TreeWAS – Variant ID: rs4709408

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000
I20.9 Angina pectoris, unspecified	1.000	0.000
I20.0 Unstable angina	1.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	1.000	0.000
Z95.5 Presence of coronary angioplasty implant and graft	1.000	0.000
Z95.1 Presence of aortocoronary bypass graft	1.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	1.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000
I20 Angina pectoris	1.000	0.000
Z95 Presence of cardiac and vascular implants and grafts	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
I25.9 Chronic ischaemic heart disease, unspecified	1.000	0.000
# Top node	1.000	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	1.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	1.000	0.000
E78.5 Hyperlipidaemia, unspecified	1.000	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.999	0.001
I25.2 Old myocardial infarction	0.999	0.001
I10-I15 Hypertensive diseases	0.999	0.001
E70-E90 Metabolic disorders	0.999	0.001
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.999	0.001
I73 Other peripheral vascular diseases	0.998	0.002
Chapter IV Endocrine, nutritional and metabolic diseases	0.998	0.002
I73.9 Peripheral vascular disease, unspecified	0.997	0.003
Chapter XXI Factors influencing health status and contact with health services	0.997	0.003
I10 Essential (primary) hypertension	0.996	0.004
Z95.4 Presence of other heart-valve replacement	0.992	0.008
I20.8 Other forms of angina pectoris	0.992	0.008
Z95.2 Presence of prosthetic heart valve	0.990	0.010
I77 Other disorders of arteries and arterioles	0.981	0.019
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.980	0.020
I60-I69 Cerebrovascular diseases	0.980	0.020
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.974	0.026
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.972	0.028
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.970	0.030
I21 Acute myocardial infarction	0.970	0.030
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.970	0.030
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.969	0.031
I05-I09 Chronic rheumatic heart diseases	0.957	0.043
I22 Subsequent myocardial infarction	0.952	0.048
T36-T50 Poisoning by drugs, medicaments and biological substances	0.942	0.058
I12 Hypertensive renal disease	0.940	0.060
Q20-Q28 Congenital malformations of the circulatory system	0.938	0.062
D70-D77 Other diseases of blood and blood-forming organs	0.935	0.065
I63 Cerebral infarction	0.935	0.065
I08 Multiple valve diseases	0.933	0.067
I77.1 Stricture of artery	0.928	0.072
Z92 Personal history of medical treatment	0.915	0.085
E88 Other metabolic disorders	0.913	0.087
I08.0 Disorders of both mitral and aortic valves	0.911	0.089
I21.9 Acute myocardial infarction, unspecified	0.906	0.094
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.903	0.097
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.901	0.099
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.897	0.103
I21.1 Acute transmural myocardial infarction of inferior wall	0.897	0.103
Z92.2 Personal history of long-term (current) use of other medicaments	0.894	0.106
D70 Agranulocytosis	0.891	0.109
Z95.8 Presence of other cardiac and vascular implants and grafts	0.883	0.117
Q21 Congenital malformations of cardiac septa	0.883	0.117
I72 Other aneurysm	0.882	0.118
I22.9 Subsequent myocardial infarction of unspecified site	0.881	0.119
I30-I52 Other forms of heart disease	0.867	0.133
I35 Nonrheumatic aortic valve disorders	0.862	0.138
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.851	0.149
I65.2 Occlusion and stenosis of carotid artery	0.848	0.152
D55-D59 Haemolytic anaemias	0.848	0.152
I12.0 Hypertensive renal disease with renal failure	0.845	0.155
Chapter XX External causes of morbidity and mortality	0.845	0.155
I24 Other acute ischaemic heart diseases	0.843	0.157
Z88.6 Personal history of allergy to analgesic agent	0.842	0.158
I64 Stroke, not specified as haemorrhage or infarction	0.841	0.159
I35.0 Aortic (valve) stenosis	0.840	0.160
Z88.2 Personal history of allergy to sulphonamides	0.838	0.162
I77.9 Disorder of arteries and arterioles, unspecified	0.837	0.163
I74 Arterial embolism and thrombosis	0.833	0.167
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.830	0.170
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.827	0.173
I77.8 Other specified disorders of arteries and arterioles	0.823	0.176
I12.9 Hypertensive renal disease without renal failure	0.821	0.179
Q21.1 Atrial septal defect	0.820	0.180
I63.8 Other cerebral infarction	0.818	0.182
S20-S29 Injuries to the thorax	0.817	0.183
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.816	0.184
Z89 Acquired absence of limb	0.814	0.186
E20-E35 Disorders of other endocrine glands	0.812	0.188
E87 Other disorders of fluid, electrolyte and acid-base balance	0.811	0.189
I63.9 Cerebral infarction, unspecified	0.811	0.189
T82.3 Mechanical complication of other vascular grafts	0.811	0.189
Z95.3 Presence of xenogenic heart valve	0.810	0.190
T82.1 Mechanical complication of cardiac electronic device	0.807	0.193
I51 Complications and ill-defined descriptions of heart disease	0.804	0.196
I60 Subarachnoid haemorrhage	0.803	0.197
Q80-Q89 Other congenital malformations	0.802	0.198
I21.0 Acute transmural myocardial infarction of anterior wall	0.798	0.202
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.796	0.204
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.795	0.204
T88 Other complications of surgical and medical care, not elsewhere classified	0.793	0.207
D60-D64 Aplastic and other anaemias	0.791	0.208
Z70-Z76 Persons encountering health services in other circumstances	0.791	0.209
E78.9 Disorder of lipoprotein metabolism, unspecified	0.790	0.210
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.789	0.211
E78.4 Other hyperlipidaemia	0.786	0.214
T66-T78 Other and unspecified effects of external causes	0.782	0.218
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.782	0.218
S70-S79 Injuries to the hip and thigh	0.780	0.220
Chapter XXII Codes for special purposes	0.779	0.220
I77.0 Arteriovenous fistula, acquired	0.777	0.223
T87 Complications peculiar to reattachment and amputation	0.774	0.226
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.774	0.226
S90-S99 Injuries to the ankle and foot	0.768	0.232
Z92.6 Personal history of chemotherapy for neoplastic disease	0.767	0.233
I22.8 Subsequent myocardial infarction of other sites	0.765	0.235
I22.1 Subsequent myocardial infarction of inferior wall	0.765	0.235
I09 Other rheumatic heart diseases	0.764	0.236
D73 Diseases of spleen	0.763	0.237
I61 Intracerebral haemorrhage	0.758	0.242
Q24 Other congenital malformations of heart	0.755	0.245
E73 Lactose intolerance	0.754	0.246
X60-X84 Intentional self-harm	0.753	0.247
I25.4 Coronary artery aneurysm	0.751	0.249
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.751	0.249
I72.4 Aneurysm of artery of lower extremity	0.750	0.250
I15 Secondary hypertension	0.748	0.252
I35.8 Other aortic valve disorders	0.748	0.252
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.745	0.255
T82.0 Mechanical complication of heart valve prosthesis	0.744	0.255
I35.1 Aortic (valve) insufficiency	0.744	0.256
I08.2 Disorders of both aortic and tricuspid valves	0.744	0.256
I51.9 Heart disease, unspecified	0.743	0.257
I11 Hypertensive heart disease	0.742	0.258
I25.0 Atherosclerotic cardiovascular disease, so described	0.741	0.258
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.741	0.259
Q27 Other congenital malformations of peripheral vascular system	0.740	0.260
T15-T19 Effects of foreign body entering through natural orifice	0.737	0.262
I25.3 Aneurysm of heart	0.736	0.264
E87.7 Fluid overload	0.734	0.266
X40-X49 Accidental poisoning by and exposure to noxious substances	0.731	0.269
Z84 Family history of other conditions	0.729	0.271
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.727	0.272
S20 Superficial injury of thorax	0.727	0.273
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.727	0.273
Q21.0 Ventricular septal defect	0.727	0.273
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.722	0.278
Q23 Congenital malformations of aortic and mitral valves	0.722	0.278
Chapter I Certain infectious and parasitic diseases	0.720	0.280
Z88.1 Personal history of allergy to other antibiotic agents	0.718	0.282
E78.6 Lipoprotein deficiency	0.717	0.283
E78.3 Hyperchylomicronaemia	0.717	0.283
E78.1 Pure hyperglyceridaemia	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.716	0.283
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.716	0.283
Z82.2 Family history of deafness and hearing loss	0.716	0.283
Z82.1 Family history of blindness and visual loss	0.716	0.283
I13 Hypertensive heart and renal disease	0.716	0.284
E85 Amyloidosis	0.716	0.284
E84 Cystic fibrosis	0.716	0.284
E79 Disorders of purine and pyrimidine metabolism	0.716	0.284
E77 Disorders of glycoprotein metabolism	0.716	0.284
E76 Disorders of glycosaminoglycan metabolism	0.716	0.284
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.716	0.284
E74 Other disorders of carbohydrate metabolism	0.716	0.284
E72 Other disorders of amino-acid metabolism	0.716	0.284
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.716	0.284
E70 Disorders of aromatic amino-acid metabolism	0.716	0.284
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.716	0.284
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.716	0.284
I73.8 Other specified peripheral vascular diseases	0.715	0.284
I73.1 Thromboangiitis obliterans [Buerger]	0.715	0.284
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.715	0.285
E86 Volume depletion	0.715	0.285
D58 Other hereditary haemolytic anaemias	0.714	0.286
E83 Disorders of mineral metabolism	0.712	0.288
T79-T79 Certain early complications of trauma	0.712	0.288
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.711	0.289
E87.5 Hyperkalaemia	0.710	0.290
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.709	0.291
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.708	0.292
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.706	0.294
E78.8 Other disorders of lipoprotein metabolism	0.704	0.295
I77.5 Necrosis of artery	0.703	0.297
I77.4 Coeliac artery compression syndrome	0.703	0.297
I77.3 Arterial fibromuscular dysplasia	0.703	0.297
I77.2 Rupture of artery	0.703	0.297
D63 Anaemia in chronic diseases classified elsewhere	0.703	0.297
T33-T35 Frostbite	0.703	0.297
T26-T28 Burns and corrosions confined to eye and internal organs	0.703	0.297
T20-T25 Burns and corrosions of external body surface, specified by site	0.703	0.297
T00-T07 Injuries involving multiple body regions	0.703	0.297
I68 Cerebrovascular disorders in diseases classified elsewhere	0.702	0.298
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.702	0.298
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.700	0.300
S10-S19 Injuries to the neck	0.700	0.300
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.699	0.301
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.698	0.302
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.698	0.302
I71 Aortic aneurysm and dissection	0.697	0.303
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.697	0.303
T82.4 Mechanical complication of vascular dialysis catheter	0.697	0.303
I31 Other diseases of pericardium	0.696	0.304
E27 Other disorders of adrenal gland	0.696	0.304
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.696	0.304
Q35-Q37 Cleft lip and cleft palate	0.696	0.304
Q30-Q34 Congenital malformations of the respiratory system	0.696	0.304
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.696	0.304
I21.X Presumed acute myicardial infaction (unconfirmed)	0.696	0.304
I21.3 Acute transmural myocardial infarction of unspecified site	0.696	0.304
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.696	0.304
T46 Poisoning by agents primarily affecting the cardiovascular system	0.695	0.305
I72.0 Aneurysm of carotid artery	0.695	0.305
Z92.1 Personal history of long-term (current) use of anticoagulants	0.694	0.306
Z83 Family history of other specific disorders	0.694	0.306
Z92.0 Personal history of contraception	0.692	0.308
D59 Acquired haemolytic anaemia	0.692	0.308
Q38-Q45 Other congenital malformations of the digestive system	0.692	0.308
T50.9 Other and unspecified drugs, medicaments and biological substances	0.691	0.309
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.689	0.311
I21.2 Acute transmural myocardial infarction of other sites	0.688	0.312
I70 Atherosclerosis	0.687	0.313
I06 Rheumatic aortic valve diseases	0.686	0.314
I22.0 Subsequent myocardial infarction of anterior wall	0.683	0.317
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.682	0.318
Z95.0 Presence of cardiac pacemaker	0.681	0.319
D72 Other disorders of white blood cells	0.678	0.322
T88.4 Failed or difficult intubation	0.677	0.323
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.675	0.325
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.675	0.325
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.675	0.325
T41 Poisoning by anaesthetics and therapeutic gases	0.675	0.325
T36 Poisoning by systemic antibiotics	0.675	0.325
Z72 Problems related to lifestyle	0.675	0.325
Chapter VI Diseases of the nervous system	0.674	0.326
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.674	0.326
S40-S49 Injuries to the shoulder and upper arm	0.674	0.326
Z81 Family history of mental and behavioural disorders	0.673	0.326
Q00-Q07 Congenital malformations of the nervous system	0.673	0.327
Q28 Other congenital malformations of circulatory system	0.673	0.327
Q26 Congenital malformations of great veins	0.673	0.327
Q25 Congenital malformations of great arteries	0.673	0.327
Q22 Congenital malformations of pulmonary and tricuspid valves	0.673	0.327
Q20 Congenital malformations of cardiac chambers and connexions	0.673	0.327
Q82 Other congenital malformations of skin	0.671	0.329
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.671	0.329
D74 Methaemoglobinaemia	0.671	0.329
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.671	0.329
D71 Functional disorders of polymorphonuclear neutrophils	0.671	0.329
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.670	0.330
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.670	0.330
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.670	0.330
Q18 Other congenital malformations of face and neck	0.670	0.330
I62 Other nontraumatic intracranial haemorrhage	0.670	0.330
I35.2 Aortic (valve) stenosis with insufficiency	0.669	0.331
D80-D89 Certain disorders involving the immune mechanism	0.669	0.331
I08.9 Multiple valve disease, unspecified	0.669	0.331
I08.8 Other multiple valve diseases	0.669	0.331
I51.6 Cardiovascular disease, unspecified	0.669	0.331
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.668	0.332
T37.8 Other specified systemic anti-infectives and antiparasitics	0.667	0.333
D73.1 Hypersplenism	0.666	0.333
I72.3 Aneurysm of iliac artery	0.666	0.334
Z93 Artificial opening status	0.662	0.338
X10-X19 Contact with heat and hot substances	0.661	0.339
S20.8 Superficial injuries of other and unspecified parts of thorax	0.661	0.339
Y60-Y69 Misadventures to patients during surgical and medical care	0.660	0.340
E40-E46 Malnutrition	0.657	0.343
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.657	0.343
Z89.5 Acquired absence of leg at or below knee	0.656	0.343
Z92.9 Personal history of medical treatment, unspecified	0.656	0.344
Z92.5 Personal history of rehabilitation measures	0.656	0.344
I33 Acute and subacute endocarditis	0.656	0.344
I24.8 Other forms of acute ischaemic heart disease	0.655	0.345
Z82.3 Family history of stroke	0.655	0.345
E88.9 Metabolic disorder, unspecified	0.655	0.345
E88.8 Other specified metabolic disorders	0.655	0.345
E88.3 Tumour lysis syndrome	0.655	0.345
E88.2 Lipomatosis, not elsewhere classified	0.655	0.345
E88.1 Lipodystrophy, not elsewhere classified	0.655	0.345
I51.4 Myocarditis, unspecified	0.655	0.345
T40.4 Other synthetic narcotics	0.653	0.347
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.653	0.347
E50-E64 Other nutritional deficiencies	0.653	0.347
I50 Heart failure	0.652	0.348
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.651	0.349
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.651	0.349
I77.6 Arteritis, unspecified	0.651	0.349
T93 Sequelae of injuries of lower limb	0.649	0.351
E78.2 Mixed hyperlipidaemia	0.648	0.352
Chapter II Neoplasms	0.648	0.352
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.647	0.352
I65.8 Occlusion and stenosis of other precerebral artery	0.647	0.352
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.647	0.352
I65.1 Occlusion and stenosis of basilar artery	0.647	0.352
I65.0 Occlusion and stenosis of vertebral artery	0.647	0.352
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.646	0.354
D75 Other diseases of blood and blood-forming organs	0.646	0.354
G90-G99 Other disorders of the nervous system	0.643	0.357
I36 Nonrheumatic tricuspid valve disorders	0.642	0.357
Z94 Transplanted organ and tissue status	0.642	0.358
X58-X59 Accidental exposure to other and unspecified factors	0.641	0.359
T88.7 Unspecified adverse effect of drug or medicament	0.641	0.359
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.640	0.360
Y00-Y09 Assault	0.640	0.360
I08.1 Disorders of both mitral and tricuspid valves	0.640	0.360
T68 Hypothermia	0.638	0.362
X20-X29 Contact with venomous animals and plants	0.637	0.363
I72.8 Aneurysm of other specified arteries	0.637	0.363
Q50-Q56 Congenital malformations of genital organs	0.634	0.366
Q21.9 Congenital malformation of cardiac septum, unspecified	0.633	0.367
Q21.8 Other congenital malformations of cardiac septa	0.633	0.367
Q21.4 Aortopulmonary septal defect	0.633	0.367
Q21.3 Tetralogy of Fallot	0.633	0.367
Q21.2 Atrioventricular septal defect	0.633	0.367
I72.9 Aneurysm of unspecified site	0.632	0.367
I72.6 Aneurysm and dissection of vertebral artery	0.632	0.367
I72.5 Aneurysm and dissection of other precerebral arteries	0.632	0.367
I72.2 Aneurysm of renal artery	0.632	0.367
I72.1 Aneurysm of artery of upper extremity	0.632	0.367
C50-C50 Malignant neoplasm of breast	0.632	0.368
E87.3 Alkalosis	0.631	0.369
I74.9 Embolism and thrombosis of unspecified artery	0.631	0.369
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.631	0.369
T87.4 Infection of amputation stump	0.631	0.369
G93 Other disorders of brain	0.631	0.369
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.630	0.370
T80 Complications following infusion, transfusion and therapeutic injection	0.628	0.371
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.628	0.372
Q60-Q64 Congenital malformations of the urinary system	0.628	0.372
X78 Intentional self-harm by sharp object	0.627	0.373
I09.9 Rheumatic heart disease, unspecified	0.625	0.375
V40-V49 Car occupant injured in transport accident	0.624	0.376
E20 Hypoparathyroidism	0.624	0.376
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.623	0.377
Y52 Agents primarily affecting the cardiovascular system	0.622	0.378
I52 Other heart disorders in diseases classified elsewhere	0.621	0.378
I48 Atrial fibrillation and flutter	0.621	0.378
I43 Cardiomyopathy in diseases classified elsewhere	0.621	0.378
I41 Myocarditis in diseases classified elsewhere	0.621	0.378
I40 Acute myocarditis	0.621	0.378
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.621	0.378
I37 Pulmonary valve disorders	0.621	0.378
I32 Pericarditis in diseases classified elsewhere	0.621	0.378
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.621	0.379
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.621	0.379
C50 Malignant neoplasm of breast	0.621	0.379
D63.8 Anaemia in other chronic diseases classified elsewhere	0.619	0.380
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.619	0.381
D58.9 Hereditary haemolytic anaemia, unspecified	0.619	0.381
B35-B49 Mycoses	0.616	0.384
E87.1 Hypo-osmolality and hyponatraemia	0.615	0.385
E29 Testicular dysfunction	0.614	0.386
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.614	0.386
Z92.8 Personal history of other medical treatment	0.614	0.386
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.614	0.386
S79 Other and unspecified injuries of hip and thigh	0.613	0.387
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.611	0.389
I46 Cardiac arrest	0.609	0.391
E22 Hyperfunction of pituitary gland	0.609	0.391
D57 Sickle-cell disorders	0.608	0.392
D56 Thalassaemia	0.608	0.392
D55 Anaemia due to enzyme disorders	0.608	0.392
I24.9 Acute ischaemic heart disease, unspecified	0.608	0.392
Z89.4 Acquired absence of foot and ankle	0.607	0.393
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.607	0.393
Z88.5 Personal history of allergy to narcotic agent	0.606	0.394
X50-X57 Overexertion, travel and privation	0.606	0.394
Y35-Y36 Legal intervention and operations of war	0.606	0.394
Y10-Y34 Event of undetermined intent	0.606	0.394
X85-X99 Assault	0.606	0.394
X30-X39 Exposure to forces of nature	0.606	0.394
X00-X09 Exposure to smoke, fire and flames	0.606	0.394
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.606	0.394
W75-W84 Other accidental threats to breathing	0.606	0.394
W65-W74 Accidental drowning and submersion	0.606	0.394
W50-W64 Exposure to animate mechanical forces	0.606	0.394
V98-V99 Other and unspecified transport accidents	0.606	0.394
V95-V97 Air and space transport accidents	0.606	0.394
V90-V94 Water transport accidents	0.606	0.394
V70-V79 Bus occupant injured in transport accident	0.606	0.394
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.606	0.394
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.606	0.394
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.606	0.394
V01-V09 Pedestrian injured in transport accident	0.606	0.394
I24.1 Dressler's syndrome	0.605	0.395
I74.5 Embolism and thrombosis of iliac artery	0.604	0.395
A30-A49 Other bacterial diseases	0.603	0.397
G93.3 Postviral fatigue syndrome	0.602	0.398
E26 Hyperaldosteronism	0.602	0.398
S22 Fracture of rib(s), sternum and thoracic spine	0.600	0.399
I45 Other conduction disorders	0.601	0.399
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.600	0.400
I05 Rheumatic mitral valve diseases	0.600	0.400
I61.9 Intracerebral haemorrhage, unspecified	0.600	0.400
I78 Diseases of capillaries	0.599	0.401
I20.1 Angina pectoris with documented spasm	0.597	0.403
I74.8 Embolism and thrombosis of other arteries	0.597	0.403
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.597	0.403
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.597	0.403
I74.0 Embolism and thrombosis of abdominal aorta	0.597	0.403
E27.1 Primary adrenocortical insufficiency	0.597	0.403
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.596	0.404
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.596	0.404
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.595	0.404
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.595	0.404
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.595	0.404
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.595	0.404
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.595	0.404
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.595	0.404
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.595	0.404
T44.1 Other parasympathomimetics [cholinergics]	0.595	0.404
T44.0 Anticholinesterase agents	0.595	0.404
Y41 Other systemic anti-infectives and antiparasitics	0.594	0.406
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.594	0.406
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.592	0.408
Z75 Problems related to medical facilities and other health care	0.591	0.409
Z76 Persons encountering health services in other circumstances	0.591	0.409
I07 Rheumatic tricuspid valve diseases	0.591	0.409
S70 Superficial injury of hip and thigh	0.591	0.409
T98 Sequelae of other and unspecified effects of external causes	0.590	0.410
I51.0 Cardiac septal defect, acquired	0.589	0.411
Q24.9 Congenital malformation of the heart, unspecified	0.588	0.412
Q24.8 Other specified congenital malformations of heart	0.587	0.413
D73.5 Infarction of spleen	0.586	0.414
X41.9 Unspecified place	0.586	0.414
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.586	0.414
S26 Injury of heart	0.586	0.414
S25 Injury of blood vessels of thorax	0.586	0.414
S24 Injury of nerves and spinal cord at thorax level	0.586	0.414
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.586	0.414
S21 Open wound of thorax	0.586	0.414
Z57 Occupational exposure to risk-factors	0.586	0.414
E24 Cushing's syndrome	0.586	0.414
Z72.2 Drug use	0.585	0.415
T92 Sequelae of injuries of upper limb	0.585	0.415
Z89.9 Acquired absence of limb, unspecified	0.584	0.416
Z89.8 Acquired absence of upper and lower limbs [any level]	0.584	0.416
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.584	0.416
Z89.3 Acquired absence of both upper limbs [any level]	0.584	0.416
Z89.2 Acquired absence of upper limb above wrist	0.584	0.416
Z89.1 Acquired absence of hand and wrist	0.584	0.416
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.583	0.417
S91 Open wound of ankle and foot	0.582	0.418
E35 Disorders of endocrine glands in diseases classified elsewhere	0.582	0.418
E34 Other endocrine disorders	0.582	0.418
E32 Diseases of thymus	0.582	0.418
E31 Polyglandular dysfunction	0.582	0.418
E30 Disorders of puberty, not elsewhere classified	0.582	0.418
E25 Adrenogenital disorders	0.582	0.418
E87.4 Mixed disorder of acid-base balance	0.582	0.418
Z60 Problems related to social environment	0.582	0.418
T17 Foreign body in respiratory tract	0.581	0.419
I35.9 Aortic valve disorder, unspecified	0.581	0.419
V80-V89 Other land transport accidents	0.580	0.420
S90 Superficial injury of ankle and foot	0.580	0.420
D61 Other aplastic anaemias	0.579	0.420
D76.3 Other histiocytosis syndromes	0.578	0.421
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.578	0.422
G35-G37 Demyelinating diseases of the central nervous system	0.578	0.422
I31.3 Pericardial effusion (noninflammatory)	0.578	0.422
E73.9 Lactose intolerance, unspecified	0.578	0.422
T86 Failure and rejection of transplanted organs and tissues	0.577	0.423
K92 Other diseases of digestive system	0.577	0.423
Z98 Other postsurgical states	0.577	0.423
I51.5 Myocardial degeneration	0.576	0.423
I51.3 Intracardiac thrombosis, not elsewhere classified	0.576	0.423
I51.2 Rupture of papillary muscle, not elsewhere classified	0.576	0.423
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.576	0.423
S29 Other and unspecified injuries of thorax	0.576	0.424
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.576	0.424
Chapter VII Diseases of the eye and adnexa	0.576	0.424
I60.8 Other subarachnoid haemorrhage	0.576	0.424
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.576	0.424
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.576	0.424
I60.5 Subarachnoid haemorrhage from vertebral artery	0.576	0.424
I60.4 Subarachnoid haemorrhage from basilar artery	0.576	0.424
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.576	0.424
I73.0 Raynaud's syndrome	0.576	0.424
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.575	0.425
Q84 Other congenital malformations of integument	0.575	0.425
Q83 Congenital malformations of breast	0.575	0.425
Q81 Epidermolysis bullosa	0.575	0.425
Q80 Congenital ichthyosis	0.575	0.425
K92.0 Haematemesis	0.575	0.425
T39.0 Salicylates	0.574	0.425
D59.9 Acquired haemolytic anaemia, unspecified	0.572	0.427
H30-H36 Disorders of choroid and retina	0.572	0.428
I34 Nonrheumatic mitral valve disorders	0.572	0.428
T50.8 Diagnostic agents	0.571	0.429
T50.7 Analeptics and opioid receptor antagonists	0.571	0.429
T50.6 Antidotes and chelating agents, not elsewhere classified	0.571	0.429
T50.5 Appetite depressants	0.571	0.429
T50.4 Drugs affecting uric acid metabolism	0.571	0.429
T50.3 Electrolytic, caloric and water-balance agents	0.571	0.429
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.571	0.429
T50.1 Loop [high-ceiling] diuretics	0.571	0.429
T50.0 Mineralocorticoids and their antagonists	0.571	0.429

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations