitary gland	0.004	0.996	0.000
E26.8 Other hyperaldosteronism	0.004	0.996	0.000
E26.1 Secondary hyperaldosteronism	0.004	0.996	0.000
E30.9 Disorder of puberty, unspecified	0.003	0.996	0.000
E30.8 Other disorders of puberty	0.003	0.996	0.000
E30.1 Precocious puberty	0.003	0.996	0.000
E30.0 Delayed puberty	0.003	0.996	0.000
E32.9 Disease of thymus, unspecified	0.003	0.996	0.000
E32.8 Other diseases of thymus	0.003	0.996	0.000
E32.1 Abscess of thymus	0.003	0.996	0.000
E32.0 Persistent hyperplasia of thymus	0.003	0.996	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.003	0.996	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.003	0.996	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.003	0.996	0.000
L40.8 Other psoriasis	0.004	0.996	0.000
Z95.1 Presence of aortocoronary bypass graft	0.004	0.996	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.996	0.004
E22.0 Acromegaly and pituitary gigantism	0.004	0.996	0.000
E29 Testicular dysfunction	0.004	0.996	0.000
E23.7 Disorder of pituitary gland, unspecified	0.003	0.996	0.000
E25.9 Adrenogenital disorder, unspecified	0.003	0.996	0.000
E25.8 Other adrenogenital disorders	0.003	0.996	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.004	0.996	0.000
I37 Pulmonary valve disorders	0.004	0.996	0.000
E31.9 Polyglandular dysfunction, unspecified	0.003	0.996	0.000
E31.8 Other polyglandular dysfunction	0.003	0.996	0.000
E31.1 Polyglandular hyperfunction	0.003	0.996	0.000
L40.2 Acrodermatitis continua	0.003	0.996	0.000
M48.0 Spinal stenosis	0.000	0.996	0.004
T81.8 Other complications of procedures, not elsewhere classified	0.004	0.996	0.000
I33.0 Acute and subacute infective endocarditis	0.003	0.996	0.000
E26.0 Primary hyperaldosteronism	0.003	0.996	0.000
L40.3 Pustulosis palmaris et plantaris	0.003	0.996	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.997	0.003
I51.8 Other ill-defined heart diseases	0.003	0.997	0.000
I40 Acute myocarditis	0.003	0.997	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.997	0.000
G95.8 Other specified diseases of spinal cord	0.003	0.997	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.003	0.997	0.000
C71.9 Brain, unspecified	0.000	0.997	0.003
E31.0 Autoimmune polyglandular failure	0.003	0.997	0.000
I30 Acute pericarditis	0.003	0.997	0.000
M07.3 Other psoriatic arthropathies	0.003	0.997	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.003	0.997	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.003	0.997	0.000
L43 Lichen planus	0.003	0.997	0.000
D12.8 Rectum	0.003	0.997	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.002	0.997	0.002
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.997	0.003
H61.2 Impacted cerumen	0.000	0.997	0.003
I12.0 Hypertensive renal disease with renal failure	0.003	0.997	0.000
I27.1 Kyphoscoliotic heart disease	0.003	0.997	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.997	0.003
J03.9 Acute tonsillitis, unspecified	0.000	0.997	0.003
I46 Cardiac arrest	0.003	0.997	0.000
R49.0 Dysphonia	0.003	0.997	0.000
H92.0 Otalgia	0.000	0.997	0.003
L40.1 Generalised pustular psoriasis	0.003	0.997	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.003	0.997	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.000	0.997	0.003
I80 Phlebitis and thrombophlebitis	0.003	0.997	0.000
I36 Nonrheumatic tricuspid valve disorders	0.003	0.997	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.003	0.997	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.003	0.997	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.003	0.997	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.003	0.997	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.003	0.997	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.003	0.997	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.003	0.997	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.003	0.997	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.003	0.997	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.003	0.997	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.003	0.997	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.003	0.997	0.000
I48.4 Atypical atrial flutter	0.003	0.997	0.000
I48.3 Typical atrial flutter	0.003	0.997	0.000
I48.2 Chronic atrial fibrillation	0.003	0.997	0.000
I48.1 Persistent atrial fibrillation	0.003	0.997	0.000
I48.0 Paroxysmal atrial fibrillation	0.003	0.997	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.003	0.997	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.003	0.997	0.000
L44 Other papulosquamous disorders	0.003	0.997	0.000
I33.9 Acute endocarditis, unspecified	0.003	0.997	0.000
I37.0 Pulmonary valve stenosis	0.003	0.997	0.000
Y04.8 Other specified place	0.000	0.997	0.003
L41 Parapsoriasis	0.003	0.997	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.003	0.997	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.003	0.997	0.000
E29.9 Testicular dysfunction, unspecified	0.003	0.997	0.000
E29.8 Other testicular dysfunction	0.003	0.997	0.000
E29.0 Testicular hyperfunction	0.003	0.997	0.000
I30.8 Other forms of acute pericarditis	0.003	0.997	0.000
I46.9 Cardiac arrest, unspecified	0.003	0.997	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.003	0.997	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.003	0.997	0.000
I37.9 Pulmonary valve disorder, unspecified	0.003	0.997	0.000
I37.8 Other pulmonary valve disorders	0.003	0.997	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.003	0.997	0.000
O73.0 Retained placenta, without haemorrhage	0.000	0.997	0.003
T81.4 Infection following a procedure, not elsewhere classified	0.003	0.997	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.997	0.003
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.997	0.003
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.997	0.003
C90.3 Solitary plasmacytoma	0.000	0.997	0.003
L43.9 Lichen planus, unspecified	0.003	0.997	0.000
I42 Cardiomyopathy	0.003	0.997	0.000
C90.0 Multiple myeloma	0.000	0.997	0.003
C90.1 Plasma cell leukaemia	0.000	0.997	0.003
T93.1 Sequelae of fracture of femur	0.000	0.997	0.003
I40.8 Other acute myocarditis	0.002	0.997	0.000
I40.1 Isolated myocarditis	0.002	0.997	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.000	0.997	0.003
I42.8 Other cardiomyopathies	0.003	0.997	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.002	0.997	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.002	0.997	0.000
T93 Sequelae of injuries of lower limb	0.000	0.997	0.003
E28 Ovarian dysfunction	0.002	0.997	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.003	0.997	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.997	0.003
M07.38 Other psoriatic arthropathies (Other)	0.003	0.997	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.003	0.997	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.003	0.997	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.997	0.003
L43.8 Other lichen planus	0.003	0.997	0.000
T93.0 Sequelae of open wound of lower limb	0.000	0.997	0.003
R21 Rash and other nonspecific skin eruption	0.003	0.997	0.000
S82.00 Fracture of patella (closed)	0.000	0.997	0.003
L43.3 Subacute (active) lichen planus	0.002	0.997	0.000
L43.2 Lichenoid drug reaction	0.002	0.997	0.000
L43.1 Bullous lichen planus	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations