TreeWAS – Variant ID: rs2954038

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	1.000	0.000	0.000
E78.5 Hyperlipidaemia, unspecified	1.000	0.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.997	0.003	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.995	0.005	0.000
I25.2 Old myocardial infarction	0.980	0.020	0.000
E78.2 Mixed hyperlipidaemia	0.959	0.041	0.000
E78.1 Pure hyperglyceridaemia	0.906	0.094	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.872	0.128	0.000
I25.3 Aneurysm of heart	0.852	0.148	0.000
I25.4 Coronary artery aneurysm	0.831	0.169	0.000
I25.5 Ischaemic cardiomyopathy	0.792	0.208	0.000
E78.4 Other hyperlipidaemia	0.757	0.243	0.000
I25.6 Silent myocardial ischaemia	0.737	0.263	0.000
E78.3 Hyperchylomicronaemia	0.717	0.283	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.673	0.327	0.000
E78.6 Lipoprotein deficiency	0.637	0.363	0.000
E78.8 Other disorders of lipoprotein metabolism	0.629	0.371	0.000
I50.1 Left ventricular failure	0.450	0.550	0.000
I20-I25 Ischaemic heart diseases	0.377	0.623	0.000
I20 Angina pectoris	0.329	0.671	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.316	0.684	0.000
I21 Acute myocardial infarction	0.310	0.690	0.000
I20.9 Angina pectoris, unspecified	0.295	0.705	0.000
I20.8 Other forms of angina pectoris	0.266	0.734	0.000
I20.0 Unstable angina	0.264	0.736	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.222	0.778	0.000
I24 Other acute ischaemic heart diseases	0.210	0.790	0.000
I23 Certain current complications following acute myocardial infarction	0.206	0.793	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.200	0.800	0.000
I22 Subsequent myocardial infarction	0.196	0.804	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.188	0.812	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.173	0.827	0.000
I50 Heart failure	0.168	0.832	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.148	0.852	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.148	0.852	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.148	0.852	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.148	0.852	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.148	0.852	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.148	0.852	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.148	0.852	0.000
I50.0 Congestive heart failure	0.142	0.858	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.140	0.860	0.000
I24.1 Dressler's syndrome	0.139	0.861	0.000
I21.4 Acute subendocardial myocardial infarction	0.135	0.865	0.000
I20.1 Angina pectoris with documented spasm	0.134	0.865	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.124	0.876	0.000
E27 Other disorders of adrenal gland	0.118	0.882	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.115	0.885	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.108	0.892	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.106	0.893	0.001
E27.9 Disorder of adrenal gland, unspecified	0.102	0.898	0.000
E27.1 Primary adrenocortical insufficiency	0.101	0.899	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.097	0.903	0.000
I22.8 Subsequent myocardial infarction of other sites	0.094	0.906	0.000
E27.2 Addisonian crisis	0.090	0.910	0.000
E20-E35 Disorders of other endocrine glands	0.089	0.911	0.000
I23.8 Other current complications following acute myocardial infarction	0.084	0.915	0.001
E27.5 Adrenomedullary hyperfunction	0.085	0.915	0.000
E27.0 Other adrenocortical overactivity	0.085	0.915	0.000
E24 Cushing's syndrome	0.083	0.917	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.082	0.918	0.000
E28 Ovarian dysfunction	0.080	0.920	0.000
E23 Hypofunction and other disorders of pituitary gland	0.080	0.920	0.000
E27.8 Other specified disorders of adrenal gland	0.078	0.922	0.000
I21.9 Acute myocardial infarction, unspecified	0.077	0.923	0.000
E28.2 Polycystic ovarian syndrome	0.076	0.924	0.000
E24.9 Cushing's syndrome, unspecified	0.076	0.924	0.000
E23.2 Diabetes insipidus	0.071	0.929	0.000
E23.6 Other disorders of pituitary gland	0.070	0.930	0.000
E24.0 Pituitary-dependent Cushing's disease	0.070	0.930	0.000
Z95.1 Presence of aortocoronary bypass graft	0.068	0.932	0.000
I50.9 Heart failure, unspecified	0.064	0.936	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.064	0.936	0.000
E32 Diseases of thymus	0.064	0.936	0.000
E31 Polyglandular dysfunction	0.064	0.936	0.000
E30 Disorders of puberty, not elsewhere classified	0.064	0.936	0.000
E25 Adrenogenital disorders	0.063	0.937	0.000
E24.8 Other Cushing's syndrome	0.063	0.937	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.060	0.940	0.000
E24.3 Ectopic ACTH syndrome	0.060	0.940	0.000
E24.1 Nelson's syndrome	0.060	0.940	0.000
E20 Hypoparathyroidism	0.058	0.942	0.000
E28.9 Ovarian dysfunction, unspecified	0.058	0.942	0.000
E28.8 Other ovarian dysfunction	0.058	0.942	0.000
E28.1 Androgen excess	0.058	0.942	0.000
E28.0 Oestrogen excess	0.058	0.942	0.000
E23.7 Disorder of pituitary gland, unspecified	0.058	0.942	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.057	0.942	0.000
E23.1 Drug-induced hypopituitarism	0.057	0.942	0.000
I24.8 Other forms of acute ischaemic heart disease	0.056	0.944	0.000
E26 Hyperaldosteronism	0.055	0.945	0.000
E34 Other endocrine disorders	0.054	0.946	0.000
E24.2 Drug-induced Cushing's syndrome	0.053	0.947	0.000
E28.3 Primary ovarian failure	0.052	0.948	0.000
E29 Testicular dysfunction	0.049	0.950	0.000
E70-E90 Metabolic disorders	0.049	0.951	0.000
E22 Hyperfunction of pituitary gland	0.046	0.953	0.000
E30.9 Disorder of puberty, unspecified	0.046	0.954	0.000
E30.8 Other disorders of puberty	0.046	0.954	0.000
E30.1 Precocious puberty	0.046	0.954	0.000
E30.0 Delayed puberty	0.046	0.954	0.000
E31.9 Polyglandular dysfunction, unspecified	0.046	0.954	0.000
E31.8 Other polyglandular dysfunction	0.046	0.954	0.000
E31.1 Polyglandular hyperfunction	0.046	0.954	0.000
E31.0 Autoimmune polyglandular failure	0.046	0.954	0.000
E32.9 Disease of thymus, unspecified	0.046	0.954	0.000
E32.8 Other diseases of thymus	0.046	0.954	0.000
E32.1 Abscess of thymus	0.046	0.954	0.000
E32.0 Persistent hyperplasia of thymus	0.046	0.954	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.046	0.954	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.046	0.954	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.046	0.954	0.000
E25.9 Adrenogenital disorder, unspecified	0.045	0.955	0.000
E25.8 Other adrenogenital disorders	0.045	0.955	0.000
E34.0 Carcinoid syndrome	0.045	0.955	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.044	0.955	0.000
E23.0 Hypopituitarism	0.044	0.956	0.000
E26.9 Hyperaldosteronism, unspecified	0.043	0.957	0.000
E20.8 Other hypoparathyroidism	0.042	0.958	0.000
E20.1 Pseudohypoparathyroidism	0.042	0.958	0.000
E20.0 Idiopathic hypoparathyroidism	0.042	0.958	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.041	0.959	0.000
E26.8 Other hyperaldosteronism	0.040	0.960	0.000
E26.1 Secondary hyperaldosteronism	0.040	0.960	0.000
E34.5 Androgen resistance syndrome	0.039	0.961	0.000
E34.4 Constitutional tall stature	0.039	0.961	0.000
E34.3 Short stature, not elsewhere classified	0.039	0.961	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.039	0.961	0.000
E34.1 Other hypersecretion of intestinal hormones	0.039	0.961	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.039	0.961	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.038	0.962	0.000
E89.3 Postprocedural hypopituitarism	0.038	0.962	0.000
E84 Cystic fibrosis	0.037	0.963	0.000
E34.8 Other specified endocrine disorders	0.036	0.963	0.000
E20.9 Hypoparathyroidism, unspecified	0.036	0.964	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.036	0.964	0.000
E29.9 Testicular dysfunction, unspecified	0.036	0.964	0.000
E29.8 Other testicular dysfunction	0.036	0.964	0.000
E29.0 Testicular hyperfunction	0.036	0.964	0.000
E77 Disorders of glycoprotein metabolism	0.035	0.964	0.000
E76 Disorders of glycosaminoglycan metabolism	0.035	0.964	0.000
E74 Other disorders of carbohydrate metabolism	0.036	0.964	0.000
E72 Other disorders of amino-acid metabolism	0.035	0.964	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.035	0.964	0.000
E70 Disorders of aromatic amino-acid metabolism	0.035	0.964	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.035	0.964	0.000
E73 Lactose intolerance	0.035	0.965	0.000
E85 Amyloidosis	0.034	0.966	0.000
E22.8 Other hyperfunction of pituitary gland	0.033	0.966	0.000
E79 Disorders of purine and pyrimidine metabolism	0.033	0.966	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.033	0.967	0.000
E88 Other metabolic disorders	0.033	0.967	0.000
E89.4 Postprocedural ovarian failure	0.032	0.968	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.032	0.968	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.031	0.969	0.000
U89.8 Agent resistant to other single specified antibiotic	0.031	0.969	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.029	0.971	0.000
E84.9 Cystic fibrosis, unspecified	0.029	0.971	0.000
E85.9 Amyloidosis, unspecified	0.028	0.971	0.000
E21.2 Other hyperparathyroidism	0.028	0.972	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.028	0.972	0.000
E89.5 Postprocedural testicular hypofunction	0.028	0.972	0.000
E89.1 Postprocedural hypoinsulinaemia	0.028	0.972	0.000
U89 Agent resistant to other and unspecified antibiotics	0.028	0.972	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.027	0.973	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.027	0.973	0.000
E84.8 Cystic fibrosis with other manifestations	0.027	0.973	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.027	0.973	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.027	0.973	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.027	0.973	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.027	0.973	0.000
E40-E46 Malnutrition	0.027	0.973	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.026	0.973	0.000
E21.4 Other specified disorders of parathyroid gland	0.026	0.974	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.026	0.974	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.026	0.974	0.000
E70.3 Albinism	0.026	0.974	0.000
E70.2 Disorders of tyrosine metabolism	0.026	0.974	0.000
E70.1 Other hyperphenylalaninaemias	0.026	0.974	0.000
E70.0 Classical phenylketonuria	0.026	0.974	0.000
E71.3 Disorders of fatty-acid metabolism	0.026	0.974	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.026	0.974	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.026	0.974	0.000
E71.0 Maple-syrup-urine disease	0.026	0.974	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.026	0.974	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.026	0.974	0.000
E72.5 Disorders of glycine metabolism	0.026	0.974	0.000
E72.4 Disorders of ornithine metabolism	0.026	0.974	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.026	0.974	0.000
E72.2 Disorders of urea cycle metabolism	0.026	0.974	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.026	0.974	0.000
E72.0 Disorders of amino-acid transport	0.026	0.974	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.026	0.974	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.026	0.974	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.026	0.974	0.000
E76.2 Other mucopolysaccharidoses	0.026	0.974	0.000
E76.1 Mucopolysaccharidosis, type II	0.026	0.974	0.000
E76.0 Mucopolysaccharidosis, type I	0.026	0.974	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.026	0.974	0.000
E77.8 Other disorders of glycoprotein metabolism	0.026	0.974	0.000
E77.1 Defects in glycoprotein degradation	0.026	0.974	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.026	0.974	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.026	0.974	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.026	0.974	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.026	0.974	0.000
E74.2 Disorders of galactose metabolism	0.026	0.974	0.000
E74.1 Disorders of fructose metabolism	0.026	0.974	0.000
E74.0 Glycogen storage disease	0.026	0.974	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.026	0.974	0.000
U51 Admission status on psychiatric patients	0.026	0.974	0.000
E73.8 Other lactose intolerance	0.025	0.975	0.000
E73.1 Secondary lactase deficiency	0.025	0.975	0.000
E73.0 Congenital lactase deficiency	0.025	0.975	0.000
U80 Agent resistant to penicillin and related antibiotics	0.025	0.975	0.000
E88.8 Other specified metabolic disorders	0.025	0.975	0.000
E73.9 Lactose intolerance, unspecified	0.025	0.975	0.000
E85.8 Other amyloidosis	0.025	0.975	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.025	0.975	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.025	0.975	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.025	0.975	0.000
Chapter XXII Codes for special purposes	0.025	0.975	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.025	0.975	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.024	0.975	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.024	0.976	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.024	0.976	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.024	0.976	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.024	0.976	0.000
E79.1 Lesch-Nyhan syndrome	0.024	0.976	0.000
E26.0 Primary hyperaldosteronism	0.024	0.976	0.001
N85.4 Malposition of uterus	0.000	0.976	0.024
E16 Other disorders of pancreatic internal secretion	0.024	0.976	0.000
E75.6 Lipid storage disorder, unspecified	0.024	0.976	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.024	0.976	0.000
E75.3 Sphingolipidosis, unspecified	0.024	0.976	0.000
E75.2 Other sphingolipidosis	0.024	0.976	0.000
E75.1 Other gangliosidosis	0.024	0.976	0.000
E75.0 GM2 gangliosidosis	0.024	0.976	0.000
K76.6 Portal hypertension	0.024	0.976	0.000
E22.1 Hyperprolactinaemia	0.023	0.976	0.000
E22.0 Acromegaly and pituitary gigantism	0.023	0.976	0.000
E88.9 Metabolic disorder, unspecified	0.023	0.977	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.023	0.977	0.000
E15 Nondiabetic hypoglycaemic coma	0.023	0.977	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.022	0.978	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.022	0.978	0.000
K76 Other diseases of liver	0.022	0.978	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.022	0.978	0.000
E85.3 Secondary systemic amyloidosis	0.022	0.978	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.022	0.978	0.000
E88.3 Tumour lysis syndrome	0.021	0.978	0.000
U80.0 Penicillin resistant agent	0.022	0.978	0.000
U88 Agent resistant to multiple antibiotics	0.021	0.978	0.000
E75.5 Other lipid storage disorders	0.021	0.978	0.000
E29.1 Testicular hypofunction	0.021	0.979	0.000
E88.2 Lipomatosis, not elsewhere classified	0.021	0.979	0.000
E85.4 Organ-limited amyloidosis	0.021	0.979	0.000
E21.3 Hyperparathyroidism, unspecified	0.021	0.979	0.000
U89.9 Agent resistant to unspecified antibiotic	0.020	0.980	0.000
E34.9 Endocrine disorder, unspecified	0.019	0.980	0.001
U80.1 Methicillin resistant agent	0.020	0.980	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.020	0.980	0.000
U50 Level of care administered to neonates	0.019	0.980	0.000
U07 Emergency use of U07	0.019	0.980	0.000
U06 Emergency use of U06	0.019	0.980	0.000
U04 Severe acute respiratory syndrome [SARS]	0.019	0.980	0.000
U52 First in a series of a regular day/night admissions	0.019	0.980	0.000
E16.1 Other hypoglycaemia	0.019	0.980	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.019	0.981	0.000
E45 Retarded development following protein-energy malnutrition	0.019	0.981	0.000
E43 Unspecified severe protein-energy malnutrition	0.019	0.981	0.000
E42 Marasmic kwashiorkor	0.019	0.981	0.000
E41 Nutritional marasmus	0.019	0.981	0.000
E40 Kwashiorkor	0.019	0.981	0.000
E00-E07 Disorders of thyroid gland	0.019	0.981	0.000
U84 Resistance to other antimicrobial drugs	0.019	0.981	0.000
U83 Resistance to other antibiotics	0.019	0.981	0.000
U82 Resistance to betalactam antibiotics	0.019	0.981	0.000
U85 Resistance to antineoplastic drugs	0.019	0.981	0.000
U51.2 Previously admitted to a psychiatric hospital of another provider	0.019	0.981	0.000
K76.7 Hepatorenal syndrome	0.018	0.982	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.018	0.982	0.000
E80.5 Crigler-Najjar syndrome	0.018	0.982	0.000
E80.3 Defects of catalase and peroxydase	0.018	0.982	0.000
E80.0 Hereditary erythropoietic porphyria	0.018	0.982	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.017	0.982	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.017	0.982	0.000
E16.4 Abnormal secretion of gastrin	0.017	0.982	0.000
E16.3 Increased secretion of glucagon	0.017	0.982	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.017	0.983	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.017	0.983	0.000
E89.2 Postprocedural hypoparathyroidism	0.017	0.983	0.000
U81.0 Vancomycin resistant agent	0.017	0.983	0.000
K76.9 Liver disease, unspecified	0.017	0.983	0.000
E80.6 Other disorders of bilirubin metabolism	0.017	0.983	0.000
E80.2 Other porphyria	0.017	0.983	0.000
E80.1 Porphyria cutanea tarda	0.016	0.984	0.000
K76.5 Hepatic veno-occlusive disease	0.016	0.984	0.000
K76.4 Peliosis hepatis	0.016	0.984	0.000
K76.3 Infarction of liver	0.016	0.984	0.000
K76.2 Central haemorrhagic necrosis of liver	0.016	0.984	0.000
E46 Unspecified protein-energy malnutrition	0.016	0.984	0.000
E50-E64 Other nutritional deficiencies	0.016	0.984	0.000
E05.9 Thyrotoxicosis, unspecified	0.016	0.984	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.016	0.984	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.015	0.985	0.000
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.014	0.986	0.000
U06.9 Emergency use of U06.9	0.014	0.986	0.000
U06.8 Emergency use of U06.8	0.014	0.986	0.000
U06.7 Emergency use of U06.7	0.014	0.986	0.000
U06.6 Emergency use of U06.6	0.014	0.986	0.000
U06.5 Emergency use of U06.5	0.014	0.986	0.000
U06.4 Emergency use of U06.4	0.014	0.986	0.000
U06.3 Emergency use of U06.3	0.014	0.986	0.000
U06.2 Emergency use of U06.2	0.014	0.986	0.000
U06.1 Emergency use of U06.1	0.014	0.986	0.000
U06.0 Emergency use of U06.0	0.014	0.986	0.000
U07.9 Emergency use of U07.9	0.014	0.986	0.000
U07.8 Emergency use of U07.8	0.014	0.986	0.000
U07.7 Emergency use of U07.7	0.014	0.986	0.000
U07.6 Emergency use of U07.6	0.014	0.986	0.000
U07.5 Emergency use of U07.5	0.014	0.986	0.000
U07.4 Emergency use of U07.4	0.014	0.986	0.000
U07.3 Emergency use of U07.3	0.014	0.986	0.000
U07.2 Emergency use of U07.2	0.014	0.986	0.000
U07.1 Emergency use of U07.1	0.014	0.986	0.000
U07.0 Emergency use of U07.0	0.014	0.986	0.000
U50.9 Inquest Adjourned Death	0.014	0.986	0.000
U50.3 Level of care administered to neonates (Maximal Intensive Care)	0.014	0.986	0.000
U50.2 Level of care administered to neonates (High Dependancy Intensive Care)	0.014	0.986	0.000
U50.1 Level of care administered to neonates (Special Care)	0.014	0.986	0.000
U50.0 Level of care administered to neonates (Normal Care)	0.014	0.986	0.000
E44.1 Mild protein-energy malnutrition	0.014	0.986	0.000
E44.0 Moderate protein-energy malnutrition	0.014	0.986	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.014	0.986	0.000
E00 Congenital iodine-deficiency syndrome	0.014	0.986	0.000
K76.1 Chronic passive congestion of liver	0.014	0.986	0.000
U82.9 Resistance to betalactam antibiotics, unspecified	0.014	0.986	0.000
U82.8 Resistance to other betalactam antibiotics	0.014	0.986	0.000
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.014	0.986	0.000
U82.1 Resistance to methicillin	0.014	0.986	0.000
U82.0 Resistance to penicillin	0.014	0.986	0.000
U83.9 Resistance to unspecified antibiotic	0.014	0.986	0.000
U83.8 Resistance to other single specified antibiotic	0.014	0.986	0.000
U83.7 Resistance to multiple antibiotics	0.014	0.986	0.000
U83.2 Resistance to quinolones	0.014	0.986	0.000
U83.1 Resistance to other vancomycin related antibiotics	0.014	0.986	0.000
U83.0 Resistance to vancomycin	0.014	0.986	0.000
U84.9 Resistance to unspecified antimicrobial drugs	0.014	0.986	0.000
U84.8 Resistance to other specified antimicrobial drug	0.014	0.986	0.000
U84.7 Resistance to multiple antimicrobial drugs	0.014	0.986	0.000
U84.3 Resistance to tuberculostatic drug(s)	0.014	0.986	0.000
U84.2 Resistance to antiviral drug(s)	0.014	0.986	0.000
U84.1 Resistance to antifungal drug(s)	0.014	0.986	0.000
U84.0 Resistance to antiparasitic drug(s)	0.014	0.986	0.000
E06 Thyroiditis	0.013	0.987	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.013	0.987	0.000
E80.4 Gilbert's syndrome	0.013	0.987	0.000
E05.8 Other thyrotoxicosis	0.013	0.987	0.000
E05.5 Thyroid crisis or storm	0.013	0.987	0.000
E05.4 Thyrotoxicosis factitia	0.013	0.987	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.013	0.987	0.000
E07 Other disorders of thyroid	0.012	0.988	0.000
E58 Dietary calcium deficiency	0.012	0.988	0.000
E06.9 Thyroiditis, unspecified	0.012	0.988	0.000
E65-E68 Obesity and other hyperalimentation	0.012	0.988	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.011	0.988	0.000
E63 Other nutritional deficiencies	0.011	0.988	0.000
E50 Vitamin A deficiency	0.011	0.988	0.000
E60 Dietary zinc deficiency	0.011	0.988	0.000
E59 Dietary selenium deficiency	0.011	0.988	0.000
E54 Ascorbic acid deficiency	0.011	0.988	0.000
E52 Niacin deficiency [pellagra]	0.011	0.988	0.000
E61 Deficiency of other nutrient elements	0.011	0.989	0.000
E10.3 With ophthalmic complications	0.000	0.989	0.011
E56 Other vitamin deficiencies	0.011	0.989	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.011	0.989	0.000
E51 Thiamine deficiency	0.011	0.989	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.010	0.990	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.010	0.990	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.010	0.990	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.010	0.990	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.010	0.990	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.010	0.990	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.010	0.990	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.010	0.990	0.000
E06.5 Other chronic thyroiditis	0.010	0.990	0.000
E06.4 Drug-induced thyroiditis	0.010	0.990	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.010	0.990	0.000
E06.1 Subacute thyroiditis	0.010	0.990	0.000
E06.0 Acute thyroiditis	0.010	0.990	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.990	0.010
E07.9 Disorder of thyroid, unspecified	0.009	0.991	0.000
E07.1 Dyshormogenetic goitre	0.009	0.991	0.000
E07.0 Hypersecretion of calcitonin	0.009	0.991	0.000
E61.2 Magnesium deficiency	0.009	0.991	0.000
E89.0 Postprocedural hypothyroidism	0.009	0.991	0.000
E10.4 With neurological complications	0.000	0.991	0.009
E10 Insulin-dependent diabetes mellitus	0.000	0.991	0.009
E67 Other hyperalimentation	0.008	0.991	0.000
E68 Sequelae of hyperalimentation	0.008	0.991	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.008	0.991	0.000
E50.9 Vitamin A deficiency, unspecified	0.008	0.991	0.000
E50.8 Other manifestations of vitamin A deficiency	0.008	0.991	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.008	0.991	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.008	0.991	0.000
E50.5 Vitamin A deficiency with night blindness	0.008	0.991	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.008	0.991	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.008	0.991	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.008	0.991	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.008	0.991	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.008	0.991	0.000
E63.9 Nutritional deficiency, unspecified	0.008	0.991	0.000
E63.8 Other specified nutritional deficiencies	0.008	0.991	0.000
E63.1 Imbalance of constituents of food intake	0.008	0.991	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.008	0.991	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.008	0.991	0.000
E64.8 Sequelae of other nutritional deficiencies	0.008	0.991	0.000
E64.3 Sequelae of rickets	0.008	0.991	0.000
E64.2 Sequelae of vitamin C deficiency	0.008	0.991	0.000
E64.1 Sequelae of vitamin A deficiency	0.008	0.991	0.000
E64.0 Sequelae of protein-energy malnutrition	0.008	0.991	0.000
E03 Other hypothyroidism	0.009	0.991	0.000
K76.8 Other specified diseases of liver	0.008	0.992	0.000
E61.9 Deficiency of nutrient element, unspecified	0.008	0.992	0.000
E61.8 Deficiency of other specified nutrient elements	0.008	0.992	0.000
E61.7 Deficiency of multiple nutrient elements	0.008	0.992	0.000
E61.6 Vanadium deficiency	0.008	0.992	0.000
E61.5 Molybdenum deficiency	0.008	0.992	0.000
E61.4 Chromium deficiency	0.008	0.992	0.000
E61.3 Manganese deficiency	0.008	0.992	0.000
E61.0 Copper deficiency	0.008	0.992	0.000
E56.9 Vitamin deficiency, unspecified	0.008	0.992	0.000
E56.8 Deficiency of other vitamins	0.008	0.992	0.000
E56.0 Deficiency of vitamin E	0.008	0.992	0.000
E55 Vitamin D deficiency	0.008	0.992	0.000
E51.9 Thiamine deficiency, unspecified	0.008	0.992	0.000
E51.8 Other manifestations of thiamine deficiency	0.008	0.992	0.000
E51.1 Beriberi	0.008	0.992	0.000
E10.2 With renal complications	0.000	0.992	0.008
E56.1 Deficiency of vitamin K	0.008	0.992	0.000
I73.9 Peripheral vascular disease, unspecified	0.008	0.992	0.000
E61.1 Iron deficiency	0.008	0.992	0.000
D69.6 Thrombocytopenia, unspecified	0.008	0.992	0.000
E10.6 With other specified complications	0.000	0.992	0.007
H60.9 Otitis externa, unspecified	0.000	0.993	0.007
E51.2 Wernicke's encephalopathy	0.007	0.993	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.007	0.993	0.000
E10.5 With peripheral circulatory complications	0.000	0.993	0.007
E10.7 With multiple complications	0.000	0.993	0.006
E10.0 With coma	0.000	0.993	0.006
E07.8 Other specified disorders of thyroid	0.006	0.993	0.000
E67.8 Other specified hyperalimentation	0.006	0.993	0.000
E67.3 Hypervitaminosis D	0.006	0.993	0.000
E67.2 Megavitamin-B6 syndrome	0.006	0.993	0.000
E67.1 Hypercarotenaemia	0.006	0.993	0.000
E67.0 Hypervitaminosis A	0.006	0.993	0.000
E03.5 Myxoedema coma	0.006	0.994	0.000
E03.4 Atrophy of thyroid (acquired)	0.006	0.994	0.000
E03.3 Postinfectious hypothyroidism	0.006	0.994	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.006	0.994	0.000
E03.1 Congenital hypothyroidism without goitre	0.006	0.994	0.000
E55.0 Rickets, active	0.006	0.994	0.000
E10.8 With unspecified complications	0.000	0.994	0.006
I73 Other peripheral vascular diseases	0.006	0.994	0.000
E53 Deficiency of other B group vitamins	0.006	0.994	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.994	0.006
I73.8 Other specified peripheral vascular diseases	0.006	0.994	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.006	0.994	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.994	0.006
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.994	0.006
E03.8 Other specified hypothyroidism	0.006	0.994	0.000
D69 Purpura and other haemorrhagic conditions	0.006	0.994	0.000
E65 Localised adiposity	0.005	0.995	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.005	0.995	0.000
D69.5 Secondary thrombocytopenia	0.005	0.995	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.005	0.995	0.000
M54.57 Low back pain (Lumbosacral region)	0.000	0.995	0.005
B91 Sequelae of poliomyelitis	0.000	0.995	0.005
I78 Diseases of capillaries	0.005	0.995	0.000
D69.1 Qualitative platelet defects	0.005	0.995	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.005	0.995	0.000
D69.8 Other specified haemorrhagic conditions	0.005	0.995	0.000
H60 Otitis externa	0.000	0.995	0.005
E53.1 Pyridoxine deficiency	0.004	0.995	0.000
E53.0 Riboflavin deficiency	0.004	0.995	0.000
E06.3 Autoimmune thyroiditis	0.004	0.995	0.000
I78.1 Naevus, nonneoplastic	0.005	0.995	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.004	0.996	0.000
D69.4 Other primary thrombocytopenia	0.004	0.996	0.000
I72 Other aneurysm	0.004	0.996	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.004	0.996	0.000
E10.1 With ketoacidosis	0.000	0.996	0.004
I72.3 Aneurysm of iliac artery	0.004	0.996	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.004	0.996	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.004	0.996	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.004	0.996	0.000
E21.0 Primary hyperparathyroidism	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations