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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs146534110
log Bayes Factor = 28.6815
Chromosome 6   position 160,578,069  (GRCh37) Explore rs146534110 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20.0 Unstable angina
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.997 0.003 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.997 0.003 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.995 0.005 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.995 0.005 0.000
E70-E90 Metabolic disorders
0.990 0.010 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.988 0.012 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.988 0.012 0.000
Chapter X Diseases of the respiratory system
0.987 0.013 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.985 0.015 0.000
J40-J47 Chronic lower respiratory diseases
0.982 0.018 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.978 0.022 0.000
J47 Bronchiectasis
0.977 0.023 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.976 0.024 0.000
E78.0 Pure hypercholesterolaemia
0.975 0.025 0.000
Z95.1 Presence of aortocoronary bypass graft
0.970 0.030 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.966 0.034 0.000
E00-E07 Disorders of thyroid gland
0.965 0.035 0.000
M45-M49 Spondylopathies
0.963 0.037 0.000
I21 Acute myocardial infarction
0.962 0.038 0.000
M05-M14 Inflammatory polyarthropathies
0.961 0.039 0.000
M15-M19 Arthrosis
0.956 0.044 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.950 0.050 0.000
E03 Other hypothyroidism
0.945 0.055 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.944 0.056 0.000
R00 Abnormalities of heart beat
0.940 0.060 0.000
M19 Other arthrosis
0.937 0.063 0.000
R47-R49 Symptoms and signs involving speech and voice
0.934 0.066 0.000
E03.9 Hypothyroidism, unspecified
0.931 0.069 0.000
M47 Spondylosis
0.927 0.073 0.000
R07 Pain in throat and chest
0.923 0.077 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.916 0.084 0.000
T81 Complications of procedures, not elsewhere classified
0.913 0.087 0.000
Z85 Personal history of malignant neoplasm
0.911 0.089 0.000
M13 Other arthritis
0.911 0.089 0.000
I20.8 Other forms of angina pectoris
0.911 0.089 0.000
M19.9 Arthrosis, unspecified
0.910 0.090 0.000
R07.4 Chest pain, unspecified
0.907 0.093 0.000
Z98 Other postsurgical states
0.904 0.096 0.000
E78.5 Hyperlipidaemia, unspecified
0.900 0.100 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.897 0.103 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.895 0.105 0.000
I30-I52 Other forms of heart disease
0.894 0.106 0.000
M47.8 Other spondylosis
0.893 0.107 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.890 0.109 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.887 0.113 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.884 0.116 0.000
L03 Cellulitis
0.883 0.117 0.000
T66-T78 Other and unspecified effects of external causes
0.882 0.118 0.000
M65-M68 Disorders of synovium and tendon
0.881 0.119 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.878 0.122 0.000
M13.9 Arthritis, unspecified
0.875 0.125 0.000
W00-W19 Falls
0.873 0.127 0.000
Chapter II Neoplasms
0.870 0.130 0.000
I25.2 Old myocardial infarction
0.868 0.132 0.000
I22 Subsequent myocardial infarction
0.866 0.133 0.000
L05 Pilonidal cyst
0.866 0.134 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.864 0.136 0.000
J44 Other chronic obstructive pulmonary disease
0.864 0.136 0.000
M70-M79 Other soft tissue disorders
0.864 0.136 0.000
M50-M54 Other dorsopathies
0.859 0.141 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.859 0.141 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.858 0.142 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.854 0.146 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.854 0.146 0.000
L82 Seborrhoeic keratosis
0.852 0.148 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.849 0.151 0.000
R49 Voice disturbances
0.847 0.153 0.000
C64-C68 Malignant neoplasms of urinary tract
0.846 0.154 0.000
I42 Cardiomyopathy
0.845 0.155 0.000
R00.1 Bradycardia, unspecified
0.838 0.162 0.000
R02 Gangrene, not elsewhere classified
0.835 0.165 0.000
S80-S89 Injuries to the knee and lower leg
0.834 0.166 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.833 0.167 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.832 0.168 0.000
M47.82 Other spondylosis (Cervical region)
0.830 0.170 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.830 0.170 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.826 0.174 0.000
Z98.0 Intestinal bypass and anastomosis status
0.824 0.176 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.822 0.178 0.000
I21.4 Acute subendocardial myocardial infarction
0.819 0.181 0.000
R00.2 Palpitations
0.813 0.187 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.812 0.188 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.810 0.190 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.809 0.191 0.000
S70-S79 Injuries to the hip and thigh
0.809 0.191 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.807 0.193 0.000
I21.9 Acute myocardial infarction, unspecified
0.806 0.194 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.805 0.195 0.000
C67 Malignant neoplasm of bladder
0.803 0.197 0.000
M46 Other inflammatory spondylopathies
0.802 0.198 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.802 0.198 0.000
R47 Speech disturbances, not elsewhere classified
0.802 0.198 0.000
E83 Disorders of mineral metabolism
0.801 0.199 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.800 0.200 0.000
E20-E35 Disorders of other endocrine glands
0.800 0.200 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.798 0.202 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.798 0.202 0.000
T78 Adverse effects, not elsewhere classified
0.798 0.202 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.793 0.207 0.000
I20.1 Angina pectoris with documented spasm
0.793 0.207 0.000
Chapter VIII Diseases of the ear and mastoid process
0.790 0.210 0.000
M06 Other rheumatoid arthritis
0.788 0.212 0.000
Z89 Acquired absence of limb
0.787 0.213 0.000
I42.0 Dilated cardiomyopathy
0.785 0.215 0.000
R49.0 Dysphonia
0.785 0.215 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.784 0.216 0.000
R26 Abnormalities of gait and mobility
0.781 0.219 0.000
L05.9 Pilonidal cyst without abscess
0.780 0.220 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.780 0.220 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.779 0.221 0.000
M19.0 Primary arthrosis of other joints
0.778 0.222 0.000
W19 Unspecified fall
0.778 0.222 0.000
E78.2 Mixed hyperlipidaemia
0.775 0.225 0.000
J60-J70 Lung diseases due to external agents
0.775 0.225 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.775 0.225 0.000
Y86 Sequelae of other accidents
0.773 0.227 0.000
J40 Bronchitis, not specified as acute or chronic
0.772 0.228 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.772 0.228 0.000
T82.1 Mechanical complication of cardiac electronic device
0.772 0.228 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.771 0.229 0.000
L03.3 Cellulitis of trunk
0.771 0.229 0.000
S50-S59 Injuries to the elbow and forearm
0.770 0.230 0.000
E65-E68 Obesity and other hyperalimentation
0.769 0.231 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.769 0.231 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.769 0.231 0.000
Z87 Personal history of other diseases and conditions
0.766 0.234 0.000
R00.0 Tachycardia, unspecified
0.766 0.234 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.765 0.235 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.762 0.238 0.000
W20-W49 Exposure to inanimate mechanical forces
0.762 0.238 0.000
I24 Other acute ischaemic heart diseases
0.761 0.239 0.000
R03.1 Nonspecific low blood-pressure reading
0.760 0.240 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.759 0.241 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.759 0.241 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.758 0.242 0.000
V20-V29 Motorcycle rider injured in transport accident
0.757 0.243 0.000
E07 Other disorders of thyroid
0.757 0.243 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.756 0.244 0.000
R25 Abnormal involuntary movements
0.755 0.245 0.000
Z95.4 Presence of other heart-valve replacement
0.754 0.246 0.000
M65 Synovitis and tenosynovitis
0.751 0.249 0.000
I74 Arterial embolism and thrombosis
0.751 0.249 0.000
Chapter XIV Diseases of the genitourinary system
0.750 0.250 0.000
I34 Nonrheumatic mitral valve disorders
0.750 0.250 0.000
S10-S19 Injuries to the neck
0.749 0.251 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.749 0.251 0.000
J46 Status asthmaticus
0.748 0.252 0.000
M86-M90 Other osteopathies
0.747 0.253 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.747 0.253 0.000
I60-I69 Cerebrovascular diseases
0.746 0.254 0.000
J00-J06 Acute upper respiratory infections
0.746 0.254 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.745 0.255 0.000
I47 Paroxysmal tachycardia
0.745 0.255 0.000
I73 Other peripheral vascular diseases
0.743 0.257 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.741 0.259 0.000
M13.98 Arthritis, unspecified (Other)
0.741 0.259 0.000
Z43 Attention to artificial openings
0.741 0.259 0.000
M47.9 Spondylosis, unspecified
0.740 0.259 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.740 0.260 0.000
M54 Dorsalgia
0.740 0.260 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.740 0.260 0.000
M50 Cervical disk disorders
0.738 0.262 0.000
V10-V19 Pedal cyclist injured in transport accident
0.736 0.264 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.729 0.271 0.000
S00-S09 Injuries to the head
0.729 0.271 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.728 0.272 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.727 0.273 0.000
I50 Heart failure
0.727 0.273 0.000
C67.9 Bladder, unspecified
0.727 0.273 0.000
M07 Psoriatic and enteropathic arthropathies
0.727 0.273 0.000
L03.0 Cellulitis of finger and toe
0.727 0.273 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.726 0.274 0.000
E50-E64 Other nutritional deficiencies
0.725 0.275 0.000
R20 Disturbances of skin sensation
0.725 0.275 0.000
Z99.8 Dependence on other enabling machines and devices
0.724 0.276 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.722 0.278 0.000
I25.5 Ischaemic cardiomyopathy
0.721 0.279 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.721 0.279 0.000
M67 Other disorders of synovium and tendon
0.718 0.282 0.000
J95-J99 Other diseases of the respiratory system
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter I Certain infectious and parasitic diseases
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.284 0.000
T86 Failure and rejection of transplanted organs and tissues
0.716 0.284 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.284 0.000
E40-E46 Malnutrition
0.715 0.285 0.000
S82 Fracture of lower leg, including ankle
0.715 0.285 0.000
T79-T79 Certain early complications of trauma
0.714 0.285 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.714 0.286 0.000
Z84 Family history of other conditions
0.714 0.286 0.000
Z81 Family history of mental and behavioural disorders
0.714 0.286 0.000
M47.89 Other spondylosis (Site unspecified)
0.714 0.286 0.000
Chapter XXII Codes for special purposes
0.713 0.286 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.713 0.286 0.000
T93 Sequelae of injuries of lower limb
0.713 0.287 0.000
M19.1 Posttraumatic arthrosis of other joints
0.712 0.288 0.000
L40-L45 Papulosquamous disorders
0.712 0.288 0.000
M11 Other crystal arthropathies
0.711 0.288 0.000
Z95.3 Presence of xenogenic heart valve
0.711 0.289 0.000
S60-S69 Injuries to the wrist and hand
0.711 0.289 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.710 0.290 0.000
E88 Other metabolic disorders
0.710 0.290 0.000
E85 Amyloidosis
0.710 0.290 0.000
E84 Cystic fibrosis
0.710 0.290 0.000
E79 Disorders of purine and pyrimidine metabolism
0.710 0.290 0.000
E77 Disorders of glycoprotein metabolism
0.710 0.290 0.000
E76 Disorders of glycosaminoglycan metabolism
0.710 0.290 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.710 0.290 0.000
E74 Other disorders of carbohydrate metabolism
0.710 0.290 0.000
E73 Lactose intolerance
0.710 0.290 0.000
E72 Other disorders of amino-acid metabolism
0.710 0.290 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.710 0.290 0.000
E70 Disorders of aromatic amino-acid metabolism
0.710 0.290 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.710 0.290 0.000
Z41 Procedures for purposes other than remedying health state
0.709 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X60-X84 Intentional self-harm
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.709 0.291 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
W50-W64 Exposure to animate mechanical forces
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
E78.8 Other disorders of lipoprotein metabolism
0.708 0.292 0.000
E78.6 Lipoprotein deficiency
0.708 0.292 0.000
E78.4 Other hyperlipidaemia
0.708 0.292 0.000
E78.3 Hyperchylomicronaemia
0.708 0.292 0.000
E78.1 Pure hyperglyceridaemia
0.708 0.292 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.708 0.292 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.707 0.292 0.000
I42.9 Cardiomyopathy, unspecified
0.705 0.295 0.000
Z98.8 Other specified postsurgical states
0.704 0.295 0.000
J41 Simple and mucopurulent chronic bronchitis
0.704 0.295 0.000
J42 Unspecified chronic bronchitis
0.704 0.295 0.000
Z45 Adjustment and management of implanted device
0.704 0.296 0.000
M80-M85 Disorders of bone density and structure
0.703 0.297 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.701 0.299 0.000
L10-L14 Bullous disorders
0.701 0.299 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.700 0.300 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.700 0.300 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.700 0.300 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.700 0.300 0.000
Z82.2 Family history of deafness and hearing loss
0.700 0.300 0.000
Z82.1 Family history of blindness and visual loss
0.700 0.300 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.700 0.300 0.000
D00-D09 In situ neoplasms
0.699 0.301 0.000
I73.9 Peripheral vascular disease, unspecified
0.699 0.301 0.000
S90-S99 Injuries to the ankle and foot
0.698 0.302 0.000
T88.4 Failed or difficult intubation
0.697 0.302 0.000
R87 Abnormal findings in specimens from female genital organs
0.697 0.303 0.000
Z93 Artificial opening status
0.697 0.303 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.697 0.303 0.000
L05.0 Pilonidal cyst with abscess
0.697 0.303 0.000
M05 Seropositive rheumatoid arthritis
0.695 0.305 0.000
I51 Complications and ill-defined descriptions of heart disease
0.695 0.305 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.694 0.306 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.694 0.306 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.693 0.307 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.692 0.308 0.000
E00 Congenital iodine-deficiency syndrome
0.692 0.308 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.692 0.308 0.000
M17 Gonarthrosis [arthrosis of knee]
0.691 0.309 0.000
J09-J18 Influenza and pneumonia
0.691 0.309 0.000
M49 Spondylopathies in diseases classified elsewhere
0.690 0.310 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.690 0.310 0.000
E06 Thyroiditis
0.690 0.310 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.690 0.310 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.690 0.310 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.690 0.310 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.690 0.310 0.000
I30 Acute pericarditis
0.690 0.310 0.000
M14 Arthropathies in other diseases classified elsewhere
0.689 0.311 0.000
M12 Other specific arthropathies
0.689 0.311 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.689 0.311 0.000
M08 Juvenile arthritis
0.689 0.311 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.687 0.313 0.000
M15 Polyarthrosis
0.685 0.315 0.000
L50-L54 Urticaria and erythema
0.683 0.317 0.000
R73 Elevated blood glucose level
0.683 0.317 0.000
Y40 Systemic antibiotics
0.682 0.318 0.000
L04 Acute lymphadenitis
0.681 0.319 0.000
L01 Impetigo
0.681 0.319 0.000
L00 Staphylococcal scalded skin syndrome
0.681 0.319 0.000
C67.2 Lateral wall of bladder
0.681 0.319 0.000
W19.3 Sports and athletics area
0.681 0.319 0.000
I46 Cardiac arrest
0.680 0.320 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.679 0.321 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.679 0.321 0.000
R04 Haemorrhage from respiratory passages
0.678 0.322 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.678 0.322 0.000
E03.8 Other specified hypothyroidism
0.678 0.322 0.000
E03.5 Myxoedema coma
0.678 0.322 0.000
E03.4 Atrophy of thyroid (acquired)
0.678 0.322 0.000
E03.3 Postinfectious hypothyroidism
0.678 0.322 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.678 0.322 0.000
E03.1 Congenital hypothyroidism without goitre
0.678 0.322 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.678 0.322 0.000
L08 Other local infections of skin and subcutaneous tissue
0.677 0.322 0.000
I34.0 Mitral (valve) insufficiency
0.677 0.323 0.000
L03.2 Cellulitis of face
0.677 0.323 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.676 0.323 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.676 0.323 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.676 0.323 0.000
T82.3 Mechanical complication of other vascular grafts
0.676 0.323 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.676 0.323 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.676 0.323 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.675 0.325 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.674 0.326 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.674 0.326 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.673 0.327 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.673 0.327 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.672 0.328 0.000
M45 Ankylosing spondylitis
0.672 0.328 0.000
R47.0 Dysphasia and aphasia
0.672 0.328 0.000
M19.8 Other specified arthrosis
0.671 0.328 0.000
M19.2 Other secondary arthrosis
0.671 0.328 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.670 0.330 0.000
T78.3 Angioneurotic oedema
0.669 0.331 0.000
L85 Other epidermal thickening
0.669 0.331 0.000
M77 Other enthesopathies
0.669 0.331 0.000
I77 Other disorders of arteries and arterioles
0.669 0.331 0.000
Z99.1 Dependence on respirator
0.669 0.331 0.000
L03.1 Cellulitis of other parts of limb
0.668 0.332 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.668 0.332 0.000
M47.1 Other spondylosis with myelopathy
0.665 0.335 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.665 0.335 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.664 0.336 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.664 0.336 0.000
I72 Other aneurysm
0.663 0.337 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.662 0.338 0.000
R07.1 Chest pain on breathing
0.662 0.338 0.000
M10 Gout
0.661 0.339 0.000
E83.5 Disorders of calcium metabolism
0.660 0.340 0.000
T31 Burns classified according to extent of body surface involved
0.660 0.340 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.660 0.340 0.000
R50-R69 General symptoms and signs
0.659 0.341 0.000
L89 Decubitus ulcer
0.658 0.342 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.658 0.342 0.000
T85.2 Mechanical complication of intraocular lens
0.658 0.342 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.657 0.342 0.000
L60-L75 Disorders of skin appendages
0.657 0.343 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.657 0.343 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.657 0.343 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.657 0.343 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.657 0.343 0.000
R01 Cardiac murmurs and other cardiac sounds
0.656 0.343 0.000
R20.2 Paraesthesia of skin
0.657 0.343 0.000
I47.2 Ventricular tachycardia
0.656 0.344 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.656 0.344 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.655 0.345 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.655 0.345 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.654 0.346 0.000
J43 Emphysema
0.654 0.346 0.000
T81.9 Unspecified complication of procedure
0.654 0.346 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.654 0.346 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.654 0.346 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.654 0.346 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.654 0.346 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.653 0.347 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.653 0.347 0.000
Z85.6 Personal history of leukaemia
0.653 0.347 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.653 0.347 0.000
M13.8 Other specified arthritis
0.653 0.347 0.000
M13.1 Monoarthritis, not elsewhere classified
0.653 0.347 0.000
M13.0 Polyarthritis, unspecified
0.653 0.347 0.000
Y95 Nosocomial condition
0.653 0.347 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.652 0.348 0.000
Z43.3 Attention to colostomy
0.651 0.349 0.000
M47.2 Other spondylosis with radiculopathy
0.650 0.350 0.000
Chapter VI Diseases of the nervous system
0.650 0.350 0.000
W13 Fall from, out of or through building or structure
0.649 0.351 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.648 0.352 0.000
R25.3 Fasciculation
0.646 0.354 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.646 0.354 0.000
J20-J22 Other acute lower respiratory infections
0.646 0.354 0.000
L03.9 Cellulitis, unspecified
0.646 0.354 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.645 0.355 0.000
M48 Other spondylopathies
0.644 0.356 0.000
M47.86 Other spondylosis (Lumbar region)
0.643 0.357 0.000
R27 Other lack of coordination
0.643 0.357 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.643 0.357 0.000
T78.2 Anaphylactic shock, unspecified
0.643 0.357 0.000
T78.4 Allergy, unspecified
0.642 0.358 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.642 0.358 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.642 0.358 0.000
L94 Other localised connective tissue disorders
0.642 0.358 0.000
L93 Lupus erythematosus
0.642 0.358 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.642 0.358 0.000
L87 Transepidermal elimination disorders
0.642 0.358 0.000
L88 Pyoderma gangrenosum
0.642 0.358 0.000
L86 Keratoderma in diseases classified elsewhere
0.642 0.358 0.000
L84 Corns and callosities
0.642 0.358 0.000
L83 Acanthosis nigricans
0.642 0.358 0.000
L80 Vitiligo
0.642 0.358 0.000
I33 Acute and subacute endocarditis
0.642 0.358 0.000
S40-S49 Injuries to the shoulder and upper arm
0.642 0.358 0.000
Y88 Sequelae of surgical and medical care as external cause
0.641 0.359 0.000
C15-C26 Malignant neoplasms of digestive organs
0.641 0.359 0.000
I52 Other heart disorders in diseases classified elsewhere
0.641 0.359 0.000
I48 Atrial fibrillation and flutter
0.641 0.359 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.641 0.359 0.000
I41 Myocarditis in diseases classified elsewhere
0.641 0.359 0.000
I40 Acute myocarditis
0.641 0.359 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.641 0.359 0.000
I37 Pulmonary valve disorders
0.641 0.359 0.000
I36 Nonrheumatic tricuspid valve disorders
0.641 0.359 0.000
I32 Pericarditis in diseases classified elsewhere
0.641 0.359 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.640 0.360 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.640 0.360 0.000
M47.84 Other spondylosis (Thoracic region)
0.640 0.360 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.640 0.360 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.640 0.360 0.000
Z94 Transplanted organ and tissue status
0.639 0.361 0.000
M40-M43 Deforming dorsopathies
0.639 0.361 0.000
R47.8 Other and unspecified speech disturbances
0.639 0.361 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.639 0.361 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.638 0.361 0.000
I70 Atherosclerosis
0.638 0.361 0.000
E83.3 Disorders of phosphorus metabolism
0.638 0.362 0.000
M54.9 Dorsalgia, unspecified
0.638 0.362 0.000
Z89.4 Acquired absence of foot and ankle
0.637 0.363 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.637 0.363 0.000
W07 Fall involving chair
0.636 0.364 0.000
R07.0 Pain in throat
0.635 0.365 0.000
H90-H95 Other disorders of ear
0.635 0.365 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.633 0.367 0.000
L03.8 Cellulitis of other sites
0.633 0.367 0.000
S72 Fracture of femur
0.633 0.367 0.000
T75 Effects of other external causes
0.632 0.368 0.000
T74 Maltreatment syndromes
0.632 0.368 0.000
T73 Effects of other deprivation
0.632 0.368 0.000
T70 Effects of air pressure and water pressure
0.632 0.368 0.000
T69 Other effects of reduced temperature
0.632 0.368 0.000
T67 Effects of heat and light
0.632 0.368 0.000
T71 Asphyxiation
0.632 0.368 0.000
T68 Hypothermia
0.632 0.368 0.000
T66 Unspecified effects of radiation
0.632 0.368 0.000
C67.6 Ureteric orifice
0.632 0.368 0.000
I10-I15 Hypertensive diseases
0.632 0.368 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.632 0.368 0.000
M66 Spontaneous rupture of synovium and tendon
0.632 0.368 0.000
R76 Other abnormal immunological findings in serum
0.632 0.368 0.000
E23 Hypofunction and other disorders of pituitary gland
0.631 0.369 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.631 0.369 0.000
E04 Other non-toxic goitre
0.631 0.369 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.630 0.370 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.629 0.370 0.000
Z98.1 Arthrodesis status
0.629 0.370 0.000
I71 Aortic aneurysm and dissection
0.629 0.371 0.000
S09 Other and unspecified injuries of head
0.629 0.371 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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