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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10965215
log Bayes Factor = 149.273
Chromosome 9   position 22,029,445  (GRCh37) Explore rs10965215 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
H40.9 Glaucoma, unspecified
1.000 0.000 0.000
H40.1 Primary open-angle glaucoma
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
1.000 0.000 0.000
I21.9 Acute myocardial infarction, unspecified
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
1.000 0.000 0.000
I25.2 Old myocardial infarction
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
Z95.5 Presence of coronary angioplasty implant and graft
1.000 0.000 0.000
Z95.1 Presence of aortocoronary bypass graft
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I21 Acute myocardial infarction
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
C44.5 Skin of trunk
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
1.000 0.000 0.000
I20.0 Unstable angina
1.000 0.000 0.000
C71 Malignant neoplasm of brain
0.000 0.000 1.000
C44.3 Skin of other and unspecified parts of face
0.000 0.000 1.000
I22 Subsequent myocardial infarction
1.000 0.000 0.000
I21.4 Acute subendocardial myocardial infarction
1.000 0.000 0.000
H40 Glaucoma
1.000 0.000 0.000
C44.0 Skin of lip
0.000 0.001 0.999
I21.1 Acute transmural myocardial infarction of inferior wall
0.999 0.001 0.000
C71.9 Brain, unspecified
0.000 0.001 0.999
C44.4 Skin of scalp and neck
0.000 0.005 0.995
C44.1 Skin of eyelid, including canthus
0.000 0.005 0.995
C71.1 Frontal lobe
0.000 0.008 0.992
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.010 0.990
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.010 0.990
Chapter II Neoplasms
0.000 0.013 0.987
I22.9 Subsequent myocardial infarction of unspecified site
0.987 0.013 0.000
C44.6 Skin of upper limb, including shoulder
0.000 0.014 0.986
D00-D09 In situ neoplasms
0.000 0.017 0.983
D05 Carcinoma in situ of breast
0.000 0.017 0.983
D05.9 Carcinoma in situ of breast, unspecified
0.000 0.020 0.980
Z95.8 Presence of other cardiac and vascular implants and grafts
0.978 0.022 0.000
I24 Other acute ischaemic heart diseases
0.978 0.022 0.000
C15-C26 Malignant neoplasms of digestive organs
0.000 0.022 0.978
I73.9 Peripheral vascular disease, unspecified
0.974 0.026 0.000
C15 Malignant neoplasm of oesophagus
0.000 0.028 0.972
I21.0 Acute transmural myocardial infarction of anterior wall
0.972 0.028 0.000
I73 Other peripheral vascular diseases
0.972 0.028 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.971 0.029 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.959 0.041 0.000
C15.5 Lower third of oesophagus
0.000 0.041 0.959
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.958 0.042 0.000
I72 Other aneurysm
0.956 0.044 0.000
C71.2 Temporal lobe
0.000 0.047 0.953
Z82.3 Family history of stroke
0.946 0.054 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.945 0.055 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.944 0.056 0.000
C15.9 Oesophagus, unspecified
0.000 0.058 0.942
I24.9 Acute ischaemic heart disease, unspecified
0.939 0.061 0.000
C21 Malignant neoplasm of anus and anal canal
0.000 0.067 0.933
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.075 0.925
Z92.2 Personal history of long-term (current) use of other medicaments
0.924 0.076 0.000
I74 Arterial embolism and thrombosis
0.916 0.084 0.000
C44.2 Skin of ear and external auricular canal
0.000 0.088 0.912
I20.8 Other forms of angina pectoris
0.910 0.090 0.000
I77 Other disorders of arteries and arterioles
0.909 0.091 0.000
C71.3 Parietal lobe
0.000 0.093 0.907
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.907 0.093 0.000
C71.8 Overlapping lesion of brain
0.000 0.095 0.905
I24.8 Other forms of acute ischaemic heart disease
0.902 0.098 0.000
I77.1 Stricture of artery
0.900 0.100 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.103 0.897
I25.5 Ischaemic cardiomyopathy
0.897 0.103 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.121 0.879
I70 Atherosclerosis
0.878 0.122 0.000
C17 Malignant neoplasm of small intestine
0.000 0.128 0.872
D05.7 Other carcinoma in situ of breast
0.000 0.130 0.870
I25.4 Coronary artery aneurysm
0.868 0.132 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.145 0.855
I72.3 Aneurysm of iliac artery
0.851 0.149 0.000
C16 Malignant neoplasm of stomach
0.000 0.157 0.843
I25.3 Aneurysm of heart
0.840 0.160 0.000
H40.0 Glaucoma suspect
0.835 0.165 0.000
D02.0 Larynx
0.000 0.165 0.835
I22.8 Subsequent myocardial infarction of other sites
0.835 0.165 0.000
C71.0 Cerebrum, except lobes and ventricles
0.000 0.168 0.832
C02.9 Tongue, unspecified
0.000 0.178 0.822
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.189 0.811
C21.0 Anus, unspecified
0.000 0.190 0.810
C16.0 Cardia
0.000 0.191 0.809
I21.2 Acute transmural myocardial infarction of other sites
0.808 0.192 0.000
C20 Malignant neoplasm of rectum
0.000 0.198 0.802
I72.0 Aneurysm of carotid artery
0.798 0.202 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.206 0.794
I70.2 Atherosclerosis of arteries of the extremities
0.793 0.207 0.000
I72.1 Aneurysm of artery of upper extremity
0.790 0.210 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.214 0.786
I72.9 Aneurysm of unspecified site
0.779 0.221 0.000
D05.0 Lobular carcinoma in situ
0.000 0.221 0.779
Z95.3 Presence of xenogenic heart valve
0.777 0.223 0.000
I72.4 Aneurysm of artery of lower extremity
0.776 0.224 0.000
I70.1 Atherosclerosis of renal artery
0.766 0.234 0.000
C17.0 Duodenum
0.000 0.248 0.752
C32 Malignant neoplasm of larynx
0.000 0.249 0.751
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.254 0.746
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.256 0.744
I72.8 Aneurysm of other specified arteries
0.742 0.258 0.000
Chapter IX Diseases of the circulatory system
0.739 0.261 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.733 0.267 0.000
I77.0 Arteriovenous fistula, acquired
0.731 0.269 0.000
I72.2 Aneurysm of renal artery
0.731 0.269 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.730 0.270 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.270 0.730
I25.6 Silent myocardial ischaemia
0.726 0.274 0.000
I73.8 Other specified peripheral vascular diseases
0.724 0.276 0.000
C23 Malignant neoplasm of gallbladder
0.000 0.282 0.717
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.717 0.283 0.000
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
I21.X Presumed acute myicardial infaction (unconfirmed)
0.717 0.283 0.000
C71.5 Cerebral ventricle
0.000 0.283 0.717
H40.6 Glaucoma secondary to drugs
0.717 0.283 0.000
C00 Malignant neoplasm of lip
0.000 0.284 0.716
C71.7 Brain stem
0.000 0.287 0.713
C15.0 Cervical part of oesophagus
0.000 0.288 0.712
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.000 0.288 0.711
I74.8 Embolism and thrombosis of other arteries
0.710 0.290 0.000
C02.4 Lingual tonsil
0.000 0.291 0.709
H40.3 Glaucoma secondary to eye trauma
0.706 0.294 0.000
C21.1 Anal canal
0.000 0.295 0.705
C07 Malignant neoplasm of parotid gland
0.000 0.295 0.705
C08.9 Major salivary gland, unspecified
0.000 0.297 0.703
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.700 0.300 0.000
C15.8 Overlapping lesion of oesophagus
0.000 0.303 0.697
C15.2 Abdominal part of oesophagus
0.000 0.303 0.697
C71.6 Cerebellum
0.000 0.307 0.693
C17.9 Small intestine, unspecified
0.000 0.309 0.691
I70.10 Atherosclerosis of renal artery (without gangrene)
0.686 0.314 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.685 0.314 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.685 0.314 0.000
I77.3 Arterial fibromuscular dysplasia
0.682 0.317 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.676 0.324 0.000
C01 Malignant neoplasm of base of tongue
0.000 0.325 0.675
H40.2 Primary angle-closure glaucoma
0.673 0.327 0.000
C32.9 Larynx, unspecified
0.000 0.330 0.670
I21.3 Acute transmural myocardial infarction of unspecified site
0.670 0.330 0.000
C21.2 Cloacogenic zone
0.000 0.331 0.669
C16.5 Lesser curvature of stomach, unspecified
0.000 0.333 0.667
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.666 0.334 0.000
C10 Malignant neoplasm of oropharynx
0.000 0.335 0.665
C17.1 Jejunum
0.000 0.336 0.664
C02.1 Border of tongue
0.000 0.338 0.662
C32.0 Glottis
0.000 0.338 0.662
I74.9 Embolism and thrombosis of unspecified artery
0.660 0.340 0.000
I70.8 Atherosclerosis of other arteries
0.655 0.345 0.000
D04 Carcinoma in situ of skin
0.000 0.345 0.655
C05 Malignant neoplasm of palate
0.000 0.348 0.652
I77.5 Necrosis of artery
0.651 0.348 0.000
I77.4 Coeliac artery compression syndrome
0.651 0.348 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.000 0.349 0.651
I74.0 Embolism and thrombosis of abdominal aorta
0.648 0.352 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.648 0.352 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.646 0.354 0.000
D02.4 Respiratory system, unspecified
0.000 0.357 0.643
D02.3 Other parts of respiratory system
0.000 0.357 0.643
D02.2 Bronchus and lung
0.000 0.357 0.643
D02.1 Trachea
0.000 0.357 0.643
C02.2 Ventral surface of tongue
0.000 0.358 0.642
Z82.1 Family history of blindness and visual loss
0.641 0.359 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.359 0.641
H40.8 Other glaucoma
0.640 0.360 0.000
C15.1 Thoracic part of oesophagus
0.000 0.360 0.640
C08.0 Submandibular gland
0.000 0.362 0.638
D01.2 Rectum
0.000 0.365 0.635
D05.1 Intraductal carcinoma in situ
0.000 0.366 0.634
C13 Malignant neoplasm of hypopharynx
0.000 0.368 0.632
C02.8 Overlapping lesion of tongue
0.000 0.369 0.630
C02.3 Anterior two-thirds of tongue, part unspecified
0.000 0.369 0.630
C02.0 Dorsal surface of tongue
0.000 0.369 0.630
C04 Malignant neoplasm of floor of mouth
0.000 0.371 0.629
C17.8 Overlapping lesion of small intestine
0.000 0.375 0.625
C17.3 Meckel's diverticulum
0.000 0.375 0.625
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.622 0.378 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.618 0.382 0.000
C15.3 Upper third of oesophagus
0.000 0.382 0.617
C17.2 Ileum
0.000 0.383 0.617
H40.4 Glaucoma secondary to eye inflammation
0.613 0.386 0.000
C03 Malignant neoplasm of gum
0.000 0.390 0.610
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.391 0.609
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.609 0.391 0.000
Z82.2 Family history of deafness and hearing loss
0.608 0.392 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.392 0.608
Z95.0 Presence of cardiac pacemaker
0.608 0.392 0.000
C16.1 Fundus of stomach
0.000 0.394 0.606
C71.4 Occipital lobe
0.000 0.396 0.604
I24.1 Dressler's syndrome
0.604 0.396 0.000
C70 Malignant neoplasm of meninges
0.000 0.396 0.604
C31 Malignant neoplasm of accessory sinuses
0.000 0.398 0.602
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.399 0.601
C12 Malignant neoplasm of pyriform sinus
0.000 0.399 0.601
C30 Malignant neoplasm of nasal cavity and middle ear
0.000 0.399 0.601
C16.8 Overlapping lesion of stomach
0.000 0.399 0.601
I70.9 Generalised and unspecified atherosclerosis
0.600 0.400 0.000
C11 Malignant neoplasm of nasopharynx
0.000 0.400 0.599
I23 Certain current complications following acute myocardial infarction
0.594 0.406 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.592 0.408 0.000
D01.0 Colon
0.000 0.409 0.591
C14.0 Pharynx, unspecified
0.000 0.410 0.590
C16.6 Greater curvature of stomach, unspecified
0.000 0.410 0.590
D04.3 Skin of other and unspecified parts of face
0.000 0.416 0.584
C37 Malignant neoplasm of thymus
0.000 0.417 0.583
C08.8 Overlapping lesion of major salivary glands
0.000 0.418 0.582
C08.1 Sublingual gland
0.000 0.418 0.582
D04.2 Skin of ear and external auricular canal
0.000 0.426 0.574
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.000 0.430 0.570
D07.2 Vagina
0.000 0.430 0.570
C44.7 Skin of lower limb, including hip
0.000 0.431 0.569
C16.9 Stomach, unspecified
0.000 0.433 0.567
D01.9 Digestive organ, unspecified
0.000 0.436 0.564
D01.7 Other specified digestive organs
0.000 0.436 0.564
D01.5 Liver, gallbladder and bile ducts
0.000 0.436 0.564
D01.4 Other and unspecified parts of intestine
0.000 0.436 0.564
D01.1 Rectosigmoid junction
0.000 0.436 0.564
C16.4 Pylorus
0.000 0.436 0.564
D07.5 Prostate
0.000 0.436 0.564
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.000 0.437 0.563
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.561 0.439 0.000
H40.5 Glaucoma secondary to other eye disorders
0.556 0.444 0.000
C00.0 External upper lip
0.000 0.445 0.555
C32.1 Supraglottis
0.000 0.446 0.554
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.450 0.550
I70.11 Atherosclerosis of renal artery (with gangrene)
0.549 0.451 0.000
C00.1 External lower lip
0.000 0.451 0.549
D01.3 Anus and anal canal
0.000 0.451 0.549
C38 Malignant neoplasm of heart, mediastinum and pleura
0.000 0.452 0.548
D07.1 Vulva
0.000 0.455 0.545
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.000 0.459 0.541
C32.8 Overlapping lesion of larynx
0.000 0.462 0.538
C32.3 Laryngeal cartilage
0.000 0.462 0.538
C32.2 Subglottis
0.000 0.462 0.538
I73.0 Raynaud's syndrome
0.536 0.464 0.000
D07.6 Other and unspecified male genital organs
0.000 0.465 0.535
D07.3 Other and unspecified female genital organs
0.000 0.465 0.535
D07.0 Endometrium
0.000 0.465 0.535
D04.9 Skin, unspecified
0.000 0.466 0.534
D09 Carcinoma in situ of other and unspecified sites
0.000 0.466 0.534
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.000 0.466 0.533
I77.2 Rupture of artery
0.532 0.468 0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx
0.000 0.476 0.523
C14.2 Waldeyer's ring
0.000 0.476 0.523
I00-I02 Acute rheumatic fever
0.520 0.480 0.000
C33 Malignant neoplasm of trachea
0.000 0.481 0.518
C00.8 Overlapping lesion of lip
0.000 0.487 0.513
C00.6 Commissure of lip
0.000 0.487 0.513
C00.5 Lip, unspecified, inner aspect
0.000 0.487 0.513
C00.4 Lower lip, inner aspect
0.000 0.487 0.513
C00.3 Upper lip, inner aspect
0.000 0.487 0.513
C00.2 External lip, unspecified
0.000 0.487 0.513
C72.0 Spinal cord
0.000 0.488 0.512
I74.5 Embolism and thrombosis of iliac artery
0.512 0.488 0.000
C72.9 Central nervous system, unspecified
0.000 0.490 0.510
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.000 0.490 0.510
C72.5 Other and unspecified cranial nerves
0.000 0.490 0.510
C72.4 Acoustic nerve
0.000 0.490 0.510
C72.3 Optic nerve
0.000 0.490 0.510
C72.2 Olfactory nerve
0.000 0.490 0.510
C72.1 Cauda equina
0.000 0.490 0.510
C05.9 Palate, unspecified
0.000 0.498 0.502
I79.1 Aortitis in diseases classified elsewhere
0.502 0.498 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.502 0.498 0.000
D07.4 Penis
0.000 0.499 0.501
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.501 0.498
C06.0 Cheek mucosa
0.000 0.504 0.496
I70.80 Atherosclerosis of other arteries (without gangrene)
0.495 0.505 0.000
D06 Carcinoma in situ of cervix uteri
0.000 0.506 0.494
C15.4 Middle third of oesophagus
0.000 0.513 0.487
C00.9 Lip, unspecified
0.000 0.513 0.487
C06.2 Retromolar area
0.000 0.514 0.486
C10.9 Oropharynx, unspecified
0.000 0.521 0.479
C10.8 Overlapping lesion of oropharynx
0.000 0.523 0.477
C10.4 Branchial cleft
0.000 0.523 0.477
C10.3 Posterior wall of oropharynx
0.000 0.523 0.477
C10.2 Lateral wall of oropharynx
0.000 0.523 0.477
C10.1 Anterior surface of epiglottis
0.000 0.523 0.477
C10.0 Vallecula
0.000 0.523 0.477
Z95.2 Presence of prosthetic heart valve
0.473 0.527 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.470 0.530 0.000
D04.8 Skin of other sites
0.000 0.530 0.470
D04.0 Skin of lip
0.000 0.530 0.470
C69 Malignant neoplasm of eye and adnexa
0.000 0.530 0.470
D04.6 Skin of upper limb, including shoulder
0.000 0.531 0.469
C05.8 Overlapping lesion of palate
0.000 0.532 0.467
C05.2 Uvula
0.000 0.532 0.467
C13.0 Postcricoid region
0.000 0.533 0.467
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.000 0.533 0.466
C06.1 Vestibule of mouth
0.000 0.533 0.466
C31.0 Maxillary sinus
0.000 0.536 0.464
C30.0 Nasal cavity
0.000 0.537 0.463
C16.3 Pyloric antrum
0.000 0.538 0.462
C24.8 Overlapping lesion of biliary tract
0.000 0.540 0.459
C04.9 Floor of mouth, unspecified
0.000 0.542 0.457
I70.0 Atherosclerosis of aorta
0.457 0.543 0.000
C24.9 Biliary tract, unspecified
0.000 0.544 0.456
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.000 0.545 0.455
C13.8 Overlapping lesion of hypopharynx
0.000 0.547 0.453
C13.2 Posterior wall of hypopharynx
0.000 0.547 0.453
C13.1 Aryepiglottic fold, hypopharyngeal aspect
0.000 0.547 0.453
C04.8 Overlapping lesion of floor of mouth
0.000 0.549 0.451
C04.1 Lateral floor of mouth
0.000 0.549 0.451
C16.2 Body of stomach
0.000 0.553 0.447
C24.0 Extrahepatic bile duct
0.000 0.554 0.446
C50-C50 Malignant neoplasm of breast
0.000 0.557 0.443
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.441 0.559 0.000
C05.0 Hard palate
0.000 0.559 0.441
C05.1 Soft palate
0.000 0.559 0.441
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.560 0.440
C03.9 Gum, unspecified
0.000 0.563 0.437
C03.0 Upper gum
0.000 0.563 0.437
D00.2 Stomach
0.000 0.564 0.436
C09 Malignant neoplasm of tonsil
0.000 0.564 0.435
C70.9 Meninges, unspecified
0.000 0.567 0.433
C70.1 Spinal meninges
0.000 0.567 0.433
C40.0 Scapula and long bones of upper limb
0.000 0.567 0.433
C31.9 Accessory sinus, unspecified
0.000 0.568 0.431
C31.8 Overlapping lesion of accessory sinuses
0.000 0.568 0.431
C31.3 Sphenoidal sinus
0.000 0.568 0.431
C31.2 Frontal sinus
0.000 0.568 0.431
C31.1 Ethmoidal sinus
0.000 0.568 0.431
C30.1 Middle ear
0.000 0.569 0.431
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.430 0.570 0.000
C11.8 Overlapping lesion of nasopharynx
0.000 0.570 0.430
C11.3 Anterior wall of nasopharynx
0.000 0.570 0.430
C11.2 Lateral wall of nasopharynx
0.000 0.570 0.430
C11.1 Posterior wall of nasopharynx
0.000 0.570 0.430
C11.0 Superior wall of nasopharynx
0.000 0.570 0.430
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.426 0.574 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.426 0.574 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.426 0.574 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.426 0.574 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.426 0.574 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.426 0.574 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.426 0.574 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.422 0.577 0.000
D04.4 Skin of scalp and neck
0.000 0.579 0.421
C24.1 Ampulla of Vater
0.000 0.580 0.420
H40-H42 Glaucoma
0.418 0.582 0.000
C60-C63 Malignant neoplasms of male genital organs
0.000 0.583 0.417
I77.8 Other specified disorders of arteries and arterioles
0.414 0.585 0.000
I20.1 Angina pectoris with documented spasm
0.410 0.589 0.000
C04.0 Anterior floor of mouth
0.000 0.590 0.410
C39.9 Ill-defined sites within the respiratory system
0.000 0.591 0.408
C39.8 Overlapping lesion of respiratory and intrathoracic organs
0.000 0.591 0.408
C39.0 Upper respiratory tract, part unspecified
0.000 0.591 0.408
C41.9 Bone and articular cartilage, unspecified
0.000 0.592 0.408
C13.9 Hypopharynx, unspecified
0.000 0.595 0.405
D00.0 Lip, oral cavity and pharynx
0.000 0.596 0.404
C40.2 Long bones of lower limb
0.000 0.596 0.404
C40.9 Bone and articular cartilage of limb, unspecified
0.000 0.596 0.404
C40.8 Overlapping lesion of bone and articular cartilage of limbs
0.000 0.596 0.404
C40.3 Short bones of lower limb
0.000 0.596 0.404
C40.1 Short bones of upper limb
0.000 0.596 0.404
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.400 0.600 0.000
C41.4 Pelvic bones, sacrum and coccyx
0.000 0.602 0.398
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.000 0.605 0.394
C46 Kaposi's sarcoma
0.000 0.605 0.394
C38.8 Overlapping lesion of heart, mediastinum and pleura
0.000 0.607 0.393
C38.2 Posterior mediastinum
0.000 0.607 0.393
C38.1 Anterior mediastinum
0.000 0.607 0.393
C38.0 Heart
0.000 0.607 0.393
C38.4 Pleura
0.000 0.610 0.390
C06.9 Mouth, unspecified
0.000 0.610 0.389
C41.2 Vertebral column
0.000 0.611 0.389
C41.8 Overlapping lesion of bone and articular cartilage
0.000 0.612 0.388
C41.3 Ribs, sternum and clavicle
0.000 0.612 0.388
D04.1 Skin of eyelid, including canthus
0.000 0.613 0.387
C03.1 Lower gum
0.000 0.616 0.384
D09.9 Carcinoma in situ, unspecified
0.000 0.616 0.384
D06.0 Endocervix
0.000 0.617 0.383
D09.3 Thyroid and other endocrine glands
0.000 0.617 0.383
D09.2 Eye
0.000 0.617 0.383
C41.0 Bones of skull and face
0.000 0.617 0.383
C42.4 hematopoietic and reticuloendothelial systems: Hematopoietic system, NOS (ICD-O-3 specific)
0.000 0.617 0.382
C42.3 hematopoietic and reticuloendothelial systems: Reticuloendothelial system, NOS (ICD-O-3 specific)
0.000 0.617 0.382
C42.2 hematopoietic and reticuloendothelial systems: spleen (ICD-O-3 specific)
0.000 0.617 0.382
C42.1 hematopoietic and reticuloendothelial systems: bone marrow (ICD-O-3 specific)
0.000 0.617 0.382
C42.0 hematopoietic and reticuloendothelial systems: blood (ICD-O-3 specific)
0.000 0.617 0.382
D00.1 Oesophagus
0.000 0.618 0.381
C38.3 Mediastinum, part unspecified
0.000 0.625 0.375
I02 Rheumatic chorea
0.373 0.627 0.000
I01 Rheumatic fever with heart involvement
0.373 0.627 0.000
D09.7 Carcinoma in situ of other specified sites
0.000 0.630 0.370
C48.0 Retroperitoneum
0.000 0.630 0.370
C41.1 Mandible
0.000 0.631 0.369
C48.2 Peritoneum, unspecified
0.000 0.632 0.368
C11.9 Nasopharynx, unspecified
0.000 0.633 0.366
I00 Rheumatic fever without mention of heart involvement
0.362 0.638 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.001 0.639 0.360
C26.8 Overlapping lesion of digestive system
0.000 0.642 0.357
C26.1 Spleen
0.000 0.642 0.357
C69.6 Orbit
0.000 0.643 0.357
D06.7 Other parts of cervix
0.000 0.646 0.354
D06.1 Exocervix
0.000 0.647 0.353
D09.1 Other and unspecified urinary organs
0.000 0.650 0.349
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.339 0.661 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.338 0.662 0.001
C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.662 0.338
C69.8 Overlapping lesion of eye and adnexa
0.000 0.663 0.337
C69.5 Lachrymal gland and duct
0.000 0.663 0.337
C69.4 Ciliary body
0.000 0.663 0.337
C69.2 Retina
0.000 0.663 0.337
C69.1 Cornea
0.000 0.663 0.337
I70.01 Atherosclerosis of aorta (with gangrene)
0.327 0.672 0.000
C70.0 Cerebral meninges
0.001 0.673 0.327
I71 Aortic aneurysm and dissection
0.326 0.674 0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum
0.000 0.674 0.326
C60 Malignant neoplasm of penis
0.000 0.677 0.323
C26.9 Ill-defined sites within the digestive system
0.000 0.683 0.317
I60-I69 Cerebrovascular diseases
0.313 0.687 0.000
C09.8 Overlapping lesion of tonsil
0.000 0.687 0.312
C09.0 Tonsillar fossa
0.000 0.687 0.312
C69.9 Eye, unspecified
0.000 0.692 0.308
D03 Melanoma in situ
0.000 0.692 0.308
C63 Malignant neoplasm of other and unspecified male genital organs
0.000 0.692 0.308
I23.8 Other current complications following acute myocardial infarction
0.302 0.697 0.001
C48.1 Specified parts of peritoneum
0.000 0.700 0.300
H42 Glaucoma in diseases classified elsewhere
0.299 0.700 0.000
C09.1 Tonsillar pillar (anterior) (posterior)
0.000 0.701 0.299
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.299 0.701 0.000
C69.0 Conjunctiva
0.000 0.704 0.296
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.293 0.707 0.001
C45 Mesothelioma
0.000 0.707 0.293
D09.0 Bladder
0.000 0.712 0.287
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.286 0.714 0.000
I05-I09 Chronic rheumatic heart diseases
0.285 0.715 0.000
C46.9 Kaposi's sarcoma, unspecified
0.000 0.717 0.283
C46.8 Kaposi's sarcoma of multiple organs
0.000 0.717 0.283
C46.7 Kaposi's sarcoma of other sites
0.000 0.717 0.283
C46.3 Kaposi's sarcoma of lymph nodes
0.000 0.717 0.283
C46.2 Kaposi's sarcoma of palate
0.000 0.717 0.283
C46.1 Kaposi's sarcoma of soft tissue
0.000 0.717 0.283
C46.0 Kaposi's sarcoma of skin
0.000 0.717 0.283
C47.9 Peripheral nerves and autonomic nervous system, unspecified
0.000 0.717 0.283
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system
0.000 0.717 0.283
C47.6 Peripheral nerves of trunk, unspecified
0.000 0.717 0.283
C47.5 Peripheral nerves of pelvis
0.000 0.717 0.283
C47.4 Peripheral nerves of abdomen
0.000 0.717 0.283
C47.3 Peripheral nerves of thorax
0.000 0.717 0.283
C47.2 Peripheral nerves of lower limb, including hip
0.000 0.717 0.283
C47.1 Peripheral nerves of upper limb, including shoulder
0.000 0.717 0.283
C47.0 Peripheral nerves of head, face and neck
0.000 0.717 0.283
I67 Other cerebrovascular diseases
0.283 0.717 0.000
E78.0 Pure hypercholesterolaemia
0.279 0.721 0.000
I67.9 Cerebrovascular disease, unspecified
0.276 0.724 0.000
C60.9 Penis, unspecified
0.000 0.729 0.271
I01.9 Acute rheumatic heart disease, unspecified
0.267 0.733 0.000
I01.8 Other acute rheumatic heart disease
0.267 0.733 0.000
I01.2 Acute rheumatic myocarditis
0.267 0.733 0.000
I01.1 Acute rheumatic endocarditis
0.267 0.733 0.000
I01.0 Acute rheumatic pericarditis
0.267 0.733 0.000
I02.9 Rheumatic chorea without heart involvement
0.267 0.733 0.000
I02.0 Rheumatic chorea with heart involvement
0.267 0.733 0.000
C74 Malignant neoplasm of adrenal gland
0.001 0.734 0.266
C62 Malignant neoplasm of testis
0.000 0.739 0.261
D04.5 Skin of trunk
0.000 0.740 0.259
I67.0 Dissection of cerebral arteries, nonruptured
0.258 0.742 0.000
I78 Diseases of capillaries
0.255 0.744 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.254 0.745 0.000
D03.4 Melanoma in situ of scalp and neck
0.000 0.746 0.254
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.253 0.747 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.250 0.750 0.000
I62 Other nontraumatic intracranial haemorrhage
0.247 0.753 0.000
K62 Other diseases of anus and rectum
0.000 0.754 0.246
K62.1 Rectal polyp
0.000 0.756 0.244
K62.8 Other specified diseases of anus and rectum
0.000 0.758 0.242
K62.4 Stenosis of anus and rectum
0.000 0.758 0.242
C49 Malignant neoplasm of other connective and soft tissue
0.000 0.759 0.241
K62.0 Anal polyp
0.000 0.759 0.241
C45.7 Mesothelioma of other sites
0.000 0.761 0.239
D03.7 Melanoma in situ of lower limb, including hip
0.000 0.762 0.238
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.238 0.762 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.234 0.766 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.234 0.766 0.000
C60.8 Overlapping lesion of penis
0.000 0.768 0.232
C60.2 Body of penis
0.000 0.768 0.232
C26.0 Intestinal tract, part unspecified
0.000 0.768 0.231
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.231 0.769 0.000
I65.2 Occlusion and stenosis of carotid artery
0.231 0.769 0.000
C60.0 Prepuce
0.000 0.769 0.231
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.230 0.770 0.000
I66.2 Occlusion and stenosis of posterior cerebral artery
0.230 0.770 0.000
C63.2 Scrotum
0.000 0.771 0.229
C18 Malignant neoplasm of colon
0.000 0.778 0.222
I09 Other rheumatic heart diseases
0.221 0.779 0.000
D03.9 Melanoma in situ, unspecified
0.000 0.779 0.221
D03.0 Melanoma in situ of lip
0.000 0.779 0.221
C63.9 Male genital organ, unspecified
0.000 0.779 0.221
C63.8 Overlapping lesion of male genital organs
0.000 0.779 0.221
C63.7 Other specified male genital organs
0.000 0.779 0.221
C63.1 Spermatic cord
0.000 0.779 0.221
C63.0 Epididymis
0.000 0.779 0.221
D03.1 Melanoma in situ of eyelid, including canthus
0.000 0.781 0.219
I66.3 Occlusion and stenosis of cerebellar arteries
0.216 0.784 0.000
H42.8 Glaucoma in other diseases classified elsewhere
0.215 0.785 0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases
0.215 0.785 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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