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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17628203
log Bayes Factor = 26.8212
Chromosome 6   position 161,682,569  (GRCh37) Explore rs17628203 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
1.000 0.000 0.000
E78.0 Pure hypercholesterolaemia
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.999 0.001 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.999 0.001 0.000
I25.2 Old myocardial infarction
0.999 0.001 0.000
E78.5 Hyperlipidaemia, unspecified
0.993 0.007 0.000
I20.0 Unstable angina
0.988 0.012 0.000
I77 Other disorders of arteries and arterioles
0.983 0.017 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.980 0.020 0.000
M45-M49 Spondylopathies
0.977 0.023 0.000
M20-M25 Other joint disorders
0.977 0.023 0.000
I35 Nonrheumatic aortic valve disorders
0.974 0.026 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.971 0.029 0.000
Z95.1 Presence of aortocoronary bypass graft
0.969 0.031 0.000
M05-M14 Inflammatory polyarthropathies
0.969 0.031 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.968 0.032 0.000
I51 Complications and ill-defined descriptions of heart disease
0.964 0.036 0.000
Chapter I Certain infectious and parasitic diseases
0.963 0.037 0.000
I10-I15 Hypertensive diseases
0.959 0.041 0.000
I74 Arterial embolism and thrombosis
0.951 0.049 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.951 0.049 0.000
M47 Spondylosis
0.945 0.055 0.000
I21 Acute myocardial infarction
0.944 0.056 0.000
I71 Aortic aneurysm and dissection
0.943 0.057 0.000
I50 Heart failure
0.940 0.060 0.000
M47.9 Spondylosis, unspecified
0.930 0.070 0.000
M06 Other rheumatoid arthritis
0.925 0.075 0.000
I10 Essential (primary) hypertension
0.923 0.077 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.922 0.078 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.922 0.078 0.000
Chapter XXI Factors influencing health status and contact with health services
0.918 0.082 0.000
E87.7 Fluid overload
0.917 0.083 0.000
M24 Other specific joint derangements
0.915 0.085 0.000
M45 Ankylosing spondylitis
0.914 0.086 0.000
Z95.0 Presence of cardiac pacemaker
0.912 0.088 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.911 0.089 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.909 0.091 0.000
E20-E35 Disorders of other endocrine glands
0.908 0.092 0.000
I24 Other acute ischaemic heart diseases
0.906 0.094 0.000
I35.0 Aortic (valve) stenosis
0.905 0.095 0.000
I51.8 Other ill-defined heart diseases
0.903 0.097 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.902 0.098 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.894 0.106 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.893 0.107 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.890 0.110 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.886 0.114 0.000
I77.1 Stricture of artery
0.879 0.121 0.000
M11 Other crystal arthropathies
0.877 0.123 0.000
Z95.2 Presence of prosthetic heart valve
0.872 0.127 0.000
A00-A09 Intestinal infectious diseases
0.872 0.128 0.000
I72 Other aneurysm
0.867 0.133 0.000
I50.9 Heart failure, unspecified
0.866 0.134 0.000
M35 Other systemic involvement of connective tissue
0.864 0.136 0.000
I77.6 Arteritis, unspecified
0.857 0.143 0.000
I20.8 Other forms of angina pectoris
0.854 0.146 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.854 0.146 0.000
I45 Other conduction disorders
0.853 0.147 0.000
I24.8 Other forms of acute ischaemic heart disease
0.851 0.149 0.000
M06.0 Seronegative rheumatoid arthritis
0.850 0.150 0.000
Chapter VIII Diseases of the ear and mastoid process
0.846 0.154 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.844 0.156 0.000
M23 Internal derangement of knee
0.843 0.157 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.843 0.157 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.843 0.157 0.000
M86-M90 Other osteopathies
0.842 0.158 0.000
I25.5 Ischaemic cardiomyopathy
0.842 0.158 0.000
I50.0 Congestive heart failure
0.835 0.165 0.000
I42 Cardiomyopathy
0.830 0.170 0.000
I46 Cardiac arrest
0.829 0.171 0.000
E87.5 Hyperkalaemia
0.828 0.172 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.827 0.173 0.000
Chapter VII Diseases of the eye and adnexa
0.825 0.175 0.000
M60-M63 Disorders of muscles
0.824 0.176 0.000
A04 Other bacterial intestinal infections
0.823 0.177 0.000
Z95.4 Presence of other heart-valve replacement
0.818 0.182 0.000
I20.1 Angina pectoris with documented spasm
0.817 0.183 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.817 0.183 0.000
M06.9 Rheumatoid arthritis, unspecified
0.816 0.184 0.000
I35.8 Other aortic valve disorders
0.816 0.184 0.000
E27 Other disorders of adrenal gland
0.814 0.186 0.000
M11.2 Other chondrocalcinosis
0.812 0.188 0.000
Chapter X Diseases of the respiratory system
0.809 0.191 0.000
I51.7 Cardiomegaly
0.809 0.191 0.000
Z72 Problems related to lifestyle
0.807 0.193 0.000
M21 Other acquired deformities of limbs
0.800 0.200 0.000
Z95.3 Presence of xenogenic heart valve
0.798 0.202 0.000
I74.8 Embolism and thrombosis of other arteries
0.796 0.204 0.000
M30 Polyarteritis nodosa and related conditions
0.795 0.205 0.000
I74.5 Embolism and thrombosis of iliac artery
0.793 0.207 0.000
E74 Other disorders of carbohydrate metabolism
0.792 0.207 0.000
Z72.0 Tobacco use
0.792 0.208 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.791 0.209 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.790 0.210 0.000
M91-M94 Chondropathies
0.789 0.211 0.000
Q60-Q64 Congenital malformations of the urinary system
0.788 0.212 0.000
M15-M19 Arthrosis
0.787 0.213 0.000
I31 Other diseases of pericardium
0.786 0.214 0.000
M33 Dermatopolymyositis
0.782 0.217 0.000
I05-I09 Chronic rheumatic heart diseases
0.781 0.219 0.000
M05 Seropositive rheumatoid arthritis
0.780 0.220 0.000
A04.8 Other specified bacterial intestinal infections
0.780 0.220 0.000
I33 Acute and subacute endocarditis
0.777 0.223 0.000
M24.1 Other articular cartilage disorders
0.776 0.224 0.000
M35.3 Polymyalgia rheumatica
0.775 0.225 0.000
I47 Paroxysmal tachycardia
0.774 0.226 0.000
A30-A49 Other bacterial diseases
0.774 0.226 0.000
H10-H13 Disorders of conjunctiva
0.774 0.226 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.772 0.227 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.767 0.233 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.766 0.234 0.000
I35.9 Aortic valve disorder, unspecified
0.765 0.235 0.000
B15-B19 Viral hepatitis
0.765 0.235 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.765 0.235 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.765 0.235 0.000
M14 Arthropathies in other diseases classified elsewhere
0.765 0.235 0.000
M24.0 Loose body in joint
0.765 0.235 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.764 0.236 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.762 0.238 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.761 0.239 0.000
I51.6 Cardiovascular disease, unspecified
0.761 0.239 0.000
B07 Viral warts
0.760 0.240 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.757 0.243 0.000
M00-M03 Infectious arthropathies
0.756 0.244 0.000
E78.2 Mixed hyperlipidaemia
0.756 0.244 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.755 0.245 0.000
J40-J47 Chronic lower respiratory diseases
0.755 0.245 0.000
M23.8 Other internal derangements of knee
0.749 0.251 0.000
I45.1 Other and unspecified right bundle-branch block
0.748 0.252 0.000
M25 Other joint disorders, not elsewhere classified
0.747 0.253 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.747 0.253 0.000
H65-H75 Diseases of middle ear and mastoid
0.745 0.255 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.745 0.255 0.000
I12 Hypertensive renal disease
0.743 0.257 0.000
E88 Other metabolic disorders
0.741 0.259 0.000
B99-B99 Other infectious diseases
0.739 0.261 0.000
B35-B49 Mycoses
0.738 0.262 0.000
I42.9 Cardiomyopathy, unspecified
0.737 0.263 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.737 0.263 0.000
E28 Ovarian dysfunction
0.737 0.263 0.000
H11 Other disorders of conjunctiva
0.734 0.266 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.732 0.268 0.000
H25-H28 Disorders of lens
0.731 0.269 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.731 0.269 0.000
J20-J22 Other acute lower respiratory infections
0.730 0.270 0.000
I77.8 Other specified disorders of arteries and arterioles
0.728 0.271 0.000
I72.4 Aneurysm of artery of lower extremity
0.728 0.272 0.000
I37 Pulmonary valve disorders
0.725 0.275 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.725 0.275 0.000
Z88.6 Personal history of allergy to analgesic agent
0.719 0.281 0.000
I46.0 Cardiac arrest with successful resuscitation
0.718 0.282 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.718 0.282 0.000
E78.6 Lipoprotein deficiency
0.717 0.283 0.000
E78.4 Other hyperlipidaemia
0.717 0.283 0.000
E78.3 Hyperchylomicronaemia
0.717 0.283 0.000
E78.1 Pure hyperglyceridaemia
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E85 Amyloidosis
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E73 Lactose intolerance
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.283 0.000
I48 Atrial fibrillation and flutter
0.716 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.283 0.000
I40 Acute myocarditis
0.716 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.283 0.000
E27.1 Primary adrenocortical insufficiency
0.716 0.284 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.716 0.284 0.000
M23.4 Loose body in knee
0.716 0.284 0.000
M18 Arthrosis of first carpometacarpal joint
0.713 0.287 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.711 0.289 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.708 0.292 0.000
M89 Other disorders of bone
0.706 0.293 0.000
E78.8 Other disorders of lipoprotein metabolism
0.706 0.294 0.000
A80-A89 Viral infections of the central nervous system
0.706 0.294 0.000
H25 Senile cataract
0.705 0.295 0.000
I77.5 Necrosis of artery
0.705 0.295 0.000
I77.4 Coeliac artery compression syndrome
0.705 0.295 0.000
I77.3 Arterial fibromuscular dysplasia
0.705 0.295 0.000
I77.2 Rupture of artery
0.705 0.295 0.000
I77.0 Arteriovenous fistula, acquired
0.705 0.295 0.000
I72.3 Aneurysm of iliac artery
0.704 0.296 0.000
I51.9 Heart disease, unspecified
0.704 0.296 0.000
H30-H36 Disorders of choroid and retina
0.703 0.297 0.000
E80.4 Gilbert's syndrome
0.703 0.297 0.000
J47 Bronchiectasis
0.702 0.298 0.000
M49 Spondylopathies in diseases classified elsewhere
0.701 0.299 0.000
H25.8 Other senile cataract
0.701 0.299 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.700 0.300 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.700 0.300 0.000
M32 Systemic lupus erythematosus
0.700 0.300 0.000
Q50-Q56 Congenital malformations of genital organs
0.699 0.301 0.000
M62 Other disorders of muscle
0.698 0.302 0.000
M12 Other specific arthropathies
0.694 0.305 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.694 0.305 0.000
M08 Juvenile arthritis
0.694 0.305 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.694 0.306 0.000
E87.4 Mixed disorder of acid-base balance
0.694 0.306 0.000
Q80-Q89 Other congenital malformations
0.692 0.307 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.692 0.308 0.000
I51.5 Myocardial degeneration
0.691 0.308 0.000
I51.4 Myocarditis, unspecified
0.691 0.308 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.691 0.308 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.691 0.308 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.691 0.308 0.000
I51.0 Cardiac septal defect, acquired
0.691 0.308 0.000
I15 Secondary hypertension
0.691 0.309 0.000
Chapter XXII Codes for special purposes
0.691 0.309 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.691 0.309 0.000
B65-B83 Helminthiases
0.691 0.309 0.000
B50-B64 Protozoal diseases
0.691 0.309 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.691 0.309 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.691 0.309 0.000
A75-A79 Rickettsioses
0.691 0.309 0.000
A70-A74 Other diseases caused by chlamydiae
0.691 0.309 0.000
A65-A69 Other spirochaetal diseases
0.691 0.309 0.000
A20-A28 Certain zoonotic bacterial diseases
0.691 0.309 0.000
A15-A19 Tuberculosis
0.691 0.309 0.000
E22 Hyperfunction of pituitary gland
0.690 0.310 0.000
I30 Acute pericarditis
0.689 0.311 0.000
Z72.2 Drug use
0.689 0.311 0.000
I13 Hypertensive heart and renal disease
0.688 0.312 0.000
I11 Hypertensive heart disease
0.687 0.313 0.000
I25.3 Aneurysm of heart
0.687 0.313 0.000
A04.5 Campylobacter enteritis
0.684 0.316 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.682 0.318 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.682 0.318 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.682 0.318 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.681 0.318 0.000
E87.3 Alkalosis
0.680 0.320 0.000
M80-M85 Disorders of bone density and structure
0.679 0.321 0.000
I31.3 Pericardial effusion (noninflammatory)
0.679 0.321 0.000
I47.2 Ventricular tachycardia
0.678 0.322 0.000
M19 Other arthrosis
0.678 0.322 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.678 0.322 0.000
M47.1 Other spondylosis with myelopathy
0.677 0.322 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.677 0.322 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.677 0.323 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.677 0.323 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.677 0.323 0.000
H60-H62 Diseases of external ear
0.676 0.324 0.000
Z84 Family history of other conditions
0.676 0.324 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.676 0.324 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.676 0.324 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.676 0.324 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.676 0.324 0.000
M23.9 Internal derangement of knee, unspecified
0.676 0.324 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.674 0.325 0.000
J22 Unspecified acute lower respiratory infection
0.673 0.327 0.000
M87 Osteonecrosis
0.672 0.328 0.000
I71.0 Dissection of aorta [any part]
0.671 0.329 0.000
M31 Other necrotising vasculopathies
0.671 0.329 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.671 0.329 0.000
E87.6 Hypokalaemia
0.669 0.331 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.669 0.331 0.000
E40-E46 Malnutrition
0.669 0.331 0.000
B25-B34 Other viral diseases
0.668 0.331 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.668 0.332 0.000
M34 Systemic sclerosis
0.668 0.332 0.000
E29 Testicular dysfunction
0.668 0.332 0.000
J09-J18 Influenza and pneumonia
0.667 0.333 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.667 0.333 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.667 0.333 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.667 0.333 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.667 0.333 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.667 0.333 0.000
I45.6 Preexcitation syndrome
0.666 0.334 0.000
M21.3 Wrist or foot drop (acquired)
0.666 0.334 0.000
I22 Subsequent myocardial infarction
0.665 0.335 0.000
I70 Atherosclerosis
0.664 0.335 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.664 0.336 0.000
M06.8 Other specified rheumatoid arthritis
0.663 0.337 0.000
M06.4 Inflammatory polyarthropathy
0.663 0.337 0.000
M06.3 Rheumatoid nodule
0.663 0.337 0.000
M06.2 Rheumatoid bursitis
0.663 0.337 0.000
M06.1 Adult-onset Still's disease
0.663 0.337 0.000
M24.2 Disorder of ligament
0.663 0.337 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.661 0.339 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.661 0.339 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.661 0.339 0.000
Z82.2 Family history of deafness and hearing loss
0.661 0.339 0.000
Z82.1 Family history of blindness and visual loss
0.661 0.339 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.661 0.339 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.661 0.339 0.000
Q35-Q37 Cleft lip and cleft palate
0.661 0.339 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.661 0.339 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.661 0.339 0.000
Q00-Q07 Congenital malformations of the nervous system
0.661 0.339 0.000
M24.02 Loose body in joint (Upper arm)
0.657 0.343 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.656 0.344 0.000
E23 Hypofunction and other disorders of pituitary gland
0.656 0.344 0.000
M24.9 Joint derangement, unspecified
0.656 0.344 0.000
M24.7 Protrusio acetabuli
0.656 0.344 0.000
M24.6 Ankylosis of joint
0.656 0.344 0.000
M24.5 Contracture of joint
0.656 0.344 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.656 0.344 0.000
Q23 Congenital malformations of aortic and mitral valves
0.655 0.345 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.655 0.345 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.655 0.345 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.655 0.345 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.655 0.345 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.655 0.345 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.655 0.345 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.655 0.345 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.655 0.345 0.000
I83 Varicose veins of lower extremities
0.654 0.346 0.000
H71 Cholesteatoma of middle ear
0.653 0.347 0.000
I12.9 Hypertensive renal disease without renal failure
0.652 0.348 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.652 0.348 0.000
I21.4 Acute subendocardial myocardial infarction
0.651 0.349 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.651 0.349 0.000
E34 Other endocrine disorders
0.651 0.349 0.000
E32 Diseases of thymus
0.651 0.349 0.000
E31 Polyglandular dysfunction
0.651 0.349 0.000
E30 Disorders of puberty, not elsewhere classified
0.651 0.349 0.000
E26 Hyperaldosteronism
0.651 0.349 0.000
E25 Adrenogenital disorders
0.651 0.349 0.000
E24 Cushing's syndrome
0.651 0.349 0.000
E20 Hypoparathyroidism
0.651 0.349 0.000
M40-M43 Deforming dorsopathies
0.651 0.349 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.651 0.349 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.650 0.350 0.000
I24.1 Dressler's syndrome
0.650 0.350 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.649 0.351 0.000
Z81 Family history of mental and behavioural disorders
0.649 0.351 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.648 0.352 0.000
A46 Erysipelas
0.647 0.353 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.647 0.353 0.000
I78 Diseases of capillaries
0.646 0.354 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.646 0.354 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.646 0.354 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.645 0.355 0.000
Chapter XX External causes of morbidity and mortality
0.644 0.356 0.000
Q61 Cystic kidney disease
0.644 0.356 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.644 0.356 0.000
M33.1 Other dermatomyositis
0.643 0.357 0.000
M35.0 Sicca syndrome [Sjogren]
0.643 0.357 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.641 0.359 0.000
I45.5 Other specified heart block
0.640 0.359 0.000
Q63 Other congenital malformations of kidney
0.640 0.360 0.000
M93 Other osteochondropathies
0.640 0.360 0.000
H35 Other retinal disorders
0.639 0.361 0.000
Z89 Acquired absence of limb
0.637 0.362 0.000
I85 Oesophageal varices
0.636 0.363 0.000
O60-O75 Complications of labour and delivery
0.636 0.364 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.635 0.365 0.000
M07 Psoriatic and enteropathic arthropathies
0.634 0.365 0.000
M25.8 Other specified joint disorders
0.632 0.368 0.000
M47.2 Other spondylosis with radiculopathy
0.631 0.368 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.631 0.369 0.000
M10 Gout
0.631 0.369 0.000
A02 Other Salmonella infections
0.631 0.369 0.000
M11.9 Crystal arthropathy, unspecified
0.629 0.371 0.000
M11.8 Other specified crystal arthropathies
0.629 0.371 0.000
M11.1 Familial chondrocalcinosis
0.629 0.371 0.000
M11.0 Hydroxyapatite deposition disease
0.629 0.371 0.000
E65-E68 Obesity and other hyperalimentation
0.628 0.372 0.000
H11.9 Disorder of conjunctiva, unspecified
0.627 0.373 0.000
A07 Other protozoal intestinal diseases
0.625 0.375 0.000
A06 Amoebiasis
0.625 0.375 0.000
A05 Other bacterial foodborne intoxications
0.625 0.375 0.000
A03 Shigellosis
0.625 0.375 0.000
A01 Typhoid and paratyphoid fevers
0.625 0.375 0.000
A00 Cholera
0.625 0.375 0.000
I08 Multiple valve diseases
0.625 0.375 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.625 0.375 0.000
M23.49 Loose body in knee-Unspec lig/men
0.625 0.375 0.000
B18 Chronic viral hepatitis
0.623 0.377 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.622 0.378 0.000
I72.9 Aneurysm of unspecified site
0.622 0.378 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.622 0.378 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.622 0.378 0.000
I72.2 Aneurysm of renal artery
0.622 0.378 0.000
I72.1 Aneurysm of artery of upper extremity
0.622 0.378 0.000
I72.0 Aneurysm of carotid artery
0.622 0.378 0.000
E28.3 Primary ovarian failure
0.621 0.379 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.620 0.380 0.000
M35.8 Other specified systemic involvement of connective tissue
0.620 0.380 0.000
M35.7 Hypermobility syndrome
0.620 0.380 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.620 0.380 0.000
M35.5 Multifocal fibrosclerosis
0.620 0.380 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.620 0.380 0.000
M35.2 Behcet's disease
0.620 0.380 0.000
M35.1 Other overlap syndromes
0.620 0.380 0.000
I05 Rheumatic mitral valve diseases
0.619 0.381 0.000
M14.6 Neuropathic arthropathy
0.619 0.381 0.000
I33.0 Acute and subacute infective endocarditis
0.618 0.382 0.000
M22 Disorders of patella
0.617 0.382 0.000
I87 Other disorders of veins
0.617 0.383 0.000
A49 Bacterial infection of unspecified site
0.617 0.383 0.000
I38 Endocarditis, valve unspecified
0.617 0.383 0.000
B00 Herpesviral [herpes simplex] infections
0.617 0.383 0.000
I72.8 Aneurysm of other specified arteries
0.616 0.384 0.000
M46 Other inflammatory spondylopathies
0.615 0.384 0.000
B44 Aspergillosis
0.615 0.385 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.615 0.385 0.000
J46 Status asthmaticus
0.615 0.385 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.615 0.385 0.000
I34 Nonrheumatic mitral valve disorders
0.614 0.386 0.000
I45.8 Other specified conduction disorders
0.612 0.388 0.000
I45.4 Nonspecific intraventricular block
0.612 0.388 0.000
I45.3 Trifascicular block
0.612 0.388 0.000
I45.2 Bifascicular block
0.612 0.388 0.000
I45.0 Right fascicular block
0.612 0.388 0.000
Z63 Other problems related to primary support group, including family circumstances
0.612 0.388 0.000
J42 Unspecified chronic bronchitis
0.611 0.389 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.610 0.390 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.610 0.390 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.610 0.390 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.610 0.390 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.610 0.390 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.610 0.390 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.610 0.390 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.610 0.390 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.609 0.391 0.000
Z76 Persons encountering health services in other circumstances
0.608 0.392 0.000
M62.8 Other specified disorders of muscle
0.608 0.392 0.000
M88 Paget's disease of bone [osteitis deformans]
0.607 0.393 0.000
J40 Bronchitis, not specified as acute or chronic
0.607 0.393 0.000
B06 Rubella [German measles]
0.605 0.394 0.000
B05 Measles
0.605 0.394 0.000
B01 Varicella [chickenpox]
0.605 0.394 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.605 0.394 0.000
B04 Monkeypox
0.605 0.394 0.000
B03 Smallpox
0.605 0.394 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.605 0.395 0.000
Z94 Transplanted organ and tissue status
0.605 0.395 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.604 0.396 0.000
M23.5 Chronic instability of knee
0.604 0.396 0.000
M23.1 Discoid meniscus (congenital)
0.604 0.396 0.000
M23.0 Cystic meniscus
0.604 0.396 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.604 0.396 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.604 0.396 0.000
M90 Osteopathies in diseases classified elsewhere
0.604 0.396 0.000
H11.3 Conjunctival haemorrhage
0.604 0.396 0.000
H55-H59 Other disorders of eye and adnexa
0.603 0.396 0.000
A40 Streptococcal septicaemia
0.603 0.397 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.601 0.399 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.600 0.400 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.599 0.401 0.000
M21.1 Varus deformity, not elsewhere classified
0.599 0.401 0.000
M47.8 Other spondylosis
0.598 0.402 0.000
J18 Pneumonia, organism unspecified
0.597 0.403 0.000
I42.8 Other cardiomyopathies
0.595 0.405 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.595 0.405 0.000
I42.6 Alcoholic cardiomyopathy
0.595 0.405 0.000
I42.5 Other restrictive cardiomyopathy
0.595 0.405 0.000
I42.4 Endocardial fibroelastosis
0.595 0.405 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.595 0.405 0.000
M19.0 Primary arthrosis of other joints
0.595 0.405 0.000
I46.1 Sudden cardiac death, so described
0.594 0.406 0.000
H66 Suppurative and unspecified otitis media
0.594 0.406 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.593 0.407 0.000
E80.6 Other disorders of bilirubin metabolism
0.593 0.407 0.000
E80.5 Crigler-Najjar syndrome
0.593 0.407 0.000
E80.3 Defects of catalase and peroxydase
0.593 0.407 0.000
E80.2 Other porphyria
0.593 0.407 0.000
E80.1 Porphyria cutanea tarda
0.593 0.407 0.000
E80.0 Hereditary erythropoietic porphyria
0.593 0.407 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.591 0.409 0.000
M61 Calcification and ossification of muscle
0.591 0.409 0.000
M60 Myositis
0.591 0.409 0.000
A08 Viral and other specified intestinal infections
0.590 0.409 0.000
I21.9 Acute myocardial infarction, unspecified
0.590 0.410 0.000
A04.9 Bacterial intestinal infection, unspecified
0.590 0.410 0.000
A04.6 Enteritis due to Yersinia enterocolitica
0.590 0.410 0.000
A04.4 Other intestinal Escherichia coli infections
0.590 0.410 0.000
A04.3 Enterohaemorrhagic Escherichia coli infection
0.590 0.410 0.000
A04.2 Enteroinvasive Escherichia coli infection
0.590 0.410 0.000
A04.1 Enterotoxigenic Escherichia coli infection
0.590 0.410 0.000
A04.0 Enteropathogenic Escherichia coli infection
0.590 0.410 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.590 0.410 0.000
H90-H95 Other disorders of ear
0.588 0.412 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.585 0.415 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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