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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7528419
log Bayes Factor = 124.033
Chromosome 1   position 109,817,192  (GRCh37) Explore rs7528419 on Ensembl!
Variant rs7528419 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.5 Hyperlipidaemia, unspecified
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.000 1.000
I20.0 Unstable angina
0.000 0.001 0.999
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.001 0.999
Z95.0 Presence of cardiac pacemaker
0.000 0.027 0.973
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.034 0.966
I21.4 Acute subendocardial myocardial infarction
0.000 0.044 0.956
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.078 0.922
E78.8 Other disorders of lipoprotein metabolism
0.000 0.079 0.921
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.082 0.918
I24 Other acute ischaemic heart diseases
0.000 0.101 0.899
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.104 0.896
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.111 0.889
I71 Aortic aneurysm and dissection
0.000 0.113 0.887
I25.3 Aneurysm of heart
0.000 0.116 0.884
I73 Other peripheral vascular diseases
0.000 0.117 0.883
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.118 0.882
I73.9 Peripheral vascular disease, unspecified
0.000 0.118 0.882
I74 Arterial embolism and thrombosis
0.000 0.154 0.846
Chapter IX Diseases of the circulatory system
0.000 0.156 0.844
E78.4 Other hyperlipidaemia
0.000 0.167 0.833
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.176 0.824
I24.8 Other forms of acute ischaemic heart disease
0.000 0.183 0.817
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.200 0.800
E78.2 Mixed hyperlipidaemia
0.000 0.203 0.797
I25.5 Ischaemic cardiomyopathy
0.000 0.207 0.793
E78.6 Lipoprotein deficiency
0.000 0.213 0.787
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.217 0.783
I25.4 Coronary artery aneurysm
0.000 0.219 0.781
I22 Subsequent myocardial infarction
0.000 0.222 0.778
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.272 0.728
I23 Certain current complications following acute myocardial infarction
0.000 0.274 0.726
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.281 0.719
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
I20.8 Other forms of angina pectoris
0.000 0.286 0.714
E78.1 Pure hyperglyceridaemia
0.000 0.286 0.714
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.298 0.702
I70 Atherosclerosis
0.000 0.303 0.697
I72 Other aneurysm
0.000 0.346 0.654
I74.8 Embolism and thrombosis of other arteries
0.000 0.354 0.646
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.355 0.645
Z95.2 Presence of prosthetic heart valve
0.000 0.356 0.644
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.357 0.643
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.364 0.636
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.364 0.636
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.364 0.636
I20.1 Angina pectoris with documented spasm
0.000 0.373 0.627
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.375 0.625
I73.8 Other specified peripheral vascular diseases
0.000 0.380 0.620
I00-I02 Acute rheumatic fever
0.000 0.390 0.610
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.393 0.607
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.402 0.597
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.403 0.597
I77 Other disorders of arteries and arterioles
0.000 0.403 0.597
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.419 0.581
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.422 0.578
I22.8 Subsequent myocardial infarction of other sites
0.000 0.423 0.577
I24.1 Dressler's syndrome
0.000 0.426 0.574
I72.4 Aneurysm of artery of lower extremity
0.000 0.428 0.572
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.439 0.561
I79.1 Aortitis in diseases classified elsewhere
0.000 0.439 0.561
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.439 0.561
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.443 0.557
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.464 0.536
I72.3 Aneurysm of iliac artery
0.000 0.469 0.531
I23.8 Other current complications following acute myocardial infarction
0.000 0.470 0.530
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.472 0.528
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.479 0.521
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.479 0.521
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.479 0.521
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.479 0.521
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.479 0.521
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.479 0.521
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.479 0.521
I10-I15 Hypertensive diseases
0.000 0.493 0.507
I70.8 Atherosclerosis of other arteries
0.000 0.498 0.502
I70.1 Atherosclerosis of renal artery
0.000 0.499 0.501
I70.9 Generalised and unspecified atherosclerosis
0.000 0.500 0.500
I71.0 Dissection of aorta [any part]
0.000 0.502 0.498
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.502 0.497
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.508 0.492
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.513 0.487
I72.2 Aneurysm of renal artery
0.000 0.518 0.482
I77.1 Stricture of artery
0.000 0.524 0.476
I78 Diseases of capillaries
0.000 0.529 0.471
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.531 0.469
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.531 0.469
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.534 0.466
I21.3 Acute transmural myocardial infarction of unspecified site
0.001 0.537 0.463
I77.6 Arteritis, unspecified
0.000 0.541 0.459
I70.0 Atherosclerosis of aorta
0.000 0.545 0.455
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.546 0.454
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.547 0.452
I00 Rheumatic fever without mention of heart involvement
0.000 0.558 0.442
I50 Heart failure
0.000 0.558 0.442
I15 Secondary hypertension
0.000 0.560 0.440
I02 Rheumatic chorea
0.000 0.563 0.437
I01 Rheumatic fever with heart involvement
0.000 0.563 0.437
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.563 0.437
I77.2 Rupture of artery
0.000 0.564 0.436
I30-I52 Other forms of heart disease
0.000 0.565 0.435
I72.8 Aneurysm of other specified arteries
0.000 0.568 0.432
I50.1 Left ventricular failure
0.000 0.569 0.431
I77.5 Necrosis of artery
0.000 0.572 0.428
I77.4 Coeliac artery compression syndrome
0.000 0.572 0.428
I77.3 Arterial fibromuscular dysplasia
0.000 0.572 0.428
I50.0 Congestive heart failure
0.000 0.576 0.424
I74.5 Embolism and thrombosis of iliac artery
0.000 0.584 0.416
I35.0 Aortic (valve) stenosis
0.000 0.588 0.412
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.588 0.412
I72.1 Aneurysm of artery of upper extremity
0.000 0.591 0.409
I35 Nonrheumatic aortic valve disorders
0.000 0.592 0.408
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.592 0.407
I72.9 Aneurysm of unspecified site
0.000 0.593 0.407
I11 Hypertensive heart disease
0.000 0.595 0.405
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.606 0.394
I45 Other conduction disorders
0.000 0.623 0.377
I45.1 Other and unspecified right bundle-branch block
0.000 0.625 0.375
I46 Cardiac arrest
0.000 0.626 0.374
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.627 0.373
I15.1 Hypertension secondary to other renal disorders
0.000 0.631 0.369
I13 Hypertensive heart and renal disease
0.000 0.636 0.363
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.637 0.363
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.640 0.360
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.640 0.360
I72.0 Aneurysm of carotid artery
0.000 0.640 0.360
I77.8 Other specified disorders of arteries and arterioles
0.000 0.640 0.360
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.641 0.359
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.641 0.358
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.641 0.358
I15.9 Seconday hypertension, unspecified
0.000 0.643 0.357
I50.9 Heart failure, unspecified
0.000 0.647 0.353
I77.0 Arteriovenous fistula, acquired
0.000 0.654 0.346
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.655 0.345
I46.0 Cardiac arrest with successful resuscitation
0.000 0.657 0.343
I78.9 Disease of capillaries, unspecified
0.000 0.662 0.338
I28 Other diseases of pulmonary vessels
0.000 0.664 0.336
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.669 0.330
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.000 0.670 0.330
I78.8 Other diseases of capillaries
0.000 0.671 0.329
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.673 0.326
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.674 0.326
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.677 0.323
Z95.3 Presence of xenogenic heart valve
0.001 0.680 0.320
I15.8 Other secondary hypertension
0.000 0.684 0.316
I15.2 Hypertension secondary to endocrine disorders
0.000 0.684 0.316
I15.0 Renovascular hypertension
0.000 0.684 0.316
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.686 0.314
I01.8 Other acute rheumatic heart disease
0.000 0.686 0.314
I01.2 Acute rheumatic myocarditis
0.000 0.686 0.314
I01.1 Acute rheumatic endocarditis
0.000 0.686 0.314
I01.0 Acute rheumatic pericarditis
0.000 0.686 0.314
I02.9 Rheumatic chorea without heart involvement
0.000 0.686 0.314
I02.0 Rheumatic chorea with heart involvement
0.000 0.686 0.314
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.687 0.313
Z82.2 Family history of deafness and hearing loss
0.000 0.687 0.313
I40 Acute myocarditis
0.000 0.687 0.313
I52 Other heart disorders in diseases classified elsewhere
0.000 0.688 0.312
I48 Atrial fibrillation and flutter
0.000 0.688 0.312
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.688 0.312
I41 Myocarditis in diseases classified elsewhere
0.000 0.688 0.312
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.688 0.312
I32 Pericarditis in diseases classified elsewhere
0.000 0.688 0.312
I99 Other and unspecified disorders of circulatory system
0.000 0.689 0.311
I33 Acute and subacute endocarditis
0.000 0.700 0.300
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.707 0.293
I45.2 Bifascicular block
0.000 0.709 0.291
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.713 0.287
I34 Nonrheumatic mitral valve disorders
0.000 0.714 0.286
I05-I09 Chronic rheumatic heart diseases
0.000 0.715 0.285
I28.8 Other specified diseases of pulmonary vessels
0.000 0.715 0.284
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.718 0.282
Z82.1 Family history of blindness and visual loss
0.000 0.720 0.280
I35.8 Other aortic valve disorders
0.000 0.722 0.278
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.728 0.272
I45.0 Right fascicular block
0.000 0.729 0.271
I46.1 Sudden cardiac death, so described
0.000 0.732 0.268
I34.1 Mitral (valve) prolapse
0.000 0.734 0.266
I45.5 Other specified heart block
0.000 0.734 0.266
I42 Cardiomyopathy
0.000 0.736 0.264
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.739 0.261
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.739 0.261
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.739 0.261
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.739 0.261
O34.2 Maternal care due to uterine scar from previous surgery
0.249 0.751 0.000
I45.3 Trifascicular block
0.000 0.751 0.249
I30 Acute pericarditis
0.000 0.754 0.245
I37 Pulmonary valve disorders
0.000 0.758 0.242
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.759 0.241
I28.1 Aneurysm of pulmonary artery
0.000 0.759 0.241
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.759 0.241
I35.9 Aortic valve disorder, unspecified
0.000 0.761 0.239
I38 Endocarditis, valve unspecified
0.000 0.763 0.237
I33.0 Acute and subacute infective endocarditis
0.000 0.771 0.229
I46.9 Cardiac arrest, unspecified
0.000 0.774 0.226
I45.9 Conduction disorder, unspecified
0.000 0.775 0.225
I40.0 Infective myocarditis
0.000 0.775 0.225
I40.9 Acute myocarditis, unspecified
0.000 0.775 0.224
I40.8 Other acute myocarditis
0.000 0.775 0.224
I40.1 Isolated myocarditis
0.000 0.775 0.224
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.776 0.224
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.776 0.224
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.776 0.224
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.776 0.224
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.776 0.224
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.776 0.224
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.776 0.224
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.776 0.224
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.776 0.224
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.776 0.224
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.776 0.224
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.776 0.224
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.776 0.224
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.776 0.224
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.776 0.224
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.776 0.224
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.776 0.224
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.776 0.224
I48.4 Atypical atrial flutter
0.000 0.776 0.224
I48.3 Typical atrial flutter
0.000 0.776 0.224
I48.2 Chronic atrial fibrillation
0.000 0.776 0.224
I48.1 Persistent atrial fibrillation
0.000 0.776 0.224
I48.0 Paroxysmal atrial fibrillation
0.000 0.776 0.224
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.776 0.224
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.776 0.224
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.776 0.224
I42.8 Other cardiomyopathies
0.000 0.779 0.221
I36 Nonrheumatic tricuspid valve disorders
0.001 0.781 0.218
I73.0 Raynaud's syndrome
0.000 0.783 0.217
I09 Other rheumatic heart diseases
0.000 0.787 0.213
I97.1 Other functional disturbances following cardiac surgery
0.000 0.787 0.213
I42.2 Other hypertrophic cardiomyopathy
0.000 0.789 0.211
I10 Essential (primary) hypertension
0.000 0.791 0.209
I78.1 Naevus, nonneoplastic
0.000 0.791 0.209
I45.8 Other specified conduction disorders
0.000 0.794 0.206
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.797 0.203
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.801 0.199
I06 Rheumatic aortic valve diseases
0.000 0.801 0.199
I45.4 Nonspecific intraventricular block
0.000 0.803 0.197
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.805 0.195
I97.0 Postcardiotomy syndrome
0.000 0.805 0.195
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.810 0.190
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.811 0.189
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.811 0.189
I42.5 Other restrictive cardiomyopathy
0.000 0.811 0.189
I42.4 Endocardial fibroelastosis
0.000 0.811 0.189
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.811 0.189
I33.9 Acute endocarditis, unspecified
0.000 0.815 0.185
I07 Rheumatic tricuspid valve diseases
0.000 0.815 0.185
I42.6 Alcoholic cardiomyopathy
0.000 0.817 0.183
S00.8 Superficial injury of other parts of head
0.000 0.821 0.179
I95 Hypotension
0.000 0.821 0.179
I27 Other pulmonary heart diseases
0.000 0.822 0.178
I30.8 Other forms of acute pericarditis
0.000 0.824 0.176
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.824 0.176
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.825 0.175
I37.9 Pulmonary valve disorder, unspecified
0.000 0.826 0.173
I37.8 Other pulmonary valve disorders
0.000 0.826 0.173
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.826 0.173
I37.0 Pulmonary valve stenosis
0.000 0.826 0.173
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.832 0.168
I05 Rheumatic mitral valve diseases
0.000 0.838 0.162
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.838 0.162
I09.9 Rheumatic heart disease, unspecified
0.000 0.838 0.162
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.001 0.843 0.157
I36.8 Other nonrheumatic tricuspid valve disorders
0.001 0.843 0.157
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.001 0.843 0.157
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.001 0.843 0.157
I26 Pulmonary embolism
0.002 0.843 0.155
I45.6 Preexcitation syndrome
0.000 0.844 0.156
I12 Hypertensive renal disease
0.000 0.844 0.155
I09.8 Other specified rheumatic heart diseases
0.000 0.847 0.153
I09.2 Chronic rheumatic pericarditis
0.000 0.847 0.153
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.847 0.153
I09.0 Rheumatic myocarditis
0.000 0.847 0.153
I30.1 Infective pericarditis
0.000 0.848 0.152
I34.0 Mitral (valve) insufficiency
0.000 0.848 0.152
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.850 0.150
S00 Superficial injury of head
0.000 0.851 0.149
I30.9 Acute pericarditis, unspecified
0.000 0.856 0.144
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.857 0.143
I06.8 Other rheumatic aortic valve diseases
0.000 0.857 0.143
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.857 0.143
I06.0 Rheumatic aortic stenosis
0.000 0.857 0.143
Z82.3 Family history of stroke
0.000 0.858 0.142
I95.9 Hypotension, unspecified
0.000 0.858 0.142
O34 Maternal care for known or suspected abnormality of pelvic organs
0.140 0.860 0.000
I27.9 Pulmonary heart disease, unspecified
0.000 0.862 0.138
I42.9 Cardiomyopathy, unspecified
0.000 0.862 0.138
I06.1 Rheumatic aortic insufficiency
0.000 0.863 0.137
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.863 0.136
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.863 0.136
I98.0 Cardiovascular syphilis
0.000 0.863 0.136
S00.0 Superficial injury of scalp
0.000 0.864 0.136
I05.2 Mitral stenosis with insufficiency
0.000 0.867 0.133
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.867 0.133
I07.9 Tricuspid valve disease, unspecified
0.000 0.867 0.133
I07.8 Other tricuspid valve diseases
0.000 0.867 0.133
I07.2 Tricuspid stenosis with insufficiency
0.000 0.867 0.133
I07.0 Tricuspid stenosis
0.000 0.867 0.133
I27.8 Other specified pulmonary heart diseases
0.000 0.867 0.133
S00.7 Multiple superficial injuries of head
0.000 0.867 0.133
I27.1 Kyphoscoliotic heart disease
0.000 0.872 0.128
I95.1 Orthostatic hypotension
0.000 0.875 0.125
I31 Other diseases of pericardium
0.000 0.876 0.124
I05.8 Other mitral valve diseases
0.000 0.883 0.116
O34.0 Maternal care for congenital malformation of uterus
0.116 0.884 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.115 0.885 0.000
I07.1 Tricuspid insufficiency
0.000 0.887 0.113
I05.1 Rheumatic mitral insufficiency
0.000 0.887 0.113
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.888 0.112
S00.1 Contusion of eyelid and periocular area
0.000 0.893 0.107
S00.5 Superficial injury of lip and oral cavity
0.000 0.894 0.106
I05.0 Mitral stenosis
0.000 0.895 0.105
S00.3 Superficial injury of nose
0.000 0.895 0.105
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.002 0.895 0.103
I95.2 Hypotension due to drugs
0.000 0.896 0.104
I37.1 Pulmonary valve insufficiency
0.001 0.897 0.102
O34.1 Maternal care for tumour of corpus uteri
0.103 0.897 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.101 0.899 0.000
O34.6 Maternal care for abnormality of vagina
0.101 0.899 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.101 0.899 0.000
O34.3 Maternal care for cervical incompetence
0.098 0.901 0.000
O34.4 Maternal care for other abnormalities of cervix
0.098 0.902 0.000
I42.0 Dilated cardiomyopathy
0.000 0.904 0.096
I95.0 Idiopathic hypotension
0.000 0.904 0.096
I95.8 Other hypotension
0.000 0.904 0.095
Z95.4 Presence of other heart-valve replacement
0.000 0.908 0.091
S00.4 Superficial injury of ear
0.000 0.909 0.091
O34.7 Maternal care for abnormality of vulva and perineum
0.091 0.909 0.000
I31.8 Other specified diseases of pericardium
0.000 0.911 0.089
I31.2 Haemopericardium, not elsewhere classified
0.000 0.911 0.089
I51 Complications and ill-defined descriptions of heart disease
0.000 0.916 0.084
S00.9 Superficial injury of head, part unspecified
0.000 0.918 0.082
I12.9 Hypertensive renal disease without renal failure
0.000 0.923 0.077
I27.0 Primary pulmonary hypertension
0.000 0.924 0.076
I31.0 Chronic adhesive pericarditis
0.000 0.925 0.075
I31.1 Chronic constrictive pericarditis
0.000 0.927 0.073
I31.3 Pericardial effusion (noninflammatory)
0.000 0.931 0.069
I51.0 Cardiac septal defect, acquired
0.000 0.934 0.066
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.002 0.936 0.063
I27.2 Other secondary pulmonary hypertension
0.000 0.936 0.064
I08 Multiple valve diseases
0.000 0.937 0.063
K05.3 Chronic periodontitis
0.062 0.938 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.939 0.061
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.939 0.061
I05.9 Mitral valve disease, unspecified
0.000 0.940 0.059
I51.9 Heart disease, unspecified
0.000 0.941 0.059
S00-S09 Injuries to the head
0.000 0.942 0.058
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.944 0.056
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.946 0.054
I51.8 Other ill-defined heart diseases
0.000 0.946 0.054
I98.2 Oesophageal varices in diseases classified elsewhere
0.001 0.946 0.053
I51.6 Cardiovascular disease, unspecified
0.000 0.946 0.053
I31.9 Disease of pericardium, unspecified
0.000 0.947 0.053
I51.5 Myocardial degeneration
0.000 0.948 0.052
S02 Fracture of skull and facial bones
0.000 0.950 0.050
S02.0 Fracture of vault of skull
0.000 0.952 0.048
I35.1 Aortic (valve) insufficiency
0.000 0.952 0.047
S02.00 Fracture of vault of skull (closed)
0.000 0.953 0.047
I49 Other cardiac arrhythmias
0.000 0.953 0.047
I47 Paroxysmal tachycardia
0.000 0.954 0.046
S02.2 Fracture of nasal bones
0.000 0.955 0.045
S09 Other and unspecified injuries of head
0.000 0.955 0.045
S01 Open wound of head
0.000 0.955 0.045
S01.9 Open wound of head, part unspecified
0.000 0.956 0.044
S08 Traumatic amputation of part of head
0.000 0.958 0.042
S07 Crushing injury of head
0.000 0.958 0.042
S04 Injury of cranial nerves
0.000 0.958 0.042
S02.20 Fracture of nasal bones (closed)
0.000 0.958 0.042
I08.9 Multiple valve disease, unspecified
0.000 0.958 0.041
S01.7 Multiple open wounds of head
0.000 0.959 0.041
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.960 0.040
S03 Dislocation, sprain and strain of joints and ligaments of head
0.000 0.960 0.040
S05 Injury of eye and orbit
0.000 0.961 0.039
I49.5 Sick sinus syndrome
0.000 0.961 0.039
S02.7 Multiple fractures involving skull and facial bones
0.000 0.961 0.039
S09.8 Other specified injuries of head
0.000 0.961 0.039
S02.8 Fractures of other skull and facial bones
0.000 0.963 0.036
I51.7 Cardiomegaly
0.000 0.964 0.036
I49.1 Atrial premature depolarisation
0.000 0.964 0.036
K05 Gingivitis and periodontal diseases
0.036 0.964 0.000
I08.8 Other multiple valve diseases
0.000 0.964 0.036
S01.1 Open wound of eyelid and periocular area
0.000 0.964 0.036
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.964 0.036
S02.01 Fracture of vault of skull (open)
0.000 0.965 0.035
S02.6 Fracture of mandible
0.000 0.966 0.034
I49.2 Junctional premature depolarisation
0.000 0.966 0.034
I60-I69 Cerebrovascular diseases
0.000 0.967 0.033
S01.3 Open wound of ear
0.000 0.967 0.033
S02.21 Fracture of nasal bones (open)
0.000 0.967 0.032
S09.7 Multiple injuries of head
0.000 0.967 0.032
S09.2 Traumatic rupture of ear drum
0.000 0.967 0.032
S09.1 Injury of muscle and tendon of head
0.000 0.967 0.032
S09.0 Injury of blood vessels of head, not elsewhere classified
0.000 0.968 0.031
K05.6 Periodontal disease, unspecified
0.031 0.969 0.000
S05.8 Other injuries of eye and orbit
0.000 0.969 0.031
S03.2 Dislocation of tooth
0.000 0.969 0.031
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.969 0.031
S02.3 Fracture of orbital floor
0.000 0.970 0.030
I49.8 Other specified cardiac arrhythmias
0.000 0.970 0.030
S04.9 Injury of unspecified cranial nerve
0.000 0.970 0.030
S04.8 Injury of other cranial nerves
0.000 0.970 0.030
S04.7 Injury of accessory nerve
0.000 0.970 0.030
S04.6 Injury of acoustic nerve
0.000 0.970 0.030
S04.5 Injury of facial nerve
0.000 0.970 0.030
S04.4 Injury of abducent nerve
0.000 0.970 0.030
S04.3 Injury of trigeminal nerve
0.000 0.970 0.030
S04.2 Injury of trochlear nerve
0.000 0.970 0.030
S04.1 Injury of oculomotor nerve
0.000 0.970 0.030
S04.0 Injury of optic nerve and pathways
0.000 0.970 0.030
S07.9 Crushing injury of head, part unspecified
0.000 0.970 0.030
S07.8 Crushing injury of other parts of head
0.000 0.970 0.030
S07.1 Crushing injury of skull
0.000 0.970 0.030
S07.0 Crushing injury of face
0.000 0.970 0.030
S08.9 Traumatic amputation of unspecified part of head
0.000 0.970 0.030
S08.8 Traumatic amputation of other parts of head
0.000 0.970 0.030
S08.1 Traumatic amputation of ear
0.000 0.970 0.030
S08.0 Avulsion of scalp
0.000 0.970 0.030
S05.1 Contusion of eyeball and orbital tissues
0.000 0.970 0.030
S01.2 Open wound of nose
0.000 0.970 0.030
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.971 0.029
I69 Sequelae of cerebrovascular disease
0.000 0.971 0.029
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head
0.000 0.971 0.029
S03.4 Sprain and strain of jaw
0.000 0.971 0.029
S03.3 Dislocation of other and unspecified parts of head
0.000 0.971 0.029
S03.0 Dislocation of jaw
0.000 0.971 0.029
S05.7 Avulsion of eye
0.000 0.971 0.028
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.971 0.028
S05.5 Penetrating wound of eyeball with foreign body
0.000 0.971 0.028
S05.4 Penetrating wound of orbit with or without foreign body
0.000 0.971 0.028
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.000 0.971 0.028
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.972 0.028
I51.4 Myocarditis, unspecified
0.001 0.972 0.028
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.972 0.028
S05.9 Injury of eye and orbit, part unspecified
0.000 0.972 0.028
S09.9 Unspecified injury of head
0.000 0.972 0.028
S02.4 Fracture of malar and maxillary bones
0.000 0.972 0.028
S02.1 Fracture of base of skull
0.000 0.972 0.028
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.972 0.028
K05.1 Chronic gingivitis
0.028 0.972 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.973 0.027
I47.0 Reentry ventricular arrhythmia
0.000 0.973 0.027
S02.5 Fracture of tooth
0.000 0.973 0.027
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.973 0.027
I65.2 Occlusion and stenosis of carotid artery
0.000 0.973 0.027
S02.81 Fractures of other skull and facial bones (open)
0.000 0.973 0.026
K05.2 Acute periodontitis
0.026 0.974 0.000
K05.4 Periodontosis
0.026 0.974 0.000
K05.0 Acute gingivitis
0.026 0.974 0.000
S01.4 Open wound of cheek and temporomandibular area
0.000 0.974 0.026
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.974 0.026
I49.4 Other and unspecified premature depolarisation
0.000 0.974 0.026
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.975 0.025
S02.61 Fracture of mandible (open)
0.000 0.975 0.025
K05.5 Other periodontal diseases
0.024 0.975 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.976 0.024
S03.1 Dislocation of septal cartilage of nose
0.000 0.976 0.023
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.976 0.024
S02.60 Fracture of mandible (closed)
0.000 0.977 0.022
I47.2 Ventricular tachycardia
0.000 0.978 0.022
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.978 0.022
S02.31 Fracture of orbital floor (open)
0.000 0.978 0.022
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.978 0.022
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.979 0.021
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.979 0.021
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.980 0.020
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.980 0.020
S02.51 Fracture of tooth (open)
0.000 0.980 0.019
J38.7 Other diseases of larynx
0.020 0.980 0.000
S01.5 Open wound of lip and oral cavity
0.000 0.981 0.019
I65.1 Occlusion and stenosis of basilar artery
0.000 0.981 0.019
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.981 0.019
K05.22 Aggressive periodontitis, generalized
0.019 0.981 0.000
I60 Subarachnoid haemorrhage
0.000 0.981 0.019
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.982 0.018
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.982 0.017
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.982 0.017
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.982 0.017
I68.0 Cerebral amyloid angiopathy
0.000 0.983 0.017
S06 Intracranial injury
0.000 0.983 0.017
S02.11 Fracture of base of skull (open)
0.000 0.983 0.016
S02.10 Fracture of base of skull (closed)
0.000 0.984 0.016
I08.0 Disorders of both mitral and aortic valves
0.000 0.984 0.016

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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