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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3217992
log Bayes Factor = 200.854
Chromosome 9   position 22,003,223  (GRCh37) Explore rs3217992 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
H40.9 Glaucoma, unspecified
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
1.000 0.000 0.000
I20.0 Unstable angina
1.000 0.000 0.000
I21.9 Acute myocardial infarction, unspecified
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
1.000 0.000 0.000
I25.2 Old myocardial infarction
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
1.000 0.000 0.000
Z95.5 Presence of coronary angioplasty implant and graft
1.000 0.000 0.000
Z95.1 Presence of aortocoronary bypass graft
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I21 Acute myocardial infarction
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I73.9 Peripheral vascular disease, unspecified
1.000 0.000 0.000
I22 Subsequent myocardial infarction
1.000 0.000 0.000
C71 Malignant neoplasm of brain
0.000 0.000 1.000
I73 Other peripheral vascular diseases
1.000 0.000 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
1.000 0.000 0.000
Chapter II Neoplasms
0.000 0.001 0.999
H40.1 Primary open-angle glaucoma
0.999 0.001 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.001 0.999
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.001 0.999
C44 Other malignant neoplasms of skin
0.000 0.001 0.999
H40 Glaucoma
0.999 0.001 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.999 0.001 0.000
E78.0 Pure hypercholesterolaemia
0.999 0.001 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.000 0.002 0.998
I21.4 Acute subendocardial myocardial infarction
0.998 0.002 0.000
D05 Carcinoma in situ of breast
0.000 0.002 0.998
I22.9 Subsequent myocardial infarction of unspecified site
0.998 0.002 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.997 0.003 0.000
I77 Other disorders of arteries and arterioles
0.997 0.003 0.000
D00-D09 In situ neoplasms
0.000 0.003 0.997
C71.9 Brain, unspecified
0.000 0.003 0.997
I21.0 Acute transmural myocardial infarction of anterior wall
0.997 0.003 0.000
I77.1 Stricture of artery
0.995 0.005 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.994 0.006 0.000
C44.5 Skin of trunk
0.000 0.007 0.993
I24 Other acute ischaemic heart diseases
0.991 0.009 0.000
C50-C50 Malignant neoplasm of breast
0.000 0.013 0.987
C44.0 Skin of lip
0.000 0.015 0.985
Chapter IX Diseases of the circulatory system
0.983 0.017 0.000
I74 Arterial embolism and thrombosis
0.981 0.019 0.000
I71 Aortic aneurysm and dissection
0.980 0.020 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.980 0.020 0.000
C50 Malignant neoplasm of breast
0.000 0.021 0.979
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.976 0.024 0.000
I24.8 Other forms of acute ischaemic heart disease
0.971 0.029 0.000
E11.9 Without complications
0.966 0.034 0.000
C71.2 Temporal lobe
0.000 0.036 0.964
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.048 0.952
I72 Other aneurysm
0.950 0.050 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.947 0.053 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.942 0.058 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.939 0.061 0.000
I20.8 Other forms of angina pectoris
0.936 0.064 0.000
I25.5 Ischaemic cardiomyopathy
0.935 0.065 0.000
C71.8 Overlapping lesion of brain
0.000 0.066 0.934
I22.1 Subsequent myocardial infarction of inferior wall
0.931 0.069 0.000
C71.1 Frontal lobe
0.000 0.069 0.931
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.071 0.929
C50.2 Upper-inner quadrant of breast
0.000 0.083 0.917
C15-C26 Malignant neoplasms of digestive organs
0.000 0.083 0.917
I70 Atherosclerosis
0.914 0.086 0.000
C50.5 Lower-outer quadrant of breast
0.000 0.088 0.912
C44.1 Skin of eyelid, including canthus
0.000 0.092 0.908
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.093 0.907
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.906 0.094 0.000
C02.9 Tongue, unspecified
0.000 0.096 0.904
C50.4 Upper-outer quadrant of breast
0.000 0.104 0.896
I25.3 Aneurysm of heart
0.892 0.107 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.892 0.108 0.000
C20 Malignant neoplasm of rectum
0.000 0.112 0.888
C21 Malignant neoplasm of anus and anal canal
0.000 0.117 0.883
D05.7 Other carcinoma in situ of breast
0.000 0.120 0.880
I70.2 Atherosclerosis of arteries of the extremities
0.879 0.121 0.000
Z95.3 Presence of xenogenic heart valve
0.876 0.124 0.000
E78.4 Other hyperlipidaemia
0.873 0.127 0.000
I72.3 Aneurysm of iliac artery
0.865 0.135 0.000
C50.9 Breast, unspecified
0.000 0.140 0.860
I25.4 Coronary artery aneurysm
0.856 0.144 0.000
C45 Mesothelioma
0.000 0.152 0.848
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.846 0.154 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.846 0.154 0.000
I50.1 Left ventricular failure
0.838 0.162 0.000
C44.2 Skin of ear and external auricular canal
0.000 0.169 0.831
I05-I09 Chronic rheumatic heart diseases
0.828 0.172 0.000
C71.0 Cerebrum, except lobes and ventricles
0.000 0.177 0.823
D05.1 Intraductal carcinoma in situ
0.000 0.178 0.822
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.817 0.183 0.000
C15 Malignant neoplasm of oesophagus
0.000 0.185 0.815
I50 Heart failure
0.814 0.186 0.000
I77.0 Arteriovenous fistula, acquired
0.813 0.187 0.000
I74.8 Embolism and thrombosis of other arteries
0.808 0.192 0.000
C45.7 Mesothelioma of other sites
0.000 0.194 0.806
I30-I52 Other forms of heart disease
0.803 0.197 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.796 0.204 0.000
C17 Malignant neoplasm of small intestine
0.000 0.205 0.795
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.000 0.210 0.790
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.215 0.785
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.217 0.783
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.221 0.779
I72.1 Aneurysm of artery of upper extremity
0.774 0.226 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.772 0.228 0.000
C21.1 Anal canal
0.000 0.229 0.771
I07 Rheumatic tricuspid valve diseases
0.771 0.229 0.000
C10 Malignant neoplasm of oropharynx
0.000 0.231 0.769
C44.6 Skin of upper limb, including shoulder
0.000 0.232 0.768
I25.0 Atherosclerotic cardiovascular disease, so described
0.767 0.233 0.000
C21.0 Anus, unspecified
0.000 0.233 0.767
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.238 0.762
H40.5 Glaucoma secondary to other eye disorders
0.762 0.238 0.000
I72.9 Aneurysm of unspecified site
0.761 0.239 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.761 0.239 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.757 0.243 0.000
C44.3 Skin of other and unspecified parts of face
0.000 0.252 0.748
I46 Cardiac arrest
0.747 0.253 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.000 0.254 0.746
C44.4 Skin of scalp and neck
0.000 0.255 0.745
I21.3 Acute transmural myocardial infarction of unspecified site
0.745 0.255 0.000
I51 Complications and ill-defined descriptions of heart disease
0.744 0.256 0.000
I07.1 Tricuspid insufficiency
0.731 0.269 0.000
C02.4 Lingual tonsil
0.000 0.270 0.730
I25.6 Silent myocardial ischaemia
0.729 0.271 0.000
C48.2 Peritoneum, unspecified
0.000 0.272 0.728
C71.3 Parietal lobe
0.000 0.272 0.728
C05 Malignant neoplasm of palate
0.000 0.275 0.725
C50.3 Lower-inner quadrant of breast
0.000 0.275 0.725
I46.0 Cardiac arrest with successful resuscitation
0.720 0.280 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.718 0.282 0.000
E78.2 Mixed hyperlipidaemia
0.717 0.283 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.717 0.283 0.000
C71.7 Brain stem
0.000 0.283 0.717
C71.6 Cerebellum
0.000 0.283 0.717
C71.5 Cerebral ventricle
0.000 0.283 0.717
C15.9 Oesophagus, unspecified
0.000 0.283 0.717
C44.8 Overlapping lesion of skin
0.000 0.284 0.716
H40.6 Glaucoma secondary to drugs
0.716 0.284 0.000
I77.5 Necrosis of artery
0.715 0.285 0.000
I77.4 Coeliac artery compression syndrome
0.715 0.285 0.000
I77.3 Arterial fibromuscular dysplasia
0.715 0.285 0.000
E78.8 Other disorders of lipoprotein metabolism
0.711 0.289 0.000
I72.0 Aneurysm of carotid artery
0.708 0.292 0.000
C02.1 Border of tongue
0.000 0.292 0.708
I51.7 Cardiomegaly
0.705 0.295 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.703 0.297 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.703 0.297 0.000
E78.3 Hyperchylomicronaemia
0.702 0.298 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.700 0.300 0.000
I22.8 Subsequent myocardial infarction of other sites
0.697 0.303 0.000
I70.1 Atherosclerosis of renal artery
0.696 0.303 0.000
I77.2 Rupture of artery
0.695 0.305 0.000
I72.8 Aneurysm of other specified arteries
0.694 0.306 0.000
C12 Malignant neoplasm of pyriform sinus
0.000 0.307 0.693
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.691 0.309 0.000
C23 Malignant neoplasm of gallbladder
0.000 0.312 0.688
I35 Nonrheumatic aortic valve disorders
0.687 0.313 0.000
Z95.2 Presence of prosthetic heart valve
0.685 0.315 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.681 0.319 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.681 0.319 0.000
I33 Acute and subacute endocarditis
0.681 0.319 0.000
D05.0 Lobular carcinoma in situ
0.000 0.321 0.679
C00 Malignant neoplasm of lip
0.000 0.321 0.678
C43 Malignant melanoma of skin
0.000 0.322 0.678
H40.4 Glaucoma secondary to eye inflammation
0.675 0.325 0.000
C07 Malignant neoplasm of parotid gland
0.000 0.326 0.674
I23 Certain current complications following acute myocardial infarction
0.673 0.327 0.000
I72.4 Aneurysm of artery of lower extremity
0.672 0.327 0.000
I72.2 Aneurysm of renal artery
0.670 0.330 0.000
C15.5 Lower third of oesophagus
0.000 0.331 0.669
I73.8 Other specified peripheral vascular diseases
0.668 0.332 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.666 0.334 0.000
C02.8 Overlapping lesion of tongue
0.000 0.334 0.666
C02.3 Anterior two-thirds of tongue, part unspecified
0.000 0.334 0.666
C02.0 Dorsal surface of tongue
0.000 0.334 0.666
H40.3 Glaucoma secondary to eye trauma
0.663 0.337 0.000
C17.0 Duodenum
0.000 0.337 0.663
H40.0 Glaucoma suspect
0.662 0.338 0.000
I51.6 Cardiovascular disease, unspecified
0.661 0.339 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.340 0.660
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.340 0.660
I00-I02 Acute rheumatic fever
0.659 0.341 0.000
C14.0 Pharynx, unspecified
0.000 0.345 0.655
C08.9 Major salivary gland, unspecified
0.000 0.348 0.652
C04 Malignant neoplasm of floor of mouth
0.000 0.349 0.651
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.000 0.349 0.651
C46 Kaposi's sarcoma
0.000 0.349 0.651
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.650 0.350 0.000
C02.2 Ventral surface of tongue
0.000 0.350 0.650
Z82.3 Family history of stroke
0.648 0.352 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.357 0.643
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.358 0.642
I09 Other rheumatic heart diseases
0.639 0.361 0.000
C11 Malignant neoplasm of nasopharynx
0.000 0.362 0.638
C10.9 Oropharynx, unspecified
0.000 0.363 0.637
C70 Malignant neoplasm of meninges
0.000 0.364 0.635
H40.8 Other glaucoma
0.634 0.365 0.000
C17.9 Small intestine, unspecified
0.000 0.366 0.634
D02.0 Larynx
0.000 0.367 0.633
C21.2 Cloacogenic zone
0.000 0.367 0.633
C06 Malignant neoplasm of other and unspecified parts of mouth
0.000 0.368 0.632
C50.8 Overlapping lesion of breast
0.000 0.369 0.631
I51.4 Myocarditis, unspecified
0.631 0.369 0.000
C50.6 Axillary tail of breast
0.000 0.369 0.631
I70.8 Atherosclerosis of other arteries
0.628 0.372 0.000
I50.9 Heart failure, unspecified
0.625 0.375 0.000
I74.5 Embolism and thrombosis of iliac artery
0.622 0.378 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.378 0.622
C45.9 Mesothelioma, unspecified
0.000 0.379 0.621
C09 Malignant neoplasm of tonsil
0.000 0.380 0.620
C71.4 Occipital lobe
0.000 0.381 0.619
I24.1 Dressler's syndrome
0.619 0.381 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.619 0.381 0.000
C50.0 Nipple and areola
0.000 0.382 0.618
C13 Malignant neoplasm of hypopharynx
0.000 0.382 0.617
D09 Carcinoma in situ of other and unspecified sites
0.000 0.383 0.617
I70.9 Generalised and unspecified atherosclerosis
0.615 0.385 0.000
C03 Malignant neoplasm of gum
0.000 0.385 0.615
I05 Rheumatic mitral valve diseases
0.614 0.386 0.000
C45.2 Mesothelioma of pericardium
0.000 0.392 0.608
C45.1 Mesothelioma of peritoneum
0.000 0.392 0.608
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.607 0.392 0.000
I79.1 Aortitis in diseases classified elsewhere
0.606 0.393 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.606 0.393 0.000
E78.6 Lipoprotein deficiency
0.606 0.394 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.598 0.401 0.000
C45.0 Mesothelioma of pleura
0.000 0.413 0.587
C17.1 Jejunum
0.000 0.415 0.585
C15.8 Overlapping lesion of oesophagus
0.000 0.416 0.584
C15.2 Abdominal part of oesophagus
0.000 0.416 0.584
C15.1 Thoracic part of oesophagus
0.000 0.416 0.584
C69 Malignant neoplasm of eye and adnexa
0.000 0.417 0.583
I43 Cardiomyopathy in diseases classified elsewhere
0.580 0.420 0.000
C05.9 Palate, unspecified
0.000 0.421 0.579
C15.4 Middle third of oesophagus
0.000 0.423 0.577
C08.0 Submandibular gland
0.000 0.423 0.577
I52 Other heart disorders in diseases classified elsewhere
0.576 0.424 0.000
I48 Atrial fibrillation and flutter
0.576 0.424 0.000
I41 Myocarditis in diseases classified elsewhere
0.576 0.424 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.576 0.424 0.000
I32 Pericarditis in diseases classified elsewhere
0.576 0.424 0.000
I33.9 Acute endocarditis, unspecified
0.574 0.426 0.000
Z95.0 Presence of cardiac pacemaker
0.573 0.427 0.000
D04 Carcinoma in situ of skin
0.000 0.429 0.571
C15.3 Upper third of oesophagus
0.000 0.430 0.570
C17.8 Overlapping lesion of small intestine
0.000 0.430 0.570
C17.3 Meckel's diverticulum
0.000 0.430 0.570
C17.2 Ileum
0.000 0.431 0.569
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.433 0.567
C48.8 Overlapping lesion of retroperitoneum and peritoneum
0.000 0.434 0.566
I51.5 Myocardial degeneration
0.566 0.434 0.000
C15.0 Cervical part of oesophagus
0.000 0.434 0.566
C32 Malignant neoplasm of larynx
0.000 0.435 0.565
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.435 0.565
C72.0 Spinal cord
0.000 0.435 0.565
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.435 0.564
D06 Carcinoma in situ of cervix uteri
0.000 0.436 0.564
D02.4 Respiratory system, unspecified
0.000 0.437 0.563
D02.3 Other parts of respiratory system
0.000 0.437 0.563
D02.2 Bronchus and lung
0.000 0.437 0.563
D02.1 Trachea
0.000 0.437 0.563
C48.0 Retroperitoneum
0.000 0.438 0.562
C08.8 Overlapping lesion of major salivary glands
0.000 0.439 0.561
C08.1 Sublingual gland
0.000 0.439 0.561
I37 Pulmonary valve disorders
0.560 0.440 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.559 0.441 0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx
0.000 0.441 0.559
C14.2 Waldeyer's ring
0.000 0.441 0.559
C43.4 Malignant melanoma of scalp and neck
0.000 0.446 0.554
I06 Rheumatic aortic valve diseases
0.553 0.447 0.000
I07.9 Tricuspid valve disease, unspecified
0.553 0.447 0.000
I07.8 Other tricuspid valve diseases
0.553 0.447 0.000
I07.2 Tricuspid stenosis with insufficiency
0.553 0.447 0.000
I07.0 Tricuspid stenosis
0.553 0.447 0.000
E78.1 Pure hyperglyceridaemia
0.552 0.448 0.000
C10.8 Overlapping lesion of oropharynx
0.000 0.449 0.551
C10.4 Branchial cleft
0.000 0.449 0.551
C10.3 Posterior wall of oropharynx
0.000 0.449 0.551
C10.2 Lateral wall of oropharynx
0.000 0.449 0.551
C10.1 Anterior surface of epiglottis
0.000 0.449 0.551
C10.0 Vallecula
0.000 0.449 0.551
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.449 0.551
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.549 0.450 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.456 0.544
I70.10 Atherosclerosis of renal artery (without gangrene)
0.541 0.459 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.538 0.462 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.537 0.463 0.000
I46.1 Sudden cardiac death, so described
0.536 0.464 0.000
C72.9 Central nervous system, unspecified
0.000 0.465 0.535
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.000 0.465 0.535
C72.5 Other and unspecified cranial nerves
0.000 0.465 0.535
C72.4 Acoustic nerve
0.000 0.465 0.535
C72.3 Optic nerve
0.000 0.465 0.535
C72.2 Olfactory nerve
0.000 0.465 0.535
C72.1 Cauda equina
0.000 0.465 0.535
I51.2 Rupture of papillary muscle, not elsewhere classified
0.534 0.466 0.000
I40 Acute myocarditis
0.531 0.469 0.000
C16 Malignant neoplasm of stomach
0.000 0.471 0.529
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.529 0.471 0.000
I05.0 Mitral stenosis
0.528 0.472 0.000
I35.1 Aortic (valve) insufficiency
0.527 0.473 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.473 0.527
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.475 0.525
I33.0 Acute and subacute infective endocarditis
0.524 0.476 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.479 0.521
C05.8 Overlapping lesion of palate
0.000 0.480 0.520
C05.2 Uvula
0.000 0.480 0.520
C05.0 Hard palate
0.000 0.480 0.520
I51.0 Cardiac septal defect, acquired
0.511 0.489 0.000
H40.2 Primary angle-closure glaucoma
0.506 0.494 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.505 0.495 0.000
I09.9 Rheumatic heart disease, unspecified
0.503 0.496 0.000
C50.1 Central portion of breast
0.000 0.497 0.503
I36 Nonrheumatic tricuspid valve disorders
0.502 0.498 0.000
H40-H42 Glaucoma
0.502 0.498 0.000
C32.0 Glottis
0.000 0.500 0.500
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.500 0.499
I70.11 Atherosclerosis of renal artery (with gangrene)
0.499 0.500 0.000
C05.1 Soft palate
0.000 0.504 0.496
C00.0 External upper lip
0.000 0.505 0.495
E11 Non-insulin-dependent diabetes mellitus
0.493 0.507 0.000
C04.9 Floor of mouth, unspecified
0.000 0.508 0.492
C30 Malignant neoplasm of nasal cavity and middle ear
0.000 0.508 0.492
D01.2 Rectum
0.000 0.509 0.491
C48.1 Specified parts of peritoneum
0.000 0.512 0.488
I70.0 Atherosclerosis of aorta
0.488 0.512 0.000
C00.8 Overlapping lesion of lip
0.000 0.513 0.486
C00.6 Commissure of lip
0.000 0.513 0.486
C00.5 Lip, unspecified, inner aspect
0.000 0.513 0.486
C00.4 Lower lip, inner aspect
0.000 0.513 0.486
C00.3 Upper lip, inner aspect
0.000 0.513 0.486
C00.2 External lip, unspecified
0.000 0.513 0.486
C00.1 External lower lip
0.000 0.513 0.486
C43.8 Overlapping malignant melanoma of skin
0.000 0.514 0.486
C43.0 Malignant melanoma of lip
0.000 0.514 0.486
D04.6 Skin of upper limb, including shoulder
0.000 0.515 0.485
C31 Malignant neoplasm of accessory sinuses
0.000 0.517 0.483
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.483 0.517 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.483 0.517 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.483 0.517 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.483 0.517 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.483 0.517 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.483 0.517 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.483 0.517 0.000
D04.3 Skin of other and unspecified parts of face
0.000 0.518 0.482
C06.2 Retromolar area
0.000 0.521 0.479
D09.1 Other and unspecified urinary organs
0.000 0.523 0.477
I05.1 Rheumatic mitral insufficiency
0.477 0.523 0.000
I35.8 Other aortic valve disorders
0.475 0.525 0.000
D01.9 Digestive organ, unspecified
0.000 0.526 0.473
D01.7 Other specified digestive organs
0.000 0.526 0.473
D01.5 Liver, gallbladder and bile ducts
0.000 0.526 0.473
D01.4 Other and unspecified parts of intestine
0.000 0.526 0.473
D01.1 Rectosigmoid junction
0.000 0.526 0.473
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.000 0.527 0.473
C00.9 Lip, unspecified
0.000 0.527 0.473
I02 Rheumatic chorea
0.472 0.527 0.000
I01 Rheumatic fever with heart involvement
0.472 0.527 0.000
C69.9 Eye, unspecified
0.000 0.530 0.470
D04.2 Skin of ear and external auricular canal
0.000 0.530 0.470
D01.0 Colon
0.000 0.530 0.469
D06.0 Endocervix
0.000 0.531 0.469
C04.8 Overlapping lesion of floor of mouth
0.000 0.533 0.467
C04.1 Lateral floor of mouth
0.000 0.533 0.467
C46.9 Kaposi's sarcoma, unspecified
0.000 0.533 0.466
C46.8 Kaposi's sarcoma of multiple organs
0.000 0.533 0.466
C46.7 Kaposi's sarcoma of other sites
0.000 0.533 0.466
C46.3 Kaposi's sarcoma of lymph nodes
0.000 0.533 0.466
C46.2 Kaposi's sarcoma of palate
0.000 0.533 0.466
C46.1 Kaposi's sarcoma of soft tissue
0.000 0.533 0.466
C46.0 Kaposi's sarcoma of skin
0.000 0.533 0.466
C47.9 Peripheral nerves and autonomic nervous system, unspecified
0.000 0.533 0.466
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system
0.000 0.533 0.466
C47.6 Peripheral nerves of trunk, unspecified
0.000 0.533 0.466
C47.5 Peripheral nerves of pelvis
0.000 0.533 0.466
C47.4 Peripheral nerves of abdomen
0.000 0.533 0.466
C47.3 Peripheral nerves of thorax
0.000 0.533 0.466
C47.2 Peripheral nerves of lower limb, including hip
0.000 0.533 0.466
C47.1 Peripheral nerves of upper limb, including shoulder
0.000 0.533 0.466
C47.0 Peripheral nerves of head, face and neck
0.000 0.533 0.466
C37 Malignant neoplasm of thymus
0.000 0.536 0.464
E78.5 Hyperlipidaemia, unspecified
0.463 0.537 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.000 0.539 0.461
D00.2 Stomach
0.000 0.539 0.460
I09.8 Other specified rheumatic heart diseases
0.458 0.542 0.000
I09.2 Chronic rheumatic pericarditis
0.458 0.542 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.458 0.542 0.000
I09.0 Rheumatic myocarditis
0.458 0.542 0.000
C11.8 Overlapping lesion of nasopharynx
0.000 0.543 0.457
C11.3 Anterior wall of nasopharynx
0.000 0.543 0.457
C11.2 Lateral wall of nasopharynx
0.000 0.543 0.457
C11.1 Posterior wall of nasopharynx
0.000 0.543 0.457
C11.0 Superior wall of nasopharynx
0.000 0.543 0.457
C70.9 Meninges, unspecified
0.000 0.544 0.456
C70.1 Spinal meninges
0.000 0.544 0.456
C38 Malignant neoplasm of heart, mediastinum and pleura
0.000 0.545 0.455
C24.9 Biliary tract, unspecified
0.000 0.545 0.455
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.000 0.547 0.453
C06.1 Vestibule of mouth
0.000 0.547 0.453
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.452 0.548 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.450 0.549 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.000 0.551 0.449
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.446 0.554 0.000
C24.8 Overlapping lesion of biliary tract
0.000 0.554 0.446
Z82.2 Family history of deafness and hearing loss
0.445 0.554 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.000 0.555 0.445
C09.8 Overlapping lesion of tonsil
0.000 0.555 0.444
C09.0 Tonsillar fossa
0.000 0.555 0.444
D00.0 Lip, oral cavity and pharynx
0.000 0.557 0.443
C13.8 Overlapping lesion of hypopharynx
0.000 0.557 0.443
C13.2 Posterior wall of hypopharynx
0.000 0.557 0.443
C13.1 Aryepiglottic fold, hypopharyngeal aspect
0.000 0.557 0.443
D09.9 Carcinoma in situ, unspecified
0.000 0.557 0.443
D09.7 Carcinoma in situ of other specified sites
0.000 0.557 0.443
D09.3 Thyroid and other endocrine glands
0.000 0.557 0.443
D09.2 Eye
0.000 0.557 0.443
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.442 0.557 0.000
D04.9 Skin, unspecified
0.000 0.558 0.442
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.441 0.559 0.000
C03.9 Gum, unspecified
0.000 0.559 0.441
C03.0 Upper gum
0.000 0.559 0.441
C32.9 Larynx, unspecified
0.000 0.560 0.440
I05.8 Other mitral valve diseases
0.440 0.560 0.000
I23.8 Other current complications following acute myocardial infarction
0.439 0.561 0.000
I46.9 Cardiac arrest, unspecified
0.438 0.562 0.000
C24.0 Extrahepatic bile duct
0.000 0.562 0.438
C06.0 Cheek mucosa
0.000 0.562 0.437
E11.1 With ketoacidosis
0.432 0.568 0.000
D03 Melanoma in situ
0.000 0.569 0.431
C13.0 Postcricoid region
0.000 0.570 0.430
C16.1 Fundus of stomach
0.000 0.570 0.430
I00 Rheumatic fever without mention of heart involvement
0.426 0.573 0.000
I05.2 Mitral stenosis with insufficiency
0.424 0.576 0.000
C09.1 Tonsillar pillar (anterior) (posterior)
0.000 0.576 0.424
I70.80 Atherosclerosis of other arteries (without gangrene)
0.423 0.576 0.000
C16.5 Lesser curvature of stomach, unspecified
0.000 0.578 0.422
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.421 0.579 0.000
E11.5 With peripheral circulatory complications
0.421 0.579 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.420 0.580 0.000
C69.8 Overlapping lesion of eye and adnexa
0.000 0.582 0.418
C69.6 Orbit
0.000 0.582 0.418
C69.5 Lachrymal gland and duct
0.000 0.582 0.418
C69.4 Ciliary body
0.000 0.582 0.418
C69.2 Retina
0.000 0.582 0.418
C69.1 Cornea
0.000 0.582 0.418
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.416 0.584 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.416 0.584 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.416 0.584 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.413 0.587 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.413 0.587 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.413 0.587 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.413 0.587 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.413 0.587 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.413 0.587 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.413 0.587 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.413 0.587 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.413 0.587 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.413 0.587 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.413 0.587 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.413 0.587 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.413 0.587 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.413 0.587 0.000
I48.4 Atypical atrial flutter
0.413 0.587 0.000
I48.3 Typical atrial flutter
0.413 0.587 0.000
I48.2 Chronic atrial fibrillation
0.413 0.587 0.000
I48.1 Persistent atrial fibrillation
0.413 0.587 0.000
I48.0 Paroxysmal atrial fibrillation
0.413 0.587 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.413 0.587 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.413 0.587 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.413 0.587 0.000
C11.9 Nasopharynx, unspecified
0.000 0.588 0.412
D00.1 Oesophagus
0.000 0.590 0.410
D04.8 Skin of other sites
0.000 0.590 0.410
D04.0 Skin of lip
0.000 0.590 0.410
C24.1 Ampulla of Vater
0.000 0.592 0.407
C09.9 Tonsil, unspecified
0.000 0.594 0.406
C32.8 Overlapping lesion of larynx
0.000 0.594 0.405
C32.3 Laryngeal cartilage
0.000 0.594 0.405
C32.2 Subglottis
0.000 0.594 0.405
D06.7 Other parts of cervix
0.000 0.596 0.404
C16.6 Greater curvature of stomach, unspecified
0.000 0.597 0.403
I37.9 Pulmonary valve disorder, unspecified
0.401 0.599 0.000
I37.8 Other pulmonary valve disorders
0.401 0.599 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.401 0.599 0.000
C04.0 Anterior floor of mouth
0.000 0.599 0.401
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.401 0.599 0.000
D01.3 Anus and anal canal
0.000 0.600 0.400
I37.0 Pulmonary valve stenosis
0.398 0.601 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.397 0.603 0.000
I06.8 Other rheumatic aortic valve diseases
0.397 0.603 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.397 0.603 0.000
C33 Malignant neoplasm of trachea
0.000 0.605 0.395
C01 Malignant neoplasm of base of tongue
0.000 0.605 0.394
I06.1 Rheumatic aortic insufficiency
0.394 0.606 0.000
C13.9 Hypopharynx, unspecified
0.000 0.606 0.393
I51.8 Other ill-defined heart diseases
0.393 0.607 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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