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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0182
log Bayes Factor = 91.4459
contains 4 variants:
rs62133575
lBF = 17.858
Chr 2 : 18,239,336
rs17738750
lBF = 24.353
Chr 6 : 51,267,355
rs73210044
lBF = 15.249
Chr 8 : 13,392,360
rs72869965
lBF = 16.524
Chr11 : 16,333,060
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
R07.4 Chest pain, unspecified
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
1.000 0.000 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
R07 Pain in throat and chest
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
N18 Chronic renal failure
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
I73 Other peripheral vascular diseases
1.000 0.000 0.000
R42 Dizziness and giddiness
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
0.999 0.001 0.000
D22 Melanocytic naevi
0.999 0.001 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.999 0.001 0.000
S60-S69 Injuries to the wrist and hand
0.999 0.001 0.000
I73.9 Peripheral vascular disease, unspecified
0.999 0.001 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
R05 Cough
0.998 0.002 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.998 0.002 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
I60-I69 Cerebrovascular diseases
0.998 0.002 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.997 0.003 0.000
I77 Other disorders of arteries and arterioles
0.997 0.003 0.000
N18.9 Chronic renal failure, unspecified
0.997 0.003 0.000
E14 Unspecified diabetes mellitus
0.997 0.003 0.000
R41.0 Disorientation, unspecified
0.996 0.004 0.000
R32 Unspecified urinary incontinence
0.996 0.004 0.000
E65-E68 Obesity and other hyperalimentation
0.996 0.004 0.000
E14.9 Without complications
0.996 0.004 0.000
R30-R39 Symptoms and signs involving the urinary system
0.995 0.005 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.995 0.005 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.995 0.005 0.000
N19 Unspecified renal failure
0.995 0.005 0.000
J95-J99 Other diseases of the respiratory system
0.995 0.005 0.000
Y43 Primarily systemic agents
0.994 0.006 0.000
I10-I15 Hypertensive diseases
0.993 0.007 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.993 0.007 0.000
N18.3 Chronic kidney disease, stage 3
0.993 0.007 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.992 0.008 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.992 0.008 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.991 0.009 0.000
E11.3 With ophthalmic complications
0.991 0.009 0.000
A30-A49 Other bacterial diseases
0.990 0.010 0.000
Z04 Examination and observation for other reasons
0.989 0.011 0.000
I12 Hypertensive renal disease
0.989 0.011 0.000
Y43.3 Other antineoplastic drugs
0.989 0.011 0.000
J98 Other respiratory disorders
0.988 0.012 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.988 0.012 0.000
I05-I09 Chronic rheumatic heart diseases
0.988 0.012 0.000
Z71.8 Other specified counselling
0.988 0.012 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.988 0.012 0.000
E27 Other disorders of adrenal gland
0.987 0.013 0.000
T91 Sequelae of injuries of neck and trunk
0.986 0.014 0.000
Y42.7 Androgens and anabolic congeners
0.986 0.014 0.000
D10-D36 Benign neoplasms
0.986 0.014 0.000
I63 Cerebral infarction
0.985 0.015 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.985 0.015 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.985 0.015 0.000
E66 Obesity
0.984 0.016 0.000
M24 Other specific joint derangements
0.984 0.016 0.000
R50-R69 General symptoms and signs
0.984 0.016 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.983 0.017 0.000
S62 Fracture at wrist and hand level
0.982 0.018 0.000
I69 Sequelae of cerebrovascular disease
0.982 0.018 0.000
M25 Other joint disorders, not elsewhere classified
0.981 0.019 0.000
Y83.8 Other surgical procedures
0.981 0.019 0.000
E66.8 Other obesity
0.980 0.020 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.980 0.020 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.979 0.021 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.979 0.021 0.000
C15 Malignant neoplasm of oesophagus
0.978 0.022 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.978 0.022 0.000
Y86 Sequelae of other accidents
0.978 0.022 0.000
I77.1 Stricture of artery
0.978 0.022 0.000
Y52 Agents primarily affecting the cardiovascular system
0.977 0.023 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.977 0.023 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.976 0.024 0.000
I08 Multiple valve diseases
