TreeWAS – Variant ID: rs633185

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I20 Angina pectoris	0.999	0.001	0.000
I20.9 Angina pectoris, unspecified	0.996	0.004	0.000
I21 Acute myocardial infarction	0.995	0.005	0.000
I21.4 Acute subendocardial myocardial infarction	0.988	0.012	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.972	0.028	0.000
I20.0 Unstable angina	0.970	0.030	0.000
I25.2 Old myocardial infarction	0.911	0.089	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.843	0.157	0.000
I23 Certain current complications following acute myocardial infarction	0.836	0.164	0.000
I24 Other acute ischaemic heart diseases	0.805	0.195	0.000
I10-I15 Hypertensive diseases	0.784	0.216	0.000
I22 Subsequent myocardial infarction	0.778	0.222	0.000
I25.5 Ischaemic cardiomyopathy	0.752	0.248	0.000
I25.4 Coronary artery aneurysm	0.741	0.259	0.000
Chapter IX Diseases of the circulatory system	0.727	0.273	0.000
I23.8 Other current complications following acute myocardial infarction	0.719	0.281	0.000
I24.1 Dressler's syndrome	0.716	0.284	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.713	0.287	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.712	0.288	0.000
I25.6 Silent myocardial ischaemia	0.700	0.300	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.656	0.344	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.655	0.345	0.000
I24.8 Other forms of acute ischaemic heart disease	0.639	0.361	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.630	0.370	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.624	0.376	0.000
I11 Hypertensive heart disease	0.618	0.382	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.606	0.394	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.600	0.400	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.600	0.400	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.600	0.400	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.600	0.400	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.600	0.400	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.600	0.400	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.600	0.400	0.000
I25.3 Aneurysm of heart	0.589	0.411	0.000
I22.8 Subsequent myocardial infarction of other sites	0.571	0.429	0.000
I05-I09 Chronic rheumatic heart diseases	0.560	0.440	0.000
I13 Hypertensive heart and renal disease	0.556	0.444	0.000
I20.8 Other forms of angina pectoris	0.529	0.471	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.528	0.471	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.516	0.484	0.000
I07 Rheumatic tricuspid valve diseases	0.510	0.490	0.000
I21.9 Acute myocardial infarction, unspecified	0.491	0.509	0.000
I00-I02 Acute rheumatic fever	0.486	0.514	0.000
I07.1 Tricuspid insufficiency	0.474	0.526	0.000
I09 Other rheumatic heart diseases	0.446	0.554	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.426	0.574	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.416	0.583	0.000
I15 Secondary hypertension	0.413	0.587	0.000
I06 Rheumatic aortic valve diseases	0.413	0.587	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.405	0.595	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.398	0.601	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.394	0.605	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.384	0.616	0.000
I74 Arterial embolism and thrombosis	0.381	0.619	0.000
I07.9 Tricuspid valve disease, unspecified	0.365	0.634	0.000
I07.8 Other tricuspid valve diseases	0.365	0.634	0.000
I07.2 Tricuspid stenosis with insufficiency	0.365	0.634	0.000
I07.0 Tricuspid stenosis	0.365	0.634	0.000
I09.9 Rheumatic heart disease, unspecified	0.365	0.635	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.362	0.638	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.360	0.640	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.358	0.642	0.000
I02 Rheumatic chorea	0.348	0.652	0.000
I01 Rheumatic fever with heart involvement	0.348	0.652	0.000
I06.1 Rheumatic aortic insufficiency	0.343	0.656	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.329	0.671	0.000
I09.8 Other specified rheumatic heart diseases	0.320	0.680	0.000
I09.2 Chronic rheumatic pericarditis	0.320	0.680	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.320	0.680	0.000
I09.0 Rheumatic myocarditis	0.320	0.680	0.000
I12 Hypertensive renal disease	0.317	0.683	0.000
I15.0 Renovascular hypertension	0.313	0.687	0.000
I00 Rheumatic fever without mention of heart involvement	0.313	0.687	0.000
I05 Rheumatic mitral valve diseases	0.307	0.693	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.307	0.693	0.000
I20.1 Angina pectoris with documented spasm	0.306	0.694	0.001
I74.9 Embolism and thrombosis of unspecified artery	0.305	0.695	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.299	0.701	0.000
I06.8 Other rheumatic aortic valve diseases	0.296	0.704	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.296	0.704	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.294	0.706	0.000
I78 Diseases of capillaries	0.294	0.706	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.292	0.708	0.000
I70 Atherosclerosis	0.285	0.715	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.285	0.715	0.000
I74.8 Embolism and thrombosis of other arteries	0.281	0.719	0.000
I15.2 Hypertension secondary to endocrine disorders	0.275	0.725	0.000
I15.8 Other secondary hypertension	0.274	0.725	0.000
I73 Other peripheral vascular diseases	0.274	0.726	0.000
I28 Other diseases of pulmonary vessels	0.273	0.727	0.000
I74.5 Embolism and thrombosis of iliac artery	0.270	0.730	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.259	0.741	0.000
I15.9 Seconday hypertension, unspecified	0.254	0.746	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.250	0.750	0.000
I01.8 Other acute rheumatic heart disease	0.250	0.750	0.000
I01.2 Acute rheumatic myocarditis	0.250	0.750	0.000
I01.1 Acute rheumatic endocarditis	0.250	0.750	0.000
I01.0 Acute rheumatic pericarditis	0.250	0.750	0.000
I02.9 Rheumatic chorea without heart involvement	0.250	0.750	0.000
I02.0 Rheumatic chorea with heart involvement	0.250	0.750	0.000
I15.1 Hypertension secondary to other renal disorders	0.249	0.751	0.000
I72 Other aneurysm	0.248	0.752	0.000
I06.0 Rheumatic aortic stenosis	0.230	0.770	0.000
I78.8 Other diseases of capillaries	0.226	0.774	0.000
I05.0 Mitral stenosis	0.226	0.774	0.000
I70.0 Atherosclerosis of aorta	0.224	0.776	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.218	0.782	0.000
I72.3 Aneurysm of iliac artery	0.216	0.784	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.216	0.784	0.000
I78.1 Naevus, nonneoplastic	0.216	0.784	0.000
I05.8 Other mitral valve diseases	0.214	0.786	0.000
I78.9 Disease of capillaries, unspecified	0.213	0.787	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.207	0.793	0.000
I05.9 Mitral valve disease, unspecified	0.206	0.794	0.000
I79.1 Aortitis in diseases classified elsewhere	0.204	0.795	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.204	0.795	0.000
I05.1 Rheumatic mitral insufficiency	0.204	0.796	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.202	0.798	0.000
I08 Multiple valve diseases	0.202	0.798	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.201	0.799	0.000
I70.9 Generalised and unspecified atherosclerosis	0.201	0.799	0.000
I28.8 Other specified diseases of pulmonary vessels	0.201	0.799	0.000
I28.1 Aneurysm of pulmonary artery	0.196	0.804	0.000
I70.8 Atherosclerosis of other arteries	0.193	0.806	0.000
I27 Other pulmonary heart diseases	0.190	0.810	0.000
I73.9 Peripheral vascular disease, unspecified	0.190	0.810	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.189	0.811	0.000
I73.0 Raynaud's syndrome	0.187	0.813	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.187	0.813	0.000
I70.1 Atherosclerosis of renal artery	0.187	0.813	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.186	0.814	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.186	0.814	0.000
I72.2 Aneurysm of renal artery	0.185	0.815	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.185	0.815	0.000
I72.0 Aneurysm of carotid artery	0.180	0.820	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.179	0.821	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.178	0.822	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.178	0.822	0.000
I05.2 Mitral stenosis with insufficiency	0.177	0.822	0.000
I26 Pulmonary embolism	0.174	0.825	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.171	0.829	0.000
I12.9 Hypertensive renal disease without renal failure	0.170	0.830	0.000
I73.8 Other specified peripheral vascular diseases	0.169	0.831	0.000
I72.9 Aneurysm of unspecified site	0.168	0.832	0.000
I72.1 Aneurysm of artery of upper extremity	0.166	0.834	0.000
I27.2 Other secondary pulmonary hypertension	0.163	0.837	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.160	0.839	0.000
I72.8 Aneurysm of other specified arteries	0.159	0.841	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.144	0.855	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.141	0.859	0.000
I77 Other disorders of arteries and arterioles	0.141	0.859	0.000
I08.9 Multiple valve disease, unspecified	0.140	0.860	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.139	0.861	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.138	0.862	0.000
I27.1 Kyphoscoliotic heart disease	0.137	0.863	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.134	0.866	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.134	0.866	0.000
I71 Aortic aneurysm and dissection	0.133	0.867	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.128	0.872	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.128	0.872	0.000
I99 Other and unspecified disorders of circulatory system	0.123	0.877	0.000
I27.9 Pulmonary heart disease, unspecified	0.120	0.880	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.118	0.882	0.000
I08.8 Other multiple valve diseases	0.116	0.884	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.116	0.884	0.000
I97.1 Other functional disturbances following cardiac surgery	0.116	0.884	0.000
I27.8 Other specified pulmonary heart diseases	0.114	0.886	0.000
I77.3 Arterial fibromuscular dysplasia	0.112	0.888	0.000
I12.0 Hypertensive renal disease with renal failure	0.112	0.888	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.111	0.889	0.000
I77.2 Rupture of artery	0.110	0.890	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.106	0.894	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.105	0.895	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.102	0.898	0.000
I77.5 Necrosis of artery	0.101	0.899	0.000
I77.4 Coeliac artery compression syndrome	0.101	0.899	0.000
I97.0 Postcardiotomy syndrome	0.100	0.900	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.097	0.903	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.097	0.903	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.096	0.904	0.000
I77.0 Arteriovenous fistula, acquired	0.096	0.904	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.096	0.904	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.096	0.904	0.000
I77.1 Stricture of artery	0.086	0.914	0.000
I72.4 Aneurysm of artery of lower extremity	0.080	0.919	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.072	0.928	0.000
I27.0 Primary pulmonary hypertension	0.062	0.938	0.000
I71.0 Dissection of aorta [any part]	0.059	0.941	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.054	0.945	0.001
I71.3 Abdominal aortic aneurysm, ruptured	0.054	0.946	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.052	0.948	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.052	0.948	0.000
I98.0 Cardiovascular syphilis	0.052	0.948	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.052	0.948	0.000
I60-I69 Cerebrovascular diseases	0.050	0.950	0.000
I77.8 Other specified disorders of arteries and arterioles	0.042	0.957	0.001
R44.1 Visual hallucinations	0.041	0.959	0.000
I77.6 Arteritis, unspecified	0.040	0.960	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.040	0.960	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.039	0.961	0.001
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.039	0.961	0.000
I63 Cerebral infarction	0.038	0.962	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.037	0.963	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.037	0.963	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.036	0.964	0.000
R44.0 Auditory hallucinations	0.035	0.965	0.000
R44.3 Hallucinations, unspecified	0.035	0.965	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.035	0.965	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.034	0.966	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.033	0.967	0.001
I64 Stroke, not specified as haemorrhage or infarction	0.032	0.968	0.000
I65.1 Occlusion and stenosis of basilar artery	0.030	0.970	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.030	0.970	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.030	0.970	0.000
I69 Sequelae of cerebrovascular disease	0.030	0.970	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.029	0.970	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.029	0.971	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.029	0.971	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.028	0.972	0.000
I95 Hypotension	0.028	0.972	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.028	0.972	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.028	0.972	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.028	0.972	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.028	0.972	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.027	0.972	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.027	0.972	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.027	0.973	0.000
R44.2 Other hallucinations	0.027	0.973	0.000
I68.0 Cerebral amyloid angiopathy	0.026	0.973	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.026	0.974	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.026	0.974	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.026	0.974	0.000
I62 Other nontraumatic intracranial haemorrhage	0.025	0.975	0.000
Z95.1 Presence of aortocoronary bypass graft	0.025	0.975	0.000
I65.2 Occlusion and stenosis of carotid artery	0.024	0.976	0.000
I95.0 Idiopathic hypotension	0.024	0.976	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.023	0.977	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.023	0.977	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.022	0.978	0.000
I08.0 Disorders of both mitral and aortic valves	0.021	0.978	0.001
I63.8 Other cerebral infarction	0.022	0.978	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.022	0.978	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.021	0.978	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.021	0.979	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.021	0.979	0.000
I69.3 Sequelae of cerebral infarction	0.020	0.980	0.000
I95.8 Other hypotension	0.020	0.980	0.000
I63.9 Cerebral infarction, unspecified	0.020	0.980	0.000
I62.1 Nontraumatic extradural haemorrhage	0.019	0.981	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.016	0.984	0.000
Z95.2 Presence of prosthetic heart valve	0.014	0.986	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.014	0.986	0.000
I60 Subarachnoid haemorrhage	0.012	0.986	0.001
Z95.4 Presence of other heart-valve replacement	0.013	0.987	0.000
I61 Intracerebral haemorrhage	0.013	0.987	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.013	0.987	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.012	0.988	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.012	0.988	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.011	0.989	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.010	0.989	0.001
I61.4 Intracerebral haemorrhage in cerebellum	0.010	0.990	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.010	0.990	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.990	0.010
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.009	0.990	0.001
I60.5 Subarachnoid haemorrhage from vertebral artery	0.009	0.990	0.001
I61.8 Other intracerebral haemorrhage	0.010	0.990	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.010	0.990	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.009	0.991	0.001
I67 Other cerebrovascular diseases	0.009	0.991	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.008	0.991	0.001
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.008	0.991	0.001
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.008	0.991	0.001
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.008	0.991	0.001
I60.8 Other subarachnoid haemorrhage	0.008	0.991	0.001
I61.5 Intracerebral haemorrhage, intraventricular	0.008	0.991	0.000
Z11.2 Special screening examination for other bacterial diseases	0.008	0.992	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.007	0.992	0.002
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.008	0.992	0.000
I95.2 Hypotension due to drugs	0.008	0.992	0.000
I67.8 Other specified cerebrovascular diseases	0.008	0.992	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.007	0.993	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.007	0.993	0.000
I67.5 Moyamoya disease	0.007	0.993	0.000
I67.4 Hypertensive encephalopathy	0.007	0.993	0.000
I67.3 Progressive vascular leukoencephalopathy	0.007	0.993	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.006	0.994	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.006	0.994	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.006	0.994	0.000
Z95.3 Presence of xenogenic heart valve	0.006	0.994	0.000
E13.9 Without complications	0.000	0.994	0.006
Z11 Special screening examination for infectious and parasitic diseases	0.006	0.994	0.000
I67.1 Cerebral aneurysm, nonruptured	0.006	0.994	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.005	0.995	0.000
Z11.1 Special screening examination for respiratory tuberculosis	0.005	0.995	0.000
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.005	0.995	0.000
I67.2 Cerebral atherosclerosis	0.005	0.995	0.000
S01.3 Open wound of ear	0.000	0.995	0.005
I95.1 Orthostatic hypotension	0.005	0.995	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.003	0.995	0.001
N20.2 Calculus of kidney with calculus of ureter	0.000	0.995	0.005
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.995	0.005
Z11.8 Special screening examination for other infectious and parasitic diseases	0.004	0.996	0.000
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission	0.004	0.996	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.000	0.996	0.004
C67.5 Bladder neck	0.004	0.996	0.000
Z11.6 Special screening examination for other protozoal diseases and helminthiases	0.004	0.996	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.004	0.996	0.000
M24.26 Disorder of ligament (Lower leg)	0.000	0.996	0.004
I95.9 Hypotension, unspecified	0.004	0.996	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.004	0.996	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.004	0.996	0.000
S42.10 Fracture of scapula (closed)	0.003	0.997	0.000
M24.23 Disorder of ligament (Forearm)	0.000	0.997	0.003
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.003	0.997	0.000
M24.24 Disorder of ligament (Hand)	0.000	0.997	0.003
M24.2 Disorder of ligament	0.000	0.997	0.003
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.003	0.997	0.000
K74.3 Primary biliary cirrhosis	0.000	0.997	0.003
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.997	0.003
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.003	0.997	0.000
Q05.9 Spina bifida, unspecified	0.000	0.997	0.003
Z36.8 Other antenatal screening	0.003	0.997	0.000
Z11.5 Special screening examination for other viral diseases	0.003	0.997	0.000
Z36 Antenatal screening	0.003	0.997	0.000
S01.9 Open wound of head, part unspecified	0.003	0.997	0.000
M33.1 Other dermatomyositis	0.003	0.997	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.997	0.003
C81.9 Hodgkin's disease, unspecified	0.000	0.997	0.003
C81.1 Nodular sclerosis	0.000	0.997	0.003
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.997	0.003
I88 Nonspecific lymphadenitis	0.003	0.997	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.003	0.997	0.000
Z90.2 Acquired absence of lung [part of]	0.003	0.997	0.000
M24.29 Disorder of ligament (Site unspecified)	0.000	0.997	0.003
M24.25 Disorder of ligament (Pelvic region and thigh)	0.000	0.997	0.003
M24.22 Disorder of ligament (Upper arm)	0.000	0.997	0.003
M24.20 Disorder of ligament (Multiple sites)	0.000	0.997	0.003
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.997	0.003
M24.28 Disorder of ligament (Other)	0.000	0.997	0.003
Q05 Spina bifida	0.000	0.997	0.003
D62 Acute posthaemorrhagic anaemia	0.003	0.997	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.997	0.003
R41 Other symptoms and signs involving cognitive functions and awareness	0.003	0.997	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.997	0.003
R41.2 Retrograde amnesia	0.002	0.997	0.000
Z36.5 Antenatal screening for isoimmunisation	0.002	0.997	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.002	0.998	0.000
I82 Other venous embolism and thrombosis	0.002	0.998	0.000
C71.9 Brain, unspecified	0.000	0.998	0.002
Q05.4 Unspecified spina bifida with hydrocephalus	0.000	0.998	0.002
Q05.7 Lumbar spina bifida without hydrocephalus	0.000	0.998	0.002
I88.0 Nonspecific mesenteric lymphadenitis	0.002	0.998	0.000
M47.89 Other spondylosis (Site unspecified)	0.002	0.998	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.002	0.998	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.998	0.002
C81 Hodgkin's disease	0.000	0.998	0.002
I85 Oesophageal varices	0.002	0.998	0.000
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
I81 Portal vein thrombosis	0.002	0.998	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.998	0.002
Q05.8 Sacral spina bifida without hydrocephalus	0.000	0.998	0.002
Q05.6 Thoracic spina bifida without hydrocephalus	0.000	0.998	0.002
Q05.5 Cervical spina bifida without hydrocephalus	0.000	0.998	0.002
Q05.3 Sacral spina bifida with hydrocephalus	0.000	0.998	0.002
Q05.2 Lumbar spina bifida with hydrocephalus	0.000	0.998	0.002
Q05.1 Thoracic spina bifida with hydrocephalus	0.000	0.998	0.002
Q05.0 Cervical spina bifida with hydrocephalus	0.000	0.998	0.002
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.998	0.002
Z95.8 Presence of other cardiac and vascular implants and grafts	0.002	0.998	0.000
S67 Crushing injury of wrist and hand	0.000	0.998	0.002
M33.2 Polymyositis	0.002	0.998	0.000
I82.3 Embolism and thrombosis of renal vein	0.002	0.998	0.000
R43 Disturbances of smell and taste	0.002	0.998	0.000
M25.54 Pain in joint (Hand)	0.002	0.998	0.000
I88.8 Other nonspecific lymphadenitis	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.002	0.998	0.000
R41.0 Disorientation, unspecified	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.002	0.998	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.998	0.002
I82.1 Thrombophlebitis migrans	0.002	0.998	0.000
M24.21 Disorder of ligament (Shoulder region)	0.000	0.998	0.002
C81.0 Lymphocytic predominance	0.000	0.998	0.002
I85.0 Oesophageal varices with bleeding	0.002	0.998	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.000	0.998	0.002
M72.2 Plantar fascial fibromatosis	0.000	0.998	0.002
C81.2 Mixed cellularity	0.000	0.998	0.002
I82.0 Budd-Chiari syndrome	0.002	0.998	0.000
D11.0 Parotid gland	0.000	0.998	0.002
E13 Other specified diabetes mellitus	0.000	0.998	0.002
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.998	0.002
C81.3 Lymphocytic depletion	0.000	0.998	0.002
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.002	0.998	0.000
Q07.0 Arnold-Chiari syndrome	0.000	0.998	0.002
Q21.0 Ventricular septal defect	0.002	0.998	0.000
R43.0 Anosmia	0.002	0.998	0.000
I83 Varicose veins of lower extremities	0.002	0.998	0.000
R41.1 Anterograde amnesia	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.000	0.998	0.002
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.000	0.998	0.002
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.002	0.998	0.000
M33 Dermatopolymyositis	0.002	0.998	0.000
C62.9 Testis, unspecified	0.000	0.998	0.002
T23.0 Burn of unspecified degree of wrist and hand	0.002	0.998	0.000
Z94.8 Other transplanted organ and tissue status	0.002	0.998	0.000
I82.2 Embolism and thrombosis of vena cava	0.002	0.998	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.000	0.998	0.002
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.998	0.002
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
R43.1 Parosmia	0.002	0.998	0.000
C81.7 Other Hodgkin's disease	0.000	0.998	0.002
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.002	0.998	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.998	0.002
D37.7 Other digestive organs	0.002	0.998	0.000
Z95.0 Presence of cardiac pacemaker	0.002	0.998	0.000
L84 Corns and callosities	0.000	0.998	0.002
Q07 Other congenital malformations of nervous system	0.000	0.998	0.002
R46 Symptoms and signs involving appearance and behaviour	0.002	0.998	0.000
C62.1 Descended testis	0.000	0.998	0.002
S42.1 Fracture of scapula	0.002	0.998	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.002	0.998	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.002	0.998	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.000	0.998	0.002
C67.3 Anterior wall of bladder	0.002	0.998	0.000
G45.4 Transient global amnesia	0.002	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
M72.28 Plantar fascial fibromatosis-Other	0.000	0.998	0.001
M72.26 Plantar fascial fibromatosis-Lower Leg	0.000	0.998	0.001
M72.25 Plantar fascial fibromatosis-Pelvic/Thigh	0.000	0.998	0.001
M72.24 Plantar fascial fibromatosis-Hand	0.000	0.998	0.001
M72.23 Plantar fascial fibromatosis-Forearm	0.000	0.998	0.001
M72.22 Plantar fascial fibromatosis-Upper arm	0.000	0.998	0.001
M72.21 Plantar fascial fibromatosis-Shldr region	0.000	0.998	0.001
M72.20 Plantar fascial fibromatosis-Mult sites	0.000	0.998	0.001
M75.9 Shoulder lesion, unspecified	0.000	0.998	0.002
Q18.1 Preauricular sinus and cyst	0.000	0.998	0.002
Q76.1 Klippel-Feil syndrome	0.000	0.998	0.002
R46.0 Very low level of personal hygiene	0.002	0.998	0.000
I87 Other disorders of veins	0.002	0.998	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.000	0.998	0.002
E13.8 With unspecified complications	0.000	0.998	0.001
E13.7 With multiple complications	0.000	0.998	0.001
E13.6 With other specified complications	0.000	0.998	0.001
E13.5 With peripheral circulatory complications	0.000	0.998	0.001
E13.4 With neurological complications	0.000	0.998	0.001
E13.2 With renal complications	0.000	0.998	0.001
E13.1 With ketoacidosis	0.000	0.998	0.001
E13.0 With coma	0.000	0.998	0.001
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
H26.1 Traumatic cataract	0.002	0.998	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.998	0.002
D37.9 Digestive organ, unspecified	0.002	0.998	0.000
Q21.1 Atrial septal defect	0.002	0.998	0.000
Q76.5 Cervical rib	0.000	0.998	0.002
R43.2 Parageusia	0.001	0.998	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.002	0.998	0.000
A49.8 Other bacterial infections of unspecified site	0.000	0.998	0.002
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.998	0.002
M33.0 Juvenile dermatomyositis	0.001	0.998	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.000	0.998	0.002
D37.1 Stomach	0.002	0.998	0.000
E46 Unspecified protein-energy malnutrition	0.002	0.998	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.998	0.002
M33.9 Dermatopolymyositis, unspecified	0.001	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.000	0.998	0.001
Q76.8 Other congenital malformations of bony thorax	0.000	0.998	0.001
Q76.7 Congenital malformation of sternum	0.000	0.998	0.001
Q76.6 Other congenital malformations of ribs	0.000	0.998	0.001
Q76.3 Congenital scoliosis due to congenital bony malformation	0.000	0.998	0.001
Q76.2 Congenital spondylolisthesis	0.000	0.998	0.001
R46.8 Other symptoms and signs involving appearance and behaviour	0.001	0.998	0.000
S05.1 Contusion of eyeball and orbital tissues	0.002	0.998	0.000
Z04.1 Examination and observation following transport accident	0.000	0.998	0.002
M72.29 Plantar fascial fibromatosis-Site unspec	0.000	0.998	0.001
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
J02.8 Acute pharyngitis due to other specified organisms	0.000	0.998	0.001
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.998	0.002
Q07.9 Congenital malformation of nervous system, unspecified	0.000	0.998	0.001
Q21.3 Tetralogy of Fallot	0.001	0.998	0.000
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.001	0.998	0.000
R46.6 Undue concern and preoccupation with stressful events	0.001	0.998	0.000
R46.5 Suspiciousness and marked evasiveness	0.001	0.998	0.000
R46.3 Overactivity	0.001	0.998	0.000
R46.1 Bizarre personal appearance	0.001	0.998	0.000
S42.11 Fracture of scapula (open)	0.001	0.998	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.002	0.998	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.002	0.998	0.000
C07 Malignant neoplasm of parotid gland	0.002	0.998	0.000
C67 Malignant neoplasm of bladder	0.002	0.998	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.001	0.998	0.000
Q01 Encephalocele	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations