TreeWAS – Variant ID: rs12714145

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I20.9 Angina pectoris, unspecified	1.000	0.000	0.000
I20 Angina pectoris	1.000	0.000	0.000
I21 Acute myocardial infarction	1.000	0.000	0.000
I21.9 Acute myocardial infarction, unspecified	0.999	0.001	0.000
C61 Malignant neoplasm of prostate	0.000	0.005	0.995
I21.0 Acute transmural myocardial infarction of anterior wall	0.995	0.005	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.989	0.011	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.973	0.027	0.000
I25.3 Aneurysm of heart	0.904	0.096	0.000
I24 Other acute ischaemic heart diseases	0.864	0.136	0.000
I25.5 Ischaemic cardiomyopathy	0.811	0.189	0.000
I20.8 Other forms of angina pectoris	0.810	0.190	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.809	0.191	0.000
I25.4 Coronary artery aneurysm	0.760	0.240	0.000
I25.6 Silent myocardial ischaemia	0.757	0.242	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283	0.000
I23 Certain current complications following acute myocardial infarction	0.700	0.300	0.000
I25.2 Old myocardial infarction	0.689	0.311	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.688	0.311	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.687	0.312	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.652	0.348	0.000
I20.0 Unstable angina	0.635	0.365	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.615	0.385	0.000
I20.1 Angina pectoris with documented spasm	0.589	0.411	0.000
I24.1 Dressler's syndrome	0.584	0.416	0.000
I22 Subsequent myocardial infarction	0.507	0.493	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.502	0.498	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.8 Other current complications following acute myocardial infarction	0.485	0.515	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.448	0.552	0.000
I24.8 Other forms of acute ischaemic heart disease	0.429	0.571	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.391	0.609	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.354	0.646	0.000
C60-C63 Malignant neoplasms of male genital organs	0.000	0.671	0.329
Z95 Presence of cardiac and vascular implants and grafts	0.319	0.681	0.000
Z95.1 Presence of aortocoronary bypass graft	0.308	0.692	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.294	0.706	0.000
Z95.2 Presence of prosthetic heart valve	0.285	0.715	0.000
Z95.3 Presence of xenogenic heart valve	0.245	0.755	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.240	0.760	0.000
I22.8 Subsequent myocardial infarction of other sites	0.232	0.768	0.000
Z95.4 Presence of other heart-valve replacement	0.229	0.771	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.000	0.771	0.229
C60 Malignant neoplasm of penis	0.000	0.779	0.221
C62 Malignant neoplasm of testis	0.000	0.780	0.220
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.209	0.791	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.206	0.794	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.185	0.815	0.000
D17 Benign lipomatous neoplasm	0.180	0.820	0.000
C62.1 Descended testis	0.000	0.826	0.174
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.168	0.832	0.000
C63.9 Male genital organ, unspecified	0.000	0.836	0.164
C63.8 Overlapping lesion of male genital organs	0.000	0.836	0.164
C63.7 Other specified male genital organs	0.000	0.836	0.164
C63.1 Spermatic cord	0.000	0.836	0.164
C63.0 Epididymis	0.000	0.836	0.164
C60.9 Penis, unspecified	0.000	0.838	0.162
I21.4 Acute subendocardial myocardial infarction	0.159	0.841	0.000
C60.8 Overlapping lesion of penis	0.000	0.841	0.159
C60.2 Body of penis	0.000	0.841	0.159
C62.0 Undescended testis	0.000	0.842	0.158
C63.2 Scrotum	0.000	0.843	0.157
C60.0 Prepuce	0.000	0.844	0.156
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.144	0.856	0.000
C60.1 Glans penis	0.000	0.856	0.143
Z95.8 Presence of other cardiac and vascular implants and grafts	0.135	0.865	0.000
C62.9 Testis, unspecified	0.000	0.883	0.117
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.116	0.884	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.101	0.899	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.080	0.920	0.000
Z95.0 Presence of cardiac pacemaker	0.064	0.936	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.059	0.941	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.056	0.944	0.000
I51.7 Cardiomegaly	0.051	0.949	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.979	0.021
M89.8 Other specified disorders of bone	0.018	0.982	0.000
M89 Other disorders of bone	0.017	0.983	0.000
M89.0 Algoneurodystrophy	0.017	0.983	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.016	0.984	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.016	0.984	0.000
M89.04 Algoneurodystrophy (Hand)	0.015	0.985	0.000
M89.9 Disorder of bone, unspecified	0.015	0.985	0.000
M89.3 Hypertrophy of bone	0.015	0.985	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.015	0.985	0.000
M89.84 Other specified disorders of bone (Hand)	0.015	0.985	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.014	0.986	0.000
M89.88 Other specified disorders of bone (Other)	0.014	0.986	0.000
M89.83 Other specified disorders of bone (Forearm)	0.014	0.986	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.014	0.986	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.014	0.986	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.013	0.987	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.013	0.987	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.013	0.987	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.012	0.987	0.000
M89.6 Osteopathy after poliomyelitis	0.012	0.988	0.000
M89.2 Other disorders of bone development and growth	0.012	0.988	0.000
M89.1 Epiphyseal arrest	0.012	0.988	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.000	0.988	0.012
M89.08 Algoneurodystrophy (Other)	0.012	0.988	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.012	0.988	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.012	0.988	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.012	0.988	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.012	0.988	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.012	0.988	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.988	0.012
M89.03 Algoneurodystrophy (Forearm)	0.012	0.988	0.000
M89.5 Osteolysis	0.012	0.988	0.000
U89.8 Agent resistant to other single specified antibiotic	0.012	0.988	0.000
M89.38 Hypertrophy of bone (Other)	0.011	0.989	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.011	0.989	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.011	0.989	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.011	0.989	0.000
M89.98 Disorder of bone, unspecified (Other)	0.011	0.989	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.011	0.989	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.011	0.989	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.011	0.989	0.000
M89.34 Hypertrophy of bone (Hand)	0.011	0.989	0.000
M89.33 Hypertrophy of bone (Forearm)	0.011	0.989	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.011	0.989	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.011	0.989	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.011	0.989	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.011	0.989	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.011	0.989	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.011	0.989	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.011	0.989	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.010	0.989	0.000
R45.1 Restlessness and agitation	0.000	0.989	0.011
M89.19 Epiphyseal arrest (Site unspecified)	0.009	0.991	0.000
M89.18 Epiphyseal arrest (Other)	0.009	0.991	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.009	0.991	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.009	0.991	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.009	0.991	0.000
M89.14 Epiphyseal arrest (Hand)	0.009	0.991	0.000
M89.13 Epiphyseal arrest (Forearm)	0.009	0.991	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.009	0.991	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.009	0.991	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.009	0.991	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.009	0.991	0.000
M89.28 Other disorders of bone development and growth (Other)	0.009	0.991	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.009	0.991	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.009	0.991	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.009	0.991	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.009	0.991	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.009	0.991	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.009	0.991	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.009	0.991	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.009	0.991	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.009	0.991	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.009	0.991	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.009	0.991	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.009	0.991	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.009	0.991	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.009	0.991	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.009	0.991	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.009	0.991	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.009	0.991	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.009	0.991	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.009	0.991	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.009	0.991	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.009	0.991	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.009	0.991	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.009	0.991	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.009	0.991	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.009	0.991	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.009	0.991	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.009	0.991	0.000
M89.59 Osteolysis (Site unspecified)	0.009	0.991	0.000
M89.58 Osteolysis (Other)	0.009	0.991	0.000
M89.57 Osteolysis (Ankle and foot)	0.009	0.991	0.000
M89.56 Osteolysis (Lower leg)	0.009	0.991	0.000
M89.54 Osteolysis (Hand)	0.009	0.991	0.000
M89.53 Osteolysis (Forearm)	0.009	0.991	0.000
M89.52 Osteolysis (Upper arm)	0.009	0.991	0.000
M89.51 Osteolysis (Shoulder region)	0.009	0.991	0.000
M89.50 Osteolysis (Multiple sites)	0.009	0.991	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.009	0.991	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.991	0.009
M89.55 Osteolysis (Pelvic region and thigh)	0.008	0.991	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.008	0.991	0.000
H66.9 Otitis media, unspecified	0.008	0.992	0.000
R45.2 Unhappiness	0.000	0.992	0.008
H66 Suppurative and unspecified otitis media	0.008	0.992	0.000
R45 Symptoms and signs involving emotional state	0.000	0.992	0.008
H66.3 Other chronic suppurative otitis media	0.007	0.993	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.007	0.993	0.000
H65-H75 Diseases of middle ear and mastoid	0.007	0.993	0.000
H74 Other disorders of middle ear and mastoid	0.007	0.993	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.007	0.993	0.000
H74.0 Tympanosclerosis	0.007	0.993	0.000
B02.9 Zoster without complication	0.000	0.993	0.007
H71 Cholesteatoma of middle ear	0.007	0.993	0.000
R45.4 Irritability and anger	0.000	0.993	0.007
E27.1 Primary adrenocortical insufficiency	0.000	0.993	0.007
H74.2 Discontinuity and dislocation of ear ossicles	0.006	0.993	0.000
H65 Nonsuppurative otitis media	0.007	0.993	0.000
R45.7 State of emotional shock and stress, unspecified	0.000	0.994	0.006
H65.9 Nonsuppurative otitis media, unspecified	0.006	0.994	0.000
H73 Other disorders of tympanic membrane	0.006	0.994	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.006	0.994	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.006	0.994	0.000
H68 Eustachian salpingitis and obstruction	0.006	0.994	0.000
R45.3 Demoralisation and apathy	0.000	0.994	0.006
G81.9 Hemiplegia, unspecified	0.000	0.994	0.006
R16.1 Splenomegaly, not elsewhere classified	0.000	0.994	0.006
U89 Agent resistant to other and unspecified antibiotics	0.006	0.994	0.000
R45.0 Nervousness	0.000	0.994	0.006
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.005	0.995	0.000
H67 Otitis media in diseases classified elsewhere	0.005	0.995	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.005	0.995	0.000
J93.9 Pneumothorax, unspecified	0.005	0.995	0.000
R45.6 Physical violence	0.000	0.995	0.005
H73.8 Other specified disorders of tympanic membrane	0.005	0.995	0.000
H65.4 Other chronic nonsuppurative otitis media	0.005	0.995	0.000
H66.4 Suppurative otitis media, unspecified	0.005	0.995	0.000
H66.0 Acute suppurative otitis media	0.005	0.995	0.000
Q23.1 Congenital insufficiency of aortic valve	0.005	0.995	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.005	0.995	0.000
H74.1 Adhesive middle ear disease	0.005	0.995	0.000
R45.8 Other symptoms and signs involving emotional state	0.000	0.995	0.005
H72 Perforation of tympanic membrane	0.005	0.995	0.000
H73.1 Chronic myringitis	0.005	0.995	0.000
H65.2 Chronic serous otitis media	0.005	0.995	0.000
I51 Complications and ill-defined descriptions of heart disease	0.005	0.995	0.000
H68.1 Obstruction of Eustachian tube	0.005	0.995	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.005	0.995	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.005	0.995	0.000
H73.0 Acute myringitis	0.005	0.995	0.000
H65.1 Other acute nonsuppurative otitis media	0.005	0.995	0.000
H72.1 Attic perforation of tympanic membrane	0.005	0.995	0.000
H65.0 Acute serous otitis media	0.005	0.995	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.005	0.995	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.005	0.995	0.000
E27 Other disorders of adrenal gland	0.000	0.995	0.005
H68.0 Eustachian salpingitis	0.004	0.995	0.000
R45.5 Hostility	0.000	0.995	0.004
E21.0 Primary hyperparathyroidism	0.000	0.996	0.004
E27.2 Addisonian crisis	0.000	0.996	0.004
O42 Premature rupture of membranes	0.000	0.996	0.004
H74.4 Polyp of middle ear	0.004	0.996	0.000
H69 Other disorders of Eustachian tube	0.004	0.996	0.000
H72.2 Other marginal perforations of tympanic membrane	0.004	0.996	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.004	0.996	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.004	0.996	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.004	0.996	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.004	0.996	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
G37 Other demyelinating diseases of central nervous system	0.004	0.996	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.996	0.004
E07.9 Disorder of thyroid, unspecified	0.004	0.996	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.004	0.996	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.996	0.004
H65.3 Chronic mucoid otitis media	0.004	0.996	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.996	0.004
I51.3 Intracardiac thrombosis, not elsewhere classified	0.004	0.996	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.004	0.996	0.000
U89.9 Agent resistant to unspecified antibiotic	0.004	0.996	0.000
I51.6 Cardiovascular disease, unspecified	0.004	0.996	0.000
H70 Mastoiditis and related conditions	0.004	0.996	0.000
O02.1 Missed abortion	0.000	0.996	0.004
I51.5 Myocardial degeneration	0.004	0.996	0.000
H72.0 Central perforation of tympanic membrane	0.004	0.996	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.004	0.996	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.996	0.003
E27.0 Other adrenocortical overactivity	0.000	0.996	0.003
I51.4 Myocarditis, unspecified	0.003	0.996	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.997	0.003
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.997	0.003
M25.86 Other specified joint disorders (Lower leg)	0.003	0.997	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.997	0.003
H69.0 Patulous Eustachian tube	0.003	0.997	0.000
Q23 Congenital malformations of aortic and mitral valves	0.003	0.997	0.000
G37.5 Concentric sclerosis [Balo]	0.003	0.997	0.000
G37.4 Subacute necrotising myelitis	0.003	0.997	0.000
G37.2 Central pontine myelinolysis	0.003	0.997	0.000
G37.1 Central demyelination of corpus callosum	0.003	0.997	0.000
G37.0 Diffuse sclerosis	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.997	0.003
H72.9 Perforation of tympanic membrane, unspecified	0.003	0.997	0.000
G81 Hemiplegia	0.000	0.997	0.003
I51.0 Cardiac septal defect, acquired	0.003	0.997	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.003	0.997	0.000
Z80.0 Family history of malignant neoplasm of digestive organs	0.003	0.997	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.997	0.003
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.997	0.003
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.997	0.003
H69.9 Eustachian tube disorder, unspecified	0.003	0.997	0.000
H70.2 Petrositis	0.003	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.997	0.003
T92 Sequelae of injuries of upper limb	0.000	0.997	0.003
E22.0 Acromegaly and pituitary gigantism	0.000	0.997	0.003
S01.1 Open wound of eyelid and periocular area	0.003	0.997	0.000
H70.1 Chronic mastoiditis	0.003	0.997	0.000
H70.0 Acute mastoiditis	0.003	0.997	0.000
I51.9 Heart disease, unspecified	0.003	0.997	0.000
T92.0 Sequelae of open wound of upper limb	0.000	0.997	0.003
E22 Hyperfunction of pituitary gland	0.000	0.997	0.003
D86.8 Sarcoidosis of other and combined sites	0.000	0.997	0.003
E21.4 Other specified disorders of parathyroid gland	0.000	0.997	0.003
G37.8 Other specified demyelinating diseases of central nervous system	0.003	0.997	0.000
Q23.0 Congenital stenosis of aortic valve	0.003	0.997	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.997	0.003
H70.8 Other mastoiditis and related conditions	0.002	0.997	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.003	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
S01.9 Open wound of head, part unspecified	0.000	0.997	0.003
M25.83 Other specified joint disorders (Forearm)	0.003	0.997	0.000
H72.8 Other perforations of tympanic membrane	0.002	0.997	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.997	0.003
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.003	0.997	0.000
G81.1 Spastic hemiplegia	0.000	0.997	0.002
G81.0 Flaccid hemiplegia	0.000	0.997	0.002
H69.8 Other specified disorders of Eustachian tube	0.002	0.997	0.000
E21.2 Other hyperparathyroidism	0.000	0.997	0.002
M25.8 Other specified joint disorders	0.003	0.997	0.000
E34 Other endocrine disorders	0.000	0.997	0.003
T92.4 Sequelae of injury of nerve of upper limb	0.000	0.997	0.002
E29 Testicular dysfunction	0.000	0.997	0.002
A87.9 Viral meningitis, unspecified	0.003	0.997	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.003	0.997	0.000
F43.2 Adjustment disorders	0.003	0.997	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.997	0.003
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.000	0.997	0.002
J10 Influenza due to identified influenza virus	0.002	0.997	0.000
H70.9 Mastoiditis, unspecified	0.002	0.998	0.000
D23.5 Skin of trunk	0.000	0.998	0.002
H36.0 Diabetic retinopathy	0.000	0.998	0.002
H90.5 Sensorineural hearing loss, unspecified	0.000	0.998	0.002
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.002	0.998	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.998	0.002
T92.1 Sequelae of fracture of arm	0.000	0.998	0.002
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E32 Diseases of thymus	0.000	0.998	0.002
E30 Disorders of puberty, not elsewhere classified	0.000	0.998	0.002
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.002
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.998	0.002
J38.4 Oedema of larynx	0.000	0.998	0.002
G35 Multiple sclerosis	0.002	0.998	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.998	0.002
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.998	0.002
E22.8 Other hyperfunction of pituitary gland	0.000	0.998	0.002
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.000	0.998	0.002
E31 Polyglandular dysfunction	0.000	0.998	0.002
E26 Hyperaldosteronism	0.000	0.998	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.998	0.002
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.998	0.002
E27.8 Other specified disorders of adrenal gland	0.000	0.998	0.002
E29.1 Testicular hypofunction	0.000	0.998	0.002
M25.82 Other specified joint disorders (Upper arm)	0.002	0.998	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.002	0.998	0.000
D86 Sarcoidosis	0.000	0.998	0.002
F29 Unspecified nonorganic psychosis	0.002	0.998	0.000
G36 Other acute disseminated demyelination	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.002
K75.0 Abscess of liver	0.000	0.998	0.002
Z80.8 Family history of malignant neoplasm of other organs or systems	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.998	0.002
Z54.0 Convalescence following surgery	0.000	0.998	0.002
E20 Hypoparathyroidism	0.000	0.998	0.002
M25.89 Other specified joint disorders (Site unspecified)	0.002	0.998	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.000	0.998	0.002
E34.4 Constitutional tall stature	0.000	0.998	0.002
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.998	0.002
E34.1 Other hypersecretion of intestinal hormones	0.000	0.998	0.002
M25.88 Other specified joint disorders (Other)	0.002	0.998	0.000
E25 Adrenogenital disorders	0.000	0.998	0.002
E29.9 Testicular dysfunction, unspecified	0.000	0.998	0.002
E29.8 Other testicular dysfunction	0.000	0.998	0.002
E29.0 Testicular hyperfunction	0.000	0.998	0.002
E34.8 Other specified endocrine disorders	0.000	0.998	0.002
K12.3 Oral mucositis (ulcerative)	0.000	0.998	0.002
T92.9 Sequelae of unspecified injury of upper limb	0.000	0.998	0.002
E23 Hypofunction and other disorders of pituitary gland	0.000	0.998	0.002
J10.8 Influenza with other manifestations, influenza virus identified	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.000	0.998	0.002
K50.0 Crohn's disease of small intestine	0.002	0.998	0.000
E24 Cushing's syndrome	0.000	0.998	0.002
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.002	0.998	0.000
N95.3 States associated with artificial menopause	0.002	0.998	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.000	0.998	0.002
B02 Zoster [herpes zoster]	0.000	0.998	0.002
E30.9 Disorder of puberty, unspecified	0.000	0.998	0.002
E30.8 Other disorders of puberty	0.000	0.998	0.002
E30.1 Precocious puberty	0.000	0.998	0.002
E30.0 Delayed puberty	0.000	0.998	0.002
E32.9 Disease of thymus, unspecified	0.000	0.998	0.002
E32.8 Other diseases of thymus	0.000	0.998	0.002
E32.1 Abscess of thymus	0.000	0.998	0.002
E32.0 Persistent hyperplasia of thymus	0.000	0.998	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.998	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.998	0.002
D13.0 Oesophagus	0.002	0.998	0.000
G36.0 Neuromyelitis optica [Devic]	0.002	0.998	0.000
U84 Resistance to other antimicrobial drugs	0.002	0.998	0.000
U83 Resistance to other antibiotics	0.002	0.998	0.000
U82 Resistance to betalactam antibiotics	0.002	0.998	0.000
U85 Resistance to antineoplastic drugs	0.002	0.998	0.000
X51.9 Unspecified place	0.000	0.998	0.002
E26.9 Hyperaldosteronism, unspecified	0.000	0.998	0.002
E26.8 Other hyperaldosteronism	0.000	0.998	0.002
E26.1 Secondary hyperaldosteronism	0.000	0.998	0.002
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.002
E31.8 Other polyglandular dysfunction	0.000	0.998	0.002
E31.1 Polyglandular hyperfunction	0.000	0.998	0.002
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.002	0.998	0.000
I28.8 Other specified diseases of pulmonary vessels	0.002	0.998	0.000
G36.9 Acute disseminated demyelination, unspecified	0.002	0.998	0.000
G36.8 Other specified acute disseminated demyelination	0.002	0.998	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.002	0.998	0.000
E07 Other disorders of thyroid	0.002	0.998	0.000
E31.0 Autoimmune polyglandular failure	0.000	0.998	0.002
O02 Other abnormal products of conception	0.000	0.998	0.002
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
K26.3 Acute without haemorrhage or perforation	0.000	0.998	0.002
M86-M90 Other osteopathies	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.000	0.998	0.002
E20.1 Pseudohypoparathyroidism	0.000	0.998	0.002
E20.0 Idiopathic hypoparathyroidism	0.000	0.998	0.002
E34.3 Short stature, not elsewhere classified	0.000	0.998	0.001
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.998	0.002
S70.1 Contusion of thigh	0.000	0.998	0.002
U80.0 Penicillin resistant agent	0.002	0.998	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.998	0.002
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.001
E25.8 Other adrenogenital disorders	0.000	0.998	0.001
E26.0 Primary hyperaldosteronism	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.000	0.998	0.002
I51.8 Other ill-defined heart diseases	0.002	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.002
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.002
K50.8 Other Crohn's disease	0.002	0.998	0.000
T90.9 Sequelae of unspecified injury of head	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
B02.8 Zoster with other complications	0.000	0.998	0.002
B02.2 Zoster with other nervous system involvement	0.000	0.998	0.002
E24.8 Other Cushing's syndrome	0.000	0.998	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.998	0.002
E24.3 Ectopic ACTH syndrome	0.000	0.998	0.002
E24.1 Nelson's syndrome	0.000	0.998	0.002
K81.0 Acute cholecystitis	0.000	0.998	0.002
B02.7 Disseminated zoster	0.000	0.998	0.001
B02.0 Zoster encephalitis	0.000	0.998	0.001
E23.6 Other disorders of pituitary gland	0.000	0.998	0.002
K50.9 Crohn's disease, unspecified	0.002	0.998	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
E23.2 Diabetes insipidus	0.000	0.998	0.002
U82.9 Resistance to betalactam antibiotics, unspecified	0.001	0.998	0.000
U82.8 Resistance to other betalactam antibiotics	0.001	0.998	0.000
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.001	0.998	0.000
U82.1 Resistance to methicillin	0.001	0.998	0.000
U82.0 Resistance to penicillin	0.001	0.998	0.000
U83.9 Resistance to unspecified antibiotic	0.001	0.998	0.000
U83.8 Resistance to other single specified antibiotic	0.001	0.998	0.000
U83.7 Resistance to multiple antibiotics	0.001	0.998	0.000
U83.2 Resistance to quinolones	0.001	0.998	0.000
U83.1 Resistance to other vancomycin related antibiotics	0.001	0.998	0.000
U83.0 Resistance to vancomycin	0.001	0.998	0.000
U84.9 Resistance to unspecified antimicrobial drugs	0.001	0.998	0.000
U84.8 Resistance to other specified antimicrobial drug	0.001	0.998	0.000
U84.7 Resistance to multiple antimicrobial drugs	0.001	0.998	0.000
U84.3 Resistance to tuberculostatic drug(s)	0.001	0.998	0.000
U84.2 Resistance to antiviral drug(s)	0.001	0.998	0.000
U84.1 Resistance to antifungal drug(s)	0.001	0.998	0.000
U84.0 Resistance to antiparasitic drug(s)	0.001	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.998	0.002
E24.2 Drug-induced Cushing's syndrome	0.000	0.998	0.001
K76.7 Hepatorenal syndrome	0.000	0.998	0.002
M25.81 Other specified joint disorders (Shoulder region)	0.001	0.998	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.998	0.001
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
C44.0 Skin of lip	0.000	0.998	0.002
E07.1 Dyshormogenetic goitre	0.001	0.998	0.000
E07.0 Hypersecretion of calcitonin	0.001	0.998	0.000
O02.9 Abnormal product of conception, unspecified	0.000	0.998	0.001
O02.8 Other specified abnormal products of conception	0.000	0.998	0.001
O02.0 Blighted ovum and nonhydatidiform mole	0.000	0.998	0.002
Z04.1 Examination and observation following transport accident	0.002	0.998	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.002	0.998	0.000
C44.7 Skin of lower limb, including hip	0.000	0.998	0.002
E07.8 Other specified disorders of thyroid	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations