TreeWAS – Variant ID: rs8023822

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20 Angina pectoris	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	0.999	0.001	0.000
I20.9 Angina pectoris, unspecified	0.997	0.003	0.000
I20.8 Other forms of angina pectoris	0.987	0.013	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.980	0.020	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.885	0.115	0.000
I25.2 Old myocardial infarction	0.868	0.132	0.000
I20.1 Angina pectoris with documented spasm	0.865	0.135	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.834	0.166	0.000
I20.0 Unstable angina	0.769	0.231	0.000
I23 Certain current complications following acute myocardial infarction	0.758	0.242	0.000
I24 Other acute ischaemic heart diseases	0.754	0.246	0.000
I25.4 Coronary artery aneurysm	0.750	0.250	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
I21 Acute myocardial infarction	0.685	0.315	0.000
I21.9 Acute myocardial infarction, unspecified	0.666	0.334	0.000
I22 Subsequent myocardial infarction	0.648	0.352	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.617	0.383	0.000
I24.1 Dressler's syndrome	0.609	0.390	0.000
I23.8 Other current complications following acute myocardial infarction	0.585	0.415	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.558	0.442	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.554	0.446	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.544	0.456	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.544	0.456	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.544	0.456	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.544	0.456	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.544	0.456	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.544	0.456	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.544	0.456	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.543	0.457	0.000
I25.3 Aneurysm of heart	0.514	0.486	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.491	0.509	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.427	0.573	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.401	0.599	0.000
I22.8 Subsequent myocardial infarction of other sites	0.390	0.610	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.389	0.611	0.000
I25.5 Ischaemic cardiomyopathy	0.371	0.629	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.364	0.635	0.000
I24.8 Other forms of acute ischaemic heart disease	0.346	0.654	0.000
I21.4 Acute subendocardial myocardial infarction	0.234	0.766	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.144	0.856	0.000
N81.2 Incomplete uterovaginal prolapse	0.034	0.966	0.000
N81 Female genital prolapse	0.033	0.967	0.000
N81.6 Rectocele	0.032	0.968	0.000
N81.5 Vaginal enterocele	0.031	0.969	0.000
N81.8 Other female genital prolapse	0.030	0.970	0.000
N81.9 Female genital prolapse, unspecified	0.028	0.972	0.000
N81.0 Female urethrocele	0.024	0.976	0.000
N81.3 Complete uterovaginal prolapse	0.024	0.976	0.000
N81.1 Cystocele	0.017	0.983	0.000
M35.0 Sicca syndrome [Sjogren]	0.015	0.985	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.012	0.987	0.001
M35 Other systemic involvement of connective tissue	0.013	0.987	0.000
M35.7 Hypermobility syndrome	0.012	0.988	0.000
L53.9 Erythematous condition, unspecified	0.000	0.989	0.011
M35.1 Other overlap syndromes	0.011	0.989	0.000
H04.2 Epiphora	0.010	0.990	0.000
M35.3 Polymyalgia rheumatica	0.010	0.990	0.000
I84.4 External haemorrhoids with other complications	0.010	0.990	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.009	0.991	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.009	0.991	0.000
M35.5 Multifocal fibrosclerosis	0.009	0.991	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.009	0.991	0.000
M35.2 Behcet's disease	0.009	0.991	0.000
M35.8 Other specified systemic involvement of connective tissue	0.009	0.991	0.000
N81.4 Uterovaginal prolapse, unspecified	0.007	0.993	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.007	0.993	0.000
C53.9 Cervix uteri, unspecified	0.000	0.993	0.007
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.994	0.006
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.006	0.994	0.000
J15.1 Pneumonia due to Pseudomonas	0.006	0.994	0.000
O80.9 Single spontaneous delivery, unspecified	0.006	0.994	0.000
S92.00 Fracture of calcaneus (closed)	0.006	0.994	0.000
L53 Other erythematous conditions	0.000	0.994	0.006
Z95.1 Presence of aortocoronary bypass graft	0.006	0.994	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.006	0.994	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.995	0.005
J15 Bacterial pneumonia, not elsewhere classified	0.005	0.995	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.995	0.005
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.005	0.995	0.000
S92.0 Fracture of calcaneus	0.005	0.995	0.000
H04.8 Other disorders of lachrymal system	0.005	0.995	0.000
J15.9 Bacterial pneumonia, unspecified	0.005	0.995	0.000
H04 Disorders of lachrymal system	0.005	0.995	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.005	0.995	0.000
N30.8 Other cystitis	0.005	0.995	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.004	0.995	0.000
Z71.3 Dietary counselling and surveillance	0.000	0.996	0.004
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.996	0.004
L53.3 Other chronic figurate erythema	0.000	0.996	0.004
L53.2 Erythema marginatum	0.000	0.996	0.004
L53.1 Erythema annulare centrifugum	0.000	0.996	0.004
N76.2 Acute vulvitis	0.000	0.996	0.004
S92 Fracture of foot, except ankle	0.004	0.996	0.000
L53.8 Other specified erythematous conditions	0.000	0.996	0.004
H04.9 Disorder of lachrymal system, unspecified	0.004	0.996	0.000
H04.4 Chronic inflammation of lachrymal passages	0.004	0.996	0.000
J15.3 Pneumonia due to streptococcus, group B	0.004	0.996	0.000
F60.9 Personality disorder, unspecified	0.004	0.996	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.004	0.996	0.000
L53.0 Toxic erythema	0.000	0.996	0.004
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.996	0.004
J15.8 Other bacterial pneumonia	0.004	0.996	0.000
C53 Malignant neoplasm of cervix uteri	0.000	0.996	0.004
S92.5 Fracture of other toe	0.004	0.996	0.000
S92.01 Fracture of calcaneus (open)	0.004	0.996	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.996	0.004
J15.5 Pneumonia due to Escherichia coli	0.004	0.996	0.000
J15.2 Pneumonia due to staphylococcus	0.004	0.996	0.000
S92.2 Fracture of other tarsal bone(s)	0.004	0.996	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.996	0.004
H04.6 Other changes in lachrymal passages	0.004	0.996	0.000
H04.0 Dacryoadenitis	0.004	0.996	0.000
S92.4 Fracture of great toe	0.004	0.996	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.996	0.004
S92.40 Fracture of great toe (closed)	0.003	0.996	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.003	0.996	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.003	0.996	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.003	0.996	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.003	0.996	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.996	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.003	0.996	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.003	0.996	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.003	0.996	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.003	0.996	0.000
S92.1 Fracture of talus	0.003	0.997	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.997	0.003
S92.20 Fracture of other tarsal bone(s) (closed)	0.003	0.997	0.000
S92.51 Fracture of other toe (open)	0.003	0.997	0.000
C53.0 Endocervix	0.000	0.997	0.003
J15.4 Pneumonia due to other streptococci	0.003	0.997	0.000
Z95.3 Presence of xenogenic heart valve	0.003	0.997	0.000
L03.3 Cellulitis of trunk	0.003	0.997	0.000
S02.50 Fracture of tooth (closed)	0.003	0.997	0.000
S92.9 Fracture of foot, unspecified	0.003	0.997	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.997	0.003
S92.7 Multiple fractures of foot	0.003	0.997	0.000
S92.50 Fracture of other toe (closed)	0.003	0.997	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.997	0.003
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.997	0.003
C34.3 Lower lobe, bronchus or lung	0.000	0.997	0.003
M80 Osteoporosis with pathological fracture	0.003	0.997	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.997	0.003
N76.0 Acute vaginitis	0.000	0.997	0.003
S92.3 Fracture of metatarsal bone	0.003	0.997	0.000
C53.8 Overlapping lesion of cervix uteri	0.000	0.997	0.003
C53.1 Exocervix	0.000	0.997	0.003
Z30.1 Insertion of (intra-uterine) contraceptive device	0.000	0.997	0.003
N76 Other inflammation of vagina and vulva	0.000	0.997	0.003
M80.9 Unspecified osteoporosis with pathological fracture	0.003	0.997	0.000
O75.8 Other specified complications of labour and delivery	0.000	0.997	0.003
S92.21 Fracture of other tarsal bone(s) (open)	0.003	0.997	0.000
K86.2 Cyst of pancreas	0.000	0.997	0.003
H04.1 Other disorders of lachrymal gland	0.003	0.997	0.000
S92.10 Fracture of talus (closed)	0.003	0.997	0.000
L91.0 Keloid scar	0.000	0.997	0.003
T83.2 Mechanical complication of graft of urinary organ	0.000	0.997	0.003
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
N76.6 Ulceration of vulva	0.000	0.997	0.003
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.997	0.003
S92.11 Fracture of talus (open)	0.003	0.997	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.997	0.003
N76.1 Subacute and chronic vaginitis	0.000	0.997	0.003
S92.91 Fracture of foot, unspecified (open)	0.002	0.997	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.997	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.003	0.997	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.003	0.997	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.003	0.997	0.000
S92.71 Multiple fractures of foot (open)	0.002	0.997	0.000
D75.2 Essential thrombocytosis	0.000	0.997	0.003
I49.5 Sick sinus syndrome	0.000	0.997	0.003
K86.8 Other specified diseases of pancreas	0.000	0.997	0.003
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.002	0.997	0.000
S92.41 Fracture of great toe (open)	0.002	0.997	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
S92.70 Multiple fractures of foot (closed)	0.002	0.997	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.002	0.997	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.002	0.997	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.002	0.997	0.000
O82.1 Delivery by emergency Caesarean section	0.003	0.997	0.000
N71.1 Chronic inflammatory disease of uterus	0.000	0.997	0.003
S92.31 Fracture of metatarsal bone (open)	0.002	0.997	0.000
N76.5 Ulceration of vagina	0.000	0.997	0.002
N71 Inflammatory disease of uterus, except cervix	0.000	0.997	0.003
L50-L54 Urticaria and erythema	0.000	0.997	0.003
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.002	0.997	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.997	0.003
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.997	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.997	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.997	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.997	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.997	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.997	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.997	0.003
K86.1 Other chronic pancreatitis	0.000	0.997	0.003
Z11.2 Special screening examination for other bacterial diseases	0.000	0.998	0.002
H04.5 Stenosis and insufficiency of lachrymal passages	0.002	0.998	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.002	0.998	0.000
O80 Single spontaneous delivery	0.002	0.998	0.000
D75.1 Secondary polycythaemia	0.000	0.998	0.002
M80.8 Other osteoporosis with pathological fracture	0.002	0.998	0.000
K86 Other diseases of pancreas	0.000	0.998	0.002
R45.8 Other symptoms and signs involving emotional state	0.002	0.998	0.000
I49.4 Other and unspecified premature depolarisation	0.000	0.998	0.002
L50.1 Idiopathic urticaria	0.000	0.998	0.002
S99.9 Unspecified injury of ankle and foot	0.002	0.998	0.000
N76.4 Abscess of vulva	0.000	0.998	0.002
L50 Urticaria	0.000	0.998	0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
L50.0 Allergic urticaria	0.000	0.998	0.002
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
D75.0 Familial erythrocytosis	0.000	0.998	0.002
L03.8 Cellulitis of other sites	0.002	0.998	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.998	0.002
J92.0 Pleural plaque with presence of asbestos	0.000	0.998	0.002
N18.3 Chronic kidney disease, stage 3	0.000	0.998	0.002
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
W07.0 Home	0.002	0.998	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.002	0.998	0.000
L51 Erythema multiforme	0.000	0.998	0.002
T85.4 Mechanical complication of breast prosthesis and implant	0.002	0.998	0.000
J80 Adult respiratory distress syndrome	0.002	0.998	0.000
I46.0 Cardiac arrest with successful resuscitation	0.000	0.998	0.002
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.002	0.998	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.002	0.998	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.002	0.998	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.002	0.998	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
D37.4 Colon	0.000	0.998	0.002
I49.8 Other specified cardiac arrhythmias	0.000	0.998	0.002
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.002
N76.3 Subacute and chronic vulvitis	0.000	0.998	0.002
I49 Other cardiac arrhythmias	0.000	0.998	0.002
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
L54 Erythema in diseases classified elsewhere	0.000	0.998	0.002
T18.1 Foreign body in oesophagus	0.002	0.998	0.000
N71.0 Acute inflammatory disease of uterus	0.000	0.998	0.002
O80.1 Spontaneous breech delivery	0.002	0.998	0.000
C01 Malignant neoplasm of base of tongue	0.002	0.998	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
C18.6 Descending colon	0.000	0.998	0.002
C18.9 Colon, unspecified	0.000	0.998	0.002
L51.1 Bullous erythema multiforme	0.000	0.998	0.002
N05.9 Unspecified	0.000	0.998	0.002
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
L50.6 Contact urticaria	0.000	0.998	0.002
L50.5 Cholinergic urticaria	0.000	0.998	0.002
L50.4 Vibratory urticaria	0.000	0.998	0.002
L50.3 Dermatographic urticaria	0.000	0.998	0.002
L50.2 Urticaria due to cold and heat	0.000	0.998	0.002
C84.5 Other and unspecified T-cell lymphomas	0.002	0.998	0.000
O82 Single delivery by Caesarean section	0.002	0.998	0.000
I49.1 Atrial premature depolarisation	0.000	0.998	0.002
N76.8 Other specified inflammation of vagina and vulva	0.000	0.998	0.002
O63.1 Prolonged second stage (of labour)	0.000	0.998	0.002
L51.8 Other erythema multiforme	0.000	0.998	0.002
L51.2 Toxic epidermal necrolysis [Lyell]	0.000	0.998	0.002
L51.0 Nonbullous erythema multiforme	0.000	0.998	0.002
M54.46 Lumbago with sciatica (Lumbar region)	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
F03 Unspecified dementia	0.002	0.998	0.000
D05.1 Intraductal carcinoma in situ	0.002	0.998	0.000
J39.2 Other diseases of pharynx	0.000	0.998	0.002
L50.8 Other urticaria	0.000	0.998	0.002
L51.9 Erythema multiforme, unspecified	0.000	0.998	0.002
S91.0 Open wound of ankle	0.002	0.998	0.000
O80-O84 Delivery	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.002
I49.3 Ventricular premature depolarisation	0.000	0.998	0.002
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.998	0.002
Z95.8 Presence of other cardiac and vascular implants and grafts	0.002	0.998	0.000
I49.2 Junctional premature depolarisation	0.000	0.998	0.002
L54.8 Erythema in other diseases classified elsewhere	0.000	0.998	0.002
L54.0 Erythema marginatum in acute rheumatic fever	0.000	0.998	0.002
S99.7 Multiple injuries of ankle and foot	0.002	0.998	0.000
O81 Single delivery by forceps and vacuum extractor	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
K86.3 Pseudocyst of pancreas	0.000	0.998	0.002
O81.0 Low forceps delivery	0.002	0.998	0.000
I49.0 Ventricular fibrillation and flutter	0.000	0.998	0.002
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
A49.0 Staphylococcal infection, unspecified	0.000	0.998	0.002
C81.9 Hodgkin's disease, unspecified	0.000	0.998	0.002
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.998	0.002
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.998	0.002
N04.9 Unspecified	0.000	0.998	0.002
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.002	0.998	0.000
O82.2 Delivery by Caesarean hysterectomy	0.002	0.998	0.000
R45.2 Unhappiness	0.002	0.998	0.000
S13.1 Dislocation of cervical vertebra	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.998	0.002
O80.8 Other single spontaneous delivery	0.001	0.998	0.000
U80.1 Methicillin resistant agent	0.002	0.998	0.000
C18.3 Hepatic flexure	0.000	0.998	0.002
J01.9 Acute sinusitis, unspecified	0.000	0.998	0.002
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.001	0.998	0.000
S97.0 Crushing injury of ankle	0.001	0.998	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.998	0.001
G93.9 Disorder of brain, unspecified	0.000	0.998	0.002
O81.4 Vacuum extractor delivery	0.002	0.998	0.000
O84 Multiple delivery	0.001	0.998	0.000
O83 Other assisted single delivery	0.001	0.998	0.000
H57.1 Ocular pain	0.002	0.998	0.000
S42.2 Fracture of upper end of humerus	0.000	0.998	0.002
S91 Open wound of ankle and foot	0.001	0.998	0.000
A49.9 Bacterial infection, unspecified	0.000	0.998	0.002
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.001
O81.5 Delivery by combination of forceps and vacuum extractor	0.001	0.998	0.000
O81.3 Other and unspecified forceps delivery	0.001	0.998	0.000
O81.2 Mid-cavity forceps with rotation	0.001	0.998	0.000
O81.1 Mid-cavity forceps delivery	0.001	0.998	0.000
S02.5 Fracture of tooth	0.002	0.998	0.000
D32.9 Meninges, unspecified	0.000	0.998	0.002
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.002	0.998	0.000
L52 Erythema nodosum	0.000	0.998	0.001
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.001	0.998	0.000
C04.9 Floor of mouth, unspecified	0.001	0.998	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.002	0.998	0.000
O82.0 Delivery by elective Caesarean section	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.001	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.001
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.998	0.001
Q18.0 Sinus, fistula and cyst of branchial cleft	0.001	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.001	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.001	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.001	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.001	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.001	0.998	0.000
S94.1 Injury of medial plantar nerve	0.001	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.001	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.001	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.001	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.001	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.001	0.998	0.000
S95.1 Injury of plantar artery of foot	0.001	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.001	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.998	0.000
S98.1 Traumatic amputation of one toe	0.001	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.001	0.998	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.999	0.001
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.000	0.999	0.001
E21.4 Other specified disorders of parathyroid gland	0.000	0.999	0.001
E21.2 Other hyperparathyroidism	0.000	0.999	0.001
F60 Specific personality disorders	0.001	0.999	0.000
Q12.0 Congenital cataract	0.001	0.999	0.000
T85.2 Mechanical complication of intraocular lens	0.000	0.999	0.001
W11.5 Trade and service area	0.001	0.999	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.999	0.001
I71.0 Dissection of aorta [any part]	0.000	0.999	0.001
I71 Aortic aneurysm and dissection	0.000	0.999	0.001
L92.0 Granuloma annulare	0.001	0.999	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.999	0.001
O83.9 Assisted single delivery, unspecified	0.001	0.999	0.000
O83.8 Other specified assisted single delivery	0.001	0.999	0.000
O83.4 Destructive operation for delivery	0.001	0.999	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.001	0.999	0.000
O83.2 Other manipulation-assisted delivery	0.001	0.999	0.000
O83.1 Other assisted breech delivery	0.001	0.999	0.000
O83.0 Breech extraction	0.001	0.999	0.000
O84.9 Multiple delivery, unspecified	0.001	0.999	0.000
O84.8 Other multiple delivery	0.001	0.999	0.000
O84.2 Multiple delivery, all by Caesarean section	0.001	0.999	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.001	0.999	0.000
O84.0 Multiple delivery, all spontaneous	0.001	0.999	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.001	0.999	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.000	0.999	0.001
S42.21 Fracture of upper end of humerus (open)	0.000	0.999	0.001
C10.9 Oropharynx, unspecified	0.001	0.999	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.999	0.001
S91.7 Multiple open wounds of ankle and foot	0.001	0.999	0.000
S91.2 Open wound of toe(s) with damage to nail	0.001	0.999	0.000
S02.51 Fracture of tooth (open)	0.001	0.999	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.001	0.999	0.000
S13.5 Sprain and strain of thyroid region	0.001	0.999	0.000
S13.3 Multiple dislocations of neck	0.001	0.999	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.001	0.999	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.001	0.999	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.999	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.001	0.999	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.001	0.999	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.001	0.999	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.001	0.999	0.000
S51.9 Open wound of forearm, part unspecified	0.000	0.999	0.001
R45 Symptoms and signs involving emotional state	0.001	0.999	0.000
S90 Superficial injury of ankle and foot	0.001	0.999	0.000
J39.9 Disease of upper respiratory tract, unspecified	0.000	0.999	0.001
L50.9 Urticaria, unspecified	0.000	0.999	0.001
O03.4 Incomplete, without complication	0.000	0.999	0.001
S93.4 Sprain and strain of ankle	0.001	0.999	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.999	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.999	0.000
C04 Malignant neoplasm of floor of mouth	0.001	0.999	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.999	0.001
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.001	0.999	0.000
E22.1 Hyperprolactinaemia	0.000	0.999	0.001
F60.8 Other specific personality disorders	0.001	0.999	0.000
F60.5 Anankastic personality disorder	0.001	0.999	0.000
F60.4 Histrionic personality disorder	0.001	0.999	0.000
F60.2 Dissocial personality disorder	0.001	0.999	0.000
F60.1 Schizoid personality disorder	0.001	0.999	0.000
F60.0 Paranoid personality disorder	0.001	0.999	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.001	0.999	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.999	0.001
E34.8 Other specified endocrine disorders	0.000	0.999	0.001
K12.3 Oral mucositis (ulcerative)	0.000	0.999	0.001
O82.9 Delivery by Caesarean section, unspecified	0.001	0.999	0.000
S71.1 Open wound of thigh	0.001	0.999	0.000
S90.0 Contusion of ankle	0.001	0.999	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.001	0.999	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.999	0.001
C04.0 Anterior floor of mouth	0.001	0.999	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.999	0.001
F60.6 Anxious [avoidant] personality disorder	0.001	0.999	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.999	0.001
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.999	0.001
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.999	0.001
R45.0 Nervousness	0.001	0.999	0.000
S05.1 Contusion of eyeball and orbital tissues	0.000	0.999	0.001
T31.0 Burns involving less than 10% of body surface	0.000	0.999	0.001
I62 Other nontraumatic intracranial haemorrhage	0.000	0.999	0.001
E22.0 Acromegaly and pituitary gigantism	0.000	0.999	0.001
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.001	0.999	0.000
E34.0 Carcinoid syndrome	0.000	0.999	0.001
R45.7 State of emotional shock and stress, unspecified	0.001	0.999	0.000
R45.3 Demoralisation and apathy	0.001	0.999	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.001	0.999	0.000
S90.2 Contusion of toe(s) with damage to nail	0.001	0.999	0.000
S90.1 Contusion of toe(s) without damage to nail	0.001	0.999	0.000
C10 Malignant neoplasm of oropharynx	0.001	0.999	0.000
J00 Acute nasopharyngitis [common cold]	0.000	0.999	0.001
M89.84 Other specified disorders of bone (Hand)	0.001	0.999	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.999	0.000
C04.8 Overlapping lesion of floor of mouth	0.001	0.999	0.000
C04.1 Lateral floor of mouth	0.001	0.999	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations