TreeWAS – Variant ID: rs445925

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
I20.9 Angina pectoris, unspecified	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.000	1.000
I21 Acute myocardial infarction	0.000	0.000	1.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.000	1.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.000	1.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.001	0.999
Z95.1 Presence of aortocoronary bypass graft	0.000	0.003	0.997
M81.99 Osteoporosis, unspecified (Site unspecified)	0.976	0.024	0.000
M81.9 Osteoporosis, unspecified	0.966	0.034	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.036	0.964
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.042	0.958
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.044	0.956
I24 Other acute ischaemic heart diseases	0.000	0.044	0.956
E78.5 Hyperlipidaemia, unspecified	0.000	0.046	0.954
I25.2 Old myocardial infarction	0.000	0.054	0.946
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.059	0.941
M81 Osteoporosis without pathological fracture	0.938	0.062	0.000
I20.0 Unstable angina	0.000	0.067	0.933
M80-M85 Disorders of bone density and structure	0.923	0.077	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.904	0.096	0.000
M40-M43 Deforming dorsopathies	0.899	0.101	0.000
M70-M79 Other soft tissue disorders	0.887	0.113	0.000
M43 Other deforming dorsopathies	0.880	0.120	0.000
M43.1 Spondylolisthesis	0.862	0.138	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.850	0.150	0.000
M81.98 Osteoporosis, unspecified (Other)	0.844	0.156	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.840	0.160	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.170	0.830
M77 Other enthesopathies	0.827	0.173	0.000
I25.5 Ischaemic cardiomyopathy	0.000	0.184	0.816
M86-M90 Other osteopathies	0.812	0.188	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.804	0.196	0.000
M84 Disorders of continuity of bone	0.804	0.196	0.000
M41 Scoliosis	0.792	0.208	0.000
M40 Kyphosis and lordosis	0.781	0.219	0.000
I25.3 Aneurysm of heart	0.000	0.222	0.778
M43.16 Spondylolisthesis (Lumbar region)	0.769	0.231	0.000
M20-M25 Other joint disorders	0.768	0.232	0.000
M79.0 Rheumatism, unspecified	0.757	0.243	0.000
M77.0 Medial epicondylitis	0.753	0.247	0.000
M89 Other disorders of bone	0.753	0.247	0.000
M79.1 Myalgia	0.750	0.250	0.000
M25 Other joint disorders, not elsewhere classified	0.726	0.274	0.000
I20.8 Other forms of angina pectoris	0.000	0.277	0.723
M41.9 Scoliosis, unspecified	0.722	0.278	0.000
I23 Certain current complications following acute myocardial infarction	0.000	0.278	0.722
M79.5 Residual foreign body in soft tissue	0.720	0.280	0.000
E78.2 Mixed hyperlipidaemia	0.000	0.282	0.718
M72 Fibroblastic disorders	0.717	0.283	0.000
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.283	0.717
M21 Other acquired deformities of limbs	0.716	0.284	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.707	0.293	0.000
M43.2 Other fusion of spine	0.704	0.296	0.000
M81.0 Postmenopausal osteoporosis	0.703	0.297	0.000
M77.4 Metatarsalgia	0.700	0.300	0.000
M77.02 Medial epicondylitis (Upper arm)	0.700	0.300	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.700	0.300	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.698	0.302	0.000
M00-M03 Infectious arthropathies	0.697	0.303	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.693	0.307	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.693	0.307	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.693	0.307	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.693	0.307	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.693	0.307	0.000
M34 Systemic sclerosis	0.692	0.308	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.692	0.308	0.000
M40.2 Other and unspecified kyphosis	0.691	0.309	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.309	0.691
I20.1 Angina pectoris with documented spasm	0.000	0.311	0.689
E78.6 Lipoprotein deficiency	0.000	0.313	0.687
E78.3 Hyperchylomicronaemia	0.000	0.313	0.687
I24.1 Dressler's syndrome	0.000	0.315	0.685
M79.7 Fibromyalgia	0.685	0.315	0.000
M82 Osteoporosis in diseases classified elsewhere	0.685	0.315	0.000
M77.9 Enthesopathy, unspecified	0.680	0.320	0.000
M84.0 Malunion of fracture	0.675	0.325	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.673	0.327	0.000
M81.8 Other osteoporosis	0.672	0.328	0.000
M81.6 Localised osteoporosis [Lequesne]	0.672	0.328	0.000
M81.5 Idiopathic osteoporosis	0.672	0.328	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.672	0.328	0.000
M81.1 Postoophorectomy osteoporosis	0.672	0.328	0.000
M79.19 Myalgia (Site unspecified)	0.668	0.332	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.668	0.332	0.000
M89.0 Algoneurodystrophy	0.668	0.332	0.000
M83 Adult osteomalacia	0.662	0.338	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.339	0.661
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.659	0.341	0.000
M79.8 Other specified soft tissue disorders	0.658	0.342	0.000
M85 Other disorders of bone density and structure	0.658	0.342	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.345	0.655
M71 Other bursopathies	0.650	0.350	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.650	0.350	0.000
M76 Enthesopathies of lower limb, excluding foot	0.647	0.353	0.000
M42 Spinal osteochondrosis	0.645	0.355	0.000
M24 Other specific joint derangements	0.645	0.355	0.000
M89.8 Other specified disorders of bone	0.641	0.359	0.000
M87 Osteonecrosis	0.639	0.361	0.000
E78.4 Other hyperlipidaemia	0.000	0.364	0.636
M73 Soft tissue disorders in diseases classified elsewhere	0.636	0.364	0.000
M43.9 Deforming dorsopathy, unspecified	0.631	0.369	0.000
M43.8 Other specified deforming dorsopathies	0.631	0.369	0.000
M43.6 Torticollis	0.631	0.369	0.000
M43.5 Other recurrent vertebral subluxation	0.631	0.369	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.631	0.369	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.631	0.369	0.000
M89.3 Hypertrophy of bone	0.630	0.370	0.000
M79.18 Myalgia (Other)	0.627	0.372	0.000
M81.2 Osteoporosis of disuse	0.625	0.374	0.000
M91-M94 Chondropathies	0.625	0.375	0.000
M60-M63 Disorders of muscles	0.625	0.375	0.000
M40.29 Other and unspecified kyphosis (Site unspecified)	0.624	0.376	0.000
M86 Osteomyelitis	0.623	0.377	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.623	0.377	0.000
M25.5 Pain in joint	0.620	0.380	0.000
M21.0 Valgus deformity, not elsewhere classified	0.620	0.380	0.000
M84.8 Other disorders of continuity of bone	0.620	0.380	0.000
I25.4 Coronary artery aneurysm	0.000	0.381	0.619
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.618	0.382	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.618	0.382	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.618	0.382	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.618	0.382	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.618	0.382	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.618	0.382	0.000
M79.2 Neuralgia and neuritis, unspecified	0.617	0.383	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.613	0.387	0.000
E78.1 Pure hyperglyceridaemia	0.000	0.387	0.612
M21.3 Wrist or foot drop (acquired)	0.611	0.389	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.610	0.390	0.000
M79.3 Panniculitis, unspecified	0.610	0.390	0.000
M25.50 Pain in joint (Multiple sites)	0.605	0.395	0.000
E78.8 Other disorders of lipoprotein metabolism	0.000	0.396	0.604
M43.0 Spondylolysis	0.604	0.396	0.000
M72.2 Plantar fascial fibromatosis	0.600	0.400	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.595	0.404	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.594	0.406	0.000
M77.8 Other enthesopathies, not elsewhere classified	0.593	0.407	0.000
M77.3 Calcaneal spur	0.593	0.407	0.000
M77.2 Periarthritis of wrist	0.593	0.407	0.000
M79.9 Soft tissue disorder, unspecified	0.593	0.407	0.000
M43.12 Spondylolisthesis (Cervical region)	0.592	0.408	0.000
M81.4 Drug-induced osteoporosis	0.591	0.408	0.000
M79.79 Fibromyalgia (Site unspecified)	0.591	0.409	0.000
M79.08 Rheumatism, unspecified (Other)	0.591	0.409	0.000
I22 Subsequent myocardial infarction	0.000	0.411	0.589
M43.29 Other fusion of spine (Site unspecified)	0.579	0.421	0.000
M25.8 Other specified joint disorders	0.579	0.421	0.000
M21.9 Acquired deformity of limb, unspecified	0.577	0.423	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.577	0.423	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.577	0.423	0.000
M84.9 Disorder of continuity of bone, unspecified	0.576	0.424	0.000
M84.3 Stress fracture, not elsewhere classified	0.576	0.424	0.000
M84.2 Delayed union of fracture	0.576	0.424	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.575	0.425	0.000
M34.9 Systemic sclerosis, unspecified	0.575	0.425	0.000
M80 Osteoporosis with pathological fracture	0.574	0.426	0.000
M40.5 Lordosis, unspecified	0.573	0.427	0.000
M79.56 Residual foreign body in soft tissue (Lower leg)	0.569	0.431	0.000
M41.5 Other secondary scoliosis	0.568	0.432	0.000
M41.4 Neuromuscular scoliosis	0.568	0.432	0.000
M41.3 Thoracogenic scoliosis	0.568	0.432	0.000
M41.2 Other idiopathic scoliosis	0.568	0.432	0.000
M41.1 Juvenile idiopathic scoliosis	0.568	0.432	0.000
M41.0 Infantile idiopathic scoliosis	0.568	0.432	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.565	0.435	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.437	0.563
M24.0 Loose body in joint	0.563	0.437	0.000
M34.8 Other forms of systemic sclerosis	0.562	0.438	0.000
M40.4 Other lordosis	0.560	0.440	0.000
M40.3 Flatback syndrome	0.560	0.440	0.000
M40.1 Other secondary kyphosis	0.560	0.440	0.000
M40.0 Postural kyphosis	0.560	0.440	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.559	0.441	0.000
M84.02 Malunion of fracture (Upper arm)	0.556	0.444	0.000
M34.1 CR(E)ST syndrome	0.555	0.445	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.553	0.447	0.000
M77.94 Enthesopathy, unspecified (Hand)	0.552	0.448	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.550	0.450	0.000
M21.2 Flexion deformity	0.549	0.451	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.549	0.451	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.549	0.451	0.000
M00 Pyogenic arthritis	0.549	0.451	0.000
M70.6 Trochanteric bursitis	0.549	0.451	0.000
M25.3 Other instability of joint	0.548	0.451	0.000
M25.4 Effusion of joint	0.548	0.452	0.000
M84.03 Malunion of fracture (Forearm)	0.548	0.452	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.547	0.453	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.545	0.455	0.000
M32 Systemic lupus erythematosus	0.545	0.455	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.543	0.457	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.543	0.457	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.543	0.457	0.000
M79.04 Rheumatism, unspecified (Hand)	0.543	0.457	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.543	0.457	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.543	0.457	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.543	0.457	0.000
M41.8 Other forms of scoliosis	0.543	0.457	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.543	0.457	0.000
M77.09 Medial epicondylitis (Site unspecified)	0.540	0.460	0.000
M77.08 Medial epicondylitis-Other	0.540	0.460	0.000
M77.07 Medial epicondylitis-Ankle/Foot	0.540	0.460	0.000
M77.06 Medial epicondylitis (Lower leg)	0.540	0.460	0.000
M77.05 Medial epicondylitis (Pelvic region and thigh)	0.540	0.460	0.000
M77.04 Medial epicondylitis-Hand	0.540	0.460	0.000
M77.03 Medial epicondylitis-Forearm	0.540	0.460	0.000
M77.01 Medial epicondylitis-Shldr region	0.540	0.460	0.000
M77.00 Medial epicondylitis (Multiple sites)	0.540	0.460	0.000
M89.6 Osteopathy after poliomyelitis	0.540	0.460	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.540	0.460	0.000
M89.2 Other disorders of bone development and growth	0.540	0.460	0.000
M89.1 Epiphyseal arrest	0.540	0.460	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.540	0.460	0.000
M77.96 Enthesopathy, unspecified (Lower leg)	0.538	0.461	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.462	0.538
M79.17 Myalgia (Ankle and foot)	0.538	0.462	0.000
M79.14 Myalgia (Hand)	0.538	0.462	0.000
M79.13 Myalgia (Forearm)	0.538	0.462	0.000
M79.12 Myalgia (Upper arm)	0.538	0.462	0.000
M79.11 Myalgia (Shoulder region)	0.538	0.462	0.000
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)	0.538	0.462	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.535	0.465	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.535	0.465	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.535	0.465	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.534	0.466	0.000
M30 Polyarteritis nodosa and related conditions	0.532	0.468	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.531	0.469	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.530	0.470	0.000
M77.5 Other enthesopathy of foot	0.528	0.472	0.000
M84.4 Pathological fracture, not elsewhere classified	0.528	0.472	0.000
M25.0 Haemarthrosis	0.528	0.472	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.526	0.474	0.000
M89.04 Algoneurodystrophy (Hand)	0.524	0.476	0.000
M45-M49 Spondylopathies	0.524	0.476	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.523	0.476	0.000
M65-M68 Disorders of synovium and tendon	0.523	0.477	0.000
M21.7 Unequal limb length (acquired)	0.523	0.477	0.000
I23.8 Other current complications following acute myocardial infarction	0.000	0.478	0.522
M25.2 Flail joint	0.521	0.479	0.000
M25.1 Fistula of joint	0.521	0.479	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.519	0.481	0.000
M24.07 Loose body in joint (Ankle and foot)	0.518	0.482	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.518	0.482	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.518	0.482	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.518	0.482	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.518	0.482	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.482	0.517
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.482	0.517
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.482	0.517
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.482	0.517
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.482	0.517
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.482	0.517
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.482	0.517
M89.03 Algoneurodystrophy (Forearm)	0.517	0.483	0.000
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.517	0.483	0.000
M79.58 Residual foreign body in soft tissue (Other)	0.517	0.483	0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.517	0.483	0.000
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.517	0.483	0.000
M79.53 Residual foreign body in soft tissue (Forearm)	0.517	0.483	0.000
M79.52 Residual foreign body in soft tissue (Upper arm)	0.517	0.483	0.000
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.517	0.483	0.000
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.517	0.483	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.516	0.484	0.000
M90 Osteopathies in diseases classified elsewhere	0.515	0.484	0.000
M77.1 Lateral epicondylitis	0.514	0.486	0.000
M72.9 Fibroblastic disorder, unspecified	0.514	0.486	0.000
M72.8 Other fibroblastic disorders	0.514	0.486	0.000
M72.6 Necrotizing fasciitis	0.514	0.486	0.000
M72.5 Fasciitis, not elsewhere classified	0.514	0.486	0.000
M72.4 Pseudosarcomatous fibromatosis	0.514	0.486	0.000
M72.3 Nodular fasciitis	0.514	0.486	0.000
M72.1 Knuckle pads	0.514	0.486	0.000
M82.1 Osteoporosis in endocrine disorders	0.514	0.486	0.000
M21.8 Other specified acquired deformities of limbs	0.514	0.486	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.512	0.488	0.000
M25.59 Pain in joint (Site unspecified)	0.511	0.489	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.510	0.490	0.000
M21.4 Flat foot [pes planus] (acquired)	0.509	0.491	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.507	0.492	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.507	0.493	0.000
M43.28 Other fusion of spine (Sacral and sacrococcygeal region)	0.505	0.495	0.000
M43.27 Other fusion of spine (Lumbosacral region)	0.505	0.495	0.000
M43.26 Other fusion of spine (Lumbar region)	0.505	0.495	0.000
M43.25 Other fusion of spine (Thoracolumbar region)	0.505	0.495	0.000
M43.24 Other fusion of spine (Thoracic region)	0.505	0.495	0.000
M43.23 Other fusion of spine (Cervicothoracic region)	0.505	0.495	0.000
M43.22 Other fusion of spine (Cervical region)	0.505	0.495	0.000
M43.21 Other fusion of spine (Occipito-atlanto-axial region)	0.505	0.495	0.000
M43.20 Other fusion of spine (Multiple sites in spine)	0.505	0.495	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.504	0.496	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.504	0.496	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.504	0.496	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.504	0.496	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.504	0.496	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.504	0.496	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.504	0.496	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.504	0.496	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.504	0.496	0.000
M40.24 Other and unspecified kyphosis (Thoracic region)	0.503	0.497	0.000
M77.49 Metatarsalgia-Site unspec	0.502	0.498	0.000
M77.48 Metatarsalgia-Other	0.502	0.498	0.000
M77.46 Metatarsalgia-Lower Leg	0.502	0.498	0.000
M77.45 Metatarsalgia-Pelvic/Thigh	0.502	0.498	0.000
M77.44 Metatarsalgia-Hand	0.502	0.498	0.000
M77.43 Metatarsalgia-Forearm	0.502	0.498	0.000
M77.42 Metatarsalgia-Upper arm	0.502	0.498	0.000
M77.41 Metatarsalgia-Shldr region	0.502	0.498	0.000
M77.40 Metatarsalgia-Mult sites	0.502	0.498	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.502	0.498	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.502	0.498	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.502	0.498	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.502	0.498	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.502	0.498	0.000
M89.5 Osteolysis	0.501	0.499	0.000
M25.52 Pain in joint (Upper arm)	0.501	0.499	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.500	0.500	0.000
M02 Reactive arthropathies	0.500	0.500	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.500	0.500	0.000
M87.9 Osteonecrosis, unspecified	0.498	0.502	0.000
M85.8 Other specified disorders of bone density and structure	0.497	0.503	0.000
M25.58 Pain in joint (Other)	0.497	0.503	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.496	0.504	0.000
M34.0 Progressive systemic sclerosis	0.496	0.504	0.000
M40.28 Other and unspecified kyphosis (Sacral and sacrococcygeal region)	0.495	0.504	0.000
M40.27 Other and unspecified kyphosis (Lumbosacral region)	0.495	0.504	0.000
M40.26 Other and unspecified kyphosis (Lumbar region)	0.495	0.504	0.000
M40.25 Other and unspecified kyphosis (Thoracolumbar region)	0.495	0.504	0.000
M40.23 Other and unspecified kyphosis (Cervicothoracic region)	0.495	0.504	0.000
M40.22 Other and unspecified kyphosis (Cervical region)	0.495	0.504	0.000
M40.21 Other and unspecified kyphosis (Occipito-atlanto-axial region)	0.495	0.504	0.000
M40.20 Other and unspecified kyphosis (Multiple sites in spine)	0.495	0.504	0.000
M86.9 Osteomyelitis, unspecified	0.495	0.505	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.494	0.505	0.000
M79.10 Myalgia (Multiple sites)	0.493	0.507	0.000
M70.2 Olecranon bursitis	0.493	0.507	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.492	0.508	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.492	0.508	0.000
M79.78 Fibromyalgia (Other)	0.491	0.509	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.491	0.509	0.000
M79.76 Fibromyalgia (Lower leg)	0.491	0.509	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.491	0.509	0.000
M79.74 Fibromyalgia (Hand)	0.491	0.509	0.000
M79.73 Fibromyalgia (Forearm)	0.491	0.509	0.000
M79.72 Fibromyalgia (Upper arm)	0.491	0.509	0.000
M79.71 Fibromyalgia (Shoulder region)	0.491	0.509	0.000
M71.3 Other bursal cyst	0.491	0.509	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.491	0.509	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.491	0.509	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.491	0.509	0.000
M21.6 Other acquired deformities of ankle and foot	0.490	0.509	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.510	0.490
M79.28 Neuralgia and neuritis, unspecified (Other)	0.489	0.511	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.488	0.512	0.000
M33 Dermatopolymyositis	0.488	0.512	0.000
M77.99 Enthesopathy, unspecified (Site unspecified)	0.488	0.512	0.000
M77.98 Enthesopathy, unspecified (Other)	0.488	0.512	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.488	0.512	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.488	0.512	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.488	0.512	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.488	0.512	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.486	0.514	0.000
M88 Paget's disease of bone [osteitis deformans]	0.485	0.515	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.484	0.516	0.000
M84.09 Malunion of fracture (Site unspecified)	0.484	0.516	0.000
M84.08 Malunion of fracture (Other)	0.484	0.516	0.000
M84.06 Malunion of fracture (Lower leg)	0.484	0.516	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.484	0.516	0.000
M84.04 Malunion of fracture (Hand)	0.484	0.516	0.000
M84.01 Malunion of fracture (Shoulder region)	0.484	0.516	0.000
M84.00 Malunion of fracture (Multiple sites)	0.484	0.516	0.000
M76.8 Other enthesopathies of lower limb, excluding foot	0.484	0.516	0.000
M87.2 Osteonecrosis due to previous trauma	0.483	0.517	0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure	0.482	0.517	0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure	0.482	0.517	0.000
M70.7 Other bursitis of hip	0.482	0.517	0.000
M70.3 Other bursitis of elbow	0.482	0.517	0.000
M70.1 Bursitis of hand	0.482	0.517	0.000
M70.0 Chronic crepitant synovitis of hand and wrist	0.482	0.517	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.482	0.518	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.482	0.518	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.482	0.518	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.482	0.518	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.482	0.518	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.482	0.518	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.482	0.518	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.482	0.518	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.482	0.518	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.482	0.518	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.482	0.518	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.482	0.518	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.482	0.518	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.482	0.518	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.482	0.518	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.482	0.518	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.482	0.518	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.482	0.518	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.482	0.518	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.482	0.518	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.482	0.518	0.000
M81.58 Idiopathic osteoporosis (Other)	0.482	0.518	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.482	0.518	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.482	0.518	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.482	0.518	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.482	0.518	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.482	0.518	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.482	0.518	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.482	0.518	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.482	0.518	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.482	0.518	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.482	0.518	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.482	0.518	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.482	0.518	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.482	0.518	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.482	0.518	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.482	0.518	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.482	0.518	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.482	0.518	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.482	0.518	0.000
M81.89 Other osteoporosis (Site unspecified)	0.482	0.518	0.000
M81.88 Other osteoporosis (Other)	0.482	0.518	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.482	0.518	0.000
M81.86 Other osteoporosis (Lower leg)	0.482	0.518	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.482	0.518	0.000
M81.84 Other osteoporosis (Hand)	0.482	0.518	0.000
M81.83 Other osteoporosis (Forearm)	0.482	0.518	0.000
M81.82 Other osteoporosis (Upper arm)	0.482	0.518	0.000
M81.81 Other osteoporosis (Shoulder region)	0.482	0.518	0.000
M81.80 Other osteoporosis (Multiple sites)	0.482	0.518	0.000
M79.49 Hypertrophy of (infrapatellar) fat pad-Site unspec	0.479	0.521	0.000
M79.48 Hypertrophy of (infrapatellar) fat pad (Other)	0.479	0.521	0.000
M79.47 Hypertrophy of (infrapatellar) fat pad (Ankle and foot)	0.479	0.521	0.000
M79.45 Hypertrophy of (infrapatellar) fat pad (Pelvic region and thigh)	0.479	0.521	0.000
M79.44 Hypertrophy of (infrapatellar) fat pad (Hand)	0.479	0.521	0.000
M79.43 Hypertrophy of (infrapatellar) fat pad (Forearm)	0.479	0.521	0.000
M79.42 Hypertrophy of (infrapatellar) fat pad (Upper arm)	0.479	0.521	0.000
M79.41 Hypertrophy of (infrapatellar) fat pad (Shoulder region)	0.479	0.521	0.000
M79.40 Hypertrophy of (infrapatellar) fat pad (Multiple sites)	0.479	0.521	0.000
M93 Other osteochondropathies	0.479	0.521	0.000
M89.08 Algoneurodystrophy (Other)	0.479	0.521	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.479	0.521	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.479	0.521	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.479	0.521	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.479	0.521	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.477	0.523	0.000
M83.9 Adult osteomalacia, unspecified	0.474	0.525	0.000
M83.8 Other adult osteomalacia	0.474	0.525	0.000
M83.5 Other drug-induced osteomalacia in adults	0.474	0.525	0.000
M83.4 Aluminum bone disease	0.474	0.525	0.000
M83.3 Adult osteomalacia due to malnutrition	0.474	0.525	0.000
M83.2 Adult osteomalacia due to malabsorption	0.474	0.525	0.000
M83.1 Senile osteomalacia	0.474	0.525	0.000
M83.0 Puerperal osteomalacia	0.474	0.525	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.474	0.526	0.000
M60 Myositis	0.473	0.527	0.000
M79.16 Myalgia (Lower leg)	0.472	0.528	0.000
M22 Disorders of patella	0.472	0.528	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.472	0.528	0.000
M85.9 Disorder of bone density and structure, unspecified	0.472	0.528	0.000
M85.5 Aneurysmal bone cyst	0.472	0.528	0.000
M85.4 Solitary bone cyst	0.472	0.528	0.000
M85.3 Osteitis condensans	0.472	0.528	0.000
M85.2 Hyperostosis of skull	0.472	0.528	0.000
M85.1 Skeletal fluorosis	0.472	0.528	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.472	0.528	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.472	0.528	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.471	0.529	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.470	0.530	0.000
M25.83 Other specified joint disorders (Forearm)	0.470	0.530	0.000
M24.5 Contracture of joint	0.469	0.531	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.469	0.531	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.469	0.531	0.000
M71.9 Bursopathy, unspecified	0.466	0.534	0.000
M71.8 Other specified bursopathies	0.466	0.534	0.000
M71.5 Other bursitis, not elsewhere classified	0.466	0.534	0.000
M71.4 Calcium deposit in bursa	0.466	0.534	0.000
M71.1 Other infective bursitis	0.466	0.534	0.000
M71.0 Abscess of bursa	0.466	0.534	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.466	0.534	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.466	0.534	0.000
M76.9 Enthesopathy of lower limb, unspecified	0.464	0.536	0.000
M76.7 Peroneal tendinitis	0.464	0.536	0.000
M76.5 Patellar tendinitis	0.464	0.536	0.000
M76.4 Tibial collateral bursitis [Pellegrini-Stieda]	0.464	0.536	0.000
M76.3 Iliotibial band syndrome	0.464	0.536	0.000
M76.2 Iliac crest spur	0.464	0.536	0.000
M76.1 Psoas tendinitis	0.464	0.536	0.000
M76.0 Gluteal tendinitis	0.464	0.536	0.000
M42.9 Spinal osteochondrosis, unspecified	0.462	0.537	0.000
M42.1 Adult osteochondrosis of spine	0.462	0.537	0.000
M42.0 Juvenile osteochondrosis of spine	0.462	0.537	0.000
M24.9 Joint derangement, unspecified	0.462	0.537	0.000
M24.7 Protrusio acetabuli	0.462	0.537	0.000
M24.6 Ankylosis of joint	0.462	0.537	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.460	0.540	0.000
M89.84 Other specified disorders of bone (Hand)	0.460	0.540	0.000
M89.83 Other specified disorders of bone (Forearm)	0.460	0.540	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations