TreeWAS – Variant ID: rs7253117

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I25.2 Old myocardial infarction	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I20 Angina pectoris	0.998	0.002	0.000
I21 Acute myocardial infarction	0.995	0.005	0.000
I20.9 Angina pectoris, unspecified	0.985	0.015	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.969	0.031	0.000
I24 Other acute ischaemic heart diseases	0.959	0.041	0.000
I20.8 Other forms of angina pectoris	0.955	0.045	0.000
I22 Subsequent myocardial infarction	0.944	0.056	0.000
I25.5 Ischaemic cardiomyopathy	0.933	0.067	0.000
I24.8 Other forms of acute ischaemic heart disease	0.909	0.091	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.906	0.094	0.000
I21.9 Acute myocardial infarction, unspecified	0.902	0.098	0.000
I20.0 Unstable angina	0.871	0.129	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.867	0.133	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.829	0.171	0.000
I22.8 Subsequent myocardial infarction of other sites	0.822	0.178	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.801	0.199	0.000
I24.1 Dressler's syndrome	0.790	0.210	0.000
I25.6 Silent myocardial ischaemia	0.786	0.214	0.000
I23 Certain current complications following acute myocardial infarction	0.769	0.231	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.755	0.245	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.713	0.286	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.666	0.334	0.000
I20.1 Angina pectoris with documented spasm	0.658	0.342	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.651	0.349	0.000
I23.8 Other current complications following acute myocardial infarction	0.607	0.393	0.000
I21.4 Acute subendocardial myocardial infarction	0.581	0.419	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.551	0.448	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.551	0.448	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.551	0.448	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.551	0.448	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.551	0.448	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.551	0.448	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.546	0.453	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.515	0.485	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.460	0.539	0.000
I25.3 Aneurysm of heart	0.411	0.588	0.000
I25.4 Coronary artery aneurysm	0.409	0.590	0.001
I25.0 Atherosclerotic cardiovascular disease, so described	0.377	0.622	0.001
E78.0 Pure hypercholesterolaemia	0.182	0.818	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.122	0.878	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.119	0.881	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.105	0.895	0.000
E78.2 Mixed hyperlipidaemia	0.097	0.903	0.000
E78.4 Other hyperlipidaemia	0.093	0.907	0.000
E78.5 Hyperlipidaemia, unspecified	0.090	0.910	0.000
E78.6 Lipoprotein deficiency	0.087	0.913	0.000
C67.2 Lateral wall of bladder	0.087	0.913	0.000
C67 Malignant neoplasm of bladder	0.087	0.913	0.000
E78.3 Hyperchylomicronaemia	0.084	0.916	0.000
C67.9 Bladder, unspecified	0.080	0.920	0.000
C67.6 Ureteric orifice	0.078	0.922	0.000
E78.8 Other disorders of lipoprotein metabolism	0.077	0.923	0.000
C67.8 Overlapping lesion of bladder	0.074	0.926	0.000
E78.1 Pure hyperglyceridaemia	0.069	0.931	0.000
C67.5 Bladder neck	0.068	0.932	0.000
C67.4 Posterior wall of bladder	0.068	0.932	0.000
C67.3 Anterior wall of bladder	0.066	0.934	0.000
C67.1 Dome of bladder	0.065	0.935	0.000
C67.7 Urachus	0.062	0.938	0.000
C67.0 Trigone of bladder	0.061	0.939	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.036	0.964	0.000
C64-C68 Malignant neoplasms of urinary tract	0.019	0.981	0.000
C66 Malignant neoplasm of ureter	0.015	0.985	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.015	0.985	0.000
C65 Malignant neoplasm of renal pelvis	0.014	0.986	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.013	0.987	0.000
O64.2 Obstructed labour due to face presentation	0.012	0.988	0.000
H34.8 Other retinal vascular occlusions	0.012	0.988	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.011	0.989	0.000
O64.3 Obstructed labour due to brow presentation	0.011	0.989	0.000
O64.5 Obstructed labour due to compound presentation	0.011	0.989	0.000
O64.4 Obstructed labour due to shoulder presentation	0.011	0.989	0.000
C68.8 Overlapping lesion of urinary organs	0.009	0.990	0.000
C68.1 Paraurethral glands	0.009	0.990	0.000
C68.0 Urethra	0.009	0.991	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.009	0.991	0.000
C68.9 Urinary organ, unspecified	0.009	0.991	0.000
O64.1 Obstructed labour due to breech presentation	0.009	0.991	0.000
N32.8 Other specified disorders of bladder	0.009	0.991	0.000
H34 Retinal vascular occlusions	0.008	0.992	0.000
D47.1 Chronic myeloproliferative disease	0.007	0.993	0.000
H34.2 Other retinal artery occlusions	0.007	0.993	0.000
E13.9 Without complications	0.007	0.993	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.007	0.993	0.000
H34.0 Transient retinal artery occlusion	0.006	0.994	0.000
H50.1 Divergent concomitant strabismus	0.000	0.994	0.006
H34.9 Retinal vascular occlusion, unspecified	0.005	0.994	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.995	0.005
H34.1 Central retinal artery occlusion	0.005	0.995	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.995	0.005
R52.1 Chronic intractable pain	0.005	0.995	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.995	0.005
M06.9 Rheumatoid arthritis, unspecified	0.000	0.995	0.005
Z75.3 Unavailability and inaccessibility of health-care facilities	0.000	0.995	0.005
J35.0 Chronic tonsillitis	0.000	0.995	0.005
G04 Encephalitis, myelitis and encephalomyelitis	0.004	0.995	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.996	0.004
K81.0 Acute cholecystitis	0.004	0.996	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.996	0.004
T86.8 Failure and rejection of other transplanted organs and tissues	0.004	0.996	0.000
S69.9 Unspecified injury of wrist and hand	0.004	0.996	0.000
H04.1 Other disorders of lachrymal gland	0.004	0.996	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.996	0.004
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.996	0.004
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.996	0.004
G04.0 Acute disseminated encephalitis	0.004	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.004	0.996	0.000
E13 Other specified diabetes mellitus	0.004	0.996	0.000
S32.50 Fracture of pubis (closed)	0.000	0.996	0.004
F52.2 Failure of genital response	0.004	0.996	0.000
E24 Cushing's syndrome	0.004	0.996	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.004	0.996	0.000
C71 Malignant neoplasm of brain	0.004	0.996	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.996	0.004
C71.9 Brain, unspecified	0.004	0.996	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.996	0.004
M06.0 Seronegative rheumatoid arthritis	0.000	0.996	0.004
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.003	0.996	0.000
G04.1 Tropical spastic paraplegia	0.003	0.996	0.000
E24.0 Pituitary-dependent Cushing's disease	0.003	0.997	0.000
O61.0 Failed medical induction of labour	0.000	0.997	0.003
C71.3 Parietal lobe	0.003	0.997	0.000
C71.2 Temporal lobe	0.003	0.997	0.000
D72.1 Eosinophilia	0.003	0.997	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.003	0.997	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.003	0.997	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.997	0.003
D47.4 Osteomyelofibrosis	0.003	0.997	0.000
C77.3 Axillary and upper limb lymph nodes	0.003	0.997	0.000
S82.30 Fracture of lower end of tibia (closed)	0.003	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.003	0.997	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.003	0.997	0.000
Z75 Problems related to medical facilities and other health care	0.000	0.997	0.003
E65 Localised adiposity	0.003	0.997	0.000
M06 Other rheumatoid arthritis	0.000	0.997	0.003
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.997	0.003
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.997	0.003
C71.6 Cerebellum	0.003	0.997	0.000
I46.9 Cardiac arrest, unspecified	0.003	0.997	0.000
R09.0 Asphyxia	0.003	0.997	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.003	0.997	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.003	0.997	0.000
N60.3 Fibrosclerosis of breast	0.003	0.997	0.000
S82.31 Fracture of lower end of tibia (open)	0.003	0.997	0.000
C71.1 Frontal lobe	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
B25.9 Cytomegaloviral disease, unspecified	0.003	0.997	0.000
E13.8 With unspecified complications	0.003	0.997	0.000
E13.7 With multiple complications	0.003	0.997	0.000
E13.6 With other specified complications	0.003	0.997	0.000
E13.5 With peripheral circulatory complications	0.003	0.997	0.000
E13.4 With neurological complications	0.003	0.997	0.000
E13.2 With renal complications	0.003	0.997	0.000
E13.1 With ketoacidosis	0.003	0.997	0.000
E13.0 With coma	0.003	0.997	0.000
Z75.8 Other problems related to medical facilities and other health care	0.000	0.997	0.003
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.003	0.997	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.003	0.997	0.000
E24.1 Nelson's syndrome	0.003	0.997	0.000
E13.3 With ophthalmic complications	0.003	0.997	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.003	0.997	0.000
C71.4 Occipital lobe	0.003	0.997	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.997	0.003
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
C71.5 Cerebral ventricle	0.003	0.997	0.000
Z75.5 Holiday relief care	0.000	0.997	0.003
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.003	0.997	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.997	0.003
S72.40 Fracture of lower end of femur (closed)	0.003	0.997	0.000
C71.8 Overlapping lesion of brain	0.003	0.997	0.000
C71.7 Brain stem	0.003	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.997	0.003
E70-E90 Metabolic disorders	0.003	0.997	0.000
Z75.2 Other waiting period for investigation and treatment	0.000	0.997	0.003
E26 Hyperaldosteronism	0.003	0.997	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.997	0.003
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.997	0.003
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.997	0.003
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.997	0.003
E22.1 Hyperprolactinaemia	0.003	0.997	0.000
Z75.4 Unavailability and inaccessibility of other helping agencies	0.000	0.997	0.003
E46 Unspecified protein-energy malnutrition	0.003	0.997	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.997	0.003
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M06.8 Other specified rheumatoid arthritis	0.000	0.997	0.003
Z75.0 Medical services not available in home	0.000	0.997	0.003
D47.3 Essential (haemorrhagic) thrombocythaemia	0.003	0.997	0.000
E11.2 With renal complications	0.003	0.997	0.000
S82.3 Fracture of lower end of tibia	0.003	0.997	0.000
E26.0 Primary hyperaldosteronism	0.003	0.997	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.997	0.002
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
E29 Testicular dysfunction	0.003	0.997	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.997	0.003
Z75.9 Unspecified problem related to medical facilities and other health care	0.000	0.997	0.002
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.997	0.003
C71.0 Cerebrum, except lobes and ventricles	0.002	0.997	0.000
M06.2 Rheumatoid bursitis	0.000	0.997	0.002
H90.3 Sensorineural hearing loss, bilateral	0.000	0.997	0.003
E31 Polyglandular dysfunction	0.002	0.997	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.997	0.002
M54.22 Cervicalgia (Cervical region)	0.003	0.997	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.997	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
E20 Hypoparathyroidism	0.002	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.998	0.000
E22.8 Other hyperfunction of pituitary gland	0.002	0.998	0.000
M06.1 Adult-onset Still's disease	0.000	0.998	0.002
E70 Disorders of aromatic amino-acid metabolism	0.002	0.998	0.000
E40-E46 Malnutrition	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.998	0.002
E25 Adrenogenital disorders	0.002	0.998	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.998	0.002
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
L50.9 Urticaria, unspecified	0.000	0.998	0.002
E28 Ovarian dysfunction	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.998	0.000
L73.9 Follicular disorder, unspecified	0.000	0.998	0.002
E80 Disorders of porphyrin and bilirubin metabolism	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.998	0.002
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.998	0.002
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.998	0.002
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.998	0.002
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.998	0.002
E26.9 Hyperaldosteronism, unspecified	0.002	0.998	0.000
E77 Disorders of glycoprotein metabolism	0.002	0.998	0.000
E76 Disorders of glycosaminoglycan metabolism	0.002	0.998	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.002	0.998	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.002	0.998	0.000
C09.9 Tonsil, unspecified	0.000	0.998	0.002
E26.8 Other hyperaldosteronism	0.002	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.002	0.998	0.000
E72 Other disorders of amino-acid metabolism	0.002	0.998	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
E74 Other disorders of carbohydrate metabolism	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.998	0.002
E32.9 Disease of thymus, unspecified	0.002	0.998	0.000
M06.3 Rheumatoid nodule	0.000	0.998	0.002
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.998	0.002
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.998	0.002
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.998	0.002
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.998	0.002
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.998	0.002
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.998	0.002
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.998	0.002
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.998	0.002
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.998	0.002
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
H93.9 Disorder of ear, unspecified	0.002	0.998	0.000
E84 Cystic fibrosis	0.002	0.998	0.000
E27 Other disorders of adrenal gland	0.002	0.998	0.000
E79 Disorders of purine and pyrimidine metabolism	0.002	0.998	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
E29.1 Testicular hypofunction	0.002	0.998	0.000
K76.8 Other specified diseases of liver	0.000	0.998	0.002
E65-E68 Obesity and other hyperalimentation	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
E34 Other endocrine disorders	0.002	0.998	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.998	0.002
E29.8 Other testicular dysfunction	0.002	0.998	0.000
E29.0 Testicular hyperfunction	0.002	0.998	0.000
E32.8 Other diseases of thymus	0.002	0.998	0.000
E32.1 Abscess of thymus	0.002	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.998	0.000
E73 Lactose intolerance	0.002	0.998	0.000
E80.1 Porphyria cutanea tarda	0.002	0.998	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.998	0.002
M06.28 Rheumatoid bursitis (Other)	0.000	0.998	0.002
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.998	0.002
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.998	0.002
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.998	0.002
M06.24 Rheumatoid bursitis (Hand)	0.000	0.998	0.002
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.998	0.002
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.998	0.002
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.998	0.002
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.998	0.002
E31.0 Autoimmune polyglandular failure	0.002	0.998	0.000
E70.3 Albinism	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.998	0.002
M06.4 Inflammatory polyarthropathy	0.000	0.998	0.002
E31.9 Polyglandular dysfunction, unspecified	0.002	0.998	0.000
E31.8 Other polyglandular dysfunction	0.002	0.998	0.000
E31.1 Polyglandular hyperfunction	0.002	0.998	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.002	0.998	0.000
E89.4 Postprocedural ovarian failure	0.002	0.998	0.000
K26.3 Acute without haemorrhage or perforation	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.002	0.998	0.000
E30.8 Other disorders of puberty	0.002	0.998	0.000
E30.1 Precocious puberty	0.002	0.998	0.000
E30.0 Delayed puberty	0.002	0.998	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.998	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.000	0.998	0.002
E20.8 Other hypoparathyroidism	0.002	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
E80.2 Other porphyria	0.002	0.998	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.002	0.998	0.000
M06.18 Adult-onset Still's disease (Other)	0.000	0.998	0.002
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.998	0.002
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.998	0.002
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.998	0.002
M06.14 Adult-onset Still's disease (Hand)	0.000	0.998	0.002
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.998	0.002
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.998	0.002
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.998	0.002
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.002	0.998	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.002	0.998	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.002	0.998	0.000
E70.2 Disorders of tyrosine metabolism	0.002	0.998	0.000
E70.1 Other hyperphenylalaninaemias	0.002	0.998	0.000
E70.0 Classical phenylketonuria	0.002	0.998	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.002	0.998	0.000
E45 Retarded development following protein-energy malnutrition	0.002	0.998	0.000
E43 Unspecified severe protein-energy malnutrition	0.002	0.998	0.000
E42 Marasmic kwashiorkor	0.002	0.998	0.000
E41 Nutritional marasmus	0.002	0.998	0.000
E40 Kwashiorkor	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.002	0.998	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.002
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.002	0.998	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.998	0.002
E20.9 Hypoparathyroidism, unspecified	0.002	0.998	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.002	0.998	0.000
I35.8 Other aortic valve disorders	0.002	0.998	0.000
D72 Other disorders of white blood cells	0.002	0.998	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.998	0.002
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
E80.5 Crigler-Najjar syndrome	0.002	0.998	0.000
E80.3 Defects of catalase and peroxydase	0.002	0.998	0.000
E80.0 Hereditary erythropoietic porphyria	0.002	0.998	0.000
S32.5 Fracture of pubis	0.000	0.998	0.002
T86.0 Bone-marrow transplant rejection	0.002	0.998	0.000
C18.2 Ascending colon	0.000	0.998	0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.998	0.000
E71.3 Disorders of fatty-acid metabolism	0.002	0.998	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.002	0.998	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.002	0.998	0.000
E71.0 Maple-syrup-urine disease	0.002	0.998	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.002	0.998	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.002	0.998	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.002	0.998	0.000
E76.2 Other mucopolysaccharidoses	0.002	0.998	0.000
E76.1 Mucopolysaccharidosis, type II	0.002	0.998	0.000
E76.0 Mucopolysaccharidosis, type I	0.002	0.998	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.002	0.998	0.000
E77.8 Other disorders of glycoprotein metabolism	0.002	0.998	0.000
E77.1 Defects in glycoprotein degradation	0.002	0.998	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.002	0.998	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.998	0.002
D72.8 Other specified disorders of white blood cells	0.002	0.998	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.002	0.998	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.002	0.998	0.000
E72.5 Disorders of glycine metabolism	0.002	0.998	0.000
E72.4 Disorders of ornithine metabolism	0.002	0.998	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.002	0.998	0.000
E72.2 Disorders of urea cycle metabolism	0.002	0.998	0.000
E72.0 Disorders of amino-acid transport	0.002	0.998	0.000
M41.9 Scoliosis, unspecified	0.002	0.998	0.000
E27.2 Addisonian crisis	0.002	0.998	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.002	0.998	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.002	0.998	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.002	0.998	0.000
E74.2 Disorders of galactose metabolism	0.002	0.998	0.000
E74.1 Disorders of fructose metabolism	0.002	0.998	0.000
T86 Failure and rejection of transplanted organs and tissues	0.002	0.998	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.998	0.002
M06.38 Rheumatoid nodule (Other)	0.000	0.998	0.002
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.998	0.002
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.998	0.002
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.998	0.002
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.002	0.998	0.000
H52.1 Myopia	0.000	0.998	0.002
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.002	0.998	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.002	0.998	0.000
E79.1 Lesch-Nyhan syndrome	0.002	0.998	0.000
E84.8 Cystic fibrosis with other manifestations	0.002	0.998	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.002	0.998	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.002	0.998	0.000
E89.1 Postprocedural hypoinsulinaemia	0.002	0.998	0.000
G82.2 Paraplegia, unspecified	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
E27.5 Adrenomedullary hyperfunction	0.002	0.998	0.000
E27.0 Other adrenocortical overactivity	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
F52.0 Lack or loss of sexual desire	0.002	0.998	0.000
H50.2 Vertical strabismus	0.000	0.998	0.002
E67 Other hyperalimentation	0.002	0.998	0.000
E68 Sequelae of hyperalimentation	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.998	0.002
E34.5 Androgen resistance syndrome	0.002	0.998	0.000
E34.4 Constitutional tall stature	0.002	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.002	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.002	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.002	0.998	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.7 Excessive sexual drive	0.002	0.998	0.000
F52.6 Nonorganic dyspareunia	0.002	0.998	0.000
F52.5 Nonorganic vaginismus	0.002	0.998	0.000
F52.4 Premature ejaculation	0.002	0.998	0.000
F52.3 Orgasmic dysfunction	0.002	0.998	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.002	0.998	0.000
N30.3 Trigonitis	0.002	0.998	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.998	0.002
E22.0 Acromegaly and pituitary gigantism	0.002	0.998	0.000
E73.8 Other lactose intolerance	0.002	0.998	0.000
E73.1 Secondary lactase deficiency	0.002	0.998	0.000
E73.0 Congenital lactase deficiency	0.002	0.998	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.002	0.998	0.000
I46 Cardiac arrest	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.002
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.998	0.002
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.998	0.002
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.998	0.002
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.998	0.002
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.998	0.002
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.998	0.002
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.998	0.002
B25 Cytomegaloviral disease	0.002	0.998	0.000
E50-E64 Other nutritional deficiencies	0.002	0.998	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.002	0.998	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
C32.0 Glottis	0.002	0.998	0.000
E74.0 Glycogen storage disease	0.002	0.998	0.000
N28.1 Cyst of kidney, acquired	0.000	0.998	0.002
E58 Dietary calcium deficiency	0.002	0.998	0.000
M06.33 Rheumatoid nodule (Forearm)	0.000	0.998	0.002
M41.92 Scoliosis, unspecified (Cervical region)	0.002	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.002	0.998	0.000
E80.6 Other disorders of bilirubin metabolism	0.002	0.998	0.000
E84.9 Cystic fibrosis, unspecified	0.002	0.998	0.000
E87.3 Alkalosis	0.002	0.998	0.000
O32.0 Maternal care for unstable lie	0.000	0.998	0.002
M06.34 Rheumatoid nodule (Hand)	0.000	0.998	0.002
S72.41 Fracture of lower end of femur (open)	0.002	0.998	0.000
E44.1 Mild protein-energy malnutrition	0.001	0.998	0.000
E44.0 Moderate protein-energy malnutrition	0.001	0.998	0.000
E75.6 Lipid storage disorder, unspecified	0.001	0.998	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.001	0.998	0.000
E75.3 Sphingolipidosis, unspecified	0.001	0.998	0.000
E75.1 Other gangliosidosis	0.001	0.998	0.000
E75.0 GM2 gangliosidosis	0.001	0.998	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.002	0.998	0.000
S72.4 Fracture of lower end of femur	0.002	0.998	0.000
E61.1 Iron deficiency	0.002	0.998	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.002	0.998	0.000
E89.5 Postprocedural testicular hypofunction	0.002	0.998	0.000
E61 Deficiency of other nutrient elements	0.002	0.998	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.002	0.998	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.998	0.001
B25.0 Cytomegaloviral pneumonitis	0.002	0.998	0.000
D72.9 Disorder of white blood cells, unspecified	0.002	0.998	0.000
D72.0 Genetic anomalies of leukocytes	0.002	0.998	0.000
Y85.0 Sequelae of motor-vehicle accident	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
S32.51 Fracture of pubis (open)	0.000	0.998	0.002
D84.9 Immunodeficiency, unspecified	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.998	0.002
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.002	0.998	0.000
I46.1 Sudden cardiac death, so described	0.002	0.998	0.000
I46.0 Cardiac arrest with successful resuscitation	0.002	0.998	0.000
L28.0 Lichen simplex chronicus	0.002	0.998	0.000
H46 Optic neuritis	0.002	0.998	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.002	0.998	0.000
E80.4 Gilbert's syndrome	0.002	0.998	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
M54.2 Cervicalgia	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations