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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs142130958
log Bayes Factor = 78.6315
Chromosome 19   position 11,190,652  (GRCh37) Explore rs142130958 on Ensembl!
Variant rs142130958 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.001 0.999
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.002 0.998
E78.5 Hyperlipidaemia, unspecified
0.000 0.006 0.994
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.006 0.994
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.013 0.987
I71 Aortic aneurysm and dissection
0.000 0.015 0.985
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.017 0.983
Chapter IX Diseases of the circulatory system
0.000 0.021 0.979
I20.0 Unstable angina
0.000 0.023 0.977
I73 Other peripheral vascular diseases
0.000 0.027 0.973
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.059 0.941
I22 Subsequent myocardial infarction
0.000 0.061 0.939
I73.9 Peripheral vascular disease, unspecified
0.000 0.065 0.935
I21.9 Acute myocardial infarction, unspecified
0.000 0.080 0.920
I73.0 Raynaud's syndrome
0.000 0.089 0.911
I05-I09 Chronic rheumatic heart diseases
0.000 0.104 0.896
I25.3 Aneurysm of heart
0.000 0.115 0.885
I08 Multiple valve diseases
0.000 0.124 0.876
I20.8 Other forms of angina pectoris
0.000 0.131 0.869
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.134 0.866
I77 Other disorders of arteries and arterioles
0.000 0.135 0.865
I24 Other acute ischaemic heart diseases
0.000 0.153 0.847
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.154 0.846
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.159 0.841
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.160 0.840
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.169 0.831
I20.1 Angina pectoris with documented spasm
0.000 0.171 0.829
I22.8 Subsequent myocardial infarction of other sites
0.000 0.177 0.823
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.182 0.818
I77.1 Stricture of artery
0.000 0.191 0.809
I21.4 Acute subendocardial myocardial infarction
0.000 0.195 0.805
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.236 0.764
E78.8 Other disorders of lipoprotein metabolism
0.000 0.237 0.763
I72 Other aneurysm
0.000 0.249 0.750
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.262 0.738
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.265 0.735
I25.5 Ischaemic cardiomyopathy
0.000 0.275 0.725
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.285 0.715
I08.8 Other multiple valve diseases
0.000 0.286 0.714
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.287 0.713
E78.6 Lipoprotein deficiency
0.000 0.288 0.712
E78.3 Hyperchylomicronaemia
0.000 0.288 0.712
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.294 0.706
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.294 0.706
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.294 0.706
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.294 0.706
I00-I02 Acute rheumatic fever
0.000 0.298 0.702
I74 Arterial embolism and thrombosis
0.000 0.299 0.701
I77.0 Arteriovenous fistula, acquired
0.000 0.301 0.699
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.302 0.698
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.317 0.683
I72.4 Aneurysm of artery of lower extremity
0.000 0.322 0.678
E78.2 Mixed hyperlipidaemia
0.000 0.322 0.677
I30-I52 Other forms of heart disease
0.000 0.326 0.674
I08.0 Disorders of both mitral and aortic valves
0.000 0.326 0.674
E78.1 Pure hyperglyceridaemia
0.000 0.336 0.664
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.339 0.661
I38 Endocarditis, valve unspecified
0.000 0.344 0.656
I73.8 Other specified peripheral vascular diseases
0.000 0.346 0.654
I07 Rheumatic tricuspid valve diseases
0.000 0.350 0.649
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.353 0.647
I06 Rheumatic aortic valve diseases
0.000 0.358 0.642
Z95.2 Presence of prosthetic heart valve
0.000 0.359 0.641
E78.4 Other hyperlipidaemia
0.000 0.362 0.638
I08.9 Multiple valve disease, unspecified
0.000 0.372 0.628
I77.5 Necrosis of artery
0.000 0.380 0.620
I77.4 Coeliac artery compression syndrome
0.000 0.380 0.620
I77.3 Arterial fibromuscular dysplasia
0.000 0.380 0.620
I77.2 Rupture of artery
0.000 0.380 0.620
I70 Atherosclerosis
0.000 0.380 0.620
I35 Nonrheumatic aortic valve disorders
0.000 0.385 0.615
I25.4 Coronary artery aneurysm
0.000 0.386 0.614
I24.1 Dressler's syndrome
0.000 0.392 0.608
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.394 0.606
Z95.3 Presence of xenogenic heart valve
0.000 0.396 0.604
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.396 0.604
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.396 0.604
I49 Other cardiac arrhythmias
0.000 0.405 0.595
I09 Other rheumatic heart diseases
0.000 0.410 0.590
I78 Diseases of capillaries
0.000 0.413 0.587
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.414 0.586
I35.0 Aortic (valve) stenosis
0.000 0.425 0.575
I77.8 Other specified disorders of arteries and arterioles
0.000 0.433 0.567
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.435 0.564
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.443 0.557
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.451 0.549
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.452 0.547
I79.1 Aortitis in diseases classified elsewhere
0.000 0.452 0.547
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.452 0.547
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.462 0.538
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.462 0.538
I72.2 Aneurysm of renal artery
0.000 0.462 0.538
I72.1 Aneurysm of artery of upper extremity
0.000 0.462 0.538
I49.0 Ventricular fibrillation and flutter
0.000 0.462 0.538
I74.8 Embolism and thrombosis of other arteries
0.000 0.470 0.530
I30 Acute pericarditis
0.000 0.471 0.529
I72.3 Aneurysm of iliac artery
0.000 0.473 0.527
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.484 0.516
I49.8 Other specified cardiac arrhythmias
0.000 0.486 0.514
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I72.9 Aneurysm of unspecified site
0.000 0.486 0.513
Z95.0 Presence of cardiac pacemaker
0.000 0.488 0.512
I51 Complications and ill-defined descriptions of heart disease
0.000 0.490 0.510
I02 Rheumatic chorea
0.000 0.496 0.503
I01 Rheumatic fever with heart involvement
0.000 0.496 0.503
I00 Rheumatic fever without mention of heart involvement
0.000 0.496 0.503
I71.0 Dissection of aorta [any part]
0.000 0.497 0.503
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.497 0.503
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.497 0.502
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.497 0.502
I44 Atrioventricular and left bundle-branch block
0.000 0.507 0.493
I77.6 Arteritis, unspecified
0.000 0.510 0.489
I52 Other heart disorders in diseases classified elsewhere
0.000 0.516 0.484
I48 Atrial fibrillation and flutter
0.000 0.516 0.484
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.516 0.484
I41 Myocarditis in diseases classified elsewhere
0.000 0.516 0.484
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.516 0.484
I32 Pericarditis in diseases classified elsewhere
0.000 0.516 0.484
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.517 0.483
I47 Paroxysmal tachycardia
0.000 0.520 0.480
I33 Acute and subacute endocarditis
0.000 0.521 0.479
I37 Pulmonary valve disorders
0.000 0.522 0.478
I49.9 Cardiac arrhythmia, unspecified
0.000 0.524 0.476
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.524 0.476
I99 Other and unspecified disorders of circulatory system
0.000 0.525 0.475
I07.1 Tricuspid insufficiency
0.000 0.527 0.473
I07.9 Tricuspid valve disease, unspecified
0.000 0.534 0.466
I07.8 Other tricuspid valve diseases
0.000 0.534 0.466
I07.2 Tricuspid stenosis with insufficiency
0.000 0.534 0.466
I07.0 Tricuspid stenosis
0.000 0.534 0.466
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.539 0.460
I06.8 Other rheumatic aortic valve diseases
0.000 0.539 0.460
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.539 0.460
I06.1 Rheumatic aortic insufficiency
0.000 0.539 0.460
I06.0 Rheumatic aortic stenosis
0.000 0.539 0.460
I49.4 Other and unspecified premature depolarisation
0.000 0.540 0.460
I40 Acute myocarditis
0.000 0.545 0.455
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.545 0.454
I72.8 Aneurysm of other specified arteries
0.000 0.547 0.453
I72.0 Aneurysm of carotid artery
0.000 0.550 0.450
I30.9 Acute pericarditis, unspecified
0.000 0.550 0.450
I36 Nonrheumatic tricuspid valve disorders
0.000 0.552 0.448
I70.9 Generalised and unspecified atherosclerosis
0.000 0.555 0.445
I70.8 Atherosclerosis of other arteries
0.000 0.555 0.445
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.558 0.441
I78.8 Other diseases of capillaries
0.000 0.569 0.431
I44.7 Left bundle-branch block, unspecified
0.000 0.570 0.430
I70.1 Atherosclerosis of renal artery
0.000 0.572 0.428
Z95.4 Presence of other heart-valve replacement
0.000 0.572 0.428
I49.2 Junctional premature depolarisation
0.000 0.573 0.427
I35.1 Aortic (valve) insufficiency
0.000 0.575 0.425
I24.8 Other forms of acute ischaemic heart disease
0.000 0.575 0.425
I09.8 Other specified rheumatic heart diseases
0.000 0.577 0.423
I09.2 Chronic rheumatic pericarditis
0.000 0.577 0.423
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.577 0.423
I09.0 Rheumatic myocarditis
0.000 0.577 0.423
I35.8 Other aortic valve disorders
0.000 0.577 0.422
I49.1 Atrial premature depolarisation
0.000 0.578 0.422
I78.9 Disease of capillaries, unspecified
0.000 0.579 0.421
I35.9 Aortic valve disorder, unspecified
0.000 0.580 0.420
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.584 0.416
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.587 0.413
I51.6 Cardiovascular disease, unspecified
0.000 0.591 0.409
I74.5 Embolism and thrombosis of iliac artery
0.000 0.596 0.404
I51.8 Other ill-defined heart diseases
0.000 0.602 0.398
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.613 0.387
I51.9 Heart disease, unspecified
0.000 0.614 0.386
I95 Hypotension
0.000 0.615 0.385
I70.0 Atherosclerosis of aorta
0.000 0.616 0.384
I51.0 Cardiac septal defect, acquired
0.000 0.620 0.380
I30.8 Other forms of acute pericarditis
0.000 0.621 0.379
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.621 0.379
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.626 0.374
I09.9 Rheumatic heart disease, unspecified
0.000 0.629 0.371
I51.5 Myocardial degeneration
0.000 0.634 0.366
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.634 0.366
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.634 0.366
I45 Other conduction disorders
0.000 0.636 0.364
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.639 0.361
I01.8 Other acute rheumatic heart disease
0.000 0.639 0.361
I01.2 Acute rheumatic myocarditis
0.000 0.639 0.361
I01.1 Acute rheumatic endocarditis
0.000 0.639 0.361
I01.0 Acute rheumatic pericarditis
0.000 0.639 0.361
I02.9 Rheumatic chorea without heart involvement
0.000 0.639 0.361
I02.0 Rheumatic chorea with heart involvement
0.000 0.639 0.361
I44.2 Atrioventricular block, complete
0.000 0.641 0.359
I44.3 Other and unspecified atrioventricular block
0.000 0.645 0.355
I44.5 Left posterior fascicular block
0.000 0.646 0.353
I44.4 Left anterior fascicular block
0.000 0.646 0.353
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.653 0.347
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.653 0.347
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.653 0.347
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.653 0.347
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.653 0.347
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.653 0.347
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.653 0.347
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.653 0.347
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.653 0.347
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.653 0.347
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.653 0.347
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.653 0.347
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.653 0.347
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.653 0.347
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.653 0.347
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.653 0.347
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.653 0.347
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.653 0.347
I48.4 Atypical atrial flutter
0.000 0.653 0.347
I48.3 Typical atrial flutter
0.000 0.653 0.347
I48.2 Chronic atrial fibrillation
0.000 0.653 0.347
I48.1 Persistent atrial fibrillation
0.000 0.653 0.347
I48.0 Paroxysmal atrial fibrillation
0.000 0.653 0.347
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.653 0.347
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.653 0.347
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.653 0.347
I47.1 Supraventricular tachycardia
0.000 0.656 0.344
I33.9 Acute endocarditis, unspecified
0.000 0.656 0.344
I37.9 Pulmonary valve disorder, unspecified
0.000 0.657 0.343
I37.8 Other pulmonary valve disorders
0.000 0.657 0.343
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.657 0.343
I37.0 Pulmonary valve stenosis
0.000 0.657 0.343
I44.6 Other and unspecified fascicular block
0.000 0.660 0.340
I33.0 Acute and subacute infective endocarditis
0.000 0.661 0.339
I28 Other diseases of pulmonary vessels
0.000 0.661 0.339
I37.1 Pulmonary valve insufficiency
0.000 0.662 0.338
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.664 0.336
I78.1 Naevus, nonneoplastic
0.000 0.666 0.334
I44.1 Atrioventricular block, second degree
0.000 0.666 0.334
I51.4 Myocarditis, unspecified
0.000 0.666 0.333
I45.2 Bifascicular block
0.000 0.667 0.333
I30.1 Infective pericarditis
0.000 0.668 0.332
I40.9 Acute myocarditis, unspecified
0.000 0.673 0.326
I40.8 Other acute myocarditis
0.000 0.673 0.326
I40.1 Isolated myocarditis
0.000 0.673 0.326
I47.2 Ventricular tachycardia
0.000 0.674 0.326
I47.0 Reentry ventricular arrhythmia
0.000 0.676 0.324
I31 Other diseases of pericardium
0.000 0.677 0.323
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.678 0.321
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.678 0.321
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.678 0.321
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.678 0.321
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.681 0.319
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.681 0.319
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.681 0.319
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.681 0.319
I46 Cardiac arrest
0.000 0.682 0.318
I95.2 Hypotension due to drugs
0.000 0.683 0.317
I95.1 Orthostatic hypotension
0.000 0.686 0.314
I49.3 Ventricular premature depolarisation
0.000 0.688 0.312
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.693 0.307
I40.0 Infective myocarditis
0.000 0.702 0.298
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.709 0.290
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.710 0.289
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.714 0.286
I26 Pulmonary embolism
0.000 0.714 0.286
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.715 0.284
I95.8 Other hypotension
0.000 0.721 0.279
I95.0 Idiopathic hypotension
0.000 0.723 0.277
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.724 0.276
I45.9 Conduction disorder, unspecified
0.000 0.725 0.275
I10-I15 Hypertensive diseases
0.000 0.725 0.275
I45.0 Right fascicular block
0.000 0.739 0.261
I45.8 Other specified conduction disorders
0.000 0.741 0.259
I34 Nonrheumatic mitral valve disorders
0.000 0.743 0.257
I05 Rheumatic mitral valve diseases
0.001 0.745 0.253
I44.0 Atrioventricular block, first degree
0.000 0.749 0.251
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.750 0.250
I27 Other pulmonary heart diseases
0.000 0.750 0.250
I49.5 Sick sinus syndrome
0.000 0.756 0.244
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.757 0.243
I28.1 Aneurysm of pulmonary artery
0.000 0.757 0.243
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.757 0.243
I28.8 Other specified diseases of pulmonary vessels
0.000 0.765 0.235
I31.8 Other specified diseases of pericardium
0.000 0.768 0.232
I31.2 Haemopericardium, not elsewhere classified
0.000 0.768 0.232
I31.1 Chronic constrictive pericarditis
0.000 0.768 0.232
I31.0 Chronic adhesive pericarditis
0.000 0.768 0.232
I46.1 Sudden cardiac death, so described
0.000 0.772 0.228
I45.6 Preexcitation syndrome
0.000 0.775 0.224
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.784 0.215
I45.5 Other specified heart block
0.000 0.788 0.212
I27.8 Other specified pulmonary heart diseases
0.000 0.790 0.210
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.791 0.209
I50 Heart failure
0.000 0.792 0.208
I15 Secondary hypertension
0.000 0.793 0.207
I31.3 Pericardial effusion (noninflammatory)
0.000 0.795 0.205
I45.3 Trifascicular block
0.000 0.795 0.205
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.796 0.204
I97.0 Postcardiotomy syndrome
0.000 0.796 0.204
I45.4 Nonspecific intraventricular block
0.000 0.800 0.200
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.802 0.197
I13 Hypertensive heart and renal disease
0.000 0.803 0.197
I46.9 Cardiac arrest, unspecified
0.000 0.803 0.197
I45.1 Other and unspecified right bundle-branch block
0.000 0.808 0.192
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.815 0.185
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.816 0.184
I05.8 Other mitral valve diseases
0.001 0.817 0.182
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.820 0.179
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.820 0.179
I98.0 Cardiovascular syphilis
0.000 0.820 0.179
I27.1 Kyphoscoliotic heart disease
0.000 0.821 0.179
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.823 0.177
I27.9 Pulmonary heart disease, unspecified
0.000 0.826 0.174
I51.7 Cardiomegaly
0.000 0.831 0.169
I05.2 Mitral stenosis with insufficiency
0.001 0.832 0.167
I97.1 Other functional disturbances following cardiac surgery
0.000 0.835 0.164
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.836 0.164
I12 Hypertensive renal disease
0.000 0.838 0.162
I11 Hypertensive heart disease
0.000 0.839 0.160
I15.1 Hypertension secondary to other renal disorders
0.000 0.841 0.159
I34.1 Mitral (valve) prolapse
0.000 0.848 0.152
I15.9 Seconday hypertension, unspecified
0.000 0.851 0.149
I15.8 Other secondary hypertension
0.000 0.851 0.149
I15.2 Hypertension secondary to endocrine disorders
0.000 0.851 0.149
I15.0 Renovascular hypertension
0.000 0.851 0.149
I27.2 Other secondary pulmonary hypertension
0.000 0.851 0.149
I50.1 Left ventricular failure
0.000 0.853 0.147
I05.0 Mitral stenosis
0.001 0.857 0.142
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.858 0.141
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.858 0.141
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.858 0.141
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.858 0.141
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.863 0.137
I31.9 Disease of pericardium, unspecified
0.000 0.871 0.128
I46.0 Cardiac arrest with successful resuscitation
0.000 0.872 0.128
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.001 0.873 0.126
I05.9 Mitral valve disease, unspecified
0.001 0.874 0.125
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.875 0.124
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.879 0.121
I12.0 Hypertensive renal disease with renal failure
0.000 0.882 0.118
I05.1 Rheumatic mitral insufficiency
0.002 0.883 0.116
I50.9 Heart failure, unspecified
0.000 0.909 0.091
I12.9 Hypertensive renal disease without renal failure
0.000 0.922 0.078
I11.9 Hypertensive heart disease without (congestive) heart failure
0.001 0.933 0.066
I34.0 Mitral (valve) insufficiency
0.000 0.934 0.066
I95.9 Hypotension, unspecified
0.000 0.935 0.065
I42 Cardiomyopathy
0.001 0.939 0.061
I27.0 Primary pulmonary hypertension
0.001 0.940 0.060
Y83.2 Surgical operation with anastomosis, bypass or graft
0.000 0.941 0.059
I50.0 Congestive heart failure
0.000 0.954 0.046
I42.7 Cardiomyopathy due to drugs and other external agents
0.001 0.956 0.044
I42.5 Other restrictive cardiomyopathy
0.001 0.956 0.044
I42.4 Endocardial fibroelastosis
0.001 0.956 0.044
I42.3 Endomyocardial (eosinophilic) disease
0.001 0.956 0.044
I42.8 Other cardiomyopathies
0.001 0.964 0.036
I42.2 Other hypertrophic cardiomyopathy
0.001 0.965 0.034
I42.0 Dilated cardiomyopathy
0.000 0.966 0.034
I42.1 Obstructive hypertrophic cardiomyopathy
0.001 0.967 0.032
I42.6 Alcoholic cardiomyopathy
0.001 0.967 0.032
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.000 0.970 0.030
I60-I69 Cerebrovascular diseases
0.001 0.972 0.027
I62 Other nontraumatic intracranial haemorrhage
0.000 0.976 0.024
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.977 0.023
O80.9 Single spontaneous delivery, unspecified
0.022 0.978 0.000
O80.0 Spontaneous vertex delivery
0.021 0.979 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.979 0.020
I68 Cerebrovascular disorders in diseases classified elsewhere
0.001 0.980 0.020
O80 Single spontaneous delivery
0.020 0.980 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.982 0.018
I62.1 Nontraumatic extradural haemorrhage
0.000 0.982 0.017
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.001 0.983 0.017
I42.9 Cardiomyopathy, unspecified
0.001 0.984 0.016
I65.2 Occlusion and stenosis of carotid artery
0.000 0.985 0.015
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.985 0.015
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.985 0.015
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.985 0.015
I65.1 Occlusion and stenosis of basilar artery
0.000 0.985 0.015
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.985 0.015
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.001 0.985 0.014
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.001 0.985 0.014
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.001 0.985 0.014
I68.0 Cerebral amyloid angiopathy
0.001 0.985 0.014
O80.1 Spontaneous breech delivery
0.015 0.985 0.000
E70-E90 Metabolic disorders
0.000 0.985 0.015
K85.9 Acute pancreatitis, unspecified
0.014 0.986 0.000
O80.8 Other single spontaneous delivery
0.014 0.986 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.001 0.986 0.013
K85 Acute pancreatitis
0.013 0.987 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.013 0.987 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.013 0.987 0.000
K85.1 Biliary acute pancreatitis
0.013 0.987 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.001 0.987 0.012
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.001 0.987 0.012
I66.3 Occlusion and stenosis of cerebellar arteries
0.001 0.987 0.012
I66.2 Occlusion and stenosis of posterior cerebral artery
0.001 0.987 0.012
I66.1 Occlusion and stenosis of anterior cerebral artery
0.001 0.987 0.012
I66.0 Occlusion and stenosis of middle cerebral artery
0.001 0.987 0.012
E85 Amyloidosis
0.000 0.987 0.012
I69 Sequelae of cerebrovascular disease
0.000 0.988 0.012
M13.9 Arthritis, unspecified
0.012 0.988 0.000
F10.3 Withdrawal state
0.000 0.988 0.012
F10.0 Acute intoxication
0.000 0.989 0.011
M13.94 Arthritis, unspecified (Hand)
0.011 0.989 0.000
E83.5 Disorders of calcium metabolism
0.000 0.989 0.011
M13.93 Arthritis, unspecified (Forearm)
0.011 0.989 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.011 0.989 0.000
E84 Cystic fibrosis
0.000 0.989 0.011
E79 Disorders of purine and pyrimidine metabolism
0.000 0.989 0.011
E77 Disorders of glycoprotein metabolism
0.000 0.989 0.011
E76 Disorders of glycosaminoglycan metabolism
0.000 0.989 0.011
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.989 0.011
E72 Other disorders of amino-acid metabolism
0.000 0.989 0.011
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.989 0.011
E70 Disorders of aromatic amino-acid metabolism
0.000 0.989 0.011
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.989 0.011
F10 Mental and behavioural disorders due to use of alcohol
0.000 0.989 0.011
E85.9 Amyloidosis, unspecified
0.000 0.989 0.011
E85.4 Organ-limited amyloidosis
0.000 0.990 0.010
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.010 0.990 0.000
E83 Disorders of mineral metabolism
0.000 0.990 0.010
I60 Subarachnoid haemorrhage
0.001 0.990 0.009
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.990 0.010
K85.8 Other acute pancreatitis
0.010 0.990 0.000
K85.3 Drug-induced acute pancreatitis
0.010 0.990 0.000
K85.0 Idiopathic acute pancreatitis
0.010 0.990 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.001 0.990 0.009
K85.2 Alcohol-induced acute pancreatitis
0.010 0.990 0.000
E73 Lactose intolerance
0.000 0.990 0.010
M13.92 Arthritis, unspecified (Upper arm)
0.010 0.990 0.000
F10.2 Dependence syndrome
0.000 0.990 0.010
I69.3 Sequelae of cerebral infarction
0.000 0.990 0.009
K82 Other diseases of gallbladder
0.010 0.990 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.991 0.009
K82.8 Other specified diseases of gallbladder
0.009 0.991 0.000
E85.8 Other amyloidosis
0.000 0.991 0.009
E85.3 Secondary systemic amyloidosis
0.000 0.991 0.009
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.991 0.009
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.991 0.009
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.991 0.009
K80 Cholelithiasis
0.009 0.991 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.009 0.991 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.991 0.009
F10.4 Withdrawal state with delirium
0.000 0.991 0.009
E88 Other metabolic disorders
0.000 0.991 0.009
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.991 0.008
M50.0 Cervical disk disorder with myelopathy
0.008 0.992 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.992 0.008
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.992 0.008
K80.4 Calculus of bile duct with cholecystitis
0.008 0.992 0.000
M50 Cervical disk disorders
0.008 0.992 0.000
F10.9 Unspecified mental and behavioural disorder
0.000 0.992 0.008
M50-M54 Other dorsopathies
0.008 0.992 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.992 0.008
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.992 0.008
E70.3 Albinism
0.000 0.992 0.008
E70.2 Disorders of tyrosine metabolism
0.000 0.992 0.008
E70.1 Other hyperphenylalaninaemias
0.000 0.992 0.008
E70.0 Classical phenylketonuria
0.000 0.992 0.008
E71.3 Disorders of fatty-acid metabolism
0.000 0.992 0.008
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.992 0.008
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.992 0.008
E71.0 Maple-syrup-urine disease
0.000 0.992 0.008
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.992 0.008
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.992 0.008
E72.5 Disorders of glycine metabolism
0.000 0.992 0.008
E72.4 Disorders of ornithine metabolism
0.000 0.992 0.008
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.992 0.008
E72.2 Disorders of urea cycle metabolism
0.000 0.992 0.008
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.992 0.008
E72.0 Disorders of amino-acid transport
0.000 0.992 0.008
E75.6 Lipid storage disorder, unspecified
0.000 0.992 0.008
E75.5 Other lipid storage disorders
0.000 0.992 0.008
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.992 0.008
E75.3 Sphingolipidosis, unspecified
0.000 0.992 0.008
E75.2 Other sphingolipidosis
0.000 0.992 0.008
E75.1 Other gangliosidosis
0.000 0.992 0.008
E75.0 GM2 gangliosidosis
0.000 0.992 0.008
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.992 0.008
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.992 0.008
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.992 0.008
E76.2 Other mucopolysaccharidoses
0.000 0.992 0.008
E76.1 Mucopolysaccharidosis, type II
0.000 0.992 0.008
E76.0 Mucopolysaccharidosis, type I
0.000 0.992 0.008
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.992 0.008
E77.8 Other disorders of glycoprotein metabolism
0.000 0.992 0.008
E77.1 Defects in glycoprotein degradation
0.000 0.992 0.008
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.992 0.008
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.992 0.008

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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