0.975 0.025 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.974 0.026 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.974 0.026 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.973 0.027 0.000
Z93 Artificial opening status
0.972 0.028 0.000
C18 Malignant neoplasm of colon
0.972 0.028 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.972 0.028 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.971 0.029 0.000
Z02 Examination and encounter for administrative purposes
0.970 0.030 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.970 0.030 0.000
R53 Malaise and fatigue
0.969 0.031 0.000
I12.0 Hypertensive renal disease with renal failure
0.968 0.032 0.000
N99-N99 Other disorders of the genitourinary system
0.967 0.033 0.000
S32 Fracture of lumbar spine and pelvis
0.967 0.033 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.967 0.033 0.000
R07.2 Precordial pain
0.966 0.034 0.000
R04 Haemorrhage from respiratory passages
0.964 0.036 0.000
E29 Testicular dysfunction
0.963 0.037 0.000
F30-F39 Mood [affective] disorders
0.962 0.038 0.000
D22.4 Melanocytic naevi of scalp and neck
0.960 0.040 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.960 0.040 0.000
M70-M79 Other soft tissue disorders
0.960 0.040 0.000
W20-W49 Exposure to inanimate mechanical forces
0.959 0.041 0.000
C18.7 Sigmoid colon
0.958 0.042 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.958 0.042 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.957 0.043 0.000
I95 Hypotension
0.957 0.043 0.000
Z74 Problems related to care-provider dependency
0.957 0.043 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.956 0.044 0.000
R03.1 Nonspecific low blood-pressure reading
0.956 0.044 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.955 0.045 0.000
R04.2 Haemoptysis
0.955 0.045 0.000
I12.9 Hypertensive renal disease without renal failure
0.954 0.046 0.000
Z90.5 Acquired absence of kidney
0.954 0.046 0.000
I08.0 Disorders of both mitral and aortic valves
0.954 0.046 0.000
Z02.8 Other examinations for administrative purposes
0.954 0.046 0.000
S62.5 Fracture of thumb
0.954 0.046 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.954 0.046 0.000
C15.5 Lower third of oesophagus
0.954 0.046 0.000
A49 Bacterial infection of unspecified site
0.953 0.047 0.000
F31 Bipolar affective disorder
0.949 0.051 0.000
I95.2 Hypotension due to drugs
0.946 0.054 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.945 0.055 0.000
W00-W19 Falls
0.944 0.056 0.000
F41 Other anxiety disorders
0.943 0.057 0.000
Z95.4 Presence of other heart-valve replacement
0.943 0.057 0.000
T92 Sequelae of injuries of upper limb
0.943 0.057 0.000
M50-M54 Other dorsopathies
0.942 0.058 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.942 0.058 0.000
D36 Benign neoplasm of other and unspecified sites
0.942 0.058 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.942 0.058 0.000
D26 Other benign neoplasms of uterus
0.940 0.060 0.000
T23 Burn and corrosion of wrist and hand
0.940 0.060 0.000
M54 Dorsalgia
0.939 0.061 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.938 0.062 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.938 0.062 0.000
T90 Sequelae of injuries of head
0.938 0.062 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.938 0.062 0.000
S32.0 Fracture of lumbar vertebra
0.936 0.064 0.000
R30 Pain associated with micturition
0.936 0.064 0.000
E29.1 Testicular hypofunction
0.936 0.064 0.000
J98.1 Pulmonary collapse
0.936 0.064 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.934 0.066 0.000
Z04.1 Examination and observation following transport accident
0.934 0.066 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.933 0.067 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.931 0.069 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.930 0.070 0.000
Z95.1 Presence of aortocoronary bypass graft
0.929 0.071 0.000
S69 Other and unspecified injuries of wrist and hand
0.929 0.071 0.000
F03 Unspecified dementia
0.928 0.072 0.000
F41.2 Mixed anxiety and depressive disorder
0.928 0.072 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.927 0.073 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.927 0.073 0.000
R55 Syncope and collapse
0.927 0.073 0.000
R25 Abnormal involuntary movements
0.925 0.075 0.000
E11.2 With renal complications
0.925 0.075 0.000
B35-B49 Mycoses
0.925 0.075 0.000
Z04.9 Examination and observation for unspecified reason
0.925 0.075 0.000
M54.3 Sciatica
0.925 0.075 0.000
J09-J18 Influenza and pneumonia
0.924 0.076 0.000
E65 Localised adiposity
0.924 0.076 0.000
J98.4 Other disorders of lung
0.923 0.077 0.000
S62.50 Fracture of thumb (closed)
0.923 0.077 0.000
M34 Systemic sclerosis
0.923 0.077 0.000
D22.0 Melanocytic naevi of lip
0.921 0.079 0.000
C18.3 Hepatic flexure
0.921 0.079 0.000
M25.8 Other specified joint disorders
0.921 0.079 0.000
Q00-Q07 Congenital malformations of the nervous system
0.920 0.080 0.000
M79.2 Neuralgia and neuritis, unspecified
0.919 0.081 0.000
Chapter VI Diseases of the nervous system
0.918 0.082 0.000
R41.2 Retrograde amnesia
0.915 0.085 0.000
I25.3 Aneurysm of heart
0.915 0.085 0.000
W50-W64 Exposure to animate mechanical forces
0.915 0.085 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.915 0.085 0.000
F43 Reaction to severe stress, and adjustment disorders
0.914 0.086 0.000
I27 Other pulmonary heart diseases
0.914 0.086 0.000
E27.8 Other specified disorders of adrenal gland
0.914 0.086 0.000
Z94 Transplanted organ and tissue status
0.914 0.086 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.914 0.086 0.000
R30.0 Dysuria
0.913 0.087 0.000
S10-S19 Injuries to the neck
0.913 0.087 0.000
Z83 Family history of other specific disorders
0.912 0.088 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.912 0.088 0.000
Y57 Other and unspecified drugs and medicaments
0.911 0.089 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.911 0.089 0.000
M79.5 Residual foreign body in soft tissue
0.910 0.090 0.000
M54.36 Sciatica (Lumbar region)
0.910 0.090 0.000
R60 Oedema, not elsewhere classified
0.908 0.092 0.000
T91.3 Sequelae of injury of spinal cord
0.908 0.092 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.907 0.093 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.907 0.093 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.906 0.094 0.000
A49.8 Other bacterial infections of unspecified site
0.905 0.095 0.000
C45 Mesothelioma
0.904 0.096 0.000
D11 Benign neoplasm of major salivary glands
0.904 0.096 0.000
N25-N29 Other disorders of kidney and ureter
0.904 0.096 0.000
Z83.5 Family history of eye and ear disorders
0.904 0.096 0.000
Z03.4 Observation for suspected myocardial infarction
0.903 0.097 0.000
M21 Other acquired deformities of limbs
0.902 0.098 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.901 0.099 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.901 0.099 0.000
Z71.2 Person consulting for explanation of investigation findings
0.900 0.100 0.000
W22 Striking against or struck by other objects
0.900 0.100 0.000
E13 Other specified diabetes mellitus
0.899 0.101 0.000
M86-M90 Other osteopathies
0.898 0.102 0.000
I73.0 Raynaud's syndrome
0.897 0.103 0.000
Chapter VII Diseases of the eye and adnexa
0.895 0.105 0.000
M79.1 Myalgia
0.892 0.108 0.000
B15-B19 Viral hepatitis
0.891 0.109 0.000
C71 Malignant neoplasm of brain
0.890 0.110 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.888 0.112 0.000
Z04.3 Examination and observation following other accident
0.887 0.113 0.000
E11.0 With coma
0.886 0.114 0.000
E27.1 Primary adrenocortical insufficiency
0.886 0.114 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.886 0.114 0.000
A40 Streptococcal septicaemia
0.886 0.114 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.885 0.115 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.885 0.115 0.000
M54.1 Radiculopathy
0.884 0.116 0.000
C16 Malignant neoplasm of stomach
0.882 0.118 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.881 0.119 0.000
A00-A09 Intestinal infectious diseases
0.881 0.119 0.000
E34 Other endocrine disorders
0.880 0.120 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.879 0.121 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.879 0.121 0.000
C25 Malignant neoplasm of pancreas
0.878 0.122 0.000
D26.1 Corpus uteri
0.878 0.122 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.877 0.123 0.000
M79.54 Residual foreign body in soft tissue (Hand)
0.876 0.124 0.000
Z93.5 Cystostomy status
0.876 0.124 0.000
Q21 Congenital malformations of cardiac septa
0.876 0.124 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.875 0.125 0.000
S90-S99 Injuries to the ankle and foot
0.875 0.125 0.000
N18.4 Chronic kidney disease, stage 4
0.874 0.126 0.000
R46 Symptoms and signs involving appearance and behaviour
0.874 0.126 0.000
T90.5 Sequelae of intracranial injury
0.873 0.127 0.000
S50-S59 Injuries to the elbow and forearm
0.872 0.128 0.000
M25.3 Other instability of joint
0.871 0.129 0.000
V40-V49 Car occupant injured in transport accident
0.870 0.130 0.000
I25.5 Ischaemic cardiomyopathy
0.870 0.130 0.000
I25.4 Coronary artery aneurysm
0.868 0.132 0.000
Q05 Spina bifida
0.868 0.132 0.000
I74 Arterial embolism and thrombosis
0.868 0.132 0.000
I60 Subarachnoid haemorrhage
0.868 0.132 0.000
Z97 Presence of other devices
0.867 0.133 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.867 0.133 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.867 0.133 0.000
C26.0 Intestinal tract, part unspecified
0.866 0.134 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.866 0.134 0.000
T20 Burn and corrosion of head and neck
0.865 0.135 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.864 0.136 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.864 0.136 0.000
I63.8 Other cerebral infarction
0.863 0.137 0.000
Z75 Problems related to medical facilities and other health care
0.863 0.137 0.000
N99.0 Postprocedural renal failure
0.863 0.137 0.000
Z76 Persons encountering health services in other circumstances
0.862 0.138 0.000
Z04.8 Examination and observation for other specified reasons
0.860 0.140 0.000
S60 Superficial injury of wrist and hand
0.859 0.141 0.000
S20-S29 Injuries to the thorax
0.859 0.141 0.000
S80-S89 Injuries to the knee and lower leg
0.858 0.142 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.858 0.142 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.857 0.143 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.857 0.143 0.000
R50 Fever of unknown origin
0.856 0.144 0.000
Z74.8 Other problems related to care-provider dependency
0.855 0.145 0.000
T90.9 Sequelae of unspecified injury of head
0.853 0.147 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.853 0.147 0.000
C81 Hodgkin's disease
0.853 0.147 0.000
Z74.0 Reduced mobility
0.852 0.148 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.852 0.148 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.852 0.148 0.000
V80-V89 Other land transport accidents
0.852 0.148 0.000
R60.0 Localised oedema
0.852 0.148 0.000
C45.0 Mesothelioma of pleura
0.851 0.149 0.000
W17 Other fall from one level to another
0.851 0.149 0.000
R34 Anuria and oliguria
0.849 0.151 0.000
M54.16 Radiculopathy (Lumbar region)
0.849 0.151 0.000
I77.8 Other specified disorders of arteries and arterioles
0.848 0.152 0.000
H25-H28 Disorders of lens
0.846 0.154 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.845 0.155 0.000
Z94.0 Kidney transplant status
0.844 0.156 0.000
R52 Pain, not elsewhere classified
0.844 0.156 0.000
D26.9 Uterus, unspecified
0.843 0.157 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.842 0.158 0.000
E11.6 With other specified complications
0.842 0.158 0.000
R58 Haemorrhage, not elsewhere classified
0.842 0.158 0.000
L20-L30 Dermatitis and eczema
0.842 0.158 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.841 0.159 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.841 0.159 0.000
A49.1 Streptococcal infection, unspecified
0.841 0.159 0.000
F43.0 Acute stress reaction
0.840 0.160 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.840 0.160 0.000
E16 Other disorders of pancreatic internal secretion
0.840 0.160 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.839 0.161 0.000
S64 Injury of nerves at wrist and hand level
0.839 0.161 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.839 0.161 0.000
I27.2 Other secondary pulmonary hypertension
0.838 0.162 0.000
M79.7 Fibromyalgia
0.838 0.162 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.838 0.162 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.838 0.162 0.000
I27.0 Primary pulmonary hypertension
0.837 0.163 0.000
F30 Manic episode
0.837 0.163 0.000
W13 Fall from, out of or through building or structure
0.837 0.163 0.000
A04 Other bacterial intestinal infections
0.837 0.163 0.000
X60-X84 Intentional self-harm
0.837 0.163 0.000
E11.5 With peripheral circulatory complications
0.837 0.163 0.000
I05 Rheumatic mitral valve diseases
0.836 0.164 0.000
T91.1 Sequelae of fracture of spine
0.834 0.166 0.000
M91-M94 Chondropathies
0.834 0.166 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.834 0.166 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.832 0.168 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.832 0.168 0.000
M24.0 Loose body in joint
0.832 0.168 0.000
Q05.9 Spina bifida, unspecified
0.832 0.168 0.000
J98.9 Respiratory disorder, unspecified
0.831 0.169 0.000
Z90.8 Acquired absence of other organs
0.831 0.169 0.000
C79 Secondary malignant neoplasm of other sites
0.831 0.169 0.000
Z93.0 Tracheostomy status
0.830 0.170 0.000
A80-A89 Viral infections of the central nervous system
0.829 0.171 0.000
M24.1 Other articular cartilage disorders
0.829 0.171 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.829 0.171 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.828 0.172 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.827 0.173 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.827 0.173 0.000
E23 Hypofunction and other disorders of pituitary gland
0.827 0.173 0.000
S69.9 Unspecified injury of wrist and hand
0.827 0.173 0.000
S65 Injury of blood vessels at wrist and hand level
0.827 0.173 0.000
C92 Myeloid leukaemia
0.826 0.174 0.000
E13.9 Without complications
0.826 0.174 0.000
S37 Injury of urinary and pelvic organs
0.826 0.174 0.000
B35 Dermatophytosis
0.825 0.175 0.000
E27.2 Addisonian crisis
0.824 0.176 0.000
M79.9 Soft tissue disorder, unspecified
0.824 0.176 0.000
Chapter VIII Diseases of the ear and mastoid process
0.824 0.176 0.000
M54.4 Lumbago with sciatica
0.824 0.176 0.000
J98.8 Other specified respiratory disorders
0.823 0.177 0.000
Q21.1 Atrial septal defect
0.822 0.178 0.000
Z93.8 Other artificial opening status
0.821 0.179 0.000
T59 Toxic effect of other gases, fumes and vapours
0.821 0.179 0.000
T79-T79 Certain early complications of trauma
0.820 0.180 0.000
W22.9 Unspecified place
0.819 0.181 0.000
H53-H54 Visual disturbances and blindness
0.819 0.181 0.000
C82.4 Follicular lymphoma grade IIIb
0.817 0.183 0.000
A46 Erysipelas
0.817 0.183 0.000
S31 Open wound of abdomen, lower back and pelvis
0.816 0.183 0.000
A04.8 Other specified bacterial intestinal infections
0.816 0.184 0.000
E66.0 Obesity due to excess calories
0.815 0.185 0.000
N25 Disorders resulting from impaired renal tubular function
0.815 0.185 0.000
T51 Toxic effect of alcohol
0.814 0.186 0.000
M24.5 Contracture of joint
0.813 0.186 0.000
M30 Polyarteritis nodosa and related conditions
0.813 0.187 0.000
Q24 Other congenital malformations of heart
0.813 0.187 0.000
W55 Bitten or struck by other mammals
0.812 0.188 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.812 0.188 0.000
M25.0 Haemarthrosis
0.811 0.189 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.811 0.189 0.000
S00-S09 Injuries to the head
0.810 0.190 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.809 0.191 0.000
F42 Obsessive-compulsive disorder
0.809 0.191 0.000
I08.8 Other multiple valve diseases
0.808 0.192 0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis
0.808 0.192 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.808 0.192 0.000
M79.10 Myalgia (Multiple sites)
0.808 0.192 0.000
J60-J70 Lung diseases due to external agents
0.807 0.192 0.000
M79.70 Fibromyalgia (Multiple sites)
0.805 0.195 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.805 0.195 0.000
H60-H62 Diseases of external ear
0.805 0.195 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.805 0.195 0.000
J30-J39 Other diseases of upper respiratory tract
0.805 0.195 0.000
T58 Toxic effect of carbon monoxide
0.803 0.197 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.803 0.197 0.000
M60-M63 Disorders of muscles
0.802 0.198 0.000
F39 Unspecified mood [affective] disorder
0.802 0.198 0.000
L29 Pruritus
0.802 0.198 0.000
R25.2 Cramp and spasm
0.802 0.198 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.802 0.198 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.802 0.198 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.802 0.198 0.000
H54 Blindness and low vision
0.801 0.199 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.801 0.199 0.000
Z71.6 Tobacco abuse counselling
0.801 0.199 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.800 0.199 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.800 0.200 0.000
S69.8 Other specified injuries of wrist and hand
0.800 0.200 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.800 0.200 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.799 0.201 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.799 0.201 0.000
D11.0 Parotid gland
0.799 0.201 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.797 0.203 0.000
M34.8 Other forms of systemic sclerosis
0.796 0.204 0.000
W44 Foreign body entering into or through eye or natural orifice
0.796 0.204 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.796 0.204 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.796 0.204 0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)
0.795 0.205 0.000
F02 Dementia in other diseases classified elsewhere
0.795 0.205 0.000
E26 Hyperaldosteronism
0.795 0.205 0.000
C17 Malignant neoplasm of small intestine
0.794 0.206 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.794 0.206 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.794 0.206 0.000
Y84.1 Kidney dialysis
0.793 0.207 0.000
B49 Unspecified mycosis
0.793 0.207 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.793 0.207 0.000
Y00-Y09 Assault
0.793 0.207 0.000
I67 Other cerebrovascular diseases
0.793 0.207 0.000
J00-J06 Acute upper respiratory infections
0.793 0.207 0.000
Y83.3 Surgical operation with formation of external stoma
0.793 0.207 0.000
H26 Other cataract
0.792 0.208 0.000
H27 Other disorders of lens
0.792 0.208 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.792 0.208 0.000
S62.4 Multiple fractures of metacarpal bones
0.791 0.209 0.000
N27 Small kidney of unknown cause
0.790 0.210 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.790 0.210 0.000
R26 Abnormalities of gait and mobility
0.789 0.211 0.000
I70 Atherosclerosis
0.789 0.211 0.000
R57 Shock, not elsewhere classified
0.789 0.211 0.000
D31 Benign neoplasm of eye and adnexa
0.788 0.211 0.000
D22.9 Melanocytic naevi, unspecified
0.788 0.212 0.000
S83.2 Tear of meniscus, current
0.788 0.212 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.787 0.213 0.000
T23.2 Burn of second degree of wrist and hand
0.787 0.213 0.000
Y42.5 Other oestrogens and progestogens
0.787 0.213 0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)
0.787 0.213 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.787 0.213 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.787 0.213 0.000
Y43.0 Antiallergic and antiemetic drugs
0.787 0.213 0.000
R56 Convulsions, not elsewhere classified
0.786 0.214 0.000
M86 Osteomyelitis
0.785 0.215 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.784 0.216 0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified
0.784 0.216 0.000
I73.8 Other specified peripheral vascular diseases
0.784 0.216 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.784 0.216 0.000
F31.9 Bipolar affective disorder, unspecified
0.783 0.217 0.000
C25.2 Tail of pancreas
0.783 0.217 0.000
Z81 Family history of mental and behavioural disorders
0.782 0.218 0.000
T51.9 Alcohol, unspecified
0.782 0.218 0.000
M22 Disorders of patella
0.782 0.218 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.782 0.218 0.000
M31 Other necrotising vasculopathies
0.782 0.218 0.000
C25.1 Body of pancreas
0.781 0.219 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.781 0.219 0.000
Y57.8 Other drugs and medicaments
0.780 0.220 0.000
C15.3 Upper third of oesophagus
0.780 0.220 0.000
C20 Malignant neoplasm of rectum
0.780 0.220 0.000
H26.4 After-cataract
0.780 0.220 0.000
X50-X57 Overexertion, travel and privation
0.779 0.221 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.779 0.221 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.779 0.221 0.000
M25.7 Osteophyte
0.779 0.221 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.779 0.221 0.000
H61 Other disorders of external ear
0.779 0.221 0.000
R50.9 Fever, unspecified
0.779 0.221 0.000
M25.84 Other specified joint disorders (Hand)
0.779 0.221 0.000
Y89 Sequelae of other external causes
0.779 0.221 0.000
C16.5 Lesser curvature of stomach, unspecified
0.778 0.222 0.000
E11.1 With ketoacidosis
0.777 0.223 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.777 0.223 0.000
M21.4 Flat foot [pes planus] (acquired)
0.777 0.223 0.000
H55-H59 Other disorders of eye and adnexa
0.777 0.223 0.000
M24.2 Disorder of ligament
0.776 0.224 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.776 0.224 0.000
N99.2 Postprocedural adhesions of vagina
0.776 0.224 0.000
S62.51 Fracture of thumb (open)
0.775 0.225 0.000
I72 Other aneurysm
0.775 0.225 0.000
S32.3 Fracture of ilium
0.775 0.225 0.000
I78 Diseases of capillaries
0.774 0.226 0.000
G30-G32 Other degenerative diseases of the nervous system
0.774 0.226 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.774 0.226 0.000
C45.9 Mesothelioma, unspecified
0.773 0.227 0.000
Y84.6 Urinary catheterisation
0.772 0.228 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.771 0.229 0.000
Y83.5 Amputation of limb(s)
0.771 0.229 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.771 0.229 0.000
Z94.4 Liver transplant status
0.770 0.230 0.000
Z90.3 Acquired absence of part of stomach
0.770 0.230 0.000
W22.3 Sports and athletics area
0.770 0.230 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.770 0.230 0.000
T14 Injury of unspecified body region
0.769 0.230 0.000
R52.9 Pain, unspecified
0.769 0.231 0.000
Z94.7 Corneal transplant status
0.768 0.232 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.768 0.232 0.000
W10 Fall on and from stairs and steps
0.767 0.233 0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)
0.767 0.233 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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