TreeWAS – Variant ID: rs412522

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20 Angina pectoris	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I20.9 Angina pectoris, unspecified	1.000	0.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	1.000	0.000	0.000
I25.9 Chronic ischaemic heart disease, unspecified	1.000	0.000	0.000
I25.2 Old myocardial infarction	1.000	0.000	0.000
I20.0 Unstable angina	0.995	0.005	0.000
I22 Subsequent myocardial infarction	0.965	0.035	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.925	0.075	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.921	0.079	0.000
E78.0 Pure hypercholesterolaemia	0.910	0.090	0.000
I21 Acute myocardial infarction	0.903	0.097	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.893	0.107	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.893	0.107	0.000
Z95.1 Presence of aortocoronary bypass graft	0.888	0.112	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.887	0.113	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.840	0.160	0.000
Z95.0 Presence of cardiac pacemaker	0.822	0.178	0.000
I25.4 Coronary artery aneurysm	0.803	0.197	0.000
I22.8 Subsequent myocardial infarction of other sites	0.767	0.233	0.000
Z95.2 Presence of prosthetic heart valve	0.747	0.253	0.000
I24 Other acute ischaemic heart diseases	0.728	0.272	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.721	0.279	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
Z95.3 Presence of xenogenic heart valve	0.716	0.284	0.000
I23 Certain current complications following acute myocardial infarction	0.687	0.313	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.655	0.345	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.647	0.352	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.638	0.362	0.000
I25.3 Aneurysm of heart	0.624	0.376	0.000
I20.8 Other forms of angina pectoris	0.597	0.403	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.590	0.410	0.000
I21.9 Acute myocardial infarction, unspecified	0.519	0.481	0.000
I24.1 Dressler's syndrome	0.515	0.484	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.507	0.493	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.498	0.502	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.492	0.507	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.492	0.507	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.492	0.507	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.492	0.507	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.492	0.507	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.492	0.507	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.492	0.507	0.000
C61 Malignant neoplasm of prostate	0.475	0.525	0.000
I23.8 Other current complications following acute myocardial infarction	0.462	0.538	0.000
I20.1 Angina pectoris with documented spasm	0.425	0.574	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.404	0.596	0.000
I25.5 Ischaemic cardiomyopathy	0.404	0.596	0.000
I21.4 Acute subendocardial myocardial infarction	0.310	0.690	0.000
Z95.4 Presence of other heart-valve replacement	0.295	0.705	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.242	0.758	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.224	0.776	0.000
E78.5 Hyperlipidaemia, unspecified	0.186	0.814	0.000
E78.3 Hyperchylomicronaemia	0.172	0.828	0.000
E78.1 Pure hyperglyceridaemia	0.162	0.838	0.000
E78.8 Other disorders of lipoprotein metabolism	0.159	0.841	0.000
E78.4 Other hyperlipidaemia	0.155	0.845	0.000
E78.6 Lipoprotein deficiency	0.145	0.855	0.000
E78.2 Mixed hyperlipidaemia	0.125	0.875	0.000
C60-C63 Malignant neoplasms of male genital organs	0.110	0.890	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.089	0.911	0.000
I24.8 Other forms of acute ischaemic heart disease	0.088	0.912	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.078	0.922	0.000
K22.7 Barrett's oesophagus	0.077	0.923	0.000
I35.0 Aortic (valve) stenosis	0.072	0.928	0.000
S22.30 Fracture of rib (closed)	0.000	0.934	0.066
C62 Malignant neoplasm of testis	0.063	0.937	0.000
S22.3 Fracture of rib	0.000	0.938	0.062
C60 Malignant neoplasm of penis	0.061	0.939	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.941	0.059
C63.9 Male genital organ, unspecified	0.056	0.944	0.000
C63.8 Overlapping lesion of male genital organs	0.056	0.944	0.000
C63.7 Other specified male genital organs	0.056	0.944	0.000
C63.1 Spermatic cord	0.056	0.944	0.000
C63.0 Epididymis	0.056	0.944	0.000
S22.2 Fracture of sternum	0.000	0.944	0.056
C63.2 Scrotum	0.056	0.944	0.000
S22.20 Fracture of sternum (closed)	0.000	0.945	0.055
S22.0 Fracture of thoracic vertebra	0.000	0.946	0.054
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.949	0.051
S22.5 Flail chest	0.000	0.950	0.050
I35.9 Aortic valve disorder, unspecified	0.049	0.951	0.000
I35 Nonrheumatic aortic valve disorders	0.048	0.952	0.000
C62.0 Undescended testis	0.045	0.954	0.000
C60.0 Prepuce	0.045	0.955	0.000
C62.1 Descended testis	0.045	0.955	0.000
S22.31 Fracture of rib (open)	0.000	0.955	0.044
C60.8 Overlapping lesion of penis	0.044	0.956	0.000
C60.2 Body of penis	0.044	0.956	0.000
S22.50 Flail chest (closed)	0.000	0.956	0.043
S22.9 Fracture of bony thorax, part unspecified	0.000	0.958	0.042
S22.8 Fracture of other parts of bony thorax	0.000	0.958	0.042
S22.21 Fracture of sternum (open)	0.000	0.959	0.041
C60.1 Glans penis	0.040	0.960	0.000
S22.4 Multiple fractures of ribs	0.000	0.960	0.040
S22.01 Fracture of thoracic vertebra (open)	0.000	0.961	0.039
I35.2 Aortic (valve) stenosis with insufficiency	0.038	0.962	0.000
S22.51 Flail chest (open)	0.000	0.964	0.036
S22.1 Multiple fractures of thoracic spine	0.000	0.969	0.031
K29.8 Duodenitis	0.031	0.969	0.000
C62.9 Testis, unspecified	0.031	0.969	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.969	0.030
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.969	0.030
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.969	0.030
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.969	0.030
C60.9 Penis, unspecified	0.030	0.969	0.001
S22.41 Multiple fractures of ribs (open)	0.000	0.971	0.028
S22.40 Multiple fractures of ribs (closed)	0.000	0.974	0.026
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.977	0.022
S20-S29 Injuries to the thorax	0.000	0.981	0.019
E11.9 Without complications	0.019	0.981	0.000
O63.0 Prolonged first stage (of labour)	0.018	0.982	0.000
I35.1 Aortic (valve) insufficiency	0.018	0.982	0.000
I35.8 Other aortic valve disorders	0.017	0.983	0.000
S21 Open wound of thorax	0.000	0.984	0.016
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.984	0.016
K29.0 Acute haemorrhagic gastritis	0.015	0.985	0.000
S24 Injury of nerves and spinal cord at thorax level	0.000	0.985	0.015
S27 Injury of other and unspecified intrathoracic organs	0.000	0.985	0.015
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.986	0.014
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.014	0.986	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.000	0.986	0.014
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.000	0.986	0.014
S26 Injury of heart	0.000	0.986	0.014
S25 Injury of blood vessels of thorax	0.000	0.986	0.014
R17 Unspecified jaundice	0.014	0.986	0.000
S29 Other and unspecified injuries of thorax	0.000	0.986	0.014
C82.2 Large cell, follicular	0.000	0.987	0.013
S21.1 Open wound of front wall of thorax	0.000	0.987	0.013
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.987	0.013
O63 Long labour	0.013	0.987	0.000
S21.2 Open wound of back wall of thorax	0.000	0.987	0.013
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.987	0.013
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.987	0.012
K29 Gastritis and duodenitis	0.012	0.988	0.000
C82.3 Follicular lymphoma grade IIIa	0.000	0.988	0.012
S24.1 Other and unspecified injuries of thoracic spinal cord	0.000	0.988	0.012
S27.3 Other injuries of lung	0.000	0.988	0.012
O63.9 Long labour, unspecified	0.012	0.988	0.000
S21.8 Open wound of other parts of thorax	0.000	0.988	0.011
S21.7 Multiple open wounds of thoracic wall	0.000	0.988	0.011
Q21.1 Atrial septal defect	0.000	0.988	0.012
S22.10 Multiple fractures of thoracic spine (closed)	0.001	0.988	0.011
S29.8 Other specified injuries of thorax	0.000	0.988	0.011
S21.0 Open wound of breast	0.000	0.989	0.011
S21.9 Open wound of thorax, part unspecified	0.000	0.989	0.011
K26 Duodenal ulcer	0.011	0.989	0.000
S27.0 Traumatic pneumothorax	0.000	0.989	0.011
C82.4 Follicular lymphoma grade IIIb	0.000	0.989	0.011
Q21 Congenital malformations of cardiac septa	0.000	0.989	0.011
S24.6 Injury of unspecified nerve of thorax	0.000	0.989	0.011
S24.5 Injury of other nerves of thorax	0.000	0.989	0.011
S24.4 Injury of thoracic sympathetic nerves	0.000	0.989	0.011
S24.3 Injury of peripheral nerves of thorax	0.000	0.989	0.011
S24.2 Injury of nerve root of thoracic spine	0.000	0.989	0.011
S24.0 Concussion and oedema of thoracic spinal cord	0.000	0.989	0.011
K29.5 Chronic gastritis, unspecified	0.011	0.989	0.000
S27.9 Injury of unspecified intrathoracic organ	0.000	0.989	0.011
S27.7 Multiple injuries of intrathoracic organs	0.000	0.989	0.011
S27.6 Injury of pleura	0.000	0.989	0.011
S27.5 Injury of thoracic trachea	0.000	0.989	0.011
S27.4 Injury of bronchus	0.000	0.989	0.011
C82.6 Cutaneous follicle centre lymphoma	0.000	0.989	0.010
C82.5 Diffuse follicle centre lymphoma	0.000	0.989	0.010
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.011	0.989	0.000
S27.8 Injury of other specified intrathoracic organs	0.000	0.989	0.010
S23.4 Sprain and strain of ribs and sternum	0.000	0.990	0.010
S23.5 Sprain and strain of other and unspecified parts of thorax	0.000	0.990	0.010
S23.3 Sprain and strain of thoracic spine	0.000	0.990	0.010
S23.2 Dislocation of other and unspecified parts of thorax	0.000	0.990	0.010
S23.1 Dislocation of thoracic vertebra	0.000	0.990	0.010
S23.0 Traumatic rupture of thoracic intervertebral disk	0.000	0.990	0.010
S25.9 Injury of unspecified blood vessel of thorax	0.000	0.990	0.010
S25.8 Injury of other blood vessels of thorax	0.000	0.990	0.010
S25.7 Injury of multiple blood vessels of thorax	0.000	0.990	0.010
S25.5 Injury of intercostal blood vessels	0.000	0.990	0.010
S25.4 Injury of pulmonary blood vessels	0.000	0.990	0.010
S25.3 Injury of innominate or subclavian vein	0.000	0.990	0.010
S25.2 Injury of superior vena cava	0.000	0.990	0.010
S25.1 Injury of innominate or subclavian artery	0.000	0.990	0.010
S25.0 Injury of thoracic aorta	0.000	0.990	0.010
S26.9 Injury of heart, unspecified	0.000	0.990	0.010
S26.8 Other injuries of heart	0.000	0.990	0.010
S26.0 Injury of heart with haemopericardium	0.000	0.990	0.010
S28.1 Traumatic amputation of part of thorax	0.000	0.990	0.010
S28.0 Crushed chest	0.000	0.990	0.010
S27.2 Traumatic heamopneumothorax	0.000	0.990	0.010
Q21.0 Ventricular septal defect	0.000	0.990	0.010
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.990	0.010
S29.7 Multiple injuries of thorax	0.000	0.990	0.010
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.990	0.010
S27.1 Traumatic haemothorax	0.000	0.990	0.010
O63.1 Prolonged second stage (of labour)	0.010	0.990	0.000
K26.3 Acute without haemorrhage or perforation	0.010	0.990	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.009	0.991	0.000
S29.0 Injury of muscle and tendon at thorax level	0.000	0.991	0.009
O02.1 Missed abortion	0.009	0.991	0.000
K29.9 Gastroduodenitis, unspecified	0.009	0.991	0.000
K26.0 Acute with haemorrhage	0.009	0.991	0.000
K26.1 Acute with perforation	0.009	0.991	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.991	0.009
C82.0 Small cleaved cell, follicular	0.000	0.991	0.009
Q21.3 Tetralogy of Fallot	0.000	0.991	0.009
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.991	0.009
K22.0 Achalasia of cardia	0.009	0.991	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.992	0.008
Q21.8 Other congenital malformations of cardiac septa	0.000	0.992	0.008
Q21.4 Aortopulmonary septal defect	0.000	0.992	0.008
Q21.2 Atrioventricular septal defect	0.000	0.992	0.008
S29.9 Unspecified injury of thorax	0.000	0.992	0.008
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.992	0.008
K26.2 Acute with both haemorrhage and perforation	0.008	0.992	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.000	0.992	0.008
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.000	0.992	0.008
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.000	0.992	0.008
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.000	0.992	0.008
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.000	0.992	0.008
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.000	0.992	0.008
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.000	0.992	0.008
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.000	0.992	0.008
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.000	0.992	0.008
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.000	0.992	0.008
K22 Other diseases of oesophagus	0.008	0.992	0.000
K26.4 Chronic or unspecified with haemorrhage	0.008	0.992	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.992	0.008
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.992	0.008
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.000	0.992	0.007
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.000	0.992	0.007
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.000	0.992	0.007
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.000	0.992	0.007
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.000	0.992	0.007
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.000	0.992	0.007
K29.1 Other acute gastritis	0.008	0.992	0.000
O36.8 Maternal care for other specified foetal problems	0.008	0.992	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.992	0.008
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.992	0.007
K29.2 Alcoholic gastritis	0.007	0.992	0.000
S06.3 Focal brain injury	0.000	0.992	0.007
S06.9 Intracranial injury, unspecified	0.000	0.993	0.007
S06 Intracranial injury	0.000	0.993	0.007
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.993	0.007
K26.5 Chronic or unspecified with perforation	0.007	0.993	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.007	0.993	0.000
K20-K31 Diseases of oesophagus, stomach and duodenum	0.007	0.993	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.993	0.007
S06.5 Traumatic subdural haemorrhage	0.000	0.993	0.007
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.993	0.007
M10.0 Idiopathic gout	0.007	0.993	0.000
Q51.3 Bicornate uterus	0.000	0.993	0.007
S06.2 Diffuse brain injury	0.000	0.993	0.007
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.993	0.007
M14.6 Neuropathic arthropathy	0.006	0.994	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.994	0.006
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.994	0.006
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.006	0.994	0.000
M10.04 Idiopathic gout (Hand)	0.006	0.994	0.000
S06.4 Epidural haemorrhage	0.000	0.994	0.006
K22.3 Perforation of oesophagus	0.006	0.994	0.000
M10.06 Idiopathic gout (Lower leg)	0.006	0.994	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.006	0.994	0.000
M90.7 Fracture of bone in neoplastic disease	0.006	0.994	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.994	0.005
O36.6 Maternal care for excessive foetal growth	0.006	0.994	0.000
M10.00 Idiopathic gout (Multiple sites)	0.005	0.994	0.000
M10.09 Idiopathic gout (Site unspecified)	0.005	0.994	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.994	0.005
S06.1 Traumatic cerebral oedema	0.000	0.995	0.005
S06.7 Intracranial injury with prolonged coma	0.000	0.995	0.005
K28 Gastrojejunal ulcer	0.005	0.995	0.000
Q51 Congenital malformations of uterus and cervix	0.000	0.995	0.005
K20 Oesophagitis	0.005	0.995	0.000
S06.8 Other intracranial injuries	0.000	0.995	0.005
M10.02 Idiopathic gout (Upper arm)	0.005	0.995	0.000
K23 Disorders of oesophagus in diseases classified elsewhere	0.005	0.995	0.000
K29.3 Chronic superficial gastritis	0.005	0.995	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.995	0.005
H54.9 Unspecified visual impairment (binocular)	0.005	0.995	0.000
M10.08 Idiopathic gout (Other)	0.005	0.995	0.000
M10.05 Idiopathic gout (Pelvic region and thigh)	0.005	0.995	0.000
M10.03 Idiopathic gout (Forearm)	0.005	0.995	0.000
M10.01 Idiopathic gout (Shoulder region)	0.005	0.995	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.995	0.005
M41.9 Scoliosis, unspecified	0.000	0.995	0.005
O36 Maternal care for other known or suspected foetal problems	0.005	0.995	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.995	0.005
M10 Gout	0.005	0.995	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.005	0.995	0.000
M14 Arthropathies in other diseases classified elsewhere	0.005	0.995	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.005	0.995	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.995	0.005
Q20-Q28 Congenital malformations of the circulatory system	0.000	0.995	0.005
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.995	0.005
F81.9 Developmental disorder of scholastic skills, unspecified	0.005	0.995	0.000
Q51.2 Other doubling of uterus	0.000	0.995	0.005
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.005	0.995	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.995	0.005
K27 Peptic ulcer, site unspecified	0.005	0.995	0.000
K22.5 Diverticulum of oesophagus, acquired	0.004	0.995	0.000
K26.7 Chronic without haemorrhage or perforation	0.004	0.995	0.000
I65.2 Occlusion and stenosis of carotid artery	0.004	0.996	0.000
S06.0 Concussion	0.000	0.996	0.004
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.996	0.004
K29.4 Chronic atrophic gastritis	0.004	0.996	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.000	0.996	0.004
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.004	0.996	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.004	0.996	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.004	0.996	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.004	0.996	0.000
Q51.4 Unicornate uterus	0.000	0.996	0.004
D21.2 Connective and other soft tissue of lower limb, including hip	0.004	0.996	0.000
S20 Superficial injury of thorax	0.000	0.996	0.004
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.996	0.004
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.004	0.996	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.004	0.996	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.996	0.004
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.996	0.004
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.996	0.004
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.996	0.004
K28.7 Chronic without haemorrhage or perforation	0.004	0.996	0.000
K28.6 Chronic or unspecified with both haemorrhage and perforation	0.004	0.996	0.000
K28.5 Chronic or unspecified with perforation	0.004	0.996	0.000
K28.4 Chronic or unspecified with haemorrhage	0.004	0.996	0.000
K28.3 Acute without haemorrhage or perforation	0.004	0.996	0.000
K28.2 Acute with both haemorrhage and perforation	0.004	0.996	0.000
K28.1 Acute with perforation	0.004	0.996	0.000
K28.0 Acute with haemorrhage	0.004	0.996	0.000
O36.9 Maternal care for foetal problem, unspecified	0.004	0.996	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.000	0.996	0.004
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.000	0.996	0.004
Q51.6 Embryonic cyst of cervix	0.000	0.996	0.004
Q51.5 Agenesis and aplasia of cervix	0.000	0.996	0.004
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.000	0.996	0.004
Q51.0 Agenesis and aplasia of uterus	0.000	0.996	0.004
M14.2 Diabetic arthropathy	0.004	0.996	0.000
Q28 Other congenital malformations of circulatory system	0.000	0.996	0.004
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.996	0.004
K23.1 Megaoesophagus in Chagas' disease	0.004	0.996	0.000
K23.0 Tuberculous oesophagitis	0.004	0.996	0.000
O36.4 Maternal care for intra-uterine death	0.004	0.996	0.000
K27.3 Acute without haemorrhage or perforation	0.004	0.996	0.000
Z57.2 Occupational exposure to dust	0.000	0.996	0.004
K23.8 Disorders of oesophagus in other diseases classified elsewhere	0.004	0.996	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.996	0.004
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.004	0.996	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.004	0.996	0.000
K04.8 Radicular cyst	0.004	0.996	0.000
O36.1 Maternal care for other isoimmunisation	0.004	0.996	0.000
Z48.9 Surgical follow-up care, unspecified	0.000	0.996	0.004
Q27 Other congenital malformations of peripheral vascular system	0.000	0.996	0.004
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.996	0.004
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.996	0.004
O36.2 Maternal care for hydrops foetalis	0.004	0.996	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.004	0.996	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.004	0.996	0.000
K29.6 Other gastritis	0.004	0.996	0.000
M10.4 Other secondary gout	0.004	0.996	0.000
M10.3 Gout due to impairment of renal function	0.004	0.996	0.000
M10.2 Drug-induced gout	0.004	0.996	0.000
M10.1 Lead-induced gout	0.004	0.996	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.996	0.004
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.004	0.996	0.000
M14.4 Arthropathy in amyloidosis	0.004	0.996	0.000
M14.3 Lipoid dermatoarthritis	0.004	0.996	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.004	0.996	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.004	0.996	0.000
K22.9 Disease of oesophagus, unspecified	0.004	0.996	0.000
D25.2 Subserosal leiomyoma of uterus	0.004	0.996	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.004	0.996	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.000	0.996	0.004
K25 Gastric ulcer	0.004	0.996	0.000
Q26 Congenital malformations of great veins	0.000	0.996	0.004
Q20 Congenital malformations of cardiac chambers and connexions	0.000	0.996	0.004
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.996	0.003
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.996	0.004
K22.2 Oesophageal obstruction	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.000	0.996	0.004
M05-M14 Inflammatory polyarthropathies	0.004	0.996	0.000
M10.90 Gout, unspecified (Multiple sites)	0.004	0.996	0.000
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.003	0.996	0.000
K27.5 Chronic or unspecified with perforation	0.003	0.996	0.000
K27.4 Chronic or unspecified with haemorrhage	0.003	0.996	0.000
K27.2 Acute with both haemorrhage and perforation	0.003	0.996	0.000
K27.1 Acute with perforation	0.003	0.996	0.000
K27.0 Acute with haemorrhage	0.003	0.996	0.000
M10.9 Gout, unspecified	0.004	0.996	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.996	0.004
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.996	0.003
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.004	0.996	0.000
S06.01 Concussion (with open intracranial wound)	0.000	0.996	0.003
M14.8 Arthropathies in other specified diseases classified elsewhere	0.003	0.997	0.000
K27.7 Chronic without haemorrhage or perforation	0.003	0.997	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.000	0.997	0.003
Q28.3 Other malformations of cerebral vessels	0.000	0.997	0.003
O02 Other abnormal products of conception	0.003	0.997	0.000
K25.3 Acute without haemorrhage or perforation	0.003	0.997	0.000
O36.5 Maternal care for poor foetal growth	0.003	0.997	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.000	0.997	0.003
S20.7 Multiple superficial injuries of thorax	0.000	0.997	0.003
Q50-Q56 Congenital malformations of genital organs	0.000	0.997	0.003
C69.3 Choroid	0.003	0.997	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.997	0.003
K25.0 Acute with haemorrhage	0.003	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.000	0.997	0.003
Q25 Congenital malformations of great arteries	0.000	0.997	0.003
M47.80 Other spondylosis (Multiple sites in spine)	0.003	0.997	0.000
C69.9 Eye, unspecified	0.003	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.000	0.997	0.003
Q28.8 Other specified congenital malformations of circulatory system	0.000	0.997	0.003
Q28.1 Other malformations of precerebral vessels	0.000	0.997	0.003
M11 Other crystal arthropathies	0.003	0.997	0.000
Z40 Prophylactic surgery	0.000	0.997	0.003
K25.1 Acute with perforation	0.003	0.997	0.000
M90 Osteopathies in diseases classified elsewhere	0.003	0.997	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.003	0.997	0.000
K25.5 Chronic or unspecified with perforation	0.003	0.997	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.000	0.997	0.003
N30.8 Other cystitis	0.000	0.997	0.003
M12 Other specific arthropathies	0.003	0.997	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.000	0.997	0.003
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.997	0.003
S20.0 Contusion of breast	0.000	0.997	0.003
S20.3 Other superficial injuries of front wall of thorax	0.000	0.997	0.003
Q63 Other congenital malformations of kidney	0.000	0.997	0.003
O36.0 Maternal care for rhesus isoimmunisation	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.000	0.997	0.003
Q27.2 Other congenital malformations of renal artery	0.000	0.997	0.003
Q27.1 Congenital renal artery stenosis	0.000	0.997	0.003
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.000	0.997	0.003
M41 Scoliosis	0.000	0.997	0.003
M10.19 Lead-induced gout (Site unspecified)	0.003	0.997	0.000
M10.18 Lead-induced gout (Other)	0.003	0.997	0.000
M10.17 Lead-induced gout (Ankle and foot)	0.003	0.997	0.000
M10.16 Lead-induced gout (Lower leg)	0.003	0.997	0.000
M10.15 Lead-induced gout (Pelvic region and thigh)	0.003	0.997	0.000
M10.14 Lead-induced gout (Hand)	0.003	0.997	0.000
M10.13 Lead-induced gout (Forearm)	0.003	0.997	0.000
M10.12 Lead-induced gout (Upper arm)	0.003	0.997	0.000
M10.11 Lead-induced gout (Shoulder region)	0.003	0.997	0.000
M10.10 Lead-induced gout (Multiple sites)	0.003	0.997	0.000
M10.29 Drug-induced gout (Site unspecified)	0.003	0.997	0.000
M10.28 Drug-induced gout (Other)	0.003	0.997	0.000
M10.27 Drug-induced gout (Ankle and foot)	0.003	0.997	0.000
M10.26 Drug-induced gout (Lower leg)	0.003	0.997	0.000
M10.25 Drug-induced gout (Pelvic region and thigh)	0.003	0.997	0.000
M10.24 Drug-induced gout (Hand)	0.003	0.997	0.000
M10.23 Drug-induced gout (Forearm)	0.003	0.997	0.000
M10.22 Drug-induced gout (Upper arm)	0.003	0.997	0.000
M10.21 Drug-induced gout (Shoulder region)	0.003	0.997	0.000
M10.20 Drug-induced gout (Multiple sites)	0.003	0.997	0.000
M10.39 Gout due to impairment of renal function (Site unspecified)	0.003	0.997	0.000
M10.38 Gout due to impairment of renal function (Other)	0.003	0.997	0.000
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.003	0.997	0.000
M10.36 Gout due to impairment of renal function (Lower leg)	0.003	0.997	0.000
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.003	0.997	0.000
M10.34 Gout due to impairment of renal function (Hand)	0.003	0.997	0.000
M10.33 Gout due to impairment of renal function (Forearm)	0.003	0.997	0.000
M10.32 Gout due to impairment of renal function (Upper arm)	0.003	0.997	0.000
M10.31 Gout due to impairment of renal function (Shoulder region)	0.003	0.997	0.000
M10.30 Gout due to impairment of renal function (Multiple sites)	0.003	0.997	0.000
M10.49 Other secondary gout (Site unspecified)	0.003	0.997	0.000
M10.48 Other secondary gout (Other)	0.003	0.997	0.000
M10.47 Other secondary gout (Ankle and foot)	0.003	0.997	0.000
M10.46 Other secondary gout (Lower leg)	0.003	0.997	0.000
M10.45 Other secondary gout (Pelvic region and thigh)	0.003	0.997	0.000
M10.44 Other secondary gout (Hand)	0.003	0.997	0.000
M10.43 Other secondary gout (Forearm)	0.003	0.997	0.000
M10.42 Other secondary gout (Upper arm)	0.003	0.997	0.000
M10.41 Other secondary gout (Shoulder region)	0.003	0.997	0.000
M10.40 Other secondary gout (Multiple sites)	0.003	0.997	0.000
M41.8 Other forms of scoliosis	0.000	0.997	0.003
C69 Malignant neoplasm of eye and adnexa	0.003	0.997	0.000
Q22.1 Congenital pulmonary valve stenosis	0.000	0.997	0.003
O75.0 Maternal distress during labour and delivery	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.000	0.997	0.003
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.003	0.997	0.000
K25.2 Acute with both haemorrhage and perforation	0.003	0.997	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.003	0.997	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.000	0.997	0.003
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.000	0.997	0.003
Q20.6 Isomerism of atrial appendages	0.000	0.997	0.003
Q20.5 Discordant atrioventricular connexion	0.000	0.997	0.003
Q20.4 Double inlet ventricle	0.000	0.997	0.003
Q20.3 Discordant ventriculoarterial connexion	0.000	0.997	0.003
Q20.2 Double outlet left ventricle	0.000	0.997	0.003
Q20.1 Double outlet right ventricle	0.000	0.997	0.003
Q20.0 Common arterial trunk	0.000	0.997	0.003
Q26.9 Congenital malformation of great vein, unspecified	0.000	0.997	0.003
Q26.8 Other congenital malformations of great veins	0.000	0.997	0.003
Q26.6 Portal vein-hepatic artery fistula	0.000	0.997	0.003
Q26.5 Anomalous portal venous connexion	0.000	0.997	0.003
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.000	0.997	0.003
Q26.3 Partial anomalous pulmonary venous connexion	0.000	0.997	0.003
Q26.2 Total anomalous pulmonary venous connexion	0.000	0.997	0.003
Q26.1 Persistent left superior vena cava	0.000	0.997	0.003
Q26.0 Congenital stenosis of vena cava	0.000	0.997	0.003
F81 Specific developmental disorders of scholastic skills	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations