TreeWAS – Variant ID: rs2128739

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I20.9 Angina pectoris, unspecified	0.000	0.000	1.000
I25.2 Old myocardial infarction	0.000	0.000	1.000
I21 Acute myocardial infarction	0.000	0.002	0.998
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.006	0.994
I21.9 Acute myocardial infarction, unspecified	0.000	0.008	0.992
I22 Subsequent myocardial infarction	0.000	0.017	0.983
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.018	0.982
I20.1 Angina pectoris with documented spasm	0.000	0.044	0.956
Z95.1 Presence of aortocoronary bypass graft	0.000	0.045	0.955
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.056	0.944
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.066	0.934
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.083	0.917
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.084	0.916
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.087	0.913
I20.0 Unstable angina	0.000	0.111	0.889
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.113	0.887
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.151	0.849
I22.8 Subsequent myocardial infarction of other sites	0.000	0.159	0.841
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.180	0.820
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.210	0.790
I20.8 Other forms of angina pectoris	0.000	0.213	0.787
I25.6 Silent myocardial ischaemia	0.000	0.280	0.720
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.284	0.716
I25.3 Aneurysm of heart	0.000	0.284	0.716
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.347	0.653
I23 Certain current complications following acute myocardial infarction	0.000	0.390	0.610
Z95.3 Presence of xenogenic heart valve	0.000	0.399	0.601
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.422	0.578
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.440	0.560
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.562	0.437
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.562	0.437
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.562	0.437
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.562	0.437
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.562	0.437
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.562	0.437
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.562	0.437
I25.4 Coronary artery aneurysm	0.001	0.573	0.427
I21.4 Acute subendocardial myocardial infarction	0.000	0.662	0.338
I23.8 Other current complications following acute myocardial infarction	0.001	0.669	0.330
I25.5 Ischaemic cardiomyopathy	0.001	0.704	0.295
I24 Other acute ischaemic heart diseases	0.000	0.717	0.283
Z95.2 Presence of prosthetic heart valve	0.000	0.742	0.258
I24.1 Dressler's syndrome	0.000	0.788	0.212
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.826	0.174
Z95.4 Presence of other heart-valve replacement	0.000	0.844	0.156
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.877	0.123
Z95.0 Presence of cardiac pacemaker	0.000	0.893	0.107
I24.8 Other forms of acute ischaemic heart disease	0.000	0.929	0.071
Y45.0 Opioids and related analgesics	0.016	0.984	0.000
Z29.2 Other prophylactic chemotherapy	0.010	0.990	0.000
L93.0 Discoid lupus erythematosus	0.000	0.990	0.010
L08.8 Other specified local infections of skin and subcutaneous tissue	0.010	0.990	0.000
Q79.6 Ehlers-Danlos syndrome	0.008	0.991	0.000
Z83.3 Family history of diabetes mellitus	0.008	0.991	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.008	0.992	0.000
K29.5 Chronic gastritis, unspecified	0.000	0.992	0.008
Z83 Family history of other specific disorders	0.008	0.992	0.000
Q65 Congenital deformities of hip	0.008	0.992	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.008	0.992	0.000
Q65.8 Other congenital deformities of hip	0.008	0.992	0.000
Z83.5 Family history of eye and ear disorders	0.007	0.993	0.000
Z83.7 Family history of diseases of the digestive system	0.007	0.993	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.007	0.993	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.007	0.993	0.000
Q76 Congenital malformations of spine and bony thorax	0.007	0.993	0.000
U80.0 Penicillin resistant agent	0.000	0.993	0.007
Q79.1 Other congenital malformations of diaphragm	0.007	0.993	0.000
Z83.6 Family history of diseases of the respiratory system	0.007	0.993	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.007	0.993	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.007	0.993	0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.006	0.993	0.000
Q68 Other congenital musculoskeletal deformities	0.006	0.993	0.000
Q74 Other congenital malformations of limb(s)	0.006	0.994	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.994	0.006
Q65.9 Congenital deformity of hip, unspecified	0.006	0.994	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.006	0.994	0.000
Q79.5 Other congenital malformations of abdominal wall	0.006	0.994	0.000
Q79.4 Prune belly syndrome	0.006	0.994	0.000
Q79.3 Gastroschisis	0.006	0.994	0.000
Q79.2 Exomphalos	0.006	0.994	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.006	0.994	0.000
Q76.1 Klippel-Feil syndrome	0.006	0.994	0.000
Q79.0 Congenital diaphragmatic hernia	0.006	0.994	0.000
Z83.0 Family history of human immunodeficiency virus [HIV]	0.006	0.994	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.006	0.994	0.000
K13.0 Diseases of lips	0.000	0.994	0.006
Q65.6 Unstable hip	0.006	0.994	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.006	0.994	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.006	0.994	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.006	0.994	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.006	0.994	0.000
M19.98 Arthrosis, unspecified (Other)	0.000	0.994	0.006
Q75 Other congenital malformations of skull and face bones	0.006	0.994	0.000
Q73 Reduction defects of unspecified limb	0.006	0.994	0.000
Q72 Reduction defects of lower limb	0.006	0.994	0.000
Q71 Reduction defects of upper limb	0.006	0.994	0.000
Q70 Syndactyly	0.006	0.994	0.000
Q69 Polydactyly	0.006	0.994	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.006	0.994	0.000
Q78 Other osteochondrodysplasias	0.006	0.994	0.000
L93 Lupus erythematosus	0.000	0.994	0.006
Q67.6 Pectus excavatum	0.005	0.994	0.000
Q67.5 Congenital deformity of spine	0.005	0.994	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.005	0.994	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.005	0.994	0.000
Z83.1 Family history of other infectious and parasitic diseases	0.005	0.994	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.005	0.995	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.995	0.005
Q76.0 Spina bifida occulta	0.005	0.995	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.995	0.005
Q76.9 Congenital malformation of bony thorax, unspecified	0.005	0.995	0.000
Q76.8 Other congenital malformations of bony thorax	0.005	0.995	0.000
Q76.7 Congenital malformation of sternum	0.005	0.995	0.000
Q76.6 Other congenital malformations of ribs	0.005	0.995	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.005	0.995	0.000
Q76.2 Congenital spondylolisthesis	0.005	0.995	0.000
Y45.5 4-Aminophenol derivatives	0.005	0.995	0.000
L93.1 Subacute cutaneous lupus erythematosus	0.000	0.995	0.005
Q74.1 Congenital malformation of knee	0.005	0.995	0.000
Q67.8 Other congenital deformities of chest	0.005	0.995	0.000
Q67.7 Pectus carinatum	0.005	0.995	0.000
Q67.3 Plagiocephaly	0.005	0.995	0.000
Q67.2 Dolichocephaly	0.005	0.995	0.000
Q67.1 Compression facies	0.005	0.995	0.000
Q67.0 Facial asymmetry	0.005	0.995	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.005	0.995	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.005	0.995	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.005	0.995	0.000
Q68.4 Congenital bowing of tibia and fibula	0.005	0.995	0.000
Q68.3 Congenital bowing of femur	0.005	0.995	0.000
Q68.2 Congenital deformity of knee	0.005	0.995	0.000
Q68.1 Congenital deformity of hand	0.005	0.995	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.005	0.995	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.005	0.995	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.005	0.995	0.000
Q74.3 Arthrogryposis multiplex congenita	0.005	0.995	0.000
U80.1 Methicillin resistant agent	0.000	0.995	0.005
U80 Agent resistant to penicillin and related antibiotics	0.000	0.995	0.005
Q78.2 Osteopetrosis	0.004	0.995	0.000
Q77.4 Achondroplasia	0.004	0.995	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.995	0.005
Z90.5 Acquired absence of kidney	0.005	0.995	0.000
H11.0 Pterygium	0.005	0.995	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.004	0.995	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.995	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.004	0.995	0.000
Q77.6 Chondroectodermal dysplasia	0.004	0.995	0.000
Q77.5 Diastrophic dysplasia	0.004	0.995	0.000
Q77.3 Chondrodysplasia punctata	0.004	0.995	0.000
Q77.2 Short rib syndrome	0.004	0.995	0.000
Q77.1 Thanatophoric short stature	0.004	0.995	0.000
Q77.0 Achondrogenesis	0.004	0.995	0.000
Q69.9 Polydactyly, unspecified	0.004	0.995	0.000
Q69.2 Accessory toe(s)	0.004	0.995	0.000
Q69.1 Accessory thumb(s)	0.004	0.995	0.000
Q69.0 Accessory finger(s)	0.004	0.995	0.000
Q70.9 Syndactyly, unspecified	0.004	0.995	0.000
Q70.4 Polysyndactyly	0.004	0.995	0.000
Q70.3 Webbed toes	0.004	0.995	0.000
Q70.2 Fused toes	0.004	0.995	0.000
Q70.1 Webbed fingers	0.004	0.995	0.000
Q70.0 Fused fingers	0.004	0.995	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.004	0.995	0.000
Q71.8 Other reduction defects of upper limb(s)	0.004	0.995	0.000
Q71.6 Lobster-claw hand	0.004	0.995	0.000
Q71.5 Longitudinal reduction defect of ulna	0.004	0.995	0.000
Q71.4 Longitudinal reduction defect of radius	0.004	0.995	0.000
Q71.3 Congenital absence of hand and finger(s)	0.004	0.995	0.000
Q71.2 Congenital absence of both forearm and hand	0.004	0.995	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.004	0.995	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.004	0.995	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.004	0.995	0.000
Q72.8 Other reduction defects of lower limb(s)	0.004	0.995	0.000
Q72.7 Split foot	0.004	0.995	0.000
Q72.6 Longitudinal reduction defect of fibula	0.004	0.995	0.000
Q72.5 Longitudinal reduction defect of tibia	0.004	0.995	0.000
Q72.4 Longitudinal reduction defect of femur	0.004	0.995	0.000
Q72.3 Congenital absence of foot and toe(s)	0.004	0.995	0.000
Q72.2 Congenital absence of both lower leg and foot	0.004	0.995	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.004	0.995	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.004	0.995	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.004	0.995	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.004	0.995	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.004	0.995	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.004	0.995	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.004	0.995	0.000
Q75.5 Oculomandibular dysostosis	0.004	0.995	0.000
Q75.4 Mandibulofacial dysostosis	0.004	0.995	0.000
Q75.3 Macrocephaly	0.004	0.995	0.000
Q75.2 Hypertelorism	0.004	0.995	0.000
Q75.1 Craniofacial dysostosis	0.004	0.995	0.000
Q75.0 Craniosynostosis	0.004	0.995	0.000
Q76.5 Cervical rib	0.004	0.995	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.005	0.995	0.000
Z99.8 Dependence on other enabling machines and devices	0.004	0.996	0.000
L08 Other local infections of skin and subcutaneous tissue	0.004	0.996	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.004	0.996	0.000
Q78.8 Other specified osteochondrodysplasias	0.004	0.996	0.000
Q78.6 Multiple congenital exostoses	0.004	0.996	0.000
Q78.5 Metaphyseal dysplasia	0.004	0.996	0.000
Q78.4 Enchondromatosis	0.004	0.996	0.000
Q78.3 Progressive diaphyseal dysplasia	0.004	0.996	0.000
Q78.1 Polyostotic fibrous dysplasia	0.004	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.004	0.996	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.996	0.004
L93.2 Other local lupus erythematosus	0.000	0.996	0.004
Z29 Need for other prophylactic measures	0.004	0.996	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.996	0.004
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
Q78.0 Osteogenesis imperfecta	0.004	0.996	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.996	0.004
Y45.4 Antirheumatics	0.004	0.996	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.996	0.004
Y45.1 Salicylates	0.004	0.996	0.000
L71.9 Rosacea, unspecified	0.000	0.996	0.004
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.004	0.996	0.000
Y45.2 Propionic acid derivatives	0.004	0.996	0.000
Z29.1 Prophylactic immunotherapy	0.004	0.996	0.000
G97.8 Other postprocedural disorders of nervous system	0.000	0.996	0.004
K74.6 Other and unspecified cirrhosis of liver	0.000	0.996	0.004
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.004	0.996	0.000
L08.1 Erythrasma	0.003	0.997	0.000
H11.1 Conjunctival degenerations and deposits	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.000	0.997	0.003
H11 Other disorders of conjunctiva	0.003	0.997	0.000
K29.1 Other acute gastritis	0.003	0.997	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.997	0.003
Q39.4 Oesophageal web	0.003	0.997	0.000
Z29.9 Prophylactic measure, unspecified	0.003	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
E78.0 Pure hypercholesterolaemia	0.000	0.997	0.003
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
L08.0 Pyoderma	0.003	0.997	0.000
H35.8 Other specified retinal disorders	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Z29.0 Isolation	0.003	0.997	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
R45.8 Other symptoms and signs involving emotional state	0.000	0.997	0.003
H11.9 Disorder of conjunctiva, unspecified	0.003	0.997	0.000
Q66.7 Pes cavus	0.003	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.003	0.997	0.000
H11.8 Other specified disorders of conjunctiva	0.003	0.997	0.000
Q66.3 Other congenital varus deformities of feet	0.003	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.997	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.003	0.997	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.003	0.997	0.000
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.003	0.997	0.000
Y45.8 Other analgesics and antipyretics	0.002	0.997	0.000
Q66.5 Congenital pes planus	0.002	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.997	0.000
Q66.1 Talipes calcaneovarus	0.002	0.997	0.000
K83.0 Cholangitis	0.000	0.997	0.003
Q66.9 Congenital deformity of feet, unspecified	0.002	0.997	0.000
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
C48.0 Retroperitoneum	0.000	0.997	0.003
H35.4 Peripheral retinal degeneration	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
Q96 Turner's syndrome	0.003	0.997	0.000
H11.2 Conjunctival scars	0.002	0.997	0.000
Q05 Spina bifida	0.003	0.997	0.000
H54.4 Blindness, one eye	0.003	0.997	0.000
Q44.6 Cystic disease of liver	0.002	0.997	0.000
Q03 Congenital hydrocephalus	0.002	0.997	0.000
Z29.8 Other specified prophylactic measures	0.002	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.997	0.000
Q01 Encephalocele	0.002	0.997	0.000
Q00 Anencephaly and similar malformations	0.002	0.997	0.000
Q02 Microcephaly	0.002	0.997	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.002	0.997	0.000
S52.00 Fracture of upper end of ulna (closed)	0.002	0.998	0.000
C25.9 Pancreas, unspecified	0.000	0.998	0.002
Q66.0 Talipes equinovarus	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.002
H35.7 Separation of retinal layers	0.002	0.998	0.000
Q07.0 Arnold-Chiari syndrome	0.002	0.998	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.002	0.998	0.000
Q39.8 Other congenital malformations of oesophagus	0.002	0.998	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.998	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.998	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.998	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.998	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.998	0.000
Q96.9 Turner's syndrome, unspecified	0.002	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
Q07.8 Other specified congenital malformations of nervous system	0.002	0.998	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
Q30 Congenital malformations of nose	0.002	0.998	0.000
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
Q90 Down's syndrome	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q39.6 Diverticulum of oesophagus	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Q04.8 Other specified congenital malformations of brain	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.998	0.000
S42.40 Fracture of lower end of humerus (closed)	0.000	0.998	0.002
H66.9 Otitis media, unspecified	0.002	0.998	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.998	0.002
H11.3 Conjunctival haemorrhage	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.000	0.998	0.002
Q07.9 Congenital malformation of nervous system, unspecified	0.002	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.998	0.000
Q33 Congenital malformations of lung	0.002	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.002	0.998	0.000
H35 Other retinal disorders	0.002	0.998	0.000
Q87.4 Marfan's syndrome	0.002	0.998	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.998	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
C48.2 Peritoneum, unspecified	0.000	0.998	0.002
H11.4 Other conjunctival vascular disorders and cysts	0.002	0.998	0.000
H35.2 Other proliferative retinopathy	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.998	0.000
R01.1 Cardiac murmur, unspecified	0.000	0.998	0.002
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
Q85.1 Tuberous sclerosis	0.002	0.998	0.000
Q04.9 Congenital malformation of brain, unspecified	0.002	0.998	0.000
Q04.5 Megalencephaly	0.002	0.998	0.000
Q04.4 Septo-optic dysplasia	0.002	0.998	0.000
Q04.3 Other reduction deformities of brain	0.002	0.998	0.000
Q04.2 Holoprosencephaly	0.002	0.998	0.000
Q04.1 Arhinencephaly	0.002	0.998	0.000
Q04.0 Congenital malformations of corpus callosum	0.002	0.998	0.000
Q53.1 Undescended testicle, unilateral	0.002	0.998	0.000
Q96.8 Other variants of Turner's syndrome	0.002	0.998	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.002	0.998	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.002	0.998	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.002	0.998	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.002	0.998	0.000
Q96.0 Karyotype 45,X	0.002	0.998	0.000
G82.1 Spastic paraplegia	0.000	0.998	0.002
Q03.0 Malformations of aqueduct of Sylvius	0.002	0.998	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.002	0.998	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.002	0.998	0.000
Q98.7 Male with sex chromosome mosaicism	0.002	0.998	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.002	0.998	0.000
Q98.5 Karyotype 47,XYY	0.002	0.998	0.000
Q98.3 Other male with 46,XX karyotype	0.002	0.998	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.002	0.998	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.002	0.998	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.002	0.998	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.002	0.998	0.000
Q04.6 Congenital cerebral cysts	0.002	0.998	0.000
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.002	0.998	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.998	0.002
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.998	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.998	0.002
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.000	0.998	0.002
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.002	0.998	0.000
Q03.8 Other congenital hydrocephalus	0.002	0.998	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.002	0.998	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.002	0.998	0.000
Q53.9 Undescended testicle, unspecified	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.002
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.998	0.002
Q00.2 Iniencephaly	0.002	0.998	0.000
Q00.1 Craniorachischisis	0.002	0.998	0.000
Q00.0 Anencephaly	0.002	0.998	0.000
Q01.9 Encephalocele, unspecified	0.002	0.998	0.000
Q01.8 Encephalocele of other sites	0.002	0.998	0.000
Q01.2 Occipital encephalocele	0.002	0.998	0.000
Q01.1 Nasofrontal encephalocele	0.002	0.998	0.000
Q01.0 Frontal encephalocele	0.002	0.998	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.002	0.998	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.002	0.998	0.000
Q06.4 Hydromyelia	0.002	0.998	0.000
Q06.3 Other congenital cauda equina malformations	0.002	0.998	0.000
Q06.2 Diastematomyelia	0.002	0.998	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.002	0.998	0.000
Q06.0 Amyelia	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.998	0.000
Q44.2 Atresia of bile ducts	0.002	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.002	0.998	0.000
H35.9 Retinal disorder, unspecified	0.002	0.998	0.000
Q40.1 Congenital hiatus hernia	0.002	0.998	0.000
Q85.9 Phakomatosis, unspecified	0.002	0.998	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.998	0.002
Q31.0 Web of larynx	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.000	0.998	0.002
Q30.3 Congenital perforated nasal septum	0.002	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.998	0.000
C48.1 Specified parts of peritoneum	0.000	0.998	0.002
Q44.7 Other congenital malformations of liver	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
Q30.9 Congenital malformation of nose, unspecified	0.002	0.998	0.000
Q31.3 Laryngocele	0.002	0.998	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.998	0.000
Q91.7 Patau's syndrome, unspecified	0.002	0.998	0.000
Q91.6 Trisomy 13, translocation	0.002	0.998	0.000
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q91.4 Trisomy 13, meiotic nondisjunction	0.002	0.998	0.000
Q91.3 Edwards' syndrome, unspecified	0.002	0.998	0.000
Q91.2 Trisomy 18, translocation	0.002	0.998	0.000
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q91.0 Trisomy 18, meiotic nondisjunction	0.002	0.998	0.000
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.002	0.998	0.000
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.002	0.998	0.000
Q92.7 Triploidy and polyploidy	0.002	0.998	0.000
Q92.6 Extra marker chromosomes	0.002	0.998	0.000
Q92.5 Duplications with other complex rearrangements	0.002	0.998	0.000
Q92.4 Duplications seen only at prometaphase	0.002	0.998	0.000
Q92.3 Minor partial trisomy	0.002	0.998	0.000
Q92.2 Major partial trisomy	0.002	0.998	0.000
Q92.1 Whole chromosome trisomy, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q92.0 Whole chromosome trisomy, meiotic nondisjunction	0.002	0.998	0.000
Q93.9 Deletion from autosomes, unspecified	0.002	0.998	0.000
Q93.8 Other deletions from the autosomes	0.002	0.998	0.000
Q93.7 Deletions with other complex rearrangements	0.002	0.998	0.000
Q93.6 Deletions seen only at prometaphase	0.002	0.998	0.000
Q93.5 Other deletions of part of a chromosome	0.002	0.998	0.000
Q93.4 Deletion of short arm of chromosome 5	0.002	0.998	0.000
Q93.3 Deletion of short arm of chromosome 4	0.002	0.998	0.000
Q93.2 Chromosome replaced with ring or dicentric	0.002	0.998	0.000
Q93.1 Whole chromosome monosomy, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q93.0 Whole chromosome monosomy, meiotic nondisjunction	0.002	0.998	0.000
Q95.9 Balanced rearrangement and structural marker, unspecified	0.002	0.998	0.000
Q95.8 Other balanced rearrangements and structural markers	0.002	0.998	0.000
Q95.5 Individuals with autosomal fragile site	0.002	0.998	0.000
Q95.4 Individuals with marker heterochromatin	0.002	0.998	0.000
Q95.3 Balanced sex/autosomal rearrangement in abnormal individual	0.002	0.998	0.000
Q95.2 Balanced autosomal rearrangement in abnormal individual	0.002	0.998	0.000
Q95.1 Chromosome inversion in normal individual	0.002	0.998	0.000
Q95.0 Balanced translocation and insertion in normal individual	0.002	0.998	0.000
Q97.9 Sex chromosome abnormality, female phenotype, unspecified	0.002	0.998	0.000
Q97.8 Other specified sex chromosome abnormalities, female phenotype	0.002	0.998	0.000
Q97.3 Female with 46,XY karyotype	0.002	0.998	0.000
Q97.2 Mosaicism, lines with various numbers of X chromosomes	0.002	0.998	0.000
Q97.1 Female with more than three X chromosomes	0.002	0.998	0.000
Q97.0 Karyotype 47,XXX	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.002	0.998	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
T46.7 Peripheral vasodilators	0.000	0.998	0.002
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.998	0.002
Q54 Hypospadias	0.002	0.998	0.000
G24.9 Dystonia, unspecified	0.002	0.998	0.000
Q27.4 Congenital phlebectasia	0.002	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.998	0.000
Q30.8 Other congenital malformations of nose	0.002	0.998	0.000
Q30.2 Fissured, notched and cleft nose	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